2022 FIFAワールドカップ・アフリカ1次予選

本記事では、2022 FIFAワールドカップのアフリカ予選のうち1次予選の詳細について示す。2019年9月4日から10日にかけて実施した。

1. フォーマット
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シード順が27位以下のチームを2チームずつ14組に分け、ホーム・アンド・アウェー方式で対戦を行う。各勝者が2次予選に進出する

2. シード順
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組み合わせ抽選は、2019年7月29日正午にエジプト・カイロのCAF本部で行われたFIFA-20190716}}。

1次予選のシード順は、2019年7月のFIFAランキングを基準に定められたFIFA-20190716}}。ポット2に入った国が第1戦のホームゲームを行った。

ノート: 太字は、2次予選進出国を示し、国名の後の括弧書きは2019年7月現在のFIFAランキングの順位である。

3. 対戦結果
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第1戦は2019年9月4日から7日に、第2戦は同年9月8日と10日に実施した。

4. 試合
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合計得点1-1、アウェーゴール数1-0でエチオピアが勝利。

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ジンバブエが2試合合計3-2で勝利。

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ナミビアが2試合合計4-1で勝利。

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タンザニアが合計得点2-2、PK戦3-0で勝利。

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ジブチが2試合合計2-1で勝利。

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マラウイが2試合合計1-0で勝利。

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アンゴラが2試合合計3-1で勝利。

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リベリアが2試合合計3-2で勝利。

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モザンビークが2試合合計3-0で勝利。

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ギニアビサウが2試合合計3-1で勝利。

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赤道ギニアが2試合合計2-1で勝利。

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トーゴが2試合合計2-1で勝利。

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{{Football box |date = |time = |team1 = |score = 0 - 0 |team2 = |stadium = アル・メレイフ・スタジアム