-- DBMS: snowflake
create or replace TABLE MASKED_SOMATIC_MUTATION_HG38_GDC_R39 (
	"project_short_name" VARCHAR(16777216),
	"case_barcode" VARCHAR(16777216),
	"primary_site" VARCHAR(16777216),
	"Hugo_Symbol" VARCHAR(16777216),
	"Entrez_Gene_Id" NUMBER(38,0),
	"Center" VARCHAR(16777216),
	"NCBI_Build" VARCHAR(16777216),
	"Chromosome" VARCHAR(16777216),
	"Start_Position" NUMBER(38,0),
	"End_Position" NUMBER(38,0),
	"Strand" VARCHAR(16777216),
	"Variant_Classification" VARCHAR(16777216),
	"Variant_Type" VARCHAR(16777216),
	"Reference_Allele" VARCHAR(16777216),
	"Tumor_Seq_Allele1" VARCHAR(16777216),
	"Tumor_Seq_Allele2" VARCHAR(16777216),
	"dbSNP_RS" VARCHAR(16777216),
	"dbSNP_Val_Status" VARCHAR(16777216),
	"Tumor_Aliquot_Barcode" VARCHAR(16777216),
	"Matched_Norm_Aliquot_Barcode" VARCHAR(16777216),
	"Match_Norm_Seq_Allele1" VARCHAR(16777216),
	"Match_Norm_Seq_Allele2" VARCHAR(16777216),
	"Tumor_Validation_Allele1" VARCHAR(16777216),
	"Tumor_Validation_Allele2" VARCHAR(16777216),
	"Match_Norm_Validation_Allele1" VARCHAR(16777216),
	"Match_Norm_Validation_Allele2" VARCHAR(16777216),
	"Verification_Status" VARCHAR(16777216),
	"Validation_Status" VARCHAR(16777216),
	"Mutation_Status" VARCHAR(16777216),
	"Sequencing_Phase" VARCHAR(16777216),
	"Sequence_Source" VARCHAR(16777216),
	"Validation_Method" VARCHAR(16777216),
	"Score" VARCHAR(16777216),
	"BAM_File" VARCHAR(16777216),
	"Sequencer" VARCHAR(16777216),
	"Tumor_Aliquot_UUID" VARCHAR(16777216),
	"Matched_Norm_Aliquot_UUID" VARCHAR(16777216),
	"HGVSc" VARCHAR(16777216),
	"HGVSp" VARCHAR(16777216),
	"HGVSp_Short" VARCHAR(16777216),
	"Transcript_ID" VARCHAR(16777216),
	"Exon_Number" VARCHAR(16777216),
	"t_depth" NUMBER(38,0),
	"t_ref_count" NUMBER(38,0),
	"t_alt_count" NUMBER(38,0),
	"n_depth" NUMBER(38,0),
	"n_ref_count" VARCHAR(16777216),
	"n_alt_count" VARCHAR(16777216),
	"all_effects" VARCHAR(16777216),
	"Allele" VARCHAR(16777216),
	"Gene" VARCHAR(16777216),
	"Feature" VARCHAR(16777216),
	"Feature_type" VARCHAR(16777216),
	"One_Consequence" VARCHAR(16777216),
	"Consequence" VARCHAR(16777216),
	"cDNA_position" VARCHAR(16777216),
	"CDS_position" VARCHAR(16777216),
	"Protein_position" VARCHAR(16777216),
	"Amino_acids" VARCHAR(16777216),
	"Codons" VARCHAR(16777216),
	"Existing_variation" VARCHAR(16777216),
	DISTANCE VARCHAR(16777216),
	TRANSCRIPT_STRAND VARCHAR(16777216),
	SYMBOL VARCHAR(16777216),
