nwliu/Molinst-SwissProtCLAP huggingface dataset:
Protein sequence:
MSSQSHIPYAVRASRHSNPLARQLFQIAEEKKSNVVVSADVTTSKELLDLADRLGPYITVLKTHIDILTDLSPTTLTSLKSLASKHRFLLFEDRKFVDIGSTVQKQYHGGSLRISEWAHIVNCAMLAGPGIVDALAQTASTPEFRSVYANEVEGGRALLILAEMTSKGSMATGAYTQLSVEAARRHRAFVLGFVATRALNDVLPVSTVDGDEEDFVVFTTGVSLSASGDALGQQYQTPTSAVERGADFIISGRGIYAAEDPLEAVLRYREEGWKAYLERVKGWKA

Annotated regions:
phrase: LFEDRKFVDIGST
type: ACTIVE_SITE
name: OMPdecase_AS
description: Orotidine 5'-phosphate decarboxylase, active site

phrase: SNVVVSADVTTSKELLDLADRLGPYITVLKTHIDILTDLSPTTLTSLKSLASKHRFLLFEDRKFVDIGSTVQKQYHGGSLRISEWAHIVNCAMLAGPGIVDALAQTASTPEFRSVYANEVEGGRALLILAEMTSKGSMATGAYTQLSVEAARRHRAFVLGFVATRALNDVLPVSTVDGDEEDFVVFTTGVSLSASGDALGQQYQTPTSAVERGADFIISGRGIYAAEDPLEAVLR
type: DOMAIN
name: OMPdeCOase_dom
description: Orotidine 5'-phosphate decarboxylase domain

phrase: NVVVSADVTTSKELLDLADRLGPYITVLKTHIDILTDLSPTTLTSLKSLASKHRFLLFEDRKFVDIGSTVQKQYHGGSLRISEWAHIVNCAMLAGPGIVDALAQTASTPEFRSVYANEVEGGRALLILAEMTSKGSMATGAYTQLSVEAARRHRAFVLGFVATRALNDVLPVSTVDGDEEDFVVFTTGVSLSASGDALGQQYQTPTSAVERGADFIISGRGIYAAEDPLEAVLR
type: DOMAIN
name: OMPdeCOase_dom
description: Orotidine 5'-phosphate decarboxylase domain
Protein sequence:
MSLFNNHPELDFTMREMLIDWLINIYFDQNVEISNRSLVSGIMMIDRYIYLEKTSISRKMYQGIGVICLNLACKLDDTKILGLDYCEYICAGIYTADILSNLEKRILKVFKFGLHFKNILHYIKLISIKENVDDTVYVFARLMLITILFKTNYLTIKTKSMAKNLMNFSKWFVNNKNVEIKNPIHIYFFTELRRYITHPHFTSINRLAKEFRIFSLIKSRIPNIIYLEKPNVFSKEIIPIELQNSLTIEYTENQLNNMNVIEKLGIGSFGLVNKVKFDNTEIALKTHHPDDSKEIIVESLREINNMIMLDHPNIIKMHGYYYSQGITHIGLELCDMPLYKKLDKGNLSPELKKSFIIQLLCGLKYLHNNNIIHRDLTSSNVLIKGDTLKICDFGCSRFVYDKKIIGNYSLDVCSVRYRAIEILNGILPYNEKIDIWSCACLIAEILGEKFLFRGRNEIEVLDSINRLLGKTVGSGRVGFSMLEKHYPNETQIIYKMLDFDPSNRPNAKLVLKIFSECFVAQSELLVNNQKTTIDKNQIS

Annotated regions:
phrase: LGIGSFGLVNKVKFDNTEIAL
type: BINDING_SITE
name: Protein_kinase_ATP_BS
description: Protein kinase, ATP binding site

phrase: IIHRDLTSSNVL
type: ACTIVE_SITE
name: Tyr_kinase_AS
description: Tyrosine-protein kinase, active site

phrase: MNVIEKLGIGSFGLVNKVKFDNTEIALKTHHPDDSKEIIVESLREINNMIMLDHPNIIKMHGYYYSQGITHIGLELCDMPLYKKLDKGNLSPELKKSFIIQLLCGLKYLHNNNIIHRDLTSSNVLIKGDTLKICDFGCSRFVYDKKIIGNYSLDVCSVRYRAIEILNGILPYNEKIDIWSCACLIAEILGEKFLFRGRNEIEVLDSINRLLGKTVGSGRVGFSMLEKHYPNETQIIYKMLDFDPSNRPNAKLVLKIFSECF
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain

phrase: FNNHPELDFTMREMLIDWLINIYFDQNVEISNRSLVSGIMMIDRYIYLEKTSISRKMYQGIGVICLNLACKLDDTKILGLDYCEYICAGIYTADILSNLEKRILKVFKFG
type: DOMAIN
name: Cyclin_N
description: Cyclin, N-terminal

