nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
MGKKKDICSYTYEELAEEMRAAGEKAFRAKQIYQWLHVKLADSFEEMTNLSRALREKLDKEYQIARVELVERQISKADPTEKFLFELEDGNMVESVLMKYDYGNSVCISSQAGCRMGCRFCASTIGGLIRNLTTSEMLRQIYRIQKITGERVSNIVVMGTGEPLDNYDNFVRFVRMVSAPEGLNISQRNITASTCGIVPGILRLAEEGFQITLALSLHAGTQEKRKSLMPVANRYELSEVLEACDTYFEKTGRRITFEYSLVKDVNDTDEDAAELIRIAGHRNCHINLIPVNPVRERSYVRPSRQNALKFQNKLEKNGINVTIRRERGSDIDGACGQLRRRYAAAGKERADEILRAD

Annotated regions:
phrase: YDYGNSVCISSQAGCRMGCRFCASTIGGLIRNLTTSEMLRQIYRIQKITGERVSNIVVMGTGEPLDNYDNFVRFVRMVSAPEGLNISQRNITASTCGIVPGILRLAEEGFQITLALSLHAGTQEKRKSLMPVANRYELSEVLEACDTYFEKTGRRITFEYSLVKDVNDTDEDAAELIRIAGHRNCHINLIPVNPVRERSYVRPSRQNALKFQNKLEKNGINVTIRRERGS
type: DOMAIN
name: rSAM
description: Radical SAM

phrase: SSQAGCRMGCRFCASTIGGLIRNLTTSEMLRQIYRIQKITGERVSNIVVMGTGEPLDNYDNFVRFVRMVSAPEGLNISQRNITASTCGIVPGILRLAEEGFQITLALSLHAGTQEKRKSLMPVANRYELSEVLEACDTYFEKTGRRITFEYSLVKDVNDTDEDAAEL
type: DOMAIN
name: rSAM
description: Radical SAM

phrase: ICSYTYEELAEEMRAAGEKAFRAKQIYQWLHVKLADSFEEMTNLSRALREKLDKEYQ
type: DOMAIN
name: RlmN_N
description: Dual-specificity RNA methyltransferase RlmN, N-terminal domain
Protein sequence:
MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRCNTPGGFLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYKPPPSATDVSFHKENAVVTNVLAEQDLNKIVKEG

Annotated regions:
phrase: NANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPKVYYNCS
type: DOMAIN
name: Kazal_dom
description: Kazal domain

phrase: GNLIAPCNANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPKVYYNCSCI
type: DOMAIN
name: Kazal_dom
description: Kazal domain

phrase: FLLHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFCLLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNSTSCTSSTSSLSNYLYVFILGQLLLGAGGTPLYTLGTAFLDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDVTEDDPRWLGAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNADVKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFAATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEPFAGVSESYNGTGELGNLIAPCNANCNCSRSYYYPVCGDGVQYFSPCFAGCSNPVAHRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKCETHCAKLPIFLCIFFIVIIFTFMAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGIKGACWIYDNIKMAHMLVAISVTCKVITMFFNGFA
type: DOMAIN
name: MFS_dom
description: Major facilitator superfamily domain
Protein sequence:
MTKYKLEYIWLDATRPYQTLRGKTQIKEFDAFPTLEQLPLWGFDGSSTLQAEGRTSDCVLKPVTVYPDPVRTNGALVMCEVMMPDAETPHASNTRATVLDDEGAWFGFEQEYFFYKNGRPLGFPEQGYPAPQGPYYTGVGYKNVGDVARQIVEEHLDICLAAGINHEGINAEVAKGQWEFQIFGKGSKKAADEVCVARYLLVRLTEKYGIDVEFHCKPLGDTDWNGSGMHANFSTAYLREVGGQDYFEALMAAFEKNLHDHINVYGPDNHLRLTGKHETAPWDKFSYGVADRGASIRVPHSFVNNAYPGYLEDRRANSQGDPYQMLLSS