	SYMBOL_SOURCE VARCHAR(16777216),
	HGNC_ID VARCHAR(16777216),
	BIOTYPE VARCHAR(16777216),
	CANONICAL VARCHAR(16777216),
	CCDS VARCHAR(16777216),
	ENSP VARCHAR(16777216),
	SWISSPROT VARCHAR(16777216),
	TREMBL VARCHAR(16777216),
	UNIPARC VARCHAR(16777216),
	UNIPROT_ISOFORM VARCHAR(16777216),
	"RefSeq" VARCHAR(16777216),
	MANE VARCHAR(16777216),
	APPRIS VARCHAR(16777216),
	FLAGS VARCHAR(16777216),
	SIFT VARCHAR(16777216),
	"PolyPhen" VARCHAR(16777216),
	EXON VARCHAR(16777216),
	INTRON VARCHAR(16777216),
	DOMAINS VARCHAR(16777216),
	"ThousG_AF" FLOAT,
	"ThousG_AFR_AF" FLOAT,
	"ThousG_AMR_AF" FLOAT,
	"ThousG_EAS_AF" FLOAT,
	"ThousG_EUR_AF" FLOAT,
	"ThousG_SAS_AF" FLOAT,
	ESP_AA_AF FLOAT,
	ESP_EA_AF FLOAT,
	"gnomAD_AF" FLOAT,
	"gnomAD_AFR_AF" FLOAT,
	"gnomAD_AMR_AF" FLOAT,
	"gnomAD_ASJ_AF" FLOAT,
	"gnomAD_EAS_AF" FLOAT,
	"gnomAD_FIN_AF" FLOAT,
	"gnomAD_NFE_AF" FLOAT,
	"gnomAD_OTH_AF" FLOAT,
	"gnomAD_SAS_AF" FLOAT,
	MAX_AF FLOAT,
	MAX_AF_POPS VARCHAR(16777216),
	"gnomAD_non_cancer_AF" FLOAT,
	"gnomAD_non_cancer_AFR_AF" FLOAT,
	"gnomAD_non_cancer_AMI_AF" FLOAT,
	"gnomAD_non_cancer_AMR_AF" FLOAT,
	"gnomAD_non_cancer_ASJ_AF" FLOAT,
	"gnomAD_non_cancer_EAS_AF" FLOAT,
	"gnomAD_non_cancer_FIN_AF" FLOAT,
	"gnomAD_non_cancer_MID_AF" FLOAT,
	"gnomAD_non_cancer_NFE_AF" FLOAT,
	"gnomAD_non_cancer_OTH_AF" FLOAT,
	"gnomAD_non_cancer_SAS_AF" FLOAT,
	"gnomAD_non_cancer_MAX_AF_adj" FLOAT,
	"gnomAD_non_cancer_MAX_AF_POPS_adj" VARCHAR(16777216),
	CLIN_SIG VARCHAR(16777216),
	SOMATIC VARCHAR(16777216),
	PUBMED VARCHAR(16777216),
	TRANSCRIPTION_FACTORS VARCHAR(16777216),
	MOTIF_NAME VARCHAR(16777216),
	MOTIF_POS VARCHAR(16777216),
	HIGH_INF_POS VARCHAR(16777216),
	MOTIF_SCORE_CHANGE VARCHAR(16777216),
	"miRNA" VARCHAR(16777216),
	IMPACT VARCHAR(16777216),
	PICK VARCHAR(16777216),
	VARIANT_CLASS VARCHAR(16777216),
	TSL VARCHAR(16777216),
	HGVS_OFFSET VARCHAR(16777216),
	PHENO VARCHAR(16777216),
	GENE_PHENO VARCHAR(16777216),
	CONTEXT VARCHAR(16777216),
	"tumor_submitter_uuid" VARCHAR(16777216),
	"normal_submitter_uuid" VARCHAR(16777216),
	"case_id" VARCHAR(16777216),
	GDC_FILTER VARCHAR(16777216),
	COSMIC VARCHAR(16777216),
	"hotspot" BOOLEAN,
	"RNA_Support" VARCHAR(16777216),
	"RNA_depth" VARCHAR(16777216),
	"RNA_ref_count" VARCHAR(16777216),
	"RNA_alt_count" VARCHAR(16777216),
	"callers" VARCHAR(16777216),
	"file_gdc_id" VARCHAR(16777216),
	"muse" VARCHAR(16777216),
