Encephalitis lethargica

Encephalitis lethargica (EL) be form of brain inflamation wey be  initially characterize by fever, headache, double vision, psychosis, den lethargy. Insyd chao cases, dis gradually dey result insyd some degree of coma. Parkinson's anaa epilepsy go fi develop insyd de years following de initial illness.

De cause be unknown. Proposal dey include infection like influenza anaa autoimmune process. Insyd at least some cases, de disease dey spread between menners. Insyd pregnancy, ego fi affect de baby. De underlying mechanism dey involve inflammation of specific parts of de brain, de mesencephalon den de diencephalon. Na de Diagnosis dey base on symptoms after say dem rule out other potential cases.

Treatment dey based on de symptoms. Levodopa go fi result insyd significant, though temporary improvement. Outcomes dey depend on de associated complications. About a third of menners wey die. Chao wey survive cam turn permanent disabled.

Outbreaks of disease occur around d world wey start insyd 1916 till 1930 wey affect about 5 million menners. Outbreaks occurr prior, dem document less than 20 cases since. Constantin von Economo den Jean-René Cruchet wey first describe de condition insyd 1917. Dem sana dey bell am "sleeping sickness" anaa "sleepy sickness"; though eno dey relate to tsetse fly-transmitted sleeping sickness.

 Notable cases 
Notable cases dey include:

 Muriel "Kit" Richardson (née Hewitt), first wifey of actor Sir Ralph Richardson
 Der be speculation say na Adolf Hitler fi get encephalitis lethargica wen na he be a young adult (in addition to de more substantial case for Parkinsonism insyd ein later years).
 Mervyn Peake (1911–1968), author of de Gormenghast books.
 Those dem describe insyd de book Awakenings by de British neurologist Oliver Sacks.
 Jane Norton Grew Morgan, wifey of J. P. Morgan Jr.

 References 

 Read further 

 Describes the history of the disease, and the epidemic of the 1920s.






 External links 

  — item about the tracing of the infectious agent in encephalitis lethargica

Category:Ailments of unknown cause
Category:Encephalitis
Category:Unsolved problems insyd neuroscience
Category:Viral infections of de central nervous system
Category:Diseases dem name after discoverers
Category:Translated from MDWiki