Non-Darwinian evolution

Non-Darwinian evolution is any mechanism which tends to downplay the role of natural selection in evolution. It also may reject gradualism, sexual selection or any other aspect of Darwinian evolution. 
It should be remembered that "alternative medicine" which actually works is called "medicine". The same care needs to be taken with "Non-Darwinian evolution" — if it were generally accepted it would be part of the Modern Synthesis.
==Introduction==
Historian of science Peter J. Bowler has written on non-Darwinian evolution in detail. According to Bowler, non-Darwinian theories of evolution were widely accepted in the late 19th century and focused attention on conceptual issues that have now been reopened by evolutionary developmental biology. Non-Darwinian evolution was proposed because many scientists did not believe natural selection was powerful enough to explain evolution.Do we need a non-Darwinian industry? by Peter J. Bowler (2009) Notes Rec. R. Soc. 63:393–398. doi:10.1098/rsnr.2009.0008.
Bowler, who has written The Eclipse of Darwinism: anti-Darwinian evolutionary theories in the decades around 1900 (1983), has described a period called the eclipse of Darwinism which discusses the state of affairs prior to the neo-Darwinian synthesis, when evolution was widely accepted in scientific circles, but relatively few biologists believed that natural selection was its primary mechanism. Instead of natural selection, scientists in this period were advocating other non-Darwinian mechanisms, such as orthogenesis, neo-Lamarckism, vitalism, or saltationism. Most scientists of this period did not deny natural selection, they just said it either has no role in evolution or only has a minor role as a mechanism.
Some of the non-Darwinian theories of the later 19th century, such as theistic evolution and orthogenesis, were often progressionist and implicitly teleological: they assumed that evolution was intended to develop toward a directed path or trend.Evolution: The History of an Idea by Peter Bowler (1989) University of California Press. ISBN 0520261283.
The non-Darwinian alternative mechanisms, such as saltationism and neo-Lamarckism, had a significant following well into the 20th century and it wasn't until developments in genetics made some of them less popular. They were largely abandoned when population genetics and the modern evolutionary synthesis demonstrated the explanatory power of natural selection. wrote that as late as 1930, most textbooks still emphasized non-Darwinian mechanisms of evolution.The Evolutionary Synthesis: Perspectives on the Unification of Biology, edited by Ernst Mayr & W. B. Provine (1998) Harvard University Press. ISBN 0674272269.
==Definition==
Non-Darwinian evolution does not deny or dispute common descent or the fact of evolution. It is only concerned with denying or downplaying the "Darwinian" mechanisms of evolution, such as natural selection or sexual selection. In the early 1900s, there was a near-universal tendency to accept evolution while rejecting Darwin's central premise: natural selection. Genetic engineering may place the selection power in the boardroom, as in the case of the designer organisms proposed by transhumanists. Most non-Darwinian evolutionary mechanisms also deny gradualism.
All genetic mechanisms, such as gene flow, mutation, genetic drift or genetic hitchhiking could be considered "non-Darwinian", because Charles Darwin did not know about genetics. However, scientists who advocate the neo-Darwinian synthesis have reconciled all of these genetic mechanisms with natural selection within a Darwinian framework. Non-Darwinian evolution is in opposition to the neo-Darwinian synthesis, which ascribes a central role to natural selection. Non-Darwinian evolutionary scientists such as (Shapiro, 2011) deny that genetic mechanisms can fit into a Darwinian framework (see below). 
===Macroevolution and speciation===
In the "modern synthesis" of neo-Darwinism, which developed in the period from 1930 to 1950 as a result of reconciliation of evolution by natural selection with genetics, macroevolution is defined as the combined effects of microevolutionary processes. Non-Darwinians, who proposed orthogenetic mechanisms, claimed that macroevolution is a different process than microevolution. According to biologist John Wilkins, nobody has been able to make a good case for orthogenesis since the 1950s. Wilkins also wrote that "Non-Darwinian evolutionists think that the processes that cause speciation are of a different kind to those that occur within species. That is, they admit that macroevolution occurs, but think that normal genetic change is restricted by such proposed mechanisms as developmental constraints. This view is associated with the names of and Waddington, who were often characterised as being non-Darwinians by the modern synthesis theorists."Macroevolution by John Wilkins (1997) The Talk Origins Archive (archived from September 19, 2002).Macroevolution (01-04-2007 01:16:19) Chemistry Daily: The Chemistry Encyclopedia (archived from October 31, 2012). "A few non-Darwinian evolutionists remained, however, including Schmalhausen and Waddington, who argued that the processes of macroevolution are different from those of microevolution. According to these scientists, macroevolution occurs, but is restricted by such proposed mechanisms as developmental constraints. The concept can be summarized in: "Schmalhausen's Law," which holds that "When organisms are living within their normal range of environment, perturbations in the conditions of life and most genetic differences between individuals have little or no effect on their manifest physiology and development, but that under severe and unusual general stress conditions even small environmental and genetic differences have major effects." Non-Darwinian evolution points to evidence of great changes in population under conditions of stress; however, it is generally rejected by the scientific community because it provides no mechanism for larger changes at a genetic level under those circumstances."
==Mechanisms==
The most well known non-Darwinian mechanisms include:So You Want to be an Anti-Darwinian: Varieties of Opposition to Darwinism by John Wilkins (December 21, 1998) The Talk Origins Archive.
*Orthogenesis — the view that evolution proceeds along predetermined paths rather than through selection from a pool of random change, also sometimes called teleological evolution or progressionism
*Neo-Lamarckism — the view that the environment instructs the genome, and/or the view that changes occur to anticipate the needs of the organism
*Process Structuralism — the view that there are deep laws of change that determine some or all of the features of organisms
*Saltationism — the view that major changes between forms occur all-at-once or not at all, opposes Darwinian gradualism
American biologist James A. Shapiro described the following non-Darwinian mechanisms.Revisiting Evolution in the 21st Century by James A. Shapiro (October 3, 2010) Department of Biochemistry and Molecular BiologyUniversity of Chicago.
* (1861-1926) and (1848-1935): abrupt variation as a source of evolutionary novelty.
*Richard Goldschmidt (1878-1958): altering developmental processes as a source of rapid evolutionary novelty (“hopeful monsters” and Evo-Devo).
* (1902-1992): genetic change as a biological response to danger and evolutionary novelty through genome restructuring resulting from "shocks".
* (1906-2000): hybridization between species as a source of evolutionary novelty.
* (1928-2012): molecular phylogeny and the existence of at least three distinct cell kingdoms.
* (1938-2011): cell mergers/symbiogenesis as a source of evolutionary novelty.
==Orthogenesis==
Orthogenesis, also known as directed evolution, is the hypothesis that evolution has an innate tendency to evolve in an unilinear fashion due to some internal or external force or mechanism. Various theories of orthogenesis were presented in the 20th century by many scientists such as apogenesis (Hans Przibram), allelogenesis (Alphonse Labbé), bathmism (Edward Drinker Cope) nomogenesis (Lev Berg), aristogenesis (Henry Fairfield Osbourn), hologenesis (Daniel Rosa), Omega Point (Pierre Teilhard de Chardin) and typostrophism (Otto Schindewolf).The Persistence of Heresy: The Concepts of Directed Evolution (Orthogenesis) by Igor Popov (Apr 07, 2005 | 13:15) KLI Colloquium (archived from April 15, 2015).
The theories of orthogenesis ranged from mystical forces to mechanical processes. Most however who subscribed to orthogenesis hypothesized some physical rather than metaphysical determinant of orderly change. In 1930 the American zoologist Austin Hobart Clark attempted to modify orthogenesis with his theory of zoogenesis.
The orthogenesis hypothesis began to collapse after it was discovered it could not explain some of the patterns found by paleontologists in the fossil record, which were non-linear with many complications. Orthogenesis was abandoned by most scientists due to the discovery of genetic mechanisms of evolution in the 20th century.The Eclipse of Darwinism: Anti-Darwinian Evolution Theories in the Decades around 1900 by Peter J. Bowler (1983) Johns Hopkins University Press. ISBN 0801829321
===Current status===
Orthogenesis is considered obsolete by most scientists since the 1950s. Antonio Lima-de-Faria, a cytogeneticist, has recently defended a form of directed evolution in his publications, writing that evolution is "ordered" by physico-chemical processes and that natural selection has nothing to do with evolution.The Problem of Constraints on Variation, From Darwin to the Present by Igor Popov (2009) Ludus Vitalis XVII(32):201-220 (archived from June 14, 2011). His views have been criticised by other scientists.Evolution without Selection: Form and Function by Autoevolution, a Review by Gert Korthof (16 Jan 2001; update 23 Apr 2011) Towards The Third Evolutionary Synthesis.
==Neo-Lamarckism==
The term neo-Lamarckism refers to a loose grouping of largely heterodox theories and mechanisms that emerged after Lamarck's time which support the inheritance of acquired characteristics (physiological changes acquired over the life of an organism transmitted to offspring). 
According to Peter J. Bowler:
 
Lamarckian evolution fell into decline due to the experimental work of the German biologist August Weismann, which resulted in the germplasm theory of inheritance, according to which (in a multicellular organism) inheritance only takes place by means of the germ cells—the gametes such as egg cells and sperm cells. Other cells of the body—somatic cells—do not function as agents of heredity. The effect is one-way: germ cells produce somatic cells and are not affected by anything the somatic cells learn or therefore any ability the body acquires during its life. Genetic information cannot pass from soma to the germplasm and on to the next generation. This is referred to as the Weismann barrier and if true, rules out the inheritance of acquired characteristics as proposed by Lamarck.
The ideas of Weismann were believed to be true by many scientists. One of his experiments involved cutting the tails off many generations of mice and found that their offspring continued to develop tails. Despite these criticisms, neo-Lamarckism remained the most popular alternative to natural selection at the end of the 19th century, and would remain the position of some naturalists in the 20th century. Due to the rise of Mendelian genetics in 20th century the possibility of acquired characteristics was denied by the neo-Darwinian synthesis. 
The paleontologist Edward Drinker Cope (1840–1897) was the main advocate of neo-lamarckism in America. Other notable supporters included Samuel Butler (1835-1902), George Bernard Shaw (1856-1950) and Arthur Koestler (1905-1983). Neo-Lamarckism remained popular in France as late as the 1980s due to scientists such as Albert Vandel (1894-1980) and Pierre-Paul Grassé (1895-1985).French roots of French neo-lamarckisms, 1879-1985 by Laurent Loison (2011) J. Hist. Biol. 44(4):713-44. doi:10.1007/s10739-010-9240-x.
Lysenkoism was a notable form of neo-Lamarckism in the Soviet Union. In the early to mid-20th century, agronomist Trofim Denisovich Lysenko (1898-1976) developed theories about evolution that rejected Darwin's and Mendel's work and instead adopted a form of Lamarckism that was interested particularly in vernalization and hybridization.Lysenkoism Against Genetics: The Meeting of the Lenin All-Union Academy of Agricultural Sciences of August 1948, Its Background, Causes, and Aftermath by Svetlana A. Borinskayaet al. (2019) Genetics 212(1):1–12. doi:10.1534/genetics.118.301413. The term "Lysenkoism" typically does not refer to Lysenko's theories, but rather his political tactics. Lysenko successfully convinced the government to integrate his ideas into their agricultural development, rejecting the "bourgeois pseudoscience" of genetics, and framed his theories as dialectical, and therefore Marxist, in nature.The Disastrous Effects of Lysenkoism on Soviet Agriculture by K. Lee Lerner (2019) Encyclopedia.com.
 
===Current status===
Despite the abandonment by most scientists, interest in Lamarckism has recently increased due to discoveries and studies in epigenetics.Early 20th Century Evolutionist May Have Discovered Epigenetics (September 3, 2009) Science Daily. In MIT's Technology Review in February 2009, it was written "The effects of an animal's environment during adolescence can be passed down to future offspring ... The findings provide support for a 200-year-old theory of evolution that has been largely dismissed: Lamarckian evolution, which states that acquired characteristics can be passed on to offspring."A Comeback for Lamarckian Evolution? Two new studies show that the effects of a mother’s early environment can be passed on to the next generation. by Emily Singer (February 4, 2009) MIT Technology Review (archived from 3 Feb 2013 12:43:28 UTC).
==Process Structuralism==
Process structuralism is a school of biological thought that deals with the law-like behaviour of the structure of organisms and how it can change. Structuralists tend to emphasise that organisms are wholes, and that change in one part must necessarily take into account the inter-connected nature of the entire organism.”Beyond the Darwinian Paradigm: Understanding Biological Forms” by Brian Goodwin In: Evolution: The First Four Billion Years, edited by Michael Ruse & Joseph Travis (2009) Harvard University Press. An early advocate of structuralism was D'Arcy Wentworth Thompson author of On Growth and Form (1917).
On the subject of process structuralism (Griffiths, 2006) has written "[Structuralists] downplay the role of natural selection in explaining the diversity of life. They interpret evolutionary history as an exploration of possibilities implicit in the conditions that set up the evolutionary process. According to process structuralists... the space of possible biological forms ('morphospace') is divided into regions characterized by particular 'generic forms'. From a Darwinian perspective, generic forms appear as traits that are highly conserved in certain lineages. According to process structuralism, generic forms result from the fundamental ways in which organisms in those lineages grow."Darwinism, Process Structuralism, and Natural Kinds by Paul E. Griffiths (1996) Philosophy of Science 63 (Proceedings):S1-S9 (archived from July 17, 2011). In process structuralism genes cannot fully explain the complexity of biological systems. 
According to the process structuralist critique of neo-Darwinism:The rebirth of rational morphology by David Resnik 
# There are general laws in biology and that biologists should search for these laws.
# There are general forms of morphology and development and that biologists should attempt to uncover these forms.
# Organisms are unified wholes that cannot be understood without adopting a holistic perspective.
# No special, causal primacy should be given to the genes in development and morphology.
The research of the Canadian biologist Brian Goodwin (1931-2009) is known for having laid the foundations for the process structuralist movement in biology.Tribute to Brian Goodwin 1931-2009
===Current status===
Process structuralism is not a mainstream school of biological thought and has been criticised by some scientists, however some biological structuralist ideas have been taken up by evolutionary developmental biology.
==Saltationism==
Saltationism is defined as a sudden change from one generation to the next, that is large, or very large, in comparison with the usual variation of an organism. Saltational evolution is non-gradual and violates the standard concepts of gradualism in evolution. 
Prior to Charles Darwin virtually all evolutionary scientists had been saltationists.Osborn, H. F. 1894. From the Greeks to Darwin: An outline of the development of the evolution idea. New York, London, Macmillan and Co. With the publication of On Origin of Species in 1859 Darwin had denied saltational evolution by writing that evolutionary transformation always proceeds gradually and never in jumps. Darwin insisted on slow accumulation of small steps in evolution and wrote "natural selection acts solely by accumulating slight successive favourable variations, it can produce no great or sudden modification; it can act only by very short steps".Origin, P. 471 Darwin had a strong belief in gradualism due to his observations on the Galápagos Mockingbird which were best explained by gradual evolution. Darwin was also influenced by Charles Lyell's uniformitarianism.
Darwin's friend Thomas Henry Huxley felt that evolution could be either gradual or saltational. In his review of the Origin he wrote:
Other scientists of this era similar to Huxley also held the view that evolution could be both gradual or saltational. It wasn't until the discovery of genetics in the 1890s that saltationism came to be known as the idea that new species arise as a result of large mutations. It was seen as faster alternative to the Darwinian concept of a gradual process of small random variations being acted on by natural selection. The view was popular with early geneticists such as and Thomas Hunt Morgan.Bowler, Peter J. (1983). The Eclipse of Darwinism: anti-Darwinian evolutionary theories in the decades around 1900. Johns Hopkins University Press. This mutation theory of evolution held that species went through periods of rapid mutation, possibly as a result of environmental stress, that could produce multiple mutations, and in some cases completely new species, in a single generation. This mutationist view of evolution was later replaced by the reconciliation of Mendelian genetics with natural selection into a gradualistic framework for the neo-Darwinian synthesis.Bowler, Peter J. (2003). Evolution:The History of an Idea. University of California Press.
It was the emergence of population thinking in evolution which forced many scientists to adopt gradualism in the early 20th century. According to Ernst Mayr, it wasn't until the development of population genetics in the neo-Darwinian synthesis in the 1940s that demonstrated the explanatory power of natural selection that saltational views of evolution were largely abandoned.Ernst Mayr What Makes Biology Unique?: Considerations on the Autonomy of a Scientific Discipline Cambridge University Press; 1 edition 2007 
Some of the last supporters of saltational evolution by large mutations were Richard Goldschmidt, who is most well known for his hypothesis of hopeful monsters, Otto Schindewolf and J. C. Willis.
