MDMA

3,4-Methylenedioxymethamphetamine (MDMA), dem commonly know as ecstasy (tablet form), den molly (crystal form), be an empathogen–entactogenic drug plus stimulant den minor psychedelic properties. Insyd studies, dem dey use am alongside psychotherapy insyd de treatment of post-traumatic stress disorder (PTSD) den social anxiety insyd autism spectrum disorder. De purported pharmacological effects wey fi be prosocial dey include altered sensations, increased energy, empathy, den pleasure. Wen dem take am by mouth, effects dey begin insyd 30 to 45 minutes den dey last three to six hours.

 Uses 

 Recreational 

 Medical 

 Odas 
Sam religious practitioners dey use small doses of MDMA as an entheogen make e enhance prayer anaa meditation. Na dem dey use MDMA as an adjunct to New Age spiritual practices.Watson L, Beck J (1991). "New age seekers: MDMA use as an adjunct to spiritual pursuit" (PDF). Journal of Psychoactive Drugs. 23 (3): 261–70. doi:10.1080/02791072.1991.10471587. PMID 1685513. Archived from the original on 22 November 2004. Retrieved 28 April 2024.

 Forms 
MDMA be usually consumed by mouth. E sanso sam times be snorted.

 Effects 
For general, MDMA users report dem dey feel de onset of subjective effects within 30 to 60 minutes of oral consumption wey e dey reach peak effect for 75 to 120 minutes, wich then plateaus for about 3.5 hours. Na dem report de desired short-term psychoactive effects of MDMA e dey include:

 Euphoria – a sense of general well-being den happiness
 Increased self-confidence, sociability, den perception of facilitated communicationBetzler F, Viohl L, Romanczuk-Seiferth N (January 2017). "Decision-making in chronic ecstasy users: a systematic review". The European Journal of Neuroscience. 45 (1): 34–44. doi:10.1111/ejn.13480. PMID 27859780. S2CID 31694072. ...the addictive potential of MDMA itself is relatively small.
 Entactogenic effects—increased empathy anaa feelings of closeness plus odas den einself
 Dilated pupils
 Relaxation den reduced anxiety
 Increased emotionality
 A sense of inner peace
 Mild hallucination
 Enhanced sensation, perception, anaa sexuality 
 Altered sense of time

 Side effects 

 Short-term 
De immediate adverse effects of MDMA use fi include:
 Bruxism (grinding den clenching of de teeth)Carvalho M, Carmo H, Costa VM, Capela JP, Pontes H, Remião F, et al. (August 2012). "Toxicity of amphetamines: an update". Archives of Toxicology. 86 (8): 1167–231. Bibcode:2012ArTox..86.1167C. doi:10.1007/s00204-012-0815-5. PMID 22392347. S2CID 2873101.
 DehydrationKeane M (February 2014). "Recognising and managing acute hyponatraemia". Emergency Nurse. 21 (9): 32–6, quiz 37. doi:10.7748/en2014.02.21.9.32.e1128. PMID 24494770.
 Diarrhea
 Erectile dysfunction
 Hyperthermia
 Increased wakefulness anaa insomnia
 Increased perspiration den sweating
 Increased heart rate den blood pressure
 Increased psychomotor activity
 Loss of appetite"3,4-Methylenedioxymethamphetamine". Hazardous Substances Data Bank. National Library of Medicine. 28 August 2008. Archived from the original on 4 April 2019. Retrieved 22 August 2014.
 Nausea den vomiting
 Visual den auditory hallucinations (rarely)
Oda adverse effects wey fi occur anaa persist for up to a week following cessation of moderate MDMA use dey include:

 Physiological
 Insomnia
 Loss of appetite
 Tiredness anaa lethargy
 Trismus (lockjaw)
 Psychological
 Anhedonia
 Anxiety or paranoia
 Depression
 Impulsiveness
 Irritability
 Memory impairment
 Restlessness

Overdose
+ Symptoms of overdose System Minor anaa moderate overdose  Severe overdose Cardiovascular Disseminated intravascular coagulation
 Intracranial hemorrhage
 Severe hypertension anaa hypotension
 Hypotensive bleeding Central nervoussystem Hyperreflexia
 Agitation
 Mental confusion
 Paranoia
 Stimulant psychosis Cognitive den memory impairment potentially to de point of retrograde anaa anterograde amnesia
 Coma
 Convulsions
 Hallucinations
 Loss of consciousness
 Serotonin syndromeMusculoskeletal Muscle rigidity
 Rhabdomyolysis (i.e., rapid muscle breakdown) Respiratory Acute respiratory distress syndrome Urinary Acute kidney injury Oda Cerebral edema
 Hepatitis
 Hyperpyrexia (a life-threatening elevation of body temperature greater dan anaa equal to )
 Hyponatremia (syndrome of inappropriate antidiuretic hormone)
 References 

External links

 A Multi-Site Phase 3 Study of MDMA-Assisted Therapy for PTSD (MAPP2)


Category:5-HT1A agonists
Category:5-HT2A agonists
Category:5-HT2B agonists
Category:5-HT2C agonists
Category:Aphrodisiacs
Category:Entactogens
Category:Entheogens
Category:Euphoriants
Category:Experimental antidepressants
Category:Experimental entactogens
Category:German inventions
Category:Methamphetamines
Category:Methylenedioxyphenethylamines
Category:Psychedelic phenethylamines
Category:Serotonin-norepinephrine-dopamine releasing agents
Category:Serotonin receptor agonists
Category:Stimulants
Category:TAAR1 agonists
Category:TAAR1 antagonists
Category:VMAT inhibitors
Category:Translated from MDWiki