nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
METKTAKLLDGKAIAAKIQQELSVAITQLQPEIGRPPGLAVLMVGDNPASAAYVRNKEKACAKVGIASFGKHFPAETTFRELEKVIAALNDDERVDGILVQLPLPDHLDAVALLHQIDPDKDADGLHPVNLGRLVRGEIGLRSCTPDGVMRLLQEYEIPLQGKQAVVVGRSILVGKPMALMLLEADATVTIAHSRSHDLKSITQNADILIAAAGRPGLITADMVKPGAVVVDVGMNRVTDASGKSRLIGDVDFESTAGVAGFITPVPGGVGPMTVAILLQNTFTSYSRAAKK

Annotated regions:
phrase: PGGVGPMT
type: CONSERVED_SITE
name: THF_DH/CycHdrlase_CS
description: Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site

phrase: LDGKAIAAKIQQELSVAITQLQPEIGRPPGLAVLMVGDNPASAAYVRNKEKACAKVGIASFGKHFPAETTFRELEKVIAALNDDERVDGILVQLPLPDHLDAVALLHQIDPDKDA
type: DOMAIN
name: THF_DH/CycHdrlase_cat_dom
description: Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain

phrase: PDKDADGLHPVNLGRLVRGEIGLRSCTPDGVMRLLQEYEIPLQGKQAVVVGRSILVGKPMALMLLEADATVTIAHSRSHDLKSITQNADILIAAAGRPGLITADMVKPGAVVVDVGMNRVTDASGKSRLIGDVDFESTAGVAGFITPVPGGVGPMTVAILLQNTFTS
type: DOMAIN
name: THF_DH/CycHdrlase_NAD-bd_dom
description: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain

phrase: HPVNLGRLVRGEIGLRSCTPDGVMRLLQEYEIPLQGKQAVVVGRSILVGKPMALMLLEADATVTIAHSRSHDLKSITQNADILIAAAGRPGLITADMVKPGAVVVDVGMNRVTDASGKSRLIGDVDFESTAGVAGFITPVPGGVGPMTVAILLQNTFTSYS
type: DOMAIN
name: THF_DH/CycHdrlase_NAD-bd_dom
description: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
Protein sequence:
MLLLLAEFLQQFYKGFAVFQYLSLRGILGVLTALTLSLCLGPWMIRTLQMRQIGQSVRNDGPQSHLSKSGTPTMGGALILSSIGISTLLWADLSNRYVWVVLLVTLLFGAIGWVDDYRKVIEKNSRGLPSRWKYFWQSVFGLCAAIFLYTTAPSATETTLIVPMLKDVRIPLGIGFIVLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVGGALGIFCYLSGNVKFAEYLLIPYVPGAGELIVFSGALIGAGLGFLWFNTYPAQVFMGDVGALALGAALGTMAVIVRQEIVLFIMGGVFVMETLSVVIQVASFKLTGRRVFRMAPIHHHFELKGWPEPRVIVRFWIITVILVLIGLATLKLR

Annotated regions:
phrase: KSGTPTMGGALI
type: CONSERVED_SITE
name: PNAcMuramoyl-5peptid_Trfase_CS
description: Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site

phrase: KSGTPTMGGALI
type: CONSERVED_SITE
name: PNAcMuramoyl-5peptid_Trfase_CS
description: Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site

phrase: NAVNLTDGLDG
type: CONSERVED_SITE
name: PNAcMuramoyl-5peptid_Trfase_CS
description: Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site
Protein sequence:
MPFSLPDLSGRHVILGVTGSIAAYKAAPLVRRLKKAGAEVQVLMTPDAERFIPPLTLGTLSEKEVLTEIFPENEDGSWTKHVTLGKWADLFVVAPATAQTIAKLAHGFCDSMLTATALSARCPLLVCPAMDRDMYRHAATQNNLEQLREIGYEVVPAEHGELASGLVGQGRMPEPEAILNRVAAMLSAKESSGDQASGPDSAPLAGHNVLVTAGPTQEPLDPVRVLTNPSTGTMGYALAEAAARRGASVTLVTGPTTLAPPSAVEVIEVQTAADMNEAVQARREDADFVFMAAAVADYTPTDPSASKRKKNDTDEDLVLHLRRTPDILKTLGAHKRPDQVLVGFALETDDALENARRKLNKKNLDWIAVNNPMEDGAGFGASTNRVTLLPRDGAPEELPLMPKPDVAEVLLDRVLASQQEQGS

Annotated regions:
phrase: HVILGVTGSIAAYKAAPLVRRLKKAGAEVQVLMTPDAERFIPPLTLGTLSEKEVLTEIFPENEDGSWTKHVTLGKWADLFVVAPATAQTIAKLAHGFCDSMLTATALSARCPLLVCPAMDRDMYRHAATQNNLEQLREIGYEVVPAEHGELASGLVGQGRMPEPEAILNRVAA
type: DOMAIN
name: Flavoprotein
description: Flavoprotein

phrase: LAGHNVLVTAGPTQEPLDPVRVLTNPSTGTMGYALAEAAARRGASVTLVTGPTTLAPPSAVEVIEVQTAADMNEAVQARREDADFVFMAAAVADYTPTDPSASKRKKNDTDEDLVLHLRRTPDILKTLGAHKRPDQVLVGFALETDDALENARRKLNKKNLDWIAVNNPMEDGAGFGASTNRVTL
type: DOMAIN
name: DNA/pantothenate-metab_flavo_C
description: DNA/pantothenate metabolism flavoprotein, C-terminal
Protein sequence:
MEKKETTYFGNKVIPAEEKKHRVLEIFTSVADKYDLMNDLMSFGTHRLWKRFVAEKTNLKPGDSAIDVCGGTADIAMLMAKKVSEKGKVVVYDINKEMLEFGRDKCIDKGFLKNIQYVQGDAEEIGFEDNTFNCATVGFGIRNVTHLEKAFKEMMRVVKPGGRVICLEFSHPTSKTFSKLYDLYSFKIMPEIGGIVTGNRDAYTYLPESIRKFPTQEELKKIMEGVGLFKVKYYNLFNGIAAVHVGVKV

Annotated regions:
phrase: YDLMNDLMSFGTHRL
type: CONSERVED_SITE
name: UbiE/COQ5_MeTrFase_CS
description: UbiE/COQ5 methyltransferase, conserved site

phrase: RVVKPGGRVICLEF
type: CONSERVED_SITE
name: UbiE/COQ5_MeTrFase_CS
description: UbiE/COQ5 methyltransferase, conserved site
Protein sequence:
MTHIHADSEGCASLTWPNGFRAYTGHGGMRDRGDDISIVASDRPSVSAAMFTRSRFAGPAVVLSRAHAAGQHLRALCTLAKNANVATGRQGEENAAEVVRRVAGILDIPEGEVLIGSTGVIGRPLPMDTIRAHLDETAQRGPAAFEAGPLDVARAMMTTDTRPKTAERTVGPARIVGVAKGVGMLEPDMATMLAYVFTDAALAPGDLDAALRGAVDKTFNCLSVDTDTSTSDTVALIANGAAGPVDLAAFSLALADLCLDLTTQLAGDGEGATKLLRVTVGRARDYRQAKRVAKTVVNSPLVKTAVHGADPNWGRVVMAIGKNSDDTDIEPNKVTVRFGPIEVYPREPEPDTLDQLVDIMRRDEVDITITLGLGDATATVYGCDLSEGYIRVNADYTS

Annotated regions:
Protein sequence:
MASKRALVILAKGAEEMETVIPVDVMRRAGIKVTIAGLAGKDPVQCSRDVVICPDASLEDAKKQGPYDVVVLPGGNLGAQNLSESAAVKEILKEQEKRKGLIAAICAVDLGGNKTLWNSETACSSKSLCQKVFVPARSQQESVRHKHCSSALCLPWLPRPRGAFRLISSVERWALGILLSATGFRRRSLVLCRCPHVFEI

Annotated regions:
phrase: KRALVILAKGAEEMETVIPVDVMRRAGIKVTIAGLAGKDPVQCSRDVVICPDASLEDAKKQGPYDVVVLPGGNLGAQNLSESAAVKEILKEQEKRKGLIAAICA
type: DOMAIN
name: DJ-1/PfpI
description: DJ-1/PfpI
Protein sequence:
MSFDTFQKTLEYAKKLDEKDHLARFRKEYYGKPGSIYMDGNSLGLLSKRAERTLLSSLNDWKEHGIDGWTDGESPWFYMAETLGEHMAPIIGAAPEEVIVTGSTTVNLHQLVSTFYKPNGVRTKILADELTFPSDIYALQSQLLHYGYNPEEHLIRVQSPDGRYLVEEDIIAAMGEEVALIVLPTVLYRSGQILDIKRLTYEAHKKGILIGFDACHSVGSIPHTFSKCGIDFAFWCNYKYLNGGPGAAGGLYVNRKHFGTLPGLAGWFGSQKEKQFDMEHTLTPASSAGAYQMGTPHILSMAPLLGSLEIFAEAGIENIREKSLGLTTYFMQLIEKELSEWDFVIGNPREDYRRGGHVSLEHKEAARICKALKVNGVIPDFRAPNIIRLAPIALYSTYEEVWRVVQVLKKIMNEKQYEKFTNDRNIVA

Annotated regions:
Protein sequence:
MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVCGFIFTTLFGCRNVNLD

Annotated regions:
phrase: ILTRVGGPGNIASCGNCMTRLRLGVHDSSLV
type: CONSERVED_SITE
name: PTrfase_EIIB_Cys
description: Phosphotransferase system EIIB, cysteine phosphorylation site

phrase: IFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFVTACLG
type: DOMAIN
name: PTS_EIIC
description: Phosphotransferase system, EIIC

phrase: SELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSEL
type: CONSERVED_SITE
name: PTrfase_EIIB_Cys
description: Phosphotransferase system EIIB, cysteine phosphorylation site

phrase: NIASCGNCMTRLRLGVH
type: CONSERVED_SITE
name: PTrfase_EIIB_Cys
description: Phosphotransferase system EIIB, cysteine phosphorylation site

phrase: SELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPV
type: DOMAIN
name: PTS_IIB_1
description: Phosphotransferase system, IIB component, type 1

phrase: AKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPFGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVCGFIFTTLFGCRNVNL
type: DOMAIN
name: PTS_EIIC_1
description: Phosphotransferase system, EIIC component, type 1
Protein sequence:
MNWLRNSLIAAILVITYVLFIRWNEFSERQQVPTIANQPAAVTTPAYEAVPSDDAVASSATEESDVPEVSVSAEPVAAPKAVYQPKLVTVKTDVLEVQIDTNGGDVLQVVLLKHLADKADDNQPFVLMTQNSAHTYVARSGLAGGNGPDGAKKGRAKYSVAKTNYSLNSDDQVVVDLTLDQENAQITKRFTFTKSSYLIDVEYIITNRADTPWAAKLYGQIIRDGSEPSYGYMGMRPYLGAAITTPEVNYEKVSFDDMDDGPFKVEQKGGWVSLIQHYFISAWIPPKDATNSYELSKSSKGNYVLRFISETTTVAPHSVGTVKAGFYAGPKNIRRLEEISPHLDLTIDYSFLWFIAKPLFFALDFIHGLVGNWGVAIILLTVLIKAVFFYPSAMSYRSMAKMRKLQPMMAELKERYGEDKQKMSGELMKLYKKEKVNPFGGCLPILLQMPVFISLYWMIMESVELRHQPFFLWIQDLSVKDPLFILPLLMGVTMYIQQKLNPTPPDPMQAKVMQMMPIGFTFLFMFFPAGLVLYWVVNNTLSISQQYVITRNIEKAG

Annotated regions:
phrase: WGVAIILLTVLIKAVFFYPSAMSYRSMAKMRKLQPMMAELKERYGEDKQKMSGELMKLYKKEKVNPFGGCLPILLQMPVFISLYWMIMESVELRHQPFFLWIQDLSVKDPLFILPLLMGVTMYIQQKLNPTPPDPMQAKVMQMMPIGFTFLFMFFPAGLVLYWVVNNTLSISQQYVIT
type: DOMAIN
name: YidC/Oxa/ALB_C
description: Membrane insertase YidC/Oxa/ALB, C-terminal

phrase: GVAIILLTVLIKAVFFYPSAMSYRSMAKMRKLQPMMAELKERYGEDKQKMSGELMKLYKKEKVNPFGGCLPILLQMPVFISLYWMIMESVELRHQPFFLWIQDLSVKDPLFILPLLMGVTMYIQQKLNPTPPDPMQAKVMQMMPIGFTFLFMFFPAGLVLYWVVNNTLSISQQYVIT
type: DOMAIN
name: YidC_ALB_C
description: Membrane insertase YidC/ALB, C-terminal

phrase: KLVTVKTDVLEVQIDTNGGDVLQVVLLKHLADKADDNQPFVLMTQNSAHTYVARSGLAGGNGPDGAKKGRAKYSVAKTNYSLNSDDQVVVDLTLDQENAQITKRFTFTKSSYLIDVEYIITNRADTPWAAKLYGQIIRDGSEPSYGYMGMRPYLGAAITTPEVNYEKVSFDDMDDGPFKVEQKGGWVSLIQHYFISAWIPPKDATNSYELSKSSKGNYVLRFISETTTVAPHSVGTVKAGFYAGPKNIRRLEEISPHLDLTID
type: DOMAIN
name: Membr_insert_YidC_N
description: Membrane insertase YidC, N-terminal

phrase: VTVKTDVLEVQIDTNGGDVLQVVLLKHLADKADDNQPFVLMTQNSAHTYVARSGLAGGNGPDGAKKGRAKYSVAKTNYSLNSDDQVVVDLTLDQENAQITKRFTFTKSSYLIDVEYIITNRADTPWAAKLYGQIIRDGSEPSYGYMGMRPYLGAAITTPEVNYEKVSFDDMDDGPFKVEQKGGWVSLIQHYFISAWIPPKDATNSYELSKSSKGNYVLRFISETTTVAPHSVGTVKAGFYAGPKNIRRLEEISPHLDLTIDYSFLWFIAKPLF
type: DOMAIN
name: Membr_insert_YidC_N
description: Membrane insertase YidC, N-terminal

phrase: NWGVAIILLTVLIKAVFFYPSAMSYRSMAKMRKLQPMMAELKERYGEDKQKMSGELMKLYKKEKVNPFGGCLPILLQMPVFISLYWMIMESVELRHQPFFLWIQDLSVKDPLFILPLLMGVTMYIQQKLNPTPPDPMQAKVMQMMPIGFTFLFMFFPAGLVLYWVVNNTLSISQQYVIT
type: DOMAIN
name: YidC/Oxa/ALB_C
description: Membrane insertase YidC/Oxa/ALB, C-terminal

phrase: RNSLIAAILVITYVLFIRWNEFSERQQVPTIANQPAAVTTPAYEAVPSDDAVASSATEESDVPEVSVSAEPVAAPKAVYQPKLVTVKTDVLEVQIDTNGGDVLQVVLLKHLADKADDNQPFVLMTQNSAHTYVARSGLAGGNGPDGAKKGRAKYSVAKTNYSLNSDDQVVVDLTLDQENAQITKRFTFTKSSYLIDVEYIITNRADTPWAAKLYGQIIRDGSEPSYGYMGMRPYLGAAITTPEVNYEKVSFDDMDDGPFKVEQKGGWVSLIQHYFISAWIPPKDATNSYELSKSSKGNYVLRFISETTTVAPHSVGTVKAGFYAGPKNIRRLEEISPHLDLTIDYSFLWFIAKPLFFALDFIHGLV
type: DOMAIN
name: Membr_insert_YidC_N
description: Membrane insertase YidC, N-terminal
Protein sequence:
MKRRSGDRENRRKGKSLFPASPLPRFSGSRFSVPGFKAAGIACGIKKNNKKDLALIFSEAPATVAGLFTTNKIKAAPVLVDMQRIKKGVCHAVIINSGNANACTGKKGMTAAVKTVTLIEKALDIKKGLAMVSSTGVIGELLPVVNGIEKGIPKLIDALSEEGWDNAAKAIMTTDAFPKIAFEKGKIDGKEVSMLGIAKGAGMICPDMATMLAYIVTDAAVEQNALQNALKNAVNKSFNSITVDGDTSTNDTVLALANGKAGNRPVGSKQYAVSSKDYKTFCGMLEKVCLKLAHMIVRDGEGATKFLEIKVKGAKKEADAKNIALVIANSLLVKTAFFGEDANWGRIMAAIGRAGVDIIGEKISIYFNNTPVVKNGSGTSRDKEADKVIKKKDICLTVDLGMGKAGATVWTTDLTYEYVKINAAYRT

Annotated regions:
Protein sequence:
MNSCKRFPRSARICLPSEYYVAFEQGRRYSSVLLRLHHLPTSGPVRLGLVVSRRVDIRAVNRNRIKRALREVMRQIAYKLVPGDYVVVVRQTAKDVSNAELSVALLSLLRRIGALPLASIDNAMLPFFERNCSRK

Annotated regions:
phrase: DIRAVNRNRIKRAL
type: CONSERVED_SITE
name: RNase_P_CS
description: Ribonuclease P, conserved site
Protein sequence:
QVHSSRKLPPGPFPLPIVGNFFQLELNDVPKSFTRLAERFGPVFTLYLGSNRVVVLHGYQAVKEVLLQHKKEFSGRGEYHAYRAHKDQGVTFNNGLTWKETRRASLTILRDFGMGKEGNEARIQREIPFLLEALRKTQGQPFDPTFVVGSAPCNVIADILFRKRFDYEDRACLRLQTLFNENLYLLSTPWLLLHNNFPSLINCLPGSHRKIMRNVSELKDYSLARLKEHLQTLAPGCPRDFSDRLLMEMEKEKYKAEPGYNMGNIASTVADLFFAGTVTTSATLKHGLLVLMKHPEVEEKLHEEIDRVIGPHRIPSVKDKLEMPYMDAVVHEIQRFTNLLPSNLNHEATEDTAFRGYVIPKGTILIPTLDSLLFDNQEFPDPDKFKPEHFLDEKGKFKYSDHFKAFSAGRRVCVGEGLARMELFLFFTAILQHFNLKSLVDPKDIDL

Annotated regions:
phrase: FSAGRRVCV
type: CONSERVED_SITE
name: Cyt_P450_CS
description: Cytochrome P450, conserved site
Protein sequence:
MKTLHVELGERGYPIYIGRGLLGHPDLIQAHLPGGQVLVVTNEVVAPLYLDRMLASLAGKDTGSVVLPDGEAHKTLDSAMAVFDALLARRFGRNAAIVALGGGVIGDLAGFAAACYQRGVPFIQVPTTLLSQVDSSVGGKTAVNHPRGKNMIGAFYQPRCVLADTDTLDTLPDRELSAGLAEVIKYGFIRDPEFLAWLEANVERLLQRDPEALAYAIERSCINKAEIVAEDETETGVRATLNLGHTFGHAIETGMGYGVCLHGEAVAIGMCQAADLSRRLGWIGDDEVARVIRLLERARLPVVPPRELDADAFLEHMAVDKKNVDGGLRLVLLKSLGEATLPVAVDAGLLRATLECYGR

Annotated regions:
phrase: GLAEVIKYGFIRDPEFLAWLEANVERLLQRDPEALAYAIERSCINKAEIVAEDETETGVRATLNLGHTFGHAIETGMGYGVCLHGEAVAIGMCQAADLSRRLGWIGDDEVARVIRLLERARLPVVPPRELDADAFLEHMAVDKK
type: DOMAIN
name: DHQS_C
description: 3-dehydroquinate synthase, C-terminal domain

phrase: VVLPDGEAHKTLDSAMAVFDALLARRFGRNAAIVALGGGVIGDLAGFAAACYQRGVPFIQVPTTLLSQVDSSVGGKTAVNHPRGKNMIGAFYQPRCVLADTDTLDTLPDREL
type: DOMAIN
name: DHQS/DOIS_N
description: 3-dehydroquinate synthase, N-terminal domain
Protein sequence:
MKGNIFLVGLMGAGKTTVGRALAKKLNKLFIDSDHEIEARTGVSIPLIFEIEGEESFRQREAEVIRDLSARRGIVLATGGGAILKPENRAYLKSRGTVIYLRASVHNILQRTSRDKSRPLLQTADPRRRLEELSRQREPFYREVADIVIDTGRPNVQFLVHSILSQLDLLPDDPDTEADIAQSVGSQVSGATNISPNFPMTQPVSSQNHAPTISLQVELGERSYPIEIGSSLLGDRERIARLISGRQVAVVTNTTVAPLYLQRLTQTLQEAGKSVLEIILPDGEEEKNWASLMQIFDRLLAAKCDRKTTLIALGGGVIGDLTGFAASAYMRGIPFVQIPTTLLAQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADTLTLHTLPDRELSAGLAEVIKYGAVIDAAFFKWIEDNIDKLMARDNAALAYAIRRSCELKADVVRQDEREGGLRAILNFGHTFGHAIESGLGYGKWLHGEAVGCGMVMAADLSHRLGHITAIDKERLCALVRAAGLPTEAPNLGVQRWLELMQVDKKNEGGQIRFILMKPLGSYLISAAPQDALLATIQQLASGDMSR

Annotated regions:
phrase: GLAEVIKYGAVIDAAFFKWIEDNIDKLMARDNAALAYAIRRSCELKADVVRQDEREGGLRAILNFGHTFGHAIESGLGYGKWLHGEAVGCGMVMAADLSHRLGHITAIDKERLCALVRAAGLPTEAPNLGVQRWLELMQVDKK
type: DOMAIN
name: DHQS_C
description: 3-dehydroquinate synthase, C-terminal domain

phrase: IILPDGEEEKNWASLMQIFDRLLAAKCDRKTTLIALGGGVIGDLTGFAASAYMRGIPFVQIPTTLLAQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADTLTLHTLPDREL
type: DOMAIN
name: DHQS/DOIS_N
description: 3-dehydroquinate synthase, N-terminal domain

phrase: RQREAEVIRDLSARRGIVLATGGGA
type: CONSERVED_SITE
name: Shikimate_kinase_CS
description: Shikimate kinase, conserved site
Protein sequence:
MVTLNNIIKGVEVLSVSGDYSRIIEGVEFDSRKVGSGNLFVAVRGTKSDGHEFIQPALRAGAVAVLCEKLPADPDPSVCWITTPDSAAALGVVCSNYYGNPSDQLKLVGVTGTNGKTTIATLLYRMFTKLGYKCGLFSTVCNYLNEKQLPATHTTPDPVQLNAILARMVEEGCDYAFMEVSSHAVDQKRIAGLRFAGGIFTNLTHDHLDYHVTFSNYLRAKKSFFDSLPPSAFAITNIDDRNGRIMLQNCSARQYTFSVRGMADYRCNIIEQDFTGMGLRIQGEEVWTKFIGDYNASNLLAVYAASELLGAGKQEILTILSDLSHVPGRLEAVSPESGITALVDYAHTPDALLNVIETINRIRQEGRQLLTVVGAGGDRDRTKRPKMAFISAEGSSKVILTSDNPRTENPERILDDMEAGITPDQKHKVLRIADRREAIKTAVMLAQKGDIILVAGKGHEPYQEIMGIRHHFDDREELETALKMKK

Annotated regions:
phrase: IEGVEFDSRKVGSGNLFVAVRGTKSDGHEFIQPALRAGAVAVLCEKL
type: DOMAIN
name: Mur_ligase_N
description: Mur ligase, N-terminal catalytic domain

phrase: VTGTNGKTTIATLLYRMFTKLGYKCGLFSTVCNYLNEKQLPATHTTPDPVQLNAILARMVEEGCDYAFMEVSSHAVDQKRIAGLRFAGGIFTNLTHDHLDYHVTFSNYLRAKKSFFDSLPPSAFAITNIDDRNGRIMLQNCSARQYTFSVRGMADYRCNIIEQDFTGMGLRIQGEEVWTKFIGDYNASNLLAVYA
type: DOMAIN
name: Mur_ligase_cen
description: Mur ligase, central

phrase: GRLEAVSPESGITALVDYAHTPDALLNVIETINRIRQEGRQLLTVVGAGGDRDRTKRPKMAFISAEGSSKVILTSDNPRTENPERILDDMEAGITPDQKHKVLRIADRREAIKTAVMLAQKGDIILVAGK
type: DOMAIN
name: Mur_ligase_C
description: Mur ligase, C-terminal
Protein sequence:
MTTIADTIVEIIQDAGVERVYGLPGDSLNGFTDAIRRTKGDVAWAHVRHEEAAAFAAAAEAALTGELTVCAGSCGPGNLHLINGLYDANRSRVPVLAIAAHIPASEIGTGYFQETHPQELFRECSVYTELVSVPEQLPRVLEIAMRAAIEKRGVAVVVIPGEIFLHASAGRPKSAPIVRAATLSRPADAELEKAAAILNGAKKVTILGGAGVQGSHDEVVALAERLKAPIVHALRGKEFLEYDNPYDVGMTGLLGFASGYRAMEDCDALLMLGTDFPYPQFFPSKATVIQLDIRGEQIGKRTPIDLGLVGDVGDTARALLPLLDEKAHTSHHLDSSVAHYAKSRKGLDELADNDRNRTPIHPQYVARLVSELATDDAVFIPDVGSPVVWAARYLRMNGRRRLIGSFSHGTMANALPHAIGAQSAFPDRQVVALSGDGGLAMLFGELLTVRQSKLPVKIVVFNNSSLNFVEVEMKAAGFVNYGTELDNPDFAAVAASLGIFGRRVEKPDDLEGALRDAFAHDGPALVDVVTARQELSIPPTVSVEQAKGFGLYAIRTIMSGRGDELIDLADTNVFRRLFS

Annotated regions:
phrase: TIADTIVEIIQDAGVERVYGLPGDSLNGFTDAIRRTKGDVAWAHVRHEEAAAFAAAAEAALTGELTVCAGSCGPGNLHLINGLYDANRSRVPVLAIAAHIPASEIGTGYFQETHPQELFRECSVYTELVSVPEQLPRVLEIAMRAAIEKRGVAVVVIPGE
type: DOMAIN
name: TPP_PYR_POXB-like
description: Pyruvate oxidase POXB-like, pyrimidine-binding domain

phrase: TIADTIVEIIQDAGVERVYGLPGDSLNGFTDAIRRTKGDVAWAHVRHEEAAAFAAAAEAALTGELTVCAGSCGPGNLHLINGLYDANRSRVPVLAIAAHIPASEIGTGYFQET
type: DOMAIN
name: Thiamin_PyroP_enz_TPP-bd_dom
description: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain

phrase: DVGSPVVWAARYLRMNGRRRLIGSFSHGTMANALPHAIGAQSAFPDRQVVALSGDGGLAMLFGELLTVRQSKLPVKIVVFNNSSLNFVEVEMKAAGFVNYGTELDNPDFAAVAASLGIFGRRVEKPDDLEGALRDAFAHDGPALVD
type: DOMAIN
name: TPP_enzyme_TPP-bd
description: Thiamine pyrophosphate enzyme, TPP-binding

phrase: PIHPQYVARLVSELATDDAVFIPDVGSPVVWAARYLRMNGRRRLIGSFSHGTMANALPHAIGAQSAFPDRQVVALSGDGGLAMLFGELLTVRQSKLPVKIVVFNNSSLNFVEVEMKAAGFVNYGTELDNPDFAAVAASLGIFGRRVEKPDDLEGALRDAFAHDGPALVDVVTARQEL
type: DOMAIN
name: TPP_POXB-like
description: Pyruvate oxidase POXB-like, PP-binding domain

phrase: LEKAAAILNGAKKVTILGGAGVQGSHDEVVALAERLKAPIVHALRGKEFLEYDNPYDVGMTGLLGFASGYRAMEDCDALLMLGTDFPYPQFFPSKATVIQLDIRGEQIGKRTPIDLGLVGDVGDTARA
type: DOMAIN
name: Thiamin_PyroP_enz_cen_dom
description: Thiamine pyrophosphate enzyme, central domain

phrase: IGAQSAFPDRQVVALSGDG
type: CONSERVED_SITE
name: TPP-bd_CS
description: TPP-binding enzyme, conserved site
Protein sequence:
MKFYISATGIKKVTISNPGVGIGKGSGGCAAAAAALAARRFSSRTLLLLLLLLAIVLPFIFVRFAFLVLESASVCDSPLDCMGLRLFRGGDTSLKIGEELTRALVEETTDHQDVNGRGTKGSLESFDDLVKEMTLKRRDIRAFASVTKKMLLQMERKVQSAKHHELVYWHLASHGIPKSLHCLSLRLTEEYSVNAMARMRLPPPESVSRLTDPSFHHIVLLTDNVLAASVVISSTVQNAVNPEKFVFHIVTDKKTYTPMHAWFAINSASSPVVEVKGLHQYDWPQEVNFKVREMLDIHRLIWRRHYQNLKDSDFSFVEGTHEQSLQALNPSCLALLNHLRIYIPKLFPDLNKIVLLDDDVVVQSDLSSLWETDLNGKVVGAVVDSWCGDNCCPGRKYKDYFNFSHPLISSNLVQEDCAWLSGMNVFDLKAWRQTNITEAYSTWLRLSVRSGLQLWQPGALPPTLLAFKGLTQSLEPSWHVAGLGSRSVKSPQEILKSASVLHFSGPAKPWLEISNPEVRSLWYRYVNSSDIFVRKCKIMN

Annotated regions:
Protein sequence:
MEDEIATAKDLVAKYLADNEKLSRQKISFLVQTEPRMLLMEGLKLLSLCIELDSCNANGCEHNTESKSVENILHDLGILTPSLCFVVPDGYKLSGNVLILLECFVRSSPANFEQKYTEDLTKLEQLKDDLKSIDINLIPLIDGRTSFYNEQIPDWVNDKLRETLFSLLRFAQESNAXFEESEYVRLCESLSMTSGRLSGVESLNVLTDNRANHYEDIIALCHQGINNKLSAYEVKMQIEEEYQVFRNRIRQGEIEYQFVRVDKGELMCKFNNLYADEGLVDEDNIDHLIYQYXRASPILRFLYADLESERSKXPTVDGGQMQCWRSFLNKVKSLRILNTRRKLMLVFDTLILLASMNDQMKHKGRTXKGWLGSCFVSVNDRLVSLESTKRDLKKWMEKRQQLEVSKSSTLVCKNEILRSVIQKTVTKATAALEAVGICVDHYGVSMDIFDCDVYDLVLKFDVSGVTPTISYQKSQEEKFPYTLGSIGILDPIDLEXLSSLSLALVNSMKTSSTVKIRQNEHGAARYQVVKCKEAYCQEFSLGGIEFQLLYQKTGECSKCYAVNNDAVGEVCSFYADPKRYFPSIFSAEVLHATVETMVSWIEDCSELKEKLIDIKSLTKMILVLILAHPSKRCQKFLQNLRYFVMAYVSDFYHKELIDKXKEKLITETEFLLFRLLRSLLKMVLHEDVKSMLTNRFKFVLNISYMCHFITKETPDRLTDQIKCFEKFLEPKLNFGHVTVNPEDEATSEELDEMIYSAKRFLSKEGCTN

Annotated regions:
phrase: MEDEIATAKDLVAKYLADNEKLSRQKISFLVQTEPRMLLMEGLKLLSLCIELDSCNANGCEHNTESKSVENILHDLGILTPSLCFVVPDGYKLSGNVLILLECFVRSSPANFEQKYTEDLTKLEQLKDDLKSIDINLIPLIDGRTSFYNEQIPDWVNDKLRETLFSLLRFA
type: DOMAIN
name: CapSnatch_arenavir
description: RNA endonuclease, cap-snatching, arenaviral

phrase: VVPDGYKLSGNVLILLECFVRSSPANFEQKYTEDLTKLEQLKDDLKSIDINLIPLIDGRT
type: DOMAIN
name: CapSnatch_bunyavir
description: RNA endonuclease, cap-snatching, bunyaviral
Protein sequence:
MDMGAMSDPERMFFFDLACQNAKVTYEQNPHDADNLTRWGGALLELSQMRNGPESLKCLEDAESKLEEALKIDPMKADALWCLGNAQTSHGFFTSDTVKANEFFEKATQCFQKAVDVEPANDLYRKSLDLSSKAPELHMEIHRQMASQASQAASSTSNTRQSRKKKDSDFWYDVFGWVVLGVGMVVWVGLAKSNAPPQAPR

