胃腸道基質腫瘤

胃腸道基質腫瘤（，簡稱GISTs），為最常見的消化道間質腫瘤。GIST源自於卡氏間質細胞等平滑肌節律細胞。本疾病一般是因為突變所致（85%），少數則由（10%）、BRAF激酶基因突變引起。95%的GIST在c-Kit（CD117）免疫染色下會呈陽性。腫瘤最常見於胃部（66%），但源發於胃部的GIST一般相較於源發於消化道以外的GIST，惡性度會較低。GIST的影響範圍不限定於腸道，而可以遍及食道、胃、小腸、大腸及直腸；而隨着GIST在消化道的不同部位發生，病者亦會出現不同的病徵。

參考文獻

外部連結
 醫學研究連結 
  American Society of Clinical Oncology  "Other Gastrointestinal Cancer" Abstracts (2005)
 病患導向之網站 
 GIST Support International , An international organization for the support of GIST patients, families, and friends. Includes detailed information from some of the foremost experts on GIST, links to research, treatment options, GIST registry, adult and pediatric listservs, and affiliated GSI-Wiki. 
Life Raft Group International GIST Advocacy Organization. Provides support to patients & families, through information, education, and innovative research.
 GIST Info  Patient links, includes information on new clinical trials and research
American Cancer Society Patient Guide to GIST tumors.
 GIST 胃腸不可Blog

胃肠癌症