Let no one deceive you in any way. For it will not be, unless the departure comes first, and the man of sin is revealed, the son of destruction,
Some have referred it to a great apostasy from the Christian church, particularly on account of persecution, which would occur before the destruction of Jerusalem. The “coming of the Lord” they suppose refers to the destruction of the holy city, and according to this, the meaning is, that there would be a great apostasy before that event would take place. Of this opinion was Vitringa, who refers the “apostasy” to a great defection from the faith which took place between the time of Nero and Trajan.