Protein sequence:
MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKEVKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLSAEKRDKILRCLISDLNPSAVEKAVKKLQPNRNFIPLATSALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFFEVQAWVNPESKEEKTPEKSTALFSALWQPSKACEDYQDDDGRVLSKGLAEKVVKRITNQPAEVTEYKDVREKETAPLPYSLSALQIDAAKRFGMSAQAVLDTCQRLYETHRLITYPRSDCRYLPEEHFAERHNVLNAISTHCEAYQVLPNVILTEQRNRCWNDKKVEAHHAIIPTAKNRPVNLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQTAGWKELLGKEDDTENQEPLLPIVKKGQILHCERGEVMSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHSTETGRILIQALPNIATQPDMTAHWESQLTDISQKQATYQQFMHNLNQILPDLVRFVDLNALRQLSRIKMIKSDRAKPKSAVKKSSKSNGETD

Annotated regions:
phrase: LVNAGDPDREGQL
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LSVGRVQTPVLGLIVRRD
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: HRLITYPRS
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: IYSLIARQYLMQFCPD
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GLGTEATRAGIIEL
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKEVKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLSAEKRDKILRCLISDLNPSAVEKAVKK
type: DOMAIN
name: TOPRIM_TopoIII
description: DNA topoisomerase 3-like, TOPRIM domain

phrase: PLATSALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFFEVQAWVNPESKEEKTPEKSTALFSALWQPSKACEDYQDDDGRVLSKGLAEKVVKRITNQPAEVTEYKDVREKETAPLPYSLSALQIDAAKRFGMSAQAVLDTCQRLYETHRLITYPRSDCRYLPEEHFAERHNVLNAISTHCEAYQVLPNVILTEQRNRCWNDKKVEAHHAIIPTAKNRPVNLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQTAGWKELLGKEDDTENQEPLLPIVKKGQILHCERGEVMSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHSTETGRILIQALPNIATQPDMTAHWESQLTDISQKQATYQQF
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKEVKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLSAEKRDKILRCL
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: LFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKEVKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLSAEKRDKILR
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGDNDVVTWCVGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLLPRKEVKKQLSVVEKLIHQADTLVNAGDPDREGQLLVDEVFSYANLSA
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: KDVREKETAPLPYSLSALQIDAAKRFGMSAQAVLDTCQRLYETHRLITYPRSDCRYLPEEHFAERHNVLNAISTHCEAYQVLPNVILTEQRNRCWNDKKVEAHHAIIPTAKNRPVNLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQTAGWKELLGKEDDTENQEPLLPIVKKGQILHCERGEVMSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHSTETGRIL
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: KILRCLISDLNPSAVEKAVKKLQPNRNFIPLATSALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFF
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: IPLATSALARARADWLYGINMTRAYTIRGRQTGYDGVLSVGRVQTPVLGLIVRRDLEIEHFQPKDFFEVQAWVNPESKEEKTPEKSTALFSALWQPSKACEDYQDDDGRVLSKGLAEKVVKRITNQPAEVTEYKDVREKETAPLPYSLSALQIDAAKRFGMSAQAVLDTCQRLYETHRLITYPRSDCRYLPEEHFAERHNVLNAISTHCEAYQVLPNVILTEQRNRCWNDKKVEAHHAIIPTAKNRPVNLTQEERNIYSLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQTAGWKELLGKEDDTENQEPLLPIVKKGQILHCERGEVMSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLTKKGRNIHSTETGRILIQALPNIATQPDMTAHWESQLTDISQKQATYQQFMHNLNQILPDL
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: QRLYETHRLITYPRS
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site