phrase: NVIEKLGIGSFGLVNKVKFDNTEIALKTHHPDDSKEIIVESLREINNMIMLDHPNIIKMHGYYYSQGITHIGLELCDMPLYKKLDKGNLSPELKKSFIIQLLCGLKYLHNNNIIHRDLTSSNVLIKGDTLKICDFGCSRFVYDKKIIGNYSLDVCSVRYRAIEILNGILPYNEKIDIWSCACLIAEILGEKFLFRGRNEIEVLDSINRLLGKTVGSGRVGFSMLEKHYPNETQIIYKMLDFDPSNRPNAKLV
type: DOMAIN
name: Prot_kinase_dom
description: Protein kinase domain
Protein sequence:
MEFKQGDWVRIERNGTVYEGKVMPSMEGYITIKMKSGYNAGFSIDKVRITLLENNGETANGSRNGGKGCKTNEEELPEPGKKLPKIAILSTGGTIASKIDYRTGAVTSQFTADDILAAIPELKEIADFKGRVISSILSENMDSDSWQNLSKAVVEEIEAGADGVIVTHGTDTMMYSAAALSFMIKTPVPIVFVGSQRSADRPSSDNAMNAICAARVAISDIAEVVVVMHGTTSDDFCEIHRGTKVRKLHTSRRDAFKSVNSLPVGTVDYGTGEIKTFIDYTRRGEKALKFKPGMEPKCALVKFTPGADPTVLDYYISNGYKGLVVEGTGLGHISTKWIPLLRKATDAKMPVIVTSQCLNGRICDRVYDTGRDMLKAGAIEGEDTLPETALVKLMWVLGQTDDFEKAAGMLREDLSGEITECTQR

Annotated regions:
phrase: GVIVTHGTDT
type: ACTIVE_SITE
name: Asparaginase/glutaminase_AS2
description: Asparaginase/glutaminase, active site 2

phrase: KIAILSTGGTIASKIDYRTGAVTSQFTADDILAAIPELKEIADFKGRVISSILSENMDSDSWQNLSKAVVEEIEAGADGVIVTHGTDTMMYSAAALSFMIKTPVPIVFVGSQRSADRPSSDNAMNAICAARVAISDIAEVVVVMHGTTSDDFCEIHRGTKVRKLHTSRRDAFKSVNSLPVGTVDYG
type: DOMAIN
name: L-asparaginase_N
description: L-asparaginase, N-terminal

phrase: ALVKFTPGADPTVLDYYISNGYKGLVVEGTGLGHISTKWIPLLRKATDAKMPVIVTSQCLNGRICDRVYDTGRDMLKAGAIEGEDTLPETALVKLMWVLGQTDDFEKA
type: DOMAIN
name: Asparaginase_C
description: Asparaginase/glutaminase, C-terminal

phrase: ILSTGGTI
type: ACTIVE_SITE
name: Asparaginase/glutaminase_AS1
description: Asparaginase/glutaminase, active site 1

phrase: FKQGDWVRIERNGTVYEGKVMPSMEGYITIKMKSGYNAGFSIDKVRITL
type: DOMAIN
name: GatD_N
description: GatD, N-terminal
Protein sequence:
MNFETVIGLEVHVELKTESKIFSASPNHFGAEPNANTSVIDLGYPGVLPVLNKAAVEFAMKAAMALNCEVATDTKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVDGTKKKIGITRLHLEEDAGKLTHSGNGYSLVDFNRQGTPLIEIVSEPDIRTPQEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPVGQEEFGTKTELKNLNSFNFVRKGLEYEEKRQAQVLLSGGEILQETRRYDEAANKTVLMRVKEGSDDYRYFPEPDLVALHIDDEWKARIRSEIPELPDARKKRYVEELGLPAYDAMVLTLTKEMSDFFEETIAKGADPKLASNWLMGEVSGYLNAEQKELDEVALTPDGLAKMIQLIEKGTISSKIAKKVFKDLIEKGGDPEEIVKAKGLVQISDEGELRKYVVEVLDNNQQSIDDFKNGKDRAIGFLVGQIMKATKGKANPPMVNKLLLEEINKR

Annotated regions:
phrase: TVIGLEVHVELKTESKIFSASPNHFGAEPNANTSVIDLGYPGVLPVLNKAAVEFAMKAAMALNCEVATDTKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVDGTKKKIGITRLHLEEDAGKLTHSGNGYSLVDFNRQGTPLIEIVSEPDIRTPQEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPVGQEEFGTKTELKNLNSFNFVRKGLEYEEKRQAQVLLSGGEILQETRRYDEAANKTVLMRVKEGSDDYRYFPEPDLVALHIDDE
type: DOMAIN
name: Asn/Gln-tRNA_Trfase_suB/E_cat
description: Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic

phrase: DFFEETIAKGADPKLASNWLMGEVSGYLNAEQKELDEVALTPDGLAKMIQLIEKGTISSKIAKKVFKDLIEKGGDPEEIVKAKGLVQISDEGELRKYVVEVLDNNQQSIDDFKNGKDRAIGFLVGQIMKATKGKANPPMVNKLLLEE
type: DOMAIN
name: Asn/Gln_amidotransferase
description: Asn/Gln amidotransferase

phrase: DFFEETIAKGADPKLASNWLMGEVSGYLNAEQKELDEVALTPDGLAKMIQLIEKGTISSKIAKKVFKDLIEKGGDPEEIVKAKGLVQISDEGELRKYVVEVLDNNQQSIDDFKNGKDRAIGFLVGQIMKATKGKANPPMVNKLLLEE
type: DOMAIN
name: Asn/Gln_amidotransferase
description: Asn/Gln amidotransferase

phrase: FNRQGTPLIEIVSE
type: CONSERVED_SITE
name: Gln-tRNA_amidoTrfase_suB_CS
description: Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site
Protein sequence:
MKAVVLTLAVLFLTGSQARHFWQQDEPQSSWDRVKDFATVYVEAIKDSGRDYVAQFEASALGKQLNLKLLDNWDTLASTLSKVREQLGPVTQEFWDNLEKETAALRQEMNKDLEEVKQKVQPYLDEFQRKWHEEVEIYRQKVAPLGEEFREGARQKVQELQDRLSPLAQELRDRARAHVEKQLAPYSDDLRQRLTARLEALKEGGGSLAEYHAKATEQLKALGEKAKPALEDLRQGLMPVLESLKVSILAAIDEASKKLNAQ

Annotated regions:
Protein sequence:
MPMCTAEEAIEEIRSGRMLILVDDEDRENEGDLTIAAEHVTPEIINFMAMHGRGLICLAMAPEWVDKLQLPLMARRNESKFGTNFTVSIEARQGVTTGISAKDRATTILTAVKDDVKPEDIVTPGHIFPLRAQKGGVMVRAGQTEGSVDLARLAGLKPAAVICEIIRDDGEMARMPDLVEFAEKHGLKIATIRDLIRYRMQPGQLSVQRVAEAKMPTKYGDFTVIAYENDHGDETHLAMVKGDIKNQDAVLVRVHSECLTGDVLGSLRCDCGDQLAAAMCTVAAEGAGVVLYMRQEGRGIGLANKIKAYALQDQGYDTVEANHKLGFKADLRDYGIGAQILVDLGVRKMRMMTNNPKKIVGIEGYGIQVVERVPIEMHACEFNENYLRTKKEKMGHMLHLSDEGQEQ

Annotated regions:
phrase: RVAEAKMPTKYGDFTVIAYENDHGDETHLAMVKGDIKNQDAVLVRVHSECLTGDVLGSLRCDCGDQLAAAMCTVAAEGAGVVLYMRQEGRGIGLANKIKAYALQDQGYDTVEANHKLGFKADLRDYGIGAQILVDLGVRKMRMMTNNPKKIVGIEGYGIQVVERV
type: DOMAIN
name: GTP_cyclohydro_II
description: GTP cyclohydrolase II
Protein sequence:
MSWLTEYVRPKIRTLLGRRDVPDNLWVQCPACQQMIFARDLEKNQRVCTHCDHHMRGTALERLKWTLDEGYTRIELPKAPQDPLRFRDSKRYTDRLRDAREKTHLDDAIVVAHGTIEGQKAVVAAMAFEFMGGSMGAAVGEGIVAAAQLAVLQKAPFIIFTASGGARMQEAAISLMQMPRTTIATRMVKEAGLPFIVVLTDPTTGGVTASFAMLGDIQIAEPKALIGFAGARVIEDTTREKLPEGFQRAEFLLEHGIVDMVVRRADMRATLSRVIALLTEGVTLPKVESVASLTEAKQPARTADA

Annotated regions:
phrase: DAREKTHLDDAIVVAHGTIEGQKAVVAAMAFEFMGGSMGAAVGEGIVAAAQLAVLQKAPFIIFTASGGARMQEAAISLMQMPRTTIATRMVKEAGLPFIVVLTDPTTGGVTASFAMLGDIQIAEPKALIGFAGARVIEDTTR
type: DOMAIN
name: AcCoA_carboxyl_beta
description: Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta

phrase: WVQCPACQQMIFARDLEKNQRVCTH
type: DOMAIN
name: Znf-ACC
description: Acetyl-coA carboxylase zinc finger domain

phrase: LWVQCPACQQMIFARDLEKNQRVCTHCDHHMRGTALERLKWTLDEGYTRIELPKAPQDPLRFRDSKRYTDRLRDAREKTHLDDAIVVAHGTIEGQKAVVAAMAFEFMGGSMGAAVGEGIVAAAQLAVLQKAPFIIFTASGGARMQEAAISLMQMPRTTIATRMVKEAGLPFIVVLTDPTTGGVTASFAMLGDIQIAEPKALIGFAGARVIEDTTREKLPEGFQRAEFLLEHGIVDMVVRRADMRATLSRVIALLTEGVTLPKVESVAS
type: DOMAIN
name: COA_CT_N
description: Acetyl-coenzyme A carboxyltransferase, N-terminal
Protein sequence:
MSYKFPNYLRYADTHEYVKEENGLFKIGVSEFAIDQLGDIVFVELVEKGTNLQKGETFGTIESVKAVEEVYLPFSGEVISVNEGVIDNPEILQNDPIGDGWLLIIKSESNVLLDELMNSDEYKSKVVPN

Annotated regions:
phrase: GTNLQKGETFGTIESVKAVEEVYLPFSGE
type: BINDING_SITE
name: 2-oxoA_DH_lipoyl-BS
description: 2-oxo acid dehydrogenase, lipoyl-binding site

phrase: LFKIGVSEFAIDQLGDIVFVELVEKGTNLQKGETFGTIESVKAVEEVYLPFSGEVISVNEGVIDNPEILQNDPIGDGWLLII
type: DOMAIN
name: Biotin_lipoyl
description: Biotin/lipoyl attachment
Protein sequence:
MKLLVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEELEARLNALLRRSSGFVQSTIEAGPLVLDLNRKQALVEEQPVALTAYEYRILEYLMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYLFTERCR

Annotated regions:
phrase: LVLDLNRKQALVEEQPVALTAYEYRILEYLMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYL
type: DOMAIN
name: OmpR/PhoB-type_DNA-bd
description: OmpR/PhoB-type DNA-binding domain

phrase: EQPVALTAYEYRILEYLMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYL
type: DOMAIN
name: OmpR/PhoB-type_DNA-bd
description: OmpR/PhoB-type DNA-binding domain

phrase: KLLVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEELEARLNAL
type: DOMAIN
name: Sig_transdc_resp-reg_receiver
description: Signal transduction response regulator, receiver domain

phrase: MKLLVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEELEAR
type: DOMAIN
name: Sig_transdc_resp-reg_receiver
description: Signal transduction response regulator, receiver domain

phrase: QPVALTAYEYRILEYLMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYL
type: DOMAIN
name: OmpR/PhoB-type_DNA-bd
description: OmpR/PhoB-type DNA-binding domain

phrase: QSTIEAGPLVLDLNRKQALVEEQPVALTAYEYRILEYLMRHHQQVVAKERLMEQLYPDDEERDANVIEVLVGRLRRKLEACGGFKPIDTVRGQGYLFT
type: DOMAIN
name: OmpR/PhoB-type_DNA-bd
description: OmpR/PhoB-type DNA-binding domain

phrase: LVVEDEALLRHHLYTRLGEQGHVVDAVPDAEEALYRVSEYHHDLAVIDLGLPGMSGLDLIRELRSQGKSFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEELEAR
type: DOMAIN
name: Sig_transdc_resp-reg_receiver
description: Signal transduction response regulator, receiver domain
Protein sequence:
MDRAVSQVALENDEREAKNTWRLIFRIAILLLTVVTLATSVASLVYSMGASTPSDLVGIPTRISRAEEKITSALGSNQDVVDRIYKQVALESPLALLNTETTIMNAITSLSYQINGAANNSGWGAPIHDPDFIGGIGKELIVDNASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHSHSHQYLALGVLRTTATGRIFFSTLRSISLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYNSAVPTLMAHGRLGFDGQYHEKDLDVTTLFEDWVANYPGVGGGSFIDGRVWFSVYGGLKPNSPSDTVQEGKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRIQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRILTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFNAFTRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHTLRGVFGTMLDSEQARLNPASAVFDSTSRSRITRVSSSSTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKNDGVREARSG

Annotated regions:
Protein sequence:
MLGIDVKKTKEELIISWQLAEITIPLRDVIEVTEDATYAGVEETSAIRIGTAYGTTDRILIKTVKQNYVLFTTNKVSILNAINAKN

Annotated regions:
phrase: LGIDVKKTKEELIISWQLAEITIPLRDVIEVTEDATYAGVEETSAIRIGTAYGTTDRILIKTVKQNYVLFTTNKVSILNAI
type: DOMAIN
name: PH_SunI-like
description: Sublancin immunity protein SunI-like, PH domain
Protein sequence:
MKTKFCTGGEAEPSPLGLLLSCGGNAAPTPGVGQQRDAAGELESKQLGGRTQPLALPPPPPPPLPLPPPPSPPLADEQPEPRTRRRAYLWCKEFLPGAWRGLREDQFHISVIRGGLSNMLFQCSLPDSIASVGDEPRKVLLRLYGAILKMRSCNKEGSEQAQNENEFQGAEAMVLESVMFAILAERSLGPKLFGIFPQGRLEQFIPSRRLDTEELRLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLNQVLRLKFSREARVQQLHKILSYNLPLELENLRSLLQYTRSPVVFCHNDCQEGNILLLEGQENSERRKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYTYEKYPFFRANIQKYPSRKQQLHFISSYLTTFQNDFESLSSEEQFATKEDMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMEYAQARFEAYFDQKRKLGV

Annotated regions:
Protein sequence:
MSVWTIILAAGQGSRLAQAGLDTKKQFLHHEGAPLYWKSVRTLASVPAIKGFVFVFPPEELDACTKDVESLSSTDDLSMPCLCVAGGARRQDSVFSGLQALPKACSKVLVHDSARPFASAKLAQALISALEHGAEAAIPGLPVTDTIKVIDQDDTVTQTLNRSELRAVQTPQAFDTAALIRAHLACEKKQLSVTDDASMIEATGGTVRIVPGEAGNIKITTPEDLSMLNAQAPQTMLPCVGWGYDVHRYGAGRPFRLGGIPVDTDIEVIAHSDGDVLLHALADALLGCLGLGDIGKHFPDTDAKFEGIESSILVNEVLQEVEKKALTITHVDLTVIAQRPKLASYRERIQKNVANLLRIDKSHVNFKATTEEKLGFTGAKKGIKAVACVSAMYPANQQA

Annotated regions:
phrase: VGWGYDVHRYGAGRPFRLGGIPVDTDIEVIAHSDGDVLLHALADALLGCLGLGDIGKHFPDTDAKFEGIESSILVNEVLQEVEKKALTITHVDLTVIAQRPKLASYRERIQKNVANLLRIDKSHVNFKATTEEKLGFTGAKKGIKAVAC
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: VLVHDSA
type: CONSERVED_SITE
name: ISPD_synthase_CS
description: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site

phrase: VRIVPGEAGNIKITTPEDLSMLNAQAPQTMLPCVGWGYDVHRYGAGRPFRLGGIPVDTDIEVIAHSDGDVLLHALADALLGCLGLGDIGKHFPDTDAKFEGIESSILVNEVLQEVEKKALTITHVDLTVIAQRPKLASYRERIQKNVANLLRIDKSHVNFKATTEEKLGFTGAKKGIKAVACVSA
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: VGWGYDVHRYGAGRPFRLGGIPVDTDIEVIAHSDGDVLLHALADALLGCLGLGDIGKHFPDTDAKFEGIESSILVNEVLQEVEKKALTITHVDLTVIAQRPKLASYRERIQKNVANLLRIDKSHVNFKATTEEKLGFTGAKKGIKAVAC
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: VGWGYDVHRYGAGRPFRLGGIPVDTDIEVIAHSDGDVLLHALADALLGCLGLGDIGKHFPDTDAKFEGIESSILVNEVLQEVEKKALTITHVDLTVIAQRPKLASYRERIQKNVANLLRIDKSHVNFKATTEEKLGFTGAKKGIKAVACV
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

phrase: SDGDVLLHALADALL
type: CONSERVED_SITE
name: MECDP_synthase_CS
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site

phrase: PCVGWGYDVHRYGAGRPFRLGGIPVDTDIEVIAHSDGDVLLHALADALLGCLGLGDIGKHFPDTDAKFEGIESSILVNEVLQEVEKKALTITHVDLTVIAQRPKLASYRERIQKNVANLLRIDKSHVNFKATTEEKLGFTGAKKGIKAVACVSAM
type: DOMAIN
name: MECDP_synthase
description: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Protein sequence:
MDVDFGAQAGQSYRTVQLSAKEVLAAGRRQHYCNMIDLLASSCKSSGLIATSFTDDELVEFWLGDILPLMFDADRKIQDCAVAALAEALVALDVSVIHSAKCWPQIRSEFVDKYTIIIGEMRDAKNSNWHKIWTLLVQIMDEDLLRGCVYINKFLALVELGFRNPDNGVRSEAFLCWRVLIKIFAAYDELTSAKRLRLLLIPLRTSQSRSSHVSGIKLRVWWYLLSCLDHELPKSFDSAVEHFLAFMLGGGPRNLATGLAHNYQTARELALPCLVALWGVESSEPLQRLMRELRLETLVQPSPLMSVEVFQQHWKPLLAAAVSGLKLLTENDATEAEQLLLQLLVRNLCLAMFRLAVAPFNVACCSEIEKILQAEDNSGGRVVRALFNTIAADNLVMERVSGSDHLDVLEAYLKLVLKSKTEVPAAILQRSIACIFAVDRIEANNQNEFRMLGSFAELLMQANDEEDFEGFAFKLQVWRQVSQALSNYLRNNALEYRVAHNASLLDTWLLWPLQTLAAFAGRRASNSFDASFCDQWRQLVNAGQNAPGRKKFLTDLKATLTDLLKSKDEPLFAELFDAYVTSLIKFGLCKEAPLYKDVFGLLQTIFEQPSSQKTLEACLNTLRNLVVELRQNELMVVFDSLKPTLSSGIQCWNKMKCEGGFLEEWKRGIQEKFRKLPMKTMANQLKELFKADDLFVIIPSVWSLNPEKLTDRQKERFAEKSDIPALYNDMSQSQDSASIKPWTPKKVVIAKSKQGELALTGKDDNGEVIDITASEESEKEPVRVDVVTPIRKKPGRKSQAQKELEAAARAASLAEEPPKRQTRTRAAQKETEQVAQPQPAFEPQLRSPKKLPPSPVVQSTAAAVKQAKVAKPTPVVVIAQSEDLFPEVAAEPEPQPEPVKKPDPVPETTQLTPPDVPLEAVPSTQLPGSSGDPAASAGAVAAGEMSPKKSGTRIYNLSSPPDRKQTNNSSSPTLRPKPTGHLTGRGAQLINMIRNKKLDAASGSPYACMSTSRLVHQVTPARAQDRAEQVSTPTSELNELTGTDHTSTPIQAPPSKDLLVFSKRLPSPSASPSVSILKRKLRCESLDDVTLDSPALKRKRVSFHDPPVSVTKEYLRDAEETRSSLKPKRCLLMDKVAQTTEMRQALRRRGRLDSIIEIERFASEQTARTATTDKSLDKSTGEAPEEDAFTSLKWNDTGNAHNISISEEPVKAMEVESELETAGQDLAIMDPEAALDLAVAQLPLESVLQRYFDKSPLKSAGMLAKFLSAQMTANEKLKTNVLETLSENHSKDFLDHAVRENLSSVVCDRLNPTSVLEYVCAKSKISASCRNGLLAQVPEILKSGPRSDSERLAFVQQLMVQCSPGDDLLLDLIDLLMRTRRERNNSTSTHISKGVVSAVGSPDNVAETAADSSSNL

