Bulma Briefs/History

When Orion first arrived to Earth, Bulma was increasingly jealous that Vegeta was paying her attention and not her, but shortly afterwords, Orion and her become close. Bulma and her are friends now, she also implied that she and Android 16 might be a item. This led to Bulma giving Orion something for her to give to Android 16 when the "time is right". 
Bulma invited both Orion and Android 16 to her party and tried to calm down Orion after Chi-Chi and Android 18 planted doubts in her brain about Android 16 being taken, this led to Bulma having to leave. She showed concern and happiness when Orion arrived back from her absence after Buu's defeat. She was ecstatic after Orion and Android 16's engagement and wanted to support her friends. 
She was present on the trip to get Orion a dress and upon getting her the dress asked her about kids and her future, she seemed sad about Orion's response. She also got pretty fussy about Orion destroying her dress during her wedding when Arugulot attacked. 
When Orion and Android 16 were sent off to their honeymoon she bid her a farewell, and upon the two arriving back and announcing their pregnancy Bulma was supportive. She even was supportive when Orion was upset about Android 16 being separated from her, and tried her best to take care of her. She later freaked out when Orion went into labor after Vegeta pointed it out. 
Bulma eventually helped Android 16 when Orion was in critical condition after the brutal fight at the end of the New Saiyan Saga.