niryuu/sni-each-converted huggingface dataset:
Context: There are many things you can do to protect yourself before, during, and after an earthquake. Have an engineer evaluate the house for structural integrity. Make sure the separate pieces floor, walls, roof, and foundation are all well-attached to each other. Bracket or brace brick chimneys to the roof. Be sure that heavy objects are not stored in high places. Secure water heaters all around and at the top and bottom. Bolt heavy furniture onto walls with bolts, screws, or strap hinges. Replace halogen and incandescent light bulbs with fluorescent bulbs to lessen fire risk. Check to see that gas lines are made of flexible material so that they do not rupture. Any equipment that uses gas should be well secured. Everyone in the household should know how to shut off the gas line. Prepare an earthquake kit with three days supply of water and food, a radio, and batteries. Place flashlights all over the house and in the glove box of your car. Keep several fire extinguishers around the house to fight small fires. Be sure to have a first aid kit. Everyone should know basic first aid and CPR. Plan in advance how you will evacuate and where you will go. Do not plan on driving, as roadways will likely be damaged. If you are in a building, get beneath a sturdy table, cover your head, and hold on. Stay away from windows, mirrors, and large furniture. If the building is structurally unsound, get outside as fast as possible. If you are outside, run to an open area away from buildings and power lines that may fall. If you are in a car, stay in the car and stay away from structures that might collapse, such as overpasses, bridges, or buildings. Be aware that aftershocks are likely. Avoid dangerous areas like hillsides that may experience a landslide. Turn off water and power to your home. Use your phone only if there is an emergency. Many people will be trying to get through to emergency services. Be prepared to wait for help or instructions. Assist others as necessary. Click image to the left or use the URL below. URL: 
 Question: which of these needs to be done after an earthquake?
Output: turn off water and power to your home.
Context: Vanoxerine has been in clinical trials for Parkinsonism, depression and cocaine addiction but lacked efficacy. Although a potent blocker of hERG, it produced no serious adverse events. We attributed the unexpected result to offsetting Multiple Ion Channel Effects (MICE). Vanoxerine's effects were strongly frequency-dependent and we repositioned it for treatment of atrial fibrillation and flutter. Vanoxerine terminated AF/AFL in an animal model and a dose-ranging clinical trial. Reversion to normal rhythm was associated with QT prolongation yet absent proarrhythmia markers for Torsade de Pointes (TdP). To understand the QT/TdP discordance, we used quantitative profiling and compared vanoxerine with dofetilide, a selective hERG-blocking torsadogen used for intractable AF, verapamil, a non-torsadogenic MICE comparator and bepridil, a torsadogenic MICE comparator. At clinically relevant concentrations, verapamil blocked hCav1.2 and hERG, as did vanoxerine and bepridil both of which also blocked hNav1.5. In acute experiments and simulations, dofetilide produced early after depolarizations (EADs) and arrhythmias, whereas verapamil, vanoxerine and bepridil produced no proarrhythmia markers. Of the MICE drugs only bepridil inhibited hERG trafficking following overnight exposure. The results are consistent with the emphasis on MICE of the CiPA assay. Additionally we propose that trafficking inhibition of hERG be added to CiPA. 
 Question: What alternate indication has Vanoxerine been repositioned for?
Output: atrial fibrillation and flutter
Context: After an inquest held in a nearby hotel, Florence Maybrick was charged with his murder and stood trial at St George's Hall, Liverpool, before Justice James Fitzjames Stephen, where she was convicted and sentenced to death. 
 Question: Which crime Florence Maybrick is considered to have commited?
Output: murder
Context: The U.S. Census for 2010 reported 332,199 households in Indianapolis, with an average household size of 2.42 and an average family size of 3.08. Of the total households, 59.3% were family households, with 28.2% of these including the familys own children under the age of 18; 36.5% were husband-wife families; 17.2% had a female householder (with no husband present) and 5.6% had a male householder (with no wife present). The remaining 40.7% were non-family households. , 32% of the non-family households included individuals living alone, 8.3% of these households included individuals age 65 years of age or older. 
 Question: Which group from the census is smaller: family households or husband-wife families?
Output: husband-wife families
Context: Bernard de Castanet (c. 1240 -- 14 August 1317) was the bishop and cardinal of the Roman Catholic Church. 
 Question: Which was the position that Bernard de Castanet held?
Output: bishop
Context: In 1996, Milo ukanovic's government severed ties between Montenegro and the Serbian regime, which was then under Slobodan Milosevic. 
 Question: Which person was the head of government of Montenegro?
Output: milo đukanović
Context: At Peikapw, a place of prayer, Isokelekel saw his reflection in a pool of water and, realizing his old age, decided to commit suicide. 
 Question: Was the death of Isokelekel an accident or suicide?
Output: suicide
Context: The MIT Museum is located near the north shore of the Charles River Basin in Cambridge, MA, a few blocks from the central part of the MIT campus. The MIT Museum is accessible via public transportation, and is within three miles of two major interstate highways. The Museum is approximately a 30 minute walk from downtown Boston or from Harvard Square. BY SUBWAY Take the Red Line to either Central Square Station or Kendall Square/MIT Station. From Central Square: Walk down Mass. Ave. toward Boston and the main MIT campus. The Museum is on the left at the corner of Front St. From Kendall/MIT Station at the east end of campus: Walk down Main St., away from Boston, to Windsor St., turn left, take the second right onto Front St., and continue to the museum entrance. BY BUS The Dudley/Harvard Square bus travels along Massachusetts Ave. between Boston and Harvard Square. The MIT Museum is across the street from Novartis and a gas station. From Harvard Square, get off at either Sidney St. or Albany St. From Boston, get off at Front St. BY CAR For directions from your doorstep to MIT, Google offers excellent mapping services including directions from anywhere in the U.S. and Canada. Recorded Directions to the Museum: (415) 561-0399 Besides, you can go the Museum via Commuter Rail. You can easily connect to the MBTA Red Line from South Station, or take the green line to the red line from North Station and get off at Central or Kendall Square. 
 Question: What should you do if you want to get Recorded Directions to the Museum?
Output: (415) 561-0399
Context: An interesting study posted on Facebook recently shows how men and women develop new interests as they mature . While women tend to take exercise seriously from the age of 34, men will wait until their 45th birthdays before working hard to get in shape. The average woman spends more time talking about sports, politics, career and money as she gets older. Women's interest in books reaches its peak at the age of 22, while that of men does so when they are in their 50s. Men start to change their focus from the workplace to other things after age 30, while women do not do so until eight years later. Both, however, care most about fashion at age 16. The research used anonymous data donated by thousands of Facebook users, recording the statuses, 'likes' and 'interests' they had posted on their profiles. It found the average woman talks about television most at 44, while men peak much younger, at age 31. Men are also most likely to see a film in a cinema at age 31, while women go out to see films most when they are only 19. Men are most interested in travel at 29, women at 27, while women talk most about food and drink at 35, and men at 38. And if you are middle aged, a safe topic for any audience is the weather, which is a key interest for many as they approach 60. Stephen Wolfram, the British scientist who carried out the research, says, "It's almost shocking how much this tells us about the changes of people's typical interests. "People talk less about video games as they get older, and more about politics." 
 Question: When do women love books best?
Output: at the age of 22.
Context: Flumazenil (Ro 15-1788) proved to be a very efficacious competitive antagonist of benzodiazepines that reliably counteracts their pharmacological actions within 1-2 min as could be demonstrated in clinical and EEG studies. In general, a total dose of 0.3-0.8 mg will be sufficient in clinical practice, avoiding side effects like nausea, tremor, sweating, or transient anxiety that could be observed when higher dosages were administered. Its therapeutic range is very high as could be demonstrated in experimental animal in which up to 8.000-fold the clinical dose was administered. The total volume of distribution (Vdes) amounts to nearly 1.000 ml/kg BW and the total clearance exceeds 1.200 ml/min, resulting in a biological half-life of less than 60 min. According to the benzodiazepine dosage and the rapid plasma concentration decline of flumazenil, in some cases a resedation could be observed. Hence, a careful observation of the antagonised patient on the ward is mandatory for 1.5-2 h, even if at first sight the antagonization seemed successful and the patient fully awake and cooperative. In anaesthesia, indications to administer flumazenil are adverse drug reactions and prolonged recovery after adequate benzodiazepine dosage. In intensive care medicine, the antagonist may be used in the treatment of benzodiazepine overdose as well as in the differential diagnosis of a coma of unknown origin. Additionally, the antagonist may be administered to interrupt benzodiazepine sedation e.g. for neurological examination. 
 Question: Which drug should be used as an antidote in benzodiazepine overdose?
Output: flumazenil
Context: Topographic maps represent the locations of geographical features, such as hills and valleys. Topographic maps use contour lines to show different elevations. A contour line is a line of equal elevation. If you walk along a contour line you will not go uphill or downhill. Topographic maps are also called contour maps. The rules of topographic maps are: Each line connects all points of a specific elevation. Contour lines never cross since a single point can only have one elevation. Every fifth contour line is bolded and labeled. Adjacent contour lines are separated by a constant difference in elevation (such as 20 ft or 100 ft). The difference in elevation is the contour interval, which is indicated in the map legend. Scales indicate horizontal distance and are also found on the map legend. Old Faithful erupting, Yellowstone Na- tional Park. While the Figure 1.1 isnt exactly the same view as the map at the top of this concept, it is easy to see the main features. Hills, forests, development, and trees are all seen around Old Faithful. A bathymetric map is like a topographic map with the contour lines representing depth below sea level, rather than height above. Numbers are low near sea level and become higher with depth. Kilauea is the youngest volcano found above sea level in Hawaii. On the flank of Kilauea is an even younger volcano called Loihi. The bathymetric map pictured in the Figure 1.2 shows the form of Loihi. Loihi volcano growing on the flank of Kilauea volcano in Hawaii. Black lines in the inset show the land surface above sea level and blue lines show the topography below sea level. A geologic map of the region around Old Faithful, Yellowstone National Park. A geologic map shows the geological features of a region (see Figure 1.3 for an example). Rock units are color- coded and identified in a key. Faults and folds are also shown on geologic maps. The geology is superimposed on a topographic map to give a more complete view of the geology of the region. Click image to the left or use the URL below. URL: 
 Question: topographic maps
Output: use contour lines to show different elevations
Context: Escort in Love (Italian: Nessuno mi puo giudicare) is a 2011 Italian comedy film directed by Massimiliano Bruno. 
 Question: The film Escort in Love was directed by whom?
Output: massimiliano bruno
Context: Have you ever been to the world's smallest bookstore? The World's Smallest Bookstore,whose official name is just these three words,sits quietly about 100 miles northeast of Toronto. The bookstore is about 10 feet by 10 feet,so it is easy to imagine how tiny it really is.The bookstore is open 24 hours a day.Inside the bookstore are various books,especially literary books and classic authors' works.So if you are looking for something less popular,you may get a bit disappointed there. Another special feature of this bookstore is that each book only costs three dollars.All the expenses are paid on the honor system,which means buyers should make a note of what they've bought and leave their money by themselves.So the tools of the trade in this bookstore are quite simple: pens,papers,light bulbs and a label-maker. In order to catch passers-by's attention,the billboards of the bookstore are several times bigger than the store itself.With these large eye-catchers,many people are willing to stop by and have a visit. 
