The Aegean Crisis

If you're looking for the Marche Uprising, you've come to the right place.
The accounts of famed Milanese writer Giovanni Morosini describe the events that took place in the summer and autumn of 1529 during Episode XIV of Varna, including a brief conflict known as the Aegean Crisis.
"On May 6th, 1529, the Italic troops stormed Urbino, bringing an end to the First Italian War." - Giovanni Morosini.
Italia's victory had cost them their stability, so when the Aegean Revolt broke out in Italia's Greek territories in late May 1529, the revolt gained a lot of ground. This was also thanks to the Anatolian supplies which the rebels had received. Italia spent the next two months trying and failing to put down the rebellion, so in late July they threatened the Anatolians with war. Anatolia believed this to be an empty threat, but Italia followed through, thus beginning the Aegean Crisis. The remainder of the conflict is depicted in Morosini's writings:
"July 24th, 1529 was perhaps one of the most shocking days of modern times. The confrontation between the titans was inevitable, but not a single soul expected it to be this soon or sudden. The war started with Anatolia retaking several islands, as well as attacking Italic troops stationed in the Cypriot Condominium. The latter counterattacked in Crete, but was unable to muster enough troops in the region to fight in the islands. It soon all came to a stalemate. Reportedly, Italia planned to reinforce Greece with the armies stationed in Romagna. However, they couldn't. Those troops were needed elsewhere."
It was at this point, in early October, when the Marche Uprising broke out in Urbino and Umbria, distracting the Italic army in Romagna for a brief period. Morosini continues:
"The revolt at Urbino and neighbouring cities shocked the Italic elite. While it was put down rather quickly, the damage was already done. Anatolia counterattacked in Albania. At that point, King Ferrante had no choice but to accept an armistice. His local fighting capabilities were obliterated, and the country couldn't risk losing more land. The loss of several outposts to Anatolia is seen as the first defeat of Italia, albeit a minor one. But the rebellion in Umbria was more important. During the revolt, the rebels entered the old duke's palace. There, they found a letter, addressed to a certain someone."
It was not until December that Morosini discovered more news about the letter in question, during a brief period of crisis in his own homeland:
"Meanwhile, here in Milan... The city was in turmoil. The first Captain & Defender was dead. The elections were very disputed... but the winner was a merchant called Giano Loredan. And the letter was addressed to none other than him. And its contents, whatever they were... would bring a new age of fire over Italy."
New Year's Day 1530 saw no celebrations in Milan, for it was the day that Italia declared war on them, afterGiano Loredan had confronted King Ferrante about the letter. This "new age of fire" would soon be known as the Second Italian War.