Allurar rigakafin ciwon ciki

Alurar rigakafin mumps alluran rigakafi ce waɗanda ke hana mumps .  Lokacin da aka bai wa yawancin jama'a suna rage rikitarwa a matakin yawan jama'a .  An kiyasta tasirin lokacin da kashi 90% na yawan alurar riga kafi shine 85%.  Ana buƙatar allurai biyu don rigakafin dogon lokaci.  Ana ba da shawarar kashi na farko tsakanin watanni 12 zuwa 18.  Ana ba da kashi na biyu tsakanin shekaru biyu zuwa shekaru shida.  Amfani bayan fallasa a cikin waɗanda ba a rigaya ba na iya zama da amfani.

Illolin gaba gabaɗaya suna da laushi. World Health Organization (February 2007). "Mumps virus vaccines". Relevé Épidémiologique Hebdomadaire. 82 (7): 51–60. hdl:10665/240868. PMID 17304707. Yana iya haifar da ciwo mai sauƙi da kumburi a wurin allura da zazzabi mai sauƙi.  Ƙarin tasiri mai mahimmanci yana da wuya.  Shaida ba ta isa ba don haɗa maganin alurar riga kafi zuwa rikitarwa kamar tasirin jijiya.  Kada a ba da maganin ga mutanen da ke da juna biyu ko kuma suna da ƙarancin aikin garkuwar jiki .  Sakamako mara kyau a tsakanin yaran uwayen da suka karɓi maganin a lokacin daukar ciki, duk da haka, ba a rubuta su ba.   Ko da yake an samar da maganin a cikin ƙwayoyin kaji, yana da lafiya gabaɗaya don ba masu ciwon kwai . 

Yawancin kasashen da suka ci gaba da kuma kasashe da yawa a cikin kasashe masu tasowa sun haɗa da shi a cikin shirye-shiryensu na rigakafi sau da yawa a hade tare da kyanda da ƙwayar cutar kyanda da aka sani da MMR . World Health Organization (February 2007). "Mumps virus vaccines". Relevé Épidémiologique Hebdomadaire. 82 (7): 51–60. hdl:10665/240868. PMID 17304707. Akwai wani tsari tare da ukun da suka gabata da kuma rigakafin varicella (chickenpox) da aka sani da MMRV .  Ya zuwa shekarar 2005, kasashe 110 ne suka ba da rigakafin a matsayin wani bangare na shirye-shiryensu na rigakafi.  A yankunan da ake yawan yin allurar rigakafi ya haifar da raguwar cututtuka fiye da kashi 90 cikin 100.  An ba da kusan rabin biliyan na allurai iri ɗaya na rigakafin. 

 Tarihi 
A tsakiyar karni na ashirin, ba a kallon cututtukan mumps a tsakanin yara a matsayin wani muhimmin al'amari na kiwon lafiyar jama'a, amma mazan manya na iya haifar da kumburin jini mai raɗaɗi, wanda ya haifar da matsala ta musamman a tsakanin sojojin da ke kusa a lokacin yakin. A sakamakon haka, a lokacin yakin duniya na biyu (1939-1945), gwamnatin Amurka ta yi niyya don binciken kimiyya.  An ba da lasisin rigakafin cutar mump na farko a cikin 1948; ci gaba daga ƙwayoyin cuta marasa aiki, yana da tasiri na ɗan gajeren lokaci. 

Ingantattun alluran rigakafi sun zama na kasuwanci a cikin 1960s. World Health Organization (February 2007). "Mumps virus vaccines". Relevé Épidémiologique Hebdomadaire. 82 (7): 51–60. hdl:10665/240868. PMID 17304707. A cikin 1963, Maurice Hilleman na Merck &amp; Co. ya ɗauki samfurori na kwayar cutar mumps daga 'yarsa, wadda ta kamu da cutar; ta zama mai suna ga sakamakon Jeryl Lynn iri. Roos D. "How a New Vaccine Was Developed in Record Time in the 1960s". HISTORY. Retrieved 17 November 2020.  Gina kan ci gaban da aka samu na baya-bayan nan wanda ya haifar da rigakafin cutar shan inna da kyanda, an samo nau'ikan ƙwayoyin cuta na mumps a cikin ƙwai masu kaji da kuma al'adun ƙwayoyin amfrayo.  Sakamakon nau'ikan ƙwayoyin cuta ba su dace da ƙwayoyin ɗan adam ba, don haka an ce an rage su . A wasu lokuta ana kiran su da neuroattenuated ta ma'anar cewa waɗannan nau'ikan ba su da cutarwa ga jijiyoyin ɗan adam fiye da nau'in daji.  

Aikin Hilleman ya haifar da ingantaccen rigakafin mumps na farko, wanda ake kira Mumpsvax. An ba da izini a cikin 1967, ci gabanta na shekaru huɗu ya kafa rikodin don haɓaka mafi sauri na sabon rigakafin, Roos D. "How a New Vaccine Was Developed in Record Time in the 1960s". HISTORY. Retrieved 17 November 2020. rikodin daga baya ya zarce allurar COVID-19, wanda aka haɓaka cikin ƙasa da shekara guda. 

Alurar riga kafi akan mumps bai zama na yau da kullun ba har sai an haɗa Mumpsvax a cikin haɗin gwiwar rigakafin MMR na Merck, wanda ya yi niyya ga kyanda da rubella tare da mumps. Roos D. "How a New Vaccine Was Developed in Record Time in the 1960s". HISTORY. Retrieved 17 November 2020. Hviid A, Rubin S, Mühlemann K (March 2008). "Mumps". Lancet. 371 (9616): 932–944. doi:10.1016/S0140-6736(08)60419-5. PMID 18342688. S2CID 208793825.  An ba da lasisin MMR a shekara ta 1971, kuma kashi 40 cikin 100 na yaran Amurkawa sun sami haɗin gwiwar rigakafin ta 1974. A cikin 1977, Cibiyar Kula da Cututtuka da Cututtuka ta Amurka (CDC) ta ba da shawarar rigakafin cutar mumps (a matsayin wani ɓangare na MMR) ga duk yara sama da watanni 12, kuma a cikin 1998, CDC ta fara ba da shawarar allurar rigakafin kashi biyu na MMR. 

