niryuu/sni-each-converted huggingface dataset:
Nearly a quarter century after a German boy threw a message in a bottle off a ship in the Baltic Sea, he's received an answer. A 13yearold Russian, Daniil Korotkikh, was walking with his parents on a beach when he saw something lying in the sand. "I saw that bottle and it looked interesting, " Korotkikh told The Associated Press on Tuesday."It looked like a German beer bottle and there was a message inside." It said, "My name is Frank, and I'm five years old.My dad and I are travelling on a ship to Denmark.If you find this letter, please write back to me, and I will write back to you." The letter, dated 1987, included an address in the town of Coesfeld. The boy in the letter, Frank Uesbeck, is now 29.His parents still live at the letter's address. The Russian boy and the German man met each other earlier this month through an Internet video link.The Russian boy said he did not believe that the bottle actually spent 24 years in the sea.He believed it had been hidden under the sand where he found it for a long time. Uesbeck was especially happy that he was able to have a positive effect on a life of a young person far away from Germany."It's really a wonderful story, " he said."And who knows? Perhaps one day we will actually be able to arrange a meeting in person."
Output: What is this passage mainly about?
Oxidatively damaged proteins accumulate with age in almost all cell types and tissues. The activity of chaperone-mediated autophagy (CMA), a selective pathway for the degradation of cytosolic proteins in lysosomes, decreases with age. We have analyzed the possible participation of CMA in the removal of oxidized proteins in rat liver and cultured mouse fibroblasts. Added to the fact that CMA substrates, when oxidized, are more efficiently internalized into lysosomes, we have found a constitutive activation of CMA during oxidative stress. Oxidation-induced activation of CMA correlates with higher levels of several components of the lysosomal translocation complex, but in particular of the lumenal chaperone, required for substrate uptake, and of the lysosomal membrane protein (lamp) type 2a, previously identified as a receptor for this pathway. In contrast with the well characterized mechanism of CMA activation during nutritional stress, which does not require de novo synthesis of the receptor, oxidation-induced activation of CMA is attained through transcriptional up-regulation of lamp2a. We conclude that CMA is activated during oxidative stress and that the higher activity of this pathway under these conditions, along with the higher susceptibility of the oxidized proteins to be taken up by lysosomes, both contribute to the efficient removal of oxidized proteins.
Output: Which is the receptor for substrates of Chaperone Mediated Autophagy?
The United States Exploring Expedition was an exploring and surveying expedition of the Pacific Ocean and surrounding lands conducted by the United States from 1838 to 1842.
Output: On what date did United States Exploring Expedition end?
When you take a walk along a beach, what do you find there? Sand, the ocean, lots of sunlight. You may also find shells. The shells you find are most likely left by organisms in the phylum Mollusca. On the beach, you can find the shells of many different mollusks ( Figure 1.1), including clams, mussels, scallops, oysters, and snails. Mollusks are invertebrates that usually have a hard shell, a mantle, and a radula. Their glossy pearls, mother of pearl, and abalone shells are like pieces of jewelry. Some mollusks, such as squid and octopus, do not have shells. The Mollusks body is often divided into different parts ( Figure 1.2): On the beach, you can find a wide variety of mollusk shells. 1. A head with eyes or tentacles. 2. In most species, a muscular foot, which helps the mollusk move. Some mollusks use the foot for burrowing into the sand, and others use it for jet-propulsion. 3. A mantle, or fold of the outer skin lining the shell. The mantle often releases calcium carbonate, which creates an external shell, just like the ones you find on the beach. The shell is made of chitin, a tough, semitransparent substance. 4. A mass housing the organs. 5. A complete digestive tract that begins at the mouth and runs to the anus. 6. Most ocean mollusks have a gill or gills to absorb oxygen from the water. 7. Many species have a feeding structure, the radula, found only in mollusks. The radula can be thought of as a "tongue-like" structure. The radula is made mostly of chitin. Types of radulae range from structures used to scrape algae off of rocks to the beaks of squid and octopuses. This is the basic body plan of a mollusk. Note the mantle, gills, and radula. Keep in mind the basic body plan can differ slightly among the mollusks. Mollusks are probably most closely related to organisms in the phylum Annelida, also known as segmented worms. This phylum includes the earthworm and leech. Scientists believe these two groups are related because, when they are in the early stage of development, they look very similar. Mollusks also share features of their organ systems with segmented worms. Unlike segmented worms, however, mollusks do not have body segmentation. The basic mollusk body shape is usually quite different as well.
Output: the mollusk shell is formed by the
The military aspect of the war began with the Armistice of Mudros. The military operations of the Greco-Turkish war can be roughly divided into three main phases: the first phase, spanning the period from May 1919 to October 1920, encompassed the Greek Landings in Asia Minor and their consolidation along the Aegean Coast. The second phase lasted from October 1920 to August 1921, and was characterised by Greek offensive operations. The third and final phase lasted until August 1922, when the strategic initiative was held by the Turkish Army.
Output: What was the shortest phase of the war?
As the largest recipient of investment per capita since 2000 in India, and among one of the wealthiest and most economically developed regions in South Asia, Haryana has the List of Indian states and union territories by GDP per capita per capita income among Indian states and union territories at against the national average of for year 201617. Haryanas 2017-18 estimated List of Indian states and union territories by GDP of US$95 billion (52% Service economy, 30% Industry and 18% Agriculture in India) is growing at 12.96% 2012-17 compound annual growth rate and placed on the list of Indian states and union territories by GDP behind only much bigger states, is also boosted by 30 special economic zones (mainly along DelhiMumbai Industrial Corridor Project, Amritsar Delhi Kolkata Industrial Corridor and Delhi Western Peripheral Expressway in National Capital Region (India)), 7% national agricultural exports, 60% of national Basmati rice export, 67% cars, 60% motorbikes, 50% tractors and 50% refrigerators produced in India. Faridabad has been described as eighth fastest growing city in the world and third most in India by City Mayors Foundation survey. In services, Gurugram ranks number 1 in India in IT growth rate and existing technology infrastructure, and number 2 in startup ecosystem, innovation and livability (Nov 2016).
Output: What rank does Faribad have for fastest growth in India?
Karl Weniger (24 May 1899 -- 1 October 1941) was a Kapitan zur See with the Kriegsmarine during World War II and a posthumous recipient of the Knight's Cross of the Iron Cross.
Output: In what war did Karl Weniger fight?
Restless legs syndrome (RLS), recently renamed Willis-Ekbom disease (WED), is a common movement disorder. It is characterised by the need to move mainly the legs due to uncomfortable, sometimes painful sensations in the legs, which have a diurnal variation and a release with movement. Management is complex. First, centres should establish the severity of RLS using a simple 10-item RLS severity rating scale (IRLS). They should also exclude secondary causes, in particular ensuring normal iron levels. Mild cases can be managed by lifestyle changes, but patients with a IRLS score above 15 usually require pharmacological treatment. Dopaminergic therapies remain the mainstay of medical therapies, with recent evidence suggesting opioids may be particularly effective. This article focuses on the different treatment strategies in RLS, their associated complications and ways to manage them.
Output: Willis-Ekbom disease is also known as?
Gaucher disease is an inborn recessive autosomal disease due to a partial deficiency of the lysosomal enzyme beta glucocerebrosidase. The deficient activity leads to accumulation of the lipid glucocerebroside in the liver, the spleen and bone marrow with concomitant anemia and thrombocytopenia. Patients with Gaucher disease have been classified in three types: type I is the more common, neurological manifestations occur in types II and III. Enzyme replacement therapy (ERT) with modified placental human glucocerebrosidase (ceredase) or recombinant glucocerebrosidase (cerezyme) is effective in most type I Gaucher disease and has become the current standard care administered to thousand of patients worldwide. ERT has obviated the need for bone marrow transplantation and virtually eliminated the need for splenectomy. We report here the French study including adults and children. ERT of 30 to 60 U/K every two weeks as starting dose was administrated to 108 patients with severe type I Gaucher disease. ERT fully reverse many of the manifestations of the disease. ERT regimen alleviated fatigue, and hematological and visceral signs and symptoms in nearly all severely-ill patients. Skeletal responses to treatment develop much more slowly than hematological or visceral responses. Studies in pediatrics show that the disease is more severe in children. These children should be treated early in the course of their disease to avoid irreparable damage. Hematological manifestation in type II cannot be reversed with enzyme replacement. In type III treatment can rarely reverse neurological deficit. Gaucher disease is also an excellent candidate for gene therapy.
Output: Which enzyme is deficient in Gaucher's disease?
Sailing Through History A group of 1,309 passengers boarded the MSBalmoralon Sunday, in Southampton, England, on a voyage to retrace the path of theTitanic. TheTitanicwas the biggest ship in the world when it sailed on its ill-fated maiden voyage in 1912. Of the 2,227 passengers and crew aboard, more than 1,500 died. The ship, which was headed to New York City, carried the rich and famous on its first voyage. It also carried immigrants, who were seeking a better life in America. Relatives of people who sailed on theTitanic, historians, authors and people fascinated by the story of the unsinkable ship, are on theBalmoral. They want to remember the doomed ship and those who died on her first and last voyage. The historic liner had set sail on April 10, 1912, from Southampton. Late at night on April 14, she hit an iceberg. In the early morning hours of April 15, theTitanicsank. TheBalmoralis followingTitanic's original route from Southampton. First, the modern-day cruise liner docked in the port of Cherbourg, France, where theTitanichad picked up more passengers. On Monday afternoon, theBalmoralstops in Cobh, Ireland, theTitanic's last port of call before sailing to New York. Balmoralwill then cruise the North Atlantic Ocean to the location whereTitanichit an iceberg that ripped the ship's hull . On Sunday, April 15, at 2:20 a.m.--the time theTitanicwent down--passengers and crew will hold a memorial service. The next two days will be spent in Halifax, Canada, where many victims of the sinking are buried. Then, theBalmoralwill reach its final destination in New York City, whereTitanicwas supposed to dock--but never did. Until today, several teams of divers have explored the site. They have recovered some items such as dishes and silverware and put them on public display. And more trips are planned to the wreckage in the future. TheTitanicand its passengers and crew have been remembered in books, movies and TV programs. But there's a much more important contribution thatTitanicgave us. After she sank, lawmakers and shipbuilders made ships safer. It took a terrible tragedy to make ship travel safer for all.
