The Jetsons/Clifford the Big Red Dog

* George as Clifford
* June as Driscoll
* Judy as Cleo
* Elroy as T-Bones
* Astro as Mac
* Orbitty as Wally
* Mr. Spacley as Nathen
* Penny (from The Fairy Odd Parents) as Vicky
* Mr Burns (from The Simpsons) as Mr. Gogswell
* Arthur Spacley as Jerry
* Peter Griffin (from Family Guy) as Charley
* Dexter Mom (from Dexter Laboratory) as Emily Elizabeth
* Rosie the Robot Maid as Kelly
* Arthur Spacley as Mr. Howard
* Emily Scopes as Mrs. Howard
* R.U.D.I (from Wallace and Gromit)  as Moon Machine
* George Mother as Cheesy
* Jane Mom as Mi-A
* Barney Ruddle (from The Flintstones) as K.C.
* Melissa as Frankie