CRONaxal

benaGene, also known as Jubilance, also known as CRONaxal, also known as GilaxalGliaxal renamed CRONaxal in 2014, is marketed by Terra Biological LLC as a supplement, or or whatever they're selling it as this month. CRONaxal was "specially formulated" for people with primary brain tumours. Terra Biological say it contains a substance called which they also market as a treatment for the unrelated conditionsFDA says be suspicious of products which claim to treat unrelated conditions Amyotrophic Lateral Sclerosis,A copy of http://alsmedicalfood.com/ , (archived February 2017). Pre Menstrual Syndrome,A copy of http://endpmsanger.com/about-us (archived February 2017). tremor,A copy of http://tremorstop.com/ (archived February 2017). and doping athletes.A copy of http://endurance4athletes.com/ (archived February 2017). Now they're selling the exact same thing branded as Jubilance, for PMS symptoms, and benaGene, for just about everything under the Sun, including anti-aging, "brain fog", sugar cravings, and "stabiliz[ing] blood sugar levels".
They also make an eponymous oxaloacetate formula for Dr. Mitch Ghen D.O."Dr. Mitch’s Rock Solid Glucose" an oxaloacetate supplement made by Terra Biological LLC “Dr. Mitch” has twice been disciplined: once by the North Carolina Medical Board, and once by the Florida Board of Medicine.Mitchell Joseph Ghen, D.O., has been repeatedly disciplined, and investigated by the FDA. 
In their 2015 patent application, Terra Biological said that their oxaloacetate stuff is in clinical trials for "mitochondrial disease, Parkinson's disease, Alzheimer's disease and Cancer".Terra Biological's patent 2015 application. Is there nothing this miraculousTerra Biological do own a URL which has the word "miracle". substance can't treat?
The bulk price for oxaloacetate is US$1-$10 per kilogram.Bulk oxaloacetate is US$1-$10 per kilogram. CRONaxal could cost up to $1500 per month.The “highly aggressive package” of CRONaxal costs $1500 per month. A set of 12 benaGene bottles is, as of writing, on sale (better hurry up and buy!) for $499, which comes out to the low, low price of $13,861.11 per kilogram of oxaloacetate. Terra claims the oxaloacetate in their products is "thermally stabilized", although without giving any details on the method of doing so; you judge whether this justifies the rather large premium.
So benaGene/Jubilance/CRONaxal/Gilaxal allegedly treats many unrelated conditions, check ✔. It's recommended by dodgy doctors,CRONaxal is used at Hope4Cancer. check ✔. Its manufacturer uses the word "miracle", check ✔. It's sold as a food/supplement rather than a drug whose efficacy has to be proven, check ✔. Grossly overpriced, check ✔. All the hallmarks of a health-fraud scam.
==Science==
Anyone who knows their biochemistry rolled their eyes as soon as they saw "oxaloacetate". Oxaloacetate is literally everywhere in the human body, as it's an intermediate in several metabolic pathways, most notably the citric acid cycle, which takes place in every cell with mitochondria.That would be every cell in humans apart from red blood cells, which in mammals lose their organelles before being released into the blood. Oxaloacetate is found in detectable levels in the blood, and one study (actually using one of the Terra products) found no significant change in blood levels from a daily oral dose of 200 mg.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816034/This is unsurprising. is an issue for most things administered orally, and since oxaloacetate is already used in metabolic pathways, liver cells can easily consume it. Some of the studies Terra points to as showing possible benefits are animal studies that involved injection of high doses. It is possible that supraphysiological doses of oxaloacetate could do something in humans, but these doses might not be achievable orally, and in any case we need human studies to find out.
==Notes==
==External links==
* Another article which gives a decent overview, albeit coupled with ads for something else
* The CRONaxal website, which now redirects to benaGene
* Jubilance
* The CRONaxal label which states each capsule contains "Ascorbic Acid", (aka Vitamin C), & "Oxaloacetic Acid".
* YouTube videos by Terra Biological's "Chief Science Officer" & entrepreneur, Alan Cash. 
* Apparently Mr Cash's qualifications are in physical sciences, (rather than biology).
* A previous enterprise by Terra Biological's Allan Cash was "Terra-Kleen": a process to decontaminate polluted soil.
*Alan Cash "responsible for" an anti-aging oxaloacetate "formula" sold by Dave "Bulletproof" Asprey.
*Alan Cash has made a patent-application to use the oxaloacetate stuff as a "flavoring agent" for "chewing gum … confections, toothpaste … bottled water, frozen treats and the like."
* There is a 2005 patent-application by Alan Cash to use oxaloacetate as a hang-over treatment.
* Dr. Mitch Ghen's website — also offers colloidal silver, and pet products.
* Apparently Terra Biological's Alan Cash also has plans to offer pet products: for cats & dogs.
*Future products from Terra Biological apparently include "empathol", "plesurol", "pleasanol", "affectol", & "duzfukol".
* Dr Chris D. Meletis ND (a member of ), promotes CRONaxal.
*Dr. Kevin Bethel MD, (of the IAT clinic in the Bahamas), recommends CRONaxel, (and the RGCC test).
*CRONaxal is (or was) available at Dr Antonio Jimenez's Hope4Cancer clinics in Mexico.
* An Alan Cash presentation which includes Dr Gaston Cornu-Labat and Hope4Cancer's Dr Subrata Chakravarty.
==References==
Category:Alternative medicine
Category:Cancer woo