nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
MVQASMRSPNMETFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDTQQAMVRRESVVNLENFKKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRTSEDLRNCESDTEENIARRKALHPRRRSSTS

Annotated regions:
phrase: YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPW
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: LGSGQFAIVKKCREKSTGLEYAAKFIK
type: BINDING_SITE
name: Protein_kinase_ATP_BS
description: Protein kinase, ATP binding site

phrase: IAHFDLKPENIM
type: ACTIVE_SITE
name: Ser/Thr_kinase_AS
description: Serine/threonine-protein kinase, active site

phrase: YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPW
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: YDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPW
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain
Protein sequence:
MSGGKGKAGTSEKASTSRSAKAGLTFPVGRVHRLLRKGNYAQRIGSGAPVYLTSVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGDVTIAQGGVLPNIHQNLLPKKSGKGGVKASQEL

Annotated regions:
phrase: AGLTFP
type: CONSERVED_SITE
name: Histone_H2A_CS
description: Histone H2A conserved site

phrase: AGTSEKASTSRSAKAGLTFPVGRVHRLLRKGNYAQRIGSGAPVYLTSVLEYLAAEILELAGNAARDNKKSRIIPRHLQLAI
type: DOMAIN
name: Histone_H2A/H2B/H3
description: Histone H2A/H2B/H3

phrase: EELNKLLGDVTIAQGGVLPNIHQNLLPKKSGK
type: DOMAIN
name: Histone_H2A_C
description: Histone H2A, C-terminal domain
Protein sequence:
MRWIKVMAGLLPMIGSKGADEKDSSQQRRLSRVVVPEHYDLHVKILDAGFCGSVGIRVMISQDVSEIVLNAKELEIRDAGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYNNGLVGLYKSGGPKEVYSTHFEPTDARWVFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSLREEYGDRKIEYFEETCKMSTYLVAFVVGELSYIEDWSKDGVRLRVYGDSSEVEWGRYGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYVPGKSNVEDMKNVAETVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVVSWDVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIERYVGESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEGWISQAGYPVVSVQDCGSSLVLSQSRYSMLGKSDDSLWTIPVVVSWEGKGQERIELRGRETTVRKRSSVYKVNAEYGGFYRVLYDSAGLSGLESRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRISEYYSDSYHVARSGIEKLLRLRSVFYDDAEIVSLIDKKVRKMILPCVGRIDVFDIGTSVESVSMNKYVLSVGVEVGIREAVEKVQELWRRHVEAGEELGELRWIVYKAVVDENLGYMMDKYKNGDTPGMRREVMNGFSGIKREENFLDVVGNLSQFSVEDIGVVIGSISRGGAFRDAMVEYVVSHGEELYLMVHKNAMLYNMIIMSLRHVSGDLIVEKVERFLSGIKHSGSNLSIEKVRNEIQWRRRMRGIREEVLRGLLPEAEK

Annotated regions:
phrase: YKVNAEYGGFYRVLYDSAGLSGLESRIDSLSVVDRVNVIEDVFGLGFGLYGGLEHGLRRISEYYSDSYHVARSGIEKLLRLRSVFYDDAEIVSLIDKKVRKMILPCVGRIDVFDIGTSVESVSMNKYVLSVGVEVGIREAVEKVQELWRRHVEAGEELGELRWIVYKAVVDENLGYMMDKYKNGDTPGMRREVMNGFSGIKREENFLDVVGNLSQFSVEDIGVVIGSISRGGAFRDAMVEYVVSHGEELYLMVHKNAMLYNMIIMSLRHVSGDLIVEKVERFLSGIKHSGSNLSIEKVRNE
type: DOMAIN
name: ERAP1-like_C_dom
description: ERAP1-like C-terminal domain

phrase: VPEHYDLHVKILDAGFCGSVGIRVMISQDVSEIVLNAKELEIRDAGIVVEGARIPGRVVVGEAEKELEVVRIVFPSSLRAGPGYLTMEFCGDYNNGLVGLYKSGGPKEVYSTHFEPTDARWVFPCFDQPDMKATFKISIDAGSKFTVLANTQAIPSLREEYGDRKIEYFEETCKMSTY
type: DOMAIN
name: Aminopeptidase_N-like_N
description: Aminopeptidase N-like , N-terminal domain

