nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
MPNIIWIPFRETQAVDLITGLGDTIEKQLNQPRDKFTADLKTANDLRNNILNPQPNASYLDHLTKYYAQLTYWTTKFPAGCDSLEFMWYGTLAYTANAAPVISQSLHFERCNLLYNLGSLYSQMGVNEGRQDADGLKMSFNYFQMAAGCFQILIENGLPDLESLNMRGLEYDTICCVRDLMLAQAQECFWQRSLLSGSRNSLVAKLAQQVSLLYDSALAWAQKSPQVRSEWVHHMTCKRQHFLAVAHYRMARDALDGCRYGEEIARLKAALNAIKEGTGKGMLRRYLVESVADDLNGIIDVVTEDLKRAEKDNNLIYLQSVPQTTALAPITPALMVKCTPPVELAKPIEFLTKDKLGLPLFVKLTPFAFHQALVLYSQECDKIVSSIESQLKNCTNSKNQALVEMALPGSLDSVEKPKGIPADIIAHSDQIKSERGLETTREAVKDVQRLAATARQELEAAKAVLDDERSEDEMLRRKNNSGWTRFDSKEAGAHLYTRLAELEQYLADAGASDKLVRGKLDEIDYLLSILNSGRSALENYLPSSVSGVRSPEVKRQVPHLRDLLNNLESLEIKRAQYMDRLSLKQQNDDIEPVLEYHMNKLIREKHANLRLTLADFEPITSKELEKYTVDQDWASEQKELQEEVLEKLDVANKDFRSSLDMNDAAIHRENAIQSLEVAYFSYQEQKDHLDAGRNFYNQLLGEISIFHKNCKQFVYERKMEGASLEHELSSMHLSEHEHSGGHSDTSSTPLAAPRAQRASNLSMWSPEDGIRFG

Annotated regions:
phrase: GIPADIIAHSDQIKSERGLETTREAVKDVQRLAATARQELEAAKAVLDDERSEDEMLRRKNNSGWTRFDSKEAGAHLYTRLAELEQYLADAGASDKLVRGKLDEIDYLLSILNSGRSALENYLPSSVSGVRSPEVKRQVPHLRDLLNNLESLEIKRAQYMDRLSLKQQNDDIEPVLEYHMNKLIREKHANLRLTLADFEPITSKELEKYTVDQDWASEQKELQEEVLEKLDVANKDFRSSLDMNDAAIHRENAIQSLEVAYFSYQEQKDHLDAGRNFYNQLLGEISIFHKNCKQFVYERKM
type: DOMAIN
name: ALIX_V_dom
description: ALIX V-shaped domain

phrase: NIIWIPFRETQAVDLITGLGDTIEKQLNQPRDKFTADLKTANDLRNNILNPQPNASYLDHLTKYYAQLTYWTTKFPAGCDSLEFMWYGTLAYTANAAPVISQSLHFERCNLLYNLGSLYSQMGVNEGRQDADGLKMSFNYFQMAAGCFQILIENGLPDLESLNMRGLEYDTICCVRDLMLAQAQECFWQRSLLSGSRNSLVAKLAQQVSLLYDSALAWAQKSPQVRSEWVHHMTCKRQHFLAVAHYRMARDALDGCRYGEEIARLKAALNAIKEGTGKGMLRRYLVESVADDLNGIIDVVTEDLKRAEKDNNLIYLQSVPQTTALAPITPALMVKCTPPVELAKPIEFLTKDKLGLPLFVKLTPFAFHQALVLYSQECDKIVSSIESQLKNCTNS
type: DOMAIN
name: BRO1_dom
description: BRO1 domain

phrase: NIIWIPFRETQAVDLITGLGDTIEKQLNQPRDKFTADLKTANDLRNNILNPQPNASYLDHLTKYYAQLTYWTTKFPAGCDSLEFMWYGTLAYTANAAPVISQSLHFERCNLLYNLGSLYSQMGVNEGRQDADGLKMSFNYFQMAAGCFQILIENGLPDLESLNMRGLEYDTICCVRDLMLAQAQECFWQRSLLSGSRNSLVAKLAQQVSLLYDSALAWAQKSPQVRSEWVHHMTCKRQHFLAVAHYRMARDALDGCRYGEEIARLKAALNAIKEGTGKGMLRRYLVESVADDLNGIIDVVTEDLKRAEKDNNLIYLQSVPQTTALAPITPALMVKCTPPVELAKPIEFLTKDKLGLPLFVKLTPFAFHQALVLYSQECDKIVSSI
type: DOMAIN
name: BRO1_dom
description: BRO1 domain

phrase: IIWIPFRETQAVDLITGLGDTIEKQLNQPRDKFTADLKTANDLRNNILNPQPNASYLDHLTKYYAQLTYWTTKFPAGCDSLEFMWYGTLAYTANAAPVISQSLHFERCNLLYNLGSLYSQMGVNEGRQDADGLKMSFNYFQMAAGCFQILIENGLPDLESLNMRGLEYDTICCVRDLMLAQAQECFWQRSLLSGSRNSLVAKLAQQVSLLYDSALAWAQKSPQVRSEWVHHMTCKRQHFLAVAHYRMARDALDGCRYGEEIARLKAALNAIKEGTGKGMLRRYLVESVADDLNGIIDVVTEDLKRAEKDNNLIYLQSVPQTTALAPITPALMVKCTPPVELAKPIEFLTKDKLGLPLFVKLTPFAFHQALVLYSQECDKI
type: DOMAIN
name: BRO1_dom
description: BRO1 domain
Protein sequence:
MDLLKFSSLAISEINFLHESSFDSIDHSWFLLIGCKLDQDDEIYIPINGNEAESQWYIEKVIRIPMQENDKINQERLERRINLTKVTQKDICILGILDLCQLEEDENITNKVTEKVLTQLTALALKYLIKYNVFRQHTSFQEAVNSLKGYKIENSVQIGAEIILDFLQDKVQIKDVNDRYQIPTPNNTVDPGFDEFQLIDMKDKEINIQKYNNNTIRKLLEKINRMIIFLKNYDATDKPFSSTQDVILRKISMLVTQLQRGGTSDMNYLLDNKINEIKLLEISCKQWEISNMLKK

Annotated regions:
Protein sequence:
MTAPVWLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAEYAAVAQELSVVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAAGEHEAAAAGYVCALAEMPTLPELAANHLTHAVLVATNFFGINTIPIALNEADYVRMWVQAATVMSAYEAVVGAALVATPHTGPAPVIVKPGANEASNAVAAATITPFPFGELAKFLEMAAQAFTEVGELIMKSAEAWAVGFVELITGLVNFEPWLVLTGMIDMFFATVGFALGVFVLVPLLEFAVVLELAILSIGWIISNIFGAIPVLGGPLLGALAAAVVPGVAGLAGVAGLAALPAVGAAAGAPAALVGSVAPVSGGVVSPQARLVSAVEPAPASTSVSVLASDRGAGALGFVGTAGKESVGQPAGLTVLADEFGDGAPVPMLPGSWGPDLVGVAGDGGLVSV

Annotated regions:
phrase: WLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAEYAAVAQELSVVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAAGEHEAAAAGYVCALAEMPTLPELAANHLTHAVLVATNFFGINTIPIALNEADYVRMWVQAATVMSAYEAVVGAALVA
type: DOMAIN
name: PPE_dom
description: PPE domain

phrase: ASDRGAGALGFVGTAGKESVGQPAGLTVLADEFGDGAPVPMLPGS
type: DOMAIN
name: PPE-PPW_C
description: PPE-PPW subfamily, C-terminal
Protein sequence:
MTSAQRKDDHVRLAIEQHNAHSGRNQFDDVSFVHHALAGIDRPDVSLATSFAGISWQVPIYINAMTGGSEKTGLINRDLATAARETGVPIASGSMNAYIKDPSCADTFRVLRDENPNGFVIANINATTTVDNAQRAIDLIEANALQIHINTAQETPMPEGDRSFASWVPQIEKIAAAVDIPVIVKEVGNGLSRQTILLLADLGVQAADVSGRGGTDFARIENGRRELGDYAFLHGWGQSTAACLLDAQDISLPVLASGGVRHPLDVVRALALGARAVGSSAGFLRTLMDDGVDALITKLTTWLDQLAALQTMLGARTPADLTRCDVLLHGELRDFCADRGIDTRRLAQRSSSIEALQTTGSTR

Annotated regions:
phrase: FASWVPQIEKIAAAVDIPVIVKEVGNGLSRQTILLLADLGVQAADVSGRGGTDFARIENGRRELGDYAFLHGWGQSTAACLLDAQDISLPVLASGGVRHPLDVVRALALGARAVGSSAGFLRTLMDDGVDALITKLTTWLDQLAALQTMLGARTPADLT
type: DOMAIN
name: FMN-dep_DH
description: FMN-dependent dehydrogenase
Protein sequence:
MSEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAAAVKKFGRIASEGLTAIKINGLTSVVIEVNSETDFVARNEQFQNLVKDIVNLAIIAQNIDALKISKMQSGKSVEEEIIENIATIGENLTLRRMDILEISNGAIGSYVHNEVVPHLGKISVLVGLESNAKDKAKLAALAKQIAVHVAGNNPQSIDTLSLDQALVERERKVFFEKSKEEGKPDHIIEKMVEGRIRKFFSEVVLLQQNFLFEPKLTVAEVIKNAEQELGAEIKITKFIRYALGEGIEHEEKNFADEVASITKC

Annotated regions:
phrase: VVIEVNSETDFVARNEQFQNLVKDIVNLAIIAQNIDALKISKMQSGKSVEEEIIENIATIGENLTLRRMDILEISNGAIGSYVHNEVVPHLGKISVLVGLESNAKDKAKLAALAKQIAVHVAGNNPQSIDTLSLDQALVERERKVFFEKSKEEGKPDHIIEKMVEGRIRKFFSEVVLLQQNFLFEPKLTVAEVIKNAEQELGAEIKITKFIRYALG
type: DOMAIN
name: Transl_elong_EFTs/EF1B_dimer
description: Translation elongation factor EFTs/EF1B, dimerisation

phrase: LREKTGAGMMDCKKA
type: CONSERVED_SITE
name: Transl_elong_Ts_CS
description: Translation elongation factor Ts, conserved site

phrase: EVNSETDFVA
type: CONSERVED_SITE
name: Transl_elong_Ts_CS
description: Translation elongation factor Ts, conserved site
Protein sequence:
MVQSYEDMLKAAYSGIGEPTETGERFVMPKAKIYIEGKTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDGNRAVFNGKFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGSKRPIRKRKAKTEVQGPAIEEGKELEVHIESISKKGDGVARIGKYILYVAGTKAGQNVKVRITRISGQVAFTQKIL