===Current status===
Exceptions to gradualism include cases of stabilized hybrids that can reproduce without crossing (such as allotetraploids) and cases of Polyploidy (most common in plants but also in some animals) is also considered a type of saltation. Evidence of phenotypic saltation has been found in the centipedeSaltational evolution of trunk segment number in centipedes by Alessandro Minelli et al. (2009) Evolution & Development 11(3):318–322. doi:0.1111/j.1525-142X.2009.00334.x. and some scientists have suggested there is evidence for independent instances of saltational evolution in Sphinx Moths.Evidence of Repeated and Independent Saltational Evolution in a Peculiar Genus of Sphinx Moths (Proserpinus: Sphingidae) by Daniel Rubinoff (December 24, 2008) Plos One doi:10.1371/journal.pone.0004035. Some processes of epigenetic inheritance can also produce changes that are saltational.Epigenetic inheritance and plasticity: The responsive germline by Eva Jablonka (2013) Prog. Biophys. Mol. Biol. 111(2-3):99-107. doi:10.1016/j.pbiomolbio.2012.08.014. There has been a controversy over if mimicry in butterflies and other insects can be explained by gradual or saltational evolution.Mimicry, Saltational Evolution, and the Crossing of Fitness Valleys by Olof Leimar et al. (2012) In: The Adaptive Landscape in Evolutionary Biology, edited by E. I> Svensson & R. Calsbeck. ISBN 0199595372. pp. 259-270. According to Norrström et al., there is evidence for saltation in some cases of mimicry.Coevolution of exploiter specialization and victim mimicry can be cyclic and saltational by Niclas Norrström et al. (2006) Evolutionary Bioinformatics Online 2:35-43.
Eugene K. Balon has recently advocated some controversial mechanisms of saltation due to his research in ichthyology but have been criticised by some scientists.
==Controversies==
===Punctuated equilibrium===
Punctuated equilibrium is a theory in evolutionary biology which proposes that most species will exhibit little net evolutionary change for most of their geological history, remaining in stasis. Whilst significant evolutionary change occurs, the theory proposes that it is generally restricted to rare and geologically rapid events of branching speciation. It is commonly contrasted against the theory of phyletic gradualism. Paleotonologists such as Stephen Jay Gould, Niles Eldredge and Steven M. Stanley have advocated punctuated equilibrium and have explained how it is still compatible with the neo-Darwinian synthesis via an extension. Gould, Eldredge and Stanley have all called for an extended evolutionary synthesis. Creationists usually claim that Gould, Eldredge and Stanley are "anti-Darwinians," but this is not true since they all accepted natural selection. 
The biologist Soren Lovtrup wrote that punctuated equilibrium is not a non-Darwinian theory as it can still be classified as a form of gradualism.Neo-darwinism: an emperor with no clothes. Review of: Darwinism: The Refutation of a Myth by Søren Løtrup & Croom Helm by David Lambert (October 15, 1988) New Scientist. Punctuated equilibrium should not be confused with saltationism.
===Directed mutation===
Directed mutation is the hypothesis that organisms can respond to environmental stresses through directing mutations to certain genes or areas of the genome. Most experiments have proven mutations are random, so the idea of directed mutation is rejected by many scientists. There is still a controversy over the work of John Cairns on supposed evidence for directed mutation in bacteria which he later termed "adaptive evolution" which some scientists have rejected, instead proposing his results can be explained by Darwinian processes.
===Extinctions===
In the classical Darwinian view of evolution, extinctions are seen as the consequence of natural selection. David Raup, author of Extinction. Bad Genes or Bad Luck? (1991), does not deny that some species go extinct this way but has written that the majority of extinctions especially mass extinctions are caused by physical factors such as comets, climatic changes and catastrophes. and Steven M. Stanley have also written on extinctions and advocated similar views to Raup.
Raup is not challenging natural selection as a cause of modification of species; he just claimed that gradual change by natural selection is not the only mechanism of evolution as non-gradual extinction events also have a role.The Role of Extinction in Evolution by David M. Raup (1994) Proc. Natl. Acad. Sci. USA 91:6758-6763. Creationists however usually quote mine Raup to make out he is denying natural selection. Raup himself was no fan of creationists, and contributed to the anti-creationist book Scientists Confront Creationism.
===Mae-Wan Ho===
Mae-Wan Ho was a geneticist who has become well known for her criticism of the modern synthesis. Since the 1980s she wrote in publications that a paradigm shift has occurred in evolution due to discoveries in epigenetics which have disproven and replaced many of the tenets of neo-Darwinism.A New Paradigm for Evolution: Standard evolutionary theory sees little beyond the natural selection of random variation. Yet there's more to life by Mae-Wan Ho et al. (February 27, 1986) New Scientist. In 1984 she published with other scientists a book titled published Beyond Neo-Darwinism: An Introduction to the New Evolutionary Paradigm. The book received a mixed response from the scientific community but was strongly criticised by some scientists.
