niryuu/sni-each-converted huggingface dataset:
Context: There are about 27,000 species of bony fish ( Figure 1.1), which are divided into two classes: ray-finned fish and lobe-finned fish. Most bony fish are ray-finned. These thin fins consist of webs of skin over flexible spines. Lobe- finned fish, on the other hand, have fins that resemble stump-like appendages. Fins of bony fish: ray fin (left) and lobe fin (right). Most fish are bony fish, making them the largest group of vertebrates in existence today. They are characterized by: 1. A head and pectoral girdles (arches supporting the forelimbs) that are covered with bones derived from the skin. 2. A lung or swim bladder, which helps the body create a balance between sinking and floating by either filling up with or emitting gases such as oxygen. Controlling the volume of this organ helps fish control their depth. 3. Jointed, segmented rods supporting the fins. 4. A cover over the gill called the operculum, which helps them breathe without having to swim. 5. The ability to see in color, unlike most other fish. Most vertebrates are ray-finned fish, with close to 27,000 known species. By comparison, there are "only" about 10,000 species of birds. The ray-finned fish have fin rays, with fins supported by bony spines known as rays. The ray-finned fish are the dominant class of vertebrates, with nearly 99% of fish falling into this category. They live in all aquatic environments, from freshwater and marine environments from the deep sea to the highest mountain streams. The lobe-finned fish are characterized by fleshy lobed fins, as opposed to the bony fins of the ray-finned fish. There are two types of living lobe-finned fish: the coelacanths and the lungfish. The pectoral and pelvic fins have joints resembling those of tetrapod (four-limbed land vertebrates) limbs. These fins evolved into legs of amphibians, the first tetrapod land vertebrates. They also possess two dorsal fins with separate bases, as opposed to the single dorsal fin of ray-finned fish. All lobe-finned fishes possess teeth covered with true enamel. The lungfish also possess both gills and lungs, solidifying this class as the ancestors of amphibians. The ocean sunfish is the most massive bony fish in the world, up to 11 feet long and weighing up to 5,070 pounds ( Figure 1.2). Other very large bony fish include the Atlantic blue marlin, the black marlin, some sturgeon species, the giant grouper, and the goliath grouper. The long-bodied oarfish can easily be over 30 feet long, but is not nearly as massive as the ocean sunfish. In contrast, the dwarf pygmy goby measures only 0.6 inches. Fish can also be quite valuable. In January 2013, at an auction in Tokyos Tsukiji fish market, a 222-kilogram (489-pound) tuna caught off northeastern Japan sold for 155.4 million yen, which is $1,760,000. An ocean sunfish, the most massive bony fish in the world, can reach up to 11 feet long and weigh up to 5,070 pounds! 
 Question: most fish are what type?
Output: ray-finned fish
Context: Vivi Mac, an amazing artist from France, can use nearly any kind of food to create detailed celebrity portraits .Although she has yet to _ her short-lived work of arts in a proper art gallery, Vivi Mac has already made a name for herself online. We've seen some amazing food artists in the past, but none are quite like this one .Karen Eland is a master coffee painter, Elisabetta Rogai uses wine as her medium ,Kelly McCollam uses food colouring to recreat classic paintings, but the self-taught Vivi Mac can take anything from chewing gum to milk and turn it into a fantastic portrait When working with liquids, Mac uses a simple plastic straw and her hands to guide the unusual .mediums around a plastic plate which acts as a painting. Just how she manages to capture the finest facial features is still a mistery to me, and I've seen videos of her doing it many times, Vivi Mac has never attended art school. She only used online resources like blogs and facebook to learn the basics of drawing and painting. She started out working with pens and paper, but soon realized drawing wasn't just creative enough for her. She got into speed painting and body painting, posting videos of her works on You Tube, but it wasn't until she began experimenting with different kinds of foods that her art got serious coverage. Photos and videos of her eatable celebrity portraits, like Bruce Lee in milk Ice Cube in crushed ice or Amy Winehouse in wine, became popular on the French inter-webs and changed Vivi Mac into an online celebrity. 
 Question: In which section of a website are we most likely to find the passage?
Output: art
Context: City Reign are an indie rock band from Manchester, England. 
 Question: From what city is the band City Reign?
Output: manchester
Context: Sometimes, the urinary system ( Figure 1.1) is called the excretory system. But the urinary system is only one part of the excretory system. Recall that the excretory system is also made up of the skin, lungs, and large intestine, as well as the kidneys. The urinary system is the organ system that makes, stores, and gets rid of urine. 1. As you can see above ( Figure 1.1), the kidneys are two bean-shaped organs. Kidneys filter and clean the blood and form urine. They are about the size of your fists and are found near the middle of the back, just below your ribcage. 2. Ureters are tube-shaped and bring urine from the kidneys to the urinary bladder. 3. The urinary bladder is a hollow and muscular organ. It is shaped a little like a balloon. It is the organ that collects urine. 4. Urine leaves the body through the urethra. The kidneys filter the blood that passes through them, and the urinary bladder stores the urine until it is released from the body. Urine is a liquid that is formed by the kidneys when they filter wastes from the blood. Urine contains mostly water, but it also contains salts and nitrogen-containing molecules. The amount of urine released from the body depends on many things. Some of these include the amount of fluid and food a person consumes and how much fluid they have lost from sweating and breathing. Urine ranges from colorless to dark yellow but is usually a pale yellow color. Light yellow urine contains mostly water. The darker the urine, the less water it contains. The urinary system also removes a type of waste called urea from your blood. Urea is a nitrogen-containing molecule that is made when foods containing protein, such as meat, poultry, and certain vegetables, are broken down in the body. Urea and other wastes are carried in the bloodstream to the kidneys, where they are removed and form urine. 
 Question: what brings urine from the kidneys to the urinary bladder?
Output: the ureters
Context: 9767 Midsomer Norton (1992 EB1) is an outer main-belt asteroid discovered on March 10, 1992 by Duncan Steel at Siding Spring. 
 Question: Who made the discovery of 9767 Midsomer Norton?
Output: duncan steel
Context: Mutations of presenilin 1 (PS1) causing Alzheimer's disease selectively increase the secretion of the amyloidogenic betaA4(1-42), whereas knocking out the gene results in decreased production of both betaA4(1-40) and (1-42) amyloid peptides (De Strooper et al. 1998). Therefore, PS1 function is closely linked to the gamma-secretase processing of the amyloid precursor protein (APP). Given the ongoing controversy on the subcellular localization of PS1, it remains unclear at what level of the secretory and endocytic pathways PS1 exerts its activity on APP and on the APP carboxy-terminal fragments that are the direct substrates for gamma-secretase. Therefore, we have reinvestigated the subcellular localization of endogenously expressed PS1 in neurons in vitro and in vivo using confocal microscopy and fine-tuned subcellular fractionation. We show that uncleaved PS1 holoprotein is recovered in the nuclear envelope fraction, whereas the cleaved PS fragments are found mainly in post-ER membranes including the intermediate compartment (IC). PS1 is concentrated in discrete sec23p- and p58/ERGIC-53-positive patches, suggesting its localization in subdomains involved in ER export. PS1 is not found to significant amounts beyond the cis-Golgi. Surprisingly, we found that APP carboxy-terminal fragments also coenrich in the pre-Golgi membrane fractions, consistent with the idea that these fragments are the real substrates for gamma-secretase. Functional evidence that PS1 exerts its effects on gamma-secretase processing of APP in the ER/IC was obtained using a series of APP trafficking mutants. These mutants were investigated in hippocampal neurons derived from transgenic mice expressing PS1wt or PS1 containing clinical mutations (PS1(M146L) and PS1(L286V)) at physiologically relevant levels. We demonstrate that the APP-London and PS1 mutations have additive effects on the increased secretion of betaA4(1-42) relative to betaA4(1-40), indicating that both mutations operate independently. Overall, our data clearly establish that PS1 controls gamma(42)-secretase activity in pre-Golgi compartments. We discuss models that reconcile this conclusion with the effects of PS1 deficiency on the generation of betaA4(1-40) peptide in the late biosynthetic and endocytic pathways. 
 Question: Which disease the London mutation involved in?
Output: alzheimer's disease
Context: Mutations of presenilin 1 (PS1) causing Alzheimer's disease selectively increase the secretion of the amyloidogenic betaA4(1-42), whereas knocking out the gene results in decreased production of both betaA4(1-40) and (1-42) amyloid peptides (De Strooper et al. 1998). Therefore, PS1 function is closely linked to the gamma-secretase processing of the amyloid precursor protein (APP). Given the ongoing controversy on the subcellular localization of PS1, it remains unclear at what level of the secretory and endocytic pathways PS1 exerts its activity on APP and on the APP carboxy-terminal fragments that are the direct substrates for gamma-secretase. Therefore, we have reinvestigated the subcellular localization of endogenously expressed PS1 in neurons in vitro and in vivo using confocal microscopy and fine-tuned subcellular fractionation. We show that uncleaved PS1 holoprotein is recovered in the nuclear envelope fraction, whereas the cleaved PS fragments are found mainly in post-ER membranes including the intermediate compartment (IC). PS1 is concentrated in discrete sec23p- and p58/ERGIC-53-positive patches, suggesting its localization in subdomains involved in ER export. PS1 is not found to significant amounts beyond the cis-Golgi. Surprisingly, we found that APP carboxy-terminal fragments also coenrich in the pre-Golgi membrane fractions, consistent with the idea that these fragments are the real substrates for gamma-secretase. Functional evidence that PS1 exerts its effects on gamma-secretase processing of APP in the ER/IC was obtained using a series of APP trafficking mutants. These mutants were investigated in hippocampal neurons derived from transgenic mice expressing PS1wt or PS1 containing clinical mutations (PS1(M146L) and PS1(L286V)) at physiologically relevant levels. We demonstrate that the APP-London and PS1 mutations have additive effects on the increased secretion of betaA4(1-42) relative to betaA4(1-40), indicating that both mutations operate independently. Overall, our data clearly establish that PS1 controls gamma(42)-secretase activity in pre-Golgi compartments. We discuss models that reconcile this conclusion with the effects of PS1 deficiency on the generation of betaA4(1-40) peptide in the late biosynthetic and endocytic pathways. 
 Question: Which disease the London mutation involved in?
Output: ad
Context: Simtek Grand Prix, the racing team, launched in 1993 and competed in the 1994 and 1995 seasons achieving a best result of ninth place. 
 Question: On what date did Simtek end?
Output: 1995
Context: The Gruffalo is a children's book by writer and playwright Julia Donaldson, illustrated by Axel Scheffler, that tells the story of a mouse, the protagonist of the book, taking a walk in a European forest. 
 Question: What person illustrated The Gruffalo?
Output: axel scheffler
Context: Progress M-10 was launched at 00:05:25 GMT on 17 October 1991, atop a Soyuz-U2 carrier rocket flying from Site 1/5 at the Baikonur Cosmodrome. 
 Question: What was the date Progress M-10 was launched?
Output: 17 october 1991
Context: In Week 8, the Bears donned their 1940s throwback uniforms against the Carolina Panthers, who had the worst record in the NFC. The Bears scored first on Matt Forte's 13-yard touchdown run, which would be countered by Justin Medlock's 34-yard field goal. The Panthers then took the lead on Louis Murphy's fumble recovery; Panthers quarterback Cam Newton ran with the ball, and lost the ball when Bears safety Major Wright tackled him at the 1-yard line. The ball rolled into the endzone, where Murphy recovered it. Medlock would then kick three more field goals, and by the fourth quarter, the Panthers led 19-7. The tide eventually turned when Panthers punter Brad Nortman shanked a 6-yard punt, and Jay Cutler hit Kellen Davis on a 12-yard touchdown pass with less than seven minutes left in the game. On the first play of the Panthers' next drive, Tim Jennings intercepted Newton and returned the pick 25 yards to regain the lead 20-19, after Cutler's two-point conversion passing attempt was intercepted. Medlock later kicked another field goal to reclaim the lead 22-20 with 2:27 left in the game. Cutler would lead the Bears downfield, and Gould kicked a 41-yard field goal as time expired to give Chicago the victory. The kick was Gould's tenth game-winning field goal, and the first since 2010. 
 Question: How made more field goals, Justin Medlock or Robbie Gould?
Output: justin medlock
Context: Urkhao Gwra Brahma is a Member of the Parliament of India representing Assam in the Rajya Sabha, the upper house of the Indian Parliament. 
 Question: What is Urkhao Gwra Brahma's country of original?
Output: india
Context: Between 1911 and 1912, over 1,000 Somalis from Mogadishu, the then capital of Italian Somaliland, served as combat units along with Eritrean and Italian soldiers in the Italo-Turkish War. Most of the troops stationed never returned home until they were transferred back to Italian Somaliland in preparation for the invasion of Ethiopia in 1935. The first disembarkation of Italian troops occurred on October 10. The Italian contingent of 20,000 troops was deemed sufficient to accomplish the conquest at the time. Tobruk, Derna and Khoms were easily conquered, but the same was not true for Benghazi. The first true setback for the Italian troops happened on October 23, when poor placement of the troops near Tripoli led them to be almost completely encircled by more mobile Arab cavalry, backed by some Turkish regular units. The attack was portrayed as a simple revolt by the Italian press, but it nearly annihilated much of the small Italian expeditionary corps. The corps was consequently enlarged to 100,000 men who had to face 20,000 Arabs and 8,000 Turks. The war turned into one of position. Even some of the earliest examples of utilisation in modern warfare of armoured cars and air power by the Italian forces had little effect on the initial outcome. However, the war was notable for the first military use of heavier-than-air craft. Capitano Carlo Piazza flew the first military reconnaissance flight on 23 October 1911. A week later, Sottotenente Giulio Gavotti dropped four grenades on Taguira and Ain Zara in history's first aerial bombing. 
