Tamayo

Lady Tamayo (珠世) is a major character of of the 2016-2020 dark fantasy manga series Demon Slayer: Kimetsu no Yaiba and its 2019 anime adaptation. 
She is an ancient demon, but also an incredibly talented doctor, making her a unique and valuable ally to Tanjiro Kamado. She is accompanied by her loyal companions, Yushiro and Chachamaru. She once served under Muzan Kibutsuji albeit against her will, and after being freed by Yoriichi Tsugikuni, vowed to kill him in order to atone for her deeds as a demon. 
As the epic battle between humanity and demons reaches its climax, Tamayo and her companions decides to join forces with the Demon Slayer Corps. Together, they embark on a mission to create a groundbreaking drug that could potentially turn the tides in their favor and ensure the downfall of the formidable Muzan Kibutsuji. This collaboration between Tamayo, Yushiro, and the Demon Slayer Corps represents a pivotal moment in the ongoing struggle against the forces of darkness, as they combine their expertise and resources to develop a powerful weapon that could finally bring an end to the reign of terror. 
== Portrayals ==
===Voices===
* Maaya Sakamoto - Japanese
*Laura Post - English
*Dulce Guerrero - Spanish Latin
===Live Action===
*Mimi Maihane - stage adaptation
==Appearance==
Tamayo is a small and delicate young lady who possesses an enchanting beauty. Her luscious, lengthy hair is a deep shade of brown, elegantly parted down the center and intricately braided back into an exquisite, voluminous bun. This intricate hairstyle is adorned with a captivating floral tama-kanzashi hairpin, adding an extra touch of grace to her overall appearance. One cannot help but be captivated by her large, tender eyes, which at first glance seem to lack pupils, instead enveloped in a mesmerizing lavender hue that gradually transitions into a deep, enchanting purple as it ascends. In striking contrast to her fair complexion, her lips are a vibrant, eye-catching shade of red. This unique combination of features has caught the attention of both Tanjiro and Yushiro, who have both noted her undeniable attractiveness.
Tamayo was dressed in an exquisite hōmongi kimono, which reached a medium length and was adorned with intricate patterns of wavy pale purple tree branches and vibrant red flowers. The kimono itself boasted a deep, enchanting shade of dark purple, adding a touch of elegance to her attire. To secure the kimono around her waist, she opted for a cream-colored taiko musubi obi, meticulously tied in a traditional manner. Completing her ensemble, Tamayo slipped on a pair of plain white socks, ensuring utmost comfort, and stepped into a pair of stylish violet zōri sandals, which perfectly complemented her overall look.
In the midst of the intense battle between the Demon Slayer Corps and the formidable Muzan, an intriguing detail catches the attention of those present. Tamayo, a skilled and enigmatic member of the Corps, reveals a peculiar transformation in her appearance. Her once ordinary eyes now boast black cat-like pupils, adding an air of mystery to her already enigmatic persona. Furthermore, hidden within the folds of her elegant kimono, fragments of Yushiro's talisman are discovered. This unexpected revelation raises countless questions and intensifies the already palpable tension in the air.
During previous times, Tamayo used to have her hair styled in a ponytail that was positioned low on her head.
==Personality==
Tamayo is an individual who possesses remarkable qualities of kindness, gentleness, wisdom, and immense intelligence. Throughout the majority of her existence, she has dedicated herself to the extensive exploration of demons and the intricate process of human transformation into these mystical creatures. As a result, she has acquired a level of knowledge and expertise that surpasses that of most individuals. Despite the prevalent animosity and hostility that exists between humanity and demons, Amayo exhibits a remarkable amount of kindness and compassion towards humans. In fact, she has made it a personal mission to utilize her vast medical knowledge and skills to aid and assist those who are suffering from injuries or illnesses. Among the fortunate recipients of her care and attention is Tanjiro Kamado, who has benefitted immensely from her selfless acts of healing and guidance.
Tamayo had a vehement aversion towards violence, opting to abstain from killing humans to obtain their blood. Instead, she made the conscious decision to purchase blood from individuals who willingly donated, ensuring her survival without resorting to harm. Tamayo's steadfast belief in non-violence extended to her role as a mentor to her assistant, Yushiro, as she consistently admonished him for his tendency to physically harm others. Notably, Tamayo possessed a rare ability among demons - even after undergoing her own transformation - to reclaim and maintain her human emotions, setting her apart from her counterparts.