===Elisabet Sahtouris===
Elisabet Sahtouris, an evolutionary biologist, has opposed neo-Darwinism for its reductionistic gene centric view of organisms. According to Sahtouris organisms should be viewed as living systems and not just based on their genes. Her book Biology Revisioned (1998) advocates a form of "holistic biology" with consciousness and self-organizational factors having a role in the evolutionary process. Similar to Mae-Wan Ho her views have been criticised by some scientists. The general criticism of Sahtouris is that she is mixing science with new age themes.
===Shapiro and non-Darwinian mechanisms===
American biologist James A. Shapiro in his book Evolution: A View from the 21st Century (2011) has written that evolutionary mechanisms such as symbiogenesis, and are all non-Darwinian and can not be fitted into the modern evolutionary synthesis, as the modern synthesis is still working within a Darwinian framework. Shapiro believes many of these mechanisms fit better with a saltationist school rather than Darwin's strict advocacy of gradualism via "numerous, successive, slight variations". Shapiro also claims that natural selection's importance for evolution has been hugely overstated.Evolution: A View from the 21st Century by James A. Shapiro (2011) FT Press. ISBN 0132780933.
Jerry Coyne, a professor of biology and critic of non-Darwinian evolution, has denied these claims of Shapiro and has said all of the genetic mechanisms Shapiro discusses still fit into the Darwinian gradual framework of the modern synthesis and do not downgrade the efficacy of natural selection.Shapiro's anti-Darwinian book gets panned by Jerry Coyne (April 8, 2012 at 5:15 am) Why Evolution is True.
On the subject of Shapiro and the role of natural selection in evolution, evolutionary biologist Adam S. Wilkins has written: 
Wilkins also wrote that arguments from paleontology have shown the importance of natural selection in long-term trends of morphological change and that non-Darwinian evolutionary scientists who play down natural selection have not yet explained which mechanism is responsible for such trends apart from orthogenesis which is considered obsolete by most scientists. Creationists usually quote mine and misunderstand the work of Shapiro in an attempt to make out evolution is falling apart however as scientists have pointed out Shapiro is not questioning the fact of evolution, he is only questioning the role of natural selection in evolution which is perfectly valid science, "and will either stand the test of time, and questioning by other scientists, or it will fall".Doubt and dogmatism in science — questioning natural selection by Anne Buchanan (February 7, 2012) The Mermaid's Tale.
There has also been a controversy over natural genetic engineering (NGE), a process described by Shapiro to account for novelty created in the process of biological evolution. Shapiro developed NGE in peer-reviewed publications and later in his book Evolution: A View from the 21st Century. NGE has become controversial, as it rejects the neo-Darwinian synthesis and the It has been widely reviewed by the scientific community and criticised by some scientists.
===Eugene Koonin===
Molecular biologist Eugene Koonin has written in his publications that the neo-Darwinian concepts of biological evolution are considered outdated due to recent discoveries in comparative genomics and In his book The Logic of Chance: The Nature and Origin of Biological Evolution (2011) Koonin wrote:
Koonin has called for a paradigm shift in evolutionary biology which he believes has replaced many parts of the neo-Darwinian synthesis. He has written for example "In the post-genomic era, all the major tenets of the modern synthesis have been, if not outright overturned, replaced by a new and incomparably more complex vision of the key aspects of evolution".The Origin at 150: Is a new evolutionary synthesis in sight? by Eugene Koonin (2009) Trends in Genetics 25(11):473-475. doi:10.1016/j.tig.2009.09.007.Darwinian evolution in the light of genomics by Eugene Koonin (2009) Nucleic Acids Research 37(4):1011-1034. doi:10.1093/nar/gkp089. He also wrote a paper in 2009 titled Is evolution Darwinian or/and Lamarckian? in which he claimed certain evolutionary mechanisms fit the criteria as evidence for Lamarckian inheritance and came to the conclusion that both "Darwinian and Lamarckian modalities of evolution appear to be important, and reflect different aspects of the interaction between populations and the environment."Is evolution Darwinian or/and Lamarckian? by Eugene V. Koonin & Yuri I. Wolf (2009) Biology Direct 4:42. doi:10.1186/1745-6150-4-42.
