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HemOnc.org - A Free Hematology/Oncology Reference
HemOnc.org is the largest freely available medical wiki of interventions, regimens, and general information relevant to the fields of hematology and oncology. Any healthcare professional can sign up to contribute; the accuracy and completeness of content is overseen by the Editorial Board. If this is your first time visiting, please start with the the tutorial page, review our philosophy, or just start exploring!
Regimens: 5,373	Guidelines: 1,217	Studies: 6,870	References: 7,919
Solid Tumors	Malignant Hematology	Pediatrics	Transplant & IEC	Classical Hematology
 
==Links to all main disease pages==
Solid Tumors 	Solid Tumors 	Solid Tumors 	Solid Tumors
Breast Oncology 	Breast Oncology 	Breast Oncology 	Breast Oncology
Breast cancer 	Breast cancer, ER-positive 	Breast cancer, HER2-positive 	Breast cancer, HER2-low New
Breast cancer, ER and HER2 co-expressing 	Breast cancer, triple negative (TNBC) 	Breast cancer, BRCA-mutated 	Breast cancer, PIK3CA-mutated
Dermatologic Oncology 	Dermatologic Oncology 	Dermatologic Oncology 	Dermatologic Oncology
Cutaneous BCC 	Cutaneous SCC 	Melanoma 	Melanoma, BRAF-mutated
Melanoma, KIT-mutated 	Melanoma, NRAS-mutated 	Merkel cell carcinoma (MCC) 	Uveal melanoma
Endocrine Oncology 	Endocrine Oncology 	Endocrine Oncology 	Endocrine Oncology
Adrenocortical carcinoma 	Neuroendocrine tumor (NET) 	Neuroendocrine carcinoma (NEC) 	Pancreatic NET
Pheochromocytoma 	Thyroid cancer 	Differentiated thyroid cancer (DTC) 	Medullary thyroid cancer (MTC)
Thyroid cancer, BRAF-mutated 	Thyroid cancer, RET-positive 	 	
Gastrointestinal Oncology, Intestinal 	Gastrointestinal Oncology, Intestinal 	Gastrointestinal Oncology, Intestinal 	Gastrointestinal Oncology, Intestinal
Anal cancer 	Appendiceal tumor 	Colon cancer 	Colon cancer, RAS wild-type
Colorectal cancer (CRC) 	CRC, BRAF-mutated 	CRC, HER2-positive 	CRC, MSI-H or dMMR
CRC, RAS wild-type 	Esophageal cancer 	Esophageal adenocarcinoma 	Esophageal SCC
Gastric cancer 	Gastric cancer, HER2-positive 	Rectal cancer 	Small bowel adenocarcinoma
Gastrointestinal Oncology, Extraintestinal	Gastrointestinal Oncology, Extraintestinal	Gastrointestinal Oncology, Extraintestinal 	Gastrointestinal Oncology, Extraintestinal
Cholangiocarcinoma 	Gallbladder cancer 	Hepatocellular carcinoma (HCC) 	Periampullary adenocarcinoma
Pancreatic adenocarcinoma 	Pancreatic adenocarcinoma, BRCA-mutated 	Pancreatic adenocarcinoma, NRG1-positive New	Pancreatic NET
Genitourinary Oncology 	Genitourinary Oncology 	Genitourinary Oncology 	Genitourinary Oncology
Penile cancer 	Prostate cancer 	Prostate cancer, HRD-positive 	Testicular cancer
Renal cell carcinoma (RCC) 	Clear cell RCC (ccRCC) 	Non-clear cell RCC (nccRCC) 	Papillary RCC
Sarcomatoid RCC 	VHL-associated RCC 	 	
Urothelial carcinoma 	Bladder cancer 	Upper tract urothelial carcinoma (UTUC) 	
Gynecologic Oncology 	Gynecologic Oncology 	Gynecologic Oncology 	Gynecologic Oncology
Cervical cancer 	Endometrial cancer 	Gestational trophoblastic neoplasia 	Low-grade serous ovarian cancer (LGSOC)
