-- DBMS: snowflake
create or replace TABLE MASKED_SOMATIC_MUTATION_HG38_GDC_R36 (
	"project_short_name" VARCHAR(16777216),
	"case_barcode" VARCHAR(16777216),
	"primary_site" VARCHAR(16777216),
	"Hugo_Symbol" VARCHAR(16777216),
	"Entrez_Gene_Id" NUMBER(38,0),
	"Center" VARCHAR(16777216),
	"NCBI_Build" VARCHAR(16777216),
	"Chromosome" VARCHAR(16777216),
	"Start_Position" NUMBER(38,0),
	"End_Position" NUMBER(38,0),
	"Strand" VARCHAR(16777216),
	"Variant_Classification" VARCHAR(16777216),
	"Variant_Type" VARCHAR(16777216),
	"Reference_Allele" VARCHAR(16777216),
	"Tumor_Seq_Allele1" VARCHAR(16777216),
	"Tumor_Seq_Allele2" VARCHAR(16777216),
	"dbSNP_RS" VARCHAR(16777216),
	"dbSNP_Val_Status" VARCHAR(16777216),
	"Tumor_Aliquot_Barcode" VARCHAR(16777216),
	"Matched_Norm_Aliquot_Barcode" VARCHAR(16777216),
	"Match_Norm_Seq_Allele1" VARCHAR(16777216),
	"Match_Norm_Seq_Allele2" VARCHAR(16777216),
	"Tumor_Validation_Allele1" VARCHAR(16777216),
	"Tumor_Validation_Allele2" VARCHAR(16777216),
	"Match_Norm_Validation_Allele1" VARCHAR(16777216),
	"Match_Norm_Validation_Allele2" VARCHAR(16777216),
	"Verification_Status" VARCHAR(16777216),
	"Validation_Status" VARCHAR(16777216),
	"Mutation_Status" VARCHAR(16777216),
	"Sequencing_Phase" VARCHAR(16777216),
	"Sequence_Source" VARCHAR(16777216),
	"Validation_Method" VARCHAR(16777216),
	"Score" VARCHAR(16777216),
	"BAM_File" VARCHAR(16777216),
	"Sequencer" VARCHAR(16777216),
	"Tumor_Aliquot_UUID" VARCHAR(16777216),
	"Matched_Norm_Aliquot_UUID" VARCHAR(16777216),
	"HGVSc" VARCHAR(16777216),
	"HGVSp" VARCHAR(16777216),
	"HGVSp_Short" VARCHAR(16777216),
	"Transcript_ID" VARCHAR(16777216),
	"Exon_Number" VARCHAR(16777216),
	"t_depth" NUMBER(38,0),
	"t_ref_count" NUMBER(38,0),
	"t_alt_count" NUMBER(38,0),
	"n_depth" NUMBER(38,0),
	"n_ref_count" VARCHAR(16777216),
	"n_alt_count" VARCHAR(16777216),
	"all_effects" VARCHAR(16777216),
	"Allele" VARCHAR(16777216),
	"Gene" VARCHAR(16777216),
	"Feature" VARCHAR(16777216),
	"Feature_type" VARCHAR(16777216),
	"One_Consequence" VARCHAR(16777216),
	"Consequence" VARCHAR(16777216),
	"cDNA_position" VARCHAR(16777216),
	"CDS_position" VARCHAR(16777216),
	"Protein_position" VARCHAR(16777216),
	"Amino_acids" VARCHAR(16777216),
	"Codons" VARCHAR(16777216),
	"Existing_variation" VARCHAR(16777216),
	DISTANCE VARCHAR(16777216),
	TRANSCRIPT_STRAND VARCHAR(16777216),
	SYMBOL VARCHAR(16777216),
	SYMBOL_SOURCE VARCHAR(16777216),
