List of Fatigue episodes

The first and only season of the American medical thriller drama Fatigue was released on HBO Max in 2025. The series were mainly directed and written by Edgar Ivanov, a Kazakhstani-Canadian writer.
==Premise==
Set in the modern-day Detroit, Michigan, the series tells of the personnel of a fictitious St. Anne's Hospital. A condition labeled as "avian respiratory syndrome" starts plaguing East Asia, and sometime later appears in the United States, causing a fair amount of panic, misinformation, stupidity and unrest.
The series goes through the entire timeline of the pandemic, from its start with the outbreak in East Asia, to its end with mass vaccination campaigns, and is largely based on the COVID-19 pandemic, which affected the author negatively.
==Episodes==
No. overall 	No. in season 	Title 	Directed by 	Written by
1 	1 	Normalcy 	Edgar Ivanov 	Edgar Ivanov
With the news reporting about the very distant outbreak in East Asia, life is yet normal in the United States, and Detroit in particular. The St. Anne's medical personnel doesn't know much trouble yet.One of the nurses, Andrew (Lou Taylor Pucci) is thinking about how to approach his colleague and love interest, Astrid (Hannah Murray). In the meanwhile, two friends, James (Alfie Allen) and Odin (Iwan Rheon) are spending a lot of time together.This episode largely serves as an introductory one. 	With the news reporting about the very distant outbreak in East Asia, life is yet normal in the United States, and Detroit in particular. The St. Anne's medical personnel doesn't know much trouble yet.One of the nurses, Andrew (Lou Taylor Pucci) is thinking about how to approach his colleague and love interest, Astrid (Hannah Murray). In the meanwhile, two friends, James (Alfie Allen) and Odin (Iwan Rheon) are spending a lot of time together.This episode largely serves as an introductory one. 	With the news reporting about the very distant outbreak in East Asia, life is yet normal in the United States, and Detroit in particular. The St. Anne's medical personnel doesn't know much trouble yet.One of the nurses, Andrew (Lou Taylor Pucci) is thinking about how to approach his colleague and love interest, Astrid (Hannah Murray). In the meanwhile, two friends, James (Alfie Allen) and Odin (Iwan Rheon) are spending a lot of time together.This episode largely serves as an introductory one. 	With the news reporting about the very distant outbreak in East Asia, life is yet normal in the United States, and Detroit in particular. The St. Anne's medical personnel doesn't know much trouble yet.One of the nurses, Andrew (Lou Taylor Pucci) is thinking about how to approach his colleague and love interest, Astrid (Hannah Murray). In the meanwhile, two friends, James (Alfie Allen) and Odin (Iwan Rheon) are spending a lot of time together.This episode largely serves as an introductory one. 	With the news reporting about the very distant outbreak in East Asia, life is yet normal in the United States, and Detroit in particular. The St. Anne's medical personnel doesn't know much trouble yet.One of the nurses, Andrew (Lou Taylor Pucci) is thinking about how to approach his colleague and love interest, Astrid (Hannah Murray). In the meanwhile, two friends, James (Alfie Allen) and Odin (Iwan Rheon) are spending a lot of time together.This episode largely serves as an introductory one.
2 	2 	Arrival 	Edgar Ivanov 	Edgar Ivanov
The disease starts to spread quite quickly when Fall comes, hitting Japan, Southeast Asia and India. This becomes an object for concern from the World Health Organization.But soon, the Centers for Disease Control and Prevention start to panic as well, when multiple people are reported to be ill with a mysterious condition in Alaska, with cases multiplying in Anchorage. When the disease hits the 48 contiguous states, starting with Washington, first measures are implemented - thus, Detroit begins its first preparations, even though they start from just some businesses and not the government. 	The disease starts to spread quite quickly when Fall comes, hitting Japan, Southeast Asia and India. This becomes an object for concern from the World Health Organization.But soon, the Centers for Disease Control and Prevention start to panic as well, when multiple people are reported to be ill with a mysterious condition in Alaska, with cases multiplying in Anchorage. When the disease hits the 48 contiguous states, starting with Washington, first measures are implemented - thus, Detroit begins its first preparations, even though they start from just some businesses and not the government. 	The disease starts to spread quite quickly when Fall comes, hitting Japan, Southeast Asia and India. This becomes an object for concern from the World Health Organization.But soon, the Centers for Disease Control and Prevention start to panic as well, when multiple people are reported to be ill with a mysterious condition in Alaska, with cases multiplying in Anchorage. When the disease hits the 48 contiguous states, starting with Washington, first measures are implemented - thus, Detroit begins its first preparations, even though they start from just some businesses and not the government. 	The disease starts to spread quite quickly when Fall comes, hitting Japan, Southeast Asia and India. This becomes an object for concern from the World Health Organization.But soon, the Centers for Disease Control and Prevention start to panic as well, when multiple people are reported to be ill with a mysterious condition in Alaska, with cases multiplying in Anchorage. When the disease hits the 48 contiguous states, starting with Washington, first measures are implemented - thus, Detroit begins its first preparations, even though they start from just some businesses and not the government. 	The disease starts to spread quite quickly when Fall comes, hitting Japan, Southeast Asia and India. This becomes an object for concern from the World Health Organization.But soon, the Centers for Disease Control and Prevention start to panic as well, when multiple people are reported to be ill with a mysterious condition in Alaska, with cases multiplying in Anchorage. When the disease hits the 48 contiguous states, starting with Washington, first measures are implemented - thus, Detroit begins its first preparations, even though they start from just some businesses and not the government.
3 	3 	Condition 	Edgar Ivanov 	Edgar Ivanov
With October being on the doorstep, the disease finally appears in Detroit. The first ever case gets hospitalized into one of the city's central hospitals, but it causes a fair amount of panic, as well as some minor panic buying. The nurses of the St. Anne's Hospital are slowly being instructed on how to deal with possibly infected patients, but they are still underprepared when the first ever case appears in the hospital. 	With October being on the doorstep, the disease finally appears in Detroit. The first ever case gets hospitalized into one of the city's central hospitals, but it causes a fair amount of panic, as well as some minor panic buying. The nurses of the St. Anne's Hospital are slowly being instructed on how to deal with possibly infected patients, but they are still underprepared when the first ever case appears in the hospital. 	With October being on the doorstep, the disease finally appears in Detroit. The first ever case gets hospitalized into one of the city's central hospitals, but it causes a fair amount of panic, as well as some minor panic buying. The nurses of the St. Anne's Hospital are slowly being instructed on how to deal with possibly infected patients, but they are still underprepared when the first ever case appears in the hospital. 	With October being on the doorstep, the disease finally appears in Detroit. The first ever case gets hospitalized into one of the city's central hospitals, but it causes a fair amount of panic, as well as some minor panic buying. The nurses of the St. Anne's Hospital are slowly being instructed on how to deal with possibly infected patients, but they are still underprepared when the first ever case appears in the hospital. 	With October being on the doorstep, the disease finally appears in Detroit. The first ever case gets hospitalized into one of the city's central hospitals, but it causes a fair amount of panic, as well as some minor panic buying. The nurses of the St. Anne's Hospital are slowly being instructed on how to deal with possibly infected patients, but they are still underprepared when the first ever case appears in the hospital.