phrase: YGLEVGKRCLEYFSEYFGVGYEFPRAGSAKIDMVGIPNFSSGAMENWGLITFRRESLLYVPGKSNVEDMKNVAETVCHELGHMWFGNLVTMSWWDDLWLNEGFATWVSFKGMENIGSVVSWDVWGEFVLWNVVRGMVDDGLGKSHQIRMNVTDPGEIGEIFDSISYCKGASVIRMIERYVGESVFMLGIRRYIKEHMYGNGNAMSLWKAIGEEYGEDISEMVEG
type: DOMAIN
name: Peptidase_M1_dom
description: Peptidase M1, membrane alanine aminopeptidase
Protein sequence:
MKRILLIVGGGIAAYKACELVRLLRKAGHEVRCVLTEGGSHFVMPMTLAALSEDKVYTTLWDLKDEAEMGHIQLSREADLVVVAPATADLLARMAGGIADDLATTLLLATDKPVLAAPAMNVRMWRHAATRRNIDQLRADGVTVMTPDEGAMACGEYGPGRLPEPAAIVAAIEALLTPHVTPLAGRHVLVTAGPTHEPIDPVRYIANRSSGKQGFAIAGALARLGARVTLVAGPVALPTPHGVERIDVETAREMAAAVEHSLPADAAVMVAAVADWRAEDAAAQKIKKAGGGTPTLRLAENPDILATLAHGTRRPRLVIGFAAETEKVLDHAAAKRARKGADWIVANDVSGDVMGGDANTIHIVTVDGVEDWERLPKEAVAARLAERIAEALA

Annotated regions:
phrase: KRILLIVGGGIAAYKACELVRLLRKAGHEVRCVLTEGGSHFVMPMTLAALSEDKVYTTLWDLKDEAEMGHIQLSREADLVVVAPATADLLARMAGGIADDLATTLLLATDKPVLAAPAMNVRMWRHAATRRNIDQLRADGVTVMTPDEGAMACGEYGPGRLPEPAAIVAAI
type: DOMAIN
name: Flavoprotein
description: Flavoprotein

phrase: LAGRHVLVTAGPTHEPIDPVRYIANRSSGKQGFAIAGALARLGARVTLVAGPVALPTPHGVERIDVETAREMAAAVEHSLPADAAVMVAAVADWRAEDAAAQKIKKAGGGTPTLRLAENPDILATLAHGTRRPRLVIGFAAETEKVLDHAAAKRARKGADWIVANDVSGDVMGGDANTIHI
type: DOMAIN
name: DNA/pantothenate-metab_flavo_C
description: DNA/pantothenate metabolism flavoprotein, C-terminal
Protein sequence:
MRVRNRKGAGEMLAENAHIVVENPADFKGSWSERFGNDHPIHIEVGCGKGAFITGMAALHPEINYIAIDMQLSVLSYALDKAIEADLPNVQMMLVDGAALSEYFADGEIDQVYLNFSDPWPKGRHEKRRLTYKSFLATYEKILRPEGEIHFKTDNRGLFEYSLVSLANYGMELKKVWLDLHQDEEFAPQNVMTEYEQKFSQKGQVIYRLEAKFLPKK

Annotated regions:
Protein sequence:
MRVKGIKRNYQLLWKGGILLLGMLMICNTEQLWVTVYYGVPVWKEATTTLFCASDAKAYVTEKHNVWATHACVPTDPNPQEVELKNVTEDFNMWKNNMVEQMHXDIXSLWEQSMKPCVKLTPLCVTLNCTDVKERNANDTTSTTSPPNTSTPSNSSLENNSDIKNCSFNITTSIRDNIKKEHALFYALDVVPIDNSSSYRLXSCNTSVITQACPKISFEPIPIHYCAPAGFAILKCNQKEFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEDVVIRSANFTDNTKTIIVQLNESIVINCTRPNNNTRKSIHMGPGKAFFATGDIIGDIRQAHCNLSRTEWNKALNRIVTKLGEQFKNSTETITFTQSSGGDPEIVMHSFNCGGEFFYCNSTPLFNSTWVRDGNTWRESNRTNSSTSSVNITLPCRIKQIINMWQEVGKAMYAPPIKGLIRCSSNITGILLTRDGGNNNTTNETFRPGGGDMRDNWRSELYKYKVVKIEPLGIAPTRAKRRVVQREKRAVTLGAMFLGFLGAAGSTMGAASLTLTVQARLLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLXIWGCSGKLICTTTVPWNTSWSNKTYDKIWNNMTWMQWEKEIDNYTDLIYTLIEESQNQQEKNEQDLLELDKWASLWNWFDISQWLWYIKIFIMIVGGLIGLRIVFAVLSIVNRVRQGYSPLSFQTHLPAQRGPDRPEGIEEEGGDRDRGRSGLLVDGFLVLFW

