Oseltamivir

Oseltamivir, dem sell under de brand name Tamiflu among odas, be an antiviral medication dem use to treat den prevent influenza A den influenza B, viruses wey dey cause de flu. Chaw medical organizations dey recommend am insyd people wey get complications anaa dem be at high risk of complications within 48 hours of first symptoms of infection. Dem dey recommend am to prevent infection insyd those at high risk, buh no be de general population. De Centers for Disease Control and Prevention (CDC) dey recommend say clinicians use dema discretion to treat those at lower risk wey present within 48 hours of first symptoms of infection. Dem dey take am by mouth, either as a pill anaa liquid.

Recommendations wey dey regard oseltamivir be controversial as be criticisms of de recommendations. Na a 2014 Cochrane Review conclude say oseltamivir no dey reduce hospitalizations, den dat der be no evidence of reduction insyd complications of influenza. Na two meta-analyses conclude say benefits insyd those wey be oda wise healthy no dey outweigh ein risks. Dem sanso find little evidence wey dey regard whether treatment dey change de risk of hospitalization anaa death insyd high risk populations. However, na anoda meta-analysis find say na oseltamivir be effective for prevention of influenza at de individual den household levels.

Common side effects dey include vomiting, diarrhea, headache, den trouble sleeping. Oda side effects fi include psychiatric symptoms den seizures. Insyd de United States, e be recommended for influenza infections during pregnancy. Na a small number of pregnant women take am widout signs of problems. Dose adjustment fi be needed insyd those plus kidney problems.

Na dem approve oseltamivir for medical use insyd de US insyd 1999. Na e be de first neuraminidase inhibitor available by mouth. E dey on de World Health Organization's List of Essential Medicines buh na dem downgrade am to "complementary" status insyd 2017. Na dem approve a generic version insyd de US insyd 2016. Insyd 2023, na e be de 250th most commonly prescribed medication insyd de United States, plus more dan 1million prescriptions.

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Category:Acetamides
Category:Cyclohexenes
Category:Dermatoxins
Category:Ethyl esters
Category:Drugs wey Hoffmann-La Roche develop
Category:Drugs wey Genentech develop
Category:Gilead Sciences
Category:Neuraminidase inhibitors
Category:Prodrugs
Category:World Health Organization essential medicines
Category:Translated from MDWiki