nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
MQEVISYIQKAVLEISNALKFPDTSYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKAIISEEKDEILTLNERANFIVAYDPLDGSSLMDVNFAIGSIFAIYEEKANAKNLRAALYSMYGARLELVICKDQPKLYRLNANNEFIFIKDLKMNEKGKINATGGTQKFWEEKHAKFIKNLFDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGKTTNGKNRSLLELEFDKIHATTPCFFGSEYEISKLLKAYNE

Annotated regions:
phrase: NEKGKINATGGTQKFWEEKHAKFIKNLFDEGYRLRYSGAMVSDINQILLKGGGIFSYPATQDAPNGKLRAFFEVFPLAFIIEKAGGKTTNGKNRSLLELEFDKIHATTPCFFGSEYEISKLLKA
type: DOMAIN
name: FBPase_C_dom
description: Fructose-1-6-bisphosphatase class 1, C-terminal

phrase: TSYSQNQNFTGDTQLKFDVLSDEIITKTLSQCSSIKAIISEEKDEILTLNERANFIVAYDPLDGSSLMDVNFAIGSIFAIYEEKANAKNLRAALYSMYGARLELVICK
type: DOMAIN
name: FBPase_N
description: Fructose-1-6-bisphosphatase class I, N-terminal
Protein sequence:
MVSSQRPVPNKIQKQQYLSISPSNSVLKDDVELEFSDVFGPLPEEANDIAYDEPAVVYSRSHSLVGPCSLDSHSLKLTKLTLLETEDSIDLVECLEGESLKENDDFSGNDDSDNEKALEGDLVKVSGVVGIDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTDMSVLDSPASSPSSDPKANPFTNFTYVRPPPSFLHQSTTTL

Annotated regions:
phrase: FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKW
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: VSGRQCIANFDKCWTDMSVLDSPASSPSSDPKANPFTNFT
type: DOMAIN
name: Pkinase_C
description: Protein kinase, C-terminal

phrase: KGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTDMSVLDSPASSPSSDPKANPFTNFTYVRPPPSFLH
type: DOMAIN
name: AGC-kinase_C
description: AGC-kinase, C-terminal

phrase: KGINWKKLEAREVMPSFKPEVSGRQCIANFDKCWTDMSVLDSPASSPSSDPKANPFTNFTYV
type: DOMAIN
name: AGC-kinase_C
description: AGC-kinase, C-terminal

phrase: VGKGAFGKVYQVRKKETSEIYAM
type: BINDING_SITE
name: Protein_kinase_ATP_BS
description: Protein kinase, ATP binding site

phrase: FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKW
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: VGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKW
type: DOMAIN
name: STKc_AGC
description: Serine/Threonine Kinase AGC, catalytic domain

phrase: FEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKGKIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEPERRLGSGLSGAEEIKQHKW
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: IMHRDLKPENIL
type: ACTIVE_SITE
name: Ser/Thr_kinase_AS
description: Serine/threonine-protein kinase, active site
Protein sequence:
MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN

Annotated regions:
phrase: SADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRM
type: DOMAIN
name: Chemokine_IL8-like_dom
description: Chemokine interleukin-8-like domain

phrase: CCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFC
type: CONSERVED_SITE
name: Chemokine_CC_CS
description: CC chemokine, conserved site

phrase: DCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRM
type: DOMAIN
name: Chemokine_IL8-like_dom
description: Chemokine interleukin-8-like domain
Protein sequence:
MASSSSTQLPWSAWHARLHHKLLANPDLLPAKASLLIAVSGGQDSMALLGLLIDLQRKHGWSLEVWHGDHNWHKQSATIATELKNWCESHNLSFCSDQAKPGQTNNEATARHWRYEQLTLHAERLSSNNPNHPCRYVLTGHTSSDRAETLLLNLARGTDLAGLSSMRQCRPISKDHPHKNVQLIRPLLGFSREDTALICSELGLPIWLDPANSNPDFSRNRVRQEVLPVLESLHPGCSLRMAALAERLNHHHADQQAIAMLALNNLSKQNGLCRKDLAQLPITARTTLLAYWLKRSGAPSLPAVQLEQISQSIAPGKPPGSLHLAQGWKVQWQRNSVQLEHHD

