Great One

The Great One or Great One may refer to:
* The Great One (Planet of the Spiders), Queen of the Eight Legs encountered by the Third Doctor
* Queen (The Eight Truths), the new Great One of the Eight Legs, encountered by the Eighth Doctor
* The Great One (The Doctor's Daughter), a deity
* Great One (People of the Trees), deities of the People of the Trees
* King Vampire, who on occasion was referred to as "The Great One"