Protein sequence:
MGDGGEGEDEVQFLRTDDEVVLQCNATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSGMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTTHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSGCEEGYVTGGHVLRLFHGHMDECLTISPADSDDQRRLVYYEGGSVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALIEDQGLVVVDASKAHTKATSFCFRISKEKLDTAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALSLTRCQQEESQAARMIYSTAGLYNHFIKGLDSFSGKPRGSGAPAGTALPLEGVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYEILASLIRGNRANCALFSNNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYSKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVPRLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLNGLFFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRGPHLVGPSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLRKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVESQSRWDRVRIFRAEKSYAVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSELFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEAVPLEHPHYEVSRVDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCTAGATPLAPPGLQPPAEDEARAAEPDPDYENLRRSAGRWGEAEGGKEGTAKEGAPGGTAQAGVEAQPPRAENEKDATTEKNKKRGFLFKAKKAAMMTQPPATPTLPRLPHEVVPADDRDDPDIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLTKVRAVTVTMGDEQGNIHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEMQMLMPVSWSRMPNHFLRVETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQQFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGKRTENGPRRHGLPGVGVTTSLRPPHHFSAPCFVAALPAVGAAEAPARLSPSIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEEEEEEEEEEDEEEKEEDEEEEAREKEDEEKEEEETAEGEKEEYLEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRDRYGILMKAFTMTAAETARRTREFRSPPQEQINMLLHFKDGEDEEDCPLPDEIRQDLLEFHQDLLTHCGIQLEGEEEEPEEEATLGSRLMSLLEKVRLVKKKEEKSEEEPPAEESKAQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLATIEEAIRISEDPARDGPGVRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPTLGKDGALVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEECLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDPELYRMAMPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEEKTEKKKTRKISQSAQTYDAREGYNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVTRGLKDMELDTSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSSGRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLFCKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDIEKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQVSCYRTLCSIYSLGTTRNPYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKSPRERAILGLPNSVEEMCPDIPVLERLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPRWWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQPIVSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEPNPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEINNMSFLTADNKSKMAKSGGSDQERTKKKRLGDRYSVQTSLIVATLKKMLPIGLNMCAPTDQELITLAKTRYALKDTDEEVREFLQNNLHLQGKVEGSPSLRWQMALYRGLPGREEDADDPEKIVRRVQEVSAVLYHLEQMEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENGEAQEEVEVSFEEKEMEKQRLLYQQARLHNRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNADVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMIDCEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGESEKMELFVSFCEDTIFEMQIAAQISEPEGEPEEDEDEGAGLAEAGAEGAEEGAVGPEGAAGTAAAGLTARLAAATSRALRGLSYRSLRRRVRRLRRLTAREAATALAALLWAALAHAGAAGAGAAAGALRLLWGSLFGGGLVEGAKKVTVTELLAGMPDPTGDEVHGEQPAGPGGEADGEGAGEGAGEAWEGAGDEEVAVQEAGPGGADGAVAVAEGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPIIKRKLGVDGEEEELPPEPEPEPEPEPEKADAENGEKEEVPKPPPEPPKKTAPPPPPPKKEEGGSGGLEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDLSGAGSGGGSGWGSGAGEEVEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIYGRERIAELLGMDLATLEITAHNERKPEPPPGLLTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDTTPHRFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS

Annotated regions:
phrase: SIRPNIFVGRAEGTTQYSKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVPRLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLNGLFFPVVSFSAGVKVRFLL
type: DOMAIN
name: SPRY1_RyR
description: Ryanodine receptor, SPRY domain 1

phrase: TWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQ
type: DOMAIN
name: Ion_trans_dom
description: Ion transport domain

phrase: GYVTGGHVLRLFHGHMDECLTISPADSDDQRRLVYYEGGSVCTHARSLWRLEPLRISWSGSHLRWGQPLRIRHVTTGRYLALIEDQGLVVVDASKAHTKATSFCFRISKEKLDTAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAAPDPKALRLGVLKKKAILHQEGHMDDALS
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: YNPQPPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELLKFLQMNGYAVT
type: DOMAIN
name: Ryanodine_rcpt
description: Ryanodine receptor Ryr

phrase: FDPRPVETLNVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKEIYRWPIKESLKAMIAWEWTIE
type: DOMAIN
name: Ryanodine_rcpt
description: Ryanodine receptor Ryr

phrase: YKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNI
type: DOMAIN
name: Ryanodine_rcpt
description: Ryanodine receptor Ryr

phrase: FVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRDDNKRLHPCLVDFHSLPEPERNYNLQMSGETLKTLLALGCHV
type: DOMAIN
name: Ryanodine_rcpt
description: Ryanodine receptor Ryr

phrase: GEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNP
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: DDRDDPDIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLTKVRAVTVTMGDEQGNIHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFEL
type: DOMAIN
name: SPRY3_RyR
description: Ryanodine receptor, SPRY domain 3

phrase: DDEFTQDLFRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVG
type: DOMAIN
name: RIH_assoc-dom
description: RyR/IP3R Homology associated domain

phrase: RIFRAEKSYAVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSELFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGDGFLPVCSLGPGQVGHLNL
type: DOMAIN
name: SPRY2_RyR
description: Ryanodine receptor, SPRY domain 2

phrase: PGGTAQAGVEAQPPRAENEKDATTEKNKKRGFLFKAKKAAMMTQPPATPTLPRLPHEVVPADDRDDPDIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLTKVRAVTVTMGDEQGNIHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQK
type: DOMAIN
name: B30.2/SPRY
description: B30.2/SPRY domain

phrase: HRTLLYGHAILLRHAHSGMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTTHP
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: GSHLRWGQPLRIRHVTTGRYLALIEDQGLVVVDASKAHTKATSFCFRISKEKLDTAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYA
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: GEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNP
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: HRTLLYGHAILLRHAHSGMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTTHP
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: EGYVTGGHVLRLFHGHMDECLTISPADSDDQRRLVYYEGGSVCTHARSLWRLEP
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: HSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPGKRTENGPRRHGLPGVGVTTSLRPPHHFSAPCFVAALPAVGAAEAPARLSPSIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEEEEEEEEEEDEEEKEEDEEEEAREKEDEEKEEEETAEGEKEEYLEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRDRYGILMKAFTMTAAETARRTREFRSPPQEQINMLLHFKDGEDEEDCPLPDEIRQDLLEFHQDLLTHCGIQLEGEEEEPEEEATLGSRLMSLLEKVRLVKKKEEKSEEEPPAEESKAQSLQELVSHTVVRWAQEDFVQSPELVRAMFSLLH
type: DOMAIN
name: RYDR_Jsol
description: Ryanodine receptor, junctional solenoid domain

phrase: SLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYEILASLIRGNRANCALFSNNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTN
type: DOMAIN
name: RIH_dom
description: RIH domain

phrase: GQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPA
type: DOMAIN
name: RIH_dom
description: RIH domain

phrase: MPDPTGDEVHGEQPAGPGGEADGEGAGEGAGEAWEGAGDEEVAVQEAGPGGADGAVAVAEGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPIIKRKLGVDGEEEELPPEPEPEPEPEPEKADAENGEKEEVPKPPPEPPKKTAPPPPPPKKEEGGSGGLEFWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDLSGAGSGGGSGWGSGAGEEVEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKVPLV
type: DOMAIN
name: Ryanrecept_TM4-6
description: Ryanodine Receptor TM 4-6

phrase: GSHLRWGQPLRIRHVTTGRYLALIEDQGLVVVDASKAHTKATSFCFRISKEKLDTAPKRDVEG
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: PARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPPDQEPSQVESQSRWDRVRIFRAEKSYAVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSELFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGDGFLPVCSLGPGQVGHLNLGQDV
type: DOMAIN
name: B30.2/SPRY
description: B30.2/SPRY domain

phrase: EGYVTGGHVLRLFHGHMDECLTISPADSDDQRRLVYYEGGSVCTHARSLWRLEP
type: DOMAIN
name: MIR_motif
description: MIR motif

phrase: YSKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVPRLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLNGLFFPVVSFSAGVKVRFLLGGR
type: DOMAIN
name: SPRY_dom
description: SPRY domain

phrase: TTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLTKVRAVTVTMGDEQGNIHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQ
type: DOMAIN
name: SPRY_dom
description: SPRY domain

phrase: SGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSELFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGDGFLPVCSLGPGQVGHLNLGQD
type: DOMAIN
name: SPRY_dom
description: SPRY domain

phrase: YYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLTKVRAVTVTMGDEQGNIHSSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGK
type: DOMAIN
name: SPRY_dom
description: SPRY domain

phrase: KWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVPRLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLNGLFFPVVSFSAGVKVRFLLG
type: DOMAIN
name: SPRY_dom
description: SPRY domain

phrase: RWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSELFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFRDIEVGDGFLPVCSLGPGQVGHLNLG
type: DOMAIN
name: SPRY_dom
description: SPRY domain

phrase: EVQFLRTDDEVVLQCNATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFVLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSGMYLSCLTTSRSMTDKLAFDVGLQEDATGEACWWTTHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPICSGC
type: DOMAIN
name: Ins145_P3_rcpt
description: Inositol 1,4,5-trisphosphate/ryanodine receptor

phrase: HIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYSKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVPRLVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLNGLFFPVVSFSAGVKVRFLLGGRH
type: DOMAIN
name: B30.2/SPRY
description: B30.2/SPRY domain