Annotated regions:
phrase: SLLIAVSGGQDSMALLGLLIDLQRKHGWSLEVWHGDHNWHKQSATIATELKNWCESHNLSFCSDQAKPGQTNNEATARHWRYEQLTLHAERLSSNNPNHPCRYVLTGHTSSDRAETLLLNLARGTDLAGLSSMRQCRPISKDHPHKNVQLIRPLLGFSREDTALICSELGLPIWLDPANSNPDFSRNRVRQEVL
type: DOMAIN
name: tRNA_Ile_lys_synt_N
description: tRNA(Ile)-lysidine synthase, N-terminal

phrase: LLIAVSGGQDSMALLGLLIDLQRKHGWSLEVWHGDHNWHKQSATIATELKNWCESHNLSFCSDQAKPGQTNNEATARHWRYEQLTLHAERLSSNNPNHPCRYVLTGHTSSDRAETLLLNLARGTDLAGLSSMRQCRPISKDHPHKNVQLIRPLLGFSREDTALICSELGLPIWLDPANSNPDFSRNRVRQ
type: DOMAIN
name: TilS/TtcA_N
description: tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal

phrase: LCRKDLAQLPITARTTLLAYWLKRSGAPSLPAVQLEQISQSIAPGKPPGSLHLAQGWKVQWQRN
type: DOMAIN
name: tRNA_Ile_lys_synt_subst-bd
description: tRNA(Ile)-lysidine synthase, substrate-binding domain

phrase: LLIAVSGGQDSMALLGLLIDLQRKHGWSLEVWHGDHNWHKQSATIATELKNWCESHNLSFCSDQAKPGQTNNEATARHWRYEQLTLHAERLSSNNPNHPCRYVLTGHTSSDRAETLLLNLARGTDLAGLSSMRQCRPISKDHPHKNVQLIRPLLGFSREDTALICSELGLPIWLDPANSNPDFSRNRVRQEVL
type: DOMAIN
name: tRNA_Ile_lys_synt_N
description: tRNA(Ile)-lysidine synthase, N-terminal
Protein sequence:
MEIEHEKLQKKRVAIIGAGASGIPAAREALDHDWLPFVFESSTDIGGLWRYKPYETEEGTVMKTTVINTSKEMTAYSTFVPPSNFANFMHNRCMLEYLRLYADSFDFNKYLYLEHKVINVERCEGFENNGQWIVQYKKGNNSEVFHEIFDAAHSYKDQRGYDDQVVVVVGVGNSGVDIAVELSRVAKQVYLVTRRGTWVLFRNMDHSYPFDMALNTRWWHILKQIVPSSAVSWHLEKIFNRRFNHAKFGLKPKHSILAAHLTVNDELPNRLCCGTVRVKPNIREFLPDGNGIIFEDGSEIKNVDHLILATGYSFSFPLAEHGTLIPVVENEMDLYLYMYPPQLSPKNTLAVIGLIQPLGSIMPIAEMQARLFFEVLNGNVVLPKWRAMQDNIRERKEKLQARYVKSPRHTIQANKLNK

Annotated regions:
Protein sequence:
MRIGVLTGGGDSPGINAALRAIVRKAAAEGVEVIGFRDGWRGLVDDLTAPLGLKEVSGILPTGGTILGTSRTNPFKKENRDGKTVWERTDKVDKVLATYERHGLDCLIAIGGDDTLGVAAHLVPQGIKAIGIPQTIDNDLWGTDYSIGFPTALSIVMEALDRLHTTSHAHHRAMIVEVMGRDAGWIAVQGGMAGGADVILIPERPFSVEDVVARIRKRLDMDKRFSIIVVAEGAIPAELGYPVIRAEEREDNILRLELGHPPEMAKEKDAFGHPQYGGSIGYWLANRLQDYKKELEGLTPRVTVLAYLQRGGVATAFDRLLATRLGVRAVELALEGASGVMVGMQGEKVVPVPLEEVAANSPRLVPDELIELAEIFY

Annotated regions:
phrase: RIGVLTGGGDSPGINAALRAIVRKAAAEGVEVIGFRDGWRGLVDDLTAPLGLKEVSGILPTGGTILGTSRTNPFKKENRDGKTVWERTDKVDKVLATYERHGLDCLIAIGGDDTLGVAAHLVPQGIKAIGIPQTIDNDLWGTDYSIGFPTALSIVMEALDRLHTTSHAHHRAMIVEVMGRDAGWIAVQGGMAGGADVILIPERPFSVEDVVARIRKRLDMDKRFSIIVVAEGAIPAELGYPVIRAEEREDNILRLELGHPPEMAKEKDAFGHPQYGGSIGYWLANRLQDYKKELEGLTPRVTVLAYLQRGGVATAFDRLLATRLGVRAVE
type: DOMAIN
name: Phosphofructokinase_dom
description: Phosphofructokinase domain
Protein sequence:
MYMAIMIILFLSSILLSLLLLLRKHLSHFSYPNLPPGNTGLPLIGESFSFLSAGRQGHPEKFITDRVRRFSSSSSCVFKTHLFGSPTAVVTGASGNKFLFTNENKLVVSWWPDSVNKIFPSSMQTSSKEEARKLRMLLSQFMKPEALRRYVGVMDEIAQRHFETEWANQDQVIVFPLTKKFTFSIACRSFLSMEDPARVRQLEEQFNTVAVGIFSIPIDLPGTRFNRAIKASRLLRKEVSAIVRQRKEELKAGKALEEHDILSHMLMNIGETKDEDLADKIIGLLIGGHDTASIVCTFVVNYLAEFPHVYQRVLQEQKEILKEKKEKEGLRWEDIEKMRYSWNVACEVMRIVPPLSGTFREAIDHFSFKGFYIPKGWKLYWSATATHMNPDYFPEPERFEPNRFEGSGPKPYTYVPFGGGPRMCPGKEYARLEILIFMHNLVNRFKWEKVFPNENKIVVDPLPIPDKGLPIRIFPQS

Annotated regions:
phrase: FGGGPRMCP
type: CONSERVED_SITE
name: Cyt_P450_CS
description: Cytochrome P450, conserved site
Protein sequence:
MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIYFLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQAKLSDYIGAMMVVLFAPEDLQLVKGSPSLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQRNAYLKSVHQLDSDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKLSISYQASVSFEHQQEIYQQFMDQLKTTHQRDFLRKNTGVGPHRDDLIFYINGMNANFASQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNIRQTKLLEAVKKENVQTFITTTSLKHLSQLPKDISLFKVNKGTIALDSVMID

Annotated regions:
phrase: ILLLDDVMSELDNIRQTK
type: CONSERVED_SITE
name: DNA-binding_RecF_CS
description: DNA-binding, RecF, conserved site

phrase: FAPEDLQLVKGSPSLRRKFM
type: CONSERVED_SITE
name: DNA-binding_RecF_CS
description: DNA-binding, RecF, conserved site

phrase: IKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIYFLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQAKLSDYIGAMMVVLFAPEDLQLVKGSPSLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQRNAYLKSVHQLDSDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKLSISYQASVSFEHQQEIYQQFMDQLKTTHQRDFLRKNTGVGPHRDDLIFYINGMNANFASQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNIRQTKLLEAVKKENVQTFITTTSLKHLSQLPKDISLFKVNKG
type: DOMAIN
name: RecF/RecN/SMC_N
description: RecF/RecN/SMC, N-terminal
Protein sequence:
MAHVRTFTLPHYEAYPVHVALFKDVKNPSYLKSQLLEANPAFDYAFLDAAMVARLGIAWWSHAAANDRPQILSPTHLLSTTFITIHALCTHRQKTRTPHSELVFRLSPNNNIGESYKKFGISDTTTHLIAVKLPLKSSDAEAKEWLVDGEITNESVSQHLGSVVEGTSVEISEKGEELGQWCDIDKIRKVYKLGDGSAKKGKKGAAVNGDGAEKEGEKKQMEVVILGTIALKS

Annotated regions:
Protein sequence:
MESPSVNTQKFILKLFPEIMVKGSSAKRQMIGQLYNNLIKLLNTYSPEIKVRKFSDKIEVVSPTNVLTEVRQTLLHTPGIEQVLEALQFDNMDELSDIKVKVSEIMAKTVEGKTFVVRAKRTGTHPFNSTVLEQTVGGYMLAHCNAKGVDLHHPEVTVRIELINKQLNIITTKYAGLGGFPIGTQGDILSLMSGGFDSTVASYLTMKRGIKTHFIFFNLGGIAHEIGVKQVALYLWSKYGASHRVSFISVPFDKVIEEIFRSTHETYMGVTLKRLMLMAAEKIANTMEIDALVTGESVAQVSSQTLRNLALIDQVTNKLVLRPLATMNKPDIINIANEIGTRRFAENMPEYCGVISKNPITHGSYKRMEKEAKRFDYAVLDKAAEEAVMIYVDEIIDDVSNAAPIEVIHDLSKGEYVVIDIRPEEECLSTSCKSIKIPFHKLKTEFKKLPQDKEYLLYCEKGIMSQLHAQYLRDSESCENVRVYRPQ

Annotated regions:
phrase: LSDIKVKVSEIMAKTVEGKTFVVRAKRTGTHPFNSTVLEQTVGGYMLAHCNAKGVDLHHPEVTVRIELINKQLN
type: DOMAIN
name: THUMP_dom
description: THUMP domain

phrase: TEVRQTLLHTPGIEQVLEALQFDNMDELSDIKVKVSEIMAKTVEGKTFVVRAKRTGTHPFNSTVLEQTVGGYMLAHCNAKGVDLHHPEVTVRIELINKQLNIITT
type: DOMAIN
name: THUMP_dom
description: THUMP domain

phrase: SKGEYVVIDIRPEEECLSTSCKSIKIPFHKLKTEFKKLPQDKEYLLYCEKGIMSQLHAQYLRDSESCENVRV
type: DOMAIN
name: Rhodanese-like_dom
description: Rhodanese-like domain

