Protein sequence:
MADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEMEKIEIKDEPAGEDCEICGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSNCDYKEAAQK

Annotated regions:
phrase: IEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKV
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: DNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: VFLASDPDREGEA
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LSAGRVQSVALRLVIDRE
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: IGLITYMRT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LYKLIWERFVASQMAP
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: KIGRPSTYAPTIDT
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: DNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELED
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: KENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYW
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: NLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNEITKDAVKESFKN
type: DOMAIN
name: TOPRIM_TopoI
description: DNA topoisomerase 1, TOPRIM domain

phrase: TKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIV
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: LVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQMGVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILELEDSKENRVVFNE
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: GRDCPKCNQYLVENKKGKTTQVICSNCDYKEAA
type: DOMAIN
name: Topo_IA_Znf
description: DNA topoisomerase, type IA, zn finger

phrase: GEDCEICGSPMVIKMGRYGKFMACSNFPDCRNTKAIV
type: DOMAIN
name: Topo_IA_Znf
description: DNA topoisomerase, type IA, zn finger

phrase: GVKCPKCNDGDVVERKSKKNRVFYGCSKYPECDFISWDK
type: DOMAIN
name: Topo_IA_Znf
description: DNA topoisomerase, type IA, zn finger

phrase: MNLVDAQQARRILDRLVGYNISPVLWKKVKKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPFKLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKTMMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKVEAKQYITDKYGESYTSKRKASGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVSLDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPAQHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEIVHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQD
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: QQLYEGIDLKKQGTIGLITYMRT
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site