Protein sequence:
MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGEAISWHVAEVIKEKNKVKSDDFFKRVAFNEITKKAIIHAVENPRKLDANLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKDAKDLTEKLKSQNFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGDKYLPNSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVASLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPPLKEQEPLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVSLEKKRFMPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAALNNFWSGFNHNIESVNEQKITEIISYVQKALDYHLFSENKESKACPSCKTGELSLKLGKFGAFLACSNYPECTFRKSIVSGNDNNENDGDLAATPNENKVLGTDKDGIEIYLKKGPYGPYVQLGEQEGKVKPKRSPVPASLNQNDITLEMALKLLSLPLKIGIHKDSGEEIMIGYGKFGPYIKYMGKFISIPKKYDFLNLSLDDAMKLIEDNK

Annotated regions:
phrase: QKLYEGVDIGKETIGLITYMRT
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site

phrase: KDGIEIYLKKGPYGPYVQLGEQEGKVKPKRSPVPASLNQNDITLEMALKLLSL
type: REPEAT
name: Toprim_C_rpt
description: Topoisomerase C-terminal repeat

phrase: HKDSGEEIMIGYGKFGPYIKYMGKFISIPKKYDFLNLSLDDAMKLIED
type: REPEAT
name: Toprim_C_rpt
description: Topoisomerase C-terminal repeat

phrase: MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGEAISWHVAEVIKEKNKVKSDDFFKR
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: KLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGEAISWHVAEVIKEKNKVKSDDFFKRVAFNE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: LDANLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKDAKDLTEKLKSQNFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGDKYLPNSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVASLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPPLKEQEPLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVSLEKKRFMPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAA
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: EKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGDKYLPNSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVASLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPPLKEQEPLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVSLEKKRFMPEELGRLV
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: NLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYWDISLKMQNSNNELFTAKLTHVNDQKLEKFSIINEKDAKDLTEKLKSQNFHVDKIEKKQQKRQPQPPFITSSLQQEAARKLGFSAKKTMQIAQKLYEGVDIGKETIGLITYMRTDGVTLSNDAIADIRKLIDKNYGDKYLPNSPRIYKSKVKNAQEAHEAIRPTNITYTPDSLKEKLEKDYYKLYELIWKRTIACQMENVIMDLVVASLASENKEYLAKANGSTIAFDGFYKVYRESVDDEAEEENKMLPPLKEQEPLKTKEIIPNQHFTEPPPRYSEASLVKKLEELGIGRPSTYASILSVLQDRKYVSLEKKRFMPEELGRLVTVFLVGFFKKYVEYDFTAGLENELDEIAAGKLEWKAALNNFWSGFNHN
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: FFKRVAFNEITKKAIIHAVENPRKLDANLVNAQQARRALDYLVGFTLSPLLWRKLPGCKSAGRVQSVALRLICEREDEIERFKSEEYW
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: KSAGRVQSVALRLICERE
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GIGRPSTYASILSV
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: VYLATDPDREGEA
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: IGLITYMRT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LYELIWKRTIACQMEN
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: ACPSCKTGELSLKLGKFGAFLACSNYPECTFRKS
type: DOMAIN
name: Topo_IA_Znf
description: DNA topoisomerase, type IA, zn finger

phrase: MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGEAISWHVAEVIKEKNKVKSDDFFKRVAFNEITKKAIIHAVEN
type: DOMAIN
name: TOPRIM_TopoI
description: DNA topoisomerase 1, TOPRIM domain

phrase: MKLVIVESPAKAKTINKYLGDEFKVIASFGHIRDLPSKKGSVLPDENFAMKYDISDKAGKYVDAIVKDAKKADAVYLATDPDREGEAISWHVAEVIKEKN
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain