niryuu/sni-each-converted huggingface dataset:
Playing in their second game of the season, the Cincinnati Bengals had a lot of things go wrong. Playing Ohio state rivals Cleveland Browns, the defense looked the exact opposite as they did in week one. Browns quarterback Derek Anderson started and threw for 328 yards and five touchdowns. It was only the third time in NFL history that two quarterbacks had thrown at least five touchdown passes in the same game. Jamal Lewis had 215 yards rushing with one touchdown and the Browns had two receivers with over 100 yards, Braylon Edwards and Kellen Winslow. The Bengals offense tried their best to keep the team in the game, however, as Carson Palmer threw for 6 TD's and Chad Johnson caught for 209 yards. The game started out slowly in the first quarter but the second quarter saw a combined 35 points scored. It was close in the end, when the Bengals started a drive with under one minute left. They managed to get the ball to the 50-yard line when Carson Palmer was intercepted by Leigh Bodden on an intended pass for Chad Johnson. This game ended up being the eighth highest scoring game in NFL history, but not the highest scoring game between these two teams. In 2004, the Bengals beat the Browns 58-48 for the second-most combined points. The Redskins (72) and Giants (41) combined for 113 points in 1966 for the most. Q1 - CIN - 10:40 - 13-yard TD pass from Carson Palmer to Rudi Johnson (Shayne Graham kick) (CIN 7-0) Q1 - CLE - 5:02 - Phil Dawson 39-yard FG (CIN 7-3) Q1 - CLE - 0:09 - Phil Dawson 39-yard FG (CIN 7-6) Q2 - CLE - 11:02 - 17-yard TD pass from Derek Anderson to Joe Jurevicius (Dawson kick) (CLE 13-7) Q2 - CIN - 7:40 - 23-yard TD pass from Carson Palmer to T. J. Houshmandzadeh (Graham kick) (CIN 14-13) Q2 - CLE - 6:37 - 9-yard TD pass from Derek Anderson to Joe Jurevicius (Dawson kick) (CLE 20-14) Q2 - CIN - 3:12 - 22-yard TD pass from Carson Palmer to Chad Johnson (Graham kick) (CIN 21-20) Q2 - CLE - 1:11 - 25-yard TD pass from Derek Anderson to Kellen Winslow (Dawson kick) (CLE 27-21) Q3 - CIN - 12:13 - Shayne Graham 20-yard FG (CLE 27-24) Q3 - CLE - 8:24 - 34-yard TD pass from Derek Anderson to Braylon Edwards (Dawson kick) (CLE 34-24) Q3 - CIN - 6:18 - 14-yard TD pass from Carson Palmer to Chad Johnson (Graham kick) (CLE 34-31) Q3 - CLE - 6:04 - Jamal Lewis 66-yard TD run (Dawson kick) (CLE 41-31) Q3 - CIN - 0:53 - 5-yard TD pass from Carson Palmer to T. J. Houshmandzadeh (Graham kick) (CLE 41-38) Q4 - CLE - 10:07 - 37-yard TD pass from Derek Anderson to Braylon Edwards (Dawson kick) (CLE 48-38) Q4 - CLE - 5:47 - Phil Dawson 18-yard FG (CLE 51-38) Q4 - CIN - 3:45 - 7-yard TD pass from Carson Palmer to Glenn Holt (Graham kick) (CLE 51-45)
Output: Which player completed the eleventh longest TD pass of the game?
The first step in the management of restless legs syndrome (RLS) is to identify, and if possible to treat any condition which might cause or worsen RLS, such as iron deficiency or some drug treatments. The patients suffering from RLS should be prompted to keep a healthy sleep schedule. Drug treatment should be restricted to patients with a clear clinical diagnosis, decided on an individual basis, when the clinical impact is serious. Four drug classes are central to the treatment of RLS: dopaminergic agents, some antiepileptics, opioids, and benzodiazepines. Dopaminergic agonists are the treatment of choice, especially when daily treatment is indicated, or if the symptoms are severe. Two dopaminergic agonists are licensed in France for the treatment of RLS: ropinirole (Adartrel) and pramipexole (Sifrol). After initiation of treatment, the patients should benefit from a regular follow-up in order to evaluate the efficacy of treatment and to identify possible side-effects. Special care should be given to the detection of augmentation, a phenomenon characterized by a paradoxical worsening of the symptoms with treatment. Some particular conditions, such as RLS comorbid with renal insufficiency, during pregnancy, and in the child are discussed.
Output: Which deficiency is the cause of restless leg syndrome?
Jeanne Deckers (17 October 1933 -- 29 March 1985), aka Jeannine Deckers, better known as Sur Sourire (''Sister Smile'', often credited as The Singing Nun in English-speaking countries), was a Belgian singer-songwriter and initially a member of the Dominican Order in Belgium as Sister Luc-Gabrielle.
Output: To which religious order did The Singing Nun belong?
The Niners broke the pattern of their first three games, and mounted a second half comeback to beat the Eagles (the 49ers trailed 21-10 in the second quarter). Philadelphia exploited Niner mistakes to score first half touchdowns on a blocked punt recovery, an interception return and a punt return. But the defense never allowed a point by the Eagles offense, who had led the league in scoring through the first 3 weeks of the season, and on the strength of two Colin Kaepernick touchdown passes and four Phil Dawson field goals, they took a late 26-21 lead. Late in the game the Eagles moved to the Niner one yard line, but they turned the ball over on downs, and the Niners held on for the win. The Niners outgained the Eagles 407-213, and held the ball for 42:17.
Output: Which team scored the least points all game?
Metabolic activation of the innate immune system governed by interleukin (IL)-1 contributes to -cell failure in type 2 diabetes. Gevokizumab is a novel, human-engineered monoclonal anti-IL-1 antibody. We evaluated the safety and biological activity of gevokizumab in patients with type 2 diabetes. In a placebo-controlled, dose-escalation study, a total of 98 patients were randomly assigned to placebo (17 subjects) or gevokizumab (81 subjects) at increasing doses and dosing schedules. The primary objective of the study was to evaluate the safety profile of gevokizumab in type 2 diabetes. The secondary objectives were to assess pharmacokinetics for different dose levels, routes of administration, and regimens and to assess biological activity. The study drug was well tolerated with no serious adverse events. There was one hypoglycemic event whereupon concomitant insulin treatment had to be reduced. Clearance of gevokizumab was consistent with that for a human IgG(2), with a half-life of 22 days. In the combined intermediate-dose group (single doses of 0.03 and 0.1 mg/kg), the mean placebo-corrected decrease in glycated hemoglobin was 0.11, 0.44, and 0.85% after 1, 2 (P = 0.017), and 3 (P = 0.049) months, respectively, along with enhanced C-peptide secretion, increased insulin sensitivity, and a reduction in C-reactive protein and spontaneous and inducible cytokines. This novel IL-1-neutralizing antibody improved glycemia, possibly via restored insulin production and action, and reduced inflammation in patients with type 2 diabetes. This therapeutic agent may be able to be used on a once-every-month or longer schedule.
Output: Which molecule is targeted by the drug Gevokizumab?
Coming off their come-from-behind win over the Dolphins, the Broncos traveled to Arrowhead Stadium for an AFC West rematch with the Kansas City Chiefs. The Broncos jumped out to a 14-0 lead on their first two possessions in the first quarter, with quarterback Peyton Manning throwing a pair of touchdown passes a 23-yarder to wide receiver Demaryius Thomas and a 15-yarder to running back C. J. Anderson. A 22-yard field goal by placekicker Connor Barth increased the Broncos' lead to 17-0 early in the second quarter. The scoring play occurred after the Broncos' special teams fooled the Chiefs with a fake punt run by safety David Bruton and a fourth-down conversion by Anderson. The Chiefs got on the scoreboard later in the second quarter, with quarterback Alex Smith connecting on a 20-yard touchdown pass to tight end Anthony Fasano. The Broncos' offense subsequently marched down the field, but had to settle on a 24-yard field goal by Barth just before halftime. The Chiefs' defense forced a fumble off Manning deep in Broncos' territory on the Broncos' first possession of the second half, but had to settle on a 39-yard field goal by placekicker Cairo Santos. Barth added two more field goals a 30-yarder midway through the third quarter and a 33-yarder early in the fourth quarter to increase the Broncos' lead to 26-10. The first field goal came after a DeMarcus Ware interception of Smith on a deflected pass, while the second field goal came after Chiefs' cornerback Marcus Cooper muffed a punt. The Chiefs narrowed the Broncos' lead, with Smith throwing a 12-yard touchdown pass to running back Jamaal Charles. However, Broncos' safety T. J. Ward knocked away a two-point conversion pass from Smith intended for Fasano that would have brought the Chiefs to within a one-score deficit. Barth added one more field goal a 37-yarder midway through the fourth quarter. The Broncos' defense subdued the Chiefs for the remainder of the game. With the win, the Broncos swept the Chiefs for a third consecutive season. Peyton Manning improved his personal record to 11-1 all-time in games against the Chiefs.
Output: Which kicker's initial field goal was longer?
Interleukin-6 (IL-6) can activate downstream signaling pathways in lung cancer cells, such as the STAT3 pathway, and is reported to be produced by tumor cells with activating EGFR mutations. We examined IL-6/STAT3 in lung cancer tumor tissues and the effects of siltuximab, a neutralizing antibody to human IL-6, in mouse models of lung cancer. IL-6 and STAT3 activation levels were compared with tumor histology and presence of KRAS mutations in snap-frozen, non-small-cell lung cancer tumors. The effects of siltuximab alone or in combination with erlotinib were examined in mouse xenograft models constructed using three cell line xenograft models and one primary explant mouse model. We examined the influence of cancer-associated fibroblasts (CAFs) on tumor growth and siltuximab effects. IL-6 levels were higher in tumors of squamous cell versus adenocarcinoma histology and were not associated with presence of KRAS mutations. Tyrosine phosphorylation status of STAT3 did not correlate with tumor IL-6 levels. Serine phosphorylation of STAT3 was correlated with KRAS mutation status. Both tumor and stromal cells contributed to total IL-6 within tumors. Siltuximab had minimal effect as a single agent in xenografts with tumor cells alone; however, in models coadministered with CAFs, siltuximab had more potent effects on tumor inhibition. We observed no effects of combined erlotinib and siltuximab. IL-6 is elevated in subsets of human NSCLCs, especially with squamous cell histology. Tumors supported by stromal production of IL-6 seem to be the most vulnerable to tumor growth inhibition by siltuximab.
Output: Which interleukin is blocked by Siltuximab?
As of the census of 2000, there were 218,590 people, 79,667 households, and 60,387 families residing in the county. The population density was 496 people per square mile (192/km). There were 83,146 housing units at an average density of 189 per square mile (73/km). The racial makeup of the county was 86.77% Race (United States Census), 9.27% Race (United States Census), 0.23% Race (United States Census), 1.52% Race (United States Census), 0.06% Race (United States Census), 0.69% from Race (United States Census), and 1.47% from two or more races. 1.91% of the population were Race (United States Census) or Race (United States Census) of any race. 22.5% were of German people, 13.1% Irish people, 9.8% Italian people, 9.2% English, 8.1% "American" and 6.0% Polish ancestry.
Output: Which ancestral group is smaller: German or Irish?
Hans Rottiger (16 April 1896 -- 15 April 1960) was a Panzer General in the German army during World War II and the first Inspector of the Army of the Bundeswehr.
Output: In which war did Hans Röttiger participate?
In the county, the population was spread out with 23.20% under the age of 18, 7.70% from 18 to 24, 27.00% from 25 to 44, 28.00% from 45 to 64, and 14.10% who were 65 years of age or older. The median age was 40 years. For every 100 females, there were 97.00 males. For every 100 females age 18 and over, there were 96.40 males.
Output: Which age group had the most people?
Apical membrane antigen 1 (AMA1) is an asexual blood-stage protein expressed in the invasive merozoite form of Plasmodia species, which are the causative agent of malaria. We have complemented the function of Plasmodium falciparum AMA1 (PfAMA1) with a divergent AMA1 transgene from Plasmodium chabaudi (PcAMA1). It was not possible to disrupt the PfAMA1 gene using 'knock-out' plasmids, although we demonstrate that the PfAMA1 gene can be targeted by homologous recombination. These experiments suggest that PfAMA1 is critical, perhaps essential, for blood-stage growth. Importantly, we showed that PcAMA1 expression in P. falciparum provides trans-species complementation to at least 35% of the function of endogenous PfAMA1 in human red cells. Furthermore, expression of this transgene in P. falciparum leads to more efficient invasion of murine erythrocytes. These results indicate an important role for AMA1 in the invasion of red blood cells (RBCs) across divergent Plasmodium species.
Output: Which is the causative agent of malaria?
Nearly everyone is shy in some ways. If shyness is making you uncomfortable, it may be time for a few lessons in self-confidence. You can build your confidence by following some suggestions from doctors and psychologists. Make a decision not to hold back in conversations. What you have to say is just as important as what other people say. And don't turn down party invitations just because of your shyness. Prepare for yourself for being with others in groups. Make a list of the good qualities you have. Then make a list of ideas, experiences, and skills you would like to share with other people . I think about what you would like to say in advance. Then say it. If you start feeling self-conscious in a group, take a deep breath and focus your attention on other people, Remember, you are not alone. Other people are concerned about the impression they are making, too. No one ever gets over being shy completely, but most people do learn to live with their shyness. Even entertainers admit that they often feel shy. They work at fighting their shy feelings so that they can face the cameras and the public. Just making the effort to control shyness can have many rewards. But perhaps the best reason to fight shyness is to give other people a chance to know about you.
Output: Who probably gives the suggestion for fighting shyness?
As of the 2010 United States Census, there were 1,951,269 people, 715,365 households, and 467,916 families residing in the county. The population density was . There were 840,343 housing units at an average density of . The racial makeup of the county was 60.9% white, 10.5% black or African American, 8.7% Asian, 0.7% Pacific islander, 0.7% American Indian, 13.5% from other races, and 5.1% from two or more races. Those of Hispanic or Latino origin made up 29.1% of the population. In terms of ancestry, 11.7% were Germans, 9.1% were Irish people, 7.6% were English people, 6.3% were Italians, and 2.7% were Americans.
Output: Were there more Whites or Asians?
According to 2011 census of India, Kumbakonam had a population of 140,156 with a sex-ratio of 1,021 females for every 1,000 males, much above the national average of 929. A total of 12,791 were under the age of six, constituting 6,495 males and 6,296 females.The average literacy of the city was 83.21%, compared to the national average of 72.99%. There were a total of 9,519 workers, comprising 32 cultivators, 83 main agricultural labourers, 1,206 in house hold industries, 7,169 other workers, 1,029 marginal workers, 24 marginal cultivators, 45 marginal agricultural labourers, 212 marginal workers in household industries and 0 other marginal workers.
Output: According to the census, which group is smaller: house hold industries or cultivators?
The Steelers' ninth game was an AFC duel with the Patriots. The Steelers trailed early as QB Tom Brady made a 19-yard TD pass to TE Rob Gronkowski. This was followed by kicker Shayne Graham getting a 31-yard field goal. The Steelers responded in the second quarter with kicker Jeff Reed nailing a 22-yard field goal. The Steelers struggled further when Brady threw another TD pass to Gronkowski, this one from 9yards out. That was followed by Brady's scramble 3yards to the endzone for a touchdown (With a failed PAT as the kick went wide-right). The Steelers scored first in the 4th quarter when QB Ben Roethlisberger completed a 6-yard TD pass to WR Emmanuel Sanders. The Steelers looked to create another scoring drive, but it came to a halt when Roethlisberger's pass was intercepted by SS James Sanders and returned 32yards for a touchdown (With a failed 2-point conversion). The Steelers tried to cut the lead with a Roethlisberger 15-yard TD pass to WR Mike Wallace, but the Patriots replied with Brady getting a 25-yard TD pass to Gronkowski. Again the Steelers tried to get closer when Roethlisberger completed a 33-yard TD pass to Wallace, but the Patriots put the game away after Graham hit a 36-yard field goal.
Output: Who caught the first TD pass?
The rebellion of the city of Danzig was a revolt from December 1575 to December 1577 of the city against the outcome of the Polish-Lithuanian royal election, 1576. The Polish throne was contested by Stephen Bathory and the Holy Roman Emperor Maximillian II. It began on 12 December 1575 when Emperor Maximillian was chosen as monarch by the Polish Senate, while the majority of the szlachta had voted for Bathory. It ended on 16 December 1577. Maximilian's II death in fall of 1576 weakened Danzig's position and made the conflict less about the recognition of the ruler than about Danzig's privileges. With neither side being able to defeat the other militarily, a compromise was reached, with economic as well as religious privileges of the city being restored and recognized, in return for a large reparation and recognition of Bathory as the king.
Output: Which person received the majority of the people's vote?
The European BioSafety Association (EBSA) is a non-profit organization, founded in June 1996, which provides a forum to its members to discuss and debate issues of concern and to represent those working in the field of biosafety and associated activities.
Output: When was European BioSafety Association established?
Sir Wilfred Robarts, a famed barrister, has just been released from the hospital in which he stayed for two months following a heart attack. Returning to his practise of law, he takes the case of Leonard Vole, an unemployed man who is accused of murdering his elderly friend, Mrs. Emily French. Vole claims he's innocent, although all evidence points to him as the killer, but his alibi witness, his cold German wife Christine, instead of entering the court as a witness for the defense, becomes the witness for the prosecution and defiantly testifies that her husband is guilty of the murder. Sir Wilfred believes there's something suspicious going on with the case, particularly with Mrs. Vole.
Output: Who is accused of murdering a rich widow?
Most of the time, you breathe without thinking about it. Breathing is mostly an involuntary action that is controlled by a part of your brain that also controls your heart beat. If you swim, do yoga, or sing, you know you can control your breathing, however. Taking air into the body through the nose and mouth is called inhalation. Pushing air out of the body through the nose or mouth is called exhalation. The woman pictured below is exhaling before she surfaces from the pool water (Figure 1.1). How do lungs allow air in? Air moves into and out of the lungs by the movement of muscles. The most important muscle in the process of breathing is the diaphragm, a sheet of muscle that spreads across the bottom of the rib cage. The diaphragm and rib muscles contract and relax to move air into and out of the lungs. During inhalation, the diaphragm contracts and moves downward. The rib muscles contract and cause the ribs to move outward. This causes the chest volume to increase. Because the chest volume is larger, the air pressure inside the lungs is lower than the air pressure outside. This difference in air pressures causes air to be sucked into the lungs. When the diaphragm and rib muscles relax, air is pushed out of the lungs. Exhalation is similar to letting the air out of a balloon. How does the inhaled oxygen get into the bloodstream? The exchange of gasses between the lungs and the blood happens in tiny sacs called alveoli. The walls of the alveoli are very thin and allow gases to pass though them. The alveoli are lined with capillaries (Figure 1.2). Oxygen moves from the alveoli to the blood in the capillaries that surround the alveoli. At the same time, carbon dioxide moves in the opposite direction, from capillary blood to the alveoli. The gases move by simple diffusion, passing from an area of high concentration to an area of low concentration. For example, initially there is more oxygen in the alveoli than in the blood, so oxygen moves by diffusion from the alveoli into the blood. The process of getting oxygen into the body and releasing carbon dioxide is called respiration. Sometimes breathing is called respiration, but there is much more to respiration than just breathing. Breathing is only the movement of oxygen into the body and carbon dioxide out of the body. The process of respiration also includes the exchange of oxygen and carbon dioxide between the blood and the cells of the body.
Output: the main muscle involved in breathing is the
This article explains what methicillin-resistant Staphylococcus aureus (MRSA) is, how it is spread and what the real challenges are in healthcare settings in the UK. It explores the different strains of MRSA and points out the main ways to control their spread. It is intended to be a reference source for all nurses.
Output: What is MRSA?
Hoping to rebound from a divisional home loss to the Eagles, the Cowboys flew to Bank of America Stadium for a Week 16 Saturday night duel with the Carolina Panthers. In the first quarter, Dallas shot first with QB Tony Romo completing a 10-yard TD pass to WR Terrell Owens for the only score of the period. In the second quarter, the 'Boys continued their assault as RB Marion Barber got a 5-yard TD run. The Panthers would get on the board with QB Matt Moore completing an 11-yard TD pass to WR Steve Smith. The Cowboys end the half with rookie kicker Nick Folk getting a 42-yard field goal. In the third quarter, Carolina started to try a comeback as kicker John Kasay getting a 37-yard field goal for the only score of the period. In the fourth quarter, Dallas would respond with Folk kicking a 23-yard field goal. The Panthers tried to rally as Kasay nailing a 25-yard field goal, yet the 'Boys were able to hold off every possible attempt. With the win, the Cowboys improved to 13-2 and clinched homefield through NFC Playoffs with Green Bay's loss to Chicago on Sunday. Terrell Owens (5 receptions for 48 yards and 1 touchdown) left the game in the second quarter with a high left ankle sprain.
Output: What team scored the first touchdown of the game?
Comets are small, icy objects that have very elliptical orbits around the Sun. Their orbits carry them from the outer solar system to the inner solar system, close to the Sun. Early in Earths history, comets may have brought water and other substances to Earth during collisions. Comet tails form the outer layers of ice melt and evaporate as the comet flies close to the Sun. The ice from the comet vaporizes and forms a glowing coma, which reflects light from the Sun. Radiation and particles streaming from the Sun push this gas and dust into a long tail that always points away from the Sun (Figure 1.1). Comets appear for only a short time when they are near the Sun, then seem to disappear again as they move back to the outer solar system. Comet Hale-Bopp, also called the Great Comet of 1997, shone brightly for several months in 1997. The comet has two visible tails: a bright, curved dust tail and a fainter, straight tail of ions (charged atoms) pointing directly away from the Sun. The time between one appearance of a comet and the next is called the comets period. Halleys comet, with a period of 75 years, will next be seen in 2061. The first mention of the comet in historical records may go back as much as two millennia. Short-period comets, with periods of about 200 years or less, come from a region beyond the orbit of Neptune called the Kuiper belt (pronounced KI-per). It contains not only comets, but also asteroids and at least two dwarf planets. Comets with periods as long as thousands or even millions of years come from a very distant region of the solar system called the Oort cloud, about 50,000 100,000 AU from the Sun (50,000 - 100,000 times the distance from the Sun to Earth). Click image to the left or use the URL below. URL:
Output: where do long-period comets come from?
The Battle of Maysalun (Arabic: ), also called the Battle of Maysalun Pass, was a battle fought between the forces of the Arab Kingdom of Syria and French Army of the Levant on 24 July 1920 near the Maysalun Pass, about 12 miles west of Damascus, close to the Lebanese border.
Output: On what date did Battle of Maysalun end?
Vedat Dalokay died in a traffic accident on March 21, 1991, in which his wife Ayca (age 44) and son Bars (age 17) were also killed.
Output: What cause of death was listed for Vedat Dalokay?
Sir Arthur Fell (7 August 1850 -- 29 December 1934) was an English solicitor and Conservative Party politician.
Output: What political party is Arthur Fell part of?
The Giants failed to capitalize on their win from the week before and once again were defeated by the Redskins for the season sweep. Washington never trailed in this game and forced Eli Manning into three interceptions. Although the Giants recorded two off of Rex Grossman, they never were able to get into any sort of offensive groove and lost 23-10. Washington led 17-3 at halftime and never looked back. Grossman threw for 185 yards and a touchdown to Santana Moss. Jabar Gaffney led the Redskins with 85 yards receiving while Hakeem Nicks recorded 73 for the Giants. Manning finished with 257 yards.
Output: Which team held a points lead all game?
In yeast, the macromolecular complex Set1/COMPASS is capable of methylating H3K4, a posttranslational modification associated with actively transcribed genes. There is only one Set1 in yeast; yet in mammalian cells there are multiple H3K4 methylases, including Set1A/B, forming human COMPASS complexes, and MLL1-4, forming human COMPASS-like complexes. We have shown that Wdr82, which associates with chromatin in a histone H2B ubiquitination-dependent manner, is a specific component of Set1 complexes but not that of MLL1-4 complexes. RNA interference-mediated knockdown of Wdr82 results in a reduction in the H3K4 trimethylation levels, although these cells still possess active MLL complexes. Comprehensive in vitro enzymatic studies with Set1 and MLL complexes demonstrated that the Set1 complex is a more robust H3K4 trimethylase in vitro than the MLL complexes. Given our in vivo and in vitro observations, it appears that the human Set1 complex plays a more widespread role in H3K4 trimethylation than do the MLL complexes in mammalian cells.
Output: Which is the histone residue methylated by MLL1?
Weathering is the process that changes solid rock into sediments. Sediments were described in the chapter "Ma- terials of Earths Crust." With weathering, rock is disintegrated. It breaks into pieces. Once these sediments are separated from the rocks, erosion is the process that moves the sediments. While plate tectonics forces work to build huge mountains and other landscapes, the forces of weathering gradually wear those rocks and landscapes away. Together with erosion, tall mountains turn into hills and even plains. The Appalachian Mountains along the east coast of North America were once as tall as the Himalayas. No human being can watch for millions of years as mountains are built, nor can anyone watch as those same mountains gradually are worn away. But imagine a new sidewalk or road. The new road is smooth and even. Over hundreds of years, it will completely disappear, but what happens over one year? What changes would you see? (Figure 1.1). What forces of weathering wear down that road, or rocks or mountains over time? A once smooth road surface has cracks and fractures, plus a large pothole. Click image to the left or use the URL below. URL:
Output: the process that changes solid rock into sediments.
Coming off their season-sweeping road win over the Bears, the Lions went home for a Week 9 interconference duel with the Denver Broncos. In the first quarter, Detroit attacked first with kicker Jason Hanson getting a 43-yard field goal for the first score of the game. In the second quarter, the Lions increased their lead with Hanson kicking a 53-yard field goal and QB Jon Kitna completing a 15-yard TD pass to WR Mike Furrey. Detroit ended the half with Hanson kicking a 38-yard field goal. In the third quarter, the Lions continued their domination as DE Dewayne White returned a fumble 3 yards for a touchdown and Kitna completed a 49-yard TD pass to WR Shaun McDonald. In the fourth quarter, Detroit sealed Denver's doom with NT Shaun Rogers returning an interception 66 yards for a touchdown and RB T. J. Duckett scoring on a 3-yard TD run. The Broncos avoided getting shut out as QB Patrick Ramsey completed a 2-yard TD pass to WR Brandon Stokley. With the win, the Lions improved to 6-2 for the first time since 1999.
Output: Which players scored field goals?
After winning in a close game at home, the Steelers traveled to Cincinnati for Game 2 against the Bengals. The Bengals scored first in the first quarter when Randy Bullock kicked a 35-yard field goal to make it 3-0. They would then make it 10-0 when Andy Dalton found A.J. Green on an 8-yard pass. In the second quarter, Dalton and Green connected again on a 15-yard pass to make it 17-0. The Steelers managed to get on the board before halftime when Chris Boswell put a 30-yard field goal through to make the score 17-3. In the third quarter, the Steelers drew closer when Ben Roethlisberger found Le'Veon Bell on a 35-yard touchdown to make it 17-10. The Bengals moved back ahead by double digits when Randy Bullock kicked a 31-yard field goal to make it 20-10. In the fourth quarter, it was all Steelers when Boswell put up a 37-yard field goal to make it 20-13. Roethlisberger then found Antonio Brown on a 6-yard pass to tie the game up at 20-20. Finally, Boswell was able to seal the victory with a 38-yard field goal to make the final score 23-20. With their sixth straight win over the Bengals, the Steelers improved to 10-2. The victory marks the third time that the Steelers have recorded two different 7+ win streaks within consecutive and separate regular seasons (1975-76, 1994-95). The team also won their 8th straight game against a divisional opponent. With the win, the Steelers began 4-0 in their division for the first time since 2008. The 17-point comeback was the Steelers' largest since they came back from down 17 on December 20, 2015 against the Denver Broncos, and their largest on the road since their 21-point comeback on October 5, 1997 against the Baltimore Ravens.
Output: Which player kicked the second-longest field goal?
Mie Kumagai is a Sega video game producer since 1993, and when the previous boss of the Hitmaker development studio Hisao Oguchi was promoted to president of the whole company, Kumagai became the new studio head and the first ever female president within Sega's development structure.
Output: What is Mie Kumagai's place of employment?
If the outside environment of a cell is water-based, and the inside of the cell is also mostly water, something has to make sure the cell stays intact in this environment. What would happen if a cell dissolved in water, like sugar does? Obviously, the cell could not survive in such an environment. So something must protect the cell and allow it to survive in its water-based environment. All cells have a barrier around them that separates them from the environment and from other cells. This barrier is called the plasma membrane, or cell membrane. The plasma membrane ( Figure 1.1) is made of a double layer of special lipids, known as phospholipids. The phospholipid is a lipid molecule with a hydrophilic ("water-loving") head and two hydrophobic ("water-hating") tails. Because of the hydrophilic and hydrophobic nature of the phospholipid, the molecule must be arranged in a specific pattern as only certain parts of the molecule can physically be in contact with water. Remember that there is water outside the cell, and the cytoplasm inside the cell is mostly water as well. So the phospholipids are arranged in a double layer (a bilayer) to keep the cell separate from its environment. Lipids do not mix with water (recall that oil is a lipid), so the phospholipid bilayer of the cell membrane acts as a barrier, keeping water out of the cell, and keeping the cytoplasm inside the cell. The cell membrane allows the cell to stay structurally intact in its water-based environment. The function of the plasma membrane is to control what goes in and out of the cell. Some molecules can go through the cell membrane to enter and leave the cell, but some cannot. The cell is therefore not completely permeable. "Permeable" means that anything can cross a barrier. An open door is completely permeable to anything that wants to enter or exit through the door. The plasma membrane is semipermeable, meaning that some things can enter the cell, and some things cannot. The inside of all cells also contain a jelly-like substance called cytosol. Cytosol is composed of water and other molecules, including enzymes, which are proteins that speed up the cells chemical reactions. Everything in the cell sits in the cytosol, like fruit in a jello mold. The term cytoplasm refers to the cytosol and all of the organelles, the specialized compartments of the cell. The cytoplasm does not include the nucleus. As a prokaryotic cell does not have a nucleus, the DNA is in the cytoplasm.
Output: the plasma membrane is made of a double layer of __________.
Every day when I enter the classroom, I will take a look at the wall beside my seat. You will find nothing special about this old wall if you just look at it. But for the students in my class, it is a special wall. Take a good look at it, and you will get to know the real feelings and thoughts of us, the 9th graders. In the middle of the wall, there is a big "VICTORY". It was written in pencil. I guess it must have been written by someone who got a good mark in an exam. A little higher above the formulas, there is a poem. It only has two sentences. It reads: All those sweet memories have disappeared. Like tears dropping in the heavy rain. Oh! It must have been written at the end of the last semester in middle school. Classmates had to leave school and good friends had to _ . What a sad poem! If you "explore" the wall more carefully, you will find many other interesting things, like a crying face, or a happy face, and other patterns . There are still some patterns and letters that I can't understand, but they all show the feeling of the students who drew them. For years, the wall has witnessed all the things that have happened in the classroom. I don't know how it will be next year, two years from now, or even ten years from now. But I hope more smiling faces will be drawn on it.
Output: When has the poem been written?
At 60, rue des Archives, this Hotel de Guenegaud was built between 1651 and 1655 for Jean-Francois de Guenegaud des Brosses, secretaire du Roi, maitre des Comptes and conseiller d'Etat, by Francois Mansart (the only hotel particulier this architect built to have fully survived).
Output: Who was behind the creation of Hôtel de Guénégaud?
Last week I visited my friend Pete in the new home where he lives with his wife and daughter. Pete used to spend his holidays travelling the world, visiting the pyramids in Egypt or scuba diving in the Caribbean. Nowadays he prefers to spend his holidays and weekends making his house look more beautiful. Like hundreds of thousands of other British people, he has discovered the joy of DIY (Do It Yourself), which means if there are any things that need fixing around the house, he will try to do the job himself. As he showed me the new kitchen he put together by himself and the newly painted walls, I asked Pete where he got his inspiration from. He told me that his favorite source of ideas was a DIY program on TV. This got me thinking about the great popularity of DIY programs in the UK. Each major channel has at least one home or garden improving show and there's even a satellite channel completely about the subject. I guess it is not really surprising that DIY programs are so popular. Two common sayings in Britain- 'an Englishman's home is his castle' and 'there's no place like home'-show how important our houses are to us. With the present economic downturn, many people can't afford to buy a bigger house so they are looking at how they can make their house better without spending a lot of money. DIY is the perfect choice. But be careful! I read a report that said over 230,000 people were injured while doing home improvements in the UK in just one year, including 41,000 who fell off ladders and 5,800 who were seriously hurt by hammers. So I won't be going down to the hardware store.
Output: Which might NOT be shown in a DIY program on TV?
Mathematical Models and Methods in Applied Sciences is a journal founded in 1991 and published by World Scientific.
Output: What business published Mathematical Models and Methods in Applied Sciences?
Sleep disorders are frequent comorbidities in neurologic patients. This review focuses on clinical aspects and prognosis of 3 neurologic sleep disorders: narcolepsy, restless legs syndrome/Willis-Ekbom disease (RLS/WED), and REM sleep behavior disorder (RBD). Narcolepsy causes pervasive, enduring excessive daytime sleepiness, adversely affecting patients' daily functioning. RLS/WED is characterized by an uncomfortable urge to move the legs before sleep, often evolving toward augmentation and resulting in daylong bothersome symptoms. RBD causes potentially injurious dream enactment behaviors that often signify future evolution of overt synucleinopathy neurodegeneration in as many as 81% of patients. Timely recognition, referral for polysomnography, and longitudinal follow-up of narcolepsy, RLS/WED, and RBD patients are imperatives for neurologists in providing quality comprehensive patient care.
Output: Willis-Ekbom disease is also known as?
Making Plans for Lena (French: Non ma fille, tu n'iras pas danser) is a 2009 French film directed by Christophe Honore, who co-wrote the screenplay with Genevieve Brisac.
Output: Who directed Making Plans for Lena?
During the major economic depression of the early 1890s, the Pullman Palace Car Company cut wages in its factories. Discontented workers joined the American Railway Union , led by Eugene V. Debs, which supported their strike by launching a boycott of all Pullman cars on all railroads. ARU members across the nation refused to switch Pullman cars onto trains. When these switchmen were disciplined, the entire ARU struck the railroads on June 26, 1894. Within four days, 125,000 workers on twenty-nine railroads had people quit work rather than handle Pullman cars. Strikers and their supporters also engaged in riots and sabotage. The railroads were able to get Edwin Walker, general counsel for the Chicago, Milwaukee, and St. Paul Railway, appointed as a special federal attorney with responsibility for dealing with the strike. Walker went to federal court and obtained an injunction barring union leaders from supporting the boycott in any way. The court injunction was based on the Sherman Anti-Trust Act which prohibited "Every contract, combination in the form of trust or otherwise, or conspiracy, in restraint of trade or commerce among the several States". Debs and other leaders of the ARU ignored the injunction, and federal troops were called into action. The strike was broken up by United States Marshals and some 2,000 United States Army troops, commanded by Nelson Miles, sent in by President Grover Cleveland on the premise that the strike interfered with the delivery of U.S. Mail. During the course of the strike, 13 strikers were killed and 57 were wounded. An estimated $340,000 worth of property damage occurred during the strike. Debs went to prison for six months for violating the federal court order, and the ARU disintegrated.
Output: What happened first: Pullman Palace Car company cut wages or strike was broken up?
The Chargers' fourteenth game was an interconference duel with the 49ers which was played on Thursday Night. The Chargers took a quick lead with QB Philip Rivers throwing a 58-yard TD pass to WR Vincent Jackson. The lead was extended in the second quarter by kicker Nate Kaeding nailing a 25-yard field goal, followed by Rivers finding Jackson on an 11-yard touchdown pass. The Chargers continued to dominate with FB Mike Tolbert getting a 1-yard TD run, followed by Rivers connecting to Jackson on a 48-yard TD pass, then with Kaeding hitting a 39-yard field goal. The 49ers made their only score of the game with RB Brian Westbrook getting a 1-yard TD run. This game was also a blowout and San Diego improved to 8-6.
Output: How many yards was the shortest touchdown run?
Captain Jack Harkness is a fictional character played by John Barrowman in Doctor Who and its spin-off series, Torchwood.
Output: What work of fiction is Jack Harkness located in?
Fred Fish died at his home in Idaho on Friday April 20, 2007 of a heart attack.
Output: From what did Fred Fish die?