Annotated regions:
phrase: ASNTRATVLDDEGAWFGFEQEYFFYKNGRPLGFPEQGYPAPQGPYYTGVGYKNVGDVARQIVEEHLDICLAAGINHEGINAEVAKGQWEFQIFGKGSKKAADEVCVARYLLVRLTEKYGIDVEFHCKPLGDTDWNGSGMHANFSTAYLREVGGQDYFEALMAAFEKNLHDHINVYGPDNHLRLTGKHETAPWDKFSYGVADRGASIRVPHSFVNNAYPGYLEDRRANSQGDPYQMLLS
type: DOMAIN
name: Gln_synth_cat_dom
description: Glutamine synthetase, catalytic domain

phrase: KPLGDTDWNGSGMHANF
type: CONSERVED_SITE
name: Gln_synth_gly_rich_site
description: Glutamine synthetase, glycine-rich site

phrase: PHASNTRATVLDDEGAWFGFEQEYFFYKNGRPLGFPEQGYPAPQGPYYTGVGYKNVGDVARQIVEEHLDICLAAGINHEGINAEVAKGQWEFQIFGKGSKKAADEVCVARYLLVRLTEKYGIDVEFHCKPLGDTDWNGSGMHANFSTAYLREVGGQDYFEALMAAFEKNLHDHINVYGPDNHLRLTGKHETAPWDKFSYGVADRGASIRVPHSFVNNAYPGYLEDRRANSQGDPYQMLLS
type: DOMAIN
name: Gln_synth_cat_dom
description: Glutamine synthetase, catalytic domain

phrase: KLEYIWLDATRPYQTLRGKTQIKEFDAFPTLEQLPLWGFDGSSTLQAEGRTSDCVLKPVTVYPDPVRTNGALVMCEVMM
type: DOMAIN
name: Gln_synt_N
description: Glutamine synthetase, N-terminal domain

phrase: YKLEYIWLDATRPYQTLRGKTQIKEFDAFPTLEQLPLWGFDGSSTLQAEGRTSDCVLKPVTVYPDPVRTNGALVMCEVMMPD
type: DOMAIN
name: Gln_synt_N
description: Glutamine synthetase, N-terminal domain

phrase: FDGSSTLQAEGRTSDCV
type: CONSERVED_SITE
name: Gln_synth_N_conserv_site
description: Glutamine synthetase, N-terminal conserved site

phrase: WFGFEQEYFFYKNGRPLGFPEQGYPAPQGPYYTGVGYKNVGDVARQIVEEHLDICLAAGINHEGINAEVAKGQWEFQIFGKGSKKAADEVCVARYLLVRLTEKYGIDVEFHCKPLGDTDWNGSGMHANFSTAYLREVGGQDYFEALMAAFEKNLHDHINVYGPDNHLRLTGKHETAPWDKFSYGVADRGASIRVPHSFVNNAYPGYLEDRRANSQGDP
type: DOMAIN
name: Gln_synth_cat_dom
description: Glutamine synthetase, catalytic domain
Protein sequence:
MSNRTVFFISDGTGITAETFGNAILAQFEISPRHVRLPFIDTVDKAHQAIRHINHTGELEGKRPIVFTTLVNMDILAVLKAQCNGMLLDMFGIFVAPLESELGIKSNHRVGRFSDASKSKAYDERIEAINFSLAHDDGQSHRDLAGSDVILVGVSRSGKTPTTLYLAMQYGLKASNYPLIPEDFERRQLPPALVPHRKKIFGLTIAPERLSQIRNERRPNSTYSSLANCRNEIHEAEAMMRREGIRWLSTTTKSIEEIATTILQEIRPERLEY

Annotated regions:
Protein sequence:
MPPSAEFARSTSTNEAAPIRFDNTYARLPEAFYQRVEPATAAAPRLLRVNDALARQLRIDPQFLESPEGVAVLSGNVIAPGSEPIAQAYAGHQFGDFVPQLGDGRAILLGEVVDVAGKRYDLQLKGSGRTRFSRGGDGRAALGPVIREYIVSEAMAALGIPTTRSLAAVLTGENVMRERVLPGGVLTRVASSHLRVGTFQYFAARGDIENLRVLADYAIERHYPEARSAEDPYRAFYDAVVAALARLAARWMLVGFIHGVLNTDNTAIGGETIDYGPCAFMDAYHPDKVFSSIDQFGRYAFANQPAVIRWNLTRFAETLLPLMADGTDKAIEAANASIARFKDQYQDAYIRGFRQKLGLALEMEGDLELAADLLARMAENQADFTLTFRALCEAAADPKGNAGVRALFANPSAFDEWAARWRERLSLEERSAEARRTAMLAASPVFIPRNHRIEAAIQDAEAGHFDKFHELVEVLAHPYDDQPQFADYGKPPAPGEEVQQTFCGT

