Cholangiocarcinoma

Cholangiocarcinoma, dem sanso know as bile duct cancer, be a type of cancer wey dey form insyd de bile ducts. Symptoms of cholangiocarcinoma fi include abdominal pain, yellowish skin, weight loss, generalized itching, den fever. Light colored stool anaa dark urine sanso fi occur. Oda biliary tract cancers dey include gallbladder cancer den cancer of de ampulla of Vater.

Risk factors give cholangiocarcinoma dey include primary sclerosing cholangitis (an inflammatory disease of de bile ducts), ulcerative colitis, cirrhosis, hepatitis C, hepatitis B, infection plus certain liver flukes, den sam congenital liver malformations. Chaw people get no identifiable risk factors. De diagnosis be suspected based on a combination of blood tests, medical imaging, endoscopy, den sam times surgical exploration. De disease be confirmed by examination of cells from de tumor under a microscope. E typically be an adenocarcinoma (a cancer wey dey form glands anaa dey secrete mucin).

Cholangiocarcinoma typically be incurable at diagnosis, wich be why early detection be ideal. Insyd dese cases palliative treatments fi include surgical resection, chemotherapy, radiation therapy, den stenting procedures. Insyd about a third of cases wey dey involve de common bile duct den, less commonly, plus oda locations, de tumor fi be completely removed by surgery, wey dey offer a chance of a cure. Even wen surgical removal be successful, chemotherapy den radiation therapy be generally recommended. Insyd sam instances, surgery fi include a liver transplantation. Even wen surgery be successful, de 5-year survival probability typically be less dan 50%.

Cholangiocarcinoma be rare insyd de Western world, plus estimates of e dey occur insyd 0.5–2 people per 100,000 per year. Rates be higher insyd Southeast Asia wer liver flukes be common. Rates insyd parts of Thailand be 60 per 100,000 per year. E typically dey occur insyd people insyd dema 70s, den insyd de 40s for those plus primary sclerosing cholangitis. Na rates of cholangiocarcinoma within de liver insyd de Western world increase.

 References 

 External links 

 American Cancer Society Detailed Guide to Bile Duct Cancer.
 Patient information on extrahepatic bile duct tumors, from the National Cancer Institute.
 Cancer.Net: Bile Duct Cancer 
 Cholangiocarcinoma Foundation
 World Cholangiocarcinoma Day

Category:Digestive system neoplasia
Category:Infectious causes of cancer
Category:Rare cancers
Category:Translated from MDWiki