Myelodysplastic syndrome

A myelodysplastic syndrome (MDS) be one of a group of cancers insyd wich blood cells insyd de bone marrow no dey mature, den as a result, no dey develop into healthy blood cells. Early on, dem no dey see symptoms typically. Later, symptoms fi include fatigue, shortness of breath, bleeding disorders, anemia, anaa frequent infections. Sam types fi develop into acute myeloid leukemia.

Risk factors dey include previous chemotherapy anaa radiation therapy, exposure to certain chemicals such as tobacco smoke, pesticides, den benzene, den exposure to heavy metals such as mercury anaa lead. Problems plus blood cell formation result in sam combination of low red blood cell, platelet, den white blood cell counts. Sam types of MDS dey cause an increase insyd de production of immature blood cells (dem call blasts), insyd de bone marrow anaa blood. De different types of MDS be identified based on de specific characteristics of de changes insyd de blood cells den bone marrow.

Treatments fi include supportive care, drug therapy, den hematopoietic stem cell transplantation. Supportive care fi include blood transfusions, medications to increase de making of red blood cells, den antibiotics. Drug therapy fi include de medications lenalidomide, antithymocyte globulin, den azacitidine. Sam people fi be cured by chemotherapy followed by a stem-cell transplant from a donor.

About seven per 100,000 people be affected by MDS; about four per 100,000 people newly acquire de condition each year. De typical age of onset be 70 years. De prognosis dey depend on de type of cells affected, de number of blasts insyd de bone marrow anaa blood, den de changes present insyd de chromosomes of de affected cells. De average survival time dey follow diagnosis be 2.5 years. Na dem first recognize MDS insyd de early 1900s; wey na e cam be called myelodysplastic syndrome insyd 1976.

 People plus MDS 
 Michael Brecker, musician
 Laurentino Cortizo, de Presido of Panama
 Roald Dahl, writer
 Nora Ephron, journalist, writer, den filmmaker
 Pat Hingle, actor

 Paul Motian, musician
 Amrish Puri, actor
 Carl Sagan, astrophysicist
 Susan Sontag, author
 Norm Macdonald, comedian

 References 

 External links 



Category:Myeloid neoplasia
Category:Syndromes wey dey affect blood
Category:Translated from MDWiki