Bio-Fusion (2023 Initiative P-8 animation)

Bio-Fusion is the process of reprogramming DNA to fuse organic body parts with biomechatronic and/or mechanical parts. It is a central plot element in the 2023 animated documentary Initiative P-8, where Otto Research, Sinmonger Logistics, and Mattel Logistics used it to convert people into "Cyberfolk" after it was outlawed for converting people into vehicles.
== History ==
In North America, Bio-Fusion was originally technology inherited from Professor Hans Götze of Germany and was used as an attempt to revive Derek Götze back from the dead following a tragic car accident. As Sodor Research began selling Bio-Fusion to other countries in multi-million pound deals, the frequency of Bio-Fusion experiments peaked in America. However, the majority of these experiments were conducted on animals to eliminate concerns by human rights activists. Following the Bio-Fusion ban in Britain in 1984, Bio-Fusion became banned publicly in Canada in 1987. However, despite the ban, Bio-Fusion is still technically continued in Canada, but only with companies that signed up to cooperate with the Canadian government. The Bio-Fusion trend eventually took off in the United States in the early 90s, where people were especially turned into passenger locomotives for Amtrak, but overall bio-fusing human subjects was done to a lesser extent in America than in Great Britain. The trend continued until 2015 when the documentary on Shed-17 was released. Following this, Bio-Fusion was instead adapted to turn willing Americans into cyborgs and more less trains and other vehicles. 
Like in Britain, Bio-Fusion experiments in America and Canada didn't have as much work put into them, but there were other experiments that had careful work put in them. The most notable example of the successful experiments was Jacob, a bio-fused locomotive working as Disneyland Railroad No. 6 "Joseph Robinette Biden Jr." and Alfred, who was Bio-Fused into a generic freelanced bullet train in 1997. Other than that, most of the bio-fused vehicles had various problems, with most of them either becoming too sick to work or dying during their operation or on their first test run as a result. 
Also, since the cyberfolk are technically people Bio-Fused into robotic animatronics, rather than just those with regular mechanical implants, they were just as flawed. In fact of the cyborgs had merely identical problems, with most of them either becoming too sick to work or dying during their operation or due to the animatronic mechanisms failing. 
=== How does Bio-Fusion work? ===
Splicing DNA with mechanical attachments is a way of manipulating the process of removing and joining segments of RNA, which are transcribed from DNA, to produce functional messenger RNA (mRNA) that can be translated into proteins. This process is normally performed by a complex molecular machine called the spliceosome, which consists of proteins and RNA molecules. However, some researchers have explored the possibility of using mechanical devices, such as magnetic tweezers or DNA origami, to apply forces or induce conformational changes to the RNA molecules, and thereby alter the splicing efficiency and outcome. This could have potential applications in biotechnology and medicine, such as modulating gene expression or creating hybrid organisms. However, there are also many challenges and limitations to this approach, such as the specificity, stability, and delivery of the devices, as well as the ethical and safety implications of modifying gene expression. Therefore, more research is needed to understand the mechanisms and consequences of DNA splicing with mechanical attachments. 
*Not all of this info explained is 100% accurate and has never been done before.* This is in a hypothetical event explained by GPT-4.
Category:Cyborg Technology
Category:2023 Initiative P-8 animation
Category:Science Fiction