phrase: KFILKLFPEIMVKGSSAKRQMIGQLYNNLIKLLNTYSPEIKVRKFSDKIEVVSPTNVLTEVRQTLLHTPGIEQVLEALQFDNMDELSDIKVKVSEIMAKTVEGKTFVVRAKRTGTHPFNSTVLEQTVGGYMLAHCNAKGVDLHHPEVTVRIELINKQLNIITTKYAGL
type: DOMAIN
name: THUMP_ThiI
description: ThiI, THUMP domain

phrase: ILKLFPEIMVKGSSAKRQMIGQLYNNLIKLLNTYSPEIKVRKFSDKIEVVSPTNVLTEVRQTLLHTPGIEQVLEALQFDNMDELSDIKVKVSEIMAKTVEGKTFVVRAKRTGTHPFNSTVLEQTVGGYMLAHCNAKGVDLHHPEVTVRIELINKQLNIITTKYAGLGGFPIGTQGDILSLMSGGFDSTVASYLTMKRGIKTHFIFFNLGGIAHEIGVKQVALYLWSKYGASHRVSFISVPFDKVIEEIFRSTHETYMGVTLKRLMLMAAEKIANTMEIDALVTGESVAQVSSQTLRNLALIDQVTNKLVLRPLATMNKPDIINIANEIGTRRFAENMPEYCGVISKNPITHGSYKRMEKEAKRFD
type: DOMAIN
name: ThiI_N
description: ThiI, N-terminal

phrase: QVLEALQFDNMDELSDIKVKVSEIMAKTVEGKTFVVRAKRTGTHPFNSTVLEQTVGGYMLAHCNAKGVDLHHPEVTVRIELINKQLNIITT
type: DOMAIN
name: THUMP_dom
description: THUMP domain

phrase: YVDEIIDDVSNAAPIEVIHDLSKGEYVVIDIRPEEECLSTSCKSIKIPFHKLKTEFKKLPQDKEYLLYCEKGIMSQLHAQYLRDSESCENVRVYR
type: DOMAIN
name: THII_Thiazole_biosynth_dom
description: ThiI, thiazole biosynthesis domain

phrase: GTQGDILSLMSGGFDSTVASYLTMKRGIKTHFIFFNLGGIAHEIGVKQVALYLWSKYGASHRVSFISVPFDKVIEEIFRSTHETYMGVTLKRLMLMAAEKIANTMEIDALVTGESVAQVSSQTLRNLALIDQVTNKLVLRPLATMNKPDIINIANEIGTRRFAENMPEYCGVISKNPITHGSYKRMEKEAKR
type: DOMAIN
name: ThiI_AANH
description: Thil, AANH domain

phrase: VIHDLSKGEYVVIDIRPEEECLSTSCKSIKIPFHKLKTEFKKLPQDKEYLLYCEKGIMSQLHAQYLRDSESCENVRV
type: DOMAIN
name: Rhodanese-like_dom
description: Rhodanese-like domain
Protein sequence:
MSKQPQQSLTLRSPAKLNLFLHIVGQRPDGYHLLQSVFQLIDWTDTVHLKRIPENEVRRINPIPDVSPEQDLVVRAAKLVKDFCKIDLGVEIDLKKEIPMGAGLGGGSSDAASTLIGLNTLWNLDLDKKTLSNLGLKLGADVPFFIFGQNAFVEGIGEQIQEISLENRDFLVIFPNRAIPTVSIFHDPELTRDHAPITIDGFLASPLSNQINDCQAVAMRICPEVKQALDWVSQALPGSAPRMSGSGSSVFAVLDPKTDSVKLENLLQSLPKGWIGRVVRGLNKNPAYNLISSD

Annotated regions:
phrase: LVVRAAKLVKDFCKIDLGVEIDLKKEIPMGAGLGGGSSDAASTLIGLNTLWNLDLDKKTLSNLGLKLGADVPFFIFG
type: DOMAIN
name: GHMP_kinase_N_dom
description: GHMP kinase N-terminal domain

phrase: QINDCQAVAMRICPEVKQALDWVSQALPGSAPRMSGSGSSVFAVLDPKTDSV
type: DOMAIN
name: GHMP_kinase_C_dom
description: GHMP kinase, C-terminal domain
Protein sequence:
MSAQNPLFSGSIVALVTPMNHYGEVDFSCLEKLVEHHIEAGSNALVSVGTTGESATLSIEENVKVIEKTVEFAKGRIPIIAGAGANATSEAITMTKLLRDSGVAGCLSVVPYYNKPTQEGIYQHFKAIAECTNLPQILYNVPSRTGSDMKPETVARLAKIENIVGIKEATGDVSRIVKIKQLAGKNFIVLSGDDATGLEAIKLGAEGVISVTNNIAAKDMADMYRYALVGDFDKAEEINARLMRLHHDLFIESNPIPVKWAAYRLGLIKSSHLRLPLTTLSEEIQPKVEDALKIAGLL

