Protein sequence:
MAPTVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVLSVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGENICYEVIDCTGIPKSEVGRRIFRAKFSSVTEKDIMDAMNNLVLPSKDEALAVDARQEIDLKVGVAFTRFQTRYFQGKYGNLDSRVISYGPCQTPTLGFCVQRYQQITTFKPEKFWSLKTYVIKDGNEIQLEWDRKKLFDFDVTVMFQKMVASDGILKVTDISVKEECKARPPGLNTVNLLKVASSALGIGPQTAMHLAERLYTQGFISYPRTESTAYPSSFDFRSALAALAHNPLWSNDVRTLLDTGFVKPKQGHDAGDHPPITPMRLATEEALGTDAWRLYQYICQHFIGTVSPDCRYTRTSIEFTSGGETFHCVGNRVTSKGFTSIMPWLAVSENNIPAYKKGDAVSIHKVDIYEGSTTPPDYLSESELISLMEKNGIGTDASIPVHVNNICERNYVQVNSGRRLVPTPLGTTLIRGYQCIDADLCLPDIRRFIEQQITLIAKGEADHLQVVQHVLQQFMKKYSYFVKKIENMDALFEAQFSPLADSGRLLSKCGKCARYMKYISTQPMRLYCVTCEEVYYLPQNGSIKLYKEIICPLDGFELLLFSMVGPDAKSFPLCPFCYNSPPFEGIDKLFGALKLDDTGKVGKGAGMPCFLCLHPTCKQSMITQGVCACPECTGTLILDPVSAPKWRLYCNRCNCIVLLPHAAHKISTTDKKCPTCESTIIEVDFNKKTTPLKDGATLHEGCILCDELLHSLIEMKHGKSFFMRRGRGRGRGRGRGRGSSRGRRGSSRHDDPKMSFRDF

Annotated regions:
phrase: ERLYTQGFISYPRT
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site

phrase: LVLWLDCDREGEN
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: ISYGPCQTPTLGFCVQRY
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: QGFISYPRT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LYQYICQHFIGTVSPD
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GIGTDASIPVHVNN
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: DEALAVDARQEIDLKVGVAFTRFQTRYFQGKYGNLDSRVISYGPCQTPTLGFCVQRYQQITTFKPEKFWSLKTYVIKDGNEIQLEWDRKKLFDFDVTVMFQKMVASDGILKVTDISVKEECKARPPGLNTVNLLKVASSALGIGPQTAMHLAERLYTQGFISYPRTESTAYPSSFDFRSALAALAHNPLWSNDVRTLLDTGFVKPKQGHDAGDHPPITPMRLATEEALGTDAWRLYQYICQHFIGTVSPDCRYTRTSIEFTSGGETFHCVGNRVTSKGFTSIMPWLAVSENNIPAYKKGDAVSIHKVDIYEGSTTPPDYLSESELISLMEKNGIGTDASIPVHVNNICERNYVQVNSGRRLVPTPLGTTLIRGYQCIDADLCLPDIRRFIEQQITLIAKGEADHLQVVQHVLQQFMKK
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: TVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVLSVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGENICYEVIDCTGIPKSEVGRRIFRAKFSSVTEKDIMDAMNN
type: DOMAIN
name: TOPRIM_TopoIII
description: DNA topoisomerase 3-like, TOPRIM domain

phrase: TVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVLSVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGENICYEVIDCTGIPKSEVGRRIFRAKF
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: KDEALAVDARQEIDLKVGVAFTRFQTRYFQGKYGNLDSRVISYGPCQTPTLGFCVQRYQQITTFKPEKFWSLKTYVIKDGNEIQLEWDRKKLFDFDVTVMFQKMVASDGILKVTDISVKEECKARPPGLNTVNLLKVASSALGIGPQTAMHLAERLYTQGFISYPRTESTAYPSSFDFRSALAALAHNPLWSNDVRTLLDTGFVKPKQGHDAGDHPPITPMRLATEEALGTDAWRLYQYICQHFIGTVSPDCRYTRTSIEFTSGGETFHCVGNRVTSKGFTSIMPWLAVSENNIPAYKKGDAVSIHKVDIYEGSTTPPDYLSESELISLMEKNGIGTDASIPVHVNNICERNYVQVNSGRRLVPTPLGTTLIRGYQCIDADLCLPDIRRFIEQQITLIAKGEADHLQVV
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: TVLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVLSVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGENICYEVIDCTGIPK
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: VLMVAEKPSIALSIASALSGGRMSTRKGSTDVHEFDGMFQGSHAFFKVTSVIGHVLSVDFPPAYQNWEGTDPMDLFVAPVLRSECNPKAHIRRHLAQEARGCTYLVLWLDCDREGENICYEVIDCTGIPKSEVGRRIFRAKF
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: SVKEECKARPPGLNTVNLLKVASSALGIGPQTAMHLAERLYTQGFISYPRTESTAYPSSFDFRSALAALAHNPLWSNDVRTLLDTGFVKPKQGHDAGDHPPITPMRLATEEALGTDAWRLYQYICQHFIGTVSPDCRYTRTSIEFTSGGETFHCVGNRVTSKGFTSIMPWLAVSENNIPAYKKGDAVSIHKVDIYEGSTTPPDYLSESELISLMEKNGIGTDASIPVHVNNICERNYVQVNSGRRLVPTPLGTTL
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: RIFRAKFSSVTEKDIMDAMNNLVLPSKDEALAVDARQEIDLKVGVAFTRFQTRYFQGKYGNLDSRVISYGPCQTPTLGFCVQRYQQITTFKPEKFW
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: DSGRLLSKCGKCARYMKYISTQPMRLYCVTCEEVYYLPQ
type: DOMAIN
name: Zn_ribbon_TOP3B
description: DNA topoisomerase 3-beta, zinc ribbon domain