	HGNC_ID VARCHAR(16777216),
	BIOTYPE VARCHAR(16777216),
	CANONICAL VARCHAR(16777216),
	CCDS VARCHAR(16777216),
	ENSP VARCHAR(16777216),
	SWISSPROT VARCHAR(16777216),
	TREMBL VARCHAR(16777216),
	UNIPARC VARCHAR(16777216),
	UNIPROT_ISOFORM VARCHAR(16777216),
	"RefSeq" VARCHAR(16777216),
	MANE VARCHAR(16777216),
	APPRIS VARCHAR(16777216),
	FLAGS VARCHAR(16777216),
	SIFT VARCHAR(16777216),
	"PolyPhen" VARCHAR(16777216),
	EXON VARCHAR(16777216),
	INTRON VARCHAR(16777216),
	DOMAINS VARCHAR(16777216),
	"ThousG_AF" FLOAT,
	"ThousG_AFR_AF" FLOAT,
	"ThousG_AMR_AF" FLOAT,
	"ThousG_EAS_AF" FLOAT,
	"ThousG_EUR_AF" FLOAT,
	"ThousG_SAS_AF" FLOAT,
	ESP_AA_AF FLOAT,
	ESP_EA_AF FLOAT,
	"gnomAD_AF" FLOAT,
	"gnomAD_AFR_AF" FLOAT,
	"gnomAD_AMR_AF" FLOAT,
	"gnomAD_ASJ_AF" FLOAT,
	"gnomAD_EAS_AF" FLOAT,
	"gnomAD_FIN_AF" FLOAT,
	"gnomAD_NFE_AF" FLOAT,
	"gnomAD_OTH_AF" FLOAT,
	"gnomAD_SAS_AF" FLOAT,
	MAX_AF FLOAT,
	MAX_AF_POPS VARCHAR(16777216),
	"gnomAD_non_cancer_AF" FLOAT,
	"gnomAD_non_cancer_AFR_AF" FLOAT,
	"gnomAD_non_cancer_AMI_AF" FLOAT,
	"gnomAD_non_cancer_AMR_AF" FLOAT,
	"gnomAD_non_cancer_ASJ_AF" FLOAT,
	"gnomAD_non_cancer_EAS_AF" FLOAT,
	"gnomAD_non_cancer_FIN_AF" FLOAT,
	"gnomAD_non_cancer_MID_AF" FLOAT,
	"gnomAD_non_cancer_NFE_AF" FLOAT,
	"gnomAD_non_cancer_OTH_AF" FLOAT,
	"gnomAD_non_cancer_SAS_AF" FLOAT,
	"gnomAD_non_cancer_MAX_AF_adj" FLOAT,
	"gnomAD_non_cancer_MAX_AF_POPS_adj" VARCHAR(16777216),
	CLIN_SIG VARCHAR(16777216),
	SOMATIC VARCHAR(16777216),
	PUBMED VARCHAR(16777216),
	TRANSCRIPTION_FACTORS VARCHAR(16777216),
	MOTIF_NAME VARCHAR(16777216),
	MOTIF_POS VARCHAR(16777216),
	HIGH_INF_POS VARCHAR(16777216),
	MOTIF_SCORE_CHANGE VARCHAR(16777216),
	"miRNA" VARCHAR(16777216),
	IMPACT VARCHAR(16777216),
	PICK VARCHAR(16777216),
	VARIANT_CLASS VARCHAR(16777216),
	TSL VARCHAR(16777216),
	HGVS_OFFSET VARCHAR(16777216),
	PHENO VARCHAR(16777216),
	GENE_PHENO VARCHAR(16777216),
	CONTEXT VARCHAR(16777216),
	"tumor_submitter_uuid" VARCHAR(16777216),
	"normal_submitter_uuid" VARCHAR(16777216),
	"case_id" VARCHAR(16777216),
	GDC_FILTER VARCHAR(16777216),
	COSMIC VARCHAR(16777216),
	"hotspot" BOOLEAN,
	"RNA_Support" VARCHAR(16777216),
	"RNA_depth" VARCHAR(16777216),
	"RNA_ref_count" VARCHAR(16777216),
	"RNA_alt_count" VARCHAR(16777216),
	"callers" VARCHAR(16777216),
	"file_gdc_id" VARCHAR(16777216),
	"muse" VARCHAR(16777216),
	"mutect2" VARCHAR(16777216),
	"pindel" VARCHAR(16777216),
