-- DBMS: snowflake
create or replace TABLE TARGETESSENTIALITY (
	"id" VARCHAR(16777216),
	"geneEssentiality" VARIANT
);

INSERT INTO "OPEN_TARGETS_PLATFORM_2"."OPEN_TARGETS_PLATFORM"."TARGETESSENTIALITY" (id, geneEssentiality) VALUES ('ENSG00000159479', '{
  "list": [
    {
      "element": {
        "depMapEssentiality": {
          "list": [
            {
              "element": {
                "screens": {
                  "list": [
                    {
                      "element": {
                        "cellLineName": "PCI-15A",
                        "depmapId": "ACH-002294",
                        "diseaseCellLineId": "SIDM00270",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -7.807123700000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "FaDu",
                        "depmapId": "ACH-000846",
                        "diseaseCellLineId": "SIDM00860",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 5.495375000000000e+00,
                        "geneEffect": -9.907709000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "JHU-029",
                        "depmapId": "ACH-002251",
                        "diseaseCellLineId": "SIDM00690",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -6.127293000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "YD-15",
                        "depmapId": "ACH-000836",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 5.143638000000000e+00,
                        "geneEffect": -6.205750000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "UPCI-SCC-200",
                        "depmapId": "ACH-001701",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.967630000000000e+00,
                        "geneEffect": -1.296157800000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "SKN-3",
                        "depmapId": "ACH-002305",
                        "diseaseCellLineId": "SIDM00375",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -5.158599600000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "H157",
                        "depmapId": "ACH-001347",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.542877000000000e+00,
                        "geneEffect": -1.041709200000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "H3118",
                        "depmapId": "ACH-002239",
                        "diseaseCellLineId": "SIDM00517",
                        "diseaseFromSource": "Salivary Carcinoma",
                        "geneEffect": -8.455066700000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "TR146",
                        "depmapId": "ACH-001675",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -1.294778000000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "UPCI-SCC-152",
                        "depmapId": "ACH-001228",
                        "diseaseCellLineId": "SIDM00398",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 5.747387400000000e+00,
                        "geneEffect": -6.828847500000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "Detroit 562",
                        "depmapId": "ACH-000207",
                        "diseaseCellLineId": "SIDM00831",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.377817600000000e+00,
                        "geneEffect": -7.409348500000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "BB30-HNC",
                        "depmapId": "ACH-002212",
                        "diseaseCellLineId": "SIDM00172",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -8.804400600000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "PCI-38",
                        "depmapId": "ACH-002296",
                        "diseaseCellLineId": "SIDM00155",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -7.060100000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "PCI-6A",
                        "depmapId": "ACH-002298",
                        "diseaseCellLineId": "SIDM00115",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -1.029565200000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "PE/CA-PJ41 (clone D2)",
                        "depmapId": "ACH-000732",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.583158000000000e+00,
                        "geneEffect": -1.512595000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "PE/CA-PJ15",
                        "depmapId": "ACH-000619",
                        "diseaseCellLineId": "SIDM00473",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.349790000000000e+00,
                        "geneEffect": -7.087828500000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "HSC-3",
                        "depmapId": "ACH-000778",
                        "diseaseCellLineId": "SIDM00589",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 5.448901000000000e+00,
                        "geneEffect": -1.006908900000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "Sa3",
                        "depmapId": "ACH-002030",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -8.954682000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "T3M-5",
                        "depmapId": "ACH-002042",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 5.702103600000000e+00,
                        "geneEffect": -5.333275000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "SAT",
                        "depmapId": "ACH-001641",
                        "diseaseCellLineId": "SIDM00350",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.442943600000000e+00,
                        "geneEffect": -9.058932700000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "BICR 16",
                        "depmapId": "ACH-000503",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.948601000000000e+00,
                        "geneEffect": -6.480163000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "BICR 31",
                        "depmapId": "ACH-000228",
                        "diseaseCellLineId": "SIDM00078",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 5.086614000000000e+00,
                        "geneEffect": -1.315942500000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "KON",
                        "depmapId": "ACH-001542",
                        "diseaseCellLineId": "SIDM00604",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.777683000000000e+00,
                        "geneEffect": -8.886710400000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "DOK",
                        "depmapId": "ACH-002234",
                        "diseaseCellLineId": "SIDM00540",
                        "diseaseFromSource": "Head and Neck Carcinoma, Other",
                        "geneEffect": -1.295284400000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "HSC-2",
                        "depmapId": "ACH-000472",
                        "diseaseCellLineId": "SIDM00590",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 3.911691700000000e+00,
                        "geneEffect": -9.776340000000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "JHU-011",