Output: How many countries does the Balmoral reach before sailing to New York?
Several properties of the atmosphere change with altitude, but the composition of the natural gases does not. The proportions of gases in the atmosphere are everywhere the same, with one exception. At about 20 km to 40 km above the surface, there is a greater concentration of ozone molecules than in other portions of the atmosphere. This is called the ozone layer. Nitrogen and oxygen together make up 99% of the planets atmosphere. Nitrogen makes up the bulk of the atmosphere, but is not involved in geological or biological processes in its gaseous form. Nitrogen fixing is described in the chapter Life on Earth. Oxygen is extremely important because it is needed by animals for respiration. The rest of the gases are minor components but sometimes are very important (Figure 1.1). Nitrogen and oxygen make up 99% of the atmosphere; carbon dioxide is a very important minor component. Humidity is the amount of water vapor in the air. Humidity varies from place to place and season to season. This fact is obvious if you compare a summer day in Atlanta, Georgia, where humidity is high, with a winter day in Phoenix, Arizona, where humidity is low. When the air is very humid, it feels heavy or sticky. Dry air usually feels more comfortable. When humidity is high, water vapor makes up only about 4% of the atmosphere. Where around the globe is mean atmospheric water vapor higher and where is it lower (Figure 1.2)? Why? Higher humidity is found around the equatorial regions because air temperatures are higher and warm air can hold more moisture than cooler air. Of course, humidity is lower near the polar regions because air temperature is lower. Remember that greenhouse gases trap heat in the atmosphere. Important natural greenhouse gases include carbon dioxide, methane, water vapor, and ozone. CFCs and some other man-made compounds are also greenhouse gases. Some of what is in the atmosphere is not gas. Particles of dust, soil, fecal matter, metals, salt, smoke, ash, and other solids make up a small percentage of the atmosphere and are called particulates. Particles provide starting points (or nuclei) for water vapor to condense on and form raindrops. Some particles are pollutants. Click image to the left or use the URL below. URL:
Output: humidity is how much of this is in the air.
Al-e Yusefi-ye Sofla (Persian: , also Romanized as Al-e Yusefi-ye Sofla; also known as Al-e Safi-ye Pa'in and Al-e Yusefi-ye Pa'in) is a village in Zirrah Rural District, Sadabad District, Dashtestan County, Bushehr Province, Iran.
Output: What is the name of Al-e Yusefi-ye Sofla's country?
SAN FRANCISCO--The "Reading Wizard", an 11 - year - old - boy, whose offer to read to children without being paid at a local library was refused by libraries, will get to read to younger kids after all. Mayor Willie Brown last Wednesday ordered San Francisco Public Library officials to allow John O'Connor to read to preschool children to get them interested in books and stop them from watching television and video games. "I didn't expect this kind of attention. " John said, "It's just shocking." John has chosen his first book, "The King's Giraffe", and made up fliers inviting neighborhood children, aged from three to six, to the Presidio Branch every Wednesday afternoon. He planned to call himself the "Reading Wizard" and wear a special hat, fake glasses and a black coat. But his idea was refused - on the phone, in person and finally with a letter from Toni Bernardi, the chief of the library's children and youth services. Using terms like "age appropriate material" ,she wrote that only library workers are allowed to read to children. John then went to a member of the city board of supervisors , who advised him to write letters to the library officials. "Our libraries are supposed to turn kids on, not to turn them off." Brown said he enjoyed "the creative idea, the sense of civic duty and the caring for others that John clearly showed us."
Output: Who is the "Reading Wizard"?
Cotinguiba Esporte Clube play their home games at Estadio Lourival Baptista, nicknamed Batistao.
Output: Which is the stadium of Cotinguiba Esporte Clube?
More than 500 unrelated patients with neurofibromatosis type 1 (NF1) were screened for mutations in the NF1 gene. For each patient, the whole coding sequence and all splice sites were studied for aberrations, either by the protein truncation test (PTT), temperature-gradient gel electrophoresis (TGGE) of genomic PCR products, or, most often, by direct genomic sequencing (DGS) of all individual exons. A total of 301 sequence variants, including 278 bona fide pathogenic mutations, were identified. As many as 216 or 183 of the genuine mutations, comprising 179 or 161 different ones, can be considered novel when compared to the recent findings of Upadhyaya and Cooper, or to the NNFF mutation database. Mutation-detection efficiencies of the various screening methods were similar: 47.1% for PTT, 53.7% for TGGE, and 54.9% for DGS. Some 224 mutations (80.2%) yielded directly or indirectly premature termination codons. These mutations showed even distribution over the whole gene from exon 1 to exon 47. Of all sequence variants determined in our study, <20% represent C-->T or G-->A transitions within a CpG dinucleotide, and only six different mutations also occur in NF1 pseudogenes, with five being typical C-->T transitions in a CpG. Thus, neither frequent deamination of 5-methylcytosines nor interchromosomal gene conversion may account for the high mutation rate of the NF1 gene. As opposed to the truncating mutations, the 28 (10.1%) missense or single-amino-acid-deletion mutations identified clustered in two distinct regions, the GAP-related domain (GRD) and an upstream gene segment comprising exons 11-17. The latter forms a so-called cysteine/serine-rich domain with three cysteine pairs suggestive of ATP binding, as well as three potential cAMP-dependent protein kinase (PKA) recognition sites obviously phosphorylated by PKA. Coincidence of mutated amino acids and those conserved between human and Drosophila strongly suggest significant functional relevance of this region, with major roles played by exons 12a and 15 and part of exon 16.
Output: Which is the gene mutated in type 1 neurofibromatosis?
For the first time in franchise history, the Cowboys wore white pants and navy jerseys. The jerseys are usually paired with silver pants. The white pants were the Color Rush pants with a navy/silver/navy stripe down the side, and the navy jersey is the regular alternate navy jersey, usually worn on Thanksgiving. The Cowboys outscored the Giants to win 30-17 and improve to 7-6 and 2-3 without Elliott. Despite the win against the Giants, the eventual Super Bowl champion Philadelphia Eagles clinched the NFC East title with the win against the Rams.
Output: Which team scored the most points?
Allelic polymorphism of the apolipoprotein E (ApoE) gene (ApoE 2, ApoE 3 and ApoE 4 alleles) gives rise to three protein isoforms (ApoE2, ApoE3 and ApoE4) that differ by 1 or 2 amino acids. Inheritance of the ApoE 4 allele is a risk factor for developing Alzheimer's disease (AD). The potential diagnostic value of ApoE protein levels in biological fluids (i.e. cerebrospinal fluid, plasma and serum) for distinguishing between AD patients and healthy elderly subjects is subject to great controversy. Although a recent study reported subnormal total ApoE and ApoE4 levels in the plasma of AD patients, other studies have found normal or even elevated protein levels (versus controls). Because all previously reported assays were based on immunoenzymatic techniques, we decided to develop an orthogonal assay based on targeted mass spectrometry by tracking (i) a proteotypic peptide common to all ApoE isoforms and (ii) a peptide that is specific for the 4 allele. After trypsin digestion, the ApoE4-specific peptide contains an oxidation-prone methionine residue. The endogenous methionine oxidation level was evaluated in a small cohort (n=68) of heterozygous 34 carriers containing both healthy controls and AD patients. As expected, the proportion of oxidized residues varied from 0 to 10%, with an average of 5%. We therefore developed a standardized strategy for the unbiased, absolute quantification of ApoE4, based on performic acid oxidization of methionine. Once the sample workflow had been thoroughly validated, it was applied to the concomitant quantification of total ApoE and ApoE4 isoform in a large case-control study (n=669). The final measurements were consistent with most previously reported ApoE concentration values and confirm the influence of the different alleles on the protein expression level. Our results illustrate (i) the reliability of selected reaction monitoring-based assays and (ii) the value of the oxidization step for unbiased monitoring of methionine-containing proteotypic peptides. Furthermore, a statistical analysis indicated that neither total ApoE and ApoE4 levels nor the ApoE/ApoE4 ratio correlated with the diagnosis of AD. These findings reinforce the conclusions of previous studies in which plasma ApoE levels had no obvious clinical significance.
Output: Which ApoE isoform is associated with atherosclerosis and Alzheimer's disease?
The Bank Job is a 2008 British crime film written by Dick Clement and Ian La Frenais, directed by Roger Donaldson, and starring Jason Statham, based on the 1971 Baker Street robbery in central London, from which the money and valuables stolen were never recovered.
Output: Which place does The Bank Job exist in?
Derrick Jensen is a prominent member of the Deep Green Resistance Advisory Board.
Output: Who started Deep Green Resistance?
Colonel Richard Hamilton Rawson, DL, JP (21 February 1863 - 11 October 1918) was a British Army officer and later a Conservative Party and National Party politician.
Output: What was the political party of Richard Hamilton Rawson?
In week 4, the Lions traveled across Lake Michigan to Green Bay, Wisconsin to play division rivals the Green Bay Packers. The Packers started the scoring in the first quarter with a 29-yard TD catch by Donald Driver from Aaron Rodgers. The Lions tied it up in the second quarter with a 23-yard TD catch by Calvin Johnson. The Packers took the lead with a 13-yard catch by Jermichael Finley. They added to their lead 17-yard catch by Greg Jennings. The Lions responded just before halftime with a 21-yard catch by Calvin Johnson. Just after the break, the Packers' Charles Woodson returned an interception for a touchdown. The Lions attempted a comeback with 4 consecutive field goals: from 39 yards and 52 yards in the 3rd quarter, and later from 49 yards and 24 yards in the 4th. With the loss, not only did the Lions fall to 0-4, but it also marked their 19th consecutive loss in Wisconsin.
Output: Who had the longest TD catch?
