Modafinil

Modafinil, dem sell under de brand name Provigil among odas, be a central nervous system (CNS) stimulant den eugeroic (wakefulness promoter) medication dem use primarily to treat narcolepsy, a sleep disorder wey be characterized by excessive daytime sleepiness den sudden sleep attacks. Dem sanso approve modafinil for stimulating wakefulness insyd people plus sleep apnea den shift work sleep disorder. Dem dey take am by mouth. Modafinil no be approved by de US Food and Drug Administration (FDA) for use insyd people under 18 years old.

Common side effects of modafinil dey include anxiety, insomnia, dizziness, den headache. Modafinil get potential for causing severe allergic reactions, psychiatric effects, hypersensitivity, adverse interactions plus prescription drugs, den misuse anaa abuse. Modafinil fi harm de fetus if dem take am during anaa two months prior to pregnancy.

While dem dey use modafinil as a cognitive enhancer, anaa "smart drug", among healthy individuals wey dey seek improved focus den productivity, ein use outsyd medical supervision dey raise concerns regarding potential misuse anaa abuse. Na research on de cognitive enhancement effects of modafinil insyd non-sleep deprived individuals yield mixed results, plus sam studies wey dey suggest modest improvements in attention den executive functions, while odas dey show no significant benefits anaa a decline in cognitive functions at high doses.

De mechanism of action no be fully defined, buh dem dey think e dey act mainly as an atypical dopamine transporter inhibitor wey modestly dey increase dopamine insyd cortical den striatal regions widout de rapid signaling dem see plus classical stimulants. Dis effect be accompanied by activation of noradrenergic, orexin, histamine, glutamate, den GABA systems wey togeda dey promote stable wakefulness den cortical activation. Dese combined actions likely dey explain modafinil ein wake-promoting den cognitive effects plus a lower risk of euphoria den abuse dan amphetamine-like stimulants.

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Category:1994 introductions
Category:French inventions
Category:Acetamides
Category:Benzhydryl compounds
Category:CYP3A4 inducers
Category:CYP2A6 inhibitors
Category:D2 receptor agonists
Category:Dermatoxins
Category:Dopamine reuptake inhibitors
Category:Drugs plus unknown mechanisms of action
Category:Nootropics
Category:Pro-motivational agents
Category:Racemic mixtures
Category:Stimulants
Category:Sulfoxides
Category:Wakefulness-promoting agents
Category:Modafinil analogues
Category:Attention deficit hyperactivity disorder management
Category:Narcolepsy
Category:CYP2C9 inhibitors
Category:CYP2C19 inhibitors
Category:Translated from MDWiki