Defence potion

is a potion made by using a sliced mushroom on a vial of panrodon, requiring 1 Herblore, yielding an 3 doses and 25 Herblore experience. 
A dose of defence potion provides a temporary skill boost to defence equal to 3 + 10% of the player's current defence level, rounded down. The effect will diminish over time until it expires completely after approximately 10 minutes.