Annotated regions:
phrase: GERFVMPKAKIYIEGKTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDGNRAVFNGKFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGS
type: DOMAIN
name: Transl_init_fac_IF2/IF5_dom
description: Translation initiation factor IF2/IF5 domain

phrase: EEGKELEVHIESISKKGDGVARIGKYILYVAGTKAGQNVKVRITRISGQVAF
type: DOMAIN
name: TRAM_dom
description: TRAM domain

phrase: ETGERFVMPKAKIYIEGKTTVLENFSDIVDSLNRDKDHFMKFILGELGTAGKIDGNRAVFNGKFEQAQFDAILETYVGDYVICSECGRPDTKLVKDDRVLMLLCEACGS
type: DOMAIN
name: Transl_init_fac_IF2/IF5_dom
description: Translation initiation factor IF2/IF5 domain

phrase: AIEEGKELEVHIESISKKGDGVARIGKYILYVAGTKAGQNVKVRITRISGQVAFTQKI
type: DOMAIN
name: TRAM_dom
description: TRAM domain
Protein sequence:
MTSEFFAAQLRAQISDDTTHPISYYKPEFYTPVDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSEILFNDEMDDFSSPNITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQPPSHADHTPMPQAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

Annotated regions:
phrase: TAHLSVVAEDGSAVSATSTINLYF
type: CONSERVED_SITE
name: GGT_CS
description: Gamma-glutamyltranspeptidase, conserved site
Protein sequence:
MAFNKLSIENLDLAGKRVLMRVDFNVPIKEGKITSNQRIVAALDSIKLALSKKAKSVVLMSHLGRPDGNKNIKYTLAPVAAELKTLLGQDVIFLSDCVGSEVEAACKDPAPGSVILLENVRFYVEEEGKGLDASGGKVKADPAKVKEFRASLAKLGDVYVNDAFGTAHRAHSSMMGDGFEQRAAGLLLNKELKYFSQALDKPPNPFLAILGGAKVADKIQLIENLLDKVNEMIIGGGMAFTFLKVLNNMKIGGSLFDEEGSKIVEKLVEKAKKNNVQLHLPVDFVCGDKFAENAAVSEATVEAGIPDGHMGLDVGPKTRELFAAPIARAKLIVWNGPPGVFEFPNFANGTKSIMDGVVAATKNGTVSIIGGGDTASCCAKWNTEALVSHVSTGGGASLELLEGKTLPGVAALTSA

Annotated regions:
phrase: RVLMRVDFNV
type: CONSERVED_SITE
name: Phosphoglycerate_kinase_CS
description: Phosphoglycerate kinase, conserved site
Protein sequence:
MRVKGIRKNWTHLWRWGTMLLGMLMICSTAEQLWVTVYYGVPVWKEATTTLFCASDAKAYETEKHNVWATHACVPTDPNPQEVVLENVTENFNMWRNDMVEQMQEDIISLWDQSLKPCVKLTPLCVTLNCTKYKRTENMTMEEGKMKNCSFNITSSIKDKIKKEYALFYAADIVPINNDSASYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGSGPCANVSTVQCTHGIRPVVSTQLLLNGSLAEEEVIVRSKNFTDNAKIIIVQLNESVVINCTRPNNNTRKSINMGPGRAFFAHGEIIGDIRQAHCNLSREQWNNTLKRIVIKLQEQFGNKTIIFNQSAGGDSEVVMHSFNCGGEFFYCNSTQLFNSSWSNDNSSWSNNTGRSTSNDTITLQCRIKQIINMWQKVGKAMYAPPIRGLIRCSSNITGLLLTRDGGNDSNINETFRPGGGDMRDNWRSELYKYKVVKIEPLGLAPTKAKRRVVQREKRAVGLGALFLGFLGAAGSTMGAASVTLTVQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLALERYLRDQQLLGIWGCSGKIICNTAVPWNMSWSNRSLEEIWENMTWMQWEKEIGNYTNQIYYLLEESQNQQEKNEQELLELDKWASLWNWFDITKWLWYIKIFIMIVGGLVGLRIIFAVLSIVNRVRQGYSPLSFQILSHHQREPDRPEGIEEGGGEQGRDRSVRLVSGFLALAWDDLRSLCLFSYHRLRDFILV

