Protein sequence:
MVVTLTKLERLQKAEKSRTFKPLIDELINCEDAVFVGKLEAIREWDRPKDDLFLWIPVLDRMDDMLGKVVAKYKYHTTDCKRHPVKLIEMAKPDEDWVATLLFFTCRLLNNTSNRSLYSSLDMMSDLLNCPNFRVKLGAMKVIATIGERHVVARHRIENSSVLASQHLKKRSLSLALALPSSTTDDNSDHFSLVDLFFDKRKYPSKWSQLQYTYYITKKQAGQQSTQKPSQVSSMKRFVLNNEELRFLSLQQIFDRAMNDLPSEFWFDFSLQASIAKAFSDDSFENIQLRSLIIQTKFAAIAFANAIYIPPQVSSKLFEMDPYAFNNLTDFISLSETKIPKDLRTDALFALECISLKHVWCSDIVRNLGGNMSHGLLFQILRYIAKVLREGDEDAVDEEYNVRFFYLISNLADVKALQESLISAGLISSLLEIVSTQNSKYKRTLASAAHLLEDVISDADATAEFINNNGFNILIQTVTYEVNFAVQNPSSAEPPKYSVVYYSISFRQLGFIRSLLKLVLKLLKTDSGDRIRNLIDSPILLAFNKILENRPVFGYTLVSHALDVVQTIINTEPTIYQVLVESGTIPYILQNFDQFLGPTSDLLCMLPEVISAICLNTDGLKQVKEKNLLKYLFQVIKTPEFAKILSWEDQAVNYGVALDELARHYPELKPLIEDYFAATVKELPSLTSYTHSYLYESTAGNGEFYLSENETIIDNEDGADELAFWEVQESSPIIDCFSGVFYSMASENISWANLTEKIAFQDFLSVAIPEKPTFDYINSQTLLNFTDVLKMFDDERRSYALPELLTILDSKFADLEDFLSYDFTKSYVLNEPKDRVVATLNKLNVLNVILYIMTDIYINITTLFPVRVIQMMEFFEKNGFNLITNLRKMFQRCVLEEMYIRSRLPPAVAEETISPGISFVPPILIHKDVPLKTEAKQEKTSAKFKNTLETRHLFQKVQSWTSMLFRCFLRLTHARKMNVERYDRALEIRIFDKVVNEIVEMLNLDYLDSHLSYFLVVLDFNTHIFTCPKASLTISDGIVQTVPTFLFYQAGGFAIYHELIKKLSTRLLGFDGIEAIEKVEYVKDQDDILTVGVLMNSIAFMNRCIQLETMENIRSIAEYYPYDDIYYNLTRALIVPVKILSLGAISEIFSQGEVFDTDRRRIPYSVFKQILSLLKNIYNSTFELEEGTDVYELRWDLMPISHRKVEMLKSCGISHDVAVGYLEEEKDELPIHVKPDVFSDSEWQRYQEERSSGSWRTNIELLPPQYNGSSTRETLSKMRTEFYQNGFESGILKILQHYPKLINAISHMFFEMYGELGFSHTTMLEDLQDMMNTIPIENTNKLAPVIHLFGIFLNDKNIYDQAKKEIFKFVSYLSMNLHPENVNYSWFSKALYVYEIIFAKSETPEASPLPENVTVSFSSIPIIYRISQKDKDIIFNLLIRANEVTDFYSALAISRILILYTREERYAQEVTQSGILSKLLKVIGANQKFDKINYLESSYLLLVRRCFETKEIVTSLIDYELTRAFTTRAIGDHKEKPRDLPALVNEKASIVMRDPEVFVNRISETARFEDFNSSKELASLSVRRHMDEKDEEMTSKPLSSEGSNSPITGIVHLLLSQLMAAHKRDWVSETPLTPEEENQKNKKKKDEVKVSKNPVCAYMIFLLKVLTELVSSYKQSKFEFLTYNKKNVYNETPKPRATALNFFLYQLLDTNFQDMDKHEGKRRAMISGLARDTIIGFVSSVQDSETKKVDPKIVDSDMTYIRKFTIEAISKAIKEAGVSAKTIDANAGKLFGWFHLISSLLVVDKGYIFSVLDSNKSSNDKYQLCKLLIEMNTPGTITDCMASLDLNYPLTKKLFNSAVEPLNALNEVRNNFADLFKLENNEDEDVEDVESDKDDVPDMFKNSALGMYDIEDVEDDHDDDENESLIGDDEDIAFVHDEDGLEVVFSEDEDANEDTTDASNSIGSDSEGNSDFGGSGPNVTLEVYTDSEDAIEDVNTAAIRITSGNSAEHSYYSEGEDSAEIEIYEEEYDSEIDIDMDDDSELGSSNWESGLSDLSDSEAYSDEERTNNTGDGFVRWYSDDGVEFEDDTDEEGRGLFTGIQHVFPTEEQLFRVHASGAARSTGRHHHRHGAAPFTTSTITLGASQRRPHSILSNPLGPSGLEEVENDIVSHYLGNVETSDRIGLSSIPRLPRVLLFDGELFDDKSSSGILLKSTTARWNDIYEMFYDSKVYSNNVVTTIISRIFEPSAELYLKEQEENAVKESSRINEPTRRQDERKRKLHEIDSDEEHIEEEEEHDEVVEPIEAPGINSPQARAPQEPVYVTIDGEAVNIAGTDMDAEFLNALPDDIRAEVFAQHIREYRTQFQGSEGSSRELDAGFLNTIPETLRQEILAQEVPLERNARPSILGLRNREGEEFSEVEDESPRFNEQRTESSKTKTDRVHFAPLLDRSGIAAIMKAVFIPQPYLSREIYHELFYRLCSSKQNRSDIMNMLLLILMDGINDQHSLERVYNLLSNRAASSNSGTSKTPQRQLPPDCTPLIVTNQCIEILQSMVDADSKLKYFFITEHENLLINKSPLKNKKDIFSKNMKWPINCILALLEKKVITDEAVLMDLLTRILQVCSKPISSIVKSSKDGKKKKFEVPDIEKKYLASIVSIIKLDSCNTKVFQQTLNLMTNLFAIKDAHETFTTELCNLAKETIEVLVTDLDALAKEVPAVDSGTEVSSEIIQKFTVPSSDQSKLLKVLTAIDYIYVNRKKEEEQVVDQLLPLYNKMELGHIWVSLSNCLTRFEEKPRMSTSATILLPLIESLMVVCKHSKVRETKDALLKYEAKKCDFARTPVENLFFAFTDLHKKLLNEMIRSNPKLMSGPFSLLVKNPKILDFDNKRYYFTAQLRAITHDRPKLSISVRREHVFLDSYRSLFFKSNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYALFIPVASDKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDDYGEHKVIELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFGIA

Annotated regions:
phrase: LSISVRREHVFLDSYRSLFFKSNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYALFIPVASDKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDDYGEHKVIELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGF
type: DOMAIN
name: HECT_dom
description: HECT domain

phrase: FKSNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYALFIPVASDKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDDYGEHKVIELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFGI
type: DOMAIN
name: HECT_dom
description: HECT domain

phrase: SNEDIKISKLEISFKGEAGVDAGGITREWYQVLSRQMFNPDYALFIPVASDKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDDYGEHKVIELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFGI
type: DOMAIN
name: HECT_dom
description: HECT domain

phrase: VLSRQMFNPDYALFIPVASDKTTFRPNRTSGINPEHLSFFKFIGMIIGKAISDQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDDYGEHKVIELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAIIPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEERAKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSYETLRGSLLLAINEGHEGFG
type: DOMAIN
name: HECT_dom
description: HECT domain

phrase: DEDWVATLLFFTCRLLNNTSNRSLYSSLDMMSDLLNCPNFRVKLGAMKVIATIGERHVVARHRIENSSVLASQHLKKRSLSLALALPSSTTDDNSDHFSLVDLFFDKRKYPSKWSQLQYTYYITKKQAGQQSTQKPSQVSSMKRFVLNNEELRFLSLQQIFDRAMNDLPSEFWFDFSLQASIAKAFSDDSFENIQLRSLIIQTKFAAIAFANAIYIPPQVSSKLFEMDPYAFNNLTDFISLSETKIPKDLRTDALFALECISLKHVWCSDIVRNLGGNMSHGLLFQILRYI
type: DOMAIN
name: E3_Ub_ligase_DUF908
description: E3 ubiquitin ligase, domain of unknown function DUF908

phrase: NIAGTDMDAEFLNALPDDIRAEVFAQHIR
type: CONSERVED_SITE
name: HUWE1/Rev1_UBM
description: HUWE1/REV1, ubiquitin-binding motif

phrase: FLNTIPETLRQEILAQEV
type: CONSERVED_SITE
name: HUWE1/Rev1_UBM
description: HUWE1/REV1, ubiquitin-binding motif

phrase: AHLLEDVISDADATAEFINNNGFNILIQTVTYEVNFAVQNPSSAEPPKYSVVYYSISFRQLGFIRSLLKLVLKLLKTDSGDRIRNLIDSPILLAFNKILENRPVFGYTLVSHALDVVQTIINTEPTIYQVLVESGTIPYILQNFDQFLGPTSDLLCMLPEVISAICLNTDGLKQVKEKNLLKYLFQVIKTPEFAKILSWEDQAVNYGVALDELARHYPELKPLIEDYFAATVKELPSLTSY
type: DOMAIN
name: E3_Ub_ligase_DUF913
description: E3 ubiquitin ligase, domain of unknown function DUF913