Protein sequence:
MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGADDYVTWCIGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLIPRKDVHKQLTIVEKLIHQADILINAGDPDREGQLLVDEVFSYANLSVDKLNQIQRCLISDLNPSAVEKAVNKLQSNRNFIPLATSALARARADWLYGINMTRAYTLRGRQAGYQGVLSVGRVQTPVLGLIVRRDLEIENFKPQDFFEVLAHIQAETPEKITALSAQEKANIPQFKALWQPSKACEDYQDEEGRVLSLGLVENVVKRIAQQPAEVVEYVDKREHESAPLPYSLSALQIDAAKRYGLSAQEVLDICQRLYETHRLITYPRSDCRYLPEEHFGERTKVFQAISRHISDYQPLPDILNPEQKNRCWNDKKVEAHHAIIPTAKNTPVNLNQREWQIYHLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQVAGWKQLLGKEDSDEQQEPLLPVVKKGQILFCEKGEIVSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLYKKGRNIHSTETGRILIQALPDVATQPDMTAHWESQLTSISQKEMSYQQFMSTLTNFLPELMRYVNFAALRQLSQVEKPQSFSKKMSAKSKKRPT

Annotated regions:
phrase: QIQRCLISDLNPSAVEKAVNKLQSNRNFIPLATSALARARADWLYGINMTRAYTLRGRQAGYQGVLSVGRVQTPVLGLIVRRDLEIENFKPQDFF
type: DOMAIN
name: Topo_IA_2
description: DNA topoisomerase, type IA, domain 2

phrase: MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGADDYVTWCIGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLIPRKDVHKQLTIVEKLIHQADILINAGDPDREGQLLVDEVFSYANLSVDKLNQIQRCLISDLNPSAVEKAVNK
type: DOMAIN
name: TOPRIM_TopoIII
description: DNA topoisomerase 3-like, TOPRIM domain

phrase: QRLYETHRLITYPRS
type: ACTIVE_SITE
name: Topo_IA_AS
description: DNA topoisomerase, type IA, active site

phrase: MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGADDYVTWCIGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLIPRKDVHKQLTIVEKLIHQADILINAGDPDREGQLLVDEVFSYANLSV
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: MRLFIAEKPSLARAIADVLPKPHQRGDGFIKCGADDYVTWCIGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLIPRKDVHKQLTIVEKLIHQADILINAGDPDREGQLLVDEVFSYANLSVDKLNQIQRCL
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: VDKREHESAPLPYSLSALQIDAAKRYGLSAQEVLDICQRLYETHRLITYPRSDCRYLPEEHFGERTKVFQAISRHISDYQPLPDILNPEQKNRCWNDKKVEAHHAIIPTAKNTPVNLNQREWQIYHLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQVAGWKQLLGKEDSDEQQEPLLPVVKKGQILFCEKGEIVSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLYKKGRNIHSTETGRIL
type: DOMAIN
name: Topo_IA_DNA-bd_dom
description: DNA topoisomerase, type IA, DNA-binding domain

phrase: PLATSALARARADWLYGINMTRAYTLRGRQAGYQGVLSVGRVQTPVLGLIVRRDLEIENFKPQDFFEVLAHIQAETPEKITALSAQEKANIPQFKALWQPSKACEDYQDEEGRVLSLGLVENVVKRIAQQPAEVVEYVDKREHESAPLPYSLSALQIDAAKRYGLSAQEVLDICQRLYETHRLITYPRSDCRYLPEEHFGERTKVFQAISRHISDYQPLPDILNPEQKNRCWNDKKVEAHHAIIPTAKNTPVNLNQREWQIYHLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQVAGWKQLLGKEDSDEQQEPLLPVVKKGQILFCEKGEIVSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLYKKGRNIHSTETGRILIQALPDVATQPDMTAHWESQLTSISQKEMSYQQF
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LINAGDPDREGQL
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LSVGRVQTPVLGLIVRRD
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: HRLITYPRS
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: IYHLIARQYLMQFCPD
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: GLGTEATRAGIIEL
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central

phrase: LFIAEKPSLARAIADVLPKPHQRGDGFIKCGADDYVTWCIGHLLEQAEPDAYDPKFKQWRLEHLPIIPEKWQLIPRKDVHKQLTIVEKLIHQADILINAGDPDREGQLLVDEVFSYANLSVDKLNQIQRCLI
type: DOMAIN
name: TOPRIM_dom
description: TOPRIM domain

phrase: IPLATSALARARADWLYGINMTRAYTLRGRQAGYQGVLSVGRVQTPVLGLIVRRDLEIENFKPQDFFEVLAHIQAETPEKITALSAQEKANIPQFKALWQPSKACEDYQDEEGRVLSLGLVENVVKRIAQQPAEVVEYVDKREHESAPLPYSLSALQIDAAKRYGLSAQEVLDICQRLYETHRLITYPRSDCRYLPEEHFGERTKVFQAISRHISDYQPLPDILNPEQKNRCWNDKKVEAHHAIIPTAKNTPVNLNQREWQIYHLIARQYLMQFCPDAEYRKSKITLNIAGGTFIAQARNLQVAGWKQLLGKEDSDEQQEPLLPVVKKGQILFCEKGEIVSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLYKKGRNIHSTETGRILIQALPDVATQPDMTAHWESQLTSISQKEMSYQQFMSTLTNFLPEL
type: DOMAIN
name: Topo_IA_cen
description: DNA topoisomerase, type IA, central