Probiotics a cikin yara

Probiotics a cikin yara

Probiotics sune ƙwayoyin cuta masu rai waɗanda kan haɓaka tare da da'awar cewa suna ba da fa'idodin kiwon lafiya lokacin cinyewa, gabaɗaya ta haɓakawa ko maido da flora na sashin hanji.  Ana ɗaukar magungunan ƙwayoyin cutar gabaɗaya amintattu don cinyewa, amma na iya haifar da hulɗar mai masaukin baki da kuma illolin da ba'a so a lokuta da ba kasafai ba.  Akwai ƙananan shaida cewa probiotics suna kawo fa'idodin kiwon lafiya da ake da'awa a gare su.
 Tasirin lafiya 
 Zawo 
Kamar yadda yawancin hanyoyin rigakafin cutar gudawa ke da illa (misali intussusception na hanji wajen yin amfani da allurar rigakafin rotavirus), masana kimiyya yanzu sun koma ga probiotics da fatan yin amfani da shi azaman kari don magance zawo mai tsanani.[6]  A cikin wani bita wanda ya rufe 34 masked, bazuwar, gwaje-gwaje masu sarrafa wuribo masu alaƙa da gudawa da ƙwayoyin cuta, an kammala cewa an sami raguwa gabaɗaya na 52% a cikin cututtukan cututtukan ƙwayoyin cuta, raguwar 8% na zawo na matafiyi, da raguwa 34%  a wasu nau'ikan gudawa mai tsanani.  Waɗannan lambobin suna nuna tasirin kariya daga zawo a cikin batutuwa ciki har da manya da yara.  Dangane da yara (shekaru <18), bakwai daga cikin gwaje-gwaje 12 da aka gudanar a cikin yanayin kiwon lafiyan jiki sun nuna raguwar zawo mai tsanani na 57%.  Babu wani muhimmin bambanci a cikin tasirin kariya na nau'ikan, wato Saccharomyces boulardii, Lactobacillus rhamnosus GG, Lactobacillus acidophilus, da Lactobacillus bulgaricus.[7]
An gano cewa maganin rigakafi yana da tasiri wajen magance zawo mai saurin yaduwa a cikin yara lokacin da aka kammala bita a shekara ta 2001, wanda ya shafi> yara 700 masu shekaru daga wata daya zuwa 48 masu fama da zawo.[8]  Binciken da aka yi a shekara ta 2002 ya nuna cewa Lactobacillus ya rage matsakaicin tsawon lokacin zawo mai tsanani da kwanaki 0.7 da mita stool da 1.6 a rana ta biyu na jiyya.  Sashi ya fi tasiri a fiye da biliyan goma da ke samar da mulkin mallaka na Lactobacillus a cikin sa'o'i 48 na farko na gudawa.[9]  Bugu da ƙari, an sami shaidun da ke nuna cewa probiotics na iya hana yara da jarirai daga gastroenteritis (wanda aka sani da ciwon ciki), wanda kuma zai iya haifar da zawo.[8].
 gudawa mai hade da kwayoyin cuta 
Wannan cuta gabaɗaya ana iya ƙididdige shi ta Clostridium difficile, ƙwayoyin cuta waɗanda wasu lokuta kan haifar da gudawa mai tsanani wanda aka sani da pseudomembranous colitis. A cikin nazarin gwaje-gwaje shida masu alaƙa da zawo mai alaƙa da ƙwayoyin cuta a cikin yara 766 masu shekaru wata ɗaya zuwa kimanin shekaru shida, an sami raguwa gabaɗaya a AAD lokacin da aka ciyar da yara ƙanana.  Ragewar, idan aka kwatanta da placebo, an gan shi daga 28.5% zuwa 11.9%;  a gaskiya ma, lokacin da aka ciyar da marasa lafiya probiotics tare da adadin maganin rigakafi, ƙananan marasa lafiya za su ci gaba da AAD daga kowane bakwai.  Magungunan rigakafi da aka ciyar da yaran a cikin gwajin sun haɗa da amoxicillin, penicillin da erythromycin. Shaidu sun nuna cewa S. boulardii ya fi dacewa wajen hana AAD a yara, Lactobacillus GG matsayi na biyu, da cakuɗen S. thermophilus da B. lactis in mun gwada da matsayi na ƙarshe. Ba za a iya yanke hukunci kan yadda probiotics za su iya rage haɗarin AAD daga kowane takamaiman nau'in ƙwayoyin cuta ba.
Ɗaya daga cikin hanyoyin da aka tsara na yadda probiotics ke karewa daga AAD shine ta hanyar daidaita tsarin kwayoyin halitta a cikin hanji.  Nazarin da suka shafi L. acidophilus da Bifidobacterium sun ba da shawarar cewa waɗannan ƙwayoyin cuta suna hana haɓakar ƙwayoyin cuta anaerobic masu ƙarfi, waɗanda ke haɓaka haɓaka yayin maganin rigakafi. A sakamakon haka, ana ganin cewa probiotics na iya canzawa da kuma hana sauye-sauye a cikin microflora na hanji wanda maganin rigakafi ke haifar da shi.