	"varscan2" VARCHAR(16777216),
	"sample_barcode_tumor" VARCHAR(16777216),
	"sample_barcode_normal" VARCHAR(16777216),
	"aliquot_barcode_tumor" VARCHAR(16777216),
	"aliquot_barcode_normal" VARCHAR(16777216)
);

INSERT INTO "TCGA"."TCGA_VERSIONED"."MASKED_SOMATIC_MUTATION_HG38_GDC_R36" (SWISSPROT, ThousG_SAS_AF, RNA_ref_count, CLIN_SIG, gnomAD_non_cancer_SAS_AF, n_alt_count, Tumor_Aliquot_UUID, Feature, RNA_alt_count, sample_barcode_tumor, MANE, Reference_Allele, PUBMED, MOTIF_SCORE_CHANGE, gnomAD_AMR_AF, Match_Norm_Validation_Allele2, SOMATIC, CDS_position, gnomAD_NFE_AF, TREMBL, case_barcode, CCDS, gnomAD_EAS_AF, gnomAD_non_cancer_AMI_AF, CONTEXT, Variant_Classification, varscan2, BIOTYPE, gnomAD_OTH_AF, Matched_Norm_Aliquot_UUID, hotspot, t_depth, pindel, Consequence, Tumor_Validation_Allele2, tumor_submitter_uuid, GDC_FILTER, gnomAD_non_cancer_MID_AF, Codons, Center, Sequence_Source, gnomAD_FIN_AF, primary_site, gnomAD_SAS_AF, t_alt_count, ThousG_AF, gnomAD_non_cancer_AFR_AF, UNIPARC, ESP_AA_AF, gnomAD_ASJ_AF, gnomAD_non_cancer_MAX_AF_POPS_adj, HGVSc, DOMAINS, MOTIF_POS, miRNA, TRANSCRIPT_STRAND, EXON, CANONICAL, Matched_Norm_Aliquot_Barcode, Existing_variation, Validation_Status, Tumor_Seq_Allele2, COSMIC, Strand, all_effects, SYMBOL, Start_Position, HGNC_ID, ThousG_EUR_AF, cDNA_position, INTRON, Variant_Type, Validation_Method, t_ref_count, Match_Norm_Seq_Allele1, PHENO, VARIANT_CLASS, HGVS_OFFSET, Entrez_Gene_Id, Tumor_Seq_Allele1, TRANSCRIPTION_FACTORS, Verification_Status, Match_Norm_Validation_Allele1, gnomAD_non_cancer_FIN_AF, gnomAD_AF, Sequencing_Phase, Feature_type, aliquot_barcode_normal, APPRIS, One_Consequence, ThousG_AMR_AF, Mutation_Status, Score, Allele, callers, n_depth, DISTANCE, gnomAD_non_cancer_EAS_AF, HGVSp_Short, Tumor_Validation_Allele1, gnomAD_non_cancer_OTH_AF, sample_barcode_normal, case_id, dbSNP_Val_Status, Sequencer, ThousG_EAS_AF, ThousG_AFR_AF, project_short_name, gnomAD_non_cancer_ASJ_AF, Protein_position, file_gdc_id, RNA_depth, MOTIF_NAME, MAX_AF_POPS, SYMBOL_SOURCE, Transcript_ID, HIGH_INF_POS, gnomAD_AFR_AF, RNA_Support, Chromosome, aliquot_barcode_tumor, gnomAD_non_cancer_AF, PolyPhen, RefSeq, gnomAD_non_cancer_AMR_AF, IMPACT, Match_Norm_Seq_Allele2, mutect2, Hugo_Symbol, Amino_acids, gnomAD_non_cancer_NFE_AF, muse, gnomAD_non_cancer_MAX_AF_adj, PICK, ENSP, BAM_File, MAX_AF, UNIPROT_ISOFORM, Gene, NCBI_Build, SIFT, dbSNP_RS, ESP_EA_AF, normal_submitter_uuid, End_Position, HGVSp, TSL, FLAGS, Tumor_Aliquot_Barcode, n_ref_count, Exon_Number, GENE_PHENO) VALUES ('Q9Y239.198', NULL, NULL, NULL, 0.0, NULL, '0332b017-17d5-4083-8fc4-9d6f8fdbbbde', 'ENST00000222823', NULL, 'TCGA-02-2485-01A', 'NM_006092.4', 'G', NULL, NULL, 0.0, NULL, '0;1', '675/2862', 8.8e-06, 'A0A024RA73.49', 'TCGA-02-2485', 'CCDS5427.1', 0.0, 0.0, 'CCTGCGTCTAG', 'Silent', 'Yes', 'protein_coding', 0.0, '8faa4b6d-6c64-4c03-bb3d-e2d33db491b0', False, 142, 'No', 'synonymous_variant', NULL, '218d3f5e-1165-45ae-b6a1-4f47774dc654', NULL, 0.0, 'gaC/gaT', 'BI', NULL, 0.0, 'Brain', 0.0, 55, NULL, 4.859789987676777e-05, 'UPI00000375EE', NULL, 0.0, 'afr', 'c.675C>T', 'Gene3D:3.40.50.300;Pfam:PF05729;PROSITE_profiles:PS50837;PANTHER:PTHR24106;PANTHER:PTHR24106:SF18', NULL, NULL, '-1', '6/14', 'YES', 'TCGA-02-2485-10A-01D-1494-08', 'rs150842987;COSV56111071', NULL, 'A', 'COSM3411972', '+', 'NOD1,synonymous_variant,p.D225=,ENST00000222823,NM_001354849.1&NM_006092.4,c.675C>T,LOW,YES,,,-1;NOD1,downstream_gene_variant,,ENST00000411552,,,MODIFIER,,,,-1;NOD1,downstream_gene_variant,,ENST00000413433,,,MODIFIER,,,,-1;NOD1,downstream_gene_variant,,ENST00000419601,,,MODIFIER,,,,-1;NOD1,downstream_gene_variant,,ENST00000419799,,,MODIFIER,,,,-1;NOD1,synonymous_variant,p.D225=,ENST00000434755,,c.675C>T,LOW,,,,-1;NOD1,upstream_gene_variant,,ENST00000489614,,,MODIFIER,,,,-1', 'NOD1', 30452742, 'HGNC:16390', NULL, '1205/4503', NULL, 'SNP', NULL, 85, NULL, '0;1', 'SNV', NULL, 10392, 'G', NULL, NULL, NULL, 0.0, 7.959e-06, NULL, 'Transcript', 'TCGA-02-2485-10A-01D-1494-08', 'P1', 'synonymous_variant', NULL, 'Somatic', NULL, 'A', 'muse;mutect2;varscan2', 122, NULL, 0.0, 'p.D225=', NULL, 0.0, 'TCGA-02-2485-10A', '521ea765-1bd1-423d-a75d-091243df37a9', NULL, NULL, NULL, NULL, 'TCGA-GBM', 0.0, '225/953', '6f560343-1ad3-4e32-a581-a6871b6fa612', NULL, NULL, 'gnomAD_AFR', 'HGNC', 'ENST00000222823', NULL, 6.156e-05, 'Unknown', 'chr7', 'TCGA-02-2485-01A-01D-1494-08', 1.351549963146681e-05, NULL, 'NM_001354849.1;NM_006092.4', 0.0, 'LOW', NULL, 'Yes', 'NOD1', 'D', 0.0, 'Yes', 4.859789987676777e-05, '1', 'ENSP00000222823', NULL, 6.156e-05, 'Q9Y239-1', 'ENSG00000106100', 'GRCh38', NULL, 'rs150842987', NULL, 'abf8ec28-0d54-41d3-9e6b-1c367406bd07', 30452742, 'p.Asp225=', '1', NULL, 'TCGA-02-2485-01A-01D-1494-08', NULL, '6/14', NULL), ('Q8NHM5.173', NULL, NULL, NULL, nan, NULL, '3331813c-f538-4833-b5eb-a214b7d52334', 'ENST00000377071', NULL, 'TCGA-02-2486-01A', 'NM_032590.5', 'C', NULL, NULL, 0.0, NULL, '0;1', '2944/4011', 9.371e-06, NULL, 'TCGA-02-2486', 'CCDS41850.1', 0.0, nan, 'CTCCTCGCCCT', 'Missense_Mutation', 'Yes', 'protein_coding', 0.0, '334697ef-d664-4d24-9ddb-c4d7448fd00d', False, 77, 'No', 'missense_variant', NULL, 'd5b9408d-e95e-41d5-b1de-8dd6e50b572b', NULL, nan, 'Gag/Aag', 'BI', NULL, 0.0, 'Brain', 0.0, 20, NULL, nan, 'UPI000006F36E', NULL, 0.0, NULL, 'c.2944G>A', 'Low_complexity_(Seg):seg;MobiDB_lite:mobidb-lite;MobiDB_lite:mobidb-lite;PANTHER:PTHR23123;PANTHER:PTHR23123:SF10', NULL, NULL, '-1', '19/23', 'YES', 'TCGA-02-2486-10A-01D-1494-08', 'rs782132082;COSV65640263', NULL, 'T', 'COSM3398446;COSM3398447;COSM3398448', '+', 'KDM2B,missense_variant,p.E982K,ENST00000377071,NM_032590.5,c.2944G>A,MODERATE,YES,deleterious_low_confidence(0.02),benign(0.023),-1;KDM2B,missense_variant,p.E913K,ENST00000377069,NM_001005366.2,c.2737G>A,MODERATE,,deleterious(0.01),benign(0.191),-1;KDM2B,missense_variant,p.E350K,ENST00000542973,,c.1048G>A,MODERATE,,deleterious(0.05),benign(0.023),-1;KDM2B,intron_variant,,ENST00000536437,,c.2104-2624G>A,MODIFIER,,,,-1;KDM2B,intron_variant,,ENST00000611216,,c.1608+10623G>A,MODIFIER,,,,-1;MIR7107,downstream_gene_variant,,ENST00000611489,,,MODIFIER,YES,,,-1;KDM2B,non_coding_transcript_exon_variant,,ENST00000538503,,n.4090G>A,MODIFIER,,,,-1;KDM2B,intron_variant,,ENST00000543025,,c.*1565+10623G>A,MODIFIER,,,,-1;KDM2B,upstream_gene_variant,,ENST00000536036,,,MODIFIER,,,,-1;KDM2B,downstream_gene_variant,,ENST00000538243,,,MODIFIER,,,,-1', 'KDM2B', 121442497, 'HGNC:13610', NULL, '3056/5315', NULL, 'SNP', NULL, 56, NULL, '0;1', 'SNV', NULL, 84678, 'C', NULL, NULL, NULL, nan, 4.328e-06, NULL, 'Transcript', 'TCGA-02-2486-10A-01D-1494-08', 'P4', 'missense_variant', NULL, 'Somatic', NULL, 'T', 'muse;mutect2;varscan2', 55, NULL, nan, 'p.E982K', NULL, nan, 'TCGA-02-2486-10A', '79a68b32-29a3-47bf-9b2b-643ec7323d73', NULL, NULL, NULL, NULL, 'TCGA-GBM', nan, '982/1336', '523e6728-6954-4f10-9ca3-2beb93a00eaa', NULL, NULL, 'gnomAD_NFE', 'HGNC', 'ENST00000377071', NULL, 0.0, 'Unknown', 'chr12', 'TCGA-02-2486-01A-01D-1494-08', nan, 'benign(0.023)', 'NM_032590.5', nan, 'MODERATE', NULL, 'Yes', 'KDM2B', 'E/K', nan, 'Yes', nan, '1', 'ENSP00000366271', NULL, 9.371e-06, 'Q8NHM5-1', 'ENSG00000089094', 'GRCh38', 