Zolpidem

Zolpidem, dem sell under de brand name Ambien among odas, be a medication dem primarily use for de short-term treatment of sleeping problems. Guidelines dey recommend say dem dey use am only after cognitive behavioral therapy for insomnia den after behavioral changes na dem try, such as sleep hygiene. E dey decrease de time to sleep onset by about fifteen minutes den at larger doses dey help people stay asleep longer. Dem dey take am by mouth wey e be available as conventional tablets, extended-release tablets, anaa sublingual tablets.

Common side effects dey include daytime sleepiness, headache, nausea, den diarrhea. More severe side effects dey include memory problems den hallucinations. While flumazenil, a GABAA receptor antagonist, fi reverse zolpidem ein effects, usually supportive care be all wey be recommended in overdose.

Zolpidem be a nonbenzodiazepine, anaa Z-drug, wich dey act as a sedative den hypnotic as a positive allosteric modulator at de GABAA receptor. E be an imidazopyridine den dey increase GABA effects insyd de central nervous system by e dey bind to GABAA receptors at de same location as benzodiazepines. E generally get a half-life of two to three hours. Dis, however, be increased insyd those plus liver problems.

Na dem approve zolpidem for medical use insyd de United States insyd 1992. Na e cam be available as a generic medication insyd 2007. Zolpidem be a schedule IV controlled substance insyd de US under de Controlled Substances Act of 1970 (CSA). Insyd 2023, na e be de 54th most commonly prescribed medication insyd de United States, plus more dan 11million prescriptions.

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Category:Acetamides
Category:Dimethylamino compounds
Category:Drugs wey Pfizer develop
Category:GABAA receptor positive allosteric modulators
Category:Hypnotics
Category:Imidazopyridines
Category:Medical controversies
Category:Nonbenzodiazepines
Category:Sanofi
Category:Hallucinogens
Category:Translated from MDWiki