4 	4 	Spread 	Edgar Ivanov 	Edgar Ivanov
With more and more days passing in October, the disease slowly tries to take more and more lives in Detroit, with at least multiple dozen people being quarantined at the St. Anne's Hospital. One of the nurses starts to show symptoms of a respiratory infection, presumably getting infected from an intubated patient. She is hospitalized in the same hospital.Seeing the fast spread of the disease in South and Southeast Asia, East Africa, Europe and the United States, the World Health Organization officially declares the outbreak of ARS a pandemic. This causes a fair amount of panic buying, with people raiding and looting the stores. An incident with police brutality leads to some unrest in multiple cities. 	With more and more days passing in October, the disease slowly tries to take more and more lives in Detroit, with at least multiple dozen people being quarantined at the St. Anne's Hospital. One of the nurses starts to show symptoms of a respiratory infection, presumably getting infected from an intubated patient. She is hospitalized in the same hospital.Seeing the fast spread of the disease in South and Southeast Asia, East Africa, Europe and the United States, the World Health Organization officially declares the outbreak of ARS a pandemic. This causes a fair amount of panic buying, with people raiding and looting the stores. An incident with police brutality leads to some unrest in multiple cities. 	With more and more days passing in October, the disease slowly tries to take more and more lives in Detroit, with at least multiple dozen people being quarantined at the St. Anne's Hospital. One of the nurses starts to show symptoms of a respiratory infection, presumably getting infected from an intubated patient. She is hospitalized in the same hospital.Seeing the fast spread of the disease in South and Southeast Asia, East Africa, Europe and the United States, the World Health Organization officially declares the outbreak of ARS a pandemic. This causes a fair amount of panic buying, with people raiding and looting the stores. An incident with police brutality leads to some unrest in multiple cities. 	With more and more days passing in October, the disease slowly tries to take more and more lives in Detroit, with at least multiple dozen people being quarantined at the St. Anne's Hospital. One of the nurses starts to show symptoms of a respiratory infection, presumably getting infected from an intubated patient. She is hospitalized in the same hospital.Seeing the fast spread of the disease in South and Southeast Asia, East Africa, Europe and the United States, the World Health Organization officially declares the outbreak of ARS a pandemic. This causes a fair amount of panic buying, with people raiding and looting the stores. An incident with police brutality leads to some unrest in multiple cities. 	With more and more days passing in October, the disease slowly tries to take more and more lives in Detroit, with at least multiple dozen people being quarantined at the St. Anne's Hospital. One of the nurses starts to show symptoms of a respiratory infection, presumably getting infected from an intubated patient. She is hospitalized in the same hospital.Seeing the fast spread of the disease in South and Southeast Asia, East Africa, Europe and the United States, the World Health Organization officially declares the outbreak of ARS a pandemic. This causes a fair amount of panic buying, with people raiding and looting the stores. An incident with police brutality leads to some unrest in multiple cities.
5 	5 	Disturbance 	Edgar Ivanov 	Edgar Ivanov
Going into November, the disease starts ransacking cities. An unusually high mortality rate causes excessive panic, and serves as a reason for civil unrest to start in some places. Riots soon hit Detroit. Hundreds of patients arrive into the city's hospitals, some requiring hospitalization in the nearby cities. With hospitals filled to the brim, the nurses and doctors have to make sure patients stay stable. They have to work long shifts lasting multiple days. Multiple nurses are on the brink of a breakdown after seeing multiple deaths and not sleeping for a long time. A shortage of personal protective equipment (PPE) causes nurses to protest, sparking yet other instances of civil unrest. 	Going into November, the disease starts ransacking cities. An unusually high mortality rate causes excessive panic, and serves as a reason for civil unrest to start in some places. Riots soon hit Detroit. Hundreds of patients arrive into the city's hospitals, some requiring hospitalization in the nearby cities. With hospitals filled to the brim, the nurses and doctors have to make sure patients stay stable. They have to work long shifts lasting multiple days. Multiple nurses are on the brink of a breakdown after seeing multiple deaths and not sleeping for a long time. A shortage of personal protective equipment (PPE) causes nurses to protest, sparking yet other instances of civil unrest. 	Going into November, the disease starts ransacking cities. An unusually high mortality rate causes excessive panic, and serves as a reason for civil unrest to start in some places. Riots soon hit Detroit. Hundreds of patients arrive into the city's hospitals, some requiring hospitalization in the nearby cities. With hospitals filled to the brim, the nurses and doctors have to make sure patients stay stable. They have to work long shifts lasting multiple days. Multiple nurses are on the brink of a breakdown after seeing multiple deaths and not sleeping for a long time. A shortage of personal protective equipment (PPE) causes nurses to protest, sparking yet other instances of civil unrest. 	Going into November, the disease starts ransacking cities. An unusually high mortality rate causes excessive panic, and serves as a reason for civil unrest to start in some places. Riots soon hit Detroit. Hundreds of patients arrive into the city's hospitals, some requiring hospitalization in the nearby cities. With hospitals filled to the brim, the nurses and doctors have to make sure patients stay stable. They have to work long shifts lasting multiple days. Multiple nurses are on the brink of a breakdown after seeing multiple deaths and not sleeping for a long time. A shortage of personal protective equipment (PPE) causes nurses to protest, sparking yet other instances of civil unrest. 	Going into November, the disease starts ransacking cities. An unusually high mortality rate causes excessive panic, and serves as a reason for civil unrest to start in some places. Riots soon hit Detroit. Hundreds of patients arrive into the city's hospitals, some requiring hospitalization in the nearby cities. With hospitals filled to the brim, the nurses and doctors have to make sure patients stay stable. They have to work long shifts lasting multiple days. Multiple nurses are on the brink of a breakdown after seeing multiple deaths and not sleeping for a long time. A shortage of personal protective equipment (PPE) causes nurses to protest, sparking yet other instances of civil unrest.
