Protein sequence:
MSKSLVIVESPAKAKTINKYLGSQYVVKSSVGHIRDLPTVGSSTGEKAKPISTKGMDAEEKAKIKAEKERNALVKRMGIDPYHDWKANYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGNDDRFSRVVFNEITKNAIKQAFEKPEQLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYWEVAVLTNNQNKQAIRLDVTDYKGKKFDPKNQKEAQSAVDFLNVSDYVVTDLETKPTSSRPRAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMARTYIENHFGAQYLPEKPNFYSSKENAQEAHEAIRPSDIRALPESLEGMEKDAVRLYDLIWCQFLACQMPPAQYDSSTLTVTAGDYTLKAKGRILRFDGWTKVLPQIGKNPEDQELPSVTVSEKLALKEVQPTQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNESFGELMNYDFTANMEDTLDKIASGSVNWKTELNQFFKDFSSQLSKAELDELEGGMRPNSLVETDIKCPTCGRNMAIRTASTGVFLGCTGYALPPKERCKTTINLIPEAELLNVLDESSETKALMDRKRCTKCGTAMDSYVIDAHRKIHICGNNPNCDGYLIEEGSFKIKGYDGPVVECDKCGADMHLKLGRFGKYMGCTNCDNTRKILKNGEVAPPKEEPVHFPELKCEK

Annotated regions:
phrase: QRLYEAGYITYMRT
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site

phrase: MDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYWEVAVLTNNQNKQAIRLDVTDYKGKKFDPKNQKEAQSAVDFLNVSDYVVTDLETKPTSSRPRAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMARTYIENHFGAQYLPEKPNFYSSKENAQEAHEAIRPSDIRALPESLEGMEKDAVRLYDLIWCQFLACQMPPAQYDSSTLTVTAGDYTLKAKGRILRFDGWTKVLPQIGKNPEDQELPSVTVSEKLALKEVQPTQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNESFGELMNYDFTANMEDTLDKIASGSVNWKTELNQFFKDFSSQ
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: KSLVIVESPAKAKTINKYLGSQYVVKSSVGHIRDLPTVGSSTGEKAKPISTKGMDAEEKAKIKAEKERNALVKRMGIDPYHDWKANYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGND
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: ETKPTSSRPRAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMARTYIENHFGAQYLPEKPNFYSSKENAQEAHEAIRPSDIRALPESLEGMEKDAVRLYDLIWCQFLACQMPPAQYDSSTLTVTAGDYTLKAKGRILRFDGWTKVLPQIGKNPEDQELPSVTVSEKLALKEVQPTQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIV
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: KSLVIVESPAKAKTINKYLGSQYVVKSSVGHIRDLPTVGSSTGEKAKPISTKGMDAEEKAKIKAEKERNALVKRMGIDPYHDWKANYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGNDDRFSRVVFNEITKNAIKQAFEK
type: DOMAIN
name: TOPRIM_TopoI
description: DNA topoisomerase 1, TOPRIM domain

phrase: RFSRVVFNEITKNAIKQAFEKPEQLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYW
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: ETKALMDRKRCTKCGTAMDSYVIDAHRKIHICGNNPNCDGYLI
type: DOMAIN
name: TOP1_Znf
description: Topoisomerase I, zinc finger

phrase: KSLVIVESPAKAKTINKYLGSQYVVKSSVGHIRDLPTVGSSTGEKAKPISTKGMDAEEKAKIKAEKERNALVKRMGIDPYHDWKANYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGNDDRFSRVVFNE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: IKCPTCGRNMAIRTASTGVFLGCTG
type: DOMAIN
name: Topo_IA_Znf
description: DNA topoisomerase, type IA, zn finger

phrase: VVECDKCGADMHLKLGRFGKYMGCTNCDNTRKILK
type: DOMAIN
name: Topo_IA_Znf
description: DNA topoisomerase, type IA, zn finger

phrase: LNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEYWEVAVLTNNQNKQAIRLDVTDYKGKKFDPKNQKEAQSAVDFLNVSDYVVTDLETKPTSSRPRAPFITSTLQQTASTRLGFGVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALNMARTYIENHFGAQYLPEKPNFYSSKENAQEAHEAIRPSDIRALPESLEGMEKDAVRLYDLIWCQFLACQMPPAQYDSSTLTVTAGDYTLKAKGRILRFDGWTKVLPQIGKNPEDQELPSVTVSEKLALKEVQPTQHFTKPPARFTEAALVKELEKRGIGRPSTYAAIISTIQERGYVRTENRRFYAEKMGEIVTDRLNESFGELMNYDFTANMEDTLDKIASGSVNWK
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LSAGRVQSVAVKLLVERE
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GIGRPSTYAAIIST
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LYDLIWCQFLACQMPP
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: AGYITYMRT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: IYLATDLDREGEA
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LVIVESPAKAKTINKYLGSQYVVKSSVGHIRDLPTVGSSTGEKAKPISTKGMDAEEKAKIKAEKERNALVKRMGIDPYHDWKANYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGNDDRFSRVVFNE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain