Protein sequence:
MEKRPLQTSNAANIPSKTIEEMYQKKTQLEHILLRPDTYVGSIEKHTQNLWVYENDEMVHRAVSYVPGLYKIFDEILVNAADNKQRDPSMDSLKVTIDPEANTVSVYNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIFSTEFIIETADGRRLKKYKQVFSNNMGTKCEPVITKCKASENWTKVTFKPDLEKFKMAYLEEDVVALMKKRVLDMAGCFGKTVKVELNGTLIRFKSFRDYADLFLKCAEKSKPMPLPRIHAKVGDRWEICISLSDGQFQQVSFVNSIATIKGGTHVDYITNQITTYIMNKVNKKKKDANVKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTRQASFGSKCDVPESMLKDVEKSGIVDTLLSWADFKQSKDLKKTDGTKTQRLRGCKAEDANEAGGRNSEKCTLILTEGDSAKALAMAGLSVVGRDHYGVFPLRGKLLNVREASSKQIMDNEEIQNIKKILGLQQNKEYTNVKSLRYGHLMIMADQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFTTPVIRASHPNKTITSFYSMPEYEAWKERLGNSATSWKIKYYKGLGTSTPQEGREYFSDLGRHRKDFIWDDELDGNAIELAFSKKKAEGRKIWMRNFEPGTCRDHEAKLINYKDFVNKELILFSRADLFGSFKKKLYKEIKVAQFIGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLKPNGQFGTCNLGGKDHASARYIYTELSPVTRCLFHEHDDKLLEYLNEDGKSIEPNWYMPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNGEELVPMDPWYKGFRGTIEKSAKEGGYIVNGTVTEIDEQTFRITELPIRKWTQDYKQFLESITDGAPNVKDPLIEDFRQNGDDAIVDIEIKMKPEKIATILQEGLFKKFKLTSTISTSNMHLFDAEGNKKFDTPEQILEEFFPLRLDYYEKSKEYILGNLNRLLLILDNKVRFILGVVNGEIIVSNRKKAELLIELKEKGFTPMPRKGKSTKPQVAGANDDDSEEQEDAEPETASQSVSVEGATWGDYDDLLSLPIGTLTLESVQKLLDEKTEKEKEYEILSGTPTTSLWLKDLDEFEKKLDELDLKYAEDDRKRASQGSKKANGFASKPAKKPPQPRKNTKKAKSVEPENDNSSMEIENAVEAAKPAEVAKPKGRAAPKKNIQKEPEDDIQSLQERLAAYNIESSGEKSQAMESEEVQQKAAGKKQNNKRGGAKKKSSTIVLESDSDNEVNDVDDDDDDFEEVQQKAAPVKKGGRKPAAQNAKKAPAKAPAKAPAAPKKRSVGTKQSAGQKLLTDMLQPAEGTGTSPEKKVRKMRESPFNKKSGSILGRAAAAKDISPIADCSAGSASNTPLSEDEVVEIAPQPARARPQRANRTQMKYALSESESEEDSDEDAELSDFEEDDD

Annotated regions:
phrase: TLILTEGDSAKALAMAGLSVVGRDHYGVFPLRGKLLNVREASSKQIMDNEEIQNIKKILGLQQNKEYTNVKSLRYGHLMIMADQDHDGSHIKGLLINFI
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: INYKDFVNKELILFSRADLFGSFKKKLYKEIKVAQFIGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLKPNGQFGTCNLGGKDHASARYIYTELSPVTRCLFHEHDDKLLEYLNEDGKSIEPNWYMPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNGEELVPMDPWYKGFRGTIEKSAKEGGYIVNGTVTEIDEQTFRITELPIRKWTQDYKQFLESITDGAPNVKDPLIEDFRQNGDDAIVDIEIKMKPEKIATILQEGLFKKFKLTSTISTSNMHLFDAEGNKKFDTPEQILEEFFPLRLDYYEKSKEYILGNLNRLLLILDNKVRFILGVVNGEIIVSNRKKAELLIELKEKGFTPMPRKGKSTKPQVAGANDDDSEEQEDAEPETASQSVSVEGATWGDYDDLLSLPIGTLTLESVQKLLDEKTEKEKEYEILSGTPTTSLWL
type: DOMAIN
name: Topo_IIA_dom_A
description: DNA topoisomerase, type IIA, domain A

phrase: CTLILTEGDSAKALAMAGLSVVGRDHYGVFPLRGKLLNVREASSKQIMDNEEIQNIKKILGLQQNKEYTNVKSLRYGHLMIMADQDHDGSHIKGLLINFIHSFWPSLLKVPSFLVEFT
type: DOMAIN
name: TOPRIM_TopoII
description: DNA topoisomerase 2, TOPRIM domain

phrase: LTEGDSAK
type: CONSERVED_SITE
name: TopoIIA_CS
description: DNA topoisomerase, type IIA, conserved site

phrase: LFGSFKKKLYKEIKVAQFIGYVSEHSAYHHGEQSLASTIIGMAQDFVGSNNINLLKPNGQFGTCNLGGKDHASARYIYTELSPVTRCLFHEHDDKLLEYLNEDGKSIEPNWYMPIIPLVLVNGSEGIGTGWSSYIPNYNPREIIANVRRLLNGEELVPMDPWYKGFRGTIEKSAKEGGYIVNGTVTEIDEQTFRITELPIRKWTQDYKQFLESITDGAPNVKDPLIEDFRQNGDDAIVDIEIKMKPEKIATILQEGLFKKFKLTSTISTSNMHLFDAEGNKKFDTPEQILEEFFPLRLDYYEKSKEYILGNLNRLLLILDNKVRFILGVVNGEIIVSNRKKAELLIELKEKGFTPMPRKGKSTKPQVAGANDDDSEEQEDAEPETASQSVSVEGATWGDYDDLLSLPIGTLTLESVQKLLDEKTEKEKEYEILSGTPTTSLWLKD
type: DOMAIN
name: Topo_IIA_dom_A
description: DNA topoisomerase, type IIA, domain A

phrase: GLYKIFDEILVNAADNKQRDPSMDSLKVTIDPEANTVSVYNNGDGVPVEIHQEEKVYVPELIFGHLLTSSNYDDNVKKTTGGRNGYGAKLTNIF
type: DOMAIN
name: HATPase_dom
description: Histidine kinase/HSP90-like ATPase domain

phrase: FTTPVIRASHPNKTITSFYSMPEYEAWKERLGNSATSWKIKYYKGLGTSTPQEGREYFSDLGRHRKDFIWDDELDGNAIELAFSKKKAEGRKIWMRNFEPGTCRDHEAKLINYKDFVNKELILFSRA
type: DOMAIN
name: TOPRIM_C
description: C-terminal associated domain of TOPRIM

phrase: GDRWEICISLSDGQFQQVSFVNSIATIKGGTHVDYITNQITTYIMNKVNKKKKDANVKAHTVKNHLWVFVNSLIDNPAFDSQTKETLTTRQASFGSKCDVPESMLKDVEKSGIVDTLLSWADFKQSKDLK
type: DOMAIN
name: Topo_IIA_bsu_dom2
description: DNA topoisomerase, type IIA, subunit B, domain 2

phrase: CTLILTEGDSAKALAMAGLSVVGRDHYGVFPLRGKLLNVREASSKQIMDNEEIQNIKKILGLQQNKEYTNVKSLRYGHLMIMADQDHDGSHIKGLLINFIHSFWPSLLKVPSFL
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain