As I exhorted you to stay at Ephesus when I was going into Macedonia, that you might charge certain men not to teach a different doctrine,

 There are the irreverent (asebeis, G765) . Asebeis is a terrible word. It describes not indifference nor the lapse into sin. It describes "positive and active irreligion," the spirit which defiantly withholds from God that which is his right. It describes human nature "in battle array against God." 