Annotated regions:
phrase: YNVPSRTGSDMKPETVARLAKIENIVGIKE
type: ACTIVE_SITE
name: Schiff_base-form_aldolases_AS
description: Schiff base-forming aldolase, active site

phrase: ALVSVGTTGESATLSIE
type: CONSERVED_SITE
name: Schiff_base-form_aldolases_CS
description: Schiff base-forming aldolase, conserved site
Protein sequence:
MPISQTYLGSAKAPAGIKSFYFIRHGATDLNEKEIVVNGEKLWGVQGSGTNIGLNAKGERQALLAGNVLRSLPISGVVCSPLLRALQTAFIANPGCPSFQIANDLQERDFGTHEGGFGPLQMFEDDYPDCESTEIFSIHVAKALKHACRENVLLVAHGGVLRVVAALLGVAITDEHTANGRVLHFSVVADNWSVRVIQSPVVMVSGVTRGIGKAIAEDLIRHGYRVSLGARNIQDLVAAFGDENEALHYARFDALDHSSMKDWVDTTIAKFNRIDGLVNNAGCGDHVDLEKEINVELLQKQWDINCVAPLIMTKLCMPYLIESGSGRIVNLNSMSGQRVANSLVGYNMTKHGLAGLTKTTQHVGWDHGVRAVDICPGFVATNMSSWTNLIGPDEMIQPEDIAKLVRAAMERPNRAFVPKNEVLCMKESTR

Annotated regions:
phrase: SMSGQRVANSLVGYNMTKHGLAGLTKTT
type: CONSERVED_SITE
name: Sc_DH/Rdtase_CS
description: Short-chain dehydrogenase/reductase, conserved site
Protein sequence:
MIISASTDYRAAAQRRLPPFLFHYIDGGAYGEHTLRRNTADLADIALRQRILKNMSDLSLETQLFGEKLAMPVVLAPVGLTGMYARRGEVQAARAAAQKGIPFTLSTVSVCPIEEVAPAIDRPMWFQLYVLKDRGFMRSALERAQAAGVKTLVFTVDMPTPGARYRDAHSGMSGPNAAARRMLQAVTHPQWAWDVGLNGKPHDLGNVSAYRGKPTTLEDYIGWLAANFDPSISWQDLAWIREFWKGPMIIKGILDPEDAKEAVRFGADGIVVSNHGGRQLDGVLSTAHALPAIADAVKGDITILADSGIRSGLDVVRMIALGADGVMLGRAFVYALAAAGEAGVVNLLNLIEKEMRVAMTLTGAKSIADITSDSLVQVTQRRLDGL

Annotated regions:
phrase: MIISASTDYRAAAQRRLPPFLFHYIDGGAYGEHTLRRNTADLADIALRQRILKNMSDLSLETQLFGEKLAMPVVLAPVGLTGMYARRGEVQAARAAAQKGIPFTLSTVSVCPIEEVAPAIDRPMWFQLYVLKDRGFMRSALERAQAAGVKTLVFTVDMPTPGARYRDAHSGMSGPNAAARRMLQAVTHPQWAWDVGLNGKPHDLGNVSAYRGKPTTLEDYIGWLAANFDPSISWQDLAWIREFWKGPMIIKGILDPEDAKEAVRFGADGIVVSNHGGRQLDGVLSTAHALPAIADAVKGDITILADSGIRSGLDVVRMIALGADGVMLGRAFVYALAAAGEAGVVNLLNLIEKEMRVAMTLTGAKSIADITSDSLVQVT
type: DOMAIN
name: FMN_HAD
description: FMN hydroxy acid dehydrogenase domain

phrase: SNHGGR
type: ACTIVE_SITE
name: FMN_hydac_DH_AS
description: FMN-dependent alpha-hydroxy acid dehydrogenase, active site

phrase: AQRRLPPFLFHYIDGGAYGEHTLRRNTADLADIALRQRILKNMSDLSLETQLFGEKLAMPVVLAPVGLTGMYARRGEVQAARAAAQKGIPFTLSTVSVCPIEEVAPAIDRPMWFQLYVLKDRGFMRSALERAQAAGVKTLVFTVDMPTPGARYRDAHSGMSGPNAAARRMLQAVTHPQWAWDVGLNGKPHDLGNVSAYRGKPTTLEDYIGWLAANFDPSISWQDLAWIREFWKGPMIIKGILDPEDAKEAVRFGADGIVVSNHGGRQLDGVLSTAHALPAIADAVKGDITILADSGIRSGLDVVRMIALGADGVMLGRAFVYALAAAGEAGVVNLLNLIEKEMRVAMTLTGAKSIADITSDS
type: DOMAIN
name: FMN-dep_DH
description: FMN-dependent dehydrogenase
Protein sequence:
MGHMVNAVKQIPTFLDLGANALEMDVTFKNEEPTYTYHGVPCDAFRDCIRWEYFNVFAKTLREYTTPGFDKYREQLILLVFDLKTGDMNNAQARTAGVNTAKQLLQYYWNNDNNGGRAYVVLSIPDIAQHELIKGFKETLKKEGHENLLDKVGYDFSGPYLPRLPTLDETHEAFKKAGVEGHVWLSDGLTNFSPLGDMARLKEAIKSRDSANGFINKIYYWSVDKVSTAEKALKVGVDGIVTNHPDVIIGVLNENGFKDKYRLATYDDDPWETFGK