Annotated regions:
phrase: MGAASVTLTVQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLALERYLRDQQLLGIWGCSGKIICNTAVPWNMSWSNRSLEEIWENMTWMQWEKEIGNYTNQIYYLLEESQNQQEKNEQELLELDKWASLWNWFDITKWLWYIKIFIMIVGGLVGLRIIFAVLSIVNRVRQGYSPLSFQIL
type: DOMAIN
name: GP41-like
description: Retroviral envelope protein GP41-like

phrase: GKMKNCSFNITSSIKDKIKKEYALFYAADIVPINNDSASYRLISCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGSGPCANVSTVQCTHGIRPVVSTQLLLNGSLAEEEVIVRSKNFTDNAKIIIVQLNESVVINCTRPNNNTRKSINMGPGRAFFAHGEIIGDIRQAHCNLSREQWNNTLKRIVIKLQEQFGNKTIIFNQSAGGDSEVVMHSFNCGGEFFYCNSTQLFNSSWSNDNSSWSNNTGRSTSNDTITLQCRIKQIINMWQKVGKAMYAPPIRGLIRCSSNITGLLLTRDGGNDSNINETFRPGGGDMRDNWRSELYKYKVVKIEPLGLAPTKAKRRVVQREK
type: DOMAIN
name: HIV1_Gp120
description: Human immunodeficiency virus 1, envelope glycoprotein Gp120

phrase: LWVTVYYGVPVWKEATTTLFCASDAKAYETEKHNVWATHACVPTDPNPQEVVLENVTENFNMWRNDMVEQMQEDIISLWDQSLKPCVKLTPLCVTLNCTKYKRTE
type: DOMAIN
name: HIV1_Gp120
description: Human immunodeficiency virus 1, envelope glycoprotein Gp120

phrase: VQARQLLSGIVQQQNNLLRAIEAQQHMLQLTVWGIKQLQARVLALERYLRDQQLLGIWGCSGKIICNTAVPWNMSWSNRSLEEIWENMTWMQWEKEIGNYTNQIYYLLEESQNQQEKNEQELLELD
type: DOMAIN
name: GP41-like
description: Retroviral envelope protein GP41-like
Protein sequence:
MSKMPEEEEFYLFKNISSVGPWDGPQYHIAPVWAFQLQAAFMGIVFLAGLPLNSMVLVATVRYKKLRHPLNYVLVNVSVGGFLLCIFSVLPVFVNSCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALMVVLTTWTIGIGVSIPPFFGWSRYIAEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIVPLSLICFSYAQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAALAMYMVNNRNHGLDLRLVSIPAFFSKSSCIYNPIIYCFMNKQFRACIMEMVCGKAMTDESDISSSQKTEVSTVSSSQVGPN

Annotated regions:
phrase: LNSMVLVATVRYKKLRHPLNYVLVNVSVGGFLLCIFSVLPVFVNSCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALMVVLTTWTIGIGVSIPPFFGWSRYIAEGLQCSCGPDWYTVGTKYRSEYYTWFLFIFCFIVPLSLICFSYAQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAALAMYMVNNRNHGLDLRLVSIPAFFSKSSCIYNPII
type: DOMAIN
name: GPCR_Rhodpsn_7TM
description: GPCR, rhodopsin-like, 7TM

phrase: IPAFFSKSSCIYNPII
type: BINDING_SITE
name: Retinal_BS
description: Visual pigments (opsins) retinal binding site
Protein sequence:
MTQPVMNPENYQVQLDEKTEALSAMFSEFDVPELEVFSSPAENYRMRAEFRIWHEGDDMYYVMFDQKTKEKYRVDYFLPATRLINDLMPLLAEAIKGSKTLRYKMFQVDFLSTLSGEILVSMLYHRQLDDAWKEEAAVLKQQLNEKGFNLNLIGRARKMKIVLDQEFVIEKLKVNDDILTYKQVENSFTQPNGVVAQKMLEWAVDCTQDSQGDLLELYCGNGNFSLALAKNFDRVLATELAKPSVESAQYNIAANNIDNVQIVRMSAEDFTDAMEGKREFRRLKDQNVDLKSYNCNTIFVDPPRSGMDEGTCKMVQGYERIMYISCNPDTLKENLAILSKTHNITRFALFDQFPYTHHMEAGIFLERK

Annotated regions:
phrase: FDQFPYTHHM
type: CONSERVED_SITE
name: MeTrfase_TrmA_CS
description: RNA methyltransferase TrmA, conserved site

phrase: DPPRSGMDEGTCKMVQGYERIMYISCNPD
type: ACTIVE_SITE
name: MeTrfase_TrmA_AS
description: RNA methyltransferase TrmA, active site
Protein sequence:
MNMKKKEKHAIRKKSIGVASVLVGTLIGFGLLSSKEADASENSVTQSDSASNESKSNDSSSVSAAPKTDDTNVSDTKTSSNTNNGETSVAQNPAQQETTQSSSTNATTEETPVTGEATTTTTNQANTPATTQSSNTNAEELVNQTSNETTFNDTNTVSSVNSPQNSTNAENVSTTQDTSTEATPSNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSLAAVAADAPAAGTDITNQLTNVTVGIDSGTTVYPHQAGYVKLNYGFSVPNSAVKGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSDGNVIYTFTDYVNTKDDVKATLTMPAYIDPENVKKTGNVTLATGIGSTTANKTVLVDYEKYGKFYNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKPNTDSNALIDQQNTSIKVYKVDNAADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPNSKGDLALRSTLYGYNSNIIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPEDSDSDPGSDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSDNDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSESDSDSDSDSDSDSDSDSDSDSDSASDSDSGSDSDSSSDSDSESDSNSDSESGSNNNVVPPNSPKNGTNASNKNEAKDSKEPLPDTGSEDEANTSLIWGLLASIGSLLLFRRKKENKDKK

