Peter Valent

Peter Valent (October 9 1962, Vienna, Austria) is an Austrian Hematologist and Stem Cell Researcher. Since 1990 he leads a research group at the Medical University of Vienna. 
== Life and education ==
Valent studied Medicine at the Medical University of Vienna and graduated in 1987. He is a specialist in Internal Medicine and Hematology and was promoted to Assistant Professor for Experimental Hematology in 1992 and Associate Professor for Internal Medicine in 1995. Valent visited several Universities in Germany as Guest Scientist, including the Institute of Pathology of the University of Tübingen, the University of Schleswig-Holstein (Campus Lübeck) and the LMU Munich.Peter Valent - Scientific CV, retrieved 13. March 2020 in Meduniwien.ac.at
== Scientific contributions ==
=== Contributions to Mast Cell Research and the Classification of Mastocytosis ===
Between 1989 und 1999 Valent examined the phenotype and growth characteristics of human mast cells. He found that mast cells form a unique lineage in the hematopoietic cell system. In subsequent studies, neoplastic mast cells were characterized.The riddle of the mast cell: kit(CD117)-ligand as the missing link?, retrieved 16. April 2020 in Europepmc.org The resulting data contributed essentially to the development of diagnostic criteria and the WHO classification of mastocytosis. In 2000, Valent organized a Working Conference on Mastocytosis to implement this classification together with an international consensus group.Classification and response criteria in mastocytosis: is there a need to revise?, retrieved 16. April 2020 in Expert Review of Hematology, Page 247 Since 2002 Valent coordinates the European Competence Network on Mastocytosis that expanded rapidly and provides a useful basis for the development and conduct of studies and activities in the field of mastocytosisEuropean Competence Network on Mastocytosis (ECNM): 10-year jubilee, update, and future perspectives, retrieved 15. April 2020 in Ncbi.nlm.nih.gov. In the forthcoming years, the diagnostic WHO criteria of mastocytosis were validated, adjusted and extended.Peter VALENT, MD, retrieved 8. April 2020 in Phd-mcca.at To discuss these developments, Valent and his team organized additional conferences in Vienna, including a Working Conference on Standards and Standardization of Diagnostic Criteria and Therapies in MastocytosisStandards and standardization in mastocytosis: Consensus Statements on Diagnostics, Treatment Recommendations and Response Criteria, retrieved 8. April 2020 in Onlinelibrary.wiley.com. and one on the Global Classification of Mast Cell Disorders and Mast Cell Activation Syndromes (2010)Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal, retrieved 8. April 2020 in Karger.com.
=== Additional scientific contributions ===
One additional focus in Valent´s research is the neoplastic stem cell, also termed cancer stem cell in the context of cancer and leukemic stem cell in leukemia contexts. Valent investigates the phenotype of these cells in various hematologic neoplasms and develops concepts predicting the step-wise development of these cells from normal stem cells. The major aim in his research is to identify molecular targets in these cells and to develop more effective (curative) therapies by eliminating these cells in various blood cell disorders, including Acute Myeloid Leukemia, Chronic Myeloid LeukemiaImmunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML, retrieved 15. April 2020 in Ncbi.nlm.nih.gov, Systemic MastocytosisHow I treat patients with advanced systemic mastocytosis, retrieved 15. April 2020 in Ncbi.nlm.nih.gov and Myelodysplastic SyndromesProposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions, retrieved 15. April 2020 in Ncbi.nlm.nih.gov. These studies are primarily conducted in the Ludwig Boltzmann Institute for Hematology and Oncology at the Medical University of Vienna.Professor Peter Valent, MD, retrieved 8. April 2020 in Cml-foundation.org
== Publications ==
Valent is member in a number of scientific societies and produced over 800 publications in his career, including more than 500 original articles, over 200 review articles and several chapters in world-leading text books in Hematology and Pathology.Peter Valent Publication list, retrieved 15. April 2020 in Publons.com In 2001, 2008 und 2016, he also served as author in the WHO Book chapter on mastocytosis.Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts, republished on 28. December 2016 in Ncbi.nlm.nih.gov Overall, his publications are cited over 30.000 times and his h-Index (based on Web of Science, March 2020) is 94.Peter Valent, retrieved 8. April 2020 in Publons.com
== Awards ==
Valent received several national and international awards, including the Karl Landsteiner-Award of the Austrian Society for Allergy and Immunology, the Paracelsus Award of the Austrian Society for Internal Medicine, the Wilhelm Türk Award of the Austrian Society for Hematology and Oncology, the Theodor-Billroth Medal of the Austrian Medical Association, the Mac Forster Award of the European Society for Clinical Investigation and the Middle European Award for Interdisciplinary Cancer Research.Univ.-Prof. Dr. Peter Valent, retrieved 8. April 2020 in Meduniwien.ac.at
==References==
==External links==
* Peter Valent's research works | Medical University of Vienna
* Peter VALENT, MD - MCCA PhD Program
* Profile_Peter Valent - The iCMLf | International CML ... - iCMLf
* Peter Valent, MD
* How I treat patients with advanced systemic mastocytosis
* Peter Valent - Elite Prospects
* Pr Peter VALENT - Orphanet
Category:1962 births
Category:Hematologists
Category:Austrian people
Category:Stem cell research
Category:Internal medicine
Category:Medical schools in Austria