Aspirin

Aspirin (/ˈæsp(ə)rɪn/) be de genericized trademark give acetylsalicylic acid (ASA), a nonsteroidal anti-inflammatory drug (NSAID) dem use to reduce pain, fever, den inflammation, den as an antithrombotic. Dem dey use aspirin to treat inflammatory conditions wey dey include Kawasaki disease, pericarditis, den rheumatic fever.

Dem sanso dey use aspirin long-term to help prevent further heart attacks, ischaemic strokes, den blood clots insyd people at high risk. For pain anaa fever, effects typically dey begin within 30 minutes. Aspirin dey work similarly to oda NSAIDs buh sanso dey suppress de normal functioning of platelets.

One common adverse effect be an upset stomach. More significant side effects dey include stomach ulcers, stomach bleeding, den worsening asthma. Bleeding risk be greater among those wey be older, suck alcohol, take oda NSAIDs, anaa be on oda blood thinners. Dem no dey recommend aspirin insyd de last part of pregnancy. Dem generally no dey recommend insyd kiddies plus viral infections secof de risk of Reye syndrome. High doses fi result in ringing insyd de ears.

A precursor to aspirin dem find insyd de bark of de willow tree (genus Salix), salicin, be metabolized insyd de human gut into de medicinally active compound salicylic acid wey na dem use am for ein health effects for at least 2,400 years. Na pharmacology seek a synthetic alternative. Insyd 1853, na de chemist Charles Frédéric Gerhardt treat de medicine sodium salicylate plus acetyl chloride to produce acetylsalicylic acid for de first time. Over de next 50 years, na oda chemists, mostly of de German company Bayer, establish de chemical structure wey dem devise more efficient production methods. Na Felix Hoffmann (anaa perhaps Arthur Eichengrün) of Bayer be de first to produce acetylsalicylic acid insyd a pure, stable form insyd 1897. By 1899, na Bayer dub dis drug Aspirin wey na dem dey sell am globally.

Aspirin be available widout medical prescription as a proprietary anaa generic medication insyd most jurisdictions. E be one of de most widely used medications globally, plus an estimated  (50 to 120 billion pills) consumed each year, wey e dey on de World Health Organization's List of Essential Medicines. Insyd 2023, e be de 46th most commonly prescribed medication insyd de United States, plus more dan 14million prescriptions.

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Category:1897 insyd Germany
Category:1897 insyd science
Category:Acetate esters
Category:Acetylsalicylic acids
Category:Antiplatelet drugs
Category:Drugs wey Bayer develop
Category:Brands wey cam be generic
Category:Chemical substances for emergency medicine
Category:Commercialization of traditional medicines
Category:Covalent inhibitors
Category:Equine medications
Category:German inventions
Category:Hepatotoxins
Category:Nonsteroidal anti-inflammatory drugs
Category:Salicylic acids
Category:Salicylyl esters
Category:World Health Organization essential medicines
Category:Over-the-counter drugs insyd de United States
Category:Translated from MDWiki