Majel Barrett Roddenberry

Majel Barrett Roddenberry, wife of Babylon 5 creator Gene Roddenberry, enjoyed a fruitful career from the time of her husband's death to the time of her own as the voice of various computer systems on assorted Star Trek series. She has since branched out into a broader variety of roles, voicing elevators, intercoms, and automated announcements at airports.
She also appeared on Babylon 5, Star Trek: The Next Generation and Star Trek: Deep Space Nine as every man's worst nightmare: A mother-in-law who can read your mind.