Annotated regions:
phrase: VQARLLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLXIWGCSGKLICTTTVPWNTSWSNKTYDKIWNNMTWMQWEKEIDNYTDLIYTLIEESQNQQEKNEQDLLELD
type: DOMAIN
name: GP41-like
description: Retroviral envelope protein GP41-like

phrase: MGAASLTLTVQARLLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARVLAVERYLRDQQLLXIWGCSGKLICTTTVPWNTSWSNKTYDKIWNNMTWMQWEKEIDNYTDLIYTLIEESQNQQEKNEQDLLELDKWASLWNWFDISQWLWYIKIFIMIVGGLIGLRIVFAVLSIVNRVRQGYSPLSFQ
type: DOMAIN
name: GP41-like
description: Retroviral envelope protein GP41-like

phrase: LWVTVYYGVPVWKEATTTLFCASDAKAYVTEKHNVWATHACVPTDPNPQEVELKNVTEDFNMWKNNMVEQMHXDIXSLWEQSMKPCVKLTPLCVTLNCTDVKERNANDTTSTTSPPNTSTPSNSSLENNSDIKNCSFNITTSIRDNIKKEHALFYALDVVPIDNSSSYRLXSCNTSVITQACPKISFEPIPIHYCAPAGFAILKCNQKEFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEDVVIRSANFTDNTKTIIVQLNESIVINCTRPNNNTRKSIHMGPGKAFFATGDIIGDIRQAHCNLSRTEWNKALNRIVTKLGEQFKNSTETITFTQSSGGDPEIVMHSFNCGGEFFYCNSTPLFNSTWVRDGNTWRESNRTNSSTSSVNITLPCRIKQIINMWQEVGKAMYAPPIKGLIRCSSNITGILLTRDGGNNNTTNETFRPGGGDMRDNWRSELYKYKVVKIEPLGIAPTRAKRRVVQREK
type: DOMAIN
name: HIV1_Gp120
description: Human immunodeficiency virus 1, envelope glycoprotein Gp120
Protein sequence:
MIDISLVMLGAGSSTRFGLATKKQWLRTGDDPLWLKATKNISSNYNFKEIIVVSNECEYMSRFASNIKFIQGGSTRQDSLKNALNHISSDYVMVSDIARIDIPDVLIKRLIKDANLADCIVPALKVSDTVAYGSEYINRDELKRIQTPQLSKTNILKQALNSDIIYTDDSSAIAAIGGKVWYVEGDERARKLTYKDDLKLLNIEPPSSDIFCGNGFDVHAFCEGDYLNLAGVKVPFNKAFKAHSDGDVAIHALCDAILGAAGAPDIGQLFPDTDMKFKGIDSKILLERSVEFVRSIGFEIINVDITIICEKPKISPYKDEMAKTIASVMGINRFRVNIKATTSEKLGFTGRGEGVAVMASVNLKYFDWTRV

Annotated regions:
phrase: EPPSSDIFCGNGFDVHAFCEGDYLNLAGVKVPFNKAFKAHSDGDVAIHALCDAILGAAGAPDIGQLFPDTDMKFKGIDSKILLERSVEFVRSIGFEIINVDITIICEKPKISPYKDEMAKTIASVMGINRFRVNIKATTSEKLGFTGRGEGVAVMASVNL
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: IFCGNGFDVHAFCEGDYLNLAGVKVPFNKAFKAHSDGDVAIHALCDAILGAAGAPDIGQLFPDTDMKFKGIDSKILLERSVEFVRSIGFEIINVDITIICEKPKISPYKDEMAKTIASVMGINRFRVNIKATTSEKLGFTGRGEGVAVMASVNLK
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: CGNGFDVHAFCEGDYLNLAGVKVPFNKAFKAHSDGDVAIHALCDAILGAAGAPDIGQLFPDTDMKFKGIDSKILLERSVEFVRSIGFEIINVDITIICEKPKISPYKDEMAKTIASVMGINRFRVNIKATTSEKLGFTGRGEGVAVMASVN
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: GNGFDVHAFCEGDYLNLAGVKVPFNKAFKAHSDGDVAIHALCDAILGAAGAPDIGQLFPDTDMKFKGIDSKILLERSVEFVRSIGFEIINVDITIICEKPKISPYKDEMAKTIASVMGINRFRVNIKATTSEKLGFTGRGEGVAVMASVN
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: SDGDVAIHALCDAIL
type: CONSERVED_SITE
name: MECDP_synthase_CS
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site

phrase: FCGNGFDVHAFCEGDYLNLAGVKVPFNKAFKAHSDGDVAIHALCDAILGAAGAPDIGQLFPDTDMKFKGIDSKILLERSVEFVRSIGFEIINVDITIICEKPKISPYKDEMAKTIASVMGINRFRVNIKATTSEKLGFTGRGEGVAVMASVN
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Protein sequence:
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKVLMITAALPGSGEWGTQREALAFEQAAVAEETELQTLLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE

Annotated regions:
phrase: GQKDKHAVTEQWL
type: CONSERVED_SITE
name: PsdUridine_synth_TruD_CS
description: Pseudouridine synthase TruD, conserved site

phrase: GVPNYFGAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKVLMITAALPGSGEWGTQREALAFEQAAVAEETELQTLLVREKVEAARRAML
type: DOMAIN
name: PsdUridine_synth_TruD_insert
description: Pseudouridine synthase, TruD, insertion domain
Protein sequence:
MKKNENAHKKMWEGRFSEASSKLLEEFNASINFDKNLFEEDIAGSKAHAKMLGICGILKKDESEAIIKGLDEVLAEIRAGKFAFKIEDEDIHMAVEKRLSQIIGAELGGRLHTARSRNDQVALDFKFYVLKKNLEISSLIKELIATLTNLAKNHKDTLMPGYTHFQHAQPVSLSYHLLAYAFMFKRDFERFVSSYERNNLSPLGSAALAGTPHKIDRSIVASELGFADCTQNAMDSVSDRDYALEILFNISVFMTHASRLCEELILWSSQEFGFVSISDAYSTGSSIMPQKKNPDVAELIRGKTGRVNGNLVALLTTMKGLPLAYNKDMQEDKEGVFDSVATILSSATILNEMIKTAKFNEKNMLKATKTGHLSATDLADYLVREKNIPFRTAHFITGKAVAKAESLGLDLSELNKEQLKSVDENLDENAIKFLDLHASKEARTSKGGTANKSVEEQIQILDDWLK

Annotated regions:
phrase: GRFSEASSKLLEEFNASINFDKNLFEEDIAGSKAHAKMLGICGILKKDESEAIIKGLDEVLAEIRAGKFAFKIEDEDIHMAVEKRLSQIIGAELGGRLHTARSRNDQVALDFKFYVLKKNLEISSLIKELIATLTNLAKNHKDTLMPGYTHFQHAQPVSLSYHLLAYAFMFKRDFERFVSSYERNNLSPLGSAALAGTPHKIDRSIVASELGFADCTQNAMDSVSDRDYALEILFNISVFMTHASRLCEELILWSSQEFGFVSISDAYSTGSSIMPQKKNPDVAELIRGKTGRVN
type: DOMAIN
name: Fumarate_lyase_N
description: Fumarate lyase, N-terminal

phrase: LSATDLADYLVREKNIPFRTAHFITGKAVAKAESLGLDLSELNKEQLKSVDENLDENAIKFLDLHA
type: DOMAIN
name: Arg_succ_lyase_C
description: Argininosuccinate lyase, C-terminal

phrase: GSSIMPQKK
type: CONSERVED_SITE
name: Fumarate_lyase_CS
description: Fumarate lyase, conserved site
Protein sequence:
MTDAAAETKRKGGPRRVALVVAAGRGYRLGGDLPKQYLSLGGRPILRHCLATFAAHPDITAVRVVIHPDDRPLYDQAARGLDLLEPVPGGAERQDSVRLGLESVADLDPDQVLIHDAARPFLTPDVVDRVIAALDAHAGTIPAVAQADTLKRVDADGRISGTVDRAGLWRAQTPQGFRFPDLLAAHRAAAGQTLTDDAAVLEAAGGAVWIVPGAERNVKITTTDDLRRAERRFQGPGETRVGSGFDVHAFGPGDHIVLGGIRIPHDQGLMGHSDADVALHTLADAIYGAIAAGDIGRHFPPTDDRWKGAPSDVFLRHAGALVDALGGRIVHLDLTVMCERPKIGPHRAAIAGRIAEILGLDGGRVAVKATTTERLGFTGRGEGMAAQATATVSLPG

Annotated regions:
phrase: TRVGSGFDVHAFGPGDHIVLGGIRIPHDQGLMGHSDADVALHTLADAIYGAIAAGDIGRHFPPTDDRWKGAPSDVFLRHAGALVDALGGRIVHLDLTVMCERPKIGPHRAAIAGRIAEILGLDGGRVAVKATTTERLGFTGRGEGMAAQATATVS
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: RVGSGFDVHAFGPGDHIVLGGIRIPHDQGLMGHSDADVALHTLADAIYGAIAAGDIGRHFPPTDDRWKGAPSDVFLRHAGALVDALGGRIVHLDLTVMCERPKIGPHRAAIAGRIAEILGLDGGRVAVKATTTERLGFTGRGEGMAAQATAT
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: RVGSGFDVHAFGPGDHIVLGGIRIPHDQGLMGHSDADVALHTLADAIYGAIAAGDIGRHFPPTDDRWKGAPSDVFLRHAGALVDALGGRIVHLDLTVMCERPKIGPHRAAIAGRIAEILGLDGGRVAVKATTTERLGFTGRGEGMAAQATAT
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: SDADVALHTLADAIY
type: CONSERVED_SITE
name: MECDP_synthase_CS
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site

phrase: RRAERRFQGPGETRVGSGFDVHAFGPGDHIVLGGIRIPHDQGLMGHSDADVALHTLADAIYGAIAAGDIGRHFPPTDDRWKGAPSDVFLRHAGALVDALGGRIVHLDLTVMCERPKIGPHRAAIAGRIAEILGLDGGRVAVKATTTERLGFTGRGEGMAAQATAT
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: RVGSGFDVHAFGPGDHIVLGGIRIPHDQGLMGHSDADVALHTLADAIYGAIAAGDIGRHFPPTDDRWKGAPSDVFLRHAGALVDALGGRIVHLDLTVMCERPKIGPHRAAIAGRIAEILGLDGGRVAVKATTTERLGFTGRGEGMAAQATAT
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: VLIHDAA
type: CONSERVED_SITE
name: ISPD_synthase_CS
description: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site
Protein sequence:
MAGSAWVSKVSRLLGAFHNTKQVTRGFAGGVQTVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKDLD

Annotated regions:
phrase: NLYGDILSDLCAGLIGGLG
type: CONSERVED_SITE
name: IsoCit/isopropylmalate_DH_CS
description: Isocitrate/isopropylmalate dehydrogenase, conserved site

phrase: TVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNAKCSDFTEE
type: DOMAIN
name: IsoPropMal-DH-like_dom
description: Isopropylmalate dehydrogenase-like domain

phrase: TVTLIPGDGIGPEISASVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPPEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEEASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAENCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAKIEAACFATIKDGKSLTKDLGGNAKCSDFTEE
type: DOMAIN
name: IsoPropMal-DH-like_dom
description: Isopropylmalate dehydrogenase-like domain
Protein sequence:
MKFLLLTVGLALIGAIQAVENIRSKNDLGVEKFVGSWYLREAAKTMEFSIPLFDMDIKEVNLTPEGNLELVLLEKADRCVEKKLLLKKTQKPTEFEIYISSESASYTFSVMETDYDSYFLFCLYNISDREKMACAHYVRRIEENKGMNEFKKILRTLAMPYTVIEVRTRDMCHV

Annotated regions:
phrase: GSWYLREAAKTMEFSIPLFDMDIKEVNLTPEGNLELVLLEKADRCVEKKLLLKKTQKPTEFEIYISSESASYTFSVMETDYDSYFLFCLYNISDREKMACAHYVRRIEENKGMNEFKKILRTLAMPYTVI
type: DOMAIN
name: Lipocln_cytosolic_FA-bd_dom
description: Lipocalin/cytosolic fatty-acid binding domain
Protein sequence:
MHFEAGIEFAQALDHEDPLSRFREEFSIPAQPDGSQEIYLCGNSLGLQPRRARDYVNQELDKWATLGVKGHFDCEFPWMPYHEFLAESSANLVGAHSDEVVMMNSLTVNLHLMMVSFYRPSATRYKIVIEDHAFPSDHYAVESQLRHHGIDPEDGLLLLKPREGEELLRLEDITALIEEQGDSIALLLLPGVQYYTGQVLPMAELTELAHQHGISVGFDLAHAVGNIPLQLHTWNVDFACWCSYKYLNSGPGSVAGCFVHRRHAQNTQLPRFAGWWGHDKQSRFRMENRFQPIPTAEGWQLSNPPILSLAAIRASLDVFSEAGGMGPLRSKSEKLTAYLQFLLKSEVGEYISIITPEDLEQRGCQLSLSCNARHLSGRQLFQRLEEHGVTCDWREPNVIRVAPVPLYNRFADVYRFVEILKAACEE

Annotated regions:
Protein sequence:
MKHAYIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAGEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMSRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIATDEHPRASTTLEGLAKLKGVVKPEGSVTAGNASGINDGAAAVLIASDEAVAQYQLKARAKIIASTTVGIEPRIMGFAPAPAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLGASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIERV

Annotated regions:
phrase: VNRLCGSSLDAIAMAARA
type: ACTIVE_SITE
name: Thiolase_acyl_enz_int_AS
description: Thiolase, acyl-enzyme intermediate active site

phrase: ALCSMCIGVGQGI
type: ACTIVE_SITE
name: Thiolase_AS
description: Thiolase, active site

phrase: YIVDAIRTPFGRYAGGLAAVRADDLGAIPIAALIERNPSVNWAQVDDVIYGCANQAGEDNRNVGRMSALLAGLPVEVPATTVNRLCGSSLDAIAMAARAIKAGEAHLIIAGGVESMSRAPYVMGKSEGAFGRTQKIEDTTMGWRFINPKLKAMYGVDTMPQTAENVAEQFGIQREDQDQFAYTSQQRTAAAQAKGYFAKEIVPVTIPQRKGEPVVIATDEHPRASTTLEGLAKLKGVVKPEGSVTAGNASGINDGAAAVLIAS
type: DOMAIN
name: Thiolase_N
description: Thiolase, N-terminal

