Andre Nussenzweig

André Nussenzweig (born 25, October 1960, in São Paulo Brazil) is a molecular biologist (former physicist), Distinguished NIH investigator and Branch Chief of the Laboratory of Genome Integrity within the Center for Cancer Research at the National Cancer Institute. He is known for his contributions to understanding how cells prevent instability in their genome, which otherwise predisposes them to malignant transformation and cancer " [(https://ccr.cancer.gov/news/milestones-2021/article-repeated-mistakes-shattered-chromosomes]' " [(https://ccr.cancer.gov/news/article/study-reveals-regions-where-harmful-dna-breaks-are-most-likely-to-occur]' " [(https://ccr.cancer.gov/news/milestones-2018/article/opportunities-for-damage]' " [(https://ccr.cancer.gov/news/article/when-chemotherapy-interrupts-genetic-programs-critical-for-neuronal-development-and-activity-cells-accrue-dna-damage-and-die]'. 
==Research and career==
André Nussenzweig did his undergraduate studies in physics at New York University, and subsequently obtained a Ph.D. in physics at Yale University in 1989. He worked two years in the laboratory of Dr. Serge Haroche as a postdoctoral fellow at the Ecole Normale Superieure in Paris, France. He then became interested in a career in biological science, and in 1992, began research on DNA repair in the Department of Medical Physics at Memorial Sloan-Kettering Cancer Center. There, he established a long-standing collaboration with his brother Michel C. Nussenzweig at Rockefeller University working on immunoglobulin class-switch recombination. In 1998, he established his independent research group at the Experimental Immunology Branch at the National Cancer Institute at the National Institutes of Health in Bethesda Maryland. In 2011, he started his own department at the National Cancer Institute called the Laboratory of Genome Integrity. His research provides insight into various mutagenic sources, risk factors, and mechanisms underlying cancer " ' " '.
==Personal==
Nussenzweig lives in Washington DC and is an aspiring squash player. He is the youngest son of Victor and Ruth Nussenzweig who worked on the development of malaria vaccines " Love at first (insect) bite' " Ruth Nussenzweig Malaria Vaccine and Immunology Pioneer' " Fresh start, back in Brazil at 85' " Ruth Nussenzweig, Who Pursued Malaria Vaccine, Dies at 89' and brother of Michel C. Nussenzweig, an immunologist at Rockefeller University.
==Awards and Honors==
Nussenzweig is a recipient of numerous awards " ' including the Arthur S. Flemming Award (2007) " Arthur S. Flemming Awards', National Cancer Institute Director's Awards (2006, 2018, 2021); NIH Director's Awards (2006, 2014), Ellison Medical Foundation Senior Scholar in Aging (2011-2014), NIH Distinguished Investigator (2016), Long School of Medicine Distinguished Scholar Award (2021), and the Basser Global Prize for BRCA Research (2021) " 2021 Basser Global Prize' " '. He is on the Scientific Advisory Committee of Stand Up To Cancer.
In 2013, Nussenzweig was elected a member of European Molecular Biology Organisation (EMBO) " '. He is also an elected member of the National Academy of Medicine (2019) " 2019 National Academy of Medicine new members ', the American Academy of Arts and Science (2023) " 2023 American Academy of Arts and Sciences new members' " ' " ', and the National Academy of Sciences (2023) " 2023 National Academy of Science new member' " '. 
Category:1960 births
Category:People from São Paulo
Category:Brazilian people
Category:Yale University alumni
Category:New York University alumni
Category:Molecular biologists