Fatal insomnia

Fatal insomnia be a neurodegenerative disease wey dey result in trouble sleeping as ein hallmark symptom. De majority of cases be familial (fatal familial insomnia [FFI]), wey dey stem from a mutation insyd de PRNP gene, plus de remainder of cases wey dey occur sporadically (sporadic fatal insomnia [sFI]). De problems plus sleeping typically dey start out gradually den worsen over time. Eventually, de patient go succumb to total insomnia (agrypnia excitata), most often wey dey lead to oda symptoms such as speech problems, coordination problems, den dementia. E dey result in death within a few months to a few years, wey der no be known disease-modifying treatment.

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Category:Neurodegenerative disorders
Category:Transmissible spongiform encephalopathies
Category:Unsolved problems insyd neuroscience
Category:Sleep disorders
Category:Rare diseases
Category:Sleeplessness den sleep deprivation
Category:Translated from MDWiki