Query: andrew hurrell informatics

Candidate papers:

abstract: Part 1 Policy context for US trade: introduction US trade negotiations in perspective, Robert S. Walters the multilateral trade order the new GATT round, Charles Pearson and Mils Johnson the domestic political setting of US trade policy, Timothy J.C. O'Shea. Part 2 US trade diplomacy: the US Japan semiconductor problem, Timothy J.C. O'Shea under construction US Japan negotiations to open Japan's construction markets to American firms, Ellis Krauss the US Brazilian informatics dispute, Ellene Felder and Andrew Hurrell European Community enlargement and the United States, John Odell and Margit Matzinger Tchakerian.
author_names: Robert S Walters
title: Talking Trade
year: 2020

author_names: Ellene A Felder

Andrew Hurrell
title: The U.S. Brazilian informatics dispute
year: 1991

abstract: This is one of the finest books on the normative dimension of global governance published in the past decade. Utilizing insights from the English School, liberal institutionalism, and constructivism, the author addresses some of the most profound questions on the nature, limitations, and possibilities of global order in the twenty first century. Andrew Hurrell, a former student of Hedley Bull, goes beyond the traditional concept of an anarchical society based on minimalist conditions of coexistence and suggests a fresh approach to understanding what kinds of political organizations we need in the future. To do so, he explores three major challenges in global society: the need to capture shared and common interests, the imperative to manage unequal power, and the need to mediate cultural diversity and value conflict. On Global Order is divided into four parts. The first, which focuses on conceptual frameworks, comprises three chapters that revisit the idea of the anarchical society, explore global liberalism, and analyze the complex system of global governance. Hurrell regards the anarchical society identified by Bull and others in the English School which rested on the preservation of international society, the maintenance of the independence of sovereign states, and the regulation of war and conflict
author_names: Samuel M Makinda
title: On Global Order: Power, Values, and the Constitution of International Society by Andrew Hurrell
venue: Ethics International Affairs
year: 2009

author_names: Ian D Clark
title: On Global Order: Power, Values, and the Constitution of International Society By Andrew Hurrell. New York: Oxford University Press, 2007. 354p. $95.00 cloth, $35.00 paper.
venue: Perspectives on Politics
year: 2008

author_names: Robert M Pallitto
title: On Global Order: Power, Values, and the Constitution of International Societyby Andrew Hurrell
year: 2008

abstract: Catalysis informatics is a distinct subfield that lies at the intersection of cheminformatics and materials informatics but with distinctive challenges arising from the dynamic, surface sensitive, and multiscale nature of heterogeneous catalysis. The ideas behind catalysis informatics can be traced back decades, but the field is only recently emerging due to advances in data infrastructure, statistics, machine learning, and computational methods. In this work, we review the field from early works on expert systems and knowledge engines to more recent approaches utilizing machine learning and uncertainty quantification. The data information knowledge hierarchy is introduced and used to classify various developments. The chemical master equation and microkinetic models are proposed as a quantitative representation of catalysis knowledge, which can be used to generate explanative and predictive hypotheses for the understanding and discovery of catalytic materials. We discuss future prospects for the field, i.
author_names: Andrew J Medford

M Ross Kunz

Sarah M Ewing

Tammie L Borders

Rebecca R Fushimi
title: Extracting Knowledge from Data through Catalysis Informatics
year: 2018

abstract: We introduce a combination of existing and novel approaches to the assessment and prediction of particle properties intrinsic to the formulation and manufacture of pharmaceuticals. Naturally following on from established solid form informatics methods, we return to the drug lamotrigine, re evaluating its context in the Cambridge Structural Database (CSD) We then apply predictive digital design tools built around the CSD System suite of software, including Synthonic Engineering methods that focus on intermolecular interaction energies, to analyze and understand important particle properties and their effects on several key stages of pharmaceutical manufacturing. We present a new, robust workflow that brings these approaches together to build on the knowledge gained from each step and explain how this knowledge can be combined to provide resolutions at decision points encountered during formulation design and manufacturing processes.
author_names: M J Bryant

Ian Rosbottom

Ian J Bruno

R Docherty

Colin M Edge

Robert B Hammond

R H Peeling

Jonathan Pickering

Kevin J Roberts

Andrew G P Maloney
title: "Particle Informatics" Advancing Our Understanding of Particle Properties through Digital Design
venue: Crystal Growth Design
year: 2019

author_names: Chuan Ming Gang
title: Shao Jie Rosemary Foot, John Lewis Gaddis and Andrew Hurrell(eds. Order and Justice in International Relations
year: 2004

author_names: Imtiaz Hussain
title: Regionalism in World Politics: Regional Organization and international order, de Louise Fawcett y Andrew Hurrell
year: 1998

abstract: Adverse drug reactions have been linked with HLA alleles in different studies. These HLA proteins play an essential role in the adaptive immune response for the presentation of self and non self peptides. Anti thyroid drugs methimazole and propylthiouracil have been associated with drug induced agranulocytosis (severe lower white blood cell count) in patients with B*27:05, B*38:02 and DRB1*08:03 alleles in different populations: Taiwanese, Vietnamese, Han Chinese and Caucasian. In this study, informatics methods were used to investigate if any sequence or structural similarities exist between the two associated HLA B alleles, compared with a set of "control" alleles assumed not be associated, which could help explain the molecular basis of the adverse drug reaction. We demonstrated using MHC Motif Viewer and MHCcluster that the two alleles do not have a propensity to bind similar peptides, and thus at a gross level the structure of the antigen presentation region of the two alleles are not similar. We also performed multiple sequence alignment to identify polymorphisms shared by the risk but not by the control alleles and molecular docking to compare the predicted binding positions of the drug allele combinations. Two residues, Cys67 and Thr80, were identified from the multiple sequence alignments to be unique to these risk alleles alone. The molecular docking showed the poses of the risk alleles to favour the F pocket of the peptide binding groove, close to the Thr80 residue, with the control alleles generally favouring a different pocket. The data are thus suggestive that Thr80 may be a critical residue in HLA mediated anti thyroid drug induced agranulocytosis, and thus can guide future research and risk assessment.
author_names: Kerry A Ramsbottom

Daniel F Carr

Daniel J Rigden

Andrew R Jones
title: Informatics investigations into anti thyroid drug induced agranulocytosis associated with multiple HLA B alleles
year: 2019