 Question: What's the passage mainly about?
Output: the world's smallest bookstore.
Context: According to 2011 census of India, Kumbakonam had a population of 140,156 with a sex-ratio of 1,021 females for every 1,000 males, much above the national average of 929. A total of 12,791 were under the age of six, constituting 6,495 males and 6,296 females.The average literacy of the city was 83.21%, compared to the national average of 72.99%. There were a total of 9,519 workers, comprising 32 cultivators, 83 main agricultural labourers, 1,206 in house hold industries, 7,169 other workers, 1,029 marginal workers, 24 marginal cultivators, 45 marginal agricultural labourers, 212 marginal workers in household industries and 0 other marginal workers. 
 Question: According to the census, which group is larger: house hold industries or marginal cultivators?
Output: house hold industries
Context: Watanabe et al (Reports, 12 April 2013, p. 195) study the yeast SWR1/SWR-C complex responsible for depositing the histone variant H2A.Z by replacing nucleosomal H2A with H2A.Z. They report that reversal of H2A.Z replacement is mediated by SWR1 and related INO80 on an H2A.Z nucleosome carrying H3K56Q. Using multiple assays and reaction conditions, we find no evidence of such reversal of H2A.Z exchange. 
 Question: Which protein mediates the replacement of H2A by H2A.Z in the yeast Saccharomyces cerevisiae?
Output: swr1
Context: Inventors are always looking for ways to make our lives easier, greener and a whole lot more fun. Take a look at the following breakthroughs in science and technology. What in the world will inventors dream up next? Superhero Suit Have you ever dreamed of becoming a superhero? Dream no more. There's a real Iron Man suit, XOS 2, which instantly transforms the person wearing it. The suit provides the power to lift 200 pounds with ease and break slabs of wood with a single karate chop. It was designed to help the military with heavy lifting. One person in the suit could do the work of three soldiers. Up, Up and Away! It took him 30 years to develop it, and now Glen Martin's invention is ready to take off. The Martin Jetpack allows its operator to fly 8,000 feet into the air. Unfortunately, you can't soar through the skies too long. The jetpack holds only 30 minutes' worth of fuel. The aircraft will sell for $100,000. Hardworking Robot The EMIEW2 robot is the perfect office helper. Need a document delivered? No problem! It can also guide visitors to their destinations. The three-foot-tall robot can identify different human voices and respond to commands. One day, it may serve as a receptionist or a security guard. Green Machine Say goodbye to gasoline! The AirPod car runs on air power. That means this car won't pollute the environment. A high-pressure air tank can fill the car in minutes. The three-wheeler can travel about 130 miles between fill-ups. Beef Power All aboard the beef train! Amtrak's Heartland Flyer runs partly on fuel that is made from cow fat. The goal is to reduce carbon emissions by 10%. The train travels between Oklahoma City, Oklahoma, and Fort Worth, Texas. Robo-Guard EMILY is a robotic, four-foot-long buoy . She can swim through riptides at up to 24 miles per hour. Her inventor, Tony Mulligan, says that's 15 times as fast as human lifeguards! EMILY is powered by a tiny electric pump and operated by remote control. 
 Question: How many environment-friendly inventions are mentioned in the passage?
Output: three.
Context: For travellers who want to experience some of the history and mystery of the ancient world, here is a list of cool destinations for your next holiday. Angkor Wat, Cambodia Built in the 12th century, Angkor Wat (meaning "capital monastery") was a temple in the ancient Khmer capital city of Angkor. It is Cambodia's best-known tourist attraction and is famed for its beautiful architecture and reliefs. You'll need at least three days to fully discover the delights of this magnificent site. Machu Picchu, Peru Machu Picchu was built high in the Andes Mountains of South America by the Inca in the 15th century. Although well preserved its exact purpose is unknown. It is famous throughout the world not only for its incredible design but also for the natural beauty that surrounds it. Give yourself a week to explore this magnificent site. Stonehenge, England The entire Stonehenge site was constructed over thousands of years. But why and how it was built remains a mystery. As the weather can be pretty bleak in winter and the crowds huge in summer, we suggest autumn should be the best time to visit these monster rocks. Pompeii, Italy When Mount Vesuvius erupted in 79 A.D., Pompeii was buried under many layers of ash, preserving the city exactly as it was when the volcano erupted. Because so many objects were preserved, scientists and visitors are able to better understand daily life in the ancient Roman Empire. 
 Question: Which location offers the most direct view into daily life in the ancient world?
Output: pompeii.
Context: TODAY, Friday, November 12 JAZZ with the Mike Thomas Jazz Band at The Derby Arms. Upper Richmond Road West, Sheen. DISCO Satin Sounds Disco. Free at The Lord Napier, Mort lake High St., from 8a. m. to 8p. m. Tel: 682--1158. SATURDAY, November 13 JAZZ Lysis at The Bull's Head, Barnes. Admission 60p. MUSICAL HALL at The Star and Garter, Lower Richmond Road, Putney, provided by the Aba Daba Music Hall company. Good food and entertainment fair price. Tel: 789--6749. FAMILY night out? Join the sing-along at The Black Horse. Sheen Road, Richmond. JAZZ The John Bennett Big Band at The Bull's Head, Barnes. Admission 80p. THE DERBY ARMS, Upper Richmond Road West, give you Joe on the electric accordion . Tel: 789--4536 SUNDAY, November 14 DISCO Satin Sounds Disco, free at The Lord Napier, Mort Lake High Street, from 8 a. m. to 8 p. m. FOLK MUSIC at The Derby Arms. The Short Stuff and residents the Norman Chop Trio. Non-remembers 70p. Tel: 688--4626. HEAVY MUSIC with Tony Simon at The Bull, Upper Richmond Road West, East Sheen. THE DERBY ARMS, Upper Richmond Road West, give you Joe on the electric accordion. 
 Question: You want to enjoy the electric accordion on Saturday. Which telephone number do you have to ring to find out what time it starts?
Output: 789--4536.
Context: Azeffoun is bounded by the Mediterranean Sea on the north, the town of Ait Chafaa on the east, and the common Akerrou, Aghrib in the south and Iflissen in the west. 
 Question: Which is the body of water by Azeffoun?
Output: mediterranean sea
Context: Soviet troops approached the Lithuanian territory on December 12, 1918. About 5,000 of them were Lithuanians. Three divisions were employed: Pskov division , International Division , and 17th Division . The divisions did not have a common military commander. Later more units were sent from Russia. The soviets also recruited partisan groups behind the front lines. Soviet soldiers were poorly supplied and had to support themselves by requisitioning food, horses, and clothes from local residents. Lithuania could not offer serious resistance as at the time its army consisted only of about 3,000 untrained volunteers. Only local partisans, armed with weapons acquired from retreating Germans, offered brief resistance. Red Army captured one town after another: Zarasai and Svencionys , Utena , Rokiskis , Vilnius , Ukmerge and Panevezys , Siauliai , Telsiai . That accounted for about of the Lithuanian territory. The front somewhat stabilized when Soviet forces were stopped near the Venta River by Latvian and German units . Also Germans slowed down withdrawal of their troops after the Spartacist uprising was subdued on January 12. Southern Lithuania was a little better protected as Germans retreated from Ukraine through Hrodna. To prevent fights between retreating Germans and the Red Army, the Soviets and Germans signed a treaty on January 18. The treaty drew a temporary demarcation line that went through Daugai, Stakliskes, and 10 kilometres east of Kaisiadorys-Jonava-Kedainiai railway. That barred Bolshevik forces from directly attacking Kaunas, Lithuania's second-largest city. The Red Army would need to encircle Kaunas and attack through Alytus or Kedainiai. The operation to take Kaunas began on February 7. 
 Question: What happened first, Germans signed a treaty or the operation to take Kaunas began?
Output: germans signed a treaty
Context: Hoping to rebound from their road loss to the Patriots, the Rams went home for a Week 9 NFC West duel with the Arizona Cardinals. In the first quarter, St. Louis struck first as QB Marc Bulger completed an 80-yard TD pass to WR Derek Stanley. In the second quarter, the Cardinals responded with a vengeance as safety Antrel Rolle returned an interception 40 yards for a touchdown, kicker Neil Rackers got a 36-yard field goal, RB Tim Hightower got a 30-yard TD run, and former Rams QB Kurt Warner completed a 56-yard TD pass to WR Jerheme Urban. In the third quarter, Arizona increased its lead as Warner completed a 7-yard TD pass to WR Anquan Boldin. In the fourth quarter, the Rams tried to come back as Bulger completed a 3-yard TD pass to WR Torry Holt (with a failed 2-point conversion). However, the Cardinals flew away as Rackers nailed a 30-yard field goal. During the game, the Rams inducted former Head Coach Dick Vermeil (who helped the franchise win Super Bowl XXXIV) onto the Rams Ring of Honor. 
 Question: Who caught a 3 yard touchdown pass?
Output: torry holt
Context: Hoping to rebound from their road loss to the Patriots, the Rams went home for a Week 9 NFC West duel with the Arizona Cardinals. In the first quarter, St. Louis struck first as QB Marc Bulger completed an 80-yard TD pass to WR Derek Stanley. In the second quarter, the Cardinals responded with a vengeance as safety Antrel Rolle returned an interception 40 yards for a touchdown, kicker Neil Rackers got a 36-yard field goal, RB Tim Hightower got a 30-yard TD run, and former Rams QB Kurt Warner completed a 56-yard TD pass to WR Jerheme Urban. In the third quarter, Arizona increased its lead as Warner completed a 7-yard TD pass to WR Anquan Boldin. In the fourth quarter, the Rams tried to come back as Bulger completed a 3-yard TD pass to WR Torry Holt (with a failed 2-point conversion). However, the Cardinals flew away as Rackers nailed a 30-yard field goal. During the game, the Rams inducted former Head Coach Dick Vermeil (who helped the franchise win Super Bowl XXXIV) onto the Rams Ring of Honor. 
 Question: Who caught a 3 yard touchdown pass?
Output: wr torry holt
Context: Konstantinos Raktivan (Greek: ; 1865 -- 21 May 1935) was a Greek jurist and politician, who served as cabinet minister, as the de facto first Governor-General of Macedonia, president of the Athens Bar Association and of the Council of State, Speaker of the Hellenic Parliament and member and president of the Academy of Athens. 
 Question: Who led Konstantinos Raktivan?
Output: academy of athens
Context: A family in Guelph, Ontario is spending a year living "in 1982".They're doing it so their kids can see what life was like before technology like iPads, computers and even coffee machines was part of everyday life. They have stopped using all technology from their home and are relying on the things people would have used back in the 80s.There is a box at the front door where people can put their cell phones in, while they're visiting the family. Blair McMillan and his wife Morgan want their kids--Trey, 5, and Denton, 2 -- to have a year without technology. Instead of reading ereaders, they are reading books. Instead of using a GPS, they used paper maps. The home the family is living in was built in the 1980s.Even the way they dress and style their hair is from the 80s. The whole idea started when young Trey was called to come outside. He didn't because he was busy playing on the iPad. That's why his dad thought of the idea of living "in 1982" for a year. The family plans to live like "it's 1982" until April next year. To them, one of the hardest things was giving up their cell phones. 
 Question: Who made the family have the idea of living "in 1982"?
Output: young trey.
Context: The Steelers stayed home for a 3-game home stand and for a Sunday Night duel against the Ravens. The Ravens scored first when Joe Flacco hooked up with Torrey Smith 35-yard TD pass to take a 7-0 lead for the only score of the first quarter. In the 2nd quarter, the Steelers managed to tie the game up when Ben Roethlisberger found Le'Veon Bell on a 5-yard TD pass for a 7-7 game. They eventually took the lead when Roethlisberger found Martavis Bryant on a 19-yard TD pass to make it a 14-7 game. The Ravens came within 4 as Justin Tucker kicked a 46-yard field goal to make it 14-10 game. However, the Steelers would manage to go ahead by 12 before halftime when Roethlisberger found Markus Wheaton on a 47-yard TD pass followed by a successful 2-point conversion for a 22-10 lead at halftime. After a scoreless 3rd quarter, the Steelers came out strong and went back to work in the 4th when Roethlisberger found Antonio Brown on a 54-yard TD pass making the score 29-10. The Ravens responded with a big play as Jacoby Jones ran a 108-yard kickoff return for a TD to make it a 29-17 game. Roethlisberger found Bryant again on an 18-yard TD pass to make the score 36-17. This was followed by the Ravens trying their hand at coming back when Flacco found Crockett Gillmore on a 1-yard TD pass (with a failed 2-point conversion) for a 36-23 score. But the Steelers were able to seal the game when Roethlisberger found Matt Spaeth on a 33-yard TD pass for a final score of 43-23. A week after passing for a franchise-record six touchdowns against Indianapolis, Roethlisberger duplicated the feat to lead Pittsburgh to its third consecutive win. The 12 touchdown passes over the last two games broke the NFL record of 11 set by Tom Flores for Oakland in the AFL in 1963 and matched by New England's Tom Brady in 2007. 
 Question: Who caught the longest touchdown pass?
Output: antonio brown
Context: Motion of the median nerve was compared on an axial ultrasonographic image in the mid-carpal tunnel in 30 wrists of 15 women with bilateral idiopathic carpal tunnel syndrome and 30 wrists of 15 healthy women. During passive flexion and extension of the index finger, the control wrists had transverse sliding of the nerve beneath the flexor retinaculum (1.75 +/- 0.49 mm), which was regarded as a physiological phenomenon. In contrast, the wrists of patients with carpal tunnel syndrome had significantly less sliding (0.37 +/- 0.34 mm; P = 0.0001), which indicates that physiological motion of the nerve is restricted. This decrease in nerve mobility may be of significance in the pathophysiology of carpal tunnel syndrome. 
 Question: What nerve is involved in carpal tunnel syndrome?
Output: median
Context: Histone H3 lysine 9 (H3K9) methylation is a major component of gene regulation and chromatin organization. SUV39H1 methylates H3K9 at the pericentric heterochromatin region and participates in the maintenance of genome stability. In this study, a recombinant purified SUV39H1 is used for substrate specificity and steady-state kinetic analysis with peptides representing the un- or dimethylated lysine 9 histone H3 tail or full-length human recombinant H3 (rH3). Recombinant SUV39H1 methylated its substrate via a nonprocessive mechanism. Binding of either peptide or AdoMet first to the enzyme made a catalytically competent binary complex. Product inhibition studies with SUV39H1 showed that S-adenosyl-l-homocysteine is a competitive inhibitor of S-adenosyl-l-methionine and a mixed inhibitor of substrate peptide. Similarly, the methylated peptide was a competitive inhibitor of the unmethylated peptide and a mixed inhibitor of AdoMet, suggesting a random mechanism in a bi-bi reaction for recombinant SUV39H1 in which either substrate can bind to the enzyme first and either product can release first. The turnover numbers (k(cat)) for the H3 tail peptide and rH3 were comparable (12 and 8 h(-)(1), respectively) compared to the value of 1.5 h(-)(1) for an identical dimethylated lysine 9 H3 tail peptide. The Michaelis constant for the methylated peptide (K(m)(pep)) was 13-fold lower compared to that of the unmethylated peptide. The Michaelis constants for AdoMet (K(m)(AdoMet)) were 12 and 6 microM for the unmethylated peptide substrate and rH3, respectively. A reduction in the level of methylation was observed at high concentrations of rH3, implying substrate inhibition. Deletion of the chromodomain or point mutation of the conserved amino acids, W64A or W67A, of SUV39H1 impaired enzyme activity despite the presence of an intact catalytic SET domain. Thus, SUV39H1 utilizes both the chromodomain and the SET domain for catalysis. 
 Question: What is the characteristic domain of histone methyltransferases?
Output: set domain
Context: Urgyen Tsomo (1897--1961) was a prominent Tibetan Buddhist female master who was known as the Great Dakini of Tsurphu (Tsurpu Khandro Chenmo). 
 Question: What is the gender Urgyen Tsomo is known by?
Output: female
Context: As a student leader at George Washington University in the 1970s, Mowahid Shah was Editor of the ''Harbinger'', a student publication. 
