Future Piccolo Character Facts

Future Piccolo is the alternate timeline counterpart of Piccolo in Future Trunks' timeline.
Future Piccolo's life was exactly the same as his main timeline counterpart's life until August of Age 764, when Future Goku used the Instant Transmission to arrive on Earth and kill Future Frieza and Future King Cold (something Future Trunks' arrival in the main timeline altered). Two years later, in Age 766, Goku died from a lethal Heart Virus and was unable to be wished back, due to the death being of natural cause. 
On the 12th of May, Age 767, two killer androids would appear. Coming to the defense of Earth's inhabitants, Piccolo and the other Z Fighters would engage the androids in battle. Future Piccolo was killed by Future Android 18 when she delivered a swift kick to his chest. He was the first of the Z Fighters to be killed by the androids (and, being fused with him, Future Nail died as well). 
When Future Piccolo died, Kami died as well, and so the Dragon Balls became useless; therefore, neither the Z Fighters, who would all also perish, nor any normal citizen who got killed by the Androids could be wished back.