Annotated regions:
Protein sequence:
MAKSSLNVAVIGATGAVGDVFLRVAAERNFPFSSLKLLATARSAGKTLRYKDQEIVVEETSVEALKGADLVFCSATSAASREYAPIITKMGGVMIDDGSAFRMQANVPLVIPEVNGDDLEWHEGIISIPNCTTTPLAMALHAMRQVAPLRRVTVATYQATSGTGAAAVEELKSQLGAFGRGEPIPAASVYPHQIAMNVLPQVDVFGEDGYTAEEAKMRNETRKILHIDGLPFSATCARVPTVLGHAEAVHVEFEKDAPLDDIREALRNQPGLEIMDDPANSVYPMPLNTAGDDRAFVGRLRKDESTDHGIAFWCVTDNLRKGAATNAIQIAEELIRRGKI

Annotated regions:
phrase: MRQVAPLRRVTVATYQATSGTGAAAVEELKSQLGAFGRGEPIPAASVYPHQIAMNVLPQVDVFGEDGYTAEEAKMRNETRKILHIDGLPFSATCARVPTVLGHAEAVHVEFEKDAPLDDIREALRNQPGLEIMDDPANSVYPMPLNTAGDDRAFVGRLRKDESTDHGIAFWCVTDNLR
type: DOMAIN
name: Semialdhyde_DH_dimer_dom
description: Semialdehyde dehydrogenase, dimerisation domain

phrase: NVAVIGATGAVGDVFLRVAAERNFPFSSLKLLATARSAGKTLRYKDQEIVVEETSVEALKGADLVFCSATSAASREYAPIITKMGGVMIDDGSAFRMQANVPLVIPEVNGDDLEW
type: DOMAIN
name: Semialdehyde_DH_NAD-bd
description: Semialdehyde dehydrogenase, NAD-binding

phrase: NVAVIGATGAVGDVFLRVAAERNFPFSSLKLLATARSAGKTLRYKDQEIVVEETSVEALKGADLVFCSATSAASREYAPIITKMGGVMIDDGSAFRMQANVPLVIPEVNGDDL
type: DOMAIN
name: Semialdehyde_DH_NAD-bd
description: Semialdehyde dehydrogenase, NAD-binding
Protein sequence:
MRRNSERPVRITEVCLRDGSHVMKHQFTEEQVRFVTRALDEAGMHYIEVSHGDGLGGSTLQYGKSLVNEMKLIEAAVDECKQAQIAVLLIPGIGTIHELKQAANIGAKLVRVATHVTEADVSAQHIQFARELGMEVCGFLMMAHSASVEKLVEQGKLMESYGAEAVYVTDSAGALLPHEVRERIRALRQSLNIEIGFHGHNNLSVAVANTITAIEEGATRIDGSVRCLGAGAGNAQTEVLLAVLDRMGYKLDIDLYKMMDVAEEVVAPLLPVPQEIQKGSLVMGYAGVYSSFLLHAERAAQRFNVDARDILIELGKRKVVGGQEDMILDVAAELAKIKMEV

Annotated regions:
phrase: VRITEVCLRDGSHVMKHQFTEEQVRFVTRALDEAGMHYIEVSHGDGLGGSTLQYGKSLVNEMKLIEAAVDECKQAQIAVLLIPGIGTIHELKQAANIGAKLVRVATHVTEADVSAQHIQFARELGMEVCGFLMMAHSASVEKLVEQGKLMESYGAEAVYVTDSAGALLPHEVRERIRALRQSLNIEIGFHGHNNLSVAVANTITAIEEGATRIDGSVRCLGAGAGNAQTEVLLAVLDRMGYKLDIDLYKMMDVAEEVVAPL
type: DOMAIN
name: DRE_TIM_HOA
description: 4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain

phrase: VRITEVCLRDGSHVMKHQFTEEQVRFVTRALDEAGMHYIEVSHGDGLGGSTLQYGKSLVNEMKLIEAAVDECKQAQIAVLLIPGIGTIHELKQAANIGAKLVRVATHVTEADVSAQHIQFARELGMEVCGFLMMAHSASVEKLVEQGKLMESYGAEAVYVTDSAGALLPHEVRERIRALRQSLNIEIGFHGHNNLSVAVANTITAIEEGATRIDGSVRCLGAGAGNAQTEVLLAVLDRMGYKLDIDLYKMMDVAEE
type: DOMAIN
name: PYR_CT
description: Pyruvate carboxyltransferase

phrase: VRITEVCLRDGSHVMKHQFTEEQVRFVTRALDEAGMHYIEVSHGDGLGGSTLQYGKSLVNEMKLIEAAVDECKQAQIAVLLIPGIGTIHELKQAANIGAKLVRVATHVTEADVSAQHIQFARELGMEVCGFLMMAHSASVEKLVEQGKLMESYGAEAVYVTDSAGALLPHEVRERIRALRQSLNIEIGFHGHNNLSVAVANTITAIEEGATRIDGSVRCLGAGAGNAQTEVLLAVLDRMGYKLDIDLYKM
type: DOMAIN
name: PYR_CT
description: Pyruvate carboxyltransferase

phrase: EIQKGSLVMGYAGVYSSFLLHAERAAQRFNVDARDILIELGKRKVVGGQEDMILDVAAELA
type: DOMAIN
name: DmpG_comm
description: DmpG-like communication
Protein sequence:
MSLLTEVETYVLSIIPSGPLKAEIAQKLEDVFAGKNADLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYKKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMATITNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVANQARQMVQAMRTIGTHPNSSAGLRDNLLENLQAYQKRMGVQMQRFK

Annotated regions:
phrase: QHRSHRQMATITNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVANQARQMVQAMRTIGTHPNSSAGLRDNLLENLQAYQKRMGVQMQRF
type: DOMAIN
name: Flu_matrix_M1_C
description: Influenza matrix M1, C-terminal

phrase: SLLTEVETYVLSIIPSGPLKAEIAQKLEDVFAGKNADLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYKKLKREITFHGAKEVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIAD
type: DOMAIN
name: Flu_matrix_M1_N
description: Influenza matrix M1, N-terminal

phrase: QHRSHRQMATITNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVANQARQMVQAMRTIGTHPNSSAGLRDNLLENLQAYQKRMGVQMQRF
type: DOMAIN
name: Flu_matrix_M1_C
description: Influenza matrix M1, C-terminal
Protein sequence:
MNNKKTATNRKGMIPNRLNKFSIRKYSVGTASILVGTTLIFGLSGHEAKAAEHTNGELNQSKNETTAPSENKTTKKVDSRQLKDNTQTATADQPKVTMSDSATVKETSSNMQSPQNATANQSTTKTSNVTTNDKSSTTYSNETDKSNLTQAKDVSTTPKTTTIKPRTLNRMAVNTVAAPQQGTNVNDKVHFSNIDIAIDKGHVNQTTGKTEFWATSSDVLKLKANYTIDDSVKEGDTFTFKYGQYFRPGSVRLPSQTQNLYNAQGNIIAKGIYDSTTNTTTYTFTNYVDQYTNVRGSFEQVAFAKRKNATTDKTAYKMEVTLGNDTYSEEIIVDYGNKKAQPLISSTNYINNEDLSRNMTAYVNQPKNTYTKQTFVTNLTGYKFNPNAKNFKIYEVTDQNQFVDSFTPDTSKLKDVTDQFDVIYSNDNKTATVDLMKGQTSSNKQYIIQQVAYPDNSSTDNGKIDYTLDTDKTKYSWSNSYSNVNGSSTANGDQKKYNLGDYVWEDTNKDGKQDANEKGIKGVYVILKDSNGKELDRTTTDENGKYQFTGLSNGTYSVEFSTPAGYTPTTANVGTDDAVDSDGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKGVKVTLQNEKGEVIGTTETDENGKYRFDNLDSGKYKVIFEKPAGLTQTGTNTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSNSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDNDSDSDSDSDSDAGKHTPAKPMSTVKDQHKTAKALPETGSENNNSNNGTLFGGLFAALGSLLLFGRRKKQNK