Annotated regions:
phrase: LPDTGSEDEANTSLIWGLLASIGSLLLFRRKKENKDK
type: DOMAIN
name: LPXTG_anchor
description: LPXTG cell wall anchor domain

phrase: SKEPLPDTGSEDEANTSLIWGLLASIGSLLLFRRKKEN
type: DOMAIN
name: LPXTG_anchor
description: LPXTG cell wall anchor domain

phrase: YPHQAGYVKLNYGFSVPNSAVKGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSDGNVIYTFTDYVNTKDDVKATLTMPAYIDPENVKKTG
type: DOMAIN
name: SDR_Ig
description: SDR-like Ig domain

phrase: KKKEKHAIRKKSIGVASVLVGTL
type: DOMAIN
name: YSIRK_signal_dom
description: YSIRK Gram-positive signal peptide

phrase: KFYNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVIAPVLTGNLKPNTDSNALIDQQNTSIKVYKVDNAADLSESYFVNPENFEDVTNSVNITFPNPNQYKVEFNTPDDQITTPYIVVVNGHIDPNSKGDLALRSTLYGYNSNIIWRSMSWD
type: DOMAIN
name: Adhesin_Fg-bd_dom_2
description: Fibrinogen-binding domain 2

phrase: MKKKEKHAIRKKSIGVASVLVGTLIGF
type: DOMAIN
name: YSIRK_signal_dom
description: YSIRK Gram-positive signal peptide
Protein sequence:
MFHHVTVLLEETVDQLNIDPNGIYVDCTLGGAGHSLYLVKQLQEGHLISIDQDQTAIDNAHIILKDYLDKVTFVKDNFRNLSDILAHLDIQKVDGILYDLGVSSPQLDVGERGFSYHQEAKLDMRMDQTQTLSAYEVVNTWPYEKLVSIFFRYGEEKFSKQIARKIEAERELKPIETTTELVEIIKAAIPAPARRTGGHPAKRVFQAIRIAVNDELGAFESSIEQAIDSVKPGGRISVITFHSLEDRLCKQVFQEYSKGPDIPRGLPVVPPEYQPKLKKITRKPITSSNEELEHNNRARSAKLRVVEILK

Annotated regions:
Protein sequence:
MAVIKMTDLDLKGKRVLLREDLNVPLKEGRITSDKRIRAALPSIRMAMEAGGRVLIVSHLGRPVEGEFDEAFSLAPVAAHLSRELGRDVRLVKDYIDGVDVAEGDCVLCENVRFLKGEKKNTEELGRRLAALCDIFVMDAFGAAHRAQASTHAVARFAPVACAGPLLAAELDALERALDAPKHPLVGIIGGSKVSTKLTLLDNLSHRVDRLIVGGGIANNFIKAAGYEVGKSLYEPELVEEAARLMAAARAAGGEIPVPLDVVVGPELADGAPATVRKVSEVGPDEMILDIGPATAALYREILLAAGTIVWNGPVGAFEWEQFGAGTRALCEAVADSPAFSIAGGGDTVAAVEKYGVASRVGYISTGGGAFLEFLEGKELPAVAILQERAAQS

Annotated regions:
phrase: RVLLREDLNV
type: CONSERVED_SITE
name: Phosphoglycerate_kinase_CS
description: Phosphoglycerate kinase, conserved site
Protein sequence:
MRAMQIPGHIDPVAVPRGEIARADGRVDVVGLTRAELREALIAAGIAEKQAKMRAQQIWHSIYNRGATDFSAMTSISKETQAQLAERFVIGRPEVVEAQVSTDGTRKWLLRSADGQDYEMVFIPDADRGTLCVSSQVGCTLNCRFCYTGTMKLVRNLTAGEVVAQVMLARDALGEWPSQPDGRLLTNIVMMGMGEPLYNFDNVKKALGIVMDGDGLSLSKRRITLSTSGVVPMMARAGEEIGVNLAVSLHAVTKEVRDEIVPINKKYGIEELLAACAAYPGANNARRITFEYVMLKGKNDSDDDARELVRLIRKYRLPAKVNLIPFNPWPGAAYECSDDDRIARFSDIIFKAGISAPVRTPRGRDIMAACGQLKSAAEKISRAELDRRAAEKEAAWTL

