Therefore he who rejects doesn't reject man, but God, who has also given his Holy Spirit to you.
despiseth not man, but God: It is not just the rejection of an invitation or of the messenger who brings it but also the rejection of the One Who gives it. Jesus made a similar assertion in Luke 10:16. When God sends a message by a messenger, to reject that message is to reject God himself. Those who speak disparagingly about the New Testament ought to take note of the dire warning here. As Fields says, "Note that it is in the voluntary power of a man to resist or accept truth. But it is not in man’s power to escape the consequences of that choice" (108).