Annotated regions:
Protein sequence:
MPIRHCIVHLIEKKPDGTPAVLHARDSELAESQAIENMLADLNESYNAKQGKAWGLFHPESGAHPFSGWLKEYLDGGKDFTAFSRVSVEHLQKLMEESNLSVGGHVLFAHYQQGMTDYLAIALLHHSDGVAVNAELDVTPSRHLDLGQLHLAARINISEWQNNKQSKQYISFIKGKNGKKVSEYFRDFIGCQEGVDGPGETRTLLKAFSDFVESEDLPEESAREKTKTLIDYASSQSKMGEPMGLEALSELIDENQPRAFYDHIRNKDYGLSPEIPADKRTLNQFRRFTGRAEGLSISFEAHLLGDKIEYDETAGTLIIKGLPTQLTDQLKRR

Annotated regions:
Protein sequence:
MGNFPAPKNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKNNRDFFQTCRDAEIASEITIQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVPLFGFCGGPWTLMVYMTEGGGSRLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQILQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPMIVFAKGSWYALDKLCCSGFDVVSLDWSWDPREAVKINKNRVTLQGNLDPGVMYGSKEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECHRIGSK

Annotated regions:
phrase: FGFCGGPWTLMVYMTE
type: DOMAIN
name: Uroporphyrinogen_deCOase
description: Uroporphyrinogen decarboxylase (URO-D)

phrase: PCWIMRQAG
type: DOMAIN
name: Uroporphyrinogen_deCOase
description: Uroporphyrinogen decarboxylase (URO-D)

phrase: KNDLILRAAKGEKVERPPCWIMRQAGRYLPEYHEVKNNRDFFQTCRDAEIASEITIQPVRRYRGLIDAAIIFSDILVIPQAMGMRVEMLEGKGPHFPEPLRNPEDLQTVLDYKVDVLKELDWAFKAITMTRIKLDGEVPLFGFCGGPWTLMVYMTEGGGSRLFRFAKQWINMYPELSHKLLQKITDVAVEFLSQQVVAGAQILQVFESWGGELSSVDFDEFSLPYLRQIAERVPKRLQELGIMEQIPMIVFAKGSWYALDKLCCSGFDVVSLDWSWDPREAVKINKNRVTLQGNLDPGVMYGSKEVITKKVKQMIEAFGGGKSRYIVNFGHGTHPFMDPDVIKFFLEECH
type: DOMAIN
name: Uroporphyrinogen_deCOase
description: Uroporphyrinogen decarboxylase (URO-D)
Protein sequence:
MNFSCLGLSKICFLVSVIFCTFLLLFIPKTKTPWRPRTYPQPRPPPLFNATCGKQFALPGIEHAQQKLPTHTTDITHFEDPGNVEDWRAYILGRENPDEKHEGPTDNPGEHKSVLASSINSSKDALEFEDLFIAVKTTRKYHKTRLDLLLQTWISRAKQQTFIFTDGEDQDLRQRAGIQVINTNCSAMHTRQALCCKMAVEYDKFIESERKWFCHVDDDNYVNLFSLRHLLASFSHSQDVYLGRPSLDHPIEAIERVKSDGSASVRFWFATGGAGFCISRGLALKMSPWASMGNFITTAELVRLPDDCTIGYIIEGLLGVKMHHTPLFHSHLENLQRLPLQSVLKQVTLSYGGPDNKRNVVSVGGIFSLENDPTRFRTVHCLLYPDTHWCPPRKTR

Annotated regions:
phrase: LEFEDLFIAVKTTRKYHKTRLDLLLQTWISRAKQQTFIFTDGEDQDLRQRAGIQVINTNCSAMHTRQALCCKMAVEYDKFIESERKWFCHVDDDNYVNLFSLRHLLASFSHSQDVYLGRPSLDHPIEAIERVKSDGSASVRFWFATGGAGFCISRGLALKMSPWASMGNFITTAELVRLPDDCTIGYIIEGLLGVKMHHTPLFHSHLENLQRLPLQSVLKQVTLSYGGPDNKRNVVSVGGIFSLENDPT
type: DOMAIN
name: Fringe-like_glycosylTrfase
description: Fringe-like, glycosyltransferase domain
Protein sequence:
MPRPTLTSKLSLPHRLKHNNHGGSNGNGSSSTSNSVPASRSTSPKRQMSDPTRAGLVLRANVIKGRNLAAKDRSGTSDPYLVLTLGDTKQATPTINKSLNPVWNQTLDLPVADSQSVLLEVCCWDKDRFGKDYMGEFDVMLEDVFQNGNPTQEPKWFPLESRRTGKKKSVVTGEVCIQFSLIDTSSPSATPDQVMHKFMGFAQTSPSPEDEDDDALLRMESGEGDDQDNDQDNDQDNDEEEEESSDEVQDESKKAEKREKRRRKLRLAKLKRKAKQRAYEFSGKTEVAGVLFLEIVKITDLPPERNVTRTSFDMDPFVVTSLGKKTYRTKVVNHNLNPVFEEKLVFQVLKHETNYSLCFTIIDRDKFSGNDYIGAVNFPLEKPLSVAPDADPTTGLYRLPEPQDSPGTPGTSEARRSRFRLPMSRSSSAHSLSRLGKPSLKKENSQSSLSNLNYSNSNTLPPPPTSAPTTPGVNTDGNGALAPPMPMVNIDPTAVDDMDLKMYTLPIEMKNKDRWESKHSPVLYIRAKYLPYKALRQQFWRAMLKQYDADDSGLIDKVELTTMLDSLGSTLHESTINGFFERFSSENNGDELLTFDQVVICLEDRLQNTVAPDPSQSSWSHLTASSSDLLSETPGTMTPSATSGSRTPLNFEPTSTSIPILSQSSKGSQGEESGDTLHDDLADEKGEEHVIEIRECPICHQPRLNKKSDADIITHVATCASQDWRQVNNIVMAGFVTSSQAQRKWYSKVITKISYGGYKLGANSANIL

Annotated regions:
phrase: KRKAKQRAYEFSGKTEVAGVLFLEIVKITDLPPERNVTRTSFDMDPFVVTSLGKKTYRTKVVNHNLNPVFEEKLVFQVLKHETNYSLCFTIIDRDKFSGNDYIGAVNFPLEKPLSVAPDADPTTGL
type: DOMAIN
name: C2_dom
description: C2 domain

phrase: VLRANVIKGRNLAAKDRSGTSDPYLVLTLGDTKQATPTINKSLNPVWNQTLDLPVADSQSVLLEVCCWDKDRFGKDYMGEFDVMLEDVFQNGNPTQ
type: DOMAIN
name: C2_dom
description: C2 domain

phrase: VLFLEIVKITDLPPERNVTRTSFDMDPFVVTSLGKKTYRTKVVNHNLNPVFEEKLVFQVLKHETNYSLCFTIIDRDKFSGNDYIGAVNFPLEKPLSVAPDAD
type: DOMAIN
name: C2_dom
description: C2 domain

phrase: SRSTSPKRQMSDPTRAGLVLRANVIKGRNLAAKDRSGTSDPYLVLTLGDTKQATPTINKSLNPVWNQTLDLPVADSQSVLLEVCCWDKDRFGKDYMGEFDVMLEDVFQNGNPTQEPKW
type: DOMAIN
name: C2_dom
description: C2 domain

phrase: VLFLEIVKITDLPPERNVTRTSFDMDPFVVTSLGKKTYRTKVVNHNLNPVFEEKLVFQVLKHETNYSLCFTIIDRDKFSGNDYIGAVNFPLEKP
type: DOMAIN
name: C2_dom
description: C2 domain

phrase: LRANVIKGRNLAAKDRSGTSDPYLVLTLGDTKQATPTINKSLNPVWNQTLDLPVADSQSVLLEVCCWDKDRFGKDYMGEFDVMLEDVFQNGNPTQEPKWFP
type: DOMAIN
name: C2_dom
description: C2 domain

phrase: DADDSGLIDKVE
type: BINDING_SITE
name: EF_Hand_1_Ca_BS
description: EF-Hand 1, calcium-binding site

phrase: LRQQFWRAMLKQYDADDSGLIDKVELTTMLDSLGS
type: DOMAIN
name: EF_hand_dom
description: EF-hand domain
Protein sequence:
MSKILLGFMGAGKTTVGRLLDPNFHDMDELIVNQIGMSINDFFAQEGEEAFRKIETATLESLLANQAKIISPGGGIVVNPHNRDLLEKNPYNIYLRVDFDTLYKRIENDLAMQRPLYLNNTREEFKKIFEARLPIYEKIATHIIDVAGKTPEEIAEIIRCL

Annotated regions:
phrase: RKIETATLESLLANQAKIISPGGGI
type: CONSERVED_SITE
name: Shikimate_kinase_CS
description: Shikimate kinase, conserved site
Protein sequence:
MSSSLRFTVSPSLLGPHPHELTYQAEAIRIAHRMLHERTGPGAGFTGWLDLPERYDREEFRRIQEAAARIRGDSDVLVVIGIGGSYLGARATVEALGHAFHNLLPPERRGAPQIFFAGTDLSPRYLTELLDVLEDREVSLNVVSKSGTTTEPAIAFRLLRNWMERRYGKEGARRRIYATTDAARGALKQLADAEGYTRFVIPDDVGGRYSVLTAVGLLPIAAAGIDIDALMAGAAAAAAAYSDPDLERNPCYQYAAARNALYRKGMTTEVLVTYEPALKATAEWWKQLFGESEGKDGKGIFPAAAAFTTDLHSLGQYIQEGMRNLFETVVHVERPSVDIPLPPGDEGDGLGFLGGQTLHHVNHTAFLATRLAHTEGGVPNLTLTLPELTPYHYGYMLYFFMKACAISGYLLGVNPFDQPGVEAYKQNMYALLGKPGFEARRAEIEERL

Annotated regions:
phrase: TEVLVTYEPALKATAEWWKQLFGESEGKDGKGIFPAAAAFTTDLHSLGQYIQEGMRNLFETVVHVERPSVDIPLPPGDEGDGLGFLGGQTLHHVNHTAFLATRLAHTEGGVPNLTLTLPELTPYHYGYMLYFFMKACAISGYLLGVNPFDQPGVEAYKQNMYA
type: DOMAIN
name: SIS_PGI_2
description: Phosphoglucose isomerase, SIS domain 2

phrase: GYLLGVNPFDQPGVEAY
type: CONSERVED_SITE
name: Phosphoglucose_isomerase_CS
description: Phosphoglucose isomerase, conserved site

phrase: DDVGGRYSVLTAV
type: CONSERVED_SITE
name: Phosphoglucose_isomerase_CS
description: Phosphoglucose isomerase, conserved site

phrase: REEFRRIQEAAARIRGDSDVLVVIGIGGSYLGARATVEALGHAFHNLLPPERRGAPQIFFAGTDLSPRYLTELLDVLEDREVSLNVVSKSGTTTEPAIAFRLLRNWMERRYGKEGARRRIYATTDAARGALKQLADAEGYTRFVIPDDVGGRYSVLTAVGLLPIAA
type: DOMAIN
name: SIS_PGI_1
description: Phosphoglucose isomerase, SIS domain 1