nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
MEVEEAFQAVGEMGIYQMYLCFLLAVLLQLYVATEAILIALVGATPSYHWDLAELLPNQSHGNQSAGEDQAFGDWLLTANGSEIHKHVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQVYSYRRLGEEALSLQALDPQQCVDKESSLGSESEEEEEFYDADEETQMIK

Annotated regions:
phrase: CFLLAVLLQLYVATEAILIALVGATPSYHWDLAELLPNQSHGNQSAGEDQAFGDWLLTANGSEIHKHVHFSSSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIAQYALLGYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKLKCTFSLTHPANRSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPFIVFGATGLTSGLLSLLLPETL
type: DOMAIN
name: MFS_dom
description: Major facilitator superfamily domain
Protein sequence:
MEFILSLIGSLLLVICVLVSVAFLTLLERKVLGYIQIRKGPNKVGLMGIPQPFCDAIKLFTKEQTYPLLSNYLSYYISPIFSLFLSLFVWMCMPFFVKLYSFNLGGLFFLCCTSLGVYTVMVAGWSSNSNYALLGGLRAVAQTISYEVSLALIGFKILLFSLL

Annotated regions:
phrase: GIPQPFCDAIKLFTK
type: CONSERVED_SITE
name: NADH_UbQ_OxRdtase_su1_CS
description: NADH:ubiquinone oxidoreductase, subunit 1, conserved site
Protein sequence:
MRHYETMFILKPTLVEEEIKSKIEFYREVITKHHGVIETSLDMGMRNLAYEIKKHKRGYYYVAYFKAEPSMIVELERLYRINEDVLRFIVIKYESKKEVEAWHALVDRANKKPSHAKEKHEKTEHTHSHHAEEAESVGSHSE

Annotated regions:
phrase: GMRNLAYEI
type: CONSERVED_SITE
name: Ribosomal_bS6_CS
description: Small ribosomal subunit protein bS6, conserved site
Protein sequence:
MAQKLYAGAKLRELRVKLGLTQKVFAERLGASLPYLNQMENNHRPVSATVVLALAQEFGVDVTKLTTSEAERIVTDMREALADPVFTDSPPLADLRLVASNAPAFARAFLDLHRAYRQTHERLASLDEALGRDEADLRPSPWEEVRDFFHYCDNYLDAVDRAAEHYAAPGGVRRDVFSAAMETLTRAGLDLQISDMPAIRSREGNALRLSARAAAPTQRFQLLHQVALLTQNDLLEATLDLARFQTAEAREIAKIGLANYFAGAALLPYRPFLQAAAETRHDLERLADLFGASIEQVAHRLSTLQRPGAKGVPFFFVRVDQAGTITKRHSATRFQFARFGGACPLWNVHRAFETPGRFLRQLAQTPDGVRYLLLARDVSKPGGSFTAPVRRYAIGLGCEVQHADALVYADGLDLKGSFEPIGISCRICDRQECHQRSVPPLEKRLRVDPDRRGLLPYEIVD

Annotated regions:
phrase: LRELRVKLGLTQKVFAERLGASLPYLNQMENNHRPVSATVVLALAQEFGVDVT
type: DOMAIN
name: Cro/C1-type_HTH
description: Cro/C1-type helix-turn-helix domain

phrase: TLQRPGAKGVPFFFVRVDQAGTITKRHSATRFQFARFGGACPLWNVHRAFETPGRFLRQLAQTPDGVRYLLLARDVSKPGGSFTAPVRRYAIGLGCEVQHADALVYADGLDLKGSFEPIGISCRICDRQECHQRSVPPLEKRLRVDPDRRGLLP
type: DOMAIN
name: ScfR_C
description: Short-chain fatty acyl coenzyme A regulators, C-terminal

phrase: RSREGNALRLSARAAAPTQRFQLLHQVALLTQNDLLEATLDLARFQTAEAREIAKIGLANYFAGAALLPYRPFLQAAAETRHDLERLADLFGASIEQVAHRL
type: DOMAIN
name: IrrE_HExxH
description: IrrE N-terminal-like domain

phrase: GAKLRELRVKLGLTQKVFAERLGASLPYLNQMENNHRPVSATVVLALAQEFGVDVTK
type: DOMAIN
name: Cro/C1-type_HTH
description: Cro/C1-type helix-turn-helix domain

phrase: KLRELRVKLGLTQKVFAERLGASLPYLNQMENNHRPVSATVVLALAQEFGVDVTK
type: DOMAIN
name: Cro/C1-type_HTH
description: Cro/C1-type helix-turn-helix domain

phrase: LRELRVKLGLTQKVFAERLGASLPYLNQMENNHRPVSATVVLALAQEFGVDVTK
type: DOMAIN
name: Cro/C1-type_HTH
description: Cro/C1-type helix-turn-helix domain
Protein sequence:
MVKKVLLINGPNLNLLGTREPEKYGTTTLKDIEMEAHQQVAKHQDAELFTYQNNTEGFIIDRIQEAKQQGVGFIIINAGAYTHTSVGIRDALLGTAIPFIEVHITNVHQREPFRHHSYLSDKAIAVIAGLGVYGYTAAIEYALNY

Annotated regions:
phrase: INGPNLNLLGTREPEKY
type: CONSERVED_SITE
name: DHquinase_II_CS
description: Dehydroquinase, class II, conserved site
Protein sequence:
MVHPYLFLNFFRELLHPLGFSEAGADAVVYTWLIMIGLVVLSIAATKRLQAVPSGLQNFMEVIVGGIENMLVETMGEHGKPFFPLVATLALFILVSNLIGLIPGFFPPTANINTTAACAVVVFVTTHIVGVKHHGAGYIKHFLGPIAWLAPMMFFIEVIGHLSRVISLTLRLFGNMNGHELVLIIFFGLAPFVVPLPMMLMGVLVSFIQAFVFMLLAMIYIQGSLEHAH

Annotated regions:
phrase: SLTLRLFGN
type: ACTIVE_SITE
name: ATP_synth_F0_asu_AS
description: ATP synthase, F0 complex, subunit A, active site
Protein sequence:
MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDFIKQSIKDLPNVEVRSFSGLMVNFARKMGASLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEPQYQYLSASLIKEIVILGGDSSGLISEHVAVALKNKLASV

Annotated regions:
phrase: IYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDFIKQSIKDLPNVEVRSFSGLMVNFARKMGASLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEPQYQYLSASLIK
type: DOMAIN
name: Cyt_trans-like
description: Cytidyltransferase-like domain

phrase: IAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDFIKQSIKDLP
type: DOMAIN
name: Cyt_trans-like
description: Cytidyltransferase-like domain
Protein sequence:
MDQDEGLTAVDNIVTQFNTYEDFLDSQITTVDLYYLEDESLARQLVELGYRGTGEIVKREDFEARKAAINIARQAERTQKKTLTSAGKELHDDFLKALAMREEDNRAGKLSTVIFIRDRNPHGQEVSGYIDYAHRLKSEDFEVYFNGKRRLLPRTTDMSFYNWDSHIAVCNSSPNYQVIADNPEGLLFKYKRDRKILNVDPKAHPGDNSTRIPIQTDLYAHVVLFDHVSRRKT

Annotated regions:
Protein sequence:
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL

Annotated regions:
phrase: MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNL
type: DOMAIN
name: DNA_polIII_beta_N
description: DNA polymerase III, beta sliding clamp, N-terminal

phrase: TLPQATMKRLIEATQFSMAHQDVRYYLNGMLFETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGRFP
type: DOMAIN
name: DNA_polIII_beta_cen
description: DNA polymerase III, beta sliding clamp, central

phrase: RRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPM
type: DOMAIN
name: DNA_polIII_beta_C
description: DNA polymerase III, beta sliding clamp, C-terminal
Protein sequence:
MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRNPSVL

Annotated regions:
phrase: DLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFRN
type: DOMAIN
name: Enolase_C
description: Enolase, C-terminal TIM barrel domain

phrase: IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRH
type: DOMAIN
name: Enolase_N
description: Enolase, N-terminal

phrase: IEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRH
type: DOMAIN
name: Enolase_N
description: Enolase, N-terminal

phrase: LLLKVNQIGSVTE
type: CONSERVED_SITE
name: Enolase_CS
description: Enolase, conserved site

phrase: LILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGDEARFAGHNFR
type: DOMAIN
name: Enolase_C
description: Enolase, C-terminal TIM barrel domain
Protein sequence:
MNNARPIRRALISVSDKTGIVEFAQALANRGVDILSTGGTARLLAEKGISVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDDVMETHGINPIDMVVVNLYPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNAHDYERVVAEMDANEKSLTLETRFDLAIAAFEHTASYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFEKKQDMRYGENSHQAAAFYVEANPEEASVSTARQIQGKALSYNNIADTDAALECVKEFDEPACVIVKHANPCGVALGEDILEAYDRAFKTDPTSAFGGIIAFNRELDAATATAITERQFVEVIIAPSVSAEAVAIVAAKKNLRLLECGEWTTKTTGFDVKRVNGGLLVQDRDQGMVSEDDLKVVSKRQPTAEELKDALFCWKVAKYVKSNAIVYSKGDMTIGVGAGQMSRVYSAKIAGIKAADEGLQVEGCVMASDAFFPFRDGIDAAAEAGIKCVIQPGGSMRDDEVIAAADEHGMAMIFTGMRHFRH