 Question: What college did Mowahid Shah go to?
Output: george washington university
Context: After a win at Cleveland, the Steelers traveled to Baltimore to take on the Ravens in what would be the Thanksgiving Primetime Game and of course their first game on Thanksgiving Day since 1998. The Ravens drew first blood as Joe Flacco found Torrey Smith on a 7-yard pass to make the score 7-0 in the first quarter. In then 2nd quarter, Justin Tucker nailed a 43-yard field goal for a 10-0 halftime lead. After the break, the Ravens went back to work in the 3rd quarter as Tucker nailed a 34-yard field goal for a 13-0 lead. The Steelers finally got on the board asBen Roethlisberger found Emmanuel Sanders on an 8-yard touchdown pass for a 13-7 score. The Ravens then pulled away as Tucker kicked yet another field goal putting his team ahead by 9, 16-7. In the 4th quarter, Tucker kicked yet another field goal this one from 45 yards out for a score of 19-7. The Steelers managed to draw within 5 points 19-14 when Le'Veon Bell ran for a 1-yard touchdown. Tucker then kicked a 48-yard field goal to make the score 22-14. The Steelers started their comeback attempt as Roethlisberger found Jerricho Cotchery on a 1-yard touchdown pass for a 22-20 score. After this, they tried the 2-point conversion to tie the game and send it into OT, but they would come up short and miss the conversion with 1:03 left in the game. This dropped the team to 5-7 and 3rd place in the AFC North. Also they dropped to 2-5 on Thanksgiving. 
 Question: Which team went scoreless in the first quarter?
Output: steelers
Context: The State of Law Coalition (Arabic: I'tilaf Dawlat al-Qanun) also known as Rule of Law Coalition is an Iraqi political coalition formed for the Iraqi governorate elections, 2009 by the Prime Minister of Iraq at the time, Nouri al-Maliki, of the Islamic Dawa Party. 
 Question: Who led State of Law Coalition?
Output: nouri al-maliki
Context: The Panthers beat the Tampa Bay Buccaneers 26-24, with the help of two touchdowns (1 receiving, 1 rushing) from former Bucs WR Keyshawn Johnson and four long field goals from Kicker John Kasay. Kasay was the first kicker to go 4 for 4 in a game on field goals more than 46 yards. Steve Smith returned, catching 7 passes for 102 yards, and QB Jake Delhomme threw his first touchdown pass of the season. With their first victory, the Panthers are 1-2. 
 Question: What was the final score?
Output: 26-24
Context: Amyloid precursor protein (APP) is strongly related to the onset of Alzheimer's disease. It possesses cleavage sites for beta- and gamma-secretases, and the resulting cleaved products (amyloid-beta peptides) are capable of causing neurotoxicity. Such cleavage is promoted by the Swedish and London mutations (APPSwe/Lon) inside the APP gene. Here, we characterized APPSL transgenic mice (APPSL-Tg) to determine the effects of this mutation. We observed that both the amount of insoluble amyloid-beta and the ratio of amyloid-beta 42/40 increased promptly in the brain during 6-16 months of age. Amyloid-beta plaques were observed in whole brain sections at 12 months. In contrast, the spatial memory assessed by the Morris water maze task was already impaired at 3 months, which suggested that the APPSL-Tg mice may represent an early-onset model of familial Alzheimer's disease. Furthermore, the levels of LAMP-1, a marker protein of lysosome, increased in the brain at 28 months. Such LAMP-1 protein was detected around the amyloid-beta plaques at the hippocampal regions of the APPSL-Tg mice. Our results suggested that the increase in LAMP-1 was enhanced by the accumulation of amyloid-beta occurring during aging. Our findings coincided with the pathological hallmarks of Alzheimer's disease. 
 Question: Which disease the London mutation involved in?
Output: alzheimer's disease
Context: Amyloid precursor protein (APP) is strongly related to the onset of Alzheimer's disease. It possesses cleavage sites for beta- and gamma-secretases, and the resulting cleaved products (amyloid-beta peptides) are capable of causing neurotoxicity. Such cleavage is promoted by the Swedish and London mutations (APPSwe/Lon) inside the APP gene. Here, we characterized APPSL transgenic mice (APPSL-Tg) to determine the effects of this mutation. We observed that both the amount of insoluble amyloid-beta and the ratio of amyloid-beta 42/40 increased promptly in the brain during 6-16 months of age. Amyloid-beta plaques were observed in whole brain sections at 12 months. In contrast, the spatial memory assessed by the Morris water maze task was already impaired at 3 months, which suggested that the APPSL-Tg mice may represent an early-onset model of familial Alzheimer's disease. Furthermore, the levels of LAMP-1, a marker protein of lysosome, increased in the brain at 28 months. Such LAMP-1 protein was detected around the amyloid-beta plaques at the hippocampal regions of the APPSL-Tg mice. Our results suggested that the increase in LAMP-1 was enhanced by the accumulation of amyloid-beta occurring during aging. Our findings coincided with the pathological hallmarks of Alzheimer's disease. 
 Question: Which disease the London mutation involved in?
Output: ad
Context: POV-Ray also could be ported to any platform which has a compatible C++ compiler. 
 Question: What is the programming language for POV-Ray?