	"mutect2" VARCHAR(16777216),
	"pindel" VARCHAR(16777216),
	"varscan2" VARCHAR(16777216),
	"sample_barcode_tumor" VARCHAR(16777216),
	"sample_barcode_normal" VARCHAR(16777216),
	"aliquot_barcode_tumor" VARCHAR(16777216),
	"aliquot_barcode_normal" VARCHAR(16777216)
);

INSERT INTO "TCGA_MITELMAN"."TCGA_VERSIONED"."MASKED_SOMATIC_MUTATION_HG38_GDC_R39" (dbSNP_RS, tumor_submitter_uuid, CCDS, hotspot, COSMIC, GDC_FILTER, n_alt_count, UNIPARC, Score, aliquot_barcode_normal, Allele, t_alt_count, Matched_Norm_Aliquot_Barcode, RNA_Support, muse, One_Consequence, gnomAD_non_cancer_FIN_AF, n_depth, ESP_AA_AF, gnomAD_non_cancer_SAS_AF, SOMATIC, ThousG_EAS_AF, MAX_AF_POPS, t_depth, gnomAD_NFE_AF, miRNA, Validation_Method, PICK, Matched_Norm_Aliquot_UUID, HGNC_ID, t_ref_count, dbSNP_Val_Status, Tumor_Seq_Allele2, HGVS_OFFSET, case_barcode, gnomAD_AF, RNA_depth, Gene, BIOTYPE, Variant_Type, End_Position, gnomAD_AMR_AF, gnomAD_non_cancer_ASJ_AF, RNA_ref_count, GENE_PHENO, Tumor_Validation_Allele2, CDS_position, EXON, MOTIF_SCORE_CHANGE, PolyPhen, Start_Position, gnomAD_non_cancer_MAX_AF_POPS_adj, HGVSp_Short, Sequence_Source, Exon_Number, gnomAD_EAS_AF, pindel, Tumor_Aliquot_UUID, sample_barcode_normal, primary_site, gnomAD_non_cancer_AMR_AF, Validation_Status, Codons, Verification_Status, all_effects, RefSeq, HIGH_INF_POS, file_gdc_id, CLIN_SIG, BAM_File, Tumor_Validation_Allele1, ESP_EA_AF, FLAGS, Consequence, project_short_name, ThousG_SAS_AF, Protein_position, NCBI_Build, mutect2, Variant_Classification, ENSP, TREMBL, HGVSc, ThousG_AMR_AF, Match_Norm_Seq_Allele2, TRANSCRIPTION_FACTORS, Amino_acids, cDNA_position, Entrez_Gene_Id, case_id, normal_submitter_uuid, Existing_variation, ThousG_AFR_AF, Match_Norm_Validation_Allele2, APPRIS, MOTIF_POS, TSL, aliquot_barcode_tumor, Tumor_Seq_Allele1, gnomAD_non_cancer_AF, gnomAD_non_cancer_EAS_AF, INTRON, Match_Norm_Seq_Allele1, gnomAD_non_cancer_MAX_AF_adj, Feature, Center, gnomAD_FIN_AF, RNA_alt_count, DISTANCE, n_ref_count, CANONICAL, TRANSCRIPT_STRAND, SYMBOL, Hugo_Symbol, varscan2, MANE, Reference_Allele, PHENO, HGVSp, gnomAD_non_cancer_NFE_AF, SYMBOL_SOURCE, Sequencing_Phase, SIFT, UNIPROT_ISOFORM, Feature_type, VARIANT_CLASS, MOTIF_NAME, gnomAD_SAS_AF, CONTEXT, MAX_AF, gnomAD_AFR_AF, Mutation_Status, gnomAD_non_cancer_OTH_AF, gnomAD_ASJ_AF, IMPACT, Strand, sample_barcode_tumor, Tumor_Aliquot_Barcode, gnomAD_non_cancer_AFR_AF, gnomAD_OTH_AF, ThousG_EUR_AF, Match_Norm_Validation_Allele1, Sequencer, SWISSPROT, Transcript_ID, ThousG_AF, Chromosome, PUBMED, callers, gnomAD_non_cancer_AMI_AF, DOMAINS, gnomAD_non_cancer_MID_AF) VALUES ('rs1216625496', 'c0fab472-3cdc-4661-9010-60fa3b738ed6', 'CCDS47729.1', False, NULL, NULL, NULL, 'UPI00000620BE', NULL, 'TCGA-04-1360-11A-01W-0492-08', 'A', 165, 'TCGA-04-1360-11A-01W-0492-08', 'Unknown', 'Yes', 'synonymous_variant', nan, 613, NULL, nan, '0;1', NULL, 'gnomAD_SAS', 1146, 0.0, NULL, NULL, '1', '7019adc7-8cd6-4942-9cfd-39cdbc19f283', 'HGNC:18886', 981, NULL, 'A', NULL, 'TCGA-04-1360', 4.012e-06, NULL, 'ENSG00000236398', 'protein_coding', 'SNP', 143184183, 0.0, nan, NULL, NULL, NULL, '765/1017', '1/1', NULL, NULL, 143184183, NULL, 'p.E255=', NULL, '1/1', 0.0, 'No', '0c2c84b0-43e2-469c-8813-f50f2599d90f', 'TCGA-04-1360-11A', 'Ovary', nan, NULL, 'gaG/gaA', NULL, 'TAS2R39,synonymous_variant,p.E255=,ENST00000446620,NM_176881.2,c.765G>A,LOW,YES,,,1', 'NM_176881.2', NULL, '434bd7d8-91fb-44f5-8e1e-975963a6b733', NULL, NULL, NULL, NULL, NULL, 'synonymous_variant', 'TCGA-OV', NULL, '255/338', 'GRCh38', 'Yes', 'Silent', 'ENSP00000405095', NULL, 'c.765G>A', NULL, NULL, NULL, 'E', '765/1017', 259285, 'e0502c47-3234-4609-a8d5-730a9e6eb5b8', '0651c598-5bd2-42b7-942b-0fc1fd070d35', 'rs1216625496;COSV101489421', NULL, NULL, 'P1', NULL, NULL, 'TCGA-04-1360-01A-01W-0492-08', 'G', nan, nan, NULL, NULL, nan, 'ENST00000446620', 'BI', 0.0, NULL, NULL, NULL, 'YES', '1', 'TAS2R39', 'TAS2R39', 'Yes', 'NM_176881.2', 'G', '0;1', 'p.Glu255=', nan, 'HGNC', NULL, NULL, NULL, 'Transcript', 'SNV', NULL, 3.268e-05, 'ATGGAGGCTCA', 3.268e-05, 0.0, 'Somatic', nan, 0.0, 'LOW', '+', 'TCGA-04-1360-01A', 'TCGA-04-1360-01A-01W-0492-08', nan, 0.0, NULL, NULL, NULL, 'P59534.133', 'ENST00000446620', NULL, 'chr7', NULL, 'muse;mutect2;varscan2', nan, 'CDD:cd15015;PANTHER:PTHR11394:SF136;PANTHER:PTHR11394;Pfam:PF05296;Superfamily:SSF81321', nan), ('rs1321965561', '1e4437dd-6049-4a7d-8102-594316f14efa', 'CCDS1014.1', False, NULL, NULL, NULL, 'UPI000006EC48', NULL, 'TCGA-04-1369-11A-01D-1526-09', 'T', 11, 'TCGA-04-1369-11A-01D-1526-09', 'Unknown', 'Yes', 'missense_variant', 0.0, 220, NULL, 0.0, '0;1', NULL, 'gnomAD_AFR', 171, 0.0, NULL, NULL, '1', 'e1d50578-4839-4490-ab36-f0d82fec4eec', 'HGNC:16615', 160, NULL, 'T', NULL, 'TCGA-04-1369', 3.983e-06, NULL, 'ENSG00000163202', 