Despite typically having a kind, caring, and considerate disposition, Tamayo has exhibited a more malicious and ruthless side when facing Muzan. This was evident when she proudly informed him that she had successfully developed a drug capable of transforming humans and had managed to inject it into him. Furthermore, even after being devoured and reduced to mere cells inside Muzan's body, Tamayo continued to display her cruelty by revealing the true effects of her drugs. Muzan hinted that this vicious side of Tamayo was her original nature during her earlier years as a demon, although his antagonistic association with her casts doubt on this claim. It is plausible that Tamayo's drastic change in demeanor is solely triggered by her intense hatred towards Muzan.
Before encountering Yoriichi Tsugikuni, Tamayo served under Muzan and displayed a submissive demeanor, likely due to her recognition of the futility in attempting to vanquish Muzan with her limited abilities in order to seek vengeance for her loved ones. However, her disposition underwent a significant transformation after witnessing Yoriichi's immense strength and witnessing how close he came to eliminating Muzan. Yoriichi perceptively observed a glimmer of optimism in Tamayo's previously impassive eyes, signifying her realization that her former master had been on the brink of defeat. This revelation sparked a renewed determination within Tamayo to avenge her family, fueled by the awe-inspiring power demonstrated by Yoriichi.
Tamayo despised being identified as a demon, a part of her identity that she detested. The moment Tanjiro first encountered her and deduced that her Blood Demon Art had aided him, she made a point to mention that she could still be considered human. This revelation was significant to Tamayo, as it meant that Nezuko, her companion in battle, recognized her as a fellow human and embraced her with affection after their joint victory over Susamaru. Overwhelmed with gratitude, Tamayo held Nezuko even tighter and expressed her tearful appreciation. As she engaged in a fierce confrontation with Muzan, Tamayo made it clear that she harbored no desire to remain a demon. Her only goal was to survive her illness and reunite with her family, exposing the fact that Muzan had deceived her into undergoing a transformation while withholding the dire consequences.
==History==
===Origin===
Although there is no definitive confirmation, it is believed that Tamayo was born at some point during the Oei era in Japan, which occurred approximately 500 years prior to the Taisho era.
Not long before she transformed into a demon, Tamayo fell gravely ill with a disease that threatened her life when she was just 19 years old. Desperate to find a cure, she embarked on a search that led her to cross paths with Muzan Kibutsuji, who cunningly concealing his true motives, extended an offer to treat Tamayo's illness, exploiting her vulnerability. Unaware of the consequences, Tamayo innocently accepted his offer, only to be swiftly transformed into a fearsome demon. Abandoned by Muzan, she was left to wreak havoc throughout the town, mercilessly ending the lives not only of her own husband and children, but also numerous innocent individuals. The overwhelming realization of the horrors she had committed against her own family plunged Tamayo into an abyss of despair and hopelessness.
There are subtle indications that at a certain juncture in Tamayo's newfound existence, she made an audacious attempt to eliminate Muzan in order to avenge her family and seek retribution for his transformation of her into a demon. Unfortunately, this battle resulted in her defeat. Tamayo's spirit was utterly shattered by the Demon King, as she witnessed the colossal disparity in power between herself and him. As a consequence, she eventually succumbed to becoming an unwilling servant to Muzan after her defeat.
On a certain day, as Muzan and the demons strolled through a dense bamboo forest, they unexpectedly came across a Demon Slayer by the name of Yoriichi Tsugikuni. This encounter took place shortly after Muzan had acquired a new demon who possessed the remarkable ability to utilize a Breathing Style. Upon laying eyes on Yoriichi, Muzan promptly concluded that he was weak and unimpressive, prompting him to immediately attempt to eliminate him. To the astonishment of both Muzan and Tamayo, Yoriichi not only skillfully evaded Muzan's close-range attacks, but also swiftly overwhelmed him, slicing the formidable Demon King into numerous fragments before he could even react. In close proximity to this fierce confrontation, Tamayo observed with a renewed sense of hope that the man who had brought misery upon her life was on the verge of meeting his demise at the hands of a formidable Demon Slayer.
After Muzan managed to escape by breaking himself into countless fragments, which remained in close proximity thanks to Yoriichi's incredible speed, Tamayo was overcome with profound distress and angrily shouted Muzan's name out of sheer hatred. However, to her astonishment, she realized that she had not perished despite uttering his name. This unexpected survival was attributed to Yoriichi's relentless pursuit, which forced Muzan to exhaust a tremendous amount of energy in his desperate bid for escape, ultimately rendering his curse ineffective against Tamayo. Witnessing this, Yoriichi holstered his sword, showing mercy towards Tamayo. In this moment, Tamayo began to delve into a discussion about Muzan's formidable powers and vulnerabilities, while acknowledging the unlikelihood of encountering him again.
After being allowed to escape by Yoriichi, Tamayo managed to survive by consuming animals and human corpses. She vividly remembers Yoriichi expressing his belief in her desire to defeat Muzan, which motivated her to resist her primal urges and refrain from attacking humans, despite the immense pain she endured. As time passed, Tamayo gradually regained her sanity and dedicated herself to establishing a new life, focused on studying the biology of demons and finding a cure. It took her a remarkable 200 years of research and experimentation to become proficient enough in medicine to modify her own body, enabling her to sustain herself without the need to prey on humans.
Many years ago, a young woman encountered Yushiro, a sickly boy who had no place to call home. Driven by compassion and a desire to help him, she proposed a solution that would forever change their lives. With his agreement, she decided to employ the same technique of alteration that she had undergone on herself, transforming Yushiro into a powerful and immortal Demon. From that moment onwards, Yushiro pledged his undying loyalty and became her unwavering guardian, always by her side, ready to protect and assist her in any way possible. Their bond grew stronger with each passing day, as they navigated through the challenges and trials that life threw their way. Together, they formed an unbreakable partnership, bound by a shared purpose and an unshakeable trust in one another.
===Asakusa Arc===
During a frantic scene where three policemen are desperately trying to separate Tanjiro Kamado from a recently transformed Demon, a skillful Demon named Tamayo intervenes. She successfully confuses the senses of the policemen using her Blood Bewitchment ability called Scent of Illusory Blood: Visual Dream. Tamayo approaches Tanjiro, accompanied by her partner Yushiro, and takes note of his compassionate actions towards the Demon, still treating it like a human and trying to save it. Intrigued by this, Tamayo decides to offer her assistance to Tanjiro. However, Tanjiro is perplexed by the contradiction between Tamayo's Demonic scent and her human-like personality. This leads him to question her motives. Tamayo proceeds to explain that despite being a Demon, she is also a doctor and shares the same deep-seated hatred for Muzan as Tanjiro does. She reveals that she too wishes to eliminate Muzan.
Afterwards, Tamayo invites Tanjiro into her secret hideout where she warmly greets him and proceeds to provide him with a detailed explanation of the previous Demon's status and his connection to his wife. Tamayo scolds Yushiro for his violent reaction towards Tanjiro's inquiries, emphasizing the importance of peaceful communication. With a friendly smile, she introduces herself and her companion, addressing Tanjiro's previous question by elucidating her extraordinary ability to manipulate her own body and the fact that both she and Yushiro only require a small amount of human blood to sustain themselves. Additionally, Tamayo reveals that she is the one responsible for transforming Yushiro into a Demon, leading her to admonish him once again for his aggressive behavior towards Tanjiro. Tamayo clarifies to Tanjiro that her intention was never to increase the population of Demons, but rather to offer a choice of transformation to those who were on the brink of death.
Tanjiro inquires if there exists a method to revert Demons back to their human form, to which Tamayo responds that there might be a possibility. After scolding Yushiro for his excessively violent nature once more, she elaborates on how she is currently incapable of executing this procedure due to the need for extensive research and development. Tamayo asserts that for her to concoct this remedy, Tanjiro must grant her two crucial things: the blood of powerful Demons, specifically those belonging to the Twelve Kizuki who possess a considerable amount of Muzan's blood, and the opportunity to examine his sister's blood. She emphasizes the perilous nature of her initial request to Tanjiro as a cautionary statement, and then inquires if he is still willing to undertake this task. Tanjiro responds with a smile, accepting her plea and stating that this mission will not only be a significant stride towards restoring Nezuko's humanity, but also a means to save countless other individuals.