Annotated regions:
phrase: MNNARPIRRALISVSDKTGIVEFAQALANRGVDILSTGGTARLLAEKGISVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDDVMETHGINPIDMVVVNLYPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIV
type: DOMAIN
name: MGS-like_dom
description: Methylglyoxal synthase-like domain

phrase: GIVEFAQALANRGVDILSTGGTARLLAEKGISVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDDVMETHGINPIDMVVVNLYPFAETVAKEGCTLADAVENIDIGGP
type: DOMAIN
name: MGS-like_dom
description: Methylglyoxal synthase-like domain

phrase: GIVEFAQALANRGVDILSTGGTARLLAEKGISVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDDVMETHGINPIDMVVVNLYPFAETVAKEGCTLADAVENIDIGGP
type: DOMAIN
name: MGS-like_dom
description: Methylglyoxal synthase-like domain
Protein sequence:
MLNVVIFGAPGSGKGTQSELIIKEYGLDHISTGDVLRGEMKAETELGKIAKDYIEKGQLVPDELIVDMLANVLDSKKPAKGVIFDGFPRTIPQAKALKKMLNERGTDVSVMLNLQVEEEELIKRLLERGKVSGRSDDNLETIKSRLDVYHTQTAPLADYYVGEGKHVAIKGMGTIEEIFGRIKEAVNNVK

Annotated regions:
phrase: VIFDGFPRTIP
type: CONSERVED_SITE
name: Adenylat_kinase_CS
description: Adenylate kinase, conserved site
Protein sequence:
MAPSSRHPQLQPQPQSMAQIVEYIPDRLYLAAYNVAPTADTPFPYPEEPAPVSPRKRTTRLAAGATPLAKPSRPQPCYFTVDDTLLYNAFHHDFGPLHIGHLYRFAIQFHDILGAKQNKERPIVFYSAADPKSRANAACMLACYMVLIQNWPPHLALAPIAQVDPPLMPFRDAGYSQADYGISVQDVVYGVWKAKEEKCCDLDNFDLDEYERFERVEHGDFNWITPHFLAFASPQHAPVQKITEGSELFPLLPRTIAAVDAHPKLPKPFKNVLKHFSEKNIGLVVRLNSQLYSPSYFEALGIQHLDMIFDDGTCPSLTTVRKFIRLAHETITVRKKGIAVHCKAGLGRTGCLIGAYLIYRHGFTANEVISFMRFMRPGMVVGPQQHWLHLNQGTFREWWVEERIERRLRREMAAANPIPSTPIRAMQKTTLRNGQASTPPNRSPSNRTPLSEVDHDRNNIGVQEDYLPAPTPGQPRKTARDRHHPYQRSISGGAPPEAQYPVEQEADLIAKYTQASGESDEELHLRMRRRKATSQSPARSEKIRSVSQTTAIYTIDNDASHDAENIGSVRSKYVERVPSTPGVLAKVRGSKRQGESPLRAKESGVRKTSGRVGSASHSTSVSAASTARKVSGA

Annotated regions:
phrase: VHCKAGLGRT
type: ACTIVE_SITE
name: Tyr_Pase_AS
description: Protein-tyrosine phosphatase, active site

phrase: PVQKITEGSELFPLLPRTIAAVDAHPKLPKPFKNVLKHFSEKNIGLVVRLNSQLYSPSYFEALGIQHLDMIFDDGTCPSLTTVRKFIRLAHETITVRKKGIAVHCKAGLGRTGCLIGAYLIYRHGFTANEVISFMRFMRPGMVVGPQQHWLHLNQG
type: DOMAIN
name: TYR_PHOSPHATASE_DUAL_dom
description: Dual specificity protein phosphatase domain

phrase: EGSELFPLLPRTIAAVDAHPKLPKPFKNVLKHFSEKNIGLVVRLNSQLYSPSYFEALGIQHLDMIFDDGTCPSLTTVRKFIRLAHETITVRKKGIAVHCKAGLGRTGCLIGAYLIYRHGFTANEVISFMRFMRPGMVVGPQQHWLHLNQGTFREWWV
type: DOMAIN
name: TYR_PHOSPHATASE_DUAL_dom
description: Dual specificity protein phosphatase domain

phrase: SEKNIGLVVRLNSQLYSPSYFEALGIQHLDMIFDDGTCPSLTTVRKFIRLAHETITVRKKGIAVHCKAGLGRTGCLIGAYLIYRHGFTANEVISFMRFMRPGMVVGPQQHW
type: DOMAIN
name: Dual-sp_phosphatase_cat-dom
description: Dual specificity phosphatase, catalytic domain

phrase: NFDLDEYERFERVEHGDFNWITPHFLAFASPQHAPVQKITEGSELFPLLPRTIAAVDAHPKLPKPFKNVLKHFSEKNIGLVVRLNSQLYSPSYFEALGIQHLDMIFDDGTCPSLTTVRKFIRLAHETITVRKKGIAVHCKAGLGRTGCLIGAYLIYRHGFTANEVISFMRFMRPGMVVGPQQHWLHLNQGTFRE
type: DOMAIN
name: CDC14_C
description: Dual-specificity phosphatase CDC14, C-terminal

phrase: EALGIQHLDMIFDDGTCPSLTTVRKFIRLAHETITVRKKGIAVHCKAGLGRTGCLIGAYLIYRHGFTANEVISFMRFMRPGMVVGPQQHWLHLNQGTF
type: DOMAIN
name: Tyr_Pase_cat
description: Protein-tyrosine phosphatase, catalytic

phrase: QIVEYIPDRLYLAAYNVAPTADTPFPYPEEPAPVSPRKRTTRLAAGATPLAKPSRPQPCYFTVDDTLLYNAFHHDFGPLHIGHLYRFAIQFHDILGAKQNKERPIVFYSAADPKSRANAACMLACYMVLIQNWPPHLALAPIAQVDPPLMPFRDAGYSQADYGISVQDVVYGVWKA
type: DOMAIN
name: DSPn
description: Dual specificity/tyrosine protein phosphatase, N-terminal

phrase: RKFIRLAHETITVRKKGIAVHCKAGLGRTGCLIGAYLIYRHGFTANEVISFMRFMRPGMVVGPQQH
type: DOMAIN
name: Tyr_Pase_dom
description: Tyrosine-specific protein phosphatases domain

phrase: SRPQPCYFTVDDTLLYNAFHHDFGPLHIGHLYRFAIQFHDILGAKQNKERPIVFYSAADPKSRANAACMLACYMVLIQNWPPHLALAPIAQVDPPLMPFRDAGYSQADYGISVQDVVYGVWK
type: DOMAIN
name: DSPn
description: Dual specificity/tyrosine protein phosphatase, N-terminal
Protein sequence:
MKQYLDLMQKVLTEGTPKNDRTGTGTISIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRSWPAPDGRHIDQITTVMNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMVAQQCDLQVGDFVWTGGDTHLYSNHLEQTNLQLSREPRPLPKLVIKRKPASIFDYRFEDFEIEGYDPHPGIKAPVAI

Annotated regions:
phrase: QYLDLMQKVLTEGTPKNDRTGTGTISIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRSWPAPDGRHIDQITTVMNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMVAQQCDLQVGDFVWTGGDTHLYSNHLE
type: DOMAIN
name: Thymidate_synth/dCMP_Mease_dom
description: Thymidylate synthase/dCMP hydroxymethylase domain

phrase: KQYLDLMQKVLTEGTPKNDRTGTGTISIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRSWPAPDGRHIDQITTVMNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMVAQQCDLQVGDFVWTGGDTHLYSNHLEQTNLQLSREPRPLPKLVIKRKPASIFDYRFEDFEIEGYDPHPGIKAPVA
type: DOMAIN
name: Thymidate_synth/dCMP_Mease_dom
description: Thymidylate synthase/dCMP hydroxymethylase domain

phrase: RRIIVSAWNVGELDKMALAPCHAFFQFY
type: ACTIVE_SITE
name: Thymidylate_synthase_AS
description: Thymidylate synthase, active site
Protein sequence:
MTTPLKPLDDAATSFARRHIGPSPRDVAAMLETVGAKSVAELMAQTLPGTIRQATPLTLEPALSEVEAIGHMRALAAQNQVFTSLIGQGYSGTIMPAVIQRNILENPAWYTAYTPYQPEISQGRLEALFNFQTMICDLTGLDVANASLLDEGTAAAEAMALAERSARAKTKAFFVDRNVHPQTLAVLRTRAEPLGWQLIVGDPVKDLDGAEVFGGLLQYPETTGALRDPRADIAKLHDKGALAILAADLLALTVIASPGELGADIAIGSAQRFGVPMGYGGPHAAYMAVRDALKRSLPGRIVGLSVDSRGAPAYRLALQTREQHIRREKATSNICTAQVLLAVIAAMYAVYHGPDGLKSIARTVHRRAAVLAAGLRKLGFAPASDSFFDTVLVEAGANCDEIIARAESQRINLGRDGSRLRIALDETTTADVVEAVWRAFGGELSYAAIEAEARDAVPAELKRQRPFLTHPVFHAHRSETEMLRYLRKLADRDLALDRAMIPLGSCTMKLNATTEMIPLTWPEFSSLHPFVPRAQAAGYHTMFADLQDWLCRISGYDAVSLQPNSGAQGEYAGLLAIRGYHAARGEGHRTICLIPSSAHGTNPASAHMVGMEVVVVGCDSNGNVDLADLKAKAELHSAKLAAIMITYPSTHGVFEEHIRDICDIVHAHGGQVYLDGANLNAQVGLSRPGDYGADVSHFNLHKTFCIPHGGGGPGMGPIGVKAHLAPFLPGHPATDAATPSPVGPVSAAPYGSASILTISYIYMLLMGGEGLTRATEIAILNANYVAARLDPHFPVLYRNERGRVAHECIIDPRPLKQTCGVTVDDIAKRLIDYGFHAPTMSFPVAGTLMIEPTESESKAELDRFCDAMIAIRKEIAAVEQGRFTIEASPLRHAPHTVHDIADDDWNRVYRRSEGCFPEGTSRTDKYWCPVGRVDNVYGDRNLVCSCPPIGDYAQAAE

Annotated regions:
phrase: RRHIGPSPRDVAAMLETVGAKSVAELMAQTLPGTIRQATPLTLEPALSEVEAIGHMRALAAQNQVFTSLIGQGYSGTIMPAVIQRNILENPAWYTAYTPYQPEISQGRLEALFNFQTMICDLTGLDVANASLLDEGTAAAEAMALAERSARAKTKAFFVDRNVHPQTLAVLRTRAEPLGWQLIVGDPVKDLDGAEVFGGLLQYPETTGALRDPRADIAKLHDKGALAILAADLLALTVIASPGELGADIAIGSAQRFGVPMGYGGPHAAYMAVRDALKRSLPGRIVGLSVDSRGAPAYRLALQTREQHIRREKATSNICTAQVLLAVIAAMYAVYHGPDGLKSIARTVHRRAAVLAAGLRKLGFAPASDSFFDTVLVEAGANCDEIIARAESQRINLGRDGSRLRIALDETTTADVVEAVWRA
type: DOMAIN
name: GDC-P_N
description: Glycine cleavage system P-protein, N-terminal domain

phrase: SYAAIEAEARDAVPAELKRQRPFLTHPVFHAHRSETEMLRYLRKLADRDLALDRAMIPLGSCTMKLNATTEMIPLTWPEFSSLHPFVPRAQAAGYHTMFADLQDWLCRISGYDAVSLQPNSGAQGEYAGLLAIRGYHAARGEGHRTICLIPSSAHGTNPASAHMVGMEVVVVGCDSNGNVDLADLKAKAELHSAKLAAIMITYPSTHGVFEEHIRDICDIVHAHGGQVYLDGANLNAQVGLSRPGDYGADVSHFNLHKTFCIPHGGGGPGMGPIGVKAHLAPFLP
type: DOMAIN
name: GDC-P_N
description: Glycine cleavage system P-protein, N-terminal domain

phrase: ATEIAILNANYVAARLDPHFPVLYRNERGRVAHECIIDPRPLKQTCGVTVDDIAKRLIDYGFHAPTMSFPVAGTLMIEPTESESKAELDRFCDAMIAIRKEIAAVEQGRFTIEASPLRHAP
type: DOMAIN
name: GDC-P_C
description: Glycine dehydrogenase, C-terminal domain
Protein sequence:
MRIIYKQQTMNNNRRDFIKKLGIATAAIAINPLEAKNLLDTSEPKTTNKPIVLSTWNFGLHANVEAWKVLSKGGKALDAVEKGVRLVEDDPTERSVGYGGRPDRDGRVTLDACIMDENYNIGSVACMEHIKNPISVARAVMEKTPHVMLVGDGALEFALSQGFKKENLLTAESEKEWKEWLKTSQYKPIVNIENHDTIGMIALDAQGNLSGACTTSGMAYKMHGRVGDSPIIGAGLFVDNEIGAATATGHGEEVIRTVGTHLVVELMNQGRTPQQACKEAVERIVKIVNRRGKNLKDIQVGFIALNKKGEYGAYCIQDGFNFAVHDQKGNRLETPGFALK

Annotated regions:
phrase: NRRDFIKKLGIATAAIA
type: CONSERVED_SITE
name: TAT_signal_bac_arc
description: Twin-arginine translocation pathway, signal sequence, bacterial/archaeal
Protein sequence:
MRLVFLGPPGAGKGTQSTRLQQKFNIPQLSTGDMLRAAVKAGTPVGLKAKAIMDAGGLVPDEVVVGIIADRIDEPDAKEGFILDGFPRTVKQAEALADILIKKNMKLDAVIELKVDDKALLARIENRAQESLAKGETIRADDNPEAFKKRLESYHAQTAPVSAFYAGKGALKAVDGMAPIDDVSAAIEKALAF

Annotated regions:
phrase: FILDGFPRTVK
type: CONSERVED_SITE
name: Adenylat_kinase_CS
description: Adenylate kinase, conserved site
Protein sequence:
MSTTTVTNHTDTIVALASPQGIGAIGVIRLSGPQAFDITSSVFPSKNIAAVPTHTVHVGNIEDEGRILDEVVVTVFKGPKSFTKEDVVEISCHGSTFIVKELLQLLLRKGARHAKPGEFTMRAFLNGRFDLAQAEAVADLISSDSHASHQVALQQMRGGFSDEIRKLREQLIHFASMVELELDFSEEDVEFADRTQLRKLIHEIKRVIDRLIHSFSLGNVIKNGVPTVIIGKPNAGKSTLLNTLLNEEKAIVSEIAGTTRDFIEDELNVEGITFRFIDTAGLREATDAIEAMGVKRTREKMTQASLVIYLFDVKSTSERELIRDLEELKALKAPFLVVGNKIDKREDAIITTFRNIDGIIYISAKQNIGIEELKQNLLEIIQYESFKQNDTLVTNMRHYESLRETRKALDEVLTGMDSQVPGDLLAQDIRQSLFHLGEITGDISTDDLLDNIFSKFCIGK

Annotated regions:
phrase: KNGVPTVIIGKPNAGKSTLLNTLLNEEKAIVSEIAGTTRDFIEDELNVEGITFRFIDTAGLREATDAIEAMGVKRTREKMTQASLVIYLFDVKSTSERELIRDLEELKALKAPFLVVGNKIDKREDAIITTFRNIDGIIYISAKQNIGIEELKQNLLEI
type: DOMAIN
name: G_TrmE
description: TrmE-type guanine nucleotide-binding domain

phrase: TIVALASPQGIGAIGVIRLSGPQAFDITSSVFPSKNIAAVPTHTVHVGNIEDEGRILDEVVVTVFKGPKSFTKEDVVEISCHGSTFIVKELLQLLLRKGARHAKPGEFTMRAFLNG
type: DOMAIN
name: GTP-bd_TrmE_N
description: GTP-binding protein TrmE, N-terminal

phrase: GVPTVIIGKPNAGKSTLLNTLLNEEKAIVSEIAGTTRDFIEDELNVEGITFRFIDTAGLREATDAIEAMGVKRTREKMTQASLVIYLFDVKSTSERELIRDLEELKALKAPFLVVGNKIDKREDAIITTFRNIDGIIYISAKQNIGIEELKQNLLEII
type: DOMAIN
name: G_TrmE
description: TrmE-type guanine nucleotide-binding domain

phrase: VIIGKPNAGKSTLLNTLLNEEKAIVSEIAGTTRDFIEDELNVEGITFRFIDTAGLREATDAIEAMGVKRTREKMTQASLVIYLFDVKSTSERELIRDLEELKALKAPFLVVGNKIDKREDAIITTFRNIDGIIYISAKQNIGIEELK
type: DOMAIN
name: Small_GTP-bd
description: Small GTP-binding domain

phrase: VIIGKPNAGKSTLLNTLLNEEKAIVSEIAGTTRDFIEDELNVEGITFRFIDTAGLREATDAIEAMGVKRTREKMTQASLVIYLFDVKSTSERELIRDLEELKALKAPFLVVGN
type: DOMAIN
name: GTP-bd
description: GTP binding domain

phrase: LAQAEAVADLISSDSHASHQVALQQMRGGFSDEIRKLREQLIHFASMVELELDFSEEDVEFADRTQLRKLIHEIKRVIDRLIHSFSLGNVIKNGVPTVIIGKPNAGKSTLLNTLLNEEKAIVSEIAGTTRDFIEDELNVEGITFRFIDTAGLREATDAIEAMGVKRTREKMTQASLVIYLFDVKSTSERELIRDLEELKALKAPFLVVGNKIDKREDAIITTFRNIDGIIYISAKQNIGIEELKQNLLEIIQYESFKQNDTLVTNMRHYESLRETRKALDEVLTGMDSQVPGDLLAQDIRQSLFHLGEITGDISTDDLLDNIFSKF
type: DOMAIN
name: MnmE_helical
description: MnmE, helical domain

phrase: IVALASPQGIGAIGVIRLSGPQAFDITSSVFPSKNIAAVPTHTVHVGNIEDEGRILDEVVVTVFKGPKSFTKEDVVEISCHGSTFIVKELLQLLLRKGARHAKPGEFTMRAFLN
type: DOMAIN
name: GTP-bd_TrmE_N
description: GTP-binding protein TrmE, N-terminal
Protein sequence:
MCRVMKASFSRKVKLELCLLSDCALLSSSSAPTNELSGTNLEAHINESPDPNALVGVIIERSPSDSTQTNEFKGATKETLTIETPHSSECKGAGLLSPVSKSMLERLSKFEVEDAENVASYDTKIKKIVRSIVSSFAFGIFGVFLVLLDVTLLLADLIFNDSKLYIPLVYRSISLAIALFFLMDVLLRVFVEGRQHYFSDLLNVLDTAIIVTPLLVDVVYIFFDIKFLRNIPRWIHLVRLLRLIILIRIFHLIHQKRELEKLMRRLVSENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHPNHYRVYNLCSERAYDPKYFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDPANIVAIHCKGGKGRTGTMICAFLIASEIFLTAEESLYYFGERRTDKTNSSKFQGVETPSQNRYVGYFAQVKHLYNWNLPPRRILFIKRFIIYSIRGVGTGGVCDLKVRIVMEKKVVFSSTSLGNCSILHDIETDRVLIDVFSGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQSNRHILHSFRLVFT

Annotated regions:
phrase: RRILFIKRFIIYSIRGVGTGGVCDLKVRIVMEKKVVFSSTSLGNCSILHDIETDRVLIDVFSGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQSNRHILHSFRLVF
type: DOMAIN
name: Tensin_C2-dom
description: Tensin phosphatase, C2 domain

phrase: PPRRILFIKRFIIYSIRGVGTGGVCDLKVRIVMEKKVVFSSTSLGNCSILHDIETDRVLIDVFSGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQSNRHILH
type: DOMAIN
name: Tensin_C2-dom
description: Tensin phosphatase, C2 domain

phrase: SENKRRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHPNHYRVYNLCSERAYDPKYFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDPANIVAIHCKGGKGRTGTMICAFLIASEIFLTAEESLYYFGERRTDKTNSSKFQGVETPSQNRYVGYFAQ
type: DOMAIN
name: PTP_VSP_TPTE
description: TPTE, protein tyrosine phosphatase-like catalytic domain

phrase: PPRRILFIKRFIIYSIRGVGTGGVCDLKVRIVMEKKVVFSSTSLGNCSILHDIETDRVLIDVFSGPPLYDDVKVQFFSSNLPKYYDNCPFFFWFNTSFIQSNRHILHSFRLV
type: DOMAIN
name: Tensin_C2-dom
description: Tensin phosphatase, C2 domain

phrase: HEMVVFTKEVNEWMAQDPANIVAIHCKGGKGRTGTMICAFLIASEIFLTAEESLYYFGER
type: DOMAIN
name: Tyr_Pase_dom
description: Tyrosine-specific protein phosphatases domain

phrase: RRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHPNHYRVYNLCSERAYDPKYFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDPANIVAIHCKGGKGRTGTMICAFLIASEIFLTAEESLYYFGERRTDKTNSSKFQGVETPSQNRYVGYFAQVKHL
type: DOMAIN
name: Tensin_phosphatase
description: Tensin-type phosphatase domain

phrase: IHCKGGKGRT
type: ACTIVE_SITE
name: Tyr_Pase_AS
description: Protein-tyrosine phosphatase, active site

phrase: FAFGIFGVFLVLLDVTLLLADLIFNDSKLYIPLVYRSISLAIALFFLMDVLLRVFVEGRQHYFSDLLNVLDTAIIVTPLLVDVVYIFFDIKFLRNIPRWIHLVRLLRLIILIRIFHLIHQKRELEKL
type: DOMAIN
name: Ion_trans_dom
description: Ion transport domain
Protein sequence:
MLKGIHPAISPELLKILAEMGHGDELVLADAHFPAHSLHHNVVRADGISIATLLKGIAPLFEFDAYVAAPLVMMQAVQGDTLDPDVEKRYLEAIQSAVDFVPNLTRIDRFDFYERTKHAYAVVMTGETAKYGNIIIKKGLPLFYNKLEVLKMNRKALSQKIIDTCLEMTRLGLNQGTAGNVSVRYKEGMLITPTGMPYHLITPENIVYVDNNGKHEDGKLPSSEWQFHLAVYQARAEANAVVHNHSLHCAGLSILEKSIPAIHYMVAVGGTDHIPCVPYATFGTYELASYVSEGIKKSKAILLAHHGLIACGENLDKALWLAQEVEVLASWYLKLLATGLDIPLLSREQMQVVLGKFHTYGLRIEE