phrase: KARAKIIASTTVGIEPRIMGFAPAPAIKKLLKQANLTLDQMDVIELNEAFAAQALACTRDLGLADDDARVNPNGGAIALGHPLGASGARLVTTALNQLEQSGGKYALCSMCIGVGQGIALIIE
type: DOMAIN
name: Thiolase_C
description: Thiolase, C-terminal

phrase: NPNGGAIALGHPLGAS
type: CONSERVED_SITE
name: Thiolase_CS
description: Thiolase, conserved site
Protein sequence:
MGLPVVAIVGRPNVGKSTIFNRLIGERVAIVEDMPGVTRDRLYGKGEWLTHTFHVIDTGGIEFGETDEILTQMRYQAELAIDEADVIIMIADSRTGVTDADVELSRMLNRTGKPVVLAVNKADNPEMRADIYDFYSLGLGEPFPVSGSHGLGLGDMLEEVCQHFPAEDDEEKRDDVIRVSIIGRPNVGKSSLTNAILGEERVIVSEVAGTTRDAIDTPFERDDQSYVLVDTAGMRKRGKVYETTEKYSVMRAMRSIEDSDVVLVVINGEEGIIEQDKKIAGYAHEAGRGVIIIVNKWDAIEKDDKTMQRFTELIREEFKYLDYAPILYVSAKSKQRVHTILPKVNEVAQAHSMRIPTAVLNDLVTDATIRTPPPSDRGKRLKINYATQATVKPPTFILFVNDPELMHFSYERYIENKIREAFVFEGTPVRIWTRKKT

Annotated regions:
phrase: IRVSIIGRPNVGKSSLTNAILGEERVIVSEVAGTTRDAIDTPFERDDQSYVLVDTAGMRKRGKVYETTEKYSVMRAMRSIEDSDVVLVVINGEEGIIEQDKKIAGYAHEAGRGVIIIVNKWDAIEKDDKTMQRFTELIREEFKYLDYAPILYVSAKSKQRVHTILPKVNEVAQAH
type: DOMAIN
name: G_ENGA
description: EngA-type guanine nucleotide-binding (G) domain

phrase: VAIVGRPNVGKSTIFNRLIGERVAIVEDMPGVTRDRLYGKGEWLTHTFHVIDTGGIEFGETDEILTQMRYQAELAIDEADVIIMIADSRTGVTDADVELSRMLNRTGKPVVLAVN
type: DOMAIN
name: GTP-bd
description: GTP binding domain

phrase: RVSIIGRPNVGKSSLTNAILGEERVIVSEVAGTTRDAIDTPFERDDQSYVLVDTAGMRKRGKVYETTEKYSVMRAMRSIEDSDVVLVVINGEEGIIEQDKKIAGYAHEAGRGVIIIVN
type: DOMAIN
name: GTP-bd
description: GTP binding domain

phrase: VSIIGRPNVGKSSLTNAILG
type: DOMAIN
name: GTP-bd
description: GTP binding domain

phrase: VMRAMRSIEDSDVVLVVI
type: DOMAIN
name: GTP-bd
description: GTP binding domain

phrase: IRVSIIGRPNVGKSSLTNAILGEERVIVSEVAGTTRDAIDTPFERDDQSYVLVDTAGMRKRGKVYETTEKYSVMRAMRSIEDSDVVLVVINGEEGIIEQDKKIAGYAHEAGRGVIIIVNKWDAIEKDDKTMQRFTELIREEFKYLDYAPILYVSAKSKQRVHT
type: DOMAIN
name: Small_GTP-bd
description: Small GTP-binding domain

phrase: PVVAIVGRPNVGKSTIFNRLIGERVAIVEDMPGVTRDRLYGKGEWLTHTFHVIDTGGIEFGETDEILTQMRYQAELAIDEADVIIMIADSRTGVTDADVELSRMLNRTGKPVVLAVNKADNP
type: DOMAIN
name: Small_GTP-bd
description: Small GTP-binding domain

phrase: RIPTAVLNDLVTDATIRTPPPSDRGKRLKINYATQATVKPPTFILFVNDPELMHFSYERYIENKIREAFVFEGTPVRIWT
type: DOMAIN
name: KH_dom-like
description: GTPase Der, C-terminal KH-domain-like