Not everyone had the same warning the people on Tillys beach had. The Boxing Day Tsunami of December 26, 2004 was by far the deadliest of all time (Figure 1.1). The tsunami was caused by the 2004 Indian Ocean Earthquake. With a magnitude of 9.2, it was the second largest earthquake ever recorded. The extreme movement of the crust displaced trillions of tons of water along the entire length of the rupture. Several tsunami waves were created with about 30 minutes between the peaks of each one. The waves that struck nearby Sumatra 15 minutes after the quake reached more than 10 meters (33 feet) in height. The size of the waves decreased with distance from the earthquake and were about 4 meters (13 feet) high in Somalia. The tsunami did so much damage because it traveled throughout the Indian Ocean. About 230,000 people died in eight countries. There were fatalities even as far away as South Africa, nearly 8,000 kilometers (5,000 miles) from the earthquake epicenter. More than 1.2 million people lost their homes and many more lost their ways of making a living. The countries that were most affected by the 2004 Boxing Day tsunami. The Japanese received a one-two punch in March 2011. The 2011 Tohoku earthquake offshore was a magnitude 9.0 and damage from the quake was extensive. People didnt have time to recover before massive tsunami waves hit the island nation. As seen in Figure 1.2, waves in some regions topped 9 meters (27 feet). The tsunami did much more damage than the massive earthquake (Figure 1.3). Worst was the damage done to nuclear power plants along the northeastern coast. Eleven reactors were automatically shut down. Power and backup power were lost at the Fukushima plant, leading to equipment failures, meltdowns, and the release of radioactive materials. Control and cleanup of the disabled plants will go on for many years. As a result of the 2004 tsunami, an Indian Ocean warning system was put into operation in June 2006. Prior to 2004, no one had thought a large tsunami was possible in the Indian Ocean. In comparison, a warning system has been in effect around the Pacific Ocean for more than 50 years. The system was used to warn of possible tsunami waves after the Tohoku earthquake, but most were too close to the quake to get to high ground in time. Further away, people were evacuated along many Pacific coastlines, but the waves were not that large.
Output: the magnitude of the earthquake that caused the boxing day tsunami of 2004 was
Coming off their home win over the Lions, the 49ers flew to the Louisiana Superdome for a Week 4 duel with the New Orleans Saints. In the first quarter, the Niners struck first as kicker Joe Nedney got a 47-yard field goal. In the second quarter, the Saints took the lead with QB Drew Brees completing a 5-yard and a 33-yard TD pass to WR Lance Moore. San Francisco would answer with Nedney's 49-yard field goal, yet New Orleans replied with Brees' 47-yard TD pass to WR Robert Meachem. In the third quarter, the 49ers tried to rally as Nedney kicked a 38-yard field goal. However, in the fourth quarter, the Saints continued to pull away as RB Deuce McAllister got a 1-yard TD run. The Niners tried to rally as QB J.T. O'Sullivan completed a 5-yard TD pass to WR Isaac Bruce, yet New Orleans sealed the win with kicker Martin Gramatica nailing a 31-yard field goal.
Output: Which player got the Saints on the board?
Mutations in the solute carrier family 9, subfamily A member 6 (SLC9A6) gene, encoding the endosomal Na+/H+ exchanger 6 (NHE6) are associated with Christianson syndrome, a syndromic form of X-linked intellectual disability characterized by microcephaly, severe global developmental delay, autistic behavior, early onset seizures and ataxia. In a 7-year-old boy with characteristic clinical and neuroimaging features of Christianson syndrome and epileptic encephalopathy with continuous spikes and waves during sleep, we identified a novel splice site mutation (IVS10-1G>A) in SLC9A6. These findings expand the clinical spectrum of the syndrome and indicate NHE6 dysfunction as a new cause of electrical status epilepticus during slow-wave sleep (ESES).
Output: Mutation of which gene is implicated in the Christianson syndrome?
Hip, Hip, Hurrah! (Danish: Hip, hip, hurra! Kunstnerfest pa Skagen) is an oil-on-canvas painting from 1888 by Norwegian-Danish painter Peder Severin Kryer.
Output: What is the surface of Hip, Hip, Hurrah! made of?
Hoping to snap a three-game losing streak, the Chiefs went home for a Week 12 Sunday night duel with the Pittsburgh Steelers. Kansas City delivered the game's first punch in the opening quarter with a 41-yard field goal from kicker Ryan Succop. The Steelers would answer in the second quarter with kicker Shaun Suisham getting a 21-yard field goal, followed by quarterback Ben Roethlisberger completing a 2-yard touchdown pass to tight end Weslye Saunders. The Chiefs would reply with a 49-yard field goal from Succop, but Pittsburgh would close out the half with Suisham booting a 49-yard field goal. After a scoreless third quarter, Kansas City began to chip away at their deficit in the fourth quarter with a 40-yard field goal from Succop. However, the Steelers' defense held on to preserve the win.
Output: Who kicked the second most field goals?
Meanwhile, in 1274, the former Dali Kingdom was officially reorganized as the Province of Yunnan, with Sayyid Ajjal Shams al-Din Omar as governor. In May 1275, the governor sent a report to the emperor stating that the embassy had not returned; that the Burmese evidently had no intention of submitting; and that war was the only way forward. But the emperor rejected an outright invasion. Just coming off a disastrous Japanese campaign, the emperor was unwilling to commit the central government troops to what he considered a low priority affair. He was now focused on delivering the final blow against the Song; the emperor ordered the Yunnan provincial army to secure the borderlands in order to block the escape path of the Song refugees. He also sanctioned a limited border war if Pagan contested the takeover. As planned, the Yunnan army proceeded to consolidate the borderlands in 1275-76. Elsewhere, the main Mongol armies had captured most of the Song territory by 1276. By 1277, at least one Burmese vassal state named "Gold Teeth" had submitted to the Mongols. Like in 1272, the Burmese government responded by sending an army to reclaim the rebellious state; but unlike in 1272, the Mongols had posted a sizable garrison there. Though it was ultimately under Mongol command, many of the officers and most of the soldiers of the garrison were Turkic-speaking peoples or people from the further west: Turks from Samarkand, Bukhara, Merv and Nishapur, but also captive soldiers from the Persian Khwarazmid empire, the Kipchaks, and even Bulgars from the lower Volga.
Output: Which happened first, the capture of Sond territory, or "Gold Teeth" submitting to the Mongols?
Sir Lionel is the younger son of King Bors of Gaunnes (or Gaul) and Evaine and brother of Bors the Younger in Arthurian legend.
Output: Who was the brother of Sir Lionel?
I'm not so sure I like my friends any more. I used to like them-to be honest. We'd have lunch, talk on the phone or exchange emails, and they all seemed normal enough. But then came Face Book, and I was introduced to a sad fact: many of my friends have dark sides that they had kept from me. Today my friends show off the more unpleasant aspects of their personalities via FaceBook. No longer hidden, they're thrown in my face like TV commercials -unavoidable and endless advertisements for the worst of their personalities. Take Fred. If you were to have lunch with him, you'd find him warm, and self-effacing .Read his FaceBook and you'll realize he's an unbearable, food-obsessed boring man. He'd pause to have a cup of coffee on his way to save a drowning man-and then write about it. Take Andy. You won't find a smarter CEO anywhere, but now he's a CEO without a company to run. So he plays Mafia Wars on FaceBook. He's doing well-level 731. Thanks to FaceBook, I know he's playing about 18 hours a day. Andy, you've run four companies-and this is how you spend your downtime? What happned to golf?What happened to getting another job? Take Liz. She is positive that the flu vaccine will kill us all and that we should avoid it. And then comes Chris who likes to post at least 20 times a day on every website he can find, so I get to read his thoughts twice, once on FaceBook and once on Twitter. In real life, I don't see these sides of people. Face to face, my friends show me their best. They're nice, smart people. But face to FaceBook, my friends is like a blind date which goes horribly wrong. I'm left with a dilemma. Who is my real friend?Is it the Liz I have lunch with or the anti-vaccine madman on FaceBook? Is it the Fred I can grab a sandwich with or the Fred who weeps if he's at a party and the wine isn't up to his standard?
Output: Who is opposed to the flu vaccine in the text?
Fotografiska is housed at Stadsgarden, in a former customs house in the Art Nouveau style dating from 1906.
Output: The art style of Fotografiska is what?
Prelude and Fugue in A minor, BWV 543 is a piece of organ music written by Johann Sebastian Bach sometime around his years as court organist to the Duke of Saxe-Weimar (1708--1717).
Output: What type of instrument is Prelude and Fugue in A minor, BWV 543 designed for?
The Sonoma Barracks (El Cuartel de Sonoma) is a two-story, wide-balconied, adobe building facing the central plaza of the City of Sonoma, California.
Output: Which is the kind of art style of Sonoma Barracks?
La Paz F.C. plays its home matches at Estadio Hernando Siles.
Output: Which is the stadium of La Paz F.C.?
Compelling evidence indicates that the CRISPR-Cas system protects prokaryotes from viruses and other potential genome invaders. This adaptive prokaryotic immune system arises from the clustered regularly interspaced short palindromic repeats (CRISPRs) found in prokaryotic genomes, which harbor short invader-derived sequences, and the CRISPR-associated (Cas) protein-coding genes. Here, we have identified a CRISPR-Cas effector complex that is comprised of small invader-targeting RNAs from the CRISPR loci (termed prokaryotic silencing (psi)RNAs) and the RAMP module (or Cmr) Cas proteins. The psiRNA-Cmr protein complexes cleave complementary target RNAs at a fixed distance from the 3' end of the integral psiRNAs. In Pyrococcus furiosus, psiRNAs occur in two size forms that share a common 5' sequence tag but have distinct 3' ends that direct cleavage of a given target RNA at two distinct sites. Our results indicate that prokaryotes possess a unique RNA silencing system that functions by homology-dependent cleavage of invader RNAs.
Output: Gene silencing can be achieved by RNA interference (RNAi) in eukaryotic organisms. What is the name of the analogous process in prokaryotic organisms?
Miguel Angel Garcia Tebar (born 26 September 1979), known as Miguel Garcia, is a Spanish retired footballer who played as a defensive midfielder.
Output: What role does Miguel Ángel García Tébar play in football?
Coming off their Monday night road win over the Saints, the Vikings went home for a Week 6 NFC North duel with the Detroit Lions. In the first quarter, the Vikes got an early lead as Lions QB Dan Orlovsky unintentionally ran out of the back of his own end zone, giving Minnesota a safety which Orlovsky didn't know why the whistles were blown. In the second quarter, Detroit got the lead as kicker Jason Hanson got a 40-yard field goal. In the third quarter, the Lions increased their lead as Orlovsky completed a 12-yard TD pass to WR Calvin Johnson. The Vikings answered with QB Gus Frerotte completing an 86-yard TD pass to WR Bernard Berrian. In the end of the fourth quarter, the Vikes got in field goal range due to a controversial pass interference call on Leigh Bodden. The Vikes sealed the win with kicker Ryan Longwell nailing the game-winning 26-yard field goal.
Output: Which QB threw the longest TD pass?
Australia has promised to introduce the most comprehensive carbon trading program outside Europe in 2010. The government in Canberra plans to cut greenhouse gas emissions by at least five percent by 2020, but it could make bigger reductions if other countries agree to tougher targets. The Australian government warns that without tough environmental measures the country could lose key industries and jobs. Climate Change Minister Penny Wong says the economy is under threat and decisive action is needed. Central to the government's climate change plan is a carbon emissions trading program that will be introduced within two years. It would involve one thousand of the nation's biggest companies and would cover about three-quarters of Australia's greenhouse gas emissions. Many scientists believe that greenhouse gases, such as carbon dioxide and methane, contribute to global warming. Many of them are released by burning fuels such as coal and oil. Companies will be required to buy permits for each ton of carbon they emit, although big polluting exporters will receive up to 90 percent of their carbon licenses free. Many business leaders want the government to delay the plan because of the current global financial crisis, which is slowing the Australian economy. Peter Anderson from the Australian Chamber of Commerce and Industry says it is irresponsible to bring in a carbon trading plan now. Environmentalists, on the other hand, say Prime Minister Kevin Rudd has not properly addressed the threat of climate change. Activists had sought a minimum emissions cut of 25 percent. Instead, the Rudd government aims to cuts carbon emissions by at least five percent of 2000 levels by 2020. That amount could rise to 15 percent, if future global agreements set such a target. Ray Nias of the environmental group WWF says Australia will pay the price for low targets. "This is a deeply, deeply disappointing target," Nias said. "It commits Australia to long-term climate change. It will make Australia's ability to negotiate global agreements very, very difficult. It is much lower than even we had imagined." Australia has one of the highest per-person greenhouse emissions rates in the world because of its reliance on coal for electricity. _
Output: Who most probably agrees to a higher goal of carbon emissions?
As of May, 2010, the California Secretary of State reports that San Benito County has 34,562 eligible voters. Of those 24,736 (71.57%) are registered voters. Of those, 11,959 (48.35%) are registered Democratic, 7,477 (30.23%) are registered Republican, 565 (2.28%)are registered American Independent, and 116 (0.47%) are Green Party. The two incorporated municipalities of Hollister and San Juan Bautista have Democratic majorities on their voter rolls, whereas the unincorporated areas of San Benito County have a small Republican plurality in voter registration.
Output: Are there more registered American Independent or Green Party voters?
The Thredbo River, a perennial river of the Snowy River catchment, is located in the Snowy Mountains region of New South Wales, Australia.
Output: Of what river is Thredbo River a tributary?
Billie Jenkins is a fictional character on The WB television series Charmed.
Output: In which fictional work is Billie Jenkins a character?
Redfield Proctor (June 1, 1831 -- March 4, 1908) was a U.S. politician of the Republican Party.
Output: From which political party is Redfield Proctor?
As of the census of 2000, there were 325,957 people, 149,937 households, and 94,460 families residing in the county. The population density was 570 people per square mile (220/km2). There were 182,467 housing units at an average density of 319 per square mile (123/km2). The racial makeup of the county was 92.65% Race (United States Census), 4.18% Race (United States Census) or Race (United States Census), 0.22% Race (United States Census), 0.77% Race (United States Census), 0.03% Race (United States Census), 1.14% from Race (United States Census), and 1.02% from two or more races. 4.34% of the population were Race (United States Census) or Race (United States Census) of any race. 89.7% spoke only English language at home; 4.4% spoke Spanish language, 1.3% German language, and 1.0% French language at home.
Output: Which group is smaller for the county according to the census: people or households?
Sheikha Al-Mayassa bint Hamad bin Khalifa Al-Thani (born 1983) is the sister of Qatar's ruling Emir Tamim bin Hamad Al Thani, and daughter of the country's Father Emir Hamad bin Khalifa Al Thani and former First Lady Moza bint Nasser.
Output: What is Al-Mayassa bint Hamad bin Khalifa Al-Thani's brothers name?
An earthquake is sudden ground movement caused by the sudden release of energy stored in rocks. Earthquakes happen when so much stress builds up in the rocks that the rocks rupture. The energy is transmitted by seismic waves. Earthquakes can be so small they go completely unnoticed, or so large that it can take years for a region to recover. The description of how earthquakes occur is called elastic rebound theory (Figure 1.1). Elastic rebound theory. Stresses build on both sides of a fault, causing the rocks to deform plastically (Time 2). When the stresses become too great, the rocks break and end up in a different location (Time 3). This releases the built up energy and creates an earthquake. Click image to the left or use the URL below. URL: In an earthquake, the initial point where the rocks rupture in the crust is called the focus. The epicenter is the point on the land surface that is directly above the focus (Figure 1.2). In the vertical cross section of crust, there are two features labeled - the focus and the epicenter, which is directly above the focus. Click image to the left or use the URL below. URL:
Output: the theory that stress builds up in rocks until they can no longer bend so they break, causing an earthquake is
SV Germania Schoneiche is a German association football club from Schoneiche in Brandenburg.
Output: To which sports is SV Germania Schöneiche related?
Clostridium difficile infection (CDI) is the main cause of nosocomial diarrhea in industrialized countries and the source of a growing number of cases of diarrhea in the community. The outbreak of the hypervirulent strain belonging to ribotype 027 has increased the incidence and severity of CDI in some countries. Although CDI usually courses as a mild diarrhea it can lead to severe forms such as toxic megacolon or septic shock. One of every 2 episodes of CDI is not diagnosed in Spanish hospitals due to a lack of clinical suspicion or the use of insensitive diagnostic methods. The diagnostic techniques of choice are algorithms based on the detection of glutamate dehydrogenase and molecular detection of the genes of the toxins with or without the direct detection of the toxins. The recommended treatment for CDI depends on the type of infection and the characteristics of the patient.
Output: Which main ribotype of Clostridium difficile is responsible of the recent outbreak?
Murat Ozcelik (born 1 January 1954) is a Turkish politician, civil servant and diplomat from the Republican People's Party (CHP), who has served as a Member of Parliament for Istanbul's third electoral district since 7 June 2015.
Output: What was the political party of Murat Özçelik?
In 1509, Diogo Lopes de Sequeira was sent to Malacca by the king of Portugal with four ships in order to establish contact with the Sultanate of Malacca. Initially, Sequeira was well received by the Sultan Mahmud Syah . Soon however, the Muslim community convinced Mahmud Syah that the Portuguese should be eliminated. Several men were captured and killed, but the ships escaped. Albuquerque first departed from India for Malacca in April 1511, with 1,200 men and 17 to 18 ships. Albuquerque's objective was to sever Islamic trade and Venetian trade on the same occasion.A first attack by the Portuguese failed on 25 July 1511. Albuquerque's captains spoke against another attempt, but he struck again, succeeding in capturing Malacca in August, despite strong resistance and the presence of artillery on the Malaccan side. In celebration, Tristao da Cunha was sent to Pope Leo X in Rome with rich presents including the elephant that the pope named Hanno.
Output: Which person traveled with more ships to Malacca, Diogo Lopes de Sequeira or Albuquerque?
The apolipoprotein E (APOE) 4 allele has been implicated in a range of neuropsychiatric conditions. The present research examined if the 4 allele of the APOE gene moderated the effect of combat exposure on posttraumatic stress disorder (PTSD) among Iraq/Afghanistan-era veterans. Participants included 765 non-Hispanic White (NHW) and 859 non-Hispanic Black (NHB) Iraq/Afghanistan-era veterans. A structured interview established psychiatric diagnoses. Combat exposure and PTSD symptom severity were assessed via self-report. The most common lifetime diagnoses were depression (39.2%), PTSD (38.4%), and alcohol dependence (24.38%). After correcting for multiple comparisons, no significant effects were observed on any of the outcomes among the NHW sample; however, within the NHB sample, significant gene environment (G E) interactions were observed for lifetime PTSD (P = .0029) and PTSD symptom severity (P = .0009). In each case, the APOE 4 allele had no effect on the outcomes when combat exposure was low; however, when combat exposure was high, an additive effect was observed such that 4 homozygotes exposed to high levels of combat reported the highest rates of PTSD (92%) and the worst symptom severity scores on the Davidson Trauma Scale (M = 79.5). Although preliminary, these findings suggest that the APOE 4 allele, in conjunction with exposure to high levels of combat exposure, may increase veterans' risk for developing PTSD.
Output: Symptoms of which disorder are evaluated with the Davidson Trauma Scale?
Willis-Ekbom disease/restless legs syndrome (WED/RLS) seems to be a frequent cause of intractable chronic insomnia (ICI) but is under-recognized in children/adolescents with neurodevelopmental conditions (NDCs), as many patients do not have the ability to express the underlying "urge-to-move". In light of this, we aim to develop a protocol for behavioral observations supporting the diagnosis of WED/RLS. We investigated 26 pediatric patients (age 1-16 years, median 8) with NDCs, ICI and evidence of familial WED/RLS employing (1) "emplotted narratives" for description of the various "urge-to-move" presentations and (2) self-description and "behavioral observations" during a "suggested clinical immobilization test" (SCIT). Parental narratives reflected typical WED/RLS-related "urge-to-move" symptoms during day-, bed-, and nighttime in all patients. Fifteen out of 26 patients could describe the "urge-to-move" during the SCIT. Ten out of 26 patients, unable to describe their symptoms due to cognitive disabilities, showed patterns of "relieving-movements" upon observation. Sensory processing abnormalities were reported in all patients, with tactile sensitivities (26/26) (including shifted pain threshold) as the most common sensory domain. "Emplotted narratives" and structured "behavioral observations" support recognition of familial WED/RLS associated movement patterns and provide a useful tool for the diagnosis of WED/RLS in children with NDCs in a clinical office setting.
Output: Willis-Ekbom disease is also known as?