Protein sequence:
MLISTLPLLLHEQLAQSTRMRVLCVAEKNSIAKEVAKILSGGRARPRNSLYKYVKNYDFQYTFQGLGPCDVTMTAVAGHVLTTDFGPEYAWGKCPPGRLFDAPFLTKPPPDRDQRAGILKNIIREARNADRLMIWTDCDREGEYIGWEIMSVAQGANPRLNLQTTWRAQFSHLEPQHIVAAANNPKALDMKLVAAVECRTEFDLRVGTLFTRFLTNIYKSKRLVGEKEVVSYGTCQFPTLSFVVDRYVRVRNFRPEPFWSIDLAVTKNGQKVNFSWSRNHLFDRMFVYVIYAQLLEGPQKPRIVGVSTKPTSHYKPLPLTTVDLQKCCSRYFKMLAKAALDAAELLYTAGYISYPRTETDQFPAKLDLKGYITKQTLSLDWGTHATRLLQGSFRPPRGGKHDDKAHPPIYPVKSASLDTLRPDQRKVYEFVVRRFLACCSDDARGLQTKVDLQWRSERFTALGLQVTERNFLDVYPYSDWKSLAQLPEFAEGEEVTPSSCKVKEGKTSPPNYMTEAELIALMDANGIGTDATIADHVEKIAQRNYVTRRKIGKSEVFIPTSLGISLIDAFDAILIDRISLLKPFLRRAMEGFLQKISRGEITKQDVISQLLPLYKEAFMESNQKGHVISDTFIQTSRGLS

Annotated regions:
phrase: TTWRAQFSHLEPQHIVAAANNPKALDMKLVAAVECRTEFDLRVGTLFTRFLTNIYKSKRLVGEKEVVSYGTCQFPTLSFVVDRYVRVRNFRPEPFW
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: STKPTSHYKPLPLTTVDLQKCCSRYFKMLAKAALDAAELLYTAGYISYPRTETDQFPAKLDLKGYITKQTLSLDWGTHATRLLQGSFRPPRGGKHDDKAHPPIYPVKSASLDTLRPDQRKVYEFVVRRFLACCSDDARGLQTKVDLQWRSERFTALGLQVTERNFLDVYPYSDWKSLAQLPEFAEGEEVTPSSCKVKEGKTSPPNYMTEAELIALMDANGIGTDATIADHVEKIAQRNYVTRRKIGKSEVFIPTSLGISL
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: MKLVAAVECRTEFDLRVGTLFTRFLTNIYKSKRLVGEKEVVSYGTCQFPTLSFVVDRYVRVRNFRPEPFWSIDLAVTKNGQKVNFSWSRNHLFDRMFVYVIYAQLLEGPQKPRIVGVSTKPTSHYKPLPLTTVDLQKCCSRYFKMLAKAALDAAELLYTAGYISYPRTETDQFPAKLDLKGYITKQTLSLDWGTHATRLLQGSFRPPRGGKHDDKAHPPIYPVKSASLDTLRPDQRKVYEFVVRRFLACCSDDARGLQTKVDLQWRSERFTALGLQVTERNFLDVYPYSDWKSLAQLPEFAEGEEVTPSSCKVKEGKTSPPNYMTEAELIALMDANGIGTDATIADHVEKIAQRNYVTRRKIGKSEVFIPTSLGISLIDAFDAILIDRISLLKPFLRRAMEGFLQKISRGEITKQDVISQLLPLYKEA
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LMIWTDCDREGEY
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: VSYGTCQFPTLSFVVDRY
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: AGYISYPRT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: VYEFVVRRFLACCSDD
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GIGTDATIADHVEK
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: RVLCVAEKNSIAKEVAKILSGGRARPRNSLYKYVKNYDFQYTFQGLGPCDVTMTAVAGHVLTTDFGPEYAWGKCPPGRLFDAPFLTKPPPDRDQRAGILKNIIREARNADRLMIWTDCDREGEYIGWEIMSVAQGANPRLNLQTTWRAQFSHLE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: ELLYTAGYISYPRT
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site

phrase: VLCVAEKNSIAKEVAKILSGGRARPRNSLYKYVKNYDFQYTFQGLGPCDVTMTAVAGHVLTTDFGPEYAWGKCPPGRLFDAPFLTKPPPDRDQRAGILKNIIREARNADRLMIWTDCDREGEYIGWEIMSVAQGAN
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: RVLCVAEKNSIAKEVAKILSGGRARPRNSLYKYVKNYDFQYTFQGLGPCDVTMTAVAGHVLTTDFGPEYAWGKCPPGRLFDAPFLTKPPPDRDQRAGILKNIIREARNADRLMIWTDCDREGEYIGWEIMSVAQGAN
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: RVLCVAEKNSIAKEVAKILSGGRARPRNSLYKYVKNYDFQYTFQGLGPCDVTMTAVAGHVLTTDFGPEYAWGKCPPGRLFDAPFLTKPPPDRDQRAGILKNIIREARNADRLMIWTDCDREGEYIGWEIMSVAQGANPRLNLQTTWRAQFSHLEPQHIVAAANN
type: DOMAIN
name: TOPRIM_TopoIII
description: DNA topoisomerase 3-like, TOPRIM domain

phrase: LDMKLVAAVECRTEFDLRVGTLFTRFLTNIYKSKRLVGEKEVVSYGTCQFPTLSFVVDRYVRVRNFRPEPFWSIDLAVTKNGQKVNFSWSRNHLFDRMFVYVIYAQLLEGPQKPRIVGVSTKPTSHYKPLPLTTVDLQKCCSRYFKMLAKAALDAAELLYTAGYISYPRTETDQFPAKLDLKGYITKQTLSLDWGTHATRLLQGSFRPPRGGKHDDKAHPPIYPVKSASLDTLRPDQRKVYEFVVRRFLACCSDDARGLQTKVDLQWRSERFTALGLQVTERNFLDVYPYSDWKSLAQLPEFAEGEEVTPSSCKVKEGKTSPPNYMTEAELIALMDANGIGTDATIADHVEKIAQRNYVTRRKIGKSEVFIPTSLGISLIDAFDAILIDRISLLKPFLRRAMEGFLQKISRGEITKQDV
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central