Эй, не надо мне грубить, пожалуйста. По английски читаете? Если -да, то тогда прочтите здесь, топик за 10/6/07:http://infertilityblog.blogspot.com/2007_10_01_archive.htmlThe first is that the natural CL and the extra CLs that are produced during ovulation induction with insemination are different than the CL of IVF. The CLs of IVF were all disturbed by the IVF needle. The CLs from IVF all started as follicles containing eggs. At the retrieval, the needle is placed into the follicle, the egg is removed, and other cells can also be removed. The follicle is mostly fluid, but it also contains tons of cells that make up the follicle and surround the egg. These are called the granuslosa cells, and these are the cells that convert to progesterone CL cells after ovulation. So if the needle removes some of these cells, as is usually the case, the CL may not work as well and less progesterone would be produced.The second has to do with the IVF medications. The CL makes the hormone progesterone, but the CL needs a hormone to help it perform this function. Leutinizing Hormone(LH) is the one. Yes the famous LH, of the LH surge. LH comes from the pituitary gland, and it is produce in high amounts just before ovulation to get ovulation to occur. (for IVF we use the LH substitute hCG, just to help with the timing). After ovulation, LH comes from the pituitary gland, in smaller amounts, to “leutinize” the follicle, or to get it to make the progesterone. LH is secreted throughout the luteal phase to keep the CL making progesterone. If a pregnancy occurs, the hCG from the pregnancy takes over to stimulate the CL progesterone system. If there is a problem with LH production in the luteal phase, there will be a problem with progesterone production and there will be a problem with the pregnancy.Almost all women who undergo IVF are given a medication that causes a problem for LH production. Whether it’s Lupron or Antagon, LH production stops. Sounds bad? No it’s good, at least initially. Stopping LH means preventing a premature LH surge, which can ruin 10% of IVF cycles. In a natural pregnancy, or when doing iui, surges are fine, they cause ovulation. In IVF, we need to time the retrieval to the hour, so that a surge at the wrong time ruins everything. Therefore, we give medications to stop LH, but what they do is stop LH for a while, and this compromises the ability of the to make progesterone.