===Extended Synthesis===
Over the past decade, new conceptions of evolutionary theory have emerged going under the umbrella term of the "Extended Synthesis," which is intended to modify the existing Modern Synthesis. This proposed extended synthesis incorporates new possibilities for integration and expansion in evolutionary theory, such as Evo-devo, and Its proponents include Massimo Pigliucci, and Eva Jablonka.An Extended Synthesis for Evolutionary Biology by Massimo Pigliucci (2009) Ann. N.Y. Acad. Sci. 1168: 218–228 (2009). doi:10.1111/j.1749-6632.2009.04578.x. Archived from October 14, 2017. In 2008 sixteen scientists met at the Konrad Lorenz Institute in Altenberg, Austria to propose an extended synthesis. Creationists and intelligent design advocates have misunderstood and distorted the events of this meeting (see Altenberg 16 controversy) by claiming the scientists involved with the extended synthesis are "anti-Darwinian". Massimo Pigliucci has explained that the extended synthesis is not "anti-Darwinian" (Pigliucci and Müller, 2010). Whilst the extended synthesis does advocate some "non-Darwinian" mechanisms such as epigenetic inheritance or niche construction it does not reject Darwinian natural selection and should not be confused with non-Darwinian evolution.
==Neutral evolution==
The neutral theory of molecular evolution claims that most allelic variation and substitutions in proteins and DNA are neutral. Neutral evolution has been called a non-Darwinian evolution, as most substitutions are caused via genetic drift rather than natural selection.Population Genetics: A Concise Guide by John H. Gillespie (2004) Johns Hopkins University Press. 0801880092. 2nd edition. A paper was written on the subject in 1969 called . Neutral theory was first developed by Motoo KimuraProfiles: Motoo Kimura History of Recent Science and Technology Project, California Institute of Technology Library. and his student Tomoko Ohta.Profiles: Tomoko Ohta, History of Recent Science and Technology Project, California Institute of Technology Library
==Non-Darwinian selection==
Non-Darwinian selection refers to changes in populations produced by selection processes other than natural selection.non-Darwinian selectionnicht-darwinsche Selektion (ger.) BioConcepts (archived from April 15, 2015). 
===Holistic selection===
Jan Smuts developed a non-Darwinian form of internal selection in his book Holism and Evolution (1926):
 
===Teleonomic selection===
Peter Corning has coined the term "teleonomic selection" to describe purposive behavior playing an important causal role in initiating evolutionary changes. He described this selection theory as "living beings that do the selecting... a "purposeful process" that is intimately related to meeting basic survival reproductive needs in a given context." Corning does not reject natural selection and has written that teleonomic selection works with it to affect evolutionary change.Nature's Magic: Synergy in Evolution and the Fate of Humankind by Peter Corning (2003) Cambridge University Press. ISBN 0521825474.
Corning later termed his theory of teleonomic selection as "neo-Lamarckian selection". According to Corning:
===Social selection===
Evolutionary biologist Joan Roughgarden has presented a theory termed "social selection" as an alternative to sexual selection. Roughgarden has criticised sexual selection in her publications as she believes it has been contradicted by various sexual behaviours in the animal kingdom and has written it fails to explain the homosexuality that has been documented in over 450 different vertebrate species.Evolution's Rainbow: Diversity, Gender and Sexuality in Nature and People by Joan Roughgarden (2004) University of California Press. ISB 0520240731. Many scientists have rejected the claims of Roughgarden.
==Spiritual evolution==
Most non-Darwinian evolutionary mechanisms that have been presented have been natural, however some scientists and writers have advocated theistic or spiritual evolutionary mechanisms. Alfred Russel Wallace and the biologist St. George Jackson Mivart were two early scientists to invoke supernatural factors in evolution. 
Regarding the evolutionary ideas of Wallace and Mivart, Thomas Henry Huxley wrote:
Similar ideas later appear in the writings of 
Oliver L. Reiser believed that evolution was driven by geomagnetic forces. He claimed that there was a "memory field" around the Earth, which he called the "psychosphere", which influenced evolution.
===Vitalism===
In the late 19th century, scientists who supported vitalism thought Darwin's theories were too materialistic to explain the complexity of life and proposed mechanisms of vital or psychic evolution. Wilhelm Wundt, August Pauly, Eduard von Hartmann, Hans Dreisch and Eric Wasmann abandoned natural selection for internal, vital principles of psychic evolution.Darwin and the Emergence of Evolutionary Theories of Mind and Behavior by Robert J. Richards (1989) University of Chicago Press. ISBN 0226712001.
The biologist Hans Driesch (1867-1941) held that both Darwinian and Lamarckian evolutionary mechanisms were unable to explain evolution adequately. This according to Dreisch was because natural selection was a negative principle, which could explain the elimination of particular forms, but not the creation of new diversities. Instead Driesch proposed that living organisms were driven by a vital principle, a nonmechanical "life force" which he proposed to represent by Aristotle's term "entelechy". 