Annotated regions:
phrase: SSQVGCTLNCRFCYTGTMKLVRNLTAGEVVAQVMLARDALGEWPSQPDGRLLTNIVMMGMGEPLYNFDNVKKALGIVMDGDGLSLSKRRITLSTSGVVPMMARAGEEIGVNLAVSLHAVTKEVRDEIVPINKKYGIEELLAACAAYPGANNARRITFEYVMLKGKNDSDDDARE
type: DOMAIN
name: rSAM
description: Radical SAM

phrase: DADRGTLCVSSQVGCTLNCRFCYTGTMKLVRNLTAGEVVAQVMLARDALGEWPSQPDGRLLTNIVMMGMGEPLYNFDNVKKALGIVMDGDGLSLSKRRITLSTSGVVPMMARAGEEIGVNLAVSLHAVTKEVRDEIVPINKKYGIEELLAACAAYPGANNARRITFEYVMLKGKNDSDDDARELVRLIRKYRLPAKVNLIPFNPWPGAAYECSDDDRIARFSDIIFKAGISAPVRTPRGR
type: DOMAIN
name: rSAM
description: Radical SAM

phrase: DVVGLTRAELREALIAAGIAEKQAKMRAQQIWHSIYNRGATDFSAMTSISKETQAQLAERFV
type: DOMAIN
name: RlmN_N
description: Dual-specificity RNA methyltransferase RlmN, N-terminal domain
Protein sequence:
MMIALLFLIISEAGGLLTPASHACRVGSSYFLTNCCAPRDVAFCLEGGCVVALGCTVCTDVCWPILRPGISVRPGVDSSALVGQLGSLYSPLAVGSYAAGVLGLGEVYSGALALGVLVTRHAYPLPNLTCAVECEMEWGNEFWRWTQEVASQYWILEYLWRLPFDFWKGVMALDVLLAFVAALLLLEQRLVMLFLLVTTAGMAASRPTGDLGARPFVPGPGWRCTCYEDGSRVPTDKQVWERGNKTLLCDCPNGPWVWLPSICGGVAWGSGVVKTWSHGQNQWPLSCPRYVHGHITATCVWGSRSWFTSTRGDGTIDLWSLVSTGSALCTIAVLGTSDRDVVPGLSTFGIPCVSCVVDRRPPSCGGCVRDCWPETGEFGTPFAKCGLGPRLTEHLVAIPFVNRSVPFQIRGPLGFQGSGNPLRNPLRGGTFTMTLIDGSLHLVECPTPPPAHPEGTYGFFPGAPPVNNCFLLGSEVSEELGGAGLTGGAFEPLVRRCSLLSGKRHTVCPGFAWVSSSRPDGFIHVKGGVQEVDDHSWAPPPRWLLLDFVFVLLYLMKLAEARLVPLILLLLWWWLNQLAALGAVAGEVFAAPLASWCLTLPWVAMILGLVNLVLYLRWLGTTRLVLLLAWKLARGAFPLALLMGISATRGRTSVLGAQFCLDVTVDMEPTILGWVLASLIAWSIALLATMSAGGWRHKAAVYRLWCKGHQWLRRRIVDSPIGEGRPTTPAVAAWCLAAYFWPDAVMWVVVALVVVLGLVDALDWALEE

Annotated regions:
phrase: ILGWVLASLIAWSIALLATMSAGGWRHKAAVYRLWCKGHQWLRRRIVDSPIGEGRPTTPAVAAWCLAAYFWPDAVMWVVVALVVVLGLVDALDW
type: DOMAIN
name: HCV_NS2
description: Hepatitis C virus, Non-structural protein NS2

phrase: HAYPLPNLTCAVECEMEWGNEFWRWTQEVASQYWILEYLWRLPFDFWKGVMALDVLLAFVAALLLLEQRLVMLFLLVTTAGMAASRPTGDLGARPFVPGPGWRCTCYEDGSRVPTDKQVWERGNKTLLCDCPNGPWVWLPSICGGVAWGSGVVKTWSHGQNQWPLSCPRYVHGHITATCVWGSRSWFTSTRGDGTIDLWSLVSTGSALCTIAVLGTSDRDVVPGLSTFGIPCVSCVVDRRPPSCGGCVRDCWPETGEFGTPFAKCGLGPRLTEHLVAIPFVNRSVPFQIRGPLGFQGSGNPLRNPLRGGTFTMTLIDGSLHLVECPTPPPAHPEGTYGFFPGAPPVNNCFLLGSEVSEELGGAGLTGGAFEPLVRRCSLLSGKRHTVCPGFAWVSSSRPDGFIHVKGGVQEVDDHSWAPPPRWL
type: DOMAIN
name: GB_virus_envelope
description: GB virus, envelope protein
Protein sequence:
MKHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALSELYHPTQVLGDLLTIKEWNKMQNGIAKVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNYKISPEIWEFAMKQALISGAKISLSHDKFEALKDKDVVITDTWVSMGEENEKERKIKEFEGFMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCFLDNQRGRE

Annotated regions:
phrase: KVAFIGDSNNMCNSWLIAAAILGFEFSIAIPKNYKISPEIWEFAMKQALISGAKISLSHDKFEALKDKDVVITDTWVSMGEENEKERKIKEFEGFMIDEKAMSVANKDAILLHCLPAYRGYEVSEEIFEKHADVIFEEARNRLYVVKALLCF
type: DOMAIN
name: Asp_carbamoyltransf_Asp/Orn-bd
description: Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain

phrase: KHFLTLRDFSKEEILSLVNHASELKKEPKKLLQDKTLAMIFEKNSTRTRMAFELAITELGGKALFLSSNDLQLSRGEPVKDTARVIGAMVDFVMMRVNKHETLLEFARYSKAPVINALSELYHPTQVLGDLLTIK
type: DOMAIN
name: Asp/Orn_carbamoyltranf_P-bd
description: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding
Protein sequence:
MELKQLFKNIDFELKQGNLNQKITEVKYDSREIEKDNLFIAINGFEVDGHQFIEQAIKNGAAAVVIEKDLSEYQTGISYIKVDNCRKVMAELAKNFFGNPLKDIKLIGITGTNGKTTTSYLLYNILKEAKGKAALFGTIKNIIGEQELDSSRTTPESVDLYRYFSQMREAEVKYGVMEVSSHALDLYRVYGMKFAAAIFTNISPEHLDYHKNLENYREVKARLFAQLSQAEFAVINLDDSNSDYIKEKSGGKNYFYSLNAKTADLYTTDYELHQKGMEYRTGGKLDTFFELNLGGIFNIYNSLASILTAKLLGIKKDTIKNALAKISSVPGRFEIINAGQDFQIVVDYAHTPDGMKNVLETASAMEKNRLIVLFGCGGDRDRSKRPVMASLAEKYTDYTIVSNDNPRSEDPENIFAEIKKGFSKKFNAYEIIPDRKKAIEKAIQIAEKNDLVMLLGRGHEQYQILKNRKIKLDDRQIAHQAAVEMKGI

Annotated regions:
phrase: IGITGTNGKTTTSYLLYNILKEAK
type: CONSERVED_SITE
name: Folylpolyglutamate_synth_CS
description: Folylpolyglutamate synthetase, conserved site

phrase: GRFEIINAGQDFQIVVDYAHTPDGMKNVLETASAMEKNRLIVLFGCGGDRDRSKRPVMASLAEKYTDYTIVSNDNPRSEDPENIFAEIKKGFSKKFNAYEIIPDRKKAIEKAIQIAEKNDLVMLLGR
type: DOMAIN
name: Mur_ligase_C
description: Mur ligase, C-terminal

phrase: ITGTNGKTTTSYLLYNILKEAKGKAALFGTIKNIIGEQELDSSRTTPESVDLYRYFSQMREAEVKYGVMEVSSHALDLYRVYGMKFAAAIFTNISPEHLDYHKNLENYREVKARLFAQLSQAEFAVINLDDSNSDYIKEKSGGKNYFYSLNAKTADLYTTDYELHQKGMEYRTGGKLDTFFELNLGGIFNIYNSLASIL
type: DOMAIN
name: Mur_ligase_cen
description: Mur ligase, central

phrase: KITEVKYDSREIEKDNLFIAINGFEVDGHQFIEQAIKNGAAAVVIEKDLSEYQTGISYIKVDNCRKVMAELAKN
type: DOMAIN
name: Mur_ligase_N
description: Mur ligase, N-terminal catalytic domain
Protein sequence:
MQNLLKIGKYELGSRLIVGSGKYKDFQTTKEATLASGSELITVAVRRLNITDPNKENLRDTFKGTNVKFLPNSAGCVTAEEAITTFRLTREATGIDLIKLEVIGDTQKTLYPDVIETIKACQILSKEGFIIMAYTSDDPIMAKRLEDAGAHAIMPLAAPIGSGLGIQNPYNIVFIREAVNLPVIVDAGIGCASDAAYAMELGADGVLTNTAIAGAQNPMMMAEAMKHAVIAGRMSYLSGRIQKRPYATASSPINGMIQF

Annotated regions:
phrase: KIGKYELGSRLIVGSGKYKDFQTTKEATLASGSELITVAVRRLNITDPNKENLRDTFKGTNVKFLPNSAGCVTAEEAITTFRLTREATGIDLIKLEVIGDTQKTLYPDVIETIKACQILSKEGFIIMAYTSDDPIMAKRLEDAGAHAIMPLAAPIGSGLGIQNPYNIVFIREAVNLPVIVDAGIGCASDAAYAMELGADGVLTNTAIAGAQNPMMMAEAMKHAVIAGRMSYLSGRIQKRPYATASS
type: DOMAIN
name: Thiazole_synthase_ThiG
description: Thiazole synthase ThiG
Protein sequence:
MLLKSLFLLFLTAIAFASELQIGILTSVPDDKCKVKSKPGDLISVHYEGKLEDGTVFDSSYSRGQPISFQLGIGQVIQGWDQGLTRMCIGEKRKLTIPSHLAYGDRGVGPIPAKATLVFVAELVDIAGSSKHDEL

Annotated regions:
phrase: CKVKSKPGDLISVHYEGKLEDGTVFDSSYSRGQPISFQLGIGQVIQGWDQGLTRMCIGEKRKLTIPSHLAYGDRGVGPIPAKATLVFVAEL
type: DOMAIN
name: PPIase_FKBP_dom
description: FKBP-type peptidyl-prolyl cis-trans isomerase domain