6 	6 	Nightmare 	Edgar Ivanov 	Edgar Ivanov
Stepping into December, a crisis is going among medical workers. At least a couple of nurses from St. Anne's hospitals die of the infection, and one nurse commits suicide after finding symptoms, as she "didn't want to infect her colleagues".
The violent deaths of the patients and the colleagues, constant lack of sleep and food eventually causes multiple workers to break down in halls. Nurses try to get some sleep in the halls. They try to cheer each other up.One of the nurses finally understands that his girlfriend cheats on him while he's working in the hospital, but one day she is driven into the hospital by an ambulance. 	Stepping into December, a crisis is going among medical workers. At least a couple of nurses from St. Anne's hospitals die of the infection, and one nurse commits suicide after finding symptoms, as she "didn't want to infect her colleagues".
The violent deaths of the patients and the colleagues, constant lack of sleep and food eventually causes multiple workers to break down in halls. Nurses try to get some sleep in the halls. They try to cheer each other up.One of the nurses finally understands that his girlfriend cheats on him while he's working in the hospital, but one day she is driven into the hospital by an ambulance. 	Stepping into December, a crisis is going among medical workers. At least a couple of nurses from St. Anne's hospitals die of the infection, and one nurse commits suicide after finding symptoms, as she "didn't want to infect her colleagues".
The violent deaths of the patients and the colleagues, constant lack of sleep and food eventually causes multiple workers to break down in halls. Nurses try to get some sleep in the halls. They try to cheer each other up.One of the nurses finally understands that his girlfriend cheats on him while he's working in the hospital, but one day she is driven into the hospital by an ambulance. 	Stepping into December, a crisis is going among medical workers. At least a couple of nurses from St. Anne's hospitals die of the infection, and one nurse commits suicide after finding symptoms, as she "didn't want to infect her colleagues".
The violent deaths of the patients and the colleagues, constant lack of sleep and food eventually causes multiple workers to break down in halls. Nurses try to get some sleep in the halls. They try to cheer each other up.One of the nurses finally understands that his girlfriend cheats on him while he's working in the hospital, but one day she is driven into the hospital by an ambulance. 	Stepping into December, a crisis is going among medical workers. At least a couple of nurses from St. Anne's hospitals die of the infection, and one nurse commits suicide after finding symptoms, as she "didn't want to infect her colleagues".
The violent deaths of the patients and the colleagues, constant lack of sleep and food eventually causes multiple workers to break down in halls. Nurses try to get some sleep in the halls. They try to cheer each other up.One of the nurses finally understands that his girlfriend cheats on him while he's working in the hospital, but one day she is driven into the hospital by an ambulance.
