The Destruction of the USS Intrepid

The USS Intrepid NCC-1631, a Federation starship crewed by Vulcans, was investigating the loss of contact with star system Gamma 7A in Sector 39J. It traversed that sector of space and encountered an unknown dark zone which was, unbeknownst at the time, slowly killing the ship's crew. The Intrepid soon encountered a giant space amoeba. The amoeba destroyed the USS Intrepid, killing all 400 Vulcans aboard. On the USS Enterprise, Commander Spock, the ship's first officer and science officer, telepathically sensed the deaths of the Vulcan crew of the USS Intrepid. He told his commander, Captain James T. Kirk "Captain, the Intrepid. She just...died. And the four hundred Vulcans aboard, all dead!"