Pregabalin

Pregabalin, dem sell under de brand name Lyrica among odas, be an anticonvulsant, analgesic, den anxiolytic amino acid medication dem use to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, generalized anxiety disorder (GAD), den shingles. Pregabalin sanso get antiallodynic properties. Ein use insyd epilepsy be as an add-on therapy give partial seizures. Wen dem use before surgery, e dey reduce pain buh dey result in greater sedation den visual disturbances. Dem dey take am by mouth.

Common side effects fi include headache, dizziness, sleepiness, euphoria, confusion, trouble plus memory, poor coordination, dry mouth, problems plus vision, den weight gain. Serious side effects fi include angioedema, kidney damage, den seizures.

As plus all oda drugs dem approve by de FDA for treating epilepsy, de pregabalin labeling dey warn of an increased suicide risk wen dem combine plus oda drugs. Wen dem take pregabalin at high doses over a long period of time, addiction fi occur, buh if dem take am at usual doses de risk be low. Ein use during pregnancy anaa breastfeeding be of unclear safety.

E be a gabapentinoid medication wich be a class of drugs within de derivatives of γ-aminobutyric acid (GABA analogues), an inhibitory neurotransmitter. Although pregabalin be inactive at GABA receptors den GABA synapses, e dey act by binding specifically to de α2δ-1 protein wey na dem first describe as an auxiliary subunit of voltage-gated calcium channels.

Na dem approve pregabalin for medical use insyd de United States insyd 2004. Insyd de US, pregabalin be a Schedule V controlled substance under de Controlled Substances Act of 1970, wich dey mean say de drug get low abuse potential compared to substances insyd Schedules I-IV, however, der still be a potential for misuse. E be available as a generic medication. Insyd 2023, na e be de 78th most commonly prescribed medication insyd de United States, plus more dan 8million prescriptions.

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Category:Analgesics
Category:Anticonvulsants
Category:Anxiolytics
Category:Drugs wey Pfizer develop
Category:Euphoriants
Category:GABA analogues
Category:Gabapentinoids
Category:Gamma-Amino acids
Category:Aminomethyl compounds
Category:CYP2A6 inhibitors
Category:Translated from MDWiki