Diazepam

Diazepam, dem sell under de brand name Valium among odas, be a medication of de benzodiazepine family wey dey act as an anxiolytic. Dem dey use am to treat a range of conditions, wey dey include anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, den restless legs syndrome. E sanso fi be used to cause memory loss during certain medical procedures. Dem fi take am orally (by mouth), as a suppository dem insert into de rectum, intramuscularly (dem inject into muscle), intravenously (injection into a vein) anaa dem use as a nasal spray. Wen na dem inject am intravenously, effects dey begin insyd one to five minutes den dey last up to an hour. When dem take am by mouth, effects dey begin after 15 to 60 minutes.

Common side effects dey include sleepiness den trouble plus coordination. Serious side effects be rare. Dem dey include increased risk of suicide, decreased breathing, den a paradoxical increased risk of seizures if dem use too frequently insyd those plus epilepsy. Occasionally, excitement anaa agitation fi occur. Long-term use fi result in tolerance, dependence, den withdrawal symptoms on dose reduction. Abrupt stopping after long-term use fi be potentially dangerous. After stopping, cognitive problems fi persist for six months anaa longer. Dem no dey recommend during pregnancy anaa breastfeeding. Ein mechanism of action dey work by increasing de effect of de neurotransmitter gamma-aminobutyric acid (GABA).

Na dem patent diazepam insyd 1959 by Hoffmann-La Roche. Na e be one of de most frequently medications dem prescribe insyd de world since ein launch insyd 1963. Insyd de United States na e be de best-selling medication between 1968 den 1982, dey sell more dan 2billion tablets insyd 1978 alone. Insyd 2023, na e be de 183rd most commonly medication dem prescribe insyd de United States, plus more dan 2million prescriptions. Insyd 1985, na de patent end, wey der be more dan 500 brands available on de market. E dey on de World Health Organization's List of Essential Medicines.

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Category:21-Hydroxylase inhibitors
Category:Anxiolytics
Category:Benzodiazepines
Category:Chemical substances for emergency medicine
Category:Chloroarenes
Category:Euphoriants
Category:Drugs wey Genentech develop
Category:Drugs wey Hoffmann-La Roche develop
Category:Glycine receptor antagonists
Category:Hallucinogen antidotes
Category:Lactams
Category:TSPO ligands
Category:World Health Organization essential medicines
Category:Translated from MDWiki