Output: c++
Context: MicroRNAs (miRNAs) are 21 nt RNAs that regulate many biological processes in plants by mediating translational inhibition or cleavage of target transcripts. Arabidopsis mutants defective in miRNA biogenesis have overlapping and highly pleiotropic phenotypes including serrated leaves and ABA hypersensitivity. Recent evidence indicates that miRNA genes are transcribed by RNA polymerase II (Pol II). Since Pol II transcripts are capped, we hypothesized that CBP (cap-binding protein) 20 and 80 may bind to capped primary miRNA (pri-miRNA) transcripts and play a role in their processing. Here, we show that cbp20 and cbp80 mutants have reduced miRNA levels and increased pri-miRNA levels. Co-immunoprecipitation experiments revealed that pri-miRNAs 159, 166, 168 and 172 could be associated with CBP20 and CBP80. We found that CBP20 and CBP80 are stabilized by ABA by a post-translational mechanism, and these proteins are needed for ABA induction of miR159 during seed germination. The lack of miR159 accumulation in ABA-treated seeds of cbp20/80 mutants leads to increased MYB33 and MYB101 transcript levels, and presumably higher levels of these positive regulators result in ABA hypersensitivity. Genetic and molecular analyses show that CBP20 and 80 have overlapping function in the same developmental pathway as SE and HYL1. Our results identify new components in miRNA biogenesis. 
 Question: Which polymerase transcribes pri-miRNAs?
Output: rnapii
Context: MicroRNAs (miRNAs) are 21 nt RNAs that regulate many biological processes in plants by mediating translational inhibition or cleavage of target transcripts. Arabidopsis mutants defective in miRNA biogenesis have overlapping and highly pleiotropic phenotypes including serrated leaves and ABA hypersensitivity. Recent evidence indicates that miRNA genes are transcribed by RNA polymerase II (Pol II). Since Pol II transcripts are capped, we hypothesized that CBP (cap-binding protein) 20 and 80 may bind to capped primary miRNA (pri-miRNA) transcripts and play a role in their processing. Here, we show that cbp20 and cbp80 mutants have reduced miRNA levels and increased pri-miRNA levels. Co-immunoprecipitation experiments revealed that pri-miRNAs 159, 166, 168 and 172 could be associated with CBP20 and CBP80. We found that CBP20 and CBP80 are stabilized by ABA by a post-translational mechanism, and these proteins are needed for ABA induction of miR159 during seed germination. The lack of miR159 accumulation in ABA-treated seeds of cbp20/80 mutants leads to increased MYB33 and MYB101 transcript levels, and presumably higher levels of these positive regulators result in ABA hypersensitivity. Genetic and molecular analyses show that CBP20 and 80 have overlapping function in the same developmental pathway as SE and HYL1. Our results identify new components in miRNA biogenesis. 
 Question: Which polymerase transcribes pri-miRNAs?
Output: rna polymerase ii
Context: BugSat 1 was launched from Dombarovsky (air base) site 13, Russia, on 19 June 2014 by a Dnepr-1 rocket. 
 Question: What date was BugSat 1 launched?
Output: 19 june 2014
Context: 1016 Anitra, provisional designation 1924 QG, is a main-belt asteroid discovered by German astronomer Karl Wilhelm Reinmuth at Heidelberg-Konigstuhl State Observatory on January 31, 1924. 
 Question: Who discovered 1016 Anitra?
Output: karl wilhelm reinmuth
Context: Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are characterized by abnormal deposition of -synuclein aggregates in many regions of the central and peripheral nervous systems. Accumulating evidence suggests that the -synuclein pathology initiates in a few discrete regions and spreads to larger areas in the nervous system. Recent pathological studies of PD patients have raised the possibility that the enteric nervous system is one of the initial sites of -synuclein aggregation and propagation. Here, we evaluated the induction and propagation of -synuclein aggregates in the enteric nervous system of the A53T -synuclein transgenic mice after injection of human brain tissue extracts into the gastric walls of the mice. Western analysis of the brain extracts showed that the DLB extract contained detergent-stable -synuclein aggregates, but the normal brain extract did not. Injection of the DLB extract resulted in an increased deposition of -synuclein in the myenteric neurons, in which -synuclein formed punctate aggregates over time up to 4 months. In these mice, inflammatory responses were increased transiently at early time points. None of these changes were observed in the A53T mice injected with saline or the normal brain extract, nor were these found in the wild type mice injected with the DLB extract. These results demonstrate that pathological -synuclein aggregates present in the brain of DLB patient can induce the aggregation of endogenous -synuclein in the myenteric neurons in A53T mice, suggesting the transmission of synucleinopathy lesions in the enteric nervous system. 
 Question: Which disease of the central nervous system is characterized by the presence of Lewy bodies?
Output: parkinson's disease (pd)
Context: The Legend of Neil is a comedy web series distributed by Comedy Central's partner Atom.com and is a parody of the Nintendo game The Legend of Zelda. 
 Question: The The Legend of Neil is based upon what?
Output: the legend of zelda
Context: In order to determine the prevalence of latent infection due to Mycobacterium tuberculosis in drug users and to provide centres for drug users with a practical tool for tuberculosis screening, 237 drug users were subjected to the Monotest and, for reference purposes, to the Mantoux test. The overall prevalence of subjects with a tuberculin skin reaction size > or = 5 mm in the Mantoux test was 25.7%; utilizing a cut-off of > or = 10 mm, the prevalence was 11.4%. Irrespective of cut-off, the Monotest showed a sensitivity of > 90% and a specificity of > 80%. At a prevalence of 25.7%, and with cut-offs of > or = 5 or > or = 10 mm, the positive predictive value was 83% or 62.2%, respectively. Irrespective of cut-off, the negative predictive value was > 97%. In conclusion, the Monotest proved satisfactory as a tool for epidemiological screening in a population with a high prevalence for latent tuberculosis, namely drug users. 
 Question: The Mantoux test detects what latent infection/disease?
Output: tuberculosis
Context: Riseberga Abbey (Swedish: Riseberga kloster), was a Cistercian nunnery in Sweden, in operation from cirka 1180 until 1534. 
 Question: What year did Riseberga Abbey dissolve?
Output: 1534
Context: From 1995 to 2011, the Horizon League has sent 24 teams to the NCAA Mens Division I Basketball Tournament. Those clubs have produced 22 wins in those 14 years, including five "Sweet 16" appearances, making the Horizon League the only Mid-major conference with Sweet 16 participants in at least five of the last nine tournaments (2003, 2005, 2007, 2010 and 2011). Four schools from the conference have produced "modern-day" Sweet 16 appearances - Loyola (1985 NCAA Mens Division I Basketball Tournament), Xavier (1990 NCAA Mens Division I Basketball Tournament), Butler (2003 NCAA Mens Division I Basketball Tournament, 2007 NCAA Mens Division I Basketball Tournament, 2010 NCAA Mens Division I Basketball Tournament and 2011 NCAA Mens Division I Basketball Tournament), and Milwaukee (2005 NCAA Mens Division I Basketball Tournament). The Horizon League has compiled a 15-8 record in the past five years in the NCAA tournament, ranking tops among all NCAA Division I conferences for winning percentage in that span. Butler appeared in the mens national championship game in both 2009-10 Butler Bulldogs mens basketball team and 2010-11 Butler Bulldogs mens basketball team, losing both times. Since the NCAA began seeding teams in 1979, Loyolas 4 seed in the 1985 tournament is the best for a Horizon League team. The Horizon League currently holds the best winning percentage among non-Automatic Qualifying conference in the mens NCAA basketball Tournament (.488, 7th overall amongst the 31 Division I conferences). 
 Question: Which school form the conference produced modern day Sweet 16 appearances in 1985?
Output: loyola
Context: In 1997 the Kymi Province was merged with the Uusimaa Province and the southern parts of the Hame Province into the new Southern Finland Province. 
 Question: What was replaced Kymi Province?
Output: southern finland province
Context: Antara Mali was born in Mumbai on 1 July 1979, to a kushwaha family India photographer Jagdish Mali. 
 Question: What is the name of Antara Mali father?
Output: jagdish mali
Context: Pocos de Caldas Futebol Clube played their home games at Estadio Dr. Ronaldo Junqueira, nicknamed Ronaldao. 
 Question: What arena did Pocos de Caldas Futebol Clube play in?
Output: ronaldão
Context: The War of the Spanish Succession was a European conflict of the early 18th century, triggered by the death of the childless Charles II of Spain in November 1700. His closest heirs were members of the Austrian Habsburg and French Bourbon families; acquisition of an undivided Spanish Empire or Monarchy by either threatened the European balance of power. Charles left his throne to Louis XIV's grandson Philip who was proclaimed King of Spain on 16 November 1700. Disputes over the separation of the Spanish and French crowns, division of territories and commercial rights led to war in 1701 between the Bourbons of France and Spain and the Grand Alliance, whose candidate was Archduke Charles, younger son of Habsburg Emperor Leopold. By 1710, fighting was deadlocked; Allied victories in Italy and the Low Countries had driven the French back to their borders but they could not achieve a decisive breakthrough while Philip was secure in Spain. When Archduke Charles succeeded his brother Joseph I as Emperor in 1711, Britain effectively withdrew, forcing its Allies to make peace and leading to the 1713 Treaty of Utrecht, followed in 1714 with Rastatt and Baden. Philip was confirmed as King of Spain and renounced the French throne; Spain retained the bulk of its pre-war territories outside Europe with their European territories divided between Austria, Britain and Savoy. Longer term impacts included Britain's emergence as the leading maritime and commercial power, the beginning of the decline of the Dutch Republic, the creation of a centralised Spanish state and the acceleration of the break-up of the Holy Roman Empire. 
 Question: Who was Emperor first, Archduke Charles or his brother Joseph I?
Output: archduke charles
Context: Our clothes are a powerful tool that can make us feel better about ourselves. One way in which this works is by wearing different color1s of clothes. Normally when we are sad, we will wear dark color1ed clothes. Oppositely, when we are happy, we often choose to wear brightly color1ed clothes. The reason for this is that our choice of color1 mirrors is how we are feeling. Those who don't believe in the idea are often heard saying, "if only this truly worked". Well in reply to those people, there has been a lot of research into what happens to someone's feelings when they are asked to wear just one color1 of clothes. It has been proven that if we wear particular color1s of clothes they can change our feelings. Suppose we are feeling sad, if we wear black we may begin to feel worse. However, if we wear green, red or yellow, we may begin to feel better. Each color1 is said to have its own healing power. So remember, if you are not feeling your best, you can always try out some different color1ed clothes. If one color1 has no effect on your feelings, maybe another will. 
 Question: What's the author's attitude toward "wearing particular color1s of clothes can change our feelings"?
Output: believe.
Context: Edward Julius Detmold (21 November 1883 Putney, Wandsworth, Surrey - 1 July 1957 Montgomery) and his twin brother Charles Maurice Detmold (1883-1908) were prolific Victorian book illustrators. 
 Question: What is Edward Julius Detmold's brothers name?
Output: maurice detmold
Context: Frieda Belinfante (born May 10, 1904, Amsterdam -- died April 26, 1995, Santa Fe, New Mexico) was a Dutch cellist, conductor, a prominent lesbian and a member of the Dutch Resistance during World War II. After the war, Belinfante immigrated to the United States and continued her career in music. 
 Question: What city did Frieda Belinfante live when he died?
Output: santa fe