'protein_coding', 'SNP', 152579717, 0.0, 0.0, NULL, NULL, NULL, '220/279', '2/2', NULL, 'possibly_damaging(0.764)', 152579717, 'afr', 'p.G74S', NULL, '2/2', 0.0, 'No', '7a657ef6-0ff3-40cb-b02b-a1a79ef899f6', 'TCGA-04-1369-11A', 'Ovary', 0.0, NULL, 'Ggc/Agc', NULL, 'LCE3D,missense_variant,p.G74S,ENST00000368787,NM_032563.2,c.220G>A,MODERATE,YES,deleterious_low_confidence(0.03),possibly_damaging(0.764),-1', 'NM_032563.2', NULL, '7f5e52cd-7481-4e75-9826-8fb59cbc413b', NULL, NULL, NULL, NULL, NULL, 'missense_variant', 'TCGA-OV', NULL, '74/92', 'GRCh38', 'Yes', 'Missense_Mutation', 'ENSP00000357776', NULL, 'c.220G>A', NULL, NULL, NULL, 'G/S', '289/625', 84648, '6c43727d-631a-40fb-b1a1-242a12889eaa', 'f1798146-9940-463d-9144-3393c88c2001', 'rs1321965561;COSV100909856', NULL, NULL, 'P1', NULL, '1', 'TCGA-04-1369-01A-02D-1526-09', 'C', 1.3528099771065172e-05, 0.0, NULL, NULL, 4.8626301577314734e-05, 'ENST00000368787', 'WUGSC', 0.0, NULL, NULL, NULL, 'YES', '-1', 'LCE3D', 'LCE3D', 'No', 'NM_032563.2', 'C', '0;1', 'p.Gly74Ser', 0.0, 'HGNC', NULL, 'deleterious_low_confidence(0.03)', NULL, 'Transcript', 'SNV', NULL, 0.0, 'ACTGCCCCTGT', 6.193e-05, 6.193e-05, 'Somatic', 0.0, 0.0, 'MODERATE', '+', 'TCGA-04-1369-01A', 'TCGA-04-1369-01A-02D-1526-09', 4.8626301577314734e-05, 0.0, NULL, NULL, NULL, 'Q9BYE3.103', 'ENST00000368787', NULL, 'chr1', NULL, 'muse;mutect2', 0.0, 'Pfam:PF14672;PANTHER:PTHR23263;PANTHER:PTHR23263:SF123;MobiDB_lite:mobidb-lite;Low_complexity_(Seg):seg', 0.0), ('rs1347456083', '060c15c0-25ca-4464-8aa3-364396b9b34c', 'CCDS3074.1', False, NULL, NULL, NULL, 'UPI0000223E4E', NULL, 'TCGA-05-4382-10A-01D-1265-08', 'T', 17, 'TCGA-05-4382-10A-01D-1265-08', 'Unknown', 'Yes', 'missense_variant', nan, 86, NULL, nan, '0;1', NULL, 'gnomAD_SAS', 160, 0.0, NULL, NULL, '1', '20e316a4-d1e4-44d2-881c-527e600203f0', 'HGNC:30211', 143, NULL, 'T', NULL, 'TCGA-05-4382', 3.983e-06, NULL, 'ENSG00000240303', 'protein_coding', 'SNP', 132642118, 0.0, nan, NULL, NULL, NULL, '391/2343', '4/20', NULL, 'benign(0.207)', 132642118, NULL, 'p.D131N', NULL, '4/20', 0.0, 'No', '43b8f335-bb32-45de-985a-85508048b237', 'TCGA-05-4382-10A', 'Bronchus and lung', nan, NULL, 'Gat/Aat', NULL, 'ACAD11,missense_variant,p.D131N,ENST00000264990,NM_032169.5,c.391G>A,MODERATE,YES,deleterious(0.04),benign(0.207),-1;ACAD11,missense_variant,p.D131N,ENST00000481970,,c.391G>A,MODERATE,,tolerated(0.05),benign(0.422),-1;NPHP3-ACAD11,downstream_gene_variant,,ENST00000632629,,,MODIFIER,YES,,,-1;ACAD11,intron_variant,,ENST00000489991,,n.461-11560G>A,MODIFIER,,,,-1;ACAD11,missense_variant,p.D131N,ENST00000485198,,c.391G>A,MODERATE,,deleterious(0.03),benign(0.422),-1;NPHP3-ACAD11,3_prime_UTR_variant,,ENST00000471702,,c.