Idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF), dem formerly know as cryptogenic fibrosing alveolitis, be a rare, progressive illness of de respiratory system, characterized by de thickening den stiffening of lung tissue, wey dey surround de air sacs, wey be associated plus de formation of scar tissue. E be a type of chronic pulmonary fibrosis characterized by a progressive den irreversible decline insyd lung function.

Symptoms typically dey include gradual onset of shortness of breath den a dry cough. Oda changes fi include feeling tired, den clubbing abnormally large den dome shaped finger den toenails. Complications fi include pulmonary hypertension, heart failure, pneumonia anaa pulmonary embolism.

De cause be unknown, hence de term idiopathic. Risk factors dey include cigarette smoking, gastroesophageal reflux disease, certain viral infections, den genetic predisposition. De underlying mechanism dey involve scarring of de lungs. Diagnosis dey require ruling out oda potential causes. E fi be supported by a high resolution CT scan anaa lung biopsy wich dey show usual interstitial pneumonia. E be a type of interstitial lung disease.

People often dey benefit from pulmonary rehabilitation den supplemental oxygen. Anti-fibrotic medications like pirfenidone anaa nintedanib fi slow de progression of de disease. Lung transplantation sanso fi be an option.

About 5 million people be affected globally. De disease newly dey occur insyd about 12 per 100,000 people per year. Those insyd dema 60s den 70s most be commonly affected. Males be affected more often dan females. Average life expectancy dey follow diagnosis be about four years. Na updated international guidelines dem publish insyd 2022, wich result insyd sam simplification insyd diagnosis den de removal of antacids as a possible adjunct therapy.

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Category:Respiratory diseases principally wey dey affect de interstitium
Category:Idiopathic diseases
Category:Translated from MDWiki