Question 46 (The Impossible Qatar '22)

Question 46 says, "The final enemy of Mario is:" and the possible options are "Luigi," "Bowser," "Framerules," and "Baby penguins." There's a 10-second bomb as well.
While "Bowser" seems like the obvious option, this isn't correct in this case. Nor is it "baby penguins," no matter how much you enjoy dropping them off the cliff in Super Mario 64.
In the original Super Mario Bros., the game has an internal timer that counts up from 0 to 20 every frame and repeatedly cycles, and the game uses this to time stuff in-game. As a consequence, the game only checks for the end of a level every 21 frames, so speedrunners can only gain or lose time in increments of 21 frames (0.35 seconds). This is called the "21-frame rule" or "framerule," and one framerule is a unit of time of 21 frames. (A better explanation can be found here.)
Framerules limits how fast you can complete a level. It's the "final enemy of Mario" (or at least, the final enemy of the people who speedrun his game) because they are always present. Thus, "Framerules" is the correct answer here.
Category:The Impossible Qatar '22