phrase: PVVAIVGRPNVGKSTIFNRLIGERVAIVEDMPGVTRDRLYGKGEWLTHTFHVIDTGGIEFGETDEILTQMRYQAELAIDEADVIIMIADSRTGVTDADVELSRMLNRTGKPVVLAVNKADNPEMRADIYDFYSLGLGEPFPVSGSHGLGLGDMLEEVCQHFPAE
type: DOMAIN
name: G_ENGA
description: EngA-type guanine nucleotide-binding (G) domain
Protein sequence:
MISGILASPGIAFGTALLLKEDEIVINRKIINIKNITKEIERFFEGRRKSIQQLTEIKTKTKEKFGEKKESIFEGHIMLLEDEELEQEVISLIKEKNMSAAAATELIIEGQAKALEKLKDEYLKNRAIDVRDIGNRLLKNILNLNIIDLNNINNEVILIAKDLTPSETAQINLKYILGFITDLGSRTSHTSIMARSLEIPAIVGTGNITKIVKNNDFIILDSINNQILINPSHKLINQTEVIKKKYLTKKNQLINLKNLQAITTDGHAIKIGSNIGNVEDIKSAKKNGAECIGLYRTEFLFMGRNCLPDENEQFQAYKTIAELMKNKSVIIRTMDIGGDKDLPYMNLPKEENPFLGWRAIRISMDRKEILHTQLNAILRASAFGKIYILFPMIISVEEIRILKSEVRKLQIQLKNNNIPFDKNIKIGIMIETPASAIIAEYLIKEVDFFSIGTNDLTQYTLAVDRGNDLISHLYNPMNPSVLKLIQQVINVSHTHGKWTGMCGELAGDERATILLLGMGLDEFSMSSISIPKIKEIIRKTSFSSAKKLAQKALTLPTNREILNLVENFVNH

Annotated regions:
phrase: NNEVILIAKDLTPSETAQINLKYILGFITDLGSRTSHTSIMARSLEIPAIVGTGNITKIVKNNDFIILD
type: DOMAIN
name: PEP-util_enz_mobile_dom
description: PEP-utilising enzyme, mobile domain

phrase: GILASPGIAFGTALLLKEDEIVINRKIINIKNITKEIERFFEGRRKSIQQLTEIKTKTKEKFGEKKESIFEGHIMLLEDEELEQEVISLIKEKNMSAAAATELIIEGQAKALEKLKDEYLKN
type: DOMAIN
name: PTS_EIN
description: Phosphotransferase system, enzyme I N-terminal

phrase: DFFSIGTNDLTQYTLAVD
type: CONSERVED_SITE
name: PEP_util_CS
description: PEP-utilising enzyme, conserved site

phrase: ISGILASPGIAFGTALLLKEDEIVINRKIINIKNITKEIERFFEGRRKSIQQLTEIKTKTKEKFGEKKESIFEGHIMLLEDEELEQEVISLIKEKNMSAAAATELIIEGQAKALEKLKDEYLKNRAIDVRDIGNRLLKNILNLNIIDLNNINNEVILIAKDLTPSETAQINLKYILGFITDLGSRTSHTSIMARSLEIPAIVGTGNITKIVKNNDFIILDSINNQILINPSHKLINQTEVIKKKYLTKKNQLINLKNLQAITTDGHAIKIGSNIGNVEDIKSAKKNGAECIGLYRTEFLFMGRNCLPDENEQFQAYKTIAELMKNKSVIIRTMDIGGDKDLPYMNLPKEENPFLGWRAIRISMDRKEILHTQLNAILRASAFGKIYILFPMIISVEEIRILKSEVRKLQIQLKNNNIPFDKNIKIGIMIETPASAIIAEYLIKEVDFFSIGTNDLTQYTLAVDRGNDLISHLYNPMNPSVLKLIQQVINVSHTHGKWTGMCGELAGDERATILLLGMGLDEFSMSSISIPKIKEIIRKTSFSSAKKLAQKALTLPTNREILNLV
type: DOMAIN
name: PTS_EI-like
description: Phosphotransferase system, enzyme I-like

phrase: QLINLKNLQAITTDGHAIKIGSNIGNVEDIKSAKKNGAECIGLYRTEFLFMGRNCLPDENEQFQAYKTIAELMKNKSVIIRTMDIGGDKDLPYMNLPKEENPFLGWRAIRISMDRKEILHTQLNAILRASAFGKIYILFPMIISVEEIRILKSEVRKLQIQLKNNNIPFDKNIKIGIMIETPASAIIAEYLIKEVDFFSIGTNDLTQYTLAVDRGNDLISHLYNPMNPSVLKLIQQVINVSHTHGKWTGMCGELAGDERATILLLGMGLDEFSMSSISIPKIKEIIRK
type: DOMAIN
name: PEP_util_C
description: PEP-utilising enzyme, C-terminal
Protein sequence:
MISYEYPLSERIRTLLRLEDLFRKVAHFGGSEAPLDHHVALLTIFEILEVASRADLKVDLVQELERQRQILLSFRNNPEISEEALAGALYEIEQASTALLSMAGKIGQYLRENEWLMGIRSRAAIPGGVCQFDLPSYHFWLNRDAAERRHDLDAWIMPMTPIRDGIEIVMRLLRSSGRPEQQRARAGTYQLTMAGRVAQMLRVRIPRSEAVVPEISANKYALNIRFMLPETVARPRVAEREITFELTFCTL