Annotated regions:
phrase: QHKTAKALPETGSENNNSNNGTLFGGLFAALGSLLLFGRRKKQN
type: DOMAIN
name: LPXTG_anchor
description: LPXTG cell wall anchor domain

phrase: LPETGSENNNSNNGTLFGGLFAALGSLLLFGRRKKQN
type: DOMAIN
name: LPXTG_anchor
description: LPXTG cell wall anchor domain

phrase: SLGDYVWYDSNKDGKQDSTEKGIKGVKVTLQNEKGEVIGTTETDENGKYRFDNLDSGKYKVIFEKPAGLTQTGTNTTEDDKDADGGEVDVTITDHDDFTLDNG
type: DOMAIN
name: Sdr_B
description: SD-repeat containing protein, B domain

phrase: NLGDYVWEDTNKDGKQDANEKGIKGVYVILKDSNGKELDRTTTDENGKYQFTGLSNGTYSVEFSTPAGYTPTTANVGTDDAVDSDGLTTTGVIKDADNMTLDS
type: DOMAIN
name: Sdr_B
description: SD-repeat containing protein, B domain

phrase: KGMIPNRLNKFSIRKYSVGTASILVGTTLIFGLSGHEAKAA
type: DOMAIN
name: YSIRK_signal_dom
description: YSIRK Gram-positive signal peptide

phrase: NKKAQPLISSTNYINNEDLSRNMTAYVNQPKNTYTKQTFVTNLTGYKFNPNAKNFKIYEVTDQNQFVDSFTPDTSKLKDVTDQFDVIYSNDNKTATVDLMKGQTSSNKQYIIQQVAYPDNSSTDNGKIDYTLDTDKTKYSWSNSYSNV
type: DOMAIN
name: Adhesin_Fg-bd_dom_2
description: Fibrinogen-binding domain 2

phrase: NRLNKFSIRKYSVGTASILVGTTLI
type: DOMAIN
name: YSIRK_signal_dom
description: YSIRK Gram-positive signal peptide

phrase: SSDVLKLKANYTIDDSVKEGDTFTFKYGQYFRPGSVRLPSQTQNLYNAQGNIIAKGIYDSTTNTTTYTFTNYVDQYTNVRGSFEQVAFAKRKNATTD
type: DOMAIN
name: SDR_Ig
description: SDR-like Ig domain
Protein sequence:
MTPQLSSSVASKLVTLKLKPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGIDYHFVTKEEFQKLVAEEKFVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPIDAQYVFLAPPSIEQLEVRLRGRGTENESAILQRLERARAEIEYSEKPGNFDALIVNDDVEKAYKQLEAICLSD

Annotated regions:
phrase: KLKPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGIDYHFVTKEEFQKLVAEEKFVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPIDAQYVFLAPPSIEQLEVRLRGRGTENESAILQRLERARAEIEYSEKPGNFDALIVNDDVEKAYKQLEAICLS
type: DOMAIN
name: GK/Ca_channel_bsu
description: Guanylate kinase/L-type calcium channel beta subunit

phrase: KPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGIDYHFVTKEEFQKLVAEEKFVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPIDAQYVFLAPPSIEQLEVRLRGRGTENESAILQRLERARAEIEYSEKPGNFDALIVNDDVEKAYKQLEA
type: DOMAIN
name: GK/Ca_channel_bsu
description: Guanylate kinase/L-type calcium channel beta subunit

phrase: TTRTPRAGEKDGIDYHF
type: CONSERVED_SITE
name: Guanylate_kinase_CS
description: Guanylate kinase, conserved site

phrase: LKPVVVFGPSGVGKSTLLKRLLKDHGDKLGFSVSHTTRTPRAGEKDGIDYHFVTKEEFQKLVAEEKFVEWAVFSGNMYGTSIMAIQELEAVNKKAILDIDLQGVLQVKASPIDAQYVFLAPPSIEQLEVRLRGRGTENESAILQRLERARAEIEYSEKPGNFDALIVNDDVEKAYKQLEAIC
type: DOMAIN
name: Guanylate_kin-like_dom
description: Guanylate kinase-like domain
Protein sequence:
MYKFNTIQEAIEDIKNGKMVIVVDDEDRENEGDLVMAAQKVTPESINFMTKYARGLICMPIIEERLKELDLPQMVSNNTDPHETAFTVSIDHIDTTTGISASERCLTILKAIDENCTFNDFKRPGHIFPLRYTPGGVLKRAGHTEAAVDLSKLANLYPAGVICEIMNDDGTMARVPELIEFSKIHNLKIITIADLIKYRRKNECLVQRVACANMPTRYGNFKAFGYINKLNNEHHIALVKGDISTDEPVLVRVHSECLTGDAFGSLRCDCGDQFAYAMKKIENEGRGILLYMRQEGRGIGLINKLKAYSLQDKGLDTVDANLALGFPDDMRDYGIGAQILLDLGVKKIKLMTNNPKKLSGLSGYGLEVVDRVAIQINNSKESIDYLKTKKQKLGHMLEFKEE

Annotated regions:
phrase: RVACANMPTRYGNFKAFGYINKLNNEHHIALVKGDISTDEPVLVRVHSECLTGDAFGSLRCDCGDQFAYAMKKIENEGRGILLYMRQEGRGIGLINKLKAYSLQDKGLDTVDANLALGFPDDMRDYGIGAQILLDLGVKKIKLMTNNPKKLSGLSGYGLEVVDR
type: DOMAIN
name: GTP_cyclohydro_II
description: GTP cyclohydrolase II
Protein sequence:
MLETLKKEVLAANLKLQEHQLVTFTWGNVSGIDREKERIVIKPSGVEYSDLTADDLVVLNLDGEVVEGSLKPSSDTPTHVYLYKAFPNIGGIVHTHSQWATSWAQSGRDIPPLGTTHADYFDSAIPCTREMYDEEIIHDYELNTGKVIAETFQHHNYEQVPGVLVNNHGPFCWGTDALNAIHNAVVLETVAEMAYHSIMLNKDVTPINTVLHEKHFYRKHGANAYYGQS

Annotated regions:
phrase: EVLAANLKLQEHQLVTFTWGNVSGIDREKERIVIKPSGVEYSDLTADDLVVLNLDGEVVEGSLKPSSDTPTHVYLYKAFPNIGGIVHTHSQWATSWAQSGRDIPPLGTTHADYFDSAIPCTREMYDEEIIHDYELNTGKVIAETFQHHNYEQVPGVLVNNHGPFCWGTDALNAIHNAVVLETVAEMA
type: DOMAIN
name: Aldolase_II/adducin_N
description: Class II aldolase/adducin N-terminal

phrase: KEVLAANLKLQEHQLVTFTWGNVSGIDREKERIVIKPSGVEYSDLTADDLVVLNLDGEVVEGSLKPSSDTPTHVYLYKAFPNIGGIVHTHSQWATSWAQSGRDIPPLGTTHADYFDSAIPCTREMYDEEIIHDYELNTGKVIAETFQHHNYEQVPGVLVNNHGPFCWGTDALNAIHNAVVLETVAEMA
type: DOMAIN
name: Aldolase_II/adducin_N
description: Class II aldolase/adducin N-terminal
Protein sequence:
MEAAVAAPRPRLLLLVLAAAAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGIKM

Annotated regions:
phrase: IAHRDLKSKNIL
type: ACTIVE_SITE
name: Ser/Thr_kinase_AS
description: Serine/threonine-protein kinase, active site

phrase: IGKGRFGEVWRGKWRGEEVAV
type: BINDING_SITE
name: Protein_kinase_ATP_BS
description: Protein kinase, ATP binding site

phrase: TTLKDLIYDMTTSGSGSGLPLLVQRTIART
type: DOMAIN
name: GS_dom
description: GS domain

phrase: TTLKDLIYDMTTSGSGSGLPLLVQRTIAR
type: DOMAIN
name: GS_dom
description: GS domain

phrase: IVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQ
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: IVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKI
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: TLKDLIYDMTTSGSGSGLPLLVQRTIA
type: DOMAIN
name: GS_dom
description: GS domain

phrase: LQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRI
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: LQCFCHLCTKDNFTCVTDGLCFVSVTETTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNK
type: DOMAIN
name: Activin_recp
description: Activin types I and II receptor domain
Protein sequence:
MKAPVRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVTLQLLEIPQAQEALQGTVMELEDCAFPLVDGIIATDSAEEAFRDADYVLLVGAKPRGPGMERKDLLEANAAIFSAQGQALNAVAKRDVKVLAVGNPANTNALITQRNAPDLDPRNFTAMTRLDHNRALAQLSNKVGCHSTEIRGLAVWGNHSATQYPDISHCTIQGRPAADQVEHAWVKDTFIPTVQQRGAAIIKARGASSAASAASAAIDHMRDWALGTPEGEWTSMAVPSDGSYGIEAGLIYSFPVTCRGGDYKIVSGLSVDDFSRARMDQTAAELAEERDAVAHLLP

Annotated regions:
phrase: MTRLDHNRALAQ
type: ACTIVE_SITE
name: Malate_DH_AS
description: Malate dehydrogenase, active site

phrase: TRLDHNRALAQLSNKVGCHSTEIRGLAVWGNHSATQYPDISHCTIQGRPAADQVEHAWVKDTFIPTVQQRGAAIIKARGASSAASAASAAIDHMRDWALGTPEGEWTSMAVPSDGSYGIEAGLIYSFPVTCRGGDYKIVSGLSVDDFSRARMDQTAAELAEERDAV
type: DOMAIN
name: Lactate/malate_DH_C
description: Lactate/malate dehydrogenase, C-terminal

phrase: VRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVTLQLLEIPQAQEALQGTVMELEDCAFPLVDGIIATDSAEEAFRDADYVLLVGAKPRGPGMERKDLLEANAAIFSAQGQALNAVAKRDVKVLAVGNPANTNALITQRNAPDLDPRN
type: DOMAIN
name: Lactate/malate_DH_N
description: Lactate/malate dehydrogenase, N-terminal
Protein sequence:
MPPKEAPKKWKAPKGPKPTHRKNKNKLELGRAIKYARQKENAIEYLPDGEMRFTTDKHEANWVKLRSVTQESALDEFLSTAALADKDFTADRHSNVKIIRMDSGNDSATSQGFSMTNEQRGNLNAKQRALAKDLIVPRRPEWNEGMSKFQLDRQEKEAFLEWRRKLAHLQESNEDLLLTPFERNIEVWKQLWRVVERSDLVVQIVDARNPLLFRSVDLERYVKESDDRKANLLLVNKADLLTKKQRIAWAKYFISKNISFTFYSALRANQLLEKQKEMGEDYREQDFEEADKEGFDADEKVMEKVKILSIDQLEELFLSKAPNEPLLPPLPGQPPLINIGLVGYPNVGKSSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGLVFPNFAYNKGELVCNGVLPIDQLRDYIGPAGLVAERIPKYYIEAIYGIHIQTKSRDEGGNGDIPTAQELLVAYARARGYMTQGYGSADEPRASRYILKDYVNGKLLYVNPPPHLEDDTPYTREECEEFNKDLYVFDRLPDTRKEQVQNAAKAKGIDIVDLARDLNQLTFSAHTGGDTQKEAKSVTHGGKQAALYNAAEDLDRDFFKMNNVEGRLSTPFHKVQNSSAGKRHNKKNKSKNAKSKVFSIENN

Annotated regions:
phrase: WKQLWRVVERSDLVVQIVDARNPLLFRSVDLERYVKESDDRKANLLLVNKADLLTKKQRIAWAKYFISKNISFTFYSALRANQLLEKQKEMGEDYREQDFEEADKEGFDADEKVMEKVKILSIDQLEELFLSKAPNEPLLPPLPGQPPLINIGLVGYPNVGKSSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGLVF
type: DOMAIN
name: G_CP_dom
description: Circularly permuted (CP)-type guanine nucleotide-binding (G) domain

phrase: IGLVGYPNVGKSSTINSLVGAKKVSVSSTPGKTKHFQTIKLSDSVMLCDCPGL
type: DOMAIN
name: GTP-bd
description: GTP binding domain
Protein sequence:
MERHPASASSRQELGRLLEAVLTSRGQANAVFDILAVLQSEEPEEIEEGVRTCSRLFGTLLEREELFVGSLPSEDTALAGSQGATYKYKVWIRHRYHSCCNRLEELLAHPTFQVKELALKTLMKFVQLEGAKPLEKPQWESHYLFPRTLFRAVVGGLLTPEDDHSLLISHFCEYLEYDDIRYHTMQVATSIMARATSQQPEVSLTLWNNAFTLLSAVSLPLQECELTNFYVKHAQTSDKWKVVHLKEHKKAFQEMWLGFLKHKLPLSLYKKVLVAMHDSILPHLAQPTLMIDFLTSACDVGGAISLLALNGLFILIHKHNLEYPDFYQKLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGPELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSKAASVINQVLSVPEVSIAPLLELTAYEIFEQDLKKKMPESVPLEFIPAKGLLGRQDDLCTQFFCLS

