List of permanently missable items

This is a list of items in the Pokémon games that can be permanently missed.
This page does not include items that are missed by choosing another item (such as mutually exclusive Fossils), items missable due to exploiting glitches, nor event items. Furthermore, items that can no longer be obtained after the internal battery of Pokémon Ruby, Sapphire, or runs dry are also excluded.
==In the core series games==
===Kanto===
====Professor Oak's Laboratory====
In the Generation I and games, five s can be obtained from Professor Oak after defeating the on if the has no Poké Balls in the bag and has added no caught data to the Pokédex aside from first partner Pokémon.
====S.S. Anne====
=====Port=====
This item can only be obtained if is used while the S.S. Anne is still in . Once the S.S. Anne leaves, the cannot access the area in which Surf must be used again.
=====Ship=====
In the Generation I games, , Let's Go, Pikachu!, and Let's Go, Eevee! after obtaining /learning Chop Down and leaving the S.S. Anne, it sets sail.
In the Generation I games, exploiting a glitch can allow the player to board the S.S. Anne after it has left. In Pokémon: Let's Go, Pikachu! and Let's Go, Eevee!, the player can receive extra s for defeating the Trainers on the ship, but if the player doesn't battle a Trainer before learning the Secret Technique from the captain, that Trainer will act as if already defeated and cannot be battled.
 
====Silph Co.====
In Pokémon: Let's Go, Pikachu! and Let's Go, Eevee!, if the player hasn't defeated Dalton before defeating Giovanni at the top floor of the Silph Co., he will disappear from the building, along with the rest of the Trainers associated with Team Rocket, and the three s he hands out upon being beaten become unobtainable.
===Johto===
====Mahogany Town====
In the Generation II games, the Slowpoke Tail can be bought for 9800 in prior to speaking to Lance at the Lake of Rage. Once Lance opens the secret entrance to the Team Rocket HQ, the salesman no longer sells anything, and once the player has cleared the HQ, the Slowpoke Tail is not a part of the new merchant's selection of buyable items. The tail isn't available for sale at the shop at any point during , even though it exists in the game's coding.
===Hoenn===
====Trick House====
After clearing a room, the Trick Master rebuilds the puzzle room into the next one. After clearing the final room, the Trick Master leaves and the player cannot access the puzzle room anymore.
====Magma and Aqua Hideouts====
In , the entrance to the Magma Hideout or the Aqua Hideout is sealed after defeating Tate and Liza. 
====Sky Pillar====
In , when has appeared and wants to battle the player, Zinnia will give the player an Ultra Ball if they have no Poké Balls (of any kind) in their Bag.
===Sinnoh===
====Lake Valor====
In Pokémon Diamond, Pearl, , Brilliant Diamond, and Shining Pearl, Lake Valor is initially drained by a Galactic Bomb, allowing the player to walk across the lakebed. After , , or has been caught or defeated, the lake is refilled and the player can no longer access the HP Up on the lakebed.
===Unova===
====N's Castle====
In , the player cannot access N's Castle after defeating Ghetsis.
===Alola===
====Altar of the Sunne/Moone====
In , when battling / at the Altar of the Sunne/Altar of the Moone, if the player has no Poké Balls (of any kind) in their Bag after defeating or running from Solgaleo/Lunala, Lillie will give the player 10 standard Poké Balls.
===Galar===
====Motostoke====
In , the player can accept a request from a boy near the northwest Pokémon Center to find a lost . If the player heads to Motostoke Stadium and checks around the fountain to the right of the building, they will find a man who will give them a Fresh Water. Once the Minccino is found and returned, the player is unable to obtain the Fresh Water.
==In the side series games==
===Pokémon XD: Gale of Darkness===
====ONBS====
At ONBS, if the player returns a girl named Kandee on 2F to her mother on 3F before Cipher invades the building, they will receive a Soothe Bell from her mother. If the invasion has already happened, Kandee will have already been reunited with her mother and the Soothe Bell cannot be obtained. This is the only way to obtain a Soothe Bell in Pokémon XD: Gale of Darkness without trading.
====Trainers' Pokémon's held items====
In Pokémon XD: Gale of Darkness, during the post-game battle with Eagun at the Pokémon HQ Lab, both of his are each holding a Light Ball. Eagun cannot be rematched, so if it they are not stolen with , , or when he is battled, it is impossible to obtain them later. This is the only way to obtain a Light Ball in Pokémon XD: Gale of Darkness without trading.
==In the spin-off games==
===Trading Card Game series===
In , a Lad in the west room of the Fire Club asks the player to give him all his unused . If the player complies, he receives a Slowpoke card. If the player refuses, the Lad goes away without giving him the Slowpoke card.
In Pokémon Trading Card Game 2: The Invasion of Team GR!, it is possible to delete mail from the Minicom without reading it or getting any attached . The mail and attached booster packs cannot be recovered if deleted.
==Related articles==
* List of permanently missable Pokémon
Category:Lists of items
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