Atorvastatin

Atorvastatin, dem sell under de brand name Lipitor among odas, be a statin medication dem use to prevent cardiovascular disease insyd those at high risk den to treat abnormal lipid levels. For de prevention of cardiovascular disease, statins be a first-line treatment insyd reducing cholesterol. Dem dey take am by mouth.

Common side effects fi include diarrhea, heartburn, nausea, muscle pain (typically mild den dose-dependent) den, less frequently, joint pain. Muscle symptoms often dey occur during de first year den be commonly influenced by pre-existing health issues den de nocebo effect. Chaw patients fi continue therapy plus dose adjustment anaa statin switching. Rare (<0.1%) buh serious side effects fi include rhabdomyolysis (severe muscle disorder), liver problems den diabetes. Ein use during pregnancy fi harm de fetus. Like all statins, atorvastatin dey work by inhibiting HMG-CoA reductase, an enzyme dem find insyd de liver wey dey play a role in producing cholesterol.

Na dem patent atorvastatin insyd 1986, wey na dem approve am for medical use insyd de United States insyd 1996. E be on de World Health Organization's List of Essential Medicines. E be available as a generic medication. Insyd 2023, na e be de most commonly prescribed medication insyd de United States, plus more dan 115million prescriptions filled for over 29 million people. Insyd Australia, na e be one of de top ten most prescribed medications between 2017 den 2023.

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Category:Anilides
Category:Diols
Category:4-Fluorophenyl compounds
Category:Isopropyl compounds
Category:Drugs wey Pfizer develop
Category:Pyrroles
Category:Statins
Category:Hydroxycarboxylic acids
Category:Translated from MDWiki