Sepsis

Sepsis be a potentially life-threatening condition wey dey arise wen de body ein response to infection dey cause injury to ein own tissues den organs.Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. (February 2016). "The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)". JAMA. 315 (8): 801–810. doi:10.1001/jama.2016.0287. PMC 4968574. PMID 26903338.Angus DC, van der Poll T (August 2013). "Severe sepsis and septic shock". The New England Journal of Medicine. 369 (9): 840–851. doi:10.1056/NEJMra1208623. PMID 23984731.

Dis initial stage of sepsis be followed by suppression of de immune system. Common signs den symptoms dey include fever, increased heart rate, increased breathing rate, den confusion."Sepsis Questions and Answers". cdc.gov. Centers for Disease Control and Prevention (CDC). 22 May 2014. Archived from the original on 4 December 2014. Retrieved 28 November 2014. Der sanso fi be symptoms wey be related to a specific infection, such as a cough plus pneumonia, anaa painful urination plus a kidney infection.Jui J, et al. (American College of Emergency Physicians) (2011). "Ch. 146: Septic Shock". In Tintinalli JE, Stapczynski JS, Ma OJ, Cline DM, Cydulka RK, Meckler GD (eds.). Tintinalli's Emergency Medicine: A Comprehensive Study Guide (7th ed.). New York: McGraw-Hill. pp. 1003–14. ISBN 9780071484800. De very young, old, den people plus a weakened immune system no fi get any symptoms specific to dema infection, wey dema body temperature fi be low anaa normal instead of e dey constitute a fever. Severe sepsis dey cause organ dysfunction anaa blood flow. De presence of low blood pressure, high blood lactate, anaa low urine output fi suggest poor blood flow. Septic shock be low blood pressure secof sepsis wey no dey improve after fluid replacement.

Sepsis be caused by chaw organisms wey dey include bacteria, viruses, den fungi. Common locations give de primary infection dey include de lungs, brain, urinary tract, skin, den abdominal organs. Risk factors dey include being very young anaa old, a weakened immune system from conditions such as cancer anaa diabetes, major trauma, den burns. A shortened sequential organ failure assessment score (SOFA score), dem know as de quick SOFA score (qSOFA), na e replace de SIRS system of diagnosis. qSOFA criteria for sepsis dey include at least two of de following three: increased breathing rate, change insyd de level of consciousness, den low blood pressure. Sepsis guidelines dey recommend make dem dey obtain blood cultures before starting antibiotics; however, de diagnosis no dey require de blood e be infected. Medical imaging be helpful wen you dey look for de possible location of de infection.Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. (February 2013). "Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012". Critical Care Medicine. 41 (2): 580–637. doi:10.1097/CCM.0b013e31827e83af. PMID 23353941. Oda potential causes of similar signs den symptoms dey include anaphylaxis, adrenal insufficiency, low blood volume, heart failure, den pulmonary embolism.

 References 
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 External links 

 SIRS, Sepsis, and Septic Shock Criteria Archived 17 February 2015 at the Wayback Machine



Category:Infectious diseases
Category:Intensive care medicine
Category:Medical emergencies
Category:Causes of amputation
Category:Neonatology