*2217G>A,MODIFIER,,,,-1;ACAD11,non_coding_transcript_exon_variant,,ENST00000496418,,n.289G>A,MODIFIER,,,,-1;ACAD11,non_coding_transcript_exon_variant,,ENST00000469042,,n.722G>A,MODIFIER,,,,-1;HSPA8P19,upstream_gene_variant,,ENST00000505359,,,MODIFIER,YES,,,1', 'NM_032169.5', NULL, '879297cc-5afe-48aa-9a38-e8b1c6fe0a32', NULL, NULL, NULL, NULL, NULL, 'missense_variant', 'TCGA-LUAD', NULL, '131/780', 'GRCh38', 'Yes', 'Missense_Mutation', 'ENSP00000264990', NULL, 'c.391G>A', NULL, NULL, NULL, 'D/N', '449/3231', 84129, '3434b91a-c05f-460f-a078-7b1bb6e7085d', 'f0be1c9e-728c-4655-b792-96bfe1cd5344', 'rs1347456083;COSV99391730', NULL, NULL, 'P1', NULL, '1', 'TCGA-05-4382-01A-01D-1931-08', 'C', nan, nan, NULL, NULL, nan, 'ENST00000264990', 'BI', 0.0, NULL, NULL, NULL, 'YES', '-1', 'ACAD11', 'ACAD11', 'Yes', 'NM_032169.5', 'C', '0;1', 'p.Asp131Asn', nan, 'HGNC', NULL, 'deleterious(0.04)', 'Q709F0-1', 'Transcript', 'SNV', NULL, 3.268e-05, 'TAAATCACGGA', 3.268e-05, 0.0, 'Somatic', nan, 0.0, 'MODERATE', '+', 'TCGA-05-4382-01A', 'TCGA-05-4382-01A-01D-1931-08', nan, 0.0, NULL, NULL, NULL, 'Q709F0.150', 'ENST00000264990', NULL, 'chr3', NULL, 'muse;mutect2;varscan2', nan, 'CDD:cd05154;PANTHER:PTHR45741;Gene3D:3.90.1200.10;Pfam:PF01636;Superfamily:SSF56112', nan), ('rs768323927', '25f239bb-883f-44bf-88c2-3977503a5321', 'CCDS43789.1', False, 'COSM6115218;COSM6115219', NULL, NULL, 'UPI0000458809', NULL, 'TCGA-05-4396-10A-01D-1855-08', 'G', 120, 'TCGA-05-4396-10A-01D-1855-08', 'Unknown', 'Yes', 'missense_variant', 0.0, 200, NULL, 0.0, '0;1', NULL, 'gnomAD_NFE', 186, 1.11e-05, NULL, NULL, '1', '1f8820d1-4a97-41b7-a4d8-be832c9e0575', 'HGNC:23432', 66, NULL, 'G', NULL, 'TCGA-05-4396', 5.609e-06, NULL, 'ENSG00000044459', 'protein_coding', 'SNP', 17464547, 0.0, 0.0, NULL, NULL, NULL, '3455/4221', '21/26', NULL, 'probably_damaging(0.935)', 17464547, NULL, 'p.D1152G', NULL, '21/26', 0.0, 'No', '0176cf1d-0760-4769-a493-277f4bb7585e', 'TCGA-05-4396-10A', 'Bronchus and lung', 0.0, NULL, 'gAc/gGc', NULL, 