Protein sequence:
MSRKALGSRLSSAHKLQRNWNDWQPRSDSLSASQDGVKCSVSRDRGSEVLFEILPSDRPGTPPLHNDAFTATDALEEGGGYDADGGLSENAYGWKSLGQELRINDVTTDITTFQHGNRALATKDMRKSQDRPLAHSEESRLANLLRRASREDDRERRLATMKQMKEFIVHSENKVVLVKQLDSILSTLNDILNESSKLLQELRQEAAWCLGLLCAALSYEAERIFKWMFLKFSVSTKDEVKLLYLVAVHKALETAGEKKAFSAVMQLVMSNLQSILENLDTPELLCQSVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKHSLTQQVSGWLQSLEQFWVADLAFSTTLLGQFLEDMEAYAEDLSHVVSGESGDEDIPPPTVSLPKLAALLRVFSTVVHSIGERFNPIRGPPITEAYVTDVLNRVLACVTTAKQVFFSEAVLTAGNECVCVLLVSIDLGGQLIDAVISYGLDQLNCCQNCGPEYSLSVLTLLTLVVDQINTKLPASFVEKLLAPKSHLLELRFHREREVMAAAHGVYHAVLSLKNIPILEAAYKLVLGEMGCALNSLLSPLGLPDACPHIQHPAFSQLNFSPERAEFVLIFNLSALTTIGNTKNSLIGMWALSPTVFALLSQNLVIVHSDLAVHHPAVQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKRHFSTLLNLLGMLLSKDHLNPEARRLLLTWSLEVALMMKKSETYAPLFSLPSFLKFCKGLLANSLNEDTTICLQACNSLQVLSSSLTMELLQRCVDVCRVQLVHSAVRVRQAFGKLLRSVPMHVALSAHSHSEIKEISLAIRRHMSKVPSNTFHPQDFSDLIGFILYGTVHRGGKEPWLERLYHSCQRLEKKDSAMVPRALLKTEAVLWQWAVWEAAQFTVLSKLRTPLGRAQDTFQTIEGMIRSLAAHSLNTEQELSQWSGGESDEGHHTNQLRLALLLQFLENLEKLMYNAYEGCASALTAPPKGIRTFFYTNRQTCQDWLTRIRLALMRVGLLSGQPAVTVRHGFDLLTEIKNSSTQGPEMEVPVTMLVEALCELRCPEAIQGLAAWSLANTGKSMGWLSSVALQAEGKFEKAALEYQEQLCAVTGMDCSIKVFDRSLLKLTGTNTSSPKHTSSGEGRKTVLLKSSECSPEVLNFLANKACECYVALSDWESVQEWQASMMNLKKNSSSSSVNLKTDFNYIRSMSRFEEGDFTECRAQLELLPGDDYGLLNSTTKDKIDLKRLLPAVLSPDPSELQKAIEVQLLRSAVGAISATNHEQDQKVASSDTLVKYLKQTGRICLGPLRLSTLTLSDSLPTLSTLQLHCANSLENSLCNQHPEDCLIPLFSEALTTCKQQDVQPWLHALRYTTFQREFFQKLKGSSSPVDSHLMELCLTAVKFARKQGNIALATRLLSLCSKPAMSDTEGQDLVQSFRQLSLEGTVGEKWGPELEIEKAKVLFAAGQSVSAMEMLSSCALSYCHSGKCELAACRSVLTLCKWLLADWKDLTPQLKMVVKKNSGSTSLSTLSKNISGLLELPLEDQGMPHITTETTVSVGVGEPDFVLGQLYQLSTTQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVPLLLGEKKEIEELLPAGTSDEDKETIFGILGQAMCRPAGIQDEDMALQNEEDDEDDMVDVIGRQLLGACPWLSDVEDTVTDGLIGVWRRVVDRIFSLYRVSCRAYFTFLKLNAGQVPIDEDDPKLLLNNQNSKQSSDDVIVMATLRLLRLLVKHAGELREGLEHGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPHLILYPAIVGSISLGGEAQTAGNKLPSSLPTLLGNMQGEGLCGGESETGSGPTSQESSRGEEMVMYSSEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVGELRRVTLLWDELWLGVLQQQHMHVLRRIQQLEDEVKRVQNNNTLRKDEKVAIMREKHSALMKPVVFALDHVRSITAAPAETPHEEWFQETYGDAIHNALERLRSPLNPANPASSWVPFKQIMLSLQQRAQKRASYLLRLDEISPRLTAMANTEMALPGEVSATDAVTIQSVGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVVQAQKAQDSFQQPQNLPMVPRPSELYYSKISPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAENKQSKREMERDITRSLFSSRVAEIKVNWFKNRDEMTGVLPQLEEAVDEYLNLQEQLTQVEKVQGKLLEELEFLEGADTRADHPIHSLEHRYSEHTQLQSRQRTVQDAIQGKLSDLDQWISQYQAAFASLEATQLASLLQEISSPIDLGPPSYVPATSFLQNAGQAHLISQCEALEAEVSALLQQRRSQLRGCLEHLHSYATVALLYPRAVLHRHRAHTWKQWMEELVCDMTVDHCQTIYHQYEMQFAPQPPPATCQFLSSIEMALQHHAAETNTRLLRQVERLKAEGASVPVCEEQLQEIERCIKVFLHEDAELGSFSLAGIIVSALCSLTRRNLVMEGAAASAGEQLVELTSRDGAWFLEELCSMSGNITCLVQLLQQCQLLSHDLDIPSPAETSQVVYLTNGVYTCLQELNTNFRQIIFPEALRCMLKGENTLETMLAELDALIDQCADGVSLQGLGEILMAHIRNASMGLEEDPDDHYLDVTRVLRAQYSELIQPRSMESSVQETPKMSAGQMLLVAFDGMFAQLETAFGLLIDKLNSMDVPAAWRKVDVIRESRATQAHFFDNVQTRQVLEEIFFLKRLQTIRDFFRLCGSFAQTLSGTCPTPTDDPPPSNGPVPIVKPLYRGSTVVSEDQMTRPIKAFTADFVRQMLMGLPTQALGLAICSSLSALGMDLIAQVEAKDFGAEGKVSLDDLCKKAVEQGVQAGRLSQLLLNRATVLASSYDTAWKKLDLVRRLEVSIEACKVSLQRNQLHIAMFQWQHEDILGARTQPMTVSPPPRSIILSNMKKKLYKLSQDDASIGSVQEKLASLEGSIEQRLKWAGGANPALAPVLQDFEATIAERRALVIKESQRANQVTFLCSTILNFEGLRTRTPEALNMDAALFELVKRCQATCSYAAQFNTSVSSLELQLLHRLSPAMDMSIGGPEWLVYAQNHLTQEMSSQRAMQEEREQQLESVTETLQLLVDSIKGTLSNHNRQLADVKHLLRAMAKDEENALAEGEEVTYDGSVRQFLSEYKAWQDNVQIVLFTVVQATGQPRSQEQIELLQEIPATLKELKVQSHSIYNGLVGFASPLVTERGSDCISPTSTVQTSFAAAVRCSGVKTQPDSMSQNARKALPRNFGTPADTPPSTLMINSKGLAPSPKRAVRDPKTGRAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVTEQVDYVIKEATNVDNLAQLYEGWTAWV

