Protein sequence:
MKSPRFRHSQKYIGSKPYYGYYENDHYIVSWCRGHLLELKNPEEMDPKYKLFQLEHLPLIFQPSYKVIQENAEQLQILVKLLQRPDVDHAVNICDADREGELIYREVYEYAGVNKKQSRVYKSSFEAAELEAALNRLESASKYDGLAYSAKARQYLDYLLGMNITRGCTTKLAQNKFLLSSGRVQMCLLHEIRQRELAIENYREQSYYHLQLITDLGLKPVMKTEDQVLNPSPLKSLGENLKDQYLTVEDFKEGTRKQNPKLLYNLTDLYKDAHAQLQINAETAKKHIQNLYEEGFITYPRSSSRHLPTEQVDRVKGVMQALAKSRYSLLVQSVDIDAIDIKHKTFDDDLVSSHFAIIPTTKQYQEEGRPEIEKQLYSLVVKRFVGNFMRPAVYLVRDVSLIDAMGNTYQIKESVLREKGFLEVFQEEVKEESVETFKVPILQKGQELQIYDFELQESKTKKPALHTESSILTFMETAGRKIDDEHLKELMKGKRIGTVATEAAFIPVLHEKNFIDIEKGKIITTPIGRAFIEQFPVQQIKDPLYTAEMEGMIHRIEKNEMSYENFIAQTNAFVQKITQEIIRIPDTVSYNLIETWKKQIEVCQCPCGNGIILDRGKFFGCSNHPNCNKGLPKRVKEKTIPTAQVKKLFEENKTDIIKGFKSNGKEFSAYLAFVNGEVSFNLPSVEELSLGQCPKCQKGKILNRKTFFGCSEYQNGCDFMLPAKIKGKKLSDSQIKKLVNNHVTDFINGFSGEKGEFTAAIRLKTDLSICFEFPTTDDRTVGKCPLCQSRVIIGKTNYLCEQYKRGCDFIVSGMILEKRITASQIKKLLEKNMTDTVKGFVSKKTGKSFDAKLTYDSTQKRVTFIYEKKK

Annotated regions:
phrase: KQSRVYKSSFEAAELEAALNRLESASKYDGLAYSAKARQYLDYLLGMNITRGCTTKLAQNKFLLSSGRVQMCLLHEIRQRELAIENYREQSYY
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: AVNICDADREGEL
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LSSGRVQMCLLHEIRQRE
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: EGFITYPRS
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LYSLVVKRFVGNFMRP
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: RIGTVATEAAFIPV
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: YDGLAYSAKARQYLDYLLGMNITRGCTTKLAQNKFLLSSGRVQMCLLHEIRQRELAIENYREQSYYHLQLITDLGLKPVMKTEDQVLNPSPLKSLGENLKDQYLTVEDFKEGTRKQNPKLLYNLTDLYKDAHAQLQINAETAKKHIQNLYEEGFITYPRSSSRHLPTEQVDRVKGVMQALAKSRYSLLVQSVDIDAIDIKHKTFDDDLVSSHFAIIPTTKQYQEEGRPEIEKQLYSLVVKRFVGNFMRPAVYLVRDVSLIDAMGNTYQIKESVLREKGFLEVFQEEVKEESVETFKVPILQKGQELQIYDFELQESKTKKPALHTESSILTFMETAGRKIDDEHLKELMKGKRIGTVATEAAFIPVLHEKNFIDIEKGKIITTPIGRAFIEQFPVQQIKDPLYTAEMEGMIHRIEKNEMSYENF
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GCDFMLPAKIKGKKLSDSQIKKLVNNHVTDFINGFSGEKGEFTAAIRLKTDLSICFEF
type: REPEAT
name: Toprim_C_rpt
description: Topoisomerase C-terminal repeat

phrase: CNKGLPKRVKEKTIPTAQVKKLFEENKTDIIKGFKSNGKEFSAYLAFVNGEVSF
type: REPEAT
name: Toprim_C_rpt
description: Topoisomerase C-terminal repeat

phrase: GCDFIVSGMILEKRITASQIKKLLEKNMTDTVKGFVSKKTGKSFDAKLTYDSTQKRVTFI
type: REPEAT
name: Toprim_C_rpt
description: Topoisomerase C-terminal repeat

phrase: KPYYGYYENDHYIVSWCRGHLLELKNPEEMDPKYKLFQLEHLPLIFQPSYKVIQENAEQLQILVKLLQRPDVDHAVNICDADREGELIYREVYEYAGVNKKQSRVYKSSFEAAELEAALNR
type: DOMAIN
name: TOPRIM_TopoIII
description: DNA topoisomerase 3-like, TOPRIM domain

phrase: MKSPRFRHSQKYIGSKPYYGYYENDHYIVSWCRGHLLELKNPEEMDPKYKLFQLEHLPLIFQPSYKVIQENAEQLQILVKLLQRPDVDHAVNICDADREGELIYREVYEYAGVNKKQSRVYKSSFEA
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: NDHYIVSWCRGHLLELKNPEEMDPKYKLFQLEHLPLIFQPSYKVIQENAEQLQILVKLLQRPDVDHAVNICDADREGELIYREVYEYAGVNKKQSRV
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: GLAYSAKARQYLDYLLGMNITRGCTTKLAQNKFLLSSGRVQMCLLHEIRQRELAIENYREQSYYHLQLITDLGLKPVMKTEDQVLNPSPLKSLGENLKDQYLTVEDFKEGTRKQNPKLLYNLTDLYKDAHAQLQINAETAKKHIQNLYEEGFITYPRSSSRHLPTEQVDRVKGVMQALAKSRYSLLVQSVDIDAIDIKHKTFDDDLVSSHFAIIPTTKQYQEEGRPEIEKQLYSLVVKRFVGNFMRPAVYLVRDVSLIDAMGNTYQIKESVLREKGFLEVFQEEVKEESVETFKVPILQKGQELQIYDFELQESKTKKPALHTESSILTFMETAGRKIDDEHLKELMKGKRIGTVATEAAFIPVLHEKNFIDIEKGKIITTPIGRAFIEQFPVQQIKDPLYTAEMEGMIHRIEKNEMSYENFIAQTNAFVQK
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: QNLYEEGFITYPRS
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site

phrase: QKYIGSKPYYGYYENDHYIVSWCRGHLLELKNPEEMDPKYKLFQLEHLPLIFQPSYKVIQENAEQLQILVKLLQRPDVDHAVNICDADREGELIYREVYEYAGVNK
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: KEGTRKQNPKLLYNLTDLYKDAHAQLQINAETAKKHIQNLYEEGFITYPRSSSRHLPTEQVDRVKGVMQALAKSRYSLLVQSVDIDAIDIKHKTFDDDLVSSHFAIIPTTKQYQEEGRPEIEKQLYSLVVKRFVGNFMRPAVYLVRDVSLIDAMGNTYQIKESVLREKGFLEVFQEEVKEESVETFKVPILQKGQELQIYDFELQESKTKKPALHTESSILTFMETAGRKIDDEHLKELMKGKRIGTVATEAAFIPVLHEKNFIDIEKGKIITTPIGRAF
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain