Quetiapine

Quetiapine, dem sell under de brand name Seroquel among odas, be an atypical antipsychotic medication dem use insyd de treatment of schizophrenia, bipolar disorder, bipolar depression, den major depressive disorder. Despite e be widely prescribed as a sleep aid secof ein tranquillizing effects, de benefits of such use no fi outweigh de risk of undesirable side effects. Dem dey take am orally.

Common side effects dey include sedation, fatigue, weight gain, constipation, den dry mouth. Oda side effects dey include low blood pressure plus standing, seizures, high blood sugar, tardive dyskinesia, den neuroleptic malignant syndrome. Insyd older people plus dementia, ein use dey increase de risk of death. Ein use insyd de third trimester of pregnancy fi result insyd a movement disorder insyd de baby for sam time after birth. Dem dey believe quetiapine dey work by blocking a number of receptors, wey dey include those for serotonin den dopamine.

Na dem develop quetiapine insyd 1985 wey na dem approve for medical use insyd de United States insyd 1997. E be available as a generic medication. Insyd 2023, na e be de most prescribed antipsychotic den 60th most commonly prescribed medication insyd de United States, plus more dan 10million prescriptions. E be on de World Health Organization's List of Essential Medicines.

De drug be typically among two antipsychotics (de oda be olanzapine) to have superior efficacy for de treatment of bipolar disorder. Quetiapine be one of two antipsychotics per (de oda be cariprazine) wey dey produce equal efficacy as standalone therapies for mixed manic-depressive mood swings as dem dey do in combination plus an SSRI antidepressant. Buh e be less potent than clozapine, amisulpride, olanzapine, risperidone, den paliperidone in alleviating psychotic symptoms anaa treating schizophrenia.

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Category:Alpha-1 blockers
Category:Alpha-2 blockers
Category:Antidepressants
Category:Atypical antipsychotics
Category:Drugs wey AstraZeneca develop
Category:Dibenzothiazepines
Category:Ethers
Category:Glycol ethers
Category:H1 receptor antagonists
Category:Hallucinogen antidotes
Category:5-HT2A antagonists
Category:Hypnotics
Category:Mood stabilizers
Category:Piperazines
Category:Hydroxyethyl compounds
Category:Sedatives
Category:World Health Organization essential medicines
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