nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
MPQTVNPAPQDAALEEEARAMIGRLVERALSDAEITPEEVLPVAALPVETLVDAAEEVSRKHASRTFNICAIVNAKSGKCPENCRWCSQSASWPDAKSPVYGLIDAEEALKSAKAAYESGASRFSLVMSGRKLSRREVRETAEIVRRLREAFPMEVCISPGLLTEDEFRELRDAGVARAHCNLEAAPSFFPEVCTSHSFEAKIETLEAARRAGLQICSGGIIGMGEDRLARIELALALRKLRVPSLPLNVLEPIPGTPLGSMPRISEEEVIRTAAVWRLLNPTVELRFAGGRRRLSDACLHACFRAGVNSAIAGDMLTTPGTDHNHELSLVREAGYKLEADEGLAVDRDHIWHPYAGTILTPRVEKVVGAEGVKLKLADGRELIDGTSAWWCAPFGYKPKALVDAVQRQAAELPHVMFGGLTHDPAIGLAKRLTEILPAALQRIFFADSGSVAVEAAMKLAIQYQMASGRPDRTGFVTIEGGYHGDTWNAMSVCDPVAGMHGAFGGALPQRHFVPAPKSVFGGDWDPADIEPLRAFLEAHDDVAAFILEPILQGASAMRFYHPQFLAEAAKLCREHDVLLILDEIATGFGRTGRDFACQWADVTPDVMTIGKALTGGMVTLSAVAVQNRVADRVSAHPPFAFMHGPTFMANPIACAAACAAMDLYRSDDWPAKARALGERLEKGLAHLRGRPGIRDVRVLGAVAVVETEVPGKIPVLQLRFVKEGVWVRPIGRLWYLMPPFVMTEAETEALLKGFLTVLERHLEENPV

Annotated regions:
phrase: GKCPENCRWCSQSASWPDAKSPVYGLIDAEEALKSAKAAYESGASRFSLVMSGRKLSRREVRETAEIVRRLREAFPMEVCISPGLLTEDEFRELRDAGVARAHCNLEAAPSFFPEVCTSHSFEAKIETLEAARRAGLQICSGGIIGMGE
type: DOMAIN
name: rSAM
description: Radical SAM

phrase: RTFNICAIVNAKSGKCPENCRWCSQSASWPDAKSPVYGLIDAEEALKSAKAAYESGASRFSLVMSGRKLSRREVRETAEIVRRLREAFPMEVCISPGLLTEDEFRELRDAGVARAHCNLEAAPSFFPEVCTSHSFEAKIETLEAARRAGLQICSGGIIGMGEDRLARIELALALRKLRVPSLPLNVLEPIPGTPLGSMPRISEEEVIRTAAVWRLLNPTVELRF
type: DOMAIN
name: rSAM
description: Radical SAM

phrase: PLNVLEPIPGTPLGSMPRISEEEVIRTAAVWRLLNPTVELRFAGGRRRLSDACLHACFRAGVNSAIAGDMLTTPGTDHNHELSLVREAGY
type: DOMAIN
name: BATS_dom
description: Biotin and thiamin synthesis-associated domain

phrase: LILDEIATGFGRTGRDFACQWADVTPDVMTIGKALTG
type: CONSERVED_SITE
name: Aminotrans_3_PPA_site
description: Aminotransferases class-III pyridoxal-phosphate attachment site

phrase: PLNVLEPIPGTPLGSMPRISEEEVIRTAAVWRLLNPTVELRFAGGRRRLSDACLHACFRAGVNSAIAGDMLTTPGTDHNHELSLVREAGYK
type: DOMAIN
name: BATS_dom
description: Biotin and thiamin synthesis-associated domain

phrase: CAIVNAKSGKCPENCRWCSQSASWPDAKSPVYGLIDAEEALKSAKAAYESGASRFSLVMSGRKLSRREVRETAEIVRRLREAFPMEVCISPGLLTEDEFRELRDAGVARAHCNLEAAPSFFPEVCTSHSFEAKIETLEAARRAGLQICSGGIIGMGEDRLARIELALALRKLRVPSLPLNVLEPIPGTPLGSMPRISEEEVIRTAAVWRLLN
type: DOMAIN
name: Elp3/MiaA/NifB-like_rSAM
description: Elp3/MiaA/NifB-like, radical SAM core domain
Protein sequence:
MKRIEAYTDGACSGNPGPGGWGAILRWNDNVKELKGGEADTTNNRMELMAAISALSALKEPCEVDLYTDSVYVRDGISGWIEGWKRNGWKTAAKKPVKNAELWQALDEARKPHKVNWHWVKGHAGHPENERADELAREGMEPFKYGGRKSLKVQ

