Lori Luthor

Lori Luthor is a character from the Superboy comics. In New Earth stories, she is the daughter of Lena Luthor, the niece of Lex Luthor and the cousin of Lena Luthor II and Jerry White. During her time in Smallville, she became one of Conner's best friends and a sister figure. 
She lived in a house with Lena, who is paraplegic.
She appeared in at least fifteen comics and was created by  Geoff Johns and Francis Manapul.