Annotated regions:
phrase: VEFWLGDILPLMFDADRKIQDCAVAALAEALVALDVSVIHSAKCWPQIRSEFVDKYTIIIGEMRDAKNSNWHKIWTLLVQIMDEDLLRGCVYINKFLALVELGFRNPDNGVRSEAFLCWRVLIKIFAAYDELTSAKRLRLLLIPLRTSQSRSSHVSGIKLRVWWYLLSCLDHELPKSFDS
type: DOMAIN
name: Rif1_N
description: Telomere-associated protein Rif1, N-terminal
Protein sequence:
MIYQAETLQVKEVQDGVAEILFCAPNSVNKLDLATLASLDKALDALTAHSGLKGVMLTSDKEAFIVGADITEFLGLFAKPEEELDQWLQFANSIFNKLEDLPVPTVAVVKGHTLGGGCECVLATDLRIGDKTTSIGLPETKLGIMPGFGGCVRLPRVIGADSAMEIITQGKACRAEEALKIGLLDAVVDSDRLYASALQTLTDAINEKIDWKARRQQKTSALTLSKLEAMMSFTMAKGLVAQVAGPHYPAPMTAVVTIEEGARFARNQALDIERKHFVKLAKSEEAKALVGLFLNDQYIKGIAKKAAKSANKETQRAAVLGAGIMGGGIAYQSALKGVPVIMKDIAQASLDLGMTEASKLLNKQLERGKIDGFKMAGILASITPSLHYAGIDNADIIVEAVVENPKVKAAVLSEVEEQVSEETVLTSNTSTIPINLLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGEHTSDETINRVVAYAAKMGKSPIVVNDCPGFFVNRVLFPYFGGFSMLLRDGADFTQIDKVMERKFGWPMGPAYLLDVVGIDTAHHAQAVMAQGFPERMGKQGRDAIDALFEANKYGQKNGSGFYTYTMDKKGKPKKAFSDEIVPILAPVCAAQQAFDDQTIIQRMMIPMINEVVLCLQEGIIASAQEADMALVYGLGFPPFRGGVFRYLDSVGIANFVAMAQQHVELGAMYQVPQMLIDMAEKGQTFYGAQQQGSI

Annotated regions:
phrase: AAVLGAGIMGGGIAYQSALKGVPVIMKDIAQASLDLGMTEASKLLNKQLERGKIDGFKMAGILASITPSLHYAGIDNADIIVEAVVENPKVKAAVLSEVEEQVSEETVLTSNTSTIPINLLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGEHTSDETINRVVAYAAKMGKSPIVVND
type: DOMAIN
name: 3-OHacyl-CoA_DH_NAD-bd
description: 3-hydroxyacyl-CoA dehydrogenase, NAD binding

phrase: DCPGFFVNRVLFPYFGGFSMLLRD
type: CONSERVED_SITE
name: 3-OHacyl-CoA_DH_CS
description: 3-hydroxyacyl-CoA dehydrogenase, conserved site

phrase: GFFVNRVLFPYFGGFSMLLRDGADFTQIDKVMERKFGWPMGPAYLLDVVGIDTAHHAQAVMAQGFPERMGKQGRDAIDALFEANKYGQKNGSGFYT
type: DOMAIN
name: 3HC_DH_C
description: 3-hydroxyacyl-CoA dehydrogenase, C-terminal

phrase: IIQRMMIPMINEVVLCLQEGIIASAQEADMALVYGLGFPPFRGGVFRYLDSVGIANFVAMAQQHVELGAMYQVPQMLIDMAEKG
type: DOMAIN
name: 3HC_DH_C
description: 3-hydroxyacyl-CoA dehydrogenase, C-terminal
Protein sequence:
MRLASPRSLFVIAFLGSALLIAIALYMEHVMGLAPCPLCIVQRICVIGFGLVCLVAAIHGPAKVGRRVYAAIAALFVAAGAATAIRQIWLQSVPADQLPSCLPSLEYMMEALPFQEIARLVLHGTAECAEVSWTMLGMSIPEWSLLGFIGMAIVCLWQLLRRD

Annotated regions:
Protein sequence:
MRNAQKSSGMPFHRYTPFQDQITVEMPDRTWPDKVITKAPRWCAVDLRDGNQALIDPMSPARKMKMFDLLVRMGYKEIEVGFPSASQTDFDFVRQLIEGNHIPDDVTIQVLTQAREHLIERTYESLVGAKQAIVHLYNSTSVLQRRVVFNQDEDGILDIALQGARLCRKYEETLADTHITYEYSPESFTGTELEYAVRVCNAVADVFEASADRQVIINLPATVEMATPNVYADSIEWMSRHLHPREGIILSLHPHNDRGTGVAAAELGYMAGADRIEGCLFGNGERTGNVDLVTLGLNLFVQGIDPMIDFSDIDDVRRTVEYCNQLPVPERSPYGGDLVFTAFSGSHQDAIKKGFEALERDAAAAGKDVADVTWQVPYLPVDPKDLGRSYEAVIRVNSQSGKGGVAYLLKNEHSLDLPRRAQIEFSGVIQRRTDTVGGEVSGAQLWQIFQDEYLPSGKADGQWGRYSLGSVKTETDDDGGMTLHASLTVDGAQVSRTGTGNGPIAALLNILTQDGVDVRVLDYSEHALSEGGNAMAAAYVECAVGERVLWGVGIDANTSMSSLKAVISAVNRAIRDAQS

