Williams syndrome

Williams syndrome (WS), sanso be Williams–Beuren syndrome (WBS), be a genetic disorder wey dey affect chaw parts of de body. Facial features dey frequently include a broad forehead, underdeveloped chin, short nose, den full cheeks. Dem observe mild to moderate intellectual disability, particularly dey challenge plus visual spatial tasks such as drawing. Verbal skills be relatively unaffected. Chaw people get an outgoing personality, a happy disposition, an openness to engaging plus oda people, increased empathy den decreased aggression. Medical issues plus teeth, heart problems (especially supravalvular aortic stenosis), den periods of high blood calcium be common.

Williams syndrome be caused by a genetic abnormality, specifically a deletion of about 27 genes from de long arm of one of de two chromosome 7s. Typically, dis dey occur as a random event during de formation of de egg anaa sperm from wich a person dey develop. Insyd a small number of cases, dem dey inherit am from an affected parent insyd an autosomal dominant manner. Na dem link de different characteristic features to de loss of specific genes. Dem typically dey suspect de diagnosis base on symptoms wey na e be confirmed by genetic testing.

Interventions dey include special education programs den chaw types of therapy. Dem fi do surgery to correct heart problems. Dietary changes anaa medications fi be required for high blood calcium. Na dem first describe de syndrome insyd 1961 by New Zealander John C. P. Williams. Williams syndrome dey affect between one insyd 7,500 to 20,000 people at birth. Life expectancy be less dan dat of de general population, mostly secof de increased rates of heart disease.

 References 

 External links 

 GeneReview entry on Williams syndrome

Category:Autosomal monosomies den deletions
Category:Rare syndromes
Category:Syndromes wey dey affect de heart
Category:Syndromes wey dey affect teeth
Category:Syndromes wey dey affect de nervous system
Category:Syndromic autism
Category:Syndromes plus craniofacial abnormalities
Category:Syndromes plus intellectual disability
Category:Translated from MDWiki