'CNTLN,missense_variant,p.D1152G,ENST00000380647,NM_017738.4&NM_001365029.1,c.3455A>G,MODERATE,YES,deleterious(0.01),probably_damaging(0.935),1;CNTLN,downstream_gene_variant,,ENST00000461247,,,MODIFIER,,,,1', 'NM_017738.4;NM_001365029.1', NULL, 'bc70453f-1898-4235-95d2-bb163a09d767', NULL, NULL, NULL, NULL, NULL, 'missense_variant', 'TCGA-LUAD', NULL, '1152/1406', 'GRCh38', 'Yes', 'Missense_Mutation', 'ENSP00000370021', NULL, 'c.3455A>G', NULL, NULL, NULL, 'D/G', '3481/5518', 54875, '9f81c602-8afa-4588-b0b6-6e5a1a128d5a', '69e9e6eb-f053-4285-a66e-2e12216d6893', 'rs768323927;COSV52099260', NULL, NULL, 'P2', NULL, '1', 'TCGA-05-4396-01A-21D-1855-08', 'A', 6.822860086685978e-06, 0.0, NULL, NULL, nan, 'ENST00000380647', 'BI', 0.0, NULL, NULL, NULL, 'YES', '1', 'CNTLN', 'CNTLN', 'Yes', 'NM_017738.4', 'A', '0;1', 'p.Asp1152Gly', 1.5618699762853794e-05, 'HGNC', NULL, 'deleterious(0.01)', 'Q9NXG0-2', 'Transcript', 'SNV', NULL, 0.0, 'AGAGGACTTGA', 1.11e-05, 0.0, 'Somatic', 0.0, 0.0, 'MODERATE', '+', 'TCGA-05-4396-01A', 'TCGA-05-4396-01A-21D-1855-08', 0.0, 0.0, NULL, NULL, NULL, 'Q9NXG0.136', 'ENST00000380647', NULL, 'chr9', NULL, 'muse;mutect2;varscan2', 0.0, 'PANTHER:PTHR18957', 0.0), ('rs774702840', 'b9f53be3-dd39-425a-bc30-b9175c3ba470', 'CCDS46919.1', False, 'COSM6096154;COSM6096155', NULL, NULL, 'UPI000020A292', NULL, 'TCGA-05-4403-10A-01D-1265-08', 'A', 7, 'TCGA-05-4403-10A-01D-1265-08', 'Unknown', 'Yes', 'missense_variant', 0.0, 100, NULL, 0.0, '0;1', NULL, 'gnomAD_EAS', 50, 0.0, NULL, NULL, '1', 'a17b5d32-f570-4d2d-9e97-f8b01de1be9f', 'HGNC:17008', 43, NULL, 'A', NULL, 'TCGA-05-4403', 8.033e-06, NULL, 'ENSG00000163781', 'protein_coding', 'SNP', 133644096, 2.903e-05, 0.0, NULL, NULL, NULL, '1772/4569', '11/28', NULL, 'benign(0.362)', 133644096, 'amr', 'p.A591V', NULL, '11/28', 5.564e-05, 'No', '7e25ac0e-94e4-42f6-ae6f-89d0d21ce09f', 'TCGA-05-4403-10A', 'Bronchus and lung', 0.00019878099556080997, NULL, 'gCg/gTg', NULL, 'TOPBP1,missense_variant,p.A586V,ENST00000642236,NM_001363889.2,c.1757C>T,MODERATE,,deleterious(0.02),benign(0.286),-1;TOPBP1,missense_variant,p.A591V,ENST00000260810,NM_007027.4,c.1772C>T,MODERATE,YES,deleterious(0.02),benign(0.362),-1;TOPBP1,downstream_gene_variant,,ENST00000511439,,,MODIFIER,,,,-1;TOPBP1,downstream_gene_variant,,ENST00000509162,,,MODIFIER,,,,-1', 'NM_007027.4', NULL, '9ff327bf-3a69-4255-9504-10d14725eeb4', NULL, NULL, NULL, NULL, NULL, 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