7 	7 	Hopes 	Edgar Ivanov 	Edgar Ivanov
Some nurses are forced to spend Christmas and the New Year in the hospitals, and some could go home with their families. Connected by video calls, nurses and doctors cheer each other up, telling stories.Well into the January, it seems to people that the peak of the pandemic was already surpassed, with the amount of daily infections falling. This gives hope to some. 	Some nurses are forced to spend Christmas and the New Year in the hospitals, and some could go home with their families. Connected by video calls, nurses and doctors cheer each other up, telling stories.Well into the January, it seems to people that the peak of the pandemic was already surpassed, with the amount of daily infections falling. This gives hope to some. 	Some nurses are forced to spend Christmas and the New Year in the hospitals, and some could go home with their families. Connected by video calls, nurses and doctors cheer each other up, telling stories.Well into the January, it seems to people that the peak of the pandemic was already surpassed, with the amount of daily infections falling. This gives hope to some. 	Some nurses are forced to spend Christmas and the New Year in the hospitals, and some could go home with their families. Connected by video calls, nurses and doctors cheer each other up, telling stories.Well into the January, it seems to people that the peak of the pandemic was already surpassed, with the amount of daily infections falling. This gives hope to some. 	Some nurses are forced to spend Christmas and the New Year in the hospitals, and some could go home with their families. Connected by video calls, nurses and doctors cheer each other up, telling stories.Well into the January, it seems to people that the peak of the pandemic was already surpassed, with the amount of daily infections falling. This gives hope to some.
8 	8 	Relief 	Edgar Ivanov 	Edgar Ivanov
In March, news appear of a vaccine declared successful by Icelandic and Canadian science teams; the fact of it being approved by the WHO causes a lot of applause from nurses, and gives large hopes.Mass production takes up the entire Spring. Multiple doctors see the weather become warmer, the nature become greener, and the life become normal after a year of suffering. Many businesses are slowly opened. Some political dogfights do happen because of vaccines and vaccination campaigns, but people are steadily getting inoculated.With their movements free, and masks not necessary now, nurses visit their fallen colleagues and pay tributes. Multiple people finally meet with relatives. The series ends with the WHO declaring the pandemic is over in June.	In March, news appear of a vaccine declared successful by Icelandic and Canadian science teams; the fact of it being approved by the WHO causes a lot of applause from nurses, and gives large hopes.Mass production takes up the entire Spring. Multiple doctors see the weather become warmer, the nature become greener, and the life become normal after a year of suffering. Many businesses are slowly opened. Some political dogfights do happen because of vaccines and vaccination campaigns, but people are steadily getting inoculated.With their movements free, and masks not necessary now, nurses visit their fallen colleagues and pay tributes. Multiple people finally meet with relatives. The series ends with the WHO declaring the pandemic is over in June.	In March, news appear of a vaccine declared successful by Icelandic and Canadian science teams; the fact of it being approved by the WHO causes a lot of applause from nurses, and gives large hopes.Mass production takes up the entire Spring. Multiple doctors see the weather become warmer, the nature become greener, and the life become normal after a year of suffering. Many businesses are slowly opened. Some political dogfights do happen because of vaccines and vaccination campaigns, but people are steadily getting inoculated.With their movements free, and masks not necessary now, nurses visit their fallen colleagues and pay tributes. Multiple people finally meet with relatives. The series ends with the WHO declaring the pandemic is over in June.	In March, news appear of a vaccine declared successful by Icelandic and Canadian science teams; the fact of it being approved by the WHO causes a lot of applause from nurses, and gives large hopes.Mass production takes up the entire Spring. Multiple doctors see the weather become warmer, the nature become greener, and the life become normal after a year of suffering. Many businesses are slowly opened. Some political dogfights do happen because of vaccines and vaccination campaigns, but people are steadily getting inoculated.With their movements free, and masks not necessary now, nurses visit their fallen colleagues and pay tributes. Multiple people finally meet with relatives. The series ends with the WHO declaring the pandemic is over in June.	In March, news appear of a vaccine declared successful by Icelandic and Canadian science teams; the fact of it being approved by the WHO causes a lot of applause from nurses, and gives large hopes.Mass production takes up the entire Spring. Multiple doctors see the weather become warmer, the nature become greener, and the life become normal after a year of suffering. Many businesses are slowly opened. Some political dogfights do happen because of vaccines and vaccination campaigns, but people are steadily getting inoculated.With their movements free, and masks not necessary now, nurses visit their fallen colleagues and pay tributes. Multiple people finally meet with relatives. The series ends with the WHO declaring the pandemic is over in June.