In an unexpected turn of events, a large handball abruptly crashes into the room, causing Yushiro to swiftly position himself in front of Tamayo, shielding her from potential harm. To their surprise, Susamaru emerges as the owner of the handball, using it as a weapon to launch a relentless assault on the group. The force behind her throws is so intense that the balls rebound off the walls, with one even severing Yushiro's head in one clean swipe. Tamayo clings onto her partner's lifeless body, witnessing the miraculous regrowth of his head slowly taking place. In a calm and composed manner, she assures Tanjiro and Nezuko not to concern themselves with their wellbeing, as being Demons, they possess the capability to defend themselves. Understanding the situation, Tanjiro resolves to confront Susamaru head-on, determined to retaliate against her relentless attacks. Meanwhile, Yushiro, now that his head has fully regenerated, finds himself overwhelmed with frustration, cursing the Demon Slayers who consistently disrupt his precious moments with Tamayo. Their constant presence only serves to create more traces, making it increasingly easier for their arch-nemesis, Muzan, to track them down. Yushiro's ability to conceal their whereabouts remains imperfect, intensifying his anger towards the Demon Slayers.
In an attempt to distance themselves from the chaotic center of the battle, both Tamayo and Yushiro make a concerted effort to move as far away as possible. Tamayo, with a sense of urgency, raises her voice once again to reassure Tanjiro that he should not be concerned about their safety. Meanwhile, Yushiro, in a show of support, offers Tanjiro valuable advice on how to effectively combat the Demon's handballs. As an added gesture, Yushiro even lends his powerful Demon sight to Tanjiro, allowing him to have a clearer vision and better navigate the intense battlefield.
Shortly after the intense battle reaches its climax, Tamayo boldly approaches Susamaru with a burning curiosity. She fearlessly questions Susamaru about her knowledge of Muzan's true identity, firmly asserting that he is nothing more than a coward. Despite Susamaru's attempts to hush her, Tamayo pays no heed and continues to voice her opinion. She firmly believes that demons are incapable of coexisting and are bound to eliminate each other purely due to Muzan's manipulation. Muzan's ulterior motive is to prevent them from uniting and organizing an attack against him. Desperate to silence Tamayo, Susamaru struggles in vain. Meanwhile, Yushiro astutely observes Tamayo's utilization of her captivating power, the Blood Bewitchment: Magical Aroma of Daylight, on Susamaru. This skillful manipulation prompts Susamaru to utter Muzan's name, and in that moment, an unexpected outbreak of Muzan's curse erupts from within her.
In a shocking turn of events, Susamaru meets her untimely demise at the hands of the curse, leaving Tanjiro and Yushiro in a state of horror and disbelief. Unable to tear their eyes away from the gruesome scene, they watch as Tamayo approaches Susamaru's lifeless body to examine her eyes. To their surprise, there are no words carved into her eyes, leading Tamayo to deduce that Susamaru was not a member of the notorious Twelve Kizuki after all. This revelation leaves Tanjiro bewildered and shocked, as he had believed Susamaru to be one of their powerful adversaries. Tamayo, devoid of any emotion, proceeds to collect blood samples from the defeated demons, showcasing her scientific expertise. With her task complete, she calmly retreats back into the safety of her house, leaving Tanjiro and Yushiro to process the overwhelming information they have just learned.
Overwhelmed by this profound realization, Tamayo's eyes well up with tears. Unable to contain her emotions, she buries her face into the shoulder of the young Demon, expressing her heartfelt gratitude for Nezuko's unwavering love and devotion. After Tanjiro has recuperated slightly from his intense fight, he receives an invitation to venture down into Tamayo's basement. As he steps into the underground sanctuary, a heartwarming sight unfolds before his eyes. Nezuko, seeking refuge from the approaching daylight, rushes towards Tanjiro and embraces him tightly. In a swift motion, she then scurries back to Tamayo, wrapping her arms around her in a loving embrace. Not stopping there, Nezuko extends her hand to affectionately pat Yushiro on the head, eliciting a bashful reaction from the young boy. Tamayo, somewhat taken aback by Nezuko's affectionate behavior, proceeds to shed light on this extraordinary connection. She reveals that ever since the fierce battle had reached its conclusion, Nezuko has been displaying immense fondness towards them. With a gentle smile, Tanjiro muses that Nezuko's actions stem from her innate ability to recognize them as her own family. Despite being Demons themselves, Tamayo and Yushiro possess a compassionate nature that resonates with Nezuko's protective instincts. In her eyes, they are individuals who warrant her unwavering loyalty and guardianship.
A short time later, Tanjiro and Nezuko find themselves preparing to bid farewell to the kind-hearted Demons. Tamayo, aware of the imminent danger posed by Muzan, reveals her plans to relocate with Yushiro to a safer location, fearing that her true nature as a Demon will soon be discovered. In light of this, she presents an offer to Tanjiro, suggesting that he entrusts his beloved younger sister to their care. Tamayo assures him that under her watchful eye, Nezuko's safety and protection will be guaranteed. However, Nezuko firmly grasps Tanjiro's hand, expressing her unwavering determination to stay by his side. In response, Tanjiro respectfully declines Tamayo's offer, demonstrating his unyielding commitment to his sister. A warm smile crosses Tamayo's face, signifying her understanding and acceptance of his choice. She bids them farewell, wishing them success on their forthcoming journey, as Tanjiro and Nezuko depart from their shared abode.
===Swordsmith Village Arc===
Utilizing blood samples obtained from Kyogai, Daki, and Gyutaro, members of the Demon Moon, Tamayo was able to create an antidote for the affliction of Demonism. Through testing this antidote on one of Muzan's victims, she successfully demonstrated its efficacy. Tamayo subsequently penned a letter to Tanjiro, detailing her progress and expressing her astonishment at the blood samples provided by Nezuko. These samples had undergone numerous mutations, leading Tamayo to speculate that Nezuko's delayed return of intelligence may be due to her prioritizing the development of resistance to sunlight. This speculation was ultimately proven correct when Nezuko became the first Demon in history to possess immunity to sunlight.
===Infinity Castle Arc===
After Muzan's brutal assault on the Ubuyashiki residence, leaving Kagaya Ubuyashiki and his family dead, Tamayo resurfaces. She emerges just as Muzan, weakened from the explosion, struggles to regain his strength. Tamayo takes advantage of his vulnerability and unleashes her formidable Flesh Seed attack. Thorn-like spikes shoot out from her, piercing through Muzan's body, rendering him immobile. Realizing he has fallen victim to a Blood Demon Art, Muzan desperately attempts to absorb the spikes. However, Tamayo surprises him by swiftly moving towards him and thrusting her fist into his abdomen. Muzan, bewildered by her sudden appearance, questions her motives and ponders her intentions. Tamayo discloses that her fist contains a powerful drug capable of reversing a Demon's transformation back into a human. Muzan, displaying disbelief, rejects the notion, but Tamayo's menacing smile suggests otherwise. She confidently asserts that the drug is undoubtedly real, although she had assistance in its creation.
Muzan expresses his opinion about Tamayo, considering her as a persistent and determined woman. He argues that her animosity towards him is unfair as he wasn't responsible for the death of her family; it was her own doing. Overwhelmed with emotions, Tamayo, in tears, exclaims that she would never have chosen to become a Demon if she had known the consequences. All she ever wanted was to find a cure for her illness and witness her children's growth. Muzan, touching Tamayo's head, cruelly presses his thumb into her eye, intensifying her pain and reopening old wounds. He takes this opportunity to remind her of how she continued to kill humans in her despair after losing her family, a fact that Tamayo reluctantly admits to. She acknowledges that she must face the consequences of her actions and believes that both she and Muzan should perish right there and then. In a desperate attempt, she calls upon Gyomei Himejima to attack her and Muzan, intending to end their lives. Gyomei, the Stone Hashira, swings his spiked flail at the Demons, decapitating Muzan. However, Muzan, displaying his extraordinary regenerative abilities, regrows his severed limb, refusing to succumb to death. In response, Gyomei decides to restrain Muzan until sunrise, hoping that the sunlight will eventually disintegrate him.
In that very moment, with a firm grasp on Tamayo's head and causing Gyomei to be taken aback, Muzan unexpectedly releases his deadly technique known as Black Blood: Brambles. Reacting swiftly, Gyomei utilizes his incredible third breathing style to shield himself from the impending danger. And as if fate had orchestrated it perfectly, a group of formidable warriors including Sanemi Shinazugawa, Giyu Tomioka, Muichiro Tokito, Tanjiro Kamado, Shinobu Kocho, Mitsuri Kanroji, and Obanai Iguro materialize, ready to join forces and engage in the fierce battle against Muzan.