Annotated regions:
Protein sequence:
MEKTLSGILEGVQATVIGNGDEPVSGIAYRSDEVHPGDAFFCIVGTVSDGHSYAQDAIDHGAKSLVVERKVYLADATEVTEAVASDTRKAMAQASVNFYDDPSADFSLVGITGTNGKTTTTYLVQSIVEHAGKRCGVIGTVGVRIGGVREKAERTTPESPDLQRLFARMRDASEDVVAMEVSSHALDLDRTWGSHFAVTAFTNLTQDHLDYHHTFEAYFEAKARLFSSDYPAKRVICIDDAWGGRLLERCSAAGDAIVTTGFNEAAQIHPVSVDYHDTHTSIVLDVRGQQVAFDYPLVGRFNVENVMTAFGVGLSLGIPAAIIAQALREAPQVPGRLQRVPSPAGCDVSVFVDYAHTPDALAKALSSVKEFARERTLVVFGCGGDRDATKRPLMGQAALAADLVYVTSDNPRSEDPRAIIDDITAGMAAGAGRFEVQPDRGRAIREALAAARPGDAVLIAGKGHEDYQIIGSKTIHFDDCECAAAALAELFGPDAAKDRP

Annotated regions:
phrase: VGITGTNGKTTTTYLVQSIVEHAG
type: CONSERVED_SITE
name: Folylpolyglutamate_synth_CS
description: Folylpolyglutamate synthetase, conserved site

phrase: ITGTNGKTTTTYLVQSIVEHAGKRCGVIGTVGVRIGGVREKAERTTPESPDLQRLFARMRDASEDVVAMEVSSHALDLDRTWGSHFAVTAFTNLTQDHLDYHHTFEAYFEAKARLFSSDYPAKRVICIDDAWGGRLLERCSAAGDAIVTTGFNEAAQIHPVSVDYHDTHTSIVLDVRGQQVAFDYPLVGRFNVENVMTAFG
type: DOMAIN
name: Mur_ligase_cen
description: Mur ligase, central

phrase: VSGIAYRSDEVHPGDAFFCIVGTVSDGHSYAQDAIDHGAKSLVVERKVYLADATEVTEAVASDTRKAMAQASVNFY
type: DOMAIN
name: Mur_ligase_N
description: Mur ligase, N-terminal catalytic domain

phrase: GRLQRVPSPAGCDVSVFVDYAHTPDALAKALSSVKEFARERTLVVFGCGGDRDATKRPLMGQAALAADLVYVTSDNPRSEDPRAIIDDITAGMAAGAGRFEVQPDRGRAIREALAAARPGDAVLIAGK
type: DOMAIN
name: Mur_ligase_C
description: Mur ligase, C-terminal
Protein sequence:
MSITKEFDTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMTIAVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPADLIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLFSQFCLGK

Annotated regions:
phrase: TAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLN
type: DOMAIN
name: GTP-bd
description: GTP binding domain

phrase: TITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEILQLLIRQGARMAEPGEFTKRAFLNG
type: DOMAIN
name: GTP-bd_TrmE_N
description: GTP-binding protein TrmE, N-terminal

phrase: AIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPADLIPISVLTNQNI
type: DOMAIN
name: Small_GTP-bd
description: Small GTP-binding domain

phrase: REGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPADLIPISVLTNQNINLIEDRINQL
type: DOMAIN
name: G_TrmE
description: TrmE-type guanine nucleotide-binding domain

phrase: LTQAEAVMDIIRAKTDKAMTIAVKQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLREKTQEFQSLLENLLRTAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPADLIPISVLTNQNINLIEDRINQLFFDNAGLVEQDATYLSNARHISLIEKAVQSLEAVNDGLALGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLFSQF
type: DOMAIN
name: MnmE_helical
description: MnmE, helical domain

phrase: GLSTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNIKGVPLKLVDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTDQDRALLNLSQDSNRIILLNKTDLEQKIELEQLPADLIPISVLTNQNINLIEDRINQLF
type: DOMAIN
name: G_TrmE
description: TrmE-type guanine nucleotide-binding domain

phrase: DTITAISTPLGEGAIGIVRLSGTDALAIAQSVFKGKNLEQVASHTINYGHIIDPKTGTIIDEVMVSVMLAPKTFTRENVVEINTHGGIAVTNEILQLLIRQGARMAEPGEFTKRAFLN
type: DOMAIN
name: GTP-bd_TrmE_N
description: GTP-binding protein TrmE, N-terminal
Protein sequence:
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKTIEQVREYANQILGMQLVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRVSQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARTILQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK

Annotated regions:
phrase: KIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKTIEQVREYANQILGMQLVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRVSQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARTILQGLYKAFWETDASLAEINPL
type: DOMAIN
name: ATP-grasp_succ-CoA_synth-type
description: ATP-grasp fold, succinyl-CoA synthetase-type

phrase: LVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKV
type: DOMAIN
name: SUCC_ACL_C
description: ATP-citrate synthase/succinyl-CoA ligase, C-terminal domain

phrase: GNIGCLVNGAGLAMATMDTIKLFGG
type: CONSERVED_SITE
name: Succ-CoA_synthase_bsu_CS
description: Succinyl-CoA synthetase, beta subunit, conserved site

phrase: KEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKTIEQVREYANQILGMQLVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRVSQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARTILQGLYKAFWETDASLAEINPLNVSGDGKVTALDAKFNFDSNALFRHPEIV
type: DOMAIN
name: ATP-grasp
description: ATP-grasp fold
Protein sequence:
MVSCQGTRPCIVNLLTMPSEDKLGEEISTRVINEYSKLKSACRPIIRPSGIREWTILAGVAAINRDGGANKIEILSIATGVKALPDSELQRSEGKILHDCHAEILALRGANTVLLNRIQNYNPSSGDKFIQHNDEIPARFNLKENWELALYISRLPCGDASMSFLNDNCKNDDFIKIEDSDEFQYVDRSVKTILRGRLNFNRRNVVRTKPGRYDSNITLSKSCSDKLLMKQRSSVLNCLNYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPNLDNEIKFLNCLKPFYDDKLDEEDVPGLMCSVKLFMDDFSTEEAILNGVRNGFYTKSSKPLRKHCQSQVSRFAQWELFKKIRPEYEGISYLEFKSRQKKRSQLIIAIKNILSPDGWIPTRTDDVK

Annotated regions:
phrase: SIATGVKALPDSELQRSEGKILHDCHAEILALRGANTVLLNRIQNYNPSSGDKFIQHNDEIPARFNLKENWELALYISRLPCGDASMSFLNDNCKNDDFIKIEDSDEFQYVDRSVKTILRGRLNFNRRNVVRTKPGRYDSNITLSKSCSDKLLMKQRSSVLNCLNYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPNLDNEIKFLNCLKPF
type: DOMAIN
name: A_deamin
description: Adenosine deaminase/editase

phrase: SIATGVKALPDSELQRSEGKILHDCHAEILALRGANTVLLNRIQNYNPSSGDKFIQHNDEIPARFNLKENWELALYISRLPCGDASMSFLNDNCKNDDFIKIEDSDEFQYVDRSVKTILRGRLNFNRRNVVRTKPGRYDSNITLSKSCSDKLLMKQRSSVLNCLNYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPNLDNEIKFLNCLKPFYDDKLDEEDVPGLMCSVKLFMDDFSTEEAILNGVRNGFYTKSSKPLRKHCQSQVSRFAQWELFKKI
type: DOMAIN
name: A_deamin
description: Adenosine deaminase/editase

phrase: KLGEEISTRVINEYSKLKSACRPIIRPSGIREWTILAGVAAINRDGGANKIEILSIATGVKALPDSELQRSEGKILHDCHAEILALRGANTVLLNRIQNYNPSSGDKFIQHNDEIPARFNLKENWELALYISRLPCGDASMSFLNDNCKNDDFIKIEDSDEFQYVDRSVKTILRGRLNFNRRNVVRTKPGRYDSNITLSKSCSDKLLMKQRSSVLNCLNYELFEKPVFLKYIVIPNLEDETKHHLEQSFHTRLPNLDNEIKFLNCLKPFYDDKLDEEDVPGLMCSVKLFMDDFSTEEAILNGVRNGFYTKSSKPLRKHCQSQVSRFAQWELFKKIRPEYEGISYLEFKSRQKKRSQLIIAIKNILSPDGWIPTRTDDV
type: DOMAIN
name: A_deamin
description: Adenosine deaminase/editase
Protein sequence:
MMWPPSLLLLLLLLRRGAQGKPSPDAGPHGQGRVHHAAPLSEAPHDDAHGNFQYDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRSWIAHTQQRHIRDSVSAAWNTYDTDRDGRVGWEELRNATYGHYEPGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYTAEPGEEEPAWVQTEREQFRDFRDLNKDGKLNGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDEL

Annotated regions:
phrase: DLNKDGKLNGSE
type: BINDING_SITE
name: EF_Hand_1_Ca_BS
description: EF-Hand 1, calcium-binding site

phrase: KMLARDERRFRVADQDGDSMATREELTAFLHPEEF
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: EANHLLHESDTDKDGRLSKAEILGNWNM
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: SVSAAWNTYDTDRDGRVGWEELRNATYG
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: VIAETLEDLDRNKDGYVQVEEYIADLYT
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: YDTDRDGRVGWEELR
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: MRDIVIAETLEDLDRNKDGYVQVEEYIADLYTAEP
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: ERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYI
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: DTDRDGRVGWEE
type: BINDING_SITE
name: EF_Hand_1_Ca_BS
description: EF-Hand 1, calcium-binding site

phrase: HIRDSVSAAWNTYDTDRDGRVGWEELRNATYGHYE
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain

phrase: DTDKDGRLSKAE
type: BINDING_SITE
name: EF_Hand_1_Ca_BS
description: EF-Hand 1, calcium-binding site

phrase: DRNKDGYVQVEE
type: BINDING_SITE
name: EF_Hand_1_Ca_BS
description: EF-Hand 1, calcium-binding site
Protein sequence:
MDSLSLPTVCDVVVPALNVDNLIRDYVSNVRADDSNNVSRFLGEVALKEIKSQVDTSNGDFQKLNVGFRLTPDEKNALKANFPGLEIAFRDSCHSSHSFAAAHRVCETLNIYNRFKTKTERIIDLGGNYVTHAKQGRSNVHSCCPILDVRDGARHTDRYISLAASVENRHRELPVDFCCHKFEECDVKAPFAMAIHSISDIPISTVATHCVRRGVRKLIASVMMDPLMMLYDKGHIPLLNVDWEKEDVEETGKTLIHFHFVDAPGLSYSHDFDTLSQYMITNQVIVNNSYSFRVERTACLSGVYIVEMTLSMTDGHSLAYLKPMRDVSCAWLSSLRKKVFVKLAVPISAEWYTEQFEVRHALMDESLVRYVSEAAFRQFSKTKDPETLVQYIATMLSSSSNHVVINGITMRSGSPIKFDEYVPLAVTFYVMAAWRYKMIAPGIDAVKTRTEKNVDILDEKGLIKEDFNVVNALLEDAGLIEPKLPHFTDVIKNAGLRGFGKKTIEKTRDDVLLIKPRSLLREVIYTVRSVFGLTILDSDYNLVSGVPSHMKATHVWSVFVGNLAFPSCLNVNECVNELLVNHMEMMEETKKEETRQQAFKDARDRALMTIAKAIEKDQTIKDGLLPILDLCKIKEELTAASNSLSLTPEAIEQTDSRLMKASGSDVNPYADSIKEAIHYFNEVEVANTRNLRSLGIYLGWSIPKNKQTYDALQGRNESVRVYVPYENKWYPSAPTSQYERAMTVDGYFSLPMEFEAITDGCRREISKY

Annotated regions:
phrase: AFRDSCHSSHSFAAAHRVCETLNIYNRFKTKTERIIDLGGNYVTHAKQGRSNVHSCCPILDVRDGARHTDRYISLAASVENRHRELPVDFCCHKFEECDVKAPFAMAIHSISDIPISTVATHCVRRGVRKLIASVMMDPLMMLYDKGHIPLLNVDWEKEDVEETGKTLIHFHFVDAPGLSYSHDFDTLSQY
type: DOMAIN
name: Alphavirus-like_MT_dom
description: Alphavirus-like methyltransferase domain

phrase: FRLTPDEKNALKANFPGLEIAFRDSCHSSHSFAAAHRVCETLNIYNRFKTKTERIIDLGGNYVTHAKQGRSNVHSCCPILDVRDGARHTDRYISLAASVENRHRELPVDFCCHKFEECDVKAPFAMAIHSISDIPISTVATHCVRRGVRKLIASVMMDPLMMLYDKGHIPLLNVDWEKEDVEETGKTLIHFHFVDAPGLSYSHDFDTLSQYMITNQVIVNNSYSFRVERTACLSGVYIVEMTLSMTDGHSLAYLKPMRDVSCAWLSSLRKKVFVKLAVPISAEWYTEQFEVRHALMDESLVRYVSEAAFRQFSKTKDPETLVQYIATMLSSSSNHVVINGITMRSGSPIKFDE
type: DOMAIN
name: Alphavirus-like_MT_dom
description: Alphavirus-like methyltransferase domain