Ovarian cancer 	Ovarian cancer, BRCA-mutated 	Vulvar cancer 	
Head & Neck Oncology 	Head & Neck Oncology 	Head & Neck Oncology 	Head & Neck Oncology
Head and neck cancer 	Nasopharyngeal carcinoma (NPC) 	HPV+ Oropharyngeal cancer 	
Mesothelioma 	Mesothelioma 	Mesothelioma 	Mesothelioma
Malignant peritoneal mesothelioma (MPEM) 	Malignant peritoneal mesothelioma (MPEM) 	Malignant pleural mesothelioma (MPM) 	Malignant pleural mesothelioma (MPM)
Neuro-Oncology 	Neuro-Oncology 	Neuro-Oncology 	Neuro-Oncology
Anaplastic glioma 	Craniopharyngioma 	Glioblastoma (GBM) 	Low-grade glioma
Meningioma 	Subependymal giant cell astrocytoma (SEGA)	 	
CNS carcinoma 	CNS leukemia 	CNS lymphoma 	CNS melanoma
Sarcoma 	Sarcoma 	Sarcoma 	Sarcoma
Bone sarcoma 	Ewing sarcoma 	Giant-cell tumor of bone 	Osteosarcoma
Soft tissue sarcoma (STS) 	Alveolar soft part sarcoma (ASPS) 	Dermatofibrosarcoma protuberans 	Desmoid tumor
Epithelioid sarcoma 	Gastrointestinal stromal tumor (GIST) 	Inflammatory myofibroblastic tumor (IMT) 	Leiomyosarcoma (LMS)
Liposarcoma 	PEComa 	Rhabdomyosarcoma (RMS) 	Tenosynovial giant cell tumor (TGCT)
Vascular sarcoma 	Angiosarcoma 	Kaposi sarcoma (KS) 	
Thoracic Oncology 	Thoracic Oncology 	Thoracic Oncology 	Thoracic Oncology
Non-small cell lung cancer (NSCLC) 	NSCLC, nonsquamous 	NSCLC, squamous 	NSCLC, ALK-positive
NSCLC, BRAF-mutated 	NSCLC, EGFR-mutated 	NSCLC, HER2-mutated 	NSCLC, KRAS-mutated
NSCLC, MET-mutated 	NSCLC, NRG1-positive New 	NSCLC, RET-positive 	NSCLC, ROS1-positive
NSCLC, CNS metastases 	Small cell lung cancer (SCLC) 	Thymoma 	
Site-agnostic 	Site-agnostic 	Site-agnostic 	Site-agnostic
BRAF 	EGFR 	ERBB2 (HER2) 	ERBB3 (HER3)
MSI-H or dMMR 	NTRK 	RET 	SMO or PTCH-1 (Hedgehog)
TMB-H 	Carcinoma of unknown primary (CUP) 	 	
Malignant Hematology 	Malignant Hematology 	Malignant Hematology 	Malignant Hematology
Acute leukemias 	Acute leukemias 	Acute leukemias 	Acute leukemias
Acute myeloid leukemia (AML) 	AML, FLT3-positive 	AML, IDH-mutated 	AML, NPM1-mutated
Acute promyelocytic leukemia (APL) 	B-cell acute lymphoblastic leukemia (B-ALL) 	B-ALL, Ph+ 	T-cell acute lymphoblastic leukemia (T-ALL)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) 	CNS leukemia 	 	
Myeloproliferative neoplasms and myelodysplastic syndromes	Myeloproliferative neoplasms and myelodysplastic syndromes	Myeloproliferative neoplasms and myelodysplastic syndromes	Myeloproliferative neoplasms and myelodysplastic syndromes
Chronic myeloid leukemia (CML) 	Chronic myelomonocytic leukemia (CMML) 	Essential thrombocythemia (ET) 	Hypereosinophilic syndrome (HES)
Myelodysplastic syndrome (MDS) 	Primary & secondary myelofibrosis 	Polycythemia vera (PV) 	Systemic mastocytosis
Aggressive lymphomas 	Aggressive lymphomas 	Aggressive lymphomas 	Aggressive lymphomas
Burkitt lymphoma (BL) or Burkitt-like lymphoma 	Classical Hodgkin lymphoma (cHL) 	CNS lymphoma 	Diffuse large B-cell lymphoma (DLBCL)
High-grade B-cell lymphoma 	HIV-associated lymphoma 	Mantle cell lymphoma (MCL) 	Mediastinal gray-zone lymphoma (MGZL)
Primary mediastinal B-cell lymphoma (PMBL) 	Transformed lymphoma (TL) 	 	
