List of original series episodes

== Season 1 ==
Episode 	Number	Topic 	Guest Star
Gets Lost in Space 	1 	Solar System 	Janet Perlstein
For Lunch 	2 	Digestion 	N/A
Inside Ralphie 	3 	Germs 	Dr. Tennelli
Gets Eaten 	4 	Food Chains 	Fisherwoman
Hops Home 	5 	Habitats 	Bella Li
Meets the Rot Squad 	6 	Decomposition 	Larry the Log-Away Guy
All Dried Up 	7 	Desert Adaptation	Mrs. Terese
In the Haunted House 	8 	Sound 	Ghost of Cornelia C. Contralto II, John Ramon, Mr. Perlstein, Mr. Ramon and Professor Cornelia C. Contralto II
Gets Ready, Set, Dough	9 	Kitchen Chemistry	Nick Tennelli, The Baker and The Boy
Plays Ball 	10 	Forces 	Mr. Tennelli
Goes to Seed 	11 	Seeds 	Mr. Archibald Seedplot
Gets Ants in Its Pants	12 	Ants 	Nick Tennelli
Kicks Up a Storm 	13 	Weather 	N/A
== Season 2 ==
Episode 	Number	Topic 	Guest Star
Blows Its Top 	1 	Volcanoes 	N/A
Flexes Its Muscles 	2 	Body Mechanics 	R.U. Humerus
The Busasaurus 	3 	Dinosaurs 	Dr. Carmina Skeledon
Going Batty 	4 	Bats 	Dr. Tennelli, Mr. Hudson, Mr. Perlstein, Mr. Ramon, Mr. Terese, Mr. Wright, Mrs. Franklin, Mrs. Hudson, Mrs. Li, Mrs. Perlstein and Mrs. Wright
Butterfly and the Bog Beast	5 	Butterflies 	Janet Perlstein
Wet All Over 	6 	Water 	Tiffany
In a Pickle 	7 	Microbes 	N/A
Revving Up 	8 	Engines 	Mr. Junkett
Taking Flight 	9 	Flight 	N/A
Getting Energized 	10 	Energy 	Mikey Ramon
Out of This World 	11 	Space Rocks 	Evan Hudson, Mrs. Hudson and Nick Tennelli
Cold Feet 	12 	Warm/Cold-Blooded 	Harry Herpst
Ups and Downs 	13 	Floating and Sinking	Gerri Poveri, Mrs. Li and William Li
== Season 3 ==
Episode 	Number	Topic 	Guest Star
In a Beehive 	1 	Honeybees 	Mrs. Franklin
In the Arctic 	2 	Heat 	Harry Arm
Spins a Web 	3 	Spiders 	General Araneus and John Ramon
Under Construction	4 	Structures 	Cocker Spaniel Li, Mrs. Li and William Li
Gets a Bright Idea	5 	Light 	Janet Perlstein
Shows and Tells 	6 	Archaeology 	Alex Trebek and Arizona Joan Perlstein
Makes a Rainbow 	7 	Color 	Brian Tennelli and Mr. Ruhle
Goes Upstream 	8 	Migration 	Janet Perlstein
Works Out 	9 	Circulation 	Harry Arm, Janet Perlstein and Mr. Sinew
Gets Planted 	10 	Photosynthesis 	N/A
In the Rainforest 	11 	Rainforest Ecology	Inspector 47 and Nick Tennelli
Rocks and Rolls 	12 	Water Erosion 	Ashley Walker-Club Dupree, Dr. Tennelli, Mr. Hudson, Mr. Perlstein, Mr. Terese, Mrs. Franklin, Mrs. Hudson, Mrs. Perlstein and Nick Tennelli
Holiday Special 	13 	Recycling 	Mr. Perlstein, Mrs. Li, Murph Frizzle and Nick Tennelli
== Season 4 ==
Episode 	Number	Topic 	Guest Star
Meets Molly Cule 	1 	Molecules 	Molly Cule and William Li
Cracks a Yolk 	2 	Eggs 	Mr. Ruhle
Goes to Mussel Beach	3 	Tidal Zones 	Nick Tennelli
Goes on Air 	4 	Air Pressure 	N/A
Gets Swamped 	5 	Wetlands 	Janet Perlstein
Goes Cellular 	6 	Cells 	Mr. Perlstein, Mrs. Perlstein and Nick Tennelli
Sees Stars 	7 	Stars 	Horace Scope and Robbie Tennelli
Gains Weight 	8 	Gravity 	Mr. Ruhle, Mr. Tennelli and Nick Tennelli
Makes a Stink 	9 	Smells 	Dr. Tennelli, Flora Whiff, Grandpa Tennelli and Nick Tennelli
Gets Charged 	10 	Electricity 	Mrs. Ramon and Robbie Tennelli
Gets Programmed 	11 	Computers 	Mikey Ramon, Mr. McClean and Mr. Ruhle
In the City 	12 	City Critters 	Grandpa Wright and Mr. Archibald Seedplot
Takes a Dive 	13 	Coral Reefs and Symbiosis	N/A
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