Propofol

Propofol be de active component of an intravenous anesthetic formulation dem use for induction den maintenance of general anesthesia. Na dem approve de formulation under de brand name Diprivan. Na dem since release chaw generic versions. Dem use intravenous administration to induce unconsciousness, after wich dem fi maintain anesthesia dey use a combination of medications. Na dem manufacture am as part of a sterile injectable emulsion formulation dey use soybean oil den lecithin, wey dey give am a white milky coloration.

Dem compare to oda anesthetic agents, recovery from propofol-induced anesthesia generally be rapid wey be associated plus less frequent side effects (e.g., drowsiness, nausea, vomiting). Dem fi use propofol prior to diagnostic procedures wey dey require anesthesia, insyd de management of refractory status epilepticus, den for induction anaa maintenance of anesthesia prior to den during surgeries. E fi be administered as a bolus anaa an infusion, anaa as a combination of de two.

Dem first synthesize am insyd 1973 by John B. Glen, a British veterinary anesthesiologist wey dey work give Imperial Chemical Industries (ICI, later AstraZeneca), na dem  introduce propofol for therapeutic use as a lipid emulsion insyd de United Kingdom den New Zealand insyd 1986. Na propofol (Diprivan) receive FDA approval insyd October 1989. E be on de World Health Organization's List of Essential Medicines.

 References 
Category:Translated from MDWiki

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Category:Drugs wey AstraZeneca develop
Category:Chemical substances for emergency medicine
Category:Dog medications
Category:General anesthetics
Category:GABAA receptor positive allosteric modulators
Category:GABAA receptor agonists
Category:Glycine receptor agonists
Category:Alkylphenols
Category:World Health Organization essential medicines
Category:Isopropyl compounds