Inflammation plays an important role in the pathophysiology of atherosclerosis and endothelial dysfunction, and occurs after percutaneous coronary intervention (PCI). We evaluated whether endothelial function is attenuated after PCI and if inhibition of secretory phospholipase A2 (sPLA2) activity augments endothelial function and coronary flow reserve (CFR) in these patients. In the sPLA2 Inhibition to Decrease Enzyme Release After Percutaneous Coronary Intervention (SPIDER-PCI) study, patients undergoing elective PCI were randomized to receive Varespladib (Anthera Pharmaceuticals Inc, San Mateo, CA), an inhibitor of sPLA2, or placebo 3-5 days prior to PCI and for 5 days after PCI. In this substudy, endothelial function was assessed in 31 patients by flow-mediated dilation (FMD) before treatment and on the day after PCI, while taking study medication. During the PCI procedure, CFR was assessed using a Doppler guide wire. Baseline and procedural characteristics were comparable in both groups and sPLA2 activity was similar at baseline. After PCI, sPLA2 activity decreased only in the Varespladib group (2.9 0.9 to 0.5 0.4 ng/mL), and high-sensitivity C-reactive protein (hsCRP) increased by more than 100% in both groups. FMD at baseline was 3.66 2.45% (Varespladib) and 3.37 1.73% (placebo) with nonsignificant increase in both groups after PCI. The effect of Varespladib on FMD, adjusted for pre-PCI FMD by linear regression, was -1.16 1.68%; P = 0.5. CFR was 2.45 0.66 and 2.77 0.85 in the Varespladib and placebo groups, respectively (P = 0.36). Systemic endothelial function is not reduced after elective PCI despite eliciting acute inflammatory response. Acute inhibition of sPLA2 activity with Varespladib does not affect endothelial or microvascular function after PCI.
Output: Which enzyme is inhibited by Varespladib?
A new study suggests that listening to music in the office improves the speed and accuracy of tasks such as data entry, proof reading and problem solving. In an office-based experiment, 88 per cent of participants were found to produce their most accurate work when listening to music. The study also found that 81 per cent completed their fastest work when music was played. And it matters what type of music you listen to. For instance, if you're doing your tax returns, then classical music is the most effective as it improves maths skills. Listening to Jessie Jor Justin Bieber could also improve your speed, with 58 per cent of participants completing data entry tasks faster while listening to pop songs. During proof-reading, dance music, such as David Guetta, had the biggest positive impact with participants increasing their speed by 20 per cent compared to tests undertaken with no music at all. Dance music also had a positive effect on spell-checking with a 75 per cent pass rate compared to 68 per cent when no music was played at all. The research, undertaken by Brighton-based Mind lab International, suggests that silent offices may be the least productive. 'The Music Works experiment revealed a positive _ between music and productivity - overall it showed that when listening to music, nine out of 10 people performed better,' said Dr David Lewis, chairman of Mind lab International.
Output: Supposing you are an office worker doing tax returns, what kind of music can improve your working efficiency?
Richard Packard is an American physicist, a professor at the University of California, Berkeley, known for having built the first quantum gyroscope with his colleagues.
Output: What is Richard Packard's place of employment?
NeXTSTEP (also stylized as NeXTstep, NeXTStep, and NEXTSTEP) is a combination of several parts: a Unix operating system based on the Mach kernel, plus source code from BSD Display PostScript and a proprietary windowing engine the Objective-C language and runtime an object-oriented (OO) application layer, including several ''kits'' development tools for the OO layers NeXTSTEP is notable for having been a preeminent implementation of the latter three items.
Output: What is the programming language for NeXTSTEP?
Paul Stanton (Mulroney) and his wife Diane (Diane Kruger) are a couple whose daughter is dying from a rare degenerative lung condition. The only thing that can save her life is a lung transplant from an organ donor. The movie starts when the donated lung fails to arrive correctly. The movie goes back and forth between the present and the events leading up to it. In the present day, Paul goes to Juarez, Mexico to find a man called Dr. Navarro. After leaving his cell number at many local hospitals, somebody finally contacts Paul. In the past, Dr. Rubin (Arquette), who's treating their daughter (Stallard), had given them information regarding Paul's associate, Harrison (Shepard), who somehow managed to get an organ transplant for himself, possibly from the black market. Paul confronted Harrison and finally managed to get Dr. Navarro's name from him. Harrison told him that he was contacted by Navarro and he didn't know how to reach him. Back in the present day, Paul is ambushed by a couple of Navarro's guys that tell him to stay away. After an arduous search, Paul finally finds out that Dr. Navarro is actually Dr. Martinez (Perez) from a local hospital that he visited previously for his wounds. Paul confronts Martinez and asks him to find a lung donor for his daughter, who only has one week to live. Martinez agrees to help him for a $250,000 cash payment. The next day, Martinez tells Paul that he has found a matching donor for his daughter. Paul tells Diane to go to Juarez and prepare their daughter for the transplant operation. Little does Paul know that the donor is actually a live person; Martinez and his men have planned a hit-and-run accident to get the lung implant from a local street boy. Paul discovers this fact and tells Diane about it. Diane tells him that she does not want to know where the donor comes from. Paul confronts Martinez at the operating table. Martinez tells Paul to make a choice: to go ahead with the operation or disband the operation knowing that they won't be able to find another match in time to save his daughter's life. The next scene shows Paul and Diane at their daughter's funeral. Diane gives Paul an accusing look blaming him for their daughter's death. Meanwhile, elsewhere, the local boy that was supposed to be the organ donor is alive and playing soccer with his friends.
Output: Where does Dr. Navarro perform transplants?
Apolipoprotein A-IV (also known as apoA-IV, apoAIV, or apoA4) is plasma protein that is the product of the human gene APOA4.
Output: Which species has the APOA4 gene?