Annotated regions:
phrase: PRWCAVDLRDGNQALIDPMSPARKMKMFDLLVRMGYKEIEVGFPSASQTDFDFVRQLIEGNHIPDDVTIQVLTQAREHLIERTYESLVGAKQAIVHLYNSTSVLQRRVVFNQDEDGILDIALQGARLCRKYEETLADTHITYEYSPESFTGTELEYAVRVCNAVADVFEASADRQVIINLPATVEMATPNVYADSIEWMSRHLHPREGIILSLHPHNDRGTGVAAAELGYMAGADRIEGCLFGNGERTGNVDLVTLGLNLFVQGIDPMIDFSDIDDVRRT
type: DOMAIN
name: PYR_CT
description: Pyruvate carboxyltransferase

phrase: DLVFTAFSGSHQDAIKKGFEALERDAAAAGKDVADVTWQVPYLPVDPKDLGRSYEAVIRVNSQSGKGGVAYLL
type: DOMAIN
name: LeuA-like_post-cat
description: 2-isopropylmalate synthase-like, post-catalytic domain

phrase: APRWCAVDLRDGNQALIDPMSPARKMKMFDLLVRMGYKEIEVGFPSASQTDFDFVRQLIEGNHIPDDVTIQVLTQAREHLIERTYESLVGAKQAIVHLYNSTSVLQRRVVFNQDEDGILDIALQGARLCRKYEETLADTHITYEYSPESFTGTELEYAVRVCNAVADVFEASADRQVIINLPATVEMATPNVYADSIEWMSRHLHPREGIILSLHPHNDRGTGVAAAELGYMAGADRIEGCLFGNGERTGNVDLVTLGLNLFVQGIDPMIDFSDIDDVRRTVE
type: DOMAIN
name: LeuA_N_DRE-TIM
description: LeuA, N-terminal catalytic TIM barrel domain

phrase: EVSGAQLWQIFQDEYLPSGKADGQWGRYSLGSVKTETDDDGGMTLHASLTVDGAQVSRTGTGNGPIAALLNILTQDGVDVRVLDYSEHALSEGGNAMAAAYVECAVGERVLWGVGIDANTSMSSLKAVISAVNRA
type: DOMAIN
name: 2-isopropylmalate_synth_dimer
description: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain

phrase: EVSGAQLWQIFQDEYLPSGKADGQWGRYSLGSVKTETDDDGGMTLHASLTVDGAQVSRTGTGNGPIAALLNILTQDGVDVRVLDYSEHALSEGGNAMAAAYVECAVGERVLWGVGIDANTSMSSLKAVISAVNR
type: DOMAIN
name: 2-isopropylmalate_synth_dimer
description: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain

phrase: PRWCAVDLRDGNQALIDPMSPARKMKMFDLLVRMGYKEIEVGFPSASQTDFDFVRQLIEGNHIPDDVTIQVLTQAREHLIERTYESLVGAKQAIVHLYNSTSVLQRRVVFNQDEDGILDIALQGARLCRKYEETLADTHITYEYSPESFTGTELEYAVRVCNAVADVFEASADRQVIINLPATVEMATPNVYADSIEWMSRHLHPREGIILSLHPHNDRGTGVAAAELGYMAGADRIEGCLFGNGERTGNVDLVTLGLNLFVQGIDPMIDFSDI
type: DOMAIN
name: PYR_CT
description: Pyruvate carboxyltransferase

phrase: LSLHPHNDRGTGV
type: CONSERVED_SITE
name: AIPM/Hcit_synth_CS
description: Alpha-isopropylmalate/homocitrate synthase, conserved site

phrase: LRDGNQALIDPMSPAR
type: CONSERVED_SITE
name: AIPM/Hcit_synth_CS
description: Alpha-isopropylmalate/homocitrate synthase, conserved site
Protein sequence:
MSAKDVRFSGDARDRMLRGVDILANAVKVTLGPKGRNVVIEKSFGAPRITKDGVTVAKEIELDDRFENMGAQMVREVASKTNDTAGDGTTTATVLAQAIVREGAKAVAAGMNPMDLKRGIDIAAAAVVKDIGKRAKPVASSAEVAQVGTISSNGDTAIGKMIAQAMQKVGNEGVITVEENKSLETDVDIVEGMRFDRGYLSPYFVTNAEKMTAELDGAYILLHEKKLSGLQAILPLLEAVVKSGKPLLIVAEDIEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLEDIAILTGGQLISDDLGIKLENVTVDMLGRAKKVVIDKENTTIVNGAGKKKDIEARVGQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEIEVKEKKDRVEDALNATRAAVQEGIVPGGGTALLRAKKAVGRIANDNPDVQAGINIVLKALEAPIRQIAENAGVEGSIVVGKVLENKTETFGFDAQKEEYVDMVAKGIIDPAKVVRTALQDAASVAGLLVTTEAMVAELPKEEPAPAMPGGGGMGGMGF

