Protein sequence:
MEPFVVKENIIASASSPMKKRRIDHTESADGSAINASNSSSIGLNNSIGGNDTVMSMAEFGNDNSNNQEIDEDLHSRQLAVYGRETMRKLFASNVLISGMQGLGVEIAKNIILAGVKSVTLHDENVVELWDLSSNFVFTEEDIGKNRALASVHKLQELNNAVAVSTLTGKLTKEQLSDFQVVVFVDISFEKATEIDDYCHSHQPPIAFIKADVRGLFGSLFCDFGPHFTVLDVDGEEPHSGIIASVSNENPGFVSCVDDERLEFEDGNLVVFSEVEGMTELNDGKPRKIKNVKPFSFTLEEDTSSYGQYMKGGIVTQVKQPKVLNFKPLREALKDPGDFLLSDFSKFDRPPLLHLAFQALDRFSSQAGRFPFAGSEEDAQKLVEIAVDINEGLGDARLEDVNSKLLRHLAFGSRAVLNPMAAMFGGIVGQEVVKACSGKFHPIFQFFYFDSVESLPKEPLDASEFRPQNSRYDAQISVFGSTLQKKLEDARVFVVGAGALGCEFLKNLALMGVSCGTQGKLTVTDDDVIEKSNLSRQFLFRDWNIGQAKSTVAATAAAGINSRLNIDALQNRVGPETENVFDDSFWENLTVVVNALDNVTARLYVDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAYLSDPVEYMKAMRTAGDAQARDTLGRVVECLEKEKCNSFQDCITWARLRFEDYFANRVKQLCYTFPEDAATSTGAPFWSAPKRFPRPLQFSSTDLSHINFVMAASILRAETFGIPTPEWAKTRAGLAEAVERVIVPDFEPKKDATIVTDEKATTLSTASVDDAAVIDELNAKLVRCRMSLQPEFRMKAIQFEKDDDTNYHMDMIAGLANMRARNYSVPEVDKLKAKFIAGRIIPAIATSTAMATGFVCLEMYKVLDGSHKVEDYRNTFANLALPLFSMAEPVPPKVVKHQDQSWTVWDRWVMRGNPTLRELLDWLKEKGLNAYSISCGSSLLYNSMFSRHKERMNRRVVDLARDVAGVELPAYRRHVDVVVACEDDNDADVDIPLVSVYFA

Annotated regions:
phrase: KACSGKFH
type: CONSERVED_SITE
name: UBQ-activ_enz_E1_CS
description: Ubiquitin-activating enzyme E1, conserved site

phrase: PHNIDHCLTWARSEFEGLLEKTPAEVNAYLSDPVEYMKAMRTAGDAQARDTLGRVVECLEKEKCNSFQDCITWARLRFEDYFANRVKQLCYTFPEDAATSTGAPFWSAPKRFPRPLQFSSTDLSHINFVMAASILRAETFGIPTPEWAKTRAGLAEAVERVIVPDFEPKKDATIVTDEKATTLSTASVDDAAVIDELNAKLVRCRMSLQPEFRMKAIQFEKDDDTNYHMDMIAGLANMRARNYSVPEVDKLKA
type: DOMAIN
name: UBA_E1_SCCH
description: Ubiquitin-activating enzyme, SCCH domain

phrase: PMCTVHSF
type: ACTIVE_SITE
name: UBQ-activ_enz_E1_Cys_AS
description: Ubiquitin-activating enzyme E1, Cys active site

phrase: ENPGFVSCVDDERLEFEDGNLVVFSEVEGMTELNDGKPRKIKNVKPFSFTLEEDTSSYGQYMKGGIVTQV
type: DOMAIN
name: E1_FCCH
description: Ubiquitin-activating enzyme E1, FCCH domain

phrase: YRNTFANLALPLFSMAEPVPPKVVKHQDQSWTVWDRWVMRGNPTLRELLDWLKEKGLNAYSISCGSSLLYNSMFSRHKERMNRRVVDLARDVAGVELPAYRRHVDVVVACEDDNDADVDIPL
type: DOMAIN
name: Ub-activating_enz_E1_C
description: Ubiquitin-activating enzyme E1, C-terminal

phrase: QPKVLNFKPLREALKDPGDFLLSDFSKFDRPPLLHLAFQALDRFSSQAGRFPFAGSEEDAQKLVEIAVDI
type: DOMAIN
name: E1_4HB
description: Ubiquitin-activating enzyme E1, four-helix bundle

phrase: YDAQISVFGSTLQKKLEDARVFVVGAGALGCEFLKNLALMGVSCGTQGKLTVTDDDVIEKSNLSRQFLFRDWNIGQAKSTVAATAAAGINSRLNIDALQNRVGPETENVFDDSFWENLTVVVNALDNVTARLYVDSRCVYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAYLSDPVEYMKAMRTAGDAQARDTLGRVVECLEKEKCNSFQDCITWARLRFEDYFANRVKQLCYTFPEDAATSTGAPFWSAPKRFPRPLQFSSTDLSHINFVMAASILRAETFGIPTPEWAKTRAGLAEAVERVIVPDFEPKKDATIVTDEKATTLSTASVDDAAVIDELNAKLVRCRMSLQPEFRMKAIQFEKDDDTNYHMDMIAGLANMRARNYSVPEVDKLKAKFIAGRIIPAIATSTAMATGFVCLEMYKVLDGSHKVEDYRNTFANLALPLFS
type: DOMAIN
name: ThiF_NAD_FAD-bd
description: THIF-type NAD/FAD binding fold

phrase: HSRQLAVYGRETMRKLFASNVLISGMQGLGVEIAKNIILAGVKSVTLHDENVVELWDLSSNFVFTEEDIGKNRALASVHKLQELNNAVAVSTLTGKLTKEQLSDFQVVVFVDISFEKATEIDDYCHSHQPPIAFIKADVRGLFGSLFCDFGPHFTVLDVDGEEPHSGIIASVSNENPGFVSCVDDERLEFEDGNLVVFSEVEGMTELNDGKPRKIKNVKPFSFTLEEDTSSYGQYMKGGIVTQVKQPKVLNFKPLREALKDPGDFLLSDFSKFDRPPLLHLAFQALDRFSSQAGRFPFAGSEEDAQKLVEIAVDINEGLGDARLEDVNSKLLRHLAFGSRAVLNPMAAMFGGIVGQEVVKACSGKFHPIFQFFYFD
type: DOMAIN
name: ThiF_NAD_FAD-bd
description: THIF-type NAD/FAD binding fold

phrase: WDRWVMRGNPTLRELLDWLKEKGLNAYSISCGSSLLYNSMFSRHKERMNRRVVDLARDVAGVELPAYRRHVDVVVACEDDNDADVDIPL
type: DOMAIN
name: Ub-activating_enz_E1_C
description: Ubiquitin-activating enzyme E1, C-terminal