Dexamethasone (Decadron)

==General information==
Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, antiemetic properties, and anti-inflammatory effects.Dexamethasone (Decadron) package insert Dexamethasone (Decadron) package insert (locally hosted backup)
Route: PO, IV, IM
Extravasation: no information
*Steroid conversions
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias or the prescribing information. 
==Diseases for which it is established==
*Immune thrombocytopenia (FDA)
*Leukemias (FDA)
**B-cell acute lymphoblastic leukemia
**T-cell acute lymphoblastic leukemia
*Lymphomas (FDA)
**Anaplastic large cell lymphoma
**Burkitt lymphoma
**Classical Hodgkin lymphoma
**CNS lymphoma
**Diffuse large B-cell lymphoma
**Extranodal NK- and T-cell lymphoma, nasal type
**Indolent lymphoma
***Follicular lymphoma
***Waldenström macroglobulinemia
**HIV-associated lymphoma
**Mantle cell lymphoma
**NK- and T-cell lymphoma
**Peripheral T-cell lymphoma
**Primary mediastinal B-cell lymphoma
**Transformed lymphoma
*Light-chain (AL) amyloidosis (PMDA)
*Multiple myeloma (PMDA)
*Warm autoimmune hemolytic anemia (FDA)
==Diseases for which it is used==
*Hemophagocytic lymphohistiocytosis
*Plasma cell leukemia
*POEMS syndrome
*Smoldering multiple myeloma
==Diseases for which it was used==
*Acute myeloid leukemia
*Prostate cancer
==Patient drug information==
*Dexamethasone (Decadron) package insert
*Dexamethasone (Decadron) patient drug information (Chemocare)Dexamethasone (Decadron) patient drug information (Chemocare)
*Dexamethasone (Decadron) patient drug information (UpToDate)Dexamethasone (Decadron) patient drug information (UpToDate)
==History of changes in FDA indication==
*Uncertain date: Approved for certain hematologic disorders: acquired (autoimmune) hemolytic anemia, congenital (erythroid) hypoplastic anemia (Diamond-Blackfan anemia), idiopathic thrombocytopenic purpura in adults, pure red cell aplasia, and selected cases of secondary thrombocytopenia.
*Uncertain date: Approved for certain neoplastic diseases: For the palliative management of leukemias and lymphomas.
==History of changes in EMA indication==
*1952-01-01: EURD
==History of changes in PMDA indication==
*2010-06-18: New additional indication and a new dosage for the treatment of multiple myeloma.
*2021-08-25: New indication and a new dosage for the treatment of systemic AL amyloidosis.
==Also known as==
*Generic names: dexamethasone acetate, dexamethasone sodium, dexamethasone sodium metasulfobenzoate, dexamethasone sodium phosphate, dexamethasone sodium succinate, dexamethasone sodium sulfate
*Brand names:
Synonyms 	Synonyms 	Synonyms 	Synonyms 	Synonyms 	Synonyms 	Synonyms 	Synonyms
Aacidexam 	Acetato DE Dexametasona	Acetazona 	Acolon 	Adrecort 	Adrekon 	Aeroseb-DEX 	Afpred Forte-Dexa
AK-DEX 	Aldron 	Alfalyl 	Alpermell 	Amumetazon 	Anemul 	Aphtasolon 	Apidex
Arcodexan 	Auxiloson 	Auxison 	Auxisone 	B Dexzol 	Bexine 	Beyonas Dexa 	Bisuo DS
Brulin 	Bucokon 	Bufadexon 	Butiol 	Canalon 	Carbidu 	Carulon 	Cebedex
Cellacort 	Celudex 	Cetadexon 	Colircusi Dexametasona	Corodex 	Corson 	Corsona 	Corsone
Corsum 	Corticoidex 	Cortidax 	Cortidex 	Cortidexason 	Cortitop 	Coyensu 	D-Cort
Dacrosone 	Daidoron 	Dalalone 	Danason 	Danasone 	Daxilone 	Decacin 	Decaderm
Decadolone 	Decadran 	Decadron 	Decadronal 	Decadronfosfat	Deca Forte 	Decafos 	Decalin
Decalon 	Decalona 	Decan 	Decans 	Decaron 	Decason 	Decasone 	Decaspray
Decazol 	Decdak 	Decdan 	Decicort 	Decilone 	Decobel 	Decolite 	Decone
Decordex 	Decorex 	Decoron 	Decorten 	Dectan 	Dectancyl 	Deexa 	Deflaren
Dekesu 	Dekisachosei 	Dekort 	Deksa 	Deksalon 	Deksamet 	Dellamethasone	Deltafluorene
Demasone 	Demeson 	Dermadex 	Dermidron 	Deronil 	Deron S 	Derson 	Dersone
Desalark 	Desametasone Fosf 	Desason 	Deson 	Detametazon 	Detasone 	Dethamedin 	Dexa
Dexabene 	Dexabeta 	Dexacen-4 	Dexacilin 	Dexacip 	Dexa Clinit 	Dexacollyre 	Dexacom
Dexacort 	Dexacortal 	Dexacortin 	Dexacortisone 	Dexacortisyl 	Dexacotsil 	Dexacron 	Dexacutis
Dexaden 	Dexaderm 	Dexaderme 	Dexadermil 	Dexadon 	Dexadrol 	Dexadron 	Dexaedo
Dexafar 	Dexafarm 	Dexaflam 	Dexaflan 	Dexagalen 	Dexagee 	Dexagel 	Dexagenta
Dexaglos 	Dexagreen 	Dexagrin 	Dexahexal 	Dexaleniens 	Dexalocal 	Dexaltin 	Dexam
Dexamag 	Dexamark 	Dexame 	Dexamecortin 	Dexamedis 	Dexamedix 	Dexamedron 	Dexameral
Dexameson 	Dexamesone 	Dexamet 	Dexametason 	Dexametasona 	Dexametax 	Dexametazon 	Dexametazona
Dexameth 	Dexamethason 	Dexamethasonum	Dexamethazon 	Dexamethazone 	Dexametin 	Dexametisona 	Dexametonal
Dexametrat 	Dexamex 	Dexamil 	Dexamine 	Dexaminor 	Dexamo 	Dexamonozon N 	Dexanel
Dexan 	Dexanil 	Dexano 	Dexaphos 	Dexapolcort 	Dexapro 	Dexaril 	Dexaroid
Dexaron 	Dexart 	Dexasin 	Dexasine 	Dexasol 	Dexasolone 	Dexason 	Dexasone
Dexasonlin 	Dexatab 	Dexaton 	Dexatop 	Dexatotal 	Dexaval 	Dexaven 	Dexavet
Dexawal 	Dexawieb 	Dexazen 	Dexazona 	Dexazone 	Dexicorta 	Dexin 	Dexinga
Dexion 	Dexmene 	Dexmesone 	Dexmetha 	Dexmethasone 	Dexmethsone 	Dexona 	Dexone
Dexonium 	Dexoptic 	Dexpak 	Dexsol 	Dexstar 	Dextason 	Dexthasol 	Dexton
Dextrasone 	Dicorsone 	Dicosheun 	Diometa 	Dison 	DM Solone 	Donray 	Dorison
Doronil 	Drenex 	Drxaline 	Elixirmethasone 	Epidexone 	Epidrone 	Erladexone 	Ermethasone
ETA Cortilen 	Etason 	Euromethasone 	Fada Dexametasona 	Fadametasona 	Faridexon 	Fexadron 	Fortecortin
Fosfato Dissodico Dexametasona	Gammacorten 	Gemisona 	Glymesason 	Grathazon 	Hexadecadrol	Hexadrol 	HI-Methasone
Hopamethasone 	Idizone 	Indexon 	Inthesa-5 	Irzamethazone 	Isodexam 	Isopto 	Kaarmepakkaus
Kalmethasone 	Kanadex 	Kodolo 	Kosa 	Kovintong 	Lanadexon 	Licoson 	Limethason
Lipotalon 	Lisoderme 	Lodex 	Lodexa 	Lokalison-F 	Lormine 	Loverine 	Lupidexa
Luxazone 	Maradex 	Maxidex 	Mecoxon 	Medesone 	Medexasone 	Mediamethasone	Medicort
Medidex 	Megacort 	Megadex 	Mephameson 	Mephamesona 	Mephamesone 	Mephamesone-4 	Meradexon
Merideca 	Mesadoron 	Metalexina 	Metasolon 	Metax 	Metaxon 	Metcort 	Methaderm
Methasone 	Mexasone 	Mexaton 	Migradexan 	Millicorten 	Minidex 	Mitasone 	Molacort
Mycidex 	Neodex 	Nexadron 	Nodevex 	Nufadex M 	Ocedran 	Ocudex 	Oftadek
Oftadex 	Omedexon 	Onadron 	Ophth-DEX 	Ophthasona 	Opticort 	Orazone 	Ordex
Orgadrone 	Penatone 	Penodex 	Phenodex 	Pidexon 	Plavex 	Plidexa 	Prodexon
Pyderma 	Pyradexon 	Rally-A 	Randexa 	Redexon 	Rednisone 	Reusan 	Rocolone
Ronic 	Roximeth 	Rupedex 	Santeson 	Sawasone 	Scandexon 	Selftison 	Shirodex
Shuayan 	Smile 	Solcort 	Soldesam 	Soldesanil 	Soldex 	Soludecadron 	Solupen
Sonexa 	SP Cordexa 	Spersadex 	Spondy-Dexa 	Stedex 	Steralol 	Sterasone 	Steron
Superprednol 	Supertendin-Depot N 	Suprason 	Surodex 	Sydencort 	Syndexa 	Tavesona 	Teanlang
Teikason Nidek 	Tekuron 	Thilodex 	Thilodexine 	Totocortin 	Tuttozem N 	Ucalon 	Udicort
Unidex 	Unidexa 	Unisone 	Visualin 	Visumetazone 	Voalla 	Windex 	Wymesone
Xasone 	Xine 	Zalucs 	Zecaxon 	Zenos 	Zydexa 	Baycadron 	ZoDex
Neofordex 	LenaDex 	Hemady 	 	 	 	 	
==References==
Category:Drugs
Category:Intramuscular medications
Category:Intravenous medications
Category:Oral medications
Category:Steroids
Category:Anaplastic large cell lymphoma medications
Category:B-cell acute lymphoblastic leukemia medications
Category:Burkitt lymphoma medications
Category:Classical Hodgkin lymphoma medications
Category:CNS lymphoma medications
Category:Diffuse large B-cell lymphoma medications
Category:Extranodal NK- and T-cell lymphoma, nasal type medications
Category:Follicular lymphoma medications
Category:Hemophagocytic lymphohistiocytosis medications
Category:HIV-associated lymphoma medications
Category:Immune thrombocytopenia medications
Category:Indolent lymphoma medications
Category:Light-chain (AL) amyloidosis medications
Category:Mantle cell lymphoma medications
Category:Multiple myeloma medications
Category:NK- and T-cell lymphoma medications
Category:Peripheral T-cell lymphoma medications
Category:Plasma cell leukemia medications
Category:POEMS syndrome medications
Category:Primary mediastinal B-cell lymphoma medications
Category:Smoldering multiple myeloma medications
Category:T-cell acute lymphoblastic leukemia medications
Category:Transformed lymphoma medications
Category:Waldenström macroglobulinemia medications
Category:Acute myeloid leukemia medications (historic)
Category:Prostate cancer medications (historic)
Category:FDA approved in 1958
Category:EMA approved in 1952
Category:WHO Essential Cancer Medicine
Category:WHO Essential Pain and Palliative Care Medicine