Annotated regions:
phrase: KRIEAYTDGACSGNPGPGGWGAILRWNDNVKELKGGEADTTNNRMELMAAISALSALKEPCEVDLYTDSVYVRDGISGWIEGWKRNGWKTAAKKPVKNAELWQALDEARKPHKVNWHWVKGHAGHPENERADELAREG
type: DOMAIN
name: RNaseH_domain
description: Ribonuclease H domain

phrase: MKRIEAYTDGACSGNPGPGGWGAILRWNDNVKELKGGEADTTNNRMELMAAISALSALKEPCEVDLYTDSVYVRDGISGWIEGWKRNGWKTAAKKPVKNAELWQALDEARKPHKVNWHWVKGHAGHPENERADELAREGM
type: DOMAIN
name: RNaseH_domain
description: Ribonuclease H domain
Protein sequence:
MGAHHPALGLLLLLLCPAQVFSQSCVWYGECGIATGDKRYNCKYSGPPKPLPKDGYDLVQELCPGLFFDNVSLCCDIQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQENKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPPPMPWRIWGLDAMYVIMWVTYVAFLFVFFGALLAVWCHRRRYFVSEYTPIDSNIAFSVNSSDKGEASCCDPLGAAFDDCLRRMFTKWGAFCVRNPTCIIFFSLAFITVCSSGLVFVQVTTNPVELWSAPHSQARLEKEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVKNYKNPNLTISFTAERSIEDELNRESNSDVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCVRGADDGQGSHASESYLFRFFKNYFAPLLLKDWLRPIVVAVFVGVLSFSVAVVNKVDIGLDQSLSMPNDSYVIDYFKSLAQYLHSGPPVYFVLEEGYNYSSRKGQNMVCGGMGCDNDSLVQQIFNAAELDTYTRVGFAPSSWIDDYFDWVSPQSSCCRLYNVTHQFCNASVMDPTCVRCRPLTPEGKQRPQGKEFMKFLPMFLSDNPNPKCGKGGHAAYGSAVNIVGDDTYIGATYFMTYHTILKTSADYTDAMKKARLIASNITETMRSKGSDYRVFPYSVFYVFYEQYLTIIDDTIFNLSVSLGSIFLVTLVVLGCELWSAVIMCITIAMILVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTMSTKGSRVSRAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFEIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKAKRHTTYERYRGTERERLLNF

Annotated regions:
phrase: VDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLGLDIKRQEKNHLDILCCV
type: DOMAIN
name: HMGCR/SNAP/NPC1-like_SSD
description: HMGCR/SNAP/NPC1-like, sterol-sensing domain

phrase: DVFTVIISYVVMFLYISLALGHIQSCSRLLVDSKISLGIAGILIVLSSVACSLGIFSYMGMPLTLIVIEVIPFLVLAVGVDNIFILVQTYQRDERLQEETLDQQLGRILGEVAPTMFLSSFSETSAFFFGALSSMPAVHTFSLFAGMAVLIDFLLQITCFVSLLG
type: DOMAIN
name: SSD
description: Sterol-sensing domain

phrase: KEYFDKHFGPFFRTEQLIIQAPNTSVHIYEPYPAGADVPFGPPLNKEILHQVLDLQIAIESITASYNNETVTLQDICVAPLSPYNKNCTIMSVLNYFQNSHAVLDSQVGDDFYIYADYHTHFLYCVRAPASLNDTSLLHGPCLGTFGGPVFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTERLQRAWAWEKEFISFVKNYKNPNLTISFTAE
type: DOMAIN
name: NPC1_MLD
description: NPC1, middle luminal domain

phrase: QSCVWYGECGIATGDKRYNCKYSGPPKPLPKDGYDLVQELCPGLFFDNVSLCCDIQQLQTLKSNLQLPLQFLSRCPSCFYNLMTLFCELTCSPHQSQFLNVTATEDYFDPKTQENKTNVKELEYFVGQSFANAMYNACRDVEAPSSNEKALGLLCGRDARACNATNWIEYMFNKDNGQAPFTIIPVFSDLSILGMEPMRNATKGCNESVDEVTGPCSCQDCSIVCGPKPQPPPPPMPWRIWGL
type: DOMAIN
name: NPC1_N
description: Niemann-Pick C1, N-terminal
Protein sequence:
MDSVFSNVARAPEDPILGVTVAYNNDPSPVKINLGVGAYRTEEGKPLVLDVVRKAEQQLVNDPSRVKEYIPIVGISDFNKLSAKLILGADSPAITESRVTTVQCLSGTGSLRVGAEFLKTHYHQSVIYIPKPTWGNHPKVFNLAGLSVEYFRYYDPATRGLDFKGLLEDLGAAPSGAIVLLHACAHNPTGVDPTSEQWEQIRQLMRSKSLLPFFDSAYQGFASGSLDTDAQSVRTFVADGGECLIAQSYAKNMGLYGERVGALSIVCKSADVASKVESQVKLVVRPMYSSPPIHGASIVATILKSSDMYNNWTIELKEMADRIKSMRQQLFEAIQARGTPGDWSHIIKQIGMFTFTGLNKEQVEFMTKEFHIYMTSDGRISMAGLSSKTVPHLADAMHAAVTRLG

Annotated regions:
phrase: KINLGVGAYRTEEGKPLVLDVVRKAEQQLVNDPSRVKEYIPIVGISDFNKLSAKLILGADSPAITESRVTTVQCLSGTGSLRVGAEFLKTHYHQSVIYIPKPTWGNHPKVFNLAGLSVEYFRYYDPATRGLDFKGLLEDLGAAPSGAIVLLHACAHNPTGVDPTSEQWEQIRQLMRSKSLLPFFDSAYQGFASGSLDTDAQSVRTFVADGGECLIAQSYAKNMGLYGERVGALSIVCKSADVASKVESQVKLVVRPMYSSPPIHGASIVATILKSSDMYNNWTIELKEMADRIKSMRQQLFEAIQARGTPGDWSHIIKQIGMFTFTGLNKEQVEFMTKEFHIYMTSDGRISMAGLSSKTVPHLAD
type: DOMAIN
name: Aminotransferase_I/II_large
description: Aminotransferase, class I/classII, large domain

phrase: SYAKNMGLYGERV
type: BINDING_SITE
name: NHTrfase_class1_PyrdxlP-BS
description: Aminotransferases, class-I, pyridoxal-phosphate-binding site
Protein sequence:
MTINIYNTLTRKKEEFVPLEPGKVKMYVCGPTVYNYIHIGNARPAIVYDTVRKYLEYSGYDVNFVSNFTDVDDKLIKAANELGEDVPTIADRFIQAYFEDVSALGCKKADLHPRVTENMDDIIAFIETLIEKGYAYEADGDVYYSTRSFEGYGKLSHQSIDELKTGARIRVGEKKRDALDFALWKAAKNQEISWDSPWGEGRPGWHIECSAMVKKYLGDTIDIHAGGQDLTFPHHENEIAQSEALTGKPFAKYWMHNGYINIENEKMSKSLGNFVLVHDIVKEQDPDVLRFFMLSVHYRHPINYSMDLLESTKSAFNRLKTSYANLHHRLESSTNITEDNAKWLAKVEEQRATFISEMNDDFNTANAISVLFELAKQANYYMENDHTSEEVIKAFIGLFQEITSVLGFSLEEKHTLEKEVEALIEQRNEARRNRDFALSDQIRDQLKSMNIVLEDTPQGTRWKRGE

Annotated regions:
phrase: NIYNTLTRKKEEFVPLEPGKVKMYVCGPTVYNYIHIGNARPAIVYDTVRKYLEYSGYDVNFVSNFTDVDDKLIKAANELGEDVPTIADRFIQAYFEDVSALGCKKADLHPRVTENMDDIIAFIETLIEKGYAYEADGDVYYSTRSFEGYGKLSHQSIDELKTGARIRVGEKKRDALDFALWKAAKNQEISWDSPWGEGRPGWHIECSAMVKKYLGDTIDIHAGGQDLTFPHHENEIAQSEALTGKPFAKYWMHNGYINIENEKMSKSLGNFVLVHDIVKEQDPDVLRFFMLSVHYRHPINY
type: DOMAIN
name: tRNA-synt_1_cat_dom
description: tRNA synthetases class I, catalytic domain

phrase: TFISEMNDDFNTANAISVLFELAKQANYYMENDHTSEEVIKAFIGLFQEITSVLGFSLEEKHTL
type: DOMAIN
name: Cys-tRNA-synt_Ia_DALR
description: Cysteinyl-tRNA synthetase, class Ia, DALR

phrase: FVPLEPGKVKMYVCGPTVYNYIHIGNARPAIVYDTVRKYLEYSGYDVNFVSNFTDVDDKLIKAANELGEDVPTIADRFIQAYFEDVSALGCKKADLHPRVTENMDDIIAFIETLIEKGYAYEADGDVYYSTRSFEGYGKLSHQSIDELKTGARIRVGEKKRDALDFALWKAAKNQEISWDSPWGEGRPGWHIECSAMVKKYLGDTIDIHAGGQDLTFPHHENEIAQSEALTGKPFAKYWMHNGYINIENEKMSKSLGNFVLVHDIVKEQDPDVLRFFMLSVHYRHPINYSMDLLEST
type: DOMAIN
name: tRNA-synt_1_cat_dom
description: tRNA synthetases class I, catalytic domain

phrase: LEKEVEALIEQRNEARRNRDFALSDQIRDQLKSMNIVLEDTPQGTR
type: DOMAIN
name: CysS_C
description: Cysteinyl-tRNA ligase, anticodon binding domain

phrase: FISEMNDDFNTANAISVLFELAKQANYYMENDHTSEEVIKAFIGLFQEITSVLGFS
type: DOMAIN
name: Cys-tRNA-synt_Ia_DALR
description: Cysteinyl-tRNA synthetase, class Ia, DALR
Protein sequence:
MRAERLRLSEEQGQRILRLYHLYRLTIGLVLVLLISSELEDQVLKLVHPELFHVGSWCYLVFNILVALFLPPSRQLLPIFILALTDVLMLCGLFYAGGGVPSGIGSLLVVAVAIANILLRGRIGLVIAAAASLGLLYLTFFLSLSSPDATNHYVQAGGLGTLCFAAALVIQALVRRQEQTETLAEERAETVANLEELNALILQRMRTGILVVDSRQAILLANQAALGLLRQDDVQGASLGRHSPMLMHCMKQWRLNPSLRPPTLKVVPDGPTVQPSFISLNREDDQHVLIFLEDISQIAQQAQQMKLAGLGRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQRFVDEYPGRLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAHGRGQVWLSLARDPESDLPVLEVIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITFAHPRKLS

Annotated regions:
phrase: DPHQLNQVLSNLVQNGLRYSAQAHGRGQVWLSLARDPESDLPVLEVIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITF
type: DOMAIN
name: HATPase_dom
description: Histidine kinase/HSP90-like ATPase domain

phrase: LGRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLS
type: DOMAIN
name: HisK_dim/P_dom
description: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

phrase: PVLEVIDDGPGVPA
type: DOMAIN
name: Sig_transdc_His_kin-like_C
description: Signal transduction histidine kinase-related protein, C-terminal

phrase: NLFEPFFTTE
type: DOMAIN
name: Sig_transdc_His_kin-like_C
description: Signal transduction histidine kinase-related protein, C-terminal

phrase: KGTGLGLYLSRELCESNQ
type: DOMAIN
name: Sig_transdc_His_kin-like_C
description: Signal transduction histidine kinase-related protein, C-terminal

phrase: GIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQAEPQQLDLKEWLQRFVDEYPGRLRNDSQLHLQLGAGDIQTRMDPHQLNQVLSNLVQNGLRYSAQAHGRGQVWLSLARDPESDLPVLEVIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITFAHP
type: DOMAIN
name: His_kinase_dom
description: Histidine kinase domain

phrase: GLGRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRRQ
type: DOMAIN
name: HisK_dim/P_dom
description: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

phrase: MDPHQLNQVLSNLVQNGLRYSAQAHGRGQVWLSLARDPESDLPVLEVIDDGPGVPADKLNNLFEPFFTTESKGTGLGLYLSRELCESNQARIDYRNREEGGGCFRITFAHP
type: DOMAIN
name: HATPase_dom
description: Histidine kinase/HSP90-like ATPase domain

phrase: GRLTAGIAHEIRNPLGAISHAAQLLQESEELDAPDRRLTQIIQDQSKRMNLVIENVLQLSRRR
type: DOMAIN
name: HisK_dim/P_dom
description: Signal transduction histidine kinase, dimerisation/phosphoacceptor domain

phrase: ELNALILQRMRTGILVVDSRQAILLANQAALGLLRQDDVQGASLGRHSPMLMHCMKQWRLNPSL
type: DOMAIN
name: PAS
description: PAS domain
Protein sequence:
MVFGTGIDIIKIERVARLIEKEAFMKKFFTDREREYLKHKRAESAAGYFSAKEAIVKSMGTGFTGFKFKDVEVLREDNEPFVILHGNARKIAEDMGIGTIKVSISHEKDFAISSAIALKEVKGRGKEYLLKEYPLNILRKRENNSHKGTYGKVSIIGGSYTMSGAAILAANAALRTGSGLVNCVIPECIIERVASSVYEATYTPLNHSGGTINLTQKDINLILEKSDALSIGTGIGFEEKFLKPIEEILKLSRIPIVIDADAINILALDVNILKKERECSVILTPHPLEMSRLTGLSVNYINSNREEVAKKFAKEHNCILLLKGHETVVSNGDKVYINKSGNPGMATGGSGDVLTGIICSLLGQGYTAYESGVLGSYIHGLAGDMAYEVYGYGLKASDITNYIGQYVK

Annotated regions:
phrase: LKEYPLNILRKRENNSHKGTYGKVSIIGGSYTMSGAAILAANAALRTGSGLVNCVIPECIIERVASSVYEATYTPLNHSGGTINLTQKDINLILEKSDALSIGTGIGFEEKFLKPIEEILKLSRIPIVIDADAINILALDVNILKKERECSVILTPHPLEMSRLTGLSVNYINSNREEVAKKFAKEHNCILLLKGHETVVSNGDKVYINKSGNPGMATGGSGDVLTGIICSLLGQGYTAYESGVLGSYIHGLAGDMAYEVYGYGLKASDITNYIGQYV
type: DOMAIN
name: CARKD
description: ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase

phrase: LKEYPLNILRKRENNSHKGTYGKVSIIGGSYTMSGAAILAANAALRTGSGLVNCVIPECIIERVASSVYEATYTPLNHSGGTINLTQKDINLILEKSDALSIGTGIGFEEKFLKPIEEILKLSRIPIVIDADAINILALDVNILKKERECSVILTPHPLEMSRLTGLSVNYINSNREEVAKKFAKEHNCILLLKGHETVVSNGDKVYINKSGNPGMATGGSGDVLTGIICSLLGQGYTAYESGVLGSYIHGLAGDMAYEVYGYGLKASDITNYIGQYV
type: DOMAIN
name: CARKD
description: ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase

phrase: YLLKEYPLNILRKRENNSHKGTYGKVSIIGGSYTMSGAAILAANAALRTGSGLVNCVIPECIIERVASSVYEATYTPLNHSGGTINLTQKDINLILEKSDALSIGTGIGFEEKFLKPIEEILKLSRIPIVIDADAINILALDVNILKKERECSVILTPHPLEMSRLTGLSVNYINSNREEVAKKFAKEHNCILLLKGHETVVSNGDKVYINKSGNPGMATGGSGDVLTGIICSLLGQGYTAYESGVLGSYIHGLAGDMAYEVYGYGLKASDITNYIGQY
type: DOMAIN
name: CARKD
description: ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase

phrase: GGSGDVLTGI
type: CONSERVED_SITE
name: Carbohydrate_kinase_pred_CS
description: Carbohydrate kinase, predicted, conserved site

phrase: TGIDIIKIERVARLIEKEAFMKKFFTDREREYLKHKRAESAAGYFSAKEAIVKSMGTGFTGFKFKDVEVLREDNEPFVILHGNARKI
type: DOMAIN
name: 4-PPantetheinyl_Trfase_dom
description: 4'-phosphopantetheinyl transferase domain

phrase: FGTGIDIIKIERVARLIEKEAFMKKFFTDREREYLKHKRAESAAGYFSAKEAIVKSMGTGFTGFKFKDVEVLREDNEPFVILHGNARKIAEDMGIGTIKVSISHEKDFAISSA
type: DOMAIN
name: Ppantetheine-prot_Trfase_dom
description: Phosphopantetheine-protein transferase domain

phrase: NSHKGTYGKVSIIGGSYTMSGAAILAANAALRTGSGLVNCVIPECIIERVASSVYEATYTPLNHSGGTINLTQKDINLILEKSDALSIGTGIGFEEKFLKPIEEILKLSRIPIVIDADAINILALDVNILKKERECSVILTPHPLEMSRLTGLSVNYINSNREEVAKKFAKEHNCILLLKGHETVVSNGDKVYINKSGNPGMATGGSGDVLTGIICSLLGQGYTAYESGVLGSYIHGLAGDMAYEVYGYGLKASDITNY
type: DOMAIN
name: CARKD
description: ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase

phrase: VSIIGGSYTMSGAAILAANAALRTGSGLVNCVIPECIIERVASSVYEATYTPLNHSGGTINLTQKDINLILEKSDALSIGTGIGFEEKFLKPIEEILKLSRIPIVIDADAINILALDVNILKKERECSVILTPHPLEMSRLTGLSVNYINSNREEVAKKFAKEHNCILLLKGHETVVSNGDKVYINKSGNPGMATGGSGDVLTGIICSLLGQGYTAYESGVLGSYIHGLAGDMAYEVYGYGLKASDITNY
type: DOMAIN
name: CARKD
description: ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase
Protein sequence:
MKRRTPPDSPLLFDTVPLVPDFKLELKARKAGHWPVAGADEAGRGPLAGPVVAAAVILDPKRIPEGLNDSKQLSAQRREELFVQILATATVSIASSSSTRIDETDIRKASLDAMRRAICSLAIPASYVLTDGLDVPPGLDCPGQAVVKGDARSVSIAAASIVAKVTRDRMMARAHNVFPDYGFAAHAGYGTAQHRAGIEKHGPCSLHRMSFRPLRKGEDGPEMDELIPE

Annotated regions:
phrase: WPVAGADEAGRGPLAGPVVAAAVILDPKRIPEGLNDSKQLSAQRREELFVQILATATVSIASSSSTRIDETDIRKASLDAMRRAICSLAIPASYVLTDGLDVPPGLDCPGQAVVKGDARSVSIAAASIVAKVTRDRMMARAHNVFPDYGFAAHAGYGTAQHRAGIEKHGPCSLHRMSFRPLRKGEDGPE
type: DOMAIN
name: RNase_HII/HIII_dom
description: Ribonuclease HII/HIII domain

phrase: AGADEAGRGPLAGPVVAAAVILDPKRIPEGLNDSKQLSAQRREELFVQILATATVSIASSSSTRIDETDIRKASLDAMRRAICSLAIPASYVLTDGLDVPPGLDCPGQAVVKGDARSVSIAAASIVAKVTRDRMMARAHNVFPDYGFAAHAGYGTAQHRAGIEKHGPCSLHRMSF
type: DOMAIN
name: RNase_HII/HIII_dom
description: Ribonuclease HII/HIII domain
Protein sequence:
MIDNILQFFLKNVPQDKTYEINNLQDANHLIIRNTRTGTRRLFEYVNNFQQFLNTIRNNFNGPCAKHDMGASCEDTEEPAEKHAAQTLDGHDWVLESNDFCIFVKPFILKKHYDIIQKYINFEDFFKSTDPGYINKCVQAGDYYYWPNWPKKQAFSFNGWQLFLNIKFGIVIEPTIPIIHNKKLGPVDLFVFDPKCFLNVELSLRTNHDPPQTLFVNGKTKFDDSHEDLFILKMADGTVATCKVNGELVNSDKNFFNYIRDDINLEECITVPKYKHIVNVNLKSLRVFENNNFDKNDVDLSDTRSRKPRIVPIISASSENADYIQTQINLGLIAIHENMVKVLATHERANDPNLLQQYFEKSKFKNFDFLIYVLWKILTKNENFSYRETDIKLFLELLCESLFACDKEALNEALKRCEPYKKQEKIVFNRACNHWFDFDDTKLCVSLGYYFGIHYMIYLTQSAKNEILDHDELWAYTYENVMALNLPPDIVCKGFFRKLENVVTGVNLVFNGKHYQIVKKEDDLFKLTKSNCYKLSNIKFNNWKYLYLTTHGVYNVFTNSFHSSCPFLLGTTLPQTFKKPTDEKYLPEDAFNYMLSTSADELSIYRTYHIAKMCRDVKMLKTNTAIVNYMGNCNTCQADMRVALNNLFRDLWNLDDENLITLALYVNKNRVSDMLHNLKCKPCRSTVSGSRPKCKCYKKIKINRKALKVCLMADMFGNDAELSELIWMLIFTNKTYVSTTLIRTNSEFVNQHGEFFSKEHNKIIQYLYRTIHKIEYVDMLMDKFNDKRLFLTELRDDVAREPDVQFEESDNISKFYTHHADALMILKKYNVWWDKIILARSTDDLPTWLTRFYMRIIMSKVDLKEYSYNYLKKIVEGYLYFKRFTNFNHANAIMLMHFAASLAIPVDYGKKAIYMPGEPGSGKSSFFELLDYLVLMHKFDDDNHSGESNKETSDKEVSKLNSQLYTINELKQCSESYFKKHADSSKSDSKSRKYQGLLKYEANYKMLIVNNKPLYVDDYDDGVQDRFLIVYTNHKFVDSVKFAGSVYEHIKSKQFPIESMYYESLVTPVRLFLSHVLMYRRDPKTGFVVYKTLLSNDPMHKHNLMCLSTNNSPLYALIYILNIKTVRSATITIGEDKMEEMIGIAVQHFKNFLHPSFVQYNYKKNINASSSKSFVFNEQVLLQQIKNKFKNNYNKTTNVFYNMTMALNRNDLNTSVPNFVC

Annotated regions:
Protein sequence:
MYYPFVRKALFQLDPERAHEFTFQQLRRVTGTPLEALVRQKVPAKPVSCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQTIHHKYVPIAVKIAPDLSEDELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDETGGLSGRPLQLKSTEIIRRLSQELKEQLPIIGVGGIDSVIAAREKMAAGATLVQIYSGFIFKGPQLIKEIVTHI

Annotated regions:
phrase: IIGVGGIDSVIAAREKMAAG
type: CONSERVED_SITE
name: Dihydroorotate_DH_CS
description: Dihydroorotate dehydrogenase, conserved site

phrase: VSCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQTIHHKYVPIAVKIAPDLSEDELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDETGGLSGRPLQLKSTEIIRRLSQELKEQLPIIGVGGIDSVIAAREKMAAGATLVQIYSGFIFKGPQLIKEIVT
type: DOMAIN
name: Dihydroorotate_DH_cat
description: Dihydroorotate dehydrogenase, catalytic

phrase: GSIEIGTVTPRPQPGNDKP
type: CONSERVED_SITE
name: Dihydroorotate_DH_CS
description: Dihydroorotate dehydrogenase, conserved site
Protein sequence:
MQTPLIDLRAIRKSYGGGDSPLVNVLRGIDLSIHAGEFVAIVGASGSGKSTLMNILGCLDRPTSGEYLFAGENVAELGSDELAWLRREAFGFVFQGYHLIPSGSAQENVEMPAIYAGTPAAERHARAAALLDRLGLGSRTGNRPHQLSGGQQQRVSIARALMNGGHIILADEPTGALDSHSGAEVMALLDELASQGHVVILITHDREVAARAKRVIEISDGLVVSDTACDLSAPRSANPAALQAVDLRKRLSEGSGSRGAWKGELLDAVQAAWRVMWINRFRTALTLLGIVIGVASVVVMLAVGEGSKRQVMAQMSSFGSNIIYLNGKAPNPRAPKGIITLDEVAALGELPEVKMIMPVNGGQAGVRYGNVDHSSYVGGNDTHFPAIFNWPVVEGSYFSEADEQSAAAVAVIGYKVRQKLFGEHTDPIGQYILIENVPFQVVGVLEEKGATSGDLDSDNRIAIPYSAASIRLFGSQDPEYITIATRDANNVKHAEEAIRNLLQRLHNGKQDYELTNNAAMIQAEARTQNTLSLMLGSIAAISLLVGGIGVMNIMLMTVRERTREIGIRMATGARQSDILRQFLTEAVMLSVVGGLAGVVLALGMGAALLLSKVAVAFTVPAVAGAFACALVTGVIFGFMPARKAARLDPVAALTSE

Annotated regions:
phrase: SIAAISLLVGGIGVMNIMLMTVRERTREIGIRMATGARQSDILRQFLTEAVMLSVVGGLAGVVLALGMGAALLLSKVAVAFTVPAVAGAFACALVTGVIFGFMPARKAARLD
type: DOMAIN
name: ABC3_permease_C
description: ABC3 transporter permease, C-terminal

phrase: LRGIDLSIHAGEFVAIVGASGSGKSTLMNILGCLDRPTSGEYLFAGENVAELGSDELAWLRREAFGFVFQGYHLIPSGSAQENVEMPAIYAGTPAAERHARAAALLDRLGLGSRTGNRPHQLSGGQQQRVSIARALMNGGHIILADEP
type: DOMAIN
name: ABC_transporter-like_ATP-bd
description: ABC transporter-like, ATP-binding domain

phrase: IDLRAIRKSYGGGDSPLVNVLRGIDLSIHAGEFVAIVGASGSGKSTLMNILGCLDRPTSGEYLFAGENVAELGSDELAWLRREAFGFVFQGYHLIPSGSAQENVEMPAIYAGTPAAERHARAAALLDRLGLGSRTGNRPHQLSGGQQQRVSIARALMNGGHIILADEPTGALDSHSGAEVMALLDELASQGHVVILITHDREVAARAKRVIEISDGLVVSDTACDLSAPRSANPAALQA
type: DOMAIN
name: ABC_transporter-like_ATP-bd
description: ABC transporter-like, ATP-binding domain

phrase: TALTLLGIVIGVASVVVMLAVGEGSKRQVMAQMSSFGSNIIYLNGKAPNPRAPKGIITLDEVAALGELPEVKMIMPVNGGQAGVRYGNVDHSSYVGGNDTHFPAIFNWPVVEGSYFSEADEQSAAAVAVIGYKVRQKLFGEHTDPIGQYILIENVPFQVVGVLEEKGATSGDLDSDNRIAIPYSAASIRLFGSQDPEYITIATRDANNVKHAEEAIRN
type: DOMAIN
name: MacB_PCD
description: MacB-like periplasmic core domain

phrase: LSGGQQQRVSIARA
type: CONSERVED_SITE
name: ABC_transporter-like_CS
description: ABC transporter-like, conserved site

phrase: IDLRAIRKSYGGGDSPLVNVLRGIDLSIHAGEFVAIVGASGSGKSTLMNILGCLDRPTSGEYLFAGENVAELGSDELAWLRREAFGFVFQGYHLIPSGSAQENVEMPAIYAGTPAAERHARAAALLDRLGLGSRTGNRPHQLSGGQQQRVSIARALMNGGHIILADEPTGALDSHSGAEVMALLDELASQGHVVILITHDREVAARAKRVIEISDGL
type: DOMAIN
name: MacB-like_ATP-bd
description: MacB-like, ATP-binding domain

phrase: AGEFVAIVGASGSGKSTLMNILGCLDRPTSGEYLFAGENVAELGSDELAWLRREAFGFVFQGYHLIPSGSAQENVEMPAIYAGTPAAERHARAAALLDRLGLGSRTGNRPHQLSGGQQQRVSIARALMNGGHIILADEPTGALDSHSGAEVMALLDELASQGHVVILITHDREVAARAKRVIEISDG
type: DOMAIN
name: AAA+_ATPase
description: AAA+ ATPase domain
Protein sequence:
MTKRIRTALCVIVSVLFLASCSSRPDGMHVILFSDMQAGVQEKIKKAAEQNAGKVDIFPAFQEKLLTEITAHEGDVFIVPEDMFQAYDDPENFQPLNGLPPEKTSPYTTVNKKTGEKTIYAVQIEKGKKQLNGYSFQLNRDMAAFIPVYAEKTEEALQLISQLTEAR

Annotated regions:
Protein sequence:
MEPMPSATDGGDRSATPSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEENQTKSKPLDSDILNPLGVPSVSKRVVLGDSVDGGVTDYQPSGGADIRGAQLGDKLDSFIKAPECSSKDGVELRQRNRGDLTADSAPRGSHHGLEQYLSRFEEAMKLRKQLISEKPSQEDGRTTEEFDSFRIFRLVGCALLALVVRAFVCKYLSIFAPFLTLQLAYMGLYKYFPKGEKKVKTTVLTAALLLSGIPAEVINRSMDTYSKMGEVFTDLCVYFFTFIFCHEVLEYWGPEVP

Annotated regions:
Protein sequence:
MTAILAKNEASSLWARFCEWITSTENRLYIGWFGVIMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAVVPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFFLGICCYMGREWELSYRLGMRPWIAVAYSAPVAAATAVFIIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVLNTWADIINRANLGMEVMHERNAHNFPLDLASVEAPSVNA

Annotated regions:
phrase: NILMHPFHMLGVAGVFGGSLFSAMHG
type: CONSERVED_SITE
name: Photo_RC_L/M_CS
description: Photosynthetic reaction centre, L/M, conserved site
Protein sequence:
MTTRPTTTTTAAAATTAPRHPALTASDPELAALIGAEERLQADTLRLIPSENYVSAAVLEASGTVLQNKYSEGYPGKRYYEGQQVIDQVETLAIRRAQALFGMDHANVQPYSGSPANLAAYLAFLQPGDTVLGMSLPMGGHLTHGWDVSATGRWFRGVRYGVRRDTGRIDLDEVRDLARAERPKLIFCGGTAVPRTIDFAGFAEIARETGAVLVADIAHIAGLIAGGAHPSPAGHADVVSTTTHKTLRGPRGAMLLSTAEHARAIDRAVFPGLQGGPHNQTTAAIAVALGEAATAGFCSYAHQVVANARALGEELAARGFDLVSGGTDNHLLLIDLTDKDVPGKTAAKALDRAGIVVNYNTVPYDPRKPFDPSGIRIGTPALTSRGVPASAMGTVATWITTAVDAARAGDEAAIRKVRGEVKELMDAYPAPGLPVG

Annotated regions:
phrase: DVVSTTTHKTLRGPRG
type: BINDING_SITE
name: Ser_HO-MeTrfase_PLP_BS
description: Serine hydroxymethyltransferase, pyridoxal phosphate binding site

phrase: TASDPELAALIGAEERLQADTLRLIPSENYVSAAVLEASGTVLQNKYSEGYPGKRYYEGQQVIDQVETLAIRRAQALFGMDHANVQPYSGSPANLAAYLAFLQPGDTVLGMSLPMGGHLTHGWDVSATGRWFRGVRYGVRRDTGRIDLDEVRDLARAERPKLIFCGGTAVPRTIDFAGFAEIARETGAVLVADIAHIAGLIAGGAHPSPAGHADVVSTTTHKTLRGPRGAMLLSTAEHARAIDRAVFPGLQGGPHNQTTAAIAVALGEAATAGFCSYAHQVVANARALGEELAARGFDLVSGGTDNHLLLIDLTDKDVPGKTAAKALDRAGIVVNYNTVPYDPRKPFDPSGIRIGTPALTSRGVPASAMGTVATW
type: DOMAIN
name: SHMT-like_dom
description: Serine hydroxymethyltransferase-like domain
Protein sequence:
MITKQSSNESFDVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADLTALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTPNLKIREAMVTGLEVEHYPNQIDQKTPEIQERIGFIKGIKTYFGSVFHAKAVVLTTGTFLGGRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLSDASDKFFSFDPLSWKSGEQMSCHITRTTKQTHQLIKNNLHLTPIYGGFIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPEGRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPAYAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEAAAQGLVAGLNAARLVNNKEGIIFERESSYIGTMIDDLVTKDLKEPYRVLTSRSEYRLILRGDNADRRLTPLGYQLGLIDERRWKIFNAKQQLINQEKERLEKERIKESDKSAKEIYSSTGTPIKGSLTLANFLRRTNIHYKDLITFNLTTQSIPLDVEEGVEIDIKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIETLSKEAREKLTISQPKSLGHAAQLPGVSKADLTALLVWLKIEKMKKVKRKDSLQITN

Annotated regions:
phrase: ERRWKIFNAKQQLINQEKERLEKERIKESDKSAKEIYSSTGTPIKGSLTLANFLRRTNIHYKDLITFNLTTQSIPLDVEEGVEIDIKYSGYLERQ
type: DOMAIN
name: GIDA_C_N
description: tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal, N-terninal subdomain

phrase: DVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADLTALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTPNLKIREAMVTGLEVEHYPNQIDQKTPEIQERIGFIKGIKTYFGSVFHAKAVVLTTGTFLGGRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLSDASDKFFSFDPLSWKSGEQMSCHITRTTKQTHQLIKNNLHLTPIYGGFIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPEGRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPAYAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEAAAQGLVAGLNAARLVNNK
type: DOMAIN
name: MnmG_N
description: MnmG, N-terminal domain

phrase: QLKQQSKKLLPKNLNYNNIETLSKEAREKLTISQPKSLGHAAQLPGVSKADLTAL
type: DOMAIN
name: MnmG_C
description: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal

phrase: AGQLNGTTGYEEAAAQGLVAGLN
type: CONSERVED_SITE
name: MnmG-rel_CS
description: MnmG-related, conserved site

phrase: IKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIETLSKEAREKLTISQPKSLGHAAQLPGVSKADLTALL
type: DOMAIN
name: MnmG_C_subdom
description: tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain

phrase: GPRYCPSIEDKIVR
type: CONSERVED_SITE
name: MnmG-rel_CS
description: MnmG-related, conserved site