Mrs. Fowler

Mrs. Fowler is the mother of Amy Farrah Fowler.
She appears briefly in "The Desperation Emanation" via webcam, where she speaks to Amy and meets Sheldon. Amy introduces him as her boyfriend and lies to her that they are having sex regularly. Mrs. Fowler is horrified by how bluntly they describe the frequency of their sex.
As a parent, she made a deal with her daughter to get her to do things. For example, in "The Robotic Manipulation", Amy says she agreed to date someone at least once a year in return for the use of her mother's George Foreman grill. Other words of wisdom from Mrs. Fowler include that playing hooky leads to addictions to reefers and jazz ("The Contractual Obligation Implementation") and that doing a puzzle is like having a thousand friends ("The Scavenger Vortex"). She wouldn't let Amy watch the movie "Grease" while growing up because she thought it would encourage her to join a gang ("The Rothman Disintegration").
In "The Bachelor Party Corrosion", Bernadette and Penny get Amy to call her mother to tell her that she broke up with Sheldon. When Amy beats around the bush, Penny grabs the phone and tells her that she just had her ears pierced, baked cookies in the shapes of penises, and broke up with Sheldon. Her mother sends Amy to Penny's closet, the same punishment that she put Amy through as a little girl. 
She is played by Annie O'Donnell and listed as "Mrs. Fowler" in the episode's closing credits.
She is the mother-in-law of Sheldon.
She physically appeared again in Season 11 finale "The Bow Tie Asymmetry" for her daughter's wedding. Penny picks the Fowlers up and Mrs. Fowler won't let her husband answer any questions and thinks her daughter is waiting for her to die to get her china. While visiting in Apartment 4A she adds that she wouldn't let Amy be in any school plays because actors only do drugs and have intercourse. Also she tells Amy that she shouldn't perform in videos (Fun with Flags) on the internet because she "knows what men do with them." Once the wedding is delayed, due to Sheldon and Amy off doing science, she wants to take Amy because she thinks Sheldon's gonna stand Amy up. Penny tells her to sit down because Sheldon would never hurt her. Angered at being treated like a child, she demands that Larry defend her, but Larry instead just thanks Penny for finally putting his wife in her place.
In "The Conjugal Configuration", Larry is hiding out in Sheldon and Amy's apartment. Mrs. Fowler comes over demanding that her husband return. He decided to take a break from their marriage. His wife comes over to talk things over with Penny and decides that she is a good person and they should become friends. Penny marches over to 4B and demands that Larry go home.
In "The Consummation Deviation", Sheldon first tries to bond with Larry Fowler who is more interested in Howard's magic tricks. He then stops in on his mother-in-law. At first they find nothing in common until they both bond over being mad at Amy. She had claimed that she and Sheldon couldn't visit because of Sheldon. He found her delightful which probably thrilled Amy. The episode ends with Larry accidentally cutting himself.
== Quotes ==
* "Larry, these are the people I'm gonna have to live with after you're dead!" (referring to Amy and Sheldon)
==Trivia==
* Annie O'Donnell also did the offstage voice of the mother of Dr. Oliver Lorvis in "The Misinterpretation Agitation". She also has worked with another guest star on The Big Bang Theory, Brent Spiner. In 1985–1987, she portrayed the wife of farmer Bob Wheeler in several episodes of Night Court before Brent Spiner is now Data on Star Trek: The Next Generation.
* Amy and her mother have an estranged relationship; they don't really get along very well, so they're not very close.
* Amy also has an aunt in Modesto, California and one on Bakersfield, California and a Flora.
* She is similar to Beverly Hofstadter in the series.
*Kathy Bates originally portrayed Charlie Harper's ghost on Two and a Half Men. 
==Gallery==
TBTA-6.jpg|Mama's little girl.
TBTA-27 Penny stares down Amy's mother.jpg|Sheldon loves Amy and would never hurt her.
TBTA-37.jpg|The Fowlers.
BowSym.jpg| Sheldon Cooper and Amy Farrah Fowler at their wedding with her parents.
31907945 1900576206667421 7111037409067794432 n.jpg|Fowler family.
Mrstr.png|Mrs F.
aws30.png|Mr. Fowler, are you okay back there?
aws31.png|Too busy for her mother?
aws32.png|Um.
aws33.png|She used to be such a devoted daughter.
aws52.png|There's Mama's girl!
aws53.png|Can you believe our little lamb is finally getting married?
aws54.png|Hi Dad. How you doing?
aws55.png|Hang me!
AWS65 Family meet before wedding.png|And did you know my Amy was Amelia Earhart in the eighth grade.
aws68.png|Those kids just take drugs and have intercourse.
Sheldon and Amy's wedding 96.png|Raj has a question.
Sheldon and Amy married 4.png|Raj's question.
aws112.png|This is taking too long.
Sheldon and Amy's wedding 3.png|Excuse me. Where are you going?
aws115.png|This whole thing was a big mistake.
aws116.png|Sit down.
aws117.png|Sheldon loves Amy.
Aws118 - Mary makes a comment.png|Mary applauding Penny.
aws123.png|So park it.
Aws151 Mark Hamill weds Amy and Sheldon.png|...and Amy Farrah Fowler...
aws153.png|The Fowlers.
aws174.png|The Fowlers.
aws193.png|The Fowlers.
Sheldon and Amy married 3.png|Penny and Leonard watching the Coopers. 
Sheldon and Amy married 2.png|Penny and Leonard following down the aisle. 
The Consummation Deviation 3.jpg|Mrs. Fowler.
The Consummation Deviation 6.jpg|Selfie.
The Consummation Deviation 31.png|Mrs. Fowler.
The Consummation Deviation 35.png|Showing her his foot fungus.
The Consummation Deviation 36.png|Selfie.
The Consummation Deviation 42.png|Finding some common ground.
The Consummation Deviation 46.png|Dinner with her folks.
The Consummation Deviation 48.png|Makes a knife disappear.
Hm13.png|“Blondie” is going to chew you up and spit you out.
Hm14.png|Hiding in bathroom.
Hm17.png|Not talking.
Hm21.png|We can be good friends.
The Consummation Deviation 3.jpg|Mrs. Fowler.
The Consummation Deviation 6.jpg|Selfie.
The Consummation Deviation 31.png|Mrs. Fowler.
The Consummation Deviation 35.png|Showing her his foot fungus.
The Consummation Deviation 36.png|Selfie.
The Consummation Deviation 42.png|Finding some common ground.
The Consummation Deviation 46.png|Dinner with her folks.
The Consummation Deviation 48.png|Makes a knife disappear.
Category:Amy's Family
Category:Characters
Category:Female Characters
Category:Mothers
Category:The Big Bang Theory Characters
Category:Amy Farrah Fowler
Category:Season 4 (The Big Bang Theory)
Category:Season 9 (The Big Bang Theory)
Category:Season 4 Characters (The Big Bang Theory)
Category:Season 11 (The Big Bang Theory)
Category:Season 12 (The Big Bang Theory)
Category:Married
Category:Season 9 Characters (The Big Bang Theory)
Category:Season 11 Characters (The Big Bang Theory)
Category:Season 12 Characters (The Big Bang Theory)
Category:The Big Bang Theory
Category:Cooper Family
Category:Grandmothers