Abubuwan gina jiki

Epigenetics na gina jiki kimiyya ce da ke nazarin tasirin abinci mai gina jiki akan maganganun kwayoyin halitta da samun damar chromatin .   Sashe ne na nau'ikan kwayoyin halitta masu gina jiki wanda ke mai da hankali kan tasirin abubuwan abinci masu rai akan abubuwan da suka faru na epigenetic . 

 Tarihi 
Canje-canje ga bayanan kwayoyin halittar yara da ke haifar da abinci mai gina jiki na tayin an lura da su tun farkon yunwar Dutch na 1944-1945 .      Saboda rashin abinci mai gina jiki a cikin iyaye mata masu juna biyu, yaran da aka haifa a lokacin wannan yunwa sun fi dacewa su nuna al'amuran lafiya kamar cututtukan zuciya, kiba, schizophrenia, damuwa, da jaraba.   

Masana ilimin halittu Randy Jirtle da Robert A. Waterland sun zama farkon majagaba na epigenetics na abinci mai gina jiki bayan sun buga binciken su game da tasirin abincin uwa mai ciki akan ayyukan halittar 'ya'yanta a cikin mujallar bincike Molecular and Cellular Biology a 2003.  

 Bincike 
Masu bincike a cikin epigenetics masu gina jiki suna nazarin hulɗar tsakanin kwayoyin halitta a cikin abinci da kwayoyin da ke sarrafa maganganun kwayoyin halitta, wanda ke kaiwa ga wuraren da aka fi mayar da hankali kamar kungiyoyin methyl na abinci da DNA methylation .    Abubuwan gina jiki da abubuwan abinci na bioactive suna shafar epigenetics ta hanyar hana ayyukan enzymatic da suka danganci DNA methylation da gyare-gyaren histone .  Saboda ana amfani da ƙungiyoyin methyl don murkushe ƙwayoyin halittar da ba a so, matakin uwa na cin abinci na methyl na iya canza yanayin bayyanar ɗanta sosai, musamman lokacin haɓakawa da wuri.  Bugu da ƙari kuma, abinci mai gina jiki zai iya rinjayar methylation yayin da tsarin ya ci gaba a cikin rayuwar mutum ta girma. Saboda haka, masu ilimin halitta masu gina jiki sun yi nazarin abinci a matsayin nau'i na bayyanar kwayoyin halitta. 

 Manazarta