Now may our God and Father himself, and our Lord Jesus Christ, direct our way to you;
The apostle asked God his Father and Jesus his Lord to clear the way so he and his fellow missionaries could return to Thessalonica. He addressed two members of the Godhead in prayer. He regarded both of these as God as is clear from his use of a singular verb ("direct") with a plural subject. "Himself" emphasizes Paul’s dependence on God to grant his request.