'deleterious_low_confidence(0.02)', 'rs782132082', NULL, '33685a0d-5a70-414c-969e-dfedfeb714a8', 121442497, 'p.Glu982Lys', '1', NULL, 'TCGA-02-2486-01A-01D-1494-08', NULL, '19/23', NULL), ('O43298.178', NULL, NULL, NULL, 0.0, NULL, '21b50b8c-781a-4e15-a4ad-715f416f0fa2', 'ENST00000373457', NULL, 'TCGA-04-1347-01A', NULL, 'C', NULL, NULL, 5.794e-05, NULL, '0;1', '1362/1404', 2.687e-05, NULL, 'TCGA-04-1347', 'CCDS6867.1', 0.0, 0.0, 'TCCTACGAAGC', 'Silent', 'Yes', 'protein_coding', 0.0, '36e22642-4216-43dd-a3fc-52310081f5e0', False, 164, 'No', 'synonymous_variant', NULL, '07b787e5-0af6-4b06-adf7-a5c486400107', NULL, 0.0, 'taC/taT', 'BI;WUGSC', NULL, 0.0, 'Ovary', 0.0, 39, NULL, 4.870209886576049e-05, 'UPI000013C34F', NULL, 0.0, 'oth', 'c.1362C>T', 'PDB-ENSP_mappings:2csh.A;PROSITE_profiles:PS50157;PANTHER:PTHR24414:SF43;PANTHER:PTHR24414;Gene3D:3.30.160.60', NULL, NULL, '1', '1/1', NULL, 'TCGA-04-1347-11A-01W-0487-08', 'rs776691831;COSV65094390', NULL, 'T', 'COSM81930', '+', 'ZBTB43,synonymous_variant,p.Y454=,ENST00000373464,NM_014007.4,c.1362C>T,LOW,YES,,,1;ZBTB43,synonymous_variant,p.Y454=,ENST00000449886,NM_001135776.1,c.1362C>T,LOW,,,,1;ZBTB43,synonymous_variant,p.Y454=,ENST00000373457,,c.1362C>T,LOW,,,,1;ZBTB43,downstream_gene_variant,,ENST00000450858,,,MODIFIER,,,,1;ZBTB43,upstream_gene_variant,,ENST00000497064,,,MODIFIER,,,,1', 'ZBTB43', 126833871, 'HGNC:17908', NULL, '2463/5695', NULL, 'SNP', NULL, 125, NULL, '0;1', 'SNV', NULL, 23099, 'C', NULL, NULL, NULL, 0.0, 2.015e-05, NULL, 'Transcript', 'TCGA-04-1347-11A-01W-0487-08', 'P1', 'synonymous_variant', NULL, 'Somatic', NULL, 'T', 'muse;mutect2;varscan2', 331, NULL, 0.0, 'p.Y454=', NULL, 0.000991079956293106, 'TCGA-04-1347-11A', 'f0c353fd-947c-41e2-b643-3ecc0d69796c', NULL, NULL, NULL, NULL, 'TCGA-OV', 0.0, '454/467', '818dbf34-acb1-4f65-bb95-bd00971f9179', NULL, NULL, 'gnomAD_AMR', 'HGNC', 'ENST00000373457', NULL, 0.0, 'Unknown', 'chr9', 'TCGA-04-1347-01A-01W-0488-09', 4.059320053784177e-05, NULL, NULL, 0.0, 'LOW', NULL, 'Yes', 'ZBTB43', 'Y', 3.0868999601807445e-05, 'Yes', 0.000991079956293106, NULL, 'ENSP00000362556', NULL, 5.794e-05, NULL, 'ENSG00000169155', 'GRCh38', NULL, 'rs776691831', NULL, '894c0a3e-aaa1-4768-92ae-3e802d7c74e2', 126833871, 'p.Tyr454=', NULL, NULL, 'TCGA-04-1347-01A-01W-0488-09', NULL, '1/1', NULL), ('P27797.238', NULL, NULL, NULL, nan, NULL, 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