Annotated regions:
phrase: RRMSVTEQVDYVIKEATNVDNLAQLYEGWTAW
type: DOMAIN
name: FATC_dom
description: FATC domain

phrase: IQSVGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVVQAQKAQDSFQQPQNLPMVPRPSELYYSKISPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWT
type: DOMAIN
name: SMG1_PIKKc
description: SMG1, PIKK catalytic domain

phrase: YCHSGKCELAACRSVLTLCKWLLADWKDLTPQLKMVVKKNSGSTSLSTLSKNISGLLELPLEDQGMPHITTETTVSVGVGEPDFVLGQLYQLSTTQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVPLLLGEKKEIEELLPAGTSDEDKETIFGILGQAMCRPAGIQDEDMALQNEEDDEDDMVDVIGRQLLGACPWLSDVEDTVTDGLIGVWRRVVDRIFSLYRVSCRAYFTFLKLNAGQVPIDEDDPKLLLNNQNSKQSSDDVIVMATLRLLRLLVKHAGELREGLEHGLASTPTAPWRGIIPQLFSRLNHPEAYIRQSICSLLCRVAQDSPHLILYPAIVGSI
type: DOMAIN
name: PIK_FAT
description: PIK-related kinase

phrase: MSVTEQVDYVIKEATNVDNLAQLYEGWTA
type: DOMAIN
name: FATC_dom
description: FATC domain

phrase: VGNTITILPTKTKPKKLYFLGSDGRNYPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVVQAQKAQDSFQQPQNLPMVPRPSELYYSKISPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAENKQSKREMERDITRSL
type: DOMAIN
name: PI3/4_kinase_cat_dom
description: Phosphatidylinositol 3-/4-kinase, catalytic domain

phrase: SDSLSASQDGVKCSVSRDRGSEVLFEILPSDRPGTPPLHNDAFTATDALEEGGGYDADGGLSENAYGWKSLGQELRINDVTTDITTFQHGNRALATKDMRKSQDR
type: DOMAIN
name: SMG1_N
description: Serine/threonine-protein kinase SMG1, N-terminal

phrase: YPYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVVQAQKAQDSFQQPQNLPMVPRPSELYYSKISPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDW
type: DOMAIN
name: PI3/4_kinase_cat_dom
description: Phosphatidylinositol 3-/4-kinase, catalytic domain

phrase: RRMSVTEQVDYVIKEATNVDNLAQLYEGWTAW
type: DOMAIN
name: FATC_dom
description: FATC domain

phrase: PYLFKGLEDLHLDERIMQFLSIVNTMFTKVNQQESPRFQARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAVVQAQKAQDSFQQPQNLPMVPRPSELYYSKISPALKAVGLSLDVSRRDWPLSVMRDVLRELMEATPPNLLAKELWCSCTTPSEWWSVTQTYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTHNIETALGVTGVEGIFRLSCEQVVQIMRRGRETLLTLLEAFVYDPLVDWTAGGEVGFAGAVYGGGGQQAENKQSKREMERDITRSLFSSRVAEIKVNWFKNRDEMTGVLPQLEEAVDEYLN
type: DOMAIN
name: PI3/4_kinase_cat_dom
description: Phosphatidylinositol 3-/4-kinase, catalytic domain

phrase: STAVMSMVGYIIGLGDRHLD
type: CONSERVED_SITE
name: PI3/4_kinase_CS
description: Phosphatidylinositol 3/4-kinase, conserved site