 Nau'ukan 
Yayin da rigakafin farko a cikin 1940s ya dogara ne akan ƙwayoyin cuta da ba a kunna ba, shirye-shiryen da suka biyo baya tun daga shekarun 1960 sun ƙunshi ƙwayoyin cuta masu rai waɗanda aka raunana. World Health Organization (February 2007). "Mumps virus vaccines". Relevé Épidémiologique Hebdomadaire. 82 (7): 51–60. hdl:10665/240868. PMID 17304707. Alurar rigakafin mumps yana cikin Jerin Mahimman Magunguna na Hukumar Lafiya ta Duniya . Akwai nau'ikan nau'ikan nau'ikan nau'ikan da ake amfani da su kamar na 2007. 

Mumpsvax alama ce ta Merck ta Jeryl Lynn nau'in rigakafi.  Wani bangare ne na rigakafin cutar MMR na Merck guda uku, kuma shine ma'aunin rigakafin mumps a cikin Amurka.  Ana ba da Mumpsvax ta hanyar allurar ƙwayar cuta mai rai wanda aka sake ginawa daga busasshiyar rigakafin ( lyophilized ). An daina samar da Mumpsvax a matsayin samfurin tsaye a cikin 2009. 

Kwayoyin da aka yi amfani da su a cikin al'ada, ƙwayoyin ƙwayoyin cuta da ake amfani da su, da ruwan dabbobi duk ana bincika su don wani abu mai ban sha'awa a matsayin wani ɓangare na samar da rigakafin. Ana shuka su a cikin Matsakaici 199 (mafita dauke da gishiri mai buffer, bitamin, amino acid, fetal bovine serum) tare da SPGA (sucrose, phosphate, glutamate, albumin mutum ) da neomycin . Aikin sarrafa albumin na ɗan adam yana amfani da hanyar Cohn sanyi ethanol rarrabuwa .

 Sauran nau'ikan 

 RIT 4385 sabon nau'i ne wanda aka samo daga nau'in Jeryl Lynn Hviid A, Rubin S, Mühlemann K (March 2008). "Mumps". Lancet. 371 (9616): 932–944. doi:10.1016/S0140-6736(08)60419-5. PMID 18342688. S2CID 208793825. ta Maurice Hilleman, mahaifin Jeryl Lynn.
 Smrodintsev da Klyachko sun haɓaka nau'in Leningrad-3 a cikin al'adun ƙwayoyin koda kuma ana amfani dashi tun 1950 a tsoffin ƙasashen Soviet.  Ana amfani da wannan rigakafin akai-akai a Rasha.
 An samo nau'in L-Zagreb da aka yi amfani da shi a cikin Croatia da Indiya daga nau'in Leningrad-3 ta hanyar wucewa . 
 An gabatar da nau'in Urabe a Japan, kuma daga baya an ba da lasisi a Belgium, Faransa da Italiya. An danganta shi da mafi yawan ƙwayar cutar sankarau (1/143 000 da 1/227 000 don JL),  kuma an watsar da shi a cikin ƙasashe da yawa. An tsara shi azaman MMR a Burtaniya.
 Nauyin Rubini da aka yi amfani da shi musamman a Switzerland ya rage yawan wuce gona da iri ta cikin amfrayo kaji, kuma daga baya ya nuna cewa yana da ƙarancin ƙarfi.  An gabatar da shi a cikin 1985. 

 Shigo da sigar mara inganci cikin Burtaniya ba bisa ka'ida ba 
Maganin cutar mumps na Monovalent (Mumpsvax) ya kasance a cikin Amurka lokacin da aka gabatar da MMR a Burtaniya, wanda ya maye gurbin MR (kyanda da rubella). Babu wani shiri na monovalent mai lasisin Burtaniya da ya taɓa samuwa.  Ana samun allurar rigakafin mumps na mumps kafin MMR, amma ana amfani da su akan iyakataccen sikeli.   Wannan ya zama batun muhawara mai yawa a ƙarshen karni na 20, tunda wasu iyaye sun gwammace su sami ɗayan abubuwan haɗin MMR. Shirye-shiryen rigakafin mumps guda ɗaya da aka shigo da shi cikin Burtaniya kuma ba shi da lasisi, ya tabbatar da cewa ba shi da inganci.  Rigakafin rigakafin cutar mumps a Burtaniya ya zama na yau da kullun a cikin 1988, wanda ya fara da MMR. Alamar Aventis-Pasteur "MMR-2" ta saba a cikin Burtaniya a cikin 2006

 Adana da kwanciyar hankali 
Sarkar sanyi shine babban abin la'akari a cikin allurar rigakafi, musamman a cikin ƙasashe masu ƙarancin ci gaba. Alurar rigakafin mumps yawanci a cikin firiji ne, amma suna da tsawon rabin rayuwa na kwanaki 65 a digiri 23 na ma'aunin celcius. "Immunizations, Vaccines and Biologicals - The Mumps Vaccine". World Health Organization. Archived from the original on 23 April 2006.

 Kara karantawa 



 Hanyoyin haɗi na waje 

 Mumps Vaccine at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

 Mumps (The History of Vaccines)
 Mumps Immunization. WHO

 Manazarta 
Rukuni:Rigakafi
Rukuni:Shafuka masu fassarorin da ba'a duba ba