Annotated regions:
phrase: SLLALNGLFILIHKHNLEYPDFYQKLYGLLDPSIFHVKYRARFFHLADLFLSSSHLPAYLVAAFAKRLARLALTAPPEALLMVLPLICNLLRRHPACRVMVHRPQGPELDADPYDPTEKDPARSRALESCLWELQTLQQHYHPEVSKA
type: DOMAIN
name: CCAAT-binding_factor
description: CCAAT-binding factor
Protein sequence:
MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS

Annotated regions:
phrase: NDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRR
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: IQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLL
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: EVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRR
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: NIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVF
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: GPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPA
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: EGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQ
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: AGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARR
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: MVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQ
type: DOMAIN
name: PDZ
description: PDZ domain

phrase: MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQ
type: DOMAIN
name: Par3/HAL_N
description: Par3/HAL, N-terminal
Protein sequence:
MPESSRDKGNAAISGNRSVLSIASPTKLNILSSDWSRNQGKVSKNSLKRSSSLNIRNSKRPSLQASANSIYSRPKITIGAPPLIRRDSSFFKDEFDAKKDKATFSAYSSRSYPTIGSESVVSQTSLSQPTTSREVDEQFTVAADRYIPILQGASQNKVDPETLHEALPPPNASPISHLRAQTKIVFKQNVAEACGLDMNKRILQYMPEPPKCSSLRQKSYIMKKRTHYSYQQEQKIPDLIKLRKINTNPERILDAPGFQDDFYLNLLSWSKKNVLAIALDTALYLWNATTGDVSLLTDFENTTICSVTWSDDDCHISIGKEDGNTEIWDVETMSLIRTMRSGLGVRIGSLSWLDTLIATGSRSGEIQINDVRIKQHIVSTWAEHTGEVCGLSYKSDGLQLASGGNDNTVMIWDTRTSLPQFSKKTHTAAVKALSWCPYSPNILASGGGQTDKHIHFWNSITGARVGSINTGSQVSSLHWGQSHTSTNGGMMNKEIVATGGNPENAISVYNYETKFKVAEVVHAHEARICCSQLSPDGTTLATVGGDENLKFYKIFDPRCTGRSREDGLMDGMLGLIGKEGCRTNDKENRSKNSSEIHTRRPSSTSQYLIR

Annotated regions:
phrase: LDAPGFQDDFYLNLLSWSKKNVLAIALDTALYLWNATTGDVSLLTDFENTTICSVTWSDDDCHISIGKEDGNTEIWDVETMSLIRTMRSGLGVRIGSLSWLDTLIATGSRSGEIQINDVRIKQHIVSTWAEHTGEVCGLSYKSDGLQLASGGNDNTVMIWDTRTSLPQFSKKTHTAAVKALSWCPYSPNILASGGGQTDKHIHFWNSITGARVGSINTGSQVSSLHWGQSHTSTNGGMMNKEIVATGGNPENAISVYNYETKFKVAEVVHAHEARICCSQLSPDGTTLATVGGDENLKF
type: DOMAIN
name: WD40_CDC20-Fz
description: CDC20/Fizzy, WD40 domain

phrase: WAEHTGEVCGLSYKSDGLQLASGGNDNTVMIWDTR
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: TDFENTTICSVTWSDDDCHISIGKEDGNTEIWDVETMSLIR
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: LASGGNDNTVMIWD
type: CONSERVED_SITE
name: WD40_repeat_CS
description: WD40 repeat, conserved site

phrase: TMSLIRTMRSGLGVRIGSLSWLDTLIATGSRSGEIQIN
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: KFKVAEVVHAHEARICCSQLSPDGTTLATVGGDENLKFY
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: KQHIVSTWAEHTGEVCGLSYKSDGLQLASGGNDNTVMIW
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: TSLPQFSKKTHTAAVKALSWCPYSPNILASGGGQTDKHIHFW
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: TGARVGSINTGSQVSSLHWGQSHTSTNGGMMNKEIVATGGNPENAISVY
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: TTGDVSLLTDFENTTICSVTWSDDDCHISIGKEDGNTEIW
type: REPEAT
name: WD40_rpt
description: WD40 repeat

phrase: ISIGKEDGNTEIWD
type: CONSERVED_SITE
name: WD40_repeat_CS
description: WD40 repeat, conserved site