Unnamed Federation starships (22nd century)

The following is a list of unnamed Federation starships in service during the 22nd century.
:See also unnamed Earth starships.
== By mission ==
=== Delos scout mission ===
An unnamed scout conducted first contact with the two civilizations of the Delos system in 2164. ()
=== Starfleet medical courier ===
This medical courier was scheduled for a rendezvous with the . The crew of the Franklin had been informed by Starfleet that this mission was 'imperative'. However, when the Franklin arrived at the last known coordinates of the courier, they discovered the courier was missing. An extensive, and eventually fruitless, search for the missing ship was launched. This ship was mentioned in the captain's logs of Captain Balthazar Edison. ()
Federation starships, 22nd