Omega

;Astronomical nomenclature
* Omega IV, a planet
** Omega IV native, either the Yangs or the Kohms
** Omega IV virus
* Omega Centus I, a planet
* Omega Cygni, a star
* Omega Leonis, a star
** Omega Leonis sector block
* Omega Sagitta system, a star system
* Omega Sagittarii, a star system
* Omega sector, a star sector
* Omega system, a star system
;Computer files
* "137/Omega", a communications file aboard Baran's mercenary vessel
* "EMH Program AK-1 Diagnostic and Surgical Subroutine Omega 323"
* "Omega one", a file pertaining to the Omega molecule
;Maneuvers
* "Attack pattern Omega", used by Benjamin Sisko against the Klingons; used by Sisko against the Centaur; used by Kathryn Janeway against the Krenim
** "Attack pattern Omega-4", used by Sisko against the Jem'Hadar
* "Auto-destruct sequence Omega", used by Jean-Luc Picard
* "Defense procedure omega", used by Janeway
* "Evasive pattern Omega", used by Sisko to evade the Jem'Hadar; used by Chakotay to evade the Vetar
** "Evasive pattern Omega-1", used by Chakotay to evade the Kazon
** "Evasive pattern Omega-2", used by Janeway to evade the Kazon
** "Evasive pattern Omega-3", used by Janeway to evade the Kazon
** "Evasive pattern Omega-6", used by Tom Paris to evade the Praylor
* Omega Directive, a Starfleet general order
* Omega training mission
* Star Fleet Battle Group Omega
;Miscellaneous nomenclature
* "47-Omega, section 9", a module aboard a Borg cube
* Omega Cluster, a Starfleet award
* Omega constant, a math term
* Omega molecule
* Omega radiation
** Omega radiation therapy
* Omega series, a group of elements on the periodic table
;Personnel codes
* "ECH-Omega-42", used to eject the warp core
* "Janeway-Omega-3"
* "Leyton-1-Omega-47"
* "Omega-327", a personal log security clearance system used by Picard
* "Omega-47", engineering override code used by Hogan and Neelix
* "Riker-Omega-3"
* "Seven of Nine-Omega-Phi-93", used to eject the warp core 
* "Sisko-Omega-17", used to end auto-destruct
* "Torres-Omega-Phi-93", used to eject the warp core
* "Troi-Omega-Omega-31"
;Production references
* Omega Cygni system
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