                        "depmapId": "ACH-002249",
                        "diseaseCellLineId": "SIDM00128",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -7.165561300000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "Ca9-22",
                        "depmapId": "ACH-002043",
                        "diseaseCellLineId": "SIDM00489",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.771885400000000e+00,
                        "geneEffect": -9.915871000000001e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "UPCI-SCC-116",
                        "depmapId": "ACH-001698",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 3.687060600000000e+00,
                        "geneEffect": -7.881954300000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "SNU-1066",
                        "depmapId": "ACH-000682",
                        "diseaseCellLineId": "SIDM00170",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.723558400000000e+00,
                        "geneEffect": -1.096395700000000e+00
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "JHU-022",
                        "depmapId": "ACH-002250",
                        "diseaseCellLineId": "SIDM00127",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "geneEffect": -8.701080700000000e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "BICR 56",
                        "depmapId": "ACH-000771",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
                        "expression": 4.024142300000000e+00,
                        "geneEffect": -7.889131000000000e-01
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                    },
                    {
                      "element": {
                        "cellLineName": "OSC-19",
                        "depmapId": "ACH-001625",
                        "diseaseCellLineId": "SIDM00566",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                        "geneEffect": -9.213713000000000e-01
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                    },
                    {
                      "element": {
                        "cellLineName": "UPCI-SCC-029A",
                        "depmapId": "ACH-001691",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                        "geneEffect": -6.267751499999999e-01
                      }
                    },
                    {
                      "element": {
                        "cellLineName": "H376",
                        "depmapId": "ACH-001510",
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                    },
                    {
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                        "depmapId": "ACH-000415",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    },
                    {
                      "element": {
                        "cellLineName": "YD-38",
                        "depmapId": "ACH-000762",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    },
                    {
                      "element": {
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                    },
                    {
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                        "geneEffect": -1.229534500000000e+00
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                    },
                    {
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                        "cellLineName": "RPMI 2650",
                        "depmapId": "ACH-001385",
                        "diseaseCellLineId": "SIDM00809",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "depmapId": "ACH-000832",
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                    {
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                    {
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                    {
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "depmapId": "ACH-000518",
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "depmapId": "ACH-000630",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
                      "element": {
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                        "geneEffect": -6.561585700000000e-01
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                    {
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                        "depmapId": "ACH-001626",
                        "diseaseCellLineId": "SIDM00565",
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                    {
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                    {
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                        "diseaseCellLineId": "SIDM00501",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
                      "element": {
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                        "depmapId": "ACH-000238",
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    {
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                        "depmapId": "ACH-000618",
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                    {
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                    {
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                    {
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                    {
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                    {
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                    },
                    {
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                        "depmapId": "ACH-002297",
                        "diseaseCellLineId": "SIDM00043",
                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    },
                    {
                      "element": {
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                    },
                    {
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                    },
                    {
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                        "diseaseFromSource": "Head and Neck Squamous Cell Carcinoma",
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                    }
                  ]
                },
                "tissueId": "UBERON_0007811",
                "tissueName": "craniocervical region"
              }
            },
            {
              "element": {
                "screens": {
                  "list": [
                    {
                      "element": {
                        "cellLineName": "MONO-MAC-1",
                        "depmapId": "ACH-001129",
                        "diseaseCellLineId": "SIDM01022",
                        "diseaseFromSource": "Acute Myeloid Leukemia",
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                    },
                    {
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