Annotated regions:
phrase: QKIIDTCLEMTRLGLNQGTAGNVSVRYKEGMLITPTGMPYHLITPENIVYVDNNGKHEDGKLPSSEWQFHLAVYQARAEANAVVHNHSLHCAGLSILEKSIPAIHYMVAVGGTDHIPCVPYATFGTYELASYVSEGIKKSKAILLAHHGLIACGENLDKALWLAQEVEVLASWY
type: DOMAIN
name: Aldolase_II/adducin_N
description: Class II aldolase/adducin N-terminal

phrase: QKIIDTCLEMTRLGLNQGTAGNVSVRYKEGMLITPTGMPYHLITPENIVYVDNNGKHEDGKLPSSEWQFHLAVYQARAEANAVVHNHSLHCAGLSILEKSIPAIHYMVAVGGTDHIPCVPYATFGTYELASYVSEGIKKSKAILLAHHGLIACGENLDKALWLAQEVEVLASWY
type: DOMAIN
name: Aldolase_II/adducin_N
description: Class II aldolase/adducin N-terminal
Protein sequence:
MRVMGILRNYQQWWIWGILGFWMVMICNVVGNNNLWVTVYYGVPVWREAKTTLFCASDAKAYEREVHNVWATHACVPTDPSPQELELPNVTENFNMWKNDMVDQMHEDIINLWDQSLKPCVKLTPLCVTLFCGNVNITKSNASSSDNSNNGTAEKIINEVMRNCSFNVTTEVRDKEKKEYALFYRLDIIPIDKKNNNDNTSDDTSEYRLINCNTSTITQACPKVSFDPIPIHYCAPAGFAILKCNNKTFDGKGPCNNVSTVLCTHGIKPVVSTQLLLNGSLAEQEIVIRSENISNNAKTIIVHLNESVEIECIRPGNNTRKSVRIGPGQAFYATGDIIGNIRQAHCTINATKWNETLIKVGEKLYKQFNNKTIIFAPSSGGDLEITTHSFNCGGEFFYCNTSKLFNSTYPNNSTDNTSDTITLQCRIKQIINMWQEVGRAMYAPPIAGNITCRSNITGLLLTRDGGGKTNSTNETFRPLGGDMRDNWRSELYKYKVVEIKPLGLAPTKAKRRVVDREKRAVGMGALFLGFLGVAGSTMGAASMTLTVQTRQLLSGIVQQQSNLLRAIEAQQHMLQLTVWGIKQLQTRVLAIERYLKDQQLLGMWGCSGKIICTTAVPWNSSWSNKSEAEIWDNMTWMQWEKEIDNYTDKIYKLLEISQIQQEQNEKELLALDKWGNLWTWFSLTNWLWYIRIFIMIVGGLIGLRIIFAVLSIVNRVRQGYSPLSFQTLIPNPRGPDRPGGIEEEGGEQDRDRSVRLVNGFLSLAWDDL

Annotated regions:
phrase: LWVTVYYGVPVWREAKTTLFCASDAKAYEREVHNVWATHACVPTDPSPQELELPNVTENFNMWKNDMVDQMHEDIINLWDQSLKPCVKLTPLCVTLFCGNVNITKSNASSSDNSNNGTAEKIINEVMRNCSFNVTTEVRDKEKKEYALFYRLDIIPIDKKNNNDNTSDDTSEYRLINCNTSTITQACPKVSFDPIPIHYCAPAGFAILKCNNKTFDGKGPCNNVSTVLCTHGIKPVVSTQLLLNGSLAEQEIVIRSENISNNAKTIIVHLNESVEIECIRPGNNTRKSVRIGPGQAFYATGDIIGNIRQAHCTINATKWNETLIKVGEKLYKQFNNKTIIFAPSSGGDLEITTHSFNCGGEFFYCNTSKLFNSTYPNNSTDNTSDTITLQCRIKQIINMWQEVGRAMYAPPIAGNITCRSNITGLLLTRDGGGKTNSTNETFRPLGGDMRDNWRSELYKYKVVEIKPLGLAPTKAKRRVVDREK
type: DOMAIN
name: HIV1_Gp120
description: Human immunodeficiency virus 1, envelope glycoprotein Gp120

phrase: MGAASMTLTVQTRQLLSGIVQQQSNLLRAIEAQQHMLQLTVWGIKQLQTRVLAIERYLKDQQLLGMWGCSGKIICTTAVPWNSSWSNKSEAEIWDNMTWMQWEKEIDNYTDKIYKLLEISQIQQEQNEKELLALDKWGNLWTWFSLTNWLWYIRIFIMIVGGLIGLRIIFAVLSIVNRVRQGYSPLSFQT
type: DOMAIN
name: GP41-like
description: Retroviral envelope protein GP41-like

phrase: VQTRQLLSGIVQQQSNLLRAIEAQQHMLQLTVWGIKQLQTRVLAIERYLKDQQLLGMWGCSGKIICTTAVPWNSSWSNKSEAEIWDNMTWMQWEKEIDNYTDKIYKLLEISQIQQEQNEKELLALD
type: DOMAIN
name: GP41-like
description: Retroviral envelope protein GP41-like