Annotated regions:
Protein sequence:
MCEMSEEYRESAPKGPPPPRLGTGDQKCVKCKEGLPVVVIRAGDAFCRDCFKALYVHKFRAMLGKSRLIFPGEKVLLAWSGGPSSSSMVWQVLEGLSRDSAKRLRFVPGVVYIDEGAACGQSPEDRARTLAEVKLALQTTGFPWHAVALEEVFSLPPSALRCSAQEAAGTEGAYKAAVDSFLQQQHALGTNGVERQSQHCAQDPQSPTGPPTTAQTQALSRLFDSVKTLTAKEELLQTLRTHLILHVARNHGYSKVMTGDSCTRLAIKLMTSLALGRGAFLAWDTGFSDERHGDVVVVRPMREHTLKEVAFYNRLFAVPSICTPALDTKAPEKASIHRLMEAFILRLQAQFPSTVSTVYRTSEKLVKAPRAGCAAGPRCLLCMCTLDVDTADSATAFGAQTSHLPQMQTPVTQARAAAGPCCCAGMGGAPGCCKREDPRAQVMEQLCYGCRVNMKDLPSLELLPPYILSEAQLRSQRATAEQEIREYLLGDSEDEAGTGES

Annotated regions:
Protein sequence:
METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAGDQGHMFGYATDETPELMPLSHVLATKIGAKLTEVRKNGTCRWLRPNGKTQVTGEYYNDNGAMVPVRVHTVLISTQHDETVTNDEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFVDTYGTGLIPDKEILKIVKESFDFRPGMMTINLDLKRGGNGRFLKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA

Annotated regions:
phrase: GGGAFSGK
type: CONSERVED_SITE
name: ADOMET_SYNTHASE_CS
description: S-adenosylmethionine synthetase, conserved site

phrase: IGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFVDTYGTGLIPDKEILKIVKESFDFRPGMMTINLDLKRGGNGRFLKTAAYGHFGRDDPDFTW
type: DOMAIN
name: S-AdoMet_synt_C
description: S-adenosylmethionine synthetase, C-terminal

phrase: IGAGDQGHMFGYATDETPELMPLSHVLATKIGAKLTEVRKNGTCRWLRPNGKTQVTGEYYNDNGAMVPVRVHTVLISTQHDETVTNDEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGR
type: DOMAIN
name: S-AdoMet_synt_central
description: S-adenosylmethionine synthetase, central domain

phrase: FLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQS
type: DOMAIN
name: S-AdoMet_synt_N
description: S-adenosylmethionine synthetase, N-terminal

phrase: GAGDQGHMFG
type: CONSERVED_SITE
name: ADOMET_SYNTHASE_CS
description: S-adenosylmethionine synthetase, conserved site
Protein sequence:
MLNEFINFETISRSDWQRFYQEDQVSLTPEELESIRSLNDKIDVQEVRDIYLPLINLIRIYHRAAEDLTFSKGIFLQKAQANRPFIIGISGSVAVGKSTTSRLLQLLLQRTFPKAKVDMVTTDGFLFPNQVLIDKGILNRKGFPESYDMPLLLNFLDTVKNGGDVNIPVYSHEIYDIVPGLTQKISQPNFLIVEGINVFQNPINQRLYMSDYFDFSIYIDADVKNIKTWYLERFQTLLELARKDENNYYHRFTKFTKEEALSLAQKTWKEINLVNLENYIEPTRNRAELILHKGDSHKIDLIHLKK

Annotated regions:
phrase: IIGISGSVAVGKSTTSRLLQLLLQRTFPKAKVDMVTTDGFLFPNQVLIDKGILNRKGFPESYDMPLLLNFLDTVKNGGDVNIPVYSHEIYDIVPGLTQKISQPNFLIVEGINVFQNPINQRLYMSDYFDFSIYIDADV
type: DOMAIN
name: PRK/URK
description: Phosphoribulokinase/uridine kinase
Protein sequence:
MGGKWSKSSIVGWPAIRERMRRTSPTTPAAVGVGAASRDLERHGAITSSNTAQTNADCAWLEAQEEEGEVGFPVRPQVPLRPMTYKAAVDLSHFLKEKGGLEGLVWSRKRQDILDLWVYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPLEPEEVEEANEGENNSLLHPVCQHGMDDEEKETLMWKFDSRLAFVHSARELHPEFYKDC

Annotated regions: