Naltrexone

Naltrexone, dem sell under de brand name Revia among odas, be a medication dem primarily use to manage alcohol use anaa opioid use disorder by reducing cravings den feelings of euphoria dem associate plus substance use disorder. Na dem sanso find am effective insyd de treatment of oda addictions wey fi be used give dem off-label. Dem dey take am orally anaa by injection into a muscle. Effects dey begin within 30 minutes, though a decreased desire for opioids fi take a few weeks to occur.

Side effects fi include trouble sleeping, anxiety, nausea, den headaches. Insyd those still on opioids, opioid withdrawal fi occur. Ein use no be recommended insyd people plus liver failure. E be unclear if ein use be safe during pregnancy. Naltrexone be an opioid antagonist wey e dey work by blocking de effects of opioids, wey dey include both opioid drugs as well as opioids dem naturally produce insyd de brain.

Na dem first make naltrexone insyd 1965 wey na dem approve am for medical use insyd de United States insyd 1984. Naltrexone, as naltrexone/bupropion (brand name Contrave), dem sanso use am to treat obesity. E dey on de World Health Organization's List of Essential Medicines. Insyd 2021, na e be de 254th most commonly prescribed medication insyd de United States, plus more dan 1million prescriptions.

References

 External links 

Category:Alcohol den health
Category:Cyclopropyl compounds
Category:Delta-opioid receptor antagonists
Category:4,5-Epoxymorphinans
Category:Ethers
Category:GABAA receptor negative allosteric modulators
Category:Hallucinogen antidotes
Category:Hepatotoxins
Category:Kappa-opioid receptor agonists
Category:Kappa-opioid receptor antagonists
Category:Cyclic ketones
Category:Mu-opioid receptor antagonists
Category:Hydroxyarenes
Category:World Health Organization essential medicines
Category:Diols
Category:Tertiary alcohols
Category:Translated from MDWiki