Annotated regions:
phrase: AAVQEGIVPGG
type: CONSERVED_SITE
name: Chaperonin_Cpn60_CS
description: Chaperonin Cpn60, conserved site
Protein sequence:
MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQIMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKYPA

Annotated regions:
Protein sequence:
MGRCFPFTVETQRRAVEHPGPRRRGPSSTSEPLSPFPGELEPRWRWPRCPDGVAGREQLLAQQRMHSLINSVEVKSEVPVTLDPVSPLDLRTDLRMMMPMVDPVLREKQLQQELLLIQQQQHLQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEVERHRREQQQLPPLRGKERGRERAVASTEVKQKLQEFLLSKSATKDSPTNGKNHSVSRHPKLWYTAAHHTSLDQSSPPLSGTSPSYKYPLPGAQDTKDDFPLRKTASEPNLKVRSRLKQKVTERRSSPLLRRKDGNVVTSFKKRVFEVTESSVSSSSPGSGPSSPSNGPSTNMAESSETLLIPPAPHPEQIVSQQRLLIHEESMNLLSLYPSPSLPNITLGLPAVPSQLSASSSIKDKQKCEAPALRPPGVTLPGQYTGSIPASSSHPHAALEGKPNSSHQALLQHLLLKEQMRQQKLLVAGGVPLHPQSPLATKERVSPGLRGAHKLPRHRPLNRTQSAPLPQSTLAQLVIQQQHQQFLEKQKQYQQQVHMNKMLSQSIEQLKQPGSQLEESEEELHGDQPMQEDRAPSSTNSVRSDSSLGPDDSQRGPTLGAVKIKEEPLDSDDDTQPQEMESGEQAALVQQPFLEPQPGHALPTYQAPLASIGTEAFDQHLLVSRTHSSPAVPMVPRPVTDQSLPRASETGVVYDALMLKHQCICGRSALHPEHAGRIQSIWSRLQETGLLSKCERIQGRKASLEELHLVHSDH

Annotated regions:
phrase: VDPVLREKQLQQELLLIQQQQHLQKQLLIAEFQKQHENLTRQHQAQLQEHIKLQQELLAIKQQQELLEKEQKLEQQRQEQEVERHRREQ
type: DOMAIN
name: Hist_deacetylase_Gln_rich_N
description: Histone deacetylase, glutamine rich N-terminal domain
Protein sequence:
MKKLLKQSLLGFALVSMTGAAFADAQSVAELQRRLEQVSQYSADFDQTVRSSKGKQIQSGKGKFQVKRPNLFRMDTKSPQENLIVSDGANLWFYDSFVSQVTVNTVQDAVNNTPFVLLTSSDKSHWDQYDVTQNADTFVLKPKSKKSNLKQFDVRIDQSGMLKGFSTIERDGQSNLYVLRNITGGGVSSDLFKFSVPKGAELDDQRGGKKSKK

Annotated regions:
Protein sequence:
MDLITTTAELASVCARLANYPVVTVDTEFLRETTYYPLLCVVQMASPDEAVVVDALAEGIDLKPFFDLMSNERVLKVFHAARQDIEIVWHQAGIIPHPIFDTQVAAMVLGYGDSIAYDALVERVNGHRPDKTHRFTDWSRRPLTKDQLEYAVADVTHLRDVFAALDADLKKRGRGDWVSEEMEVLTSPKTYDFHPERAWERLKTRVRKPKDLAVMMEVAAWREQEAQSRNIPRSRVLKDDAVGDIAIHAPATPERLATLRSLPKGFEKSQWGADIVAAVQRGLARDPRELPKIEKPRNNTNGAATVELLKVLLRMTSERHAVASKVIATVDDLERIAADDAADVGALRGWRRELFGEAALALKHGQLALAIEKGRVVRVERS

Annotated regions:
phrase: MDLITTTAELASVCARLANYPVVTVDTEFLRETTYYPLLCVVQMASPDEAVVVDALAEGIDLKPFFDLMSNERVLKVFHAARQDIEIVWHQAGIIPHPIFDTQVAAMVLGYGDSIAYDALVERVNGHRPDKTHRFTDWSRRPLTKDQLEYAVADVTHLRDVFAALDADL
type: DOMAIN
name: 3'-5'_exonuclease_dom
description: 3'-5' exonuclease domain

phrase: KPKDLAVMMEVAAWREQEAQSRNIPRSRVLKDDAVGDIAIHAPATPERLATLRSLPKGFEKSQWGADIVAAVQRGLARDPR
type: DOMAIN
name: HRDC_dom
description: HRDC domain

phrase: LITTTAELASVCARLANYPVVTVDTEFLRETTYYPLLCVVQMASPDEAVVVDALAEGIDLKPFFDLMSNERVLKVFHAARQDIEIVWHQAGIIPHPIFDTQVAAMVLGYGDSIAYDALVERVNGHRPDKTHRFTDWSRRPLTKDQLEYAVADVTHLRDVFAALDAD
type: DOMAIN
name: 3'-5'_exonuclease_dom
description: 3'-5' exonuclease domain

phrase: LAVMMEVAAWREQEAQSRNIPRSRVLKDDAVGDIAIHAPATPERLATLRSLPKGFEKSQWGADIVA
type: DOMAIN
name: HRDC_dom
description: HRDC domain