Indore

Indore the largest city in the Malwa region of Central India and the commercial capital of the central Indian state of Madhya Pradesh. It is situated on the Malwa Plateau, just south of the Satpura Range. Indore is the administrative headquarters of the Indore District and the Indore Division, and formerly served as the capital of the former princely state of Indore and the summer capital of the erstwhile state of Central India. It is currently the largest city in Madhya Pradesh.
It is one of the locationsw from where you can travel by road to Nanded, which is a distance of about 565 kms from Indore and will take about 12 hours driving to reach.
==Travelling from Indore to Nanded==
===By Road from Indore to Nanded===
If you are traveling by road from Indore to Nanded then the best route is as follows:
Indore to Khandwa (130Kms) - You wouldn't enter the Khandwa city but go via bypass to next city
Khandwa to Burhanpur (50Kms)
Burhanpur to National Highway 6 (NH6) (50Kms) 
NH6 to Malkapur (20Kms) - Once on NH6 you would move towards Malkapur
Malkapur to Nandura (18Kms)
Nandura to Khamgaon (30Kms)
Khamgaon to Balapur (30Kms) (You would leave NH6 once you cross Balapur. You would turn right once Balapur bypass road is over)
Balapur to Patur (30Kms)
Patur to Washim (50Kms)
Washim to Hingoli (48Kms)
Hingoli to Nanded (85Kms)
Total distance from Indore to Nanded is around 562 Kms. It takes around 12Hrs to cover this distance. The map is also shown above: