Viridiflorol

==﻿Nom de la substance==
Viridiflorol
==Famille moléculaire==
Alcool sesquiterpénique
==Source végétale==
* Huile essentielle de niaouli, tea tree, cajeput, ciste labdanifère, sauges Salvia officinalis et Salvia sp, Vitex negundo, Helichrysum italicum, Allophylus edulis
==Propriétés==
* Inhibition de l'acétycholinestérase Mitsuo Miyazawa, Hitomi Watanabe, Kazuyasu Umemoto, Hiromu Kameoka. Inhibition of Acetylcholinesterase Activity by Essential Oils of Mentha Species. J. Agric. Food Chem., 1998, 46 (9), pp 3431–3434
* Inhibiteur de la formation de biofilms bactériens par Pseudomonas aeruginosa et Staphylococcus aureus Gilabert M, Marcinkevicius K2, Andujar S3, Schiavone M4, Arena ME5, Bardón A6. Sesqui- and triterpenoids from the liverwort Lepidozia chordulifera inhibitors of bacterial biofilm and elastase activity of human pathogenic bacteria. Phytomedicine. 2015 Jan 15;22(1):77-85. doi: 10.1016/j.phymed.2014.10.006. PMID 25636875
* Anti-inflammatoire, antioxydant, anti-tuberculeux in vitro Trevizan LNF, Nascimento KFD, Santos JA, Kassuya CAL, Cardoso CAL, Vieira MDC, Moreira FMF, Croda J, Formagio ASN. Anti-inflammatory, antioxidant and anti-Mycobacterium tuberculosis activity of viridiflorol: The major constituent of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk. J Ethnopharmacol. 2016 Nov 4;192:510-515. doi: 10.1016/j.jep.2016.08.053. PMID 27612433
* Promoteur d'absorption de l'estradiol Monti D, Tampucci S, Chetoni P, Burgalassi S, Bertoli A, Pistelli L. Niaouli oils from different sources: analysis and influence on cutaneous permeation of estradiol in vitro. Drug Deliv. 2009 Jul;16(5):237-42. doi: 10.1080/10717540902896297. PMID 19538003, Sapra B, Jain S, Tiwary AK. Percutaneous permeation enhancement by terpenes: mechanistic view. AAPS J. 2008;10(1):120-32. doi: 10.1208/s12248-008-9012-0. PMID 18446512, KALA Shivani, JUYAL Divya. RECENT DEVELOPMENTS ON NATURAL TRANSDERMAL PENETRATION ENHANCERS. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, vol. 9, no 6, p. 2190-2196., Monti D, Tampucci S, Chetoni P, Burgalassi S, Bertoli A, Pistelli L. Niaouli oils from different sources: analysis and influence on cutaneous permeation of estradiol in vitro. Drug Deliv. 2009 Jul;16(5):237-42. doi: 10.1080/10717540902896297. PMID 19538003
* Analogue de molécules œstrogéniques (comme le sclaréol et le trans-anéthole (?) Degrelle Margaux. Les hélichryses (ou immortelles) en aromathérapie : zoom sur l’Hélichryse italienne corse. Thèse Pharmacie, Université de Lorraine, avril 2015
==Effet thérapeutique==
* L'HE de niaouli peut être utilisée comme agent de blanchiment de la peau Chao WW, Su CC, Peng HY, Chou ST. Melaleuca quinquenervia essential oil inhibits α-melanocyte-stimulating hormone-induced melanin production and oxidative stress in B16 melanoma cells. Phytomedicine. 2017 Oct 15;34:191-201. doi: 10.1016/j.phymed.2017.08.024. PMID 28899502
==Effets indésirables==
==Bibliographie==
* Gbenou J. D, Moudachirou M, Chalchat Jean-Claude, Figueredo Gilles. Chemotypes in Melaleuca quinquenervia (Cav.) S.T. Blake (Niaouli) from benin using multivariate statistical analysis of their essential oils. The Journal of essential oil research, 2007, vol. 19, no2, pp. 101-104 
* J. P. Mariotti, F. Tomi, J. Casanova, J. Costa, A. F. Bernardini. Composition of the Essential Oil of Cistus ladaniferus L. Cultivated in Corsica (France). Flavour and Fragrance Journal, Volume 12, Issue 3, pages 147–151, May 1997 
* Genovaitė Bernotienė, Ona Nivinskienė, Rita Butkienė, Danutė Mockute. Essential oil composition variability in sage (Salvia officinalis L.). Chemija. 2007. Vol. 18. No. 4. P. 38–43
* Hala Gali-Muhtasib. Anticancer and medicinal properties of essential oil and extracts of East Mediterranean sage (salvia triloba). Advances in Phytomedicine, Volume 2, 2006, Pages 169–180
Catégorie:Principes actifs