Protein sequence:
MELFIVESPTKAKTIQKFLGKGFLVKATLGHVKDLPEKELGVDLRTLKAKYVYKRGKKKLVEQLKKLSRRSSIVYLGTDPDREGEAIAYFLKKDLEKVNKNIKRAVFYEITPEAIRESIRNAGDVNMNLVYAQFARRILDRLIGYLISPILWKEFKNYKLSAGRVQSPALRLIVEREREIQNFKVKKYYYVKALLRKGSEEFWAIYDYRYENPSDAKIIAKKLEKGYFSVYKVEKKKEKVSPPKPFITSDLQSEANAKFGFSSERTQKLAQELYEKGYITYPRTDSYRMNEKKAKEFMNYIEKKYGKEYVGRLRRFREKATAQGAHECIRPTSLREEIPEREELRLLYDLIFRRTIASLMKEMLLEREKVTVEAITPELKHPVYLVAKGLKIVFDGWSRVYPSEITEEKLPELYEGDLLDLVKTTLEERKTQPPPRYTEGTLIKTLEKLGIGRPSTYATIVKTLKERGYVEVKKKALVPTEIAFQVVEFLMERFPTLMDYKFTAQMEEKLDLVEEGKLNWKSVVYEFMEKIFGKELEMVR

Annotated regions:
phrase: MELFIVESPTKAKTIQKFLGKGFLVKATLGHVKDLPEKELGVDLRTLKAKYVYKRGKKKLVEQLKKLSRRSSIVYLGTDPDREGEAIAYFLKKDLEKVNKNIKRAVFYEITPEAIRESIR
type: DOMAIN
name: TOPRIM_TopoI
description: DNA topoisomerase 1, TOPRIM domain

phrase: QELYEKGYITYPRT
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site

phrase: MELFIVESPTKAKTIQKFLGKGFLVKATLGHVKDLPEKELGVDLRTLKAKYVYKRGKKKLVEQLKKLSRRSSIVYLGTDPDREGEAIAYFLKKDLEKVNKNIKRAVFYE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: EKKKEKVSPPKPFITSDLQSEANAKFGFSSERTQKLAQELYEKGYITYPRTDSYRMNEKKAKEFMNYIEKKYGKEYVGRLRRFREKATAQGAHECIRPTSLREEIPEREELRLLYDLIFRRTIASLMKEMLLEREKVTVEAITPELKHPVYLVAKGLKIVFDGWSRVYPSEITEEKLPELYEGDLLDLVKTTLEERKTQPPPRYTEGTLIKTLEKLGIGRPSTYATIVKTLKERGYVEVKKKALVPTEIAFQV
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: NIKRAVFYEITPEAIRESIRNAGDVNMNLVYAQFARRILDRLIGYLISPILWKEFKNYKLSAGRVQSPALRLIVEREREIQNFKVKKYY
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: ELFIVESPTKAKTIQKFLGKGFLVKATLGHVKDLPEKELGVDLRTLKAKYVYKRGKKKLVEQLKKLSRRSSIVYLGTDPDREGEAIAYFLKKDLEKVNKNIKRAVFYE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: VNMNLVYAQFARRILDRLIGYLISPILWKEFKNYKLSAGRVQSPALRLIVEREREIQNFKVKKYYYVKALLRKGSEEFWAIYDYRYENPSDAKIIAKKLEKGYFSVYKVEKKKEKVSPPKPFITSDLQSEANAKFGFSSERTQKLAQELYEKGYITYPRTDSYRMNEKKAKEFMNYIEKKYGKEYVGRLRRFREKATAQGAHECIRPTSLREEIPEREELRLLYDLIFRRTIASLMKEMLLEREKVTVEAITPELKHPVYLVAKGLKIVFDGWSRVYPSEITEEKLPELYEGDLLDLVKTTLEERKTQPPPRYTEGTLIKTLEKLGIGRPSTYATIVKTLKERGYVEVKKKALVPTEIAFQVVEFLMERFPTLMDYKFTAQMEEKLDLVEEGKLNWKSV
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: MNLVYAQFARRILDRLIGYLISPILWKEFKNYKLSAGRVQSPALRLIVEREREIQNFKVKKYYYVKALLRKGSEEFWAIYDYRYENPSDAKIIAKKLEKGYFSVYKVEKKKEKVSPPKPFITSDLQSEANAKFGFSSERTQKLAQELYEKGYITYPRTDSYRMNEKKAKEFMNYIEKKYGKEYVGRLRRFREKATAQGAHECIRPTSLREEIPEREELRLLYDLIFRRTIASLMKEMLLEREKVTVEAITPELKHPVYLVAKGLKIVFDGWSRVYPSEITEEKLPELYEGDLLDLVKTTLEERKTQPPPRYTEGTLIKTLEKLGIGRPSTYATIVKTLKERGYVEVKKKALVPTEIAFQVVEFLMERFPTLMDYKFTAQMEEKLDLVEEGKLNWKSVVYEFMEKIFG
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: MELFIVESPTKAKTIQKFLGKGFLVKATLGHVKDLPEKELGVDLRTLKAKYVYKRGKKKLVEQLKKLSRRSSIVYLGTDPDREGEAIAYFLKKDLEKVN
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: VYLGTDPDREGEA
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LSAGRVQSPALRLIVERE
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: KGYITYPRT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LYDLIFRRTIASLMKE
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GIGRPSTYATIVKT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central