The horrors of science

In 1963CE a brilliant geneticist - unrivalled for nearly a thousand years - retreated to a remote island and created from almost nothing some two thousand human-animal hybrids.
Incapable of breeding but with partners of like human-animal parentage, the population swelled briefly, persisted weakly for several hundred years, and slowly dwindled to nothingness.
The last of this first iteration - "Moreauvians", named after their creator Rennes Moreau, died in 2514CE. Called "Hawking Bear" by his friends for the vocal synthesis technology he made use of, the massive bear-man had achieved a great deal in his life despite his inability to speak, including a doctorate in law. He died on his 140th birthday, the impressive age an example of the art with which his kind was created - as Hawking Bear lived in an age long before age regression technology.
Now, human-animal hybrids appear very rarely, unfortunate circumstances of unlicensed and poorly executed genetic modification. Most do not survive into adulthood.
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Category:Genetic Engineering