Indolent lymphomas 	Indolent lymphomas 	Indolent lymphomas 	Indolent lymphomas
Chronic lymphocytic leukemia (CLL/SLL) 	Follicular lymphoma (FL) 	Hairy cell leukemia (HCL) 	Hodgkin lymphoma, nodular lymphocyte-predominant (NLP-HL)
MALT lymphoma 	Marginal zone lymphoma (MZL) 	Waldenström macroglobulinemia (WM/LPL) 	
Plasma cell dyscrasias 	Plasma cell dyscrasias 	Plasma cell dyscrasias 	Plasma cell dyscrasias
Light-chain (AL) amyloidosis 	Multiple myeloma (main page) 	MM, induction 	MM, consolidation & maintenance
MM, relapsed/refractory 	Plasma cell leukemia (PCL) 	POEMS syndrome 	Smoldering multiple myeloma (SMM)
T-cell and NK-cell neoplasms 	T-cell and NK-cell neoplasms 	T-cell and NK-cell neoplasms 	T-cell and NK-cell neoplasms
Adult T-cell leukemia-lymphoma (ATLL) 	Anaplastic large cell lymphoma (ALCL) 	Cutaneous T-cell lymphoma (CTCL) 	Extranodal NK- and T-cell lymphoma, nasal type (ENKTCL-NT
Large granular lymphocytic (LGL) leukemia 	NK- and T-cell lymphoma (NKTCL) 	Peripheral T-cell Lymphoma (PTCL) 	T-cell acute lymphoblastic lymphoma (T-LBL)
T-cell prolymphocytic lymphoma (T-PLL) 	 	 	
Lymphoproliferative disorders 	Lymphoproliferative disorders 	Lymphoproliferative disorders 	Lymphoproliferative disorders
Castleman disease 	Castleman disease 	Post-transplant lymphoproliferative disorder (PTLD) 	Post-transplant lymphoproliferative disorder (PTLD)
Histiocytic disorders 	Histiocytic disorders 	Histiocytic disorders 	Histiocytic disorders
Erdheim-Chester disease (ECD) 	Hemophagocytic lymphohistiocytosis (HLH) 	Langerhans cell histiocytosis (LCH) 	Rosai-Dorfman-Destombes disease
Pediatric Neoplasms 	Pediatric Neoplasms 	Pediatric Neoplasms 	Pediatric Neoplasms
Pediatric CNS malignancies 	Pediatric CNS malignancies 	Pediatric CNS malignancies 	Pediatric CNS malignancies
Low-grade glioma 	High-grade glioma 	Medulloblastoma 	
Pediatric hematologic neoplasms 	Pediatric hematologic neoplasms	Pediatric hematologic neoplasms 	Pediatric hematologic neoplasms
B-cell acute lymphoblastic leukemia (B-ALL)	B-ALL, Ph+ 	T-cell acute lymphoblastic leukemia (T-ALL)	Acute myeloid leukemia (AML)
Anaplastic large cell lymphoma (ALCL) 	Chronic myeloid leukemia (CML) 	Juvenile myelomonocytic leukemia (JMML) 	
Classical Hodgkin lymphoma (cHL) 	Non-Hodgkin lymphoma (NHL) 	 	
Pediatric solid tumors 	Pediatric solid tumors 	Pediatric solid tumors 	Pediatric solid tumors
Epithelioid sarcoma 	Ewing sarcoma 	Hepatoblastoma 	Neuroblastoma
Osteosarcoma 	Retinoblastoma 	Rhabdomyosarcoma 	Wilms tumor
Transplant and Immune Effector Cells (IECs)	Transplant and Immune Effector Cells (IECs)	Transplant and Immune Effector Cells (IECs)	Transplant and Immune Effector Cells (IECs)
Stem cell mobilization 	Allogeneic HSCT 	Autologous HSCT 	Chimeric antigen receptor T cells (CAR-T)
Graft versus host disease (GVHD) 	Hepatic veno-occlusive disease (VOD/SOS) 	 	
Classical Hematology 	Classical Hematology 	Classical Hematology 	Classical Hematology
Hemostasis and thrombosis 	Hemostasis and thrombosis 	Hemostasis and thrombosis 	Hemostasis and thrombosis
Acquired coagulopathy 	Acquired thrombotic thrombocytopenic purpura (aTTP)	Antiphospholipid antibody syndrome (APLAS)	Congenital thrombotic thrombocytopenic purpura (cTTP)
Heparin-induced thrombocytopenia (HIT) 	Hereditary hemorrhagic telangiectasia (HHT) 	Inherited coagulopathy 	Inherited thrombophilia
Thrombotic microangiopathy (TMA) 	Venous thromboembolism (VTE) 	 	
Cytopenias 	Cytopenias 	Cytopenias 	Cytopenias
Aplastic anemia 	Autoimmune cytopenia 	Immune thrombocytopenia (ITP) 	Thrombocytopenia in liver disease
WHIM syndrome 	 	 	
Hemolytic disorders and Hemoglobinopathies	Hemolytic disorders and Hemoglobinopathies 	Hemolytic disorders and Hemoglobinopathies	Hemolytic disorders and Hemoglobinopathies
Atypical hemolytic uremic syndrome (aHUS) 	Warm autoimmune hemolytic anemia (WAIHA) 	Cold agglutinin disease (CAD) 	Paroxysmal nocturnal hemoglobinuria (PNH)
Pyruvate kinase deficiency (PKD) 	Beta thalassemia 	Sickle cell anemia 	
Browse our complete index of pages
==Additional Information==
Created as a knowledge base for hematology & oncology providers, HemOnc.org is a collaborative wiki containing details about hundreds of hematology/oncology drugs, and thousands of treatment regimens. Content is added by hematology & oncology professionals, and undergoes continuous peer review.
Any information that one feels would be helpful to other oncology providers is welcome. Visit how to contribute for more details.
Priorities of this project include:
*Creating a database of all approved systemic anticancer therapy agents and supportive medications used in the field of hematology/oncology.
*Creating a database of all standard-of-care systemic anticancer therapy regimens and references to primary literature.
*Sample order sets and examples of supportive medications used with treatment regimens
*Aggregating useful links to existing resources by disease, such as guidelines, information about prognosis, clinical calculators, staging, and patient resources.
*Creating, maintaining, and disseminating a formalized ontology of anticancer drugs and regimens.
Additional possibilities for this project may include:
*Creating synopses of pivotal clinical trials and regimens
*Prioritizing regimens by their efficacy and/or toxicity
*Capturing historical regimens that were standard-of-care prior to 2005
*Checklists for common clinical scenarios/diseases
*Creating checklists that can be used for patients starting therapy with particular regimens, such as laboratory & imaging (e.g. echocardiogram, PFTs) parameters to monitor and informed consent/discussion of side effects
The field of hematology/oncology is ever-changing, and our hope is that other people will be interested in contributing to make it an increasingly more useful resource. The rapidly evolving nature of the practice demands a more dynamic medium than existing resources can provide and would benefit from being able to be updated in real-time from virtually any computer with internet access. We believe that the familiar format of a Wiki, made popular by sites such as Wikipedia, will significantly help ease-of-use and navigation.
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