Yes, though you offer me your burnt offerings and meal-offerings, I will not accept them; Neither will I regard the peace offerings of your fat animals.
Now that is a term that is one of just total despair. You say, "Alas, alas," that means, "We've had it." That's just total despair. We don't use that term anymore, but it's one that just signifies, really, the end of the world.