Cyclobenzaprine

Cyclobenzaprine, dem sell under chaw brand names wey dey include, historically, Flexeril, be a muscle relaxer dem use give muscle spasms from musculoskeletal conditions of sudden onset. E no be useful insyd cerebral palsy. Dem dey take am by mouth.

Common side effects dey include headache, tiredness, dizziness, den dry mouth. Serious side effects fi include an irregular heartbeat. Der be no evidence of harm insyd pregnancy, buh na e no be well studied insyd dis population. E for no be used togeda plus MAOIs. How e dey work be unclear. Insyd any case, e be known to inhibit serotonin den norepinephrine reuptake den to block serotonin, adrenergic, histamine, den muscarinic acetylcholine receptors. Chemically, e be very similar to tricyclic antidepressants like amitriptyline.

Na dem approve cyclobenzaprine for medical use insyd de United States insyd 1977. E be available by prescription as a generic medication. Insyd 2023, na e be de 47th most commonly prescribed medication insyd de United States, plus more dan 13million prescriptions. Na e no be available insyd de United Kingdom as of 2012.

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Category:5-HT2A antagonists
Category:5-HT2B antagonists
Category:5-HT2C antagonists
Category:5-HT6 antagonists
Category:5-HT7 antagonists
Category:Alpha-1 blockers
Category:Alpha-2 blockers
Category:Dibenzocycloheptenes
Category:Dimethylamino compounds
Category:Drugs wey Johnson & Johnson develop
Category:Drugs plus unknown mechanisms of action
Category:H1 receptor antagonists
Category:M1 receptor antagonists
Category:M2 receptor antagonists
Category:M3 receptor antagonists
Category:Muscle relaxants
Category:Serotonin–norepinephrine reuptake inhibitors
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