Gout

Gout (/ɡaʊt/ GOWT) be a form of inflammatory arthritis wey be characterized by recurrent attacks of pain insyd a red, tender, hot, den swollen joint, wey be caused by de deposition of needle-like crystals of uric acid dem know as monosodium urate crystals. Pain typically dey cam on rapidly, wey dey reach maximal intensity insyd less dan 12 hours. De joint for de base of de big toe be affected (Podagra) insyd about half of cases. E sanso fi result insyd tophi, kidney stones, anaa kidney damage.

Gout be secof persistently elevated levels of uric acid (urate) insyd de blood (hyperuricemia). Dis dey occur from a combination of diet, oda health problems, den genetic factors. For high levels, uric acid dey crystallize wey de crystals dey deposit insyd joints, tendons, den surrounding tissues, wey dey result insyd an attack of gout. Gout dey occur more commonly insyd those wey regularly dey suck beer anaa sugar-sweetened beverages; dem dey chop chow wey be high insyd purines such as liver, shellfish, anaa anchovies; anaa dem be overweight. Diagnosis of gout fi be confirmed by de presence of crystals insyd de joint fluid anaa insyd a deposit outsyd de joint. Blood uric acid levels fi be normal during an attack.

Treatment plus nonsteroidal anti-inflammatory drugs (NSAIDs), glucocorticoids, anaa colchicine dey improve symptoms. Once de acute attack subsides, levels of uric acid fi be lowered via lifestyle changes den insyd those plus frequent attacks, allopurinol anaa probenecid dey provide long-term prevention. Taking vitamin C wey dem get a diet high insyd low-fat dairy products fi be preventive.

 References 

 External links 

 Chisholm H, ed. (1911). "Gout" . Encyclopædia Britannica. Vol. 12 (11th ed.). Cambridge University Press. pp. 289–291.



Category:Arthritis
Category:Articles wey dey contain video clips
Category:Inborn errors of purine-pyrimidine metabolism
Category:Inflammatory polyarthropathies
Category:Rheumatology
Category:Steroid-responsive inflammatory conditions
Category:Uric acid
Category:Crystal deposition diseases
Category:Translated from MDWiki