By the 1930s, vitalism had fallen out of favour. On discussing the history of vitalism in biology, Ernst Mayr wrote in 1988: "Vitalism has become so disreputable a belief in the last fifty years that no biologist alive today would want to be classified as a vitalist. Still, the remnants of vitalist thinking can be found in the work of Alistair Hardy, Sewall Wright, and Charles Birch, who seem to believe in some sort of nonmaterial principle in organisms."Toward a New Philosophy of Biology: Observations of an Evolutionist by Ernst Mayr (1988) Belknap Press of Harvard University Press. ISBN 0674896653.
In recent years, some non-scientists and new age writers have defended forms of vitalism, such as arguments for the existence of an immaterial "life force" directing evolution. Such views, however, have been deemed pseudoscience by the scientific community.
==Non-Darwinian evolution and creationism==
Unfortunately, most religious creationists and intelligent design advocates usually equate evolution with "Darwinism" and it is clear many of these authors out of dishonesty do this on purpose. Where it is clear non-Darwinian scientists or writers are only debating the role of natural selection in evolution and the mechanisms which brought evolution about, creationists often quote mine and distort quotes from these scientists in an attempt to create the impression that these scientists were actually denying evolution.
In 2011, biologist A. L. Hughes published a paper titled Evolution of adaptive phenotypic traits without positive Darwinian selection, in which he proposed a non-Darwinian mechanism of adaptation which he termed "plasticity–relaxation–mutation" (PRM).Evolution of adaptive phenotypic traits without positive Darwinian selection by A. L. Hughes (2012) Heredity 108:347–353. doi:10.1038/hdy.2011.97. The paper has been misunderstood and quote mined by creationists to suggest that evolution is falling apart.Paper in Heredity explores non-Darwinian evolution (November 11, 2011) Uncommon Descent.A. L. Hughes’s New Non-Darwinian Mechanism of Adaption Was Discovered and Published in Detail by an ID Geneticist 25 Years Ago by Wolf-Ekkehard Lönnig (December 7, 2011, 1:39 PM) Evolution News & Science Today.
 
Intelligent design writer Jean Staune has written a paper on non-Darwinian evolution and has listed Michael Denton and Michael Behe as "non-Darwinian evolutionists", since they accept common descent. Staune claims the way forward for the ID movement is for IDers to accept common descent, but to propose non-Darwinian mechanisms to downplay or replace natural selection. However, it is clear from Staun's paper that he has no interest in proposing any natural mechanisms for evolution and is only interested in metaphysical speculation.Darwinism Design and Purpose: A European Perspective by Jean Staune. This paper was prepared for “Science and Religion: Global Perspectives” June 4-8, 2005, in Philedelphia, PA, USA, a program of the Metanexus Institute.
Creationists have also incorrectly described punctuated equilibrium (PE) as "non-Darwinian". Richard Dawkins declared that "[PE] lies firmly within the neo-Darwinian synthesis” in his book The Blind Watchmaker.
==See also==
*Stabilization Theory by Eugene M. McCarthy, a modern-day theory of non-Darwinian evolution
*Terence McKenna — psychedelic drugs caused hominid evolution
==External links==
*A non-Darwinian theory of evolution proposed 
*Bibliography of Natural Teleology and Non-Darwinian Evolution by James Barham
*Challenges to the Evolutionary Synthesis by Richard M. Burian
*Extensions & alternative evolutionary theories Towards The Third Evolutionary Synthesis, by Gert Korthof
*Outlines for a Post-Darwinian Biology by Kalevi Kull
*Lamarck Revisited
==Further reading==
*Peter Bowler Evolution: The History of an Idea (2009) ISBN 978-0520261280
*Thomas Glick The Comparative Reception of Darwinism (1988) ISBN 978-0226299778
*James Moore The Post-Darwinian Controversies: A Study of the Protestant Struggle to Come to Terms with Darwin in Great Britain and America, 1870-1900 (1981) ISBN 978-0521285179
*Nicolaas Rupke Richard Owen: Biology without Darwin (2009) ISBN 978-0226731773 
*Peter Vorzimmer Charles Darwin: The Years of Controversy: The Origin of Species and its critics, 1859-1882 (1970) ISBN 978-0877220015
==References==
Category:Evolution
Category:Biology