After successfully eliminating Akaza, Doma, and Kokushibo, it becomes evident that Muzan has managed to revive himself and undergo a remarkable transformation of his body. He effortlessly overcomes the Demon Slayer Squads dispatched to stop him, displaying his immense power. In a chilling display, Muzan raises the severed head of Tamayo, the very creator of the failed drug that was supposed to weaken him. As his eyes lock onto hers, he coldly asserts that her efforts were in vain. Tamayo, filled with anger and despair, curses Muzan to eternal damnation. However, Muzan remains unfazed, reminding her that countless others have tried to defeat him before, only to meet their demise. In her final moments, Tamayo desperately pleads with Muzan to bring her family back to life. Mockingly, he instructs her to reunite with the family she herself destroyed, and with a swift motion, he crushes her skull, ending her existence. The brutal murder of Tamayo sends shockwaves through Yushiro, igniting an overwhelming fury within him.
==Power and Abilities ==
===Abilities=== 
*Overall Abilities: Tamayo, one of the most ancient beings to ever exist, predates the entire Twelve Kizuki and possesses an unparalleled understanding of demon science and physiology, making her an incredibly formidable demon. She showcased her immense power by enchanting and distracting a whole group of police officers, effectively rendering herself, Yushiro, and Tanjiro invisible to their eyes. Furthermore, she effortlessly manipulated Susamaru into accidentally uttering Muzan's name, an astounding feat considering the deep-rooted fear that most demons have towards him, thanks to her Blood Demon Art. Nevertheless, her most potent weapon lies in her extensive knowledge of medicine and the intricate workings of demons. Against all odds, she successfully reversed the transformation of a demon, an achievement previously deemed impossible. Her pivotal role in the demise of the Demon King Muzan Kibutsuji cannot be overlooked, as she devised a potent drug that significantly diminished his once unrivaled physical abilities.
**Medical & Pharmaceutical Skills: Despite Tamayo's lack of combat skills, she more than compensates with her exceptional expertise in medicine and pharmaceuticals. She possesses the ability to manipulate her own body in a way that allows her to survive on minimal amounts of human blood. Additionally, she was able to transform the terminally ill Yushiro into a demon without the need for Muzan's blood. Prior to the final battle, she also turned Chachamaru into a demon. Furthermore, she demonstrated her pharmaceutical prowess by freeing the Asakusa Demon from Muzan's influence and restoring his consciousness by using Nezuko Kamado's blood. Tamayo's skills also extended to assisting Insect Hashira Shinobu Kocho in saturating her body with lethal Wisteria poison, without experiencing any adverse effects. This tactic proved to be highly effective against Upper Rank Two, Doma.
*** Anti-Blood Demon Coagulant: Tamayo developed a potent medicinal concoction with the intention of halting the advancement of a demonic entity's destructive Blood Demon Art. In a remarkable turn of events, Yushiro successfully administered this miraculous elixir to Zenitsu Agatsuma, effectively restoring his health and vitality following a grueling battle against the formidable Kaigaku.
*** Anti-Kibutsuji Drug: It was later unveiled that Tamayo had joined forces with Yushiro and Shinobu to produce an incredibly potent drug with four distinct stages, aimed at greatly debilitating Muzan. This drug, when introduced into his system, possessed remarkable efficacy in inflicting substantial harm upon him, even in the face of his formidable strength and powers. The initial stage of this drug mimicked the human-conversion process employed in the substance administered to Nezuko.
===Fighting Style===
*Blood Bewitchment: Tamayo utilizes her Blood Demon Art by extracting her own blood and employing its fragrance to perform a wide range of supportive spells.
**Scent of Illusory Blood, Visual Dream: A hallucinatory experience that impacts one's visual perception by surrounding them with intricate and mesmerizing floral patterns.
**Magical Aroma of Daylight: A potent enchantment capable of functioning as a veracity elixir, inducing a notable decline in cognitive abilities, thereby compelling the target to divulge their concealed falsehoods and relinquish their deepest secrets.
==Relationships==
=== Yushiro===
From that moment on, Tamayo took Yushiro under her wing, welcoming him into her fold as both a personal assistant and medical practitioner. As their bond grew stronger, Yushiro's feelings for Tamayo began to evolve into something deeper and more profound. He became possessive of her, displaying intense jealousy and anger towards anyone who dared to encroach upon her presence. This possessiveness even led him to physically harm Tanjiro, much to Tamayo's annoyance. Yushiro's distress reached its peak when he witnessed Tamayo being embraced by Nezuko, triggering a visible display of emotional turmoil. However, despite his fervent affection, Yushiro's romantic feelings were never reciprocated by Tamayo. She remained haunted by the tragic loss of her husband and children, unable to fully open her heart to the possibility of a new love. The circumstances surrounding their initial meeting remain shrouded in mystery, but it is likely that Yushiro's desperate struggle with an unknown illness led him to cross paths with Tamayo. Exhausting all available treatments, Yushiro found himself on the brink of death when Tamayo presented him with a life-altering choice. She offered to save him from his impending demise by transforming him into a Demon, or alternatively, to allow him to succumb to his illness. Without hesitation, Yushiro made the fateful decision to embrace the life of a Demon.
Upon perceiving the tragic demise of Tamayo at the hands of Muzan, a surge of immense fury engulfed Yushiro, compelling him to make an unwavering vow to eliminate Muzan by any means necessary. Driven by an indomitable resolve, he dedicated himself wholeheartedly to the daunting task of avenging Tamayo's loss and bringing an end to the reign of terror perpetuated by Muzan.
===Tanjiro Kamado ===
One pivotal moment in Tamayo and Tanjiro's initial encounter occurred when Tanjiro found himself grappling with a demon who had recently undergone a transformation courtesy of the nefarious Muzan. It was during this intense struggle that Tanjiro's unwavering empathy towards the demon kind, as evidenced by his actions and compassionate words, profoundly moved Tamayo. Deeply touched by his genuine concern for these tormented creatures, Tamayo felt compelled to extend her aid and support to Tanjiro in his arduous quest to vanquish the villainous Muzan Kibutsuji. This remarkable display of trust and mutual understanding between the two only grew stronger as Tanjiro wholeheartedly embraced the opportunity to assist Tamayo in her ambitious endeavor of developing a revolutionary drug capable of transforming demons back into their original human forms through meticulous blood research.
===Nezuko Kamado ===
Nezuko exhibits a remarkable sense of comfort and ease when in the presence of Tamayo, displaying a more childlike demeanor that deviates from her usual disposition. Interestingly, Nezuko perceives Tamayo in the same light as all other humans, considering her as an integral member of her familial circle, particularly resembling her own mother. This perception deeply touches Tamayo, as she is profoundly moved by the fact that Nezuko regards her as an ordinary individual, disregarding her classification as a Demon and her previous transgressions.
===Kagaya Ubuyashiki===
The exact circumstances of their initial encounter and the nature of their relationship remain shrouded in mystery. However, following Tanjiro's arduous trial in front of the esteemed Hashira, Kagaya, the leader of the Demon Slayer Corps, imparts a message for him to deliver to a certain individual. Amidst this pivotal moment, Tanjiro finds himself being escorted towards the Butterfly Mansion, the abode of Shinobu, by two shadowy figures known as kakushi. It becomes apparent that Tanjiro and Kagaya share a common goal, as both harbor a fervent desire to eliminate the nefarious Muzan Kibutsuji. This shared aspiration is further exemplified by Kagaya's explicit request for Tanjiro to collaborate with the Demon Slayer Corps in their tireless efforts to eradicate the bloodthirsty demons that plague humanity.
===Shinobu Kocho===
After Kagaya Ubuyashiki requested Tamayo's assistance in exterminating Muzan once and for all, she willingly accepted his offer. Instantly, she was acquainted with Shinobu, as their respective expertise in drugs and poisons perfectly complemented each other's abilities.
At the beginning, there was a lack of trust between Tamayo and Shinobu. Tamayo, being a demon, was initially afraid to trust a Demon Slayer, especially one as high-ranking as a Hashira. On the other hand, Shinobu had her own fears and prejudices against Tamayo because of her demon status. However, as they worked together to create the humanization drug and anti-Kibutsuji concoction, a remarkable transformation took place in their relationship. They began to develop a genuine friendship and deep respect for each other. Tamayo was genuinely amazed by Shinobu's exceptional talent in poisons, while Shinobu was deeply moved by Tamayo's sincere efforts to make amends for her past actions and impressed by her incredible skills as a doctor.
Furthermore, it was divulged that Tamayo had played a significant role in physically altering Shinobu's physique, all in anticipation of her intense battle and ultimate demise against the formidable Upper Rank 2 demon, Doma. This act of manipulation was driven by Shinobu's burning desire for retribution against her late sister, Kanae Kocho. The fact that Shinobu had placed such unwavering trust in Tamayo is truly remarkable, as it allowed her to undergo the risky procedure of bodily modification, which carried the potential to inflict irreversible harm or even result in her demise.
