With excellent customer satisfaction rankings and minivans that are the leaders in fuel efficiency, Honda and Toyota are the clear winners in this vehicle category. Toyota may have a slightly higher reliability record than Honda, but Honda gets better "accident avoidance" ratings which means a potentially safer ride. Crash test ratings show that both the Honda Odyssey and Toyota Sienna minivans perform admirably. The Toyota Sienna minivan does offer all-wheel drive (AWD) which the Honda does not. It may come down to pricing and incentives that make one look better than the other when it comes time to buy. http://www.consumersearch.com/minivan-reviews