phrase: GDLISVHYEGKLEDGTVFDSSYSRGQPISFQLGIGQVIQGWDQGLTRMCIGEKRKLTIPSHLAYGDRGVGPIPAKATLVFVAELVDI
type: DOMAIN
name: PPIase_FKBP_dom
description: FKBP-type peptidyl-prolyl cis-trans isomerase domain
Protein sequence:
MKEPLDLSKYSVRTDLAVEAHQMLQERQEEQKGIQGVIVKEREEEGVTITKVTIDEIASESMGKKPGSYLTLEVQGIRQQDTELQQKVERIFAKEFSYFLEEVGVSKEASCLIVGLGNWNVTPDALGPIVVENVLVTRHLFKLQPESVEEGFRPVSAIRPGVMGITGIETSDVIYGIIEKTKPDFVIAIDALAARSIERVNSTIQISDTGIHPGSGVGNKRKELSKETLGIPVIAIGVPTVVDAVSITSDTIDFILKHFGRELKEGNKPSRSLLPAGFTFGEKKKLTEEDMPDEKSRNMFLGAIGTLEEEEKRKLIYEVLSPLGHNLMVTPKEVDAFIEDMANVIASGLNAALHHQIDQDNTGAYTH

Annotated regions:
Protein sequence:
MAPQTCAICQKAKAMVKRPKTGEQICRECFFYVFETEVHNTITQANLFKPGDRVAIGASGGKDSTVLAYVMKMLNERYQYGLELFLLSIDEGITGYRDDSLETVKRNQQQYDMPLKILSYDELYGWTMDAIVSQVGRKNNCTFCGVFRRQALDRGAAMLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTQGEDTIRRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPDAYRGHARVFLKDLEAARPSAIIDIIHSGEAFEVREEVKATQRVQQVCQRCGYMSSNALCKACTLLEGLERGMANSGITDRARKKLDAEGPAPDNLRTIPFFKPPSGGPLIAIESVS

Annotated regions:
phrase: VCQRCGYMSSNALCKACTLLEGLERGMA
type: DOMAIN
name: CTU1_C
description: Cytoplasmic tRNA 2-thiolation protein 1, C-terminal

phrase: VAIGASGGKDSTVLAYVMKMLNERYQYGLELFLLSIDEGITGYRDDSLETVKRNQQQYDMPLKILSYDELYGWTMDAIVSQVGRKNNCTFCGVFRRQALDRGAAMLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTQGEDTIRRSKPFKYAYEKEIVMYAYFKKLDYFST
type: DOMAIN
name: TilS/TtcA_N
description: tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal

phrase: FETEVHNTITQANLFKPGDRVAIGASGGKDSTVLAYVMKMLNERYQYGLELFLLSIDEGITGYRDDSLETVKRNQQQYDMPLKILSYDELYGWTMDAIVSQVGRKNNCTFCGVFRRQALDRGAAMLNVDHIVTGHNADDIAETVLMNIMRGDIARLGRCTSICTQGEDTIRRSKPFKYAYEKEIVMYAYFKKLDYFSTECIYSPD
type: DOMAIN
name: CTU1-like_ATP-bd
description: Cytoplasmic tRNA 2-thiolation protein 1-like, ATP-binding domain
Protein sequence:
MRALFYKDGKLFTDNNFLNPVSDNNPAYEVLQHVKIPTHLTDVVVYGQTWEEALTRLIFVGSDSKGRRQYFYGKMHVQNRNAKRDRIFVRVYNVMKRINCFINKNIKKSSTDSNYQLAVFMLMETMFFIRFGKMKYLKENETVGLLTLKNKHIEISPDKIVIKFVGKDKVSHEFVVHKSNRLYKPLLKLTDDSSPEEFLFNKLSERKVYECIKQFGIRIKDLRTYGVNYTFLYNFWTNVKSISPLPSPKKLIALTIKQTAEVVGHTPSISKRAYMATTILEMVKDKNFLDVVSKTTFDEFLSIVVDHVKSSTDG

Annotated regions:
phrase: LFYKDGKLFTDNNFLNPVSDNNPAYEVLQHVKIPTHLTDVVVYGQTWEEALTRLIFV
type: DOMAIN
name: TopoI_N_vir
description: DNA topoisomerase I, N-terminal, viral

phrase: YNVMKRINCFINKNIKKSSTDSNYQLAVFMLMETMFFIRFGKMKYLKENETVGLLTLKNKHIEISPDKIVIKFVGKDKVSHEFVVHKSNRLYKPLLKLTDDSSPEEFLFNKLSERKVYECIKQFGIRIKDLRTYGVNYTFLYNFWTNVKSISPLPSPKKLIALTIKQTAEVVGHTPSISKRAYMA
type: DOMAIN
name: TopoI_cat_euk
description: DNA topoisomerase I, catalytic core, eukaryotic-type

phrase: NRNAKRDRIFVRVYNVMKRINCFINKNIKKSSTDSNYQLAVFMLMETMFFIRFGKMKYLKENETVGLLTLKNKHIEISPDKIVIKFVGKDKVSHEFVVHKSNRLYKPLLKLTDDSSPEEFLFNKLSERKVYECIKQFGIRIKDLRTYGVNYTFLYNFWTNVKSISPLPSPKKLIALTIKQTAEVVGHTPSISKRAYMATTILEM
type: DOMAIN
name: TopoI_cat_euk
description: DNA topoisomerase I, catalytic core, eukaryotic-type

phrase: EVVGHTPSISKRAYMATT
type: ACTIVE_SITE
name: TopoI_AS
description: DNA topoisomerase I, active site