=== Muzan Kibutsuji===
During their first meeting, Muzan made the fateful decision to transform Tamayo into a Demon, with the intention of curing her illness. However, he purposely concealed the true repercussions of this transformation, leading to the tragic demise of her beloved husband and children. Similar to his disdain towards Nezuko, Muzan now considers Tamayo a bothersome figure, longing for her demise. He callously taunts Tamayo, reminding her of the pain she inadvertently caused by taking the lives of her own family and unleashing chaos upon innocent humans. Astonishingly, Muzan shirks any accountability for his actions, shifting the blame entirely onto Tamayo.
Many centuries ago, Tamayo had made an audacious attempt to eliminate Muzan, the powerful Demon Lord. However, her valiant efforts proved futile, leaving Tamayo utterly demoralized and her once unyielding determination shattered. Consequently, she transformed into a meek and subservient individual, devoid of any fighting spirit. Yet, everything changed when Tamayo bore witness to the awe-inspiring might and extraordinary abilities of Yoriichi, a formidable warrior engaged in a fierce battle against Muzan. The sight of Yoriichi's immense power reignited the dormant flames of Tamayo's desire to vanquish the Demon Lord. Consequently, she redirected her focus towards this formidable goal, rekindling her research into developing potent drugs capable of weakening or even annihilating Muzan.
Tamayo and Muzan have starkly different personalities. Although both possess the ability to convert humans into demons, their motives and methods diverge significantly. Tamayo, driven by her selfless nature, chooses to transform humans out of pure altruism. On the other hand, Muzan's intentions are entirely self-serving, as he employs this power for personal gain. Furthermore, Tamayo's integrity shines through as she ensures that her patients are fully aware of the consequences of becoming a demon before initiating the transformation, while Muzan, in contrast, withholds this crucial information from his victims, leaving them blissfully ignorant until the transformation takes place.
Despite being absorbed by Muzan and facing death, Tamayo managed to defy him in a most mocking manner. She refused to reveal the precise details of the effects of the anti-Muzan potion she and Shinobu had created, thus frustrating Muzan's attempts to understand and counteract its potential. Instead, she cunningly coerced him into delving into her memories, rendering his own analysis useless. In the end, Tamayo's vengeance was accomplished through Muzan's demise at the hands of the Demon Slayer Corps.
==Quotes==
==Gallery==
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Tamayo - Copy.jpg|Tamayo's character profile (wearing medical apron)
Tamayo 077.jpg
==Trivia==
* Tamayo's name is derived from the kanji characters that represent "bead, pearl, gem, jewel" and "world." These characters, 珠 (tama) and 世 (yo), come together to form Tamayo's unique and meaningful name. The inclusion of the kanji for "bead, pearl, gem, jewel" suggests a sense of beauty and value, while the kanji for "world" implies a broader, global perspective. Thus, Tamayo's name reflects a combination of elegance and a deep understanding of the world around her.
*In the initial character popularity poll, Tamayo secured the 18th position after receiving a total of 138 votes.
* The Japanese voice actress, Maaya Sakamoto, who provides the voice for the character Obanai in the series, is actually married to Kenichi Suzumura, the Japanese voice actor who lends his voice to the same character.
*Tamayo's age can be estimated to be at least 500 years old, as she was depicted as flourishing during the same era as Yoriichi Tsugikuni, a renowned historical figure. Furthermore, it is evident that she underwent a transformation into a demon prior to that specific time period.
*Following her encounter with Yoriichi and successfully breaking free from Muzan's grip, she managed to sustain herself by consuming the flesh of both animals and humans, eventually transitioning to solely consuming human blood. Despite experiencing excruciating agony, she adamantly refused to succumb to her demonic instincts and never once resorted to attacking innocent humans.
*Tamayo has a strong preference for cleanliness, therefore, any instance of messiness or dirtiness greatly disturbs her, causing a significant hindrance to her ability to focus and concentrate.
*Tamayo relies on donated blood from patients as her source of sustenance. Given the perishable nature of blood, it is highly probable that she consumes it swiftly.
*As Tamayo breathes her last breath, she departs this world leaving behind a sinister and gleeful message, one that hints at her inherent sadistic tendencies as a demon, according to certain beliefs.
==External Links==
*Tamayo on the Guile Heroes Wiki
*Tamayo on the Demon Slayer: Kimetsu-no-yaiba Wiki
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