 Cutar zawo 
Cutar zawo ta kwayar cuta tana nufin nau'in gudawa da rotavirus ke haifarwa, ƙwayar cuta sau da yawa tana shafar yara da jarirai.  Wani bincike da aka yi na bincike guda tara da aka gudanar a baya (an gudanar da binciken a Kanada, Thailand, da Finland) ya nuna cewa wasu nau'ikan ƙwayoyin cuta ma suna da tasiri wajen magance cutar zawo a cikin yara da aka kwantar da su a asibiti.  Batutuwan waɗannan karatun sun kasance daga ɗaya zuwa sama da watanni 36.  Sakamakon binciken ya nuna cewa an rage tsawon lokacin rashin lafiya da kwanaki 0.7 akan matsakaita lokacin sanya yara kan maganin Lactobacillus.

Ko da yake har yanzu ba a san yadda probiotics ke yin hakan ba, a halin yanzu an gabatar da hanyoyin guda biyu.  Hanya ta farko tana nuna cewa Lactobacilli yana haɓaka haɓakar mucins na hanji (protein gliosylated), wanda saboda haka yana kare jiki daga cututtuka na hanji.

 Zawo mai dawwama =
Wani bita na 2013 ya nuna cewa probiotics suna da tasiri wajen magance zawo mai tsayi a cikin yara, kodayake ana buƙatar ƙarin bincike.  Ciwon gudawa mai jujjuyawa wani lamari ne da ke farawa da sauri amma kuma yana ɗaukar kwanaki 14 ko fiye;  A cikin ƙasashe masu tasowa yana da mahimmancin sanadin cututtuka da mace-mace a cikin yara 'yan kasa da shekaru biyar. Binciken ya nuna matsakaicin tsawon lokacin da aka rage ta kwanaki hudu da gajeriyar zaman asibiti;  An rage yawan stool a rana ta biyar.

 Allergy 
Ana ba da magungunan rigakafi ga iyaye mata masu shayarwa da yara ƙanana don hana eczema, amma akwai wasu shakku game da ƙarfin shaidar da ke tabbatar da wannan a al'ada.[13]
 Tsaro 
"Dalla-dalla da aka rubuta tsakanin cututtuka na tsarin jiki da kuma amfani da probiotic ba su da yawa kuma duk sun faru a cikin marasa lafiya da yanayin kiwon lafiya."[14] Da wuya, amfani da probiotics na iya haifar da bacteremia, fungemia da sepsis a cikin yara masu ƙananan tsarin rigakafi waɗanda suka riga sun kamu da rashin lafiya.  4]  Babu wata illa daga shan Lactobacillus.[12]

 Manazarta