Venlafaxine

Venlafaxine, dem sell under de brand name Effexor among odas, be an antidepressant medication of de serotonin–norepinephrine reuptake inhibitor (SNRI) class. Dem dey use am to treat major depressive disorder, generalized anxiety disorder, panic disorder, den social anxiety disorder. Na studies show say venlafaxine dey improve post-traumatic stress disorder (PTSD) as a recommended first-line treatment. Dem sanso fi use am for chronic neuropathic pain. Dem dey take am orally (dem swallow by mouth). E sanso be available as de salt venlafaxine besylate (venlafaxine benzenesulfonate monohydrate) insyd an extended-release formulation (Venbysi XR).

Common side effects dey include loss of appetite, constipation, dry mouth, dizziness, sweating, insomnia, drowsiness den sexual problems. Severe side effects dey include an increased risk of suicide, mania, den serotonin syndrome. Antidepressant withdrawal syndrome fi occur if dem stop. Na a meta-analysis of randomized trials insyd depression find an increased rate of serious adverse events, particularly sexual dysfunction den anorexia, den chaw non-serious adverse effects, wey dey include nervousness, asthenia, den tremor. Der be concerns dem use during de later part of pregnancy fi harm de baby. Venlafaxine ein mechanism of action no be entirely clear, buh e dey seem to be related to de potentiation of de activity of sam neurotransmitters insyd de brain.

Na dem approve venlafaxine for medical use insyd de United States insyd 1993. E be available as a generic medication. Insyd 2023, na e be de 51st most commonly prescribed medication insyd de United States, plus more dan 13million prescriptions.

 References 
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Category:Antidepressants
Category:CYP2D6 inhibitors
Category:Dimethylamino compounds
Category:Dopamine reuptake inhibitors
Category:Drugs wey Pfizer develop
Category:Methoxyphenethylamines
Category:4-Methoxyphenyl compounds
Category:Serotonin–norepinephrine reuptake inhibitors
Category:Sigma agonists
Category:Tertiary alcohols
Category:Drugs wey Wyeth develop
Category:Translated from MDWiki