Dextroamphetamine

Dextroamphetamine be a central nervous system (CNS) stimulant den enantiomer of amphetamine wey be used insyd de treatment of attention deficit hyperactivity disorder (ADHD) den narcolepsy. E sanso be used illicitly to enhance cognitive den athletic performance, den recreationally as an aphrodisiac den euphoriant. Dextroamphetamine generally be regarded as de prototypical stimulant.

De amphetamine molecule dey exist as two enantiomers, levoamphetamine den dextroamphetamine. Dextroamphetamine be de dextrorotatory, anaa 'right-handed', enantiomer den dey exhibit more pronounced effects on de central nervous system dan levoamphetamine. Pharmaceutical dextroamphetamine sulfate be available as both a brand name den generic drug insyd a variety of dosage forms. Dextroamphetamine sam times be prescribed as de inactive prodrug lisdexamfetamine.

Side effects of dextroamphetamine at therapeutic doses dey include elevated mood, decreased appetite, dry mouth, excessive grinding of de teeth, headache, increased heart rate, increased wakefulness anaa insomnia, anxiety, den irritability, among odas. At excessive doses, psychosis (i.e., hallucinations, delusions), addiction, den rapid muscle breakdown fi occur. However, for individuals plus pre-existing psychotic disorders, der fi be a risk of psychosis even at therapeutic doses.

Dextroamphetamine, like oda amphetamines, dey elicit ein stimulating effects via chaw distinct actions: e dey inhibit anaa dey reverse de transporter proteins give de monoamine neurotransmitters (namely de serotonin, norepinephrine den dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) anaa insyd a TAAR1 independent fashion wen der be high cytosolic concentrations of de monoamine neurotransmitters wey e dey release dese neurotransmitters from synaptic vesicles via vesicular monoamine transporter 2 (VMAT2). E sanso dey share chaw chemical den pharmacological properties plus human trace amines, particularly phenethylamine den , de latter be an isomer of amphetamine dem produce within de human body. E be available as a generic medication. Insyd 2022, na mixed amphetamine salts (Adderall) be de 14th most commonly prescribed medication insyd de United States, plus more dan 34million prescriptions.

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Category:Amphetamine
Category:Anorectics
Category:Aphrodisiacs
Category:Antihypotensive agents
Category:Attention deficit hyperactivity disorder management
Category:Drugs wey dey act on de nervous system
Category:Enantiopure drugs
Category:Ergogenic aids
Category:Euphoriants
Category:Excitatory amino acid reuptake inhibitors
Category:Human drug metabolites
Category:Monoaminergic activity enhancers
Category:Nootropics
Category:Norepinephrine-dopamine releasing agents
Category:Pro-motivational agents
Category:Stimulants
Category:Substituted amphetamines
Category:TAAR1 agonists
Category:VMAT inhibitors
Category:Wakefulness-promoting agents
Category:World Anti-Doping Agency prohibited substances
Category:Translated from MDWiki