Martha Wayne

Martha Wayne (maiden name: Martha Kane) (b. 1946) (d. June 26th, 1981) was the sister of Jacob Kane, the sister-in-law of Gabrielle Kane, the aunt of Elizabeth and Kate Kane, the wife of Thomas Wayne, the daughter-in-law of Patrick Wayne, the mother of Bruce Wayne, the mother-in-law of Tony Stark, and the grandmother of her son's children. She and her husband were killed in front of their son in Crime Alley, which is what led to him deciding to become a vigilante, and put him in the care of their employee, Alfred Pennyworth. Not much else is known about her.
She, like her husband and niece Kate, makes a brief appearance in the little man who wasn't there.