Sarcoidosis

Sarcoidosis, dem sanso know as Besnier–Boeck–Schaumann disease, be a non-infectious granulomatous disease wey dey involve abnormal collections of inflammatory cells wey dey form lump dem know as granulomata. De disease usually dey begin insyd de lungs, skin, anaa lymph nodes. Less commonly affected be de eyes, liver, heart, den brain, though any organ fi be affected. De signs den symptoms dey depend on de organ involved. Often, no symptoms anaa mild symptoms per be seen. Wen e affect de lungs, wheezing, coughing, shortness of breath, anaa chest pain fi occur. Sam fi get Löfgren syndrome, plus fever, enlarged hilar lymph nodes, arthritis, den a rash dem know as erythema nodosum.

De cause of sarcoidosis be unknown. Sam believe e fi be secof an immune reaction to a trigger such as an infection anaa chemicals insyd those wey be genetically predisposed. Those plus affected family members be at greater risk. Diagnosis partly be based on signs den symptoms, wich fi be supported by biopsy. Findings wey dey make am likely dey include large lymph nodes at de root of de lung on both sides, high blood calcium plus a normal parathyroid hormone level, anaa elevated levels of angiotensin-converting enzyme insyd de blood. Dem for make de diagnosis only after dem exclude oda possible causes of similar symptoms such as tuberculosis.

Sarcoidosis fi resolve widout any treatment within a few years. However, sam people fi get long-term anaa severe disease. Sam symptoms fi be improved plus de use of anti-inflammatory drugs such as ibuprofen. Insyd cases wer de condition dey cause significant health problems, steroids such as prednisone be indicated. Medications such as methotrexate, chloroquine, anaa azathioprine occasionally fi be used in an effort to decrease de side effects of steroids. De risk of death be 1–7%. De chance of de disease returning insyd sam bro wey na dem previously get am be less dan 5%.

Insyd 2015, na pulmonary sarcoidosis den interstitial lung disease affect 1.9 million people globally wey na e result in 122,000 deaths. E be most common insyd Scandinavians, buh dey occur insyd all parts of de world. Insyd de United States, risk be greater among black dan white people. E usually dey begin between de ages of 20 den 50. E dey occur more often insyd women dan men. Na de English doctor Jonathan Hutchinson first describe sarcoidosis insyd 1877 as a non-painful skin disease.

 References 

 External links 

 Sarcoidosis UK Information Hub


Category:Ailments of unknown cause
Category:Lung disorders
Category:Abdominal pain
Category:Monocyte- den macrophage-related cutaneous conditions
Category:Steroid-responsive inflammatory conditions
Category:Translated from MDWiki