 Question: In the Italo-Turkish War who was the difficult to conquer for the Italians, Tobruk, Derna, Khoms or Benghazi?
Output: benghazi
Context: Though Chad Pennington was active and in uniform for the Jets, the team erred on the side of caution due to injured right ankle, instead starting second-year backup Kellen Clemens, who was making his first career start. The Ravens' defense welcomed him rudely on his first drive with an interception by Ed Reed. The Ravens were able to attain good field position consistently throughout the first half, and quarterback Kyle Boller (who himself was starting in place of an injured starting quarterback, Steve McNair), capitalized with a two-yard touchdown to Willis McGahee late in the first quarter. The teams traded field goals to start the second quarter; Jets kicker Mike Nugent hit a 50-yard field goal, followed by Matt Stover hitting a 28-yard attempt for the Ravens. After Stover missed a 46-yard try, the Jets tried to respond with Nugent attempting a 52-yard field goal, but Nugent missed wide left, his first miss in twenty attempts dating back to last season. Boller once again took advantage of the short field provided and hit tight end Todd Heap on a four-yard touchdown with six seconds left in the half to extend the Ravens' lead to 17-3. Heap's catch was initially ruled incomplete, but the call was subjected to a booth review and reversed, as replays showed he was able to touch both feet within the end zone. After a quiet third quarter, Stover hit a 43-yard field goal to start the fourth quarter, and extended Baltimore's lead to seventeen. Baltimore's defense, which ranked as the best in the NFL in 2006, was able to shut down Clemens and the Jets for most of the game, but Clemens was able to rally the team in the fourth quarter. Using a no huddle offense, Clemens drove the team down to the Baltimore three-yard line, before the Jets settled for a 21-yard field goal. On the Jets' next possession, 44 and 24-yard strikes by Clemens to Jerricho Cotchery got the Jets to the Ravens' goal line, where he found tight end Chris Baker for a three-yard touchdown, cutting the Jets' deficit to seven. Though the Jets failed to convert the ensuing onside kick, poor clock management by Boller gave the Jets the ball back with 2:38 left in the game. Clemens immediately found Cotchery on a 50-yard catch-and-run, later followed by a 24-yard pass to Laveranues Coles that brought the Jets' to the Baltimore seven-yard line with just over a minute to go. Clemens passed to Justin McCareins for a potential touchdown, but the pass was dropped by McCareins. A second pass to McCareins in the end zone deflected off him and into the arms of Ravens linebacker Ray Lewis for the game-ending interception. The loss made the Jets 8-20 since 2002 in games not started by Chad Pennington. 
 Question: Who threw the first touchdown pass of the game?
Output: kyle boller
Context: William Henry Christman (October 1,1843 -- May 11, 1864) was the first soldier to be buried in Arlington National Cemetery. 
 Question: In which cemetary is William Henry Christman buried?
Output: arlington national cemetery
Context: Clinical features variability between familial and sporadic restless legs syndrome/Willis-Ekbom disease (RLS/WED) has been previously reported. With this retrospective cohort study, we aimed to determine the clinical and polysomnographic characteristics of 400 RLS/WED patients. Patients with familial RLS/WED were significantly younger than sporadic RLS/WED, while clinical and polysomnographic characteristics were similar in both groups. No difference was found for the age-at-onset between idiopathic and secondary RLS/WED. Periodic limb movements (PLM) index and REM sleep time were higher in idiopathic RLS/WED. Time of onset of symptoms was in the evening or at bedtime in 28.04 and 37.80% of patients, respectively, while in 21.34% of patients onset was more than 1 h after sleep onset. Impulse control and compulsive behaviours (ICBs) were found in 13.29% patients on dopamine agonist therapy. Our analyses support the hypothesis that patients with a familial history of RLS/WED may have a genetic component. Nevertheless, the dichotomy between early and late onset disease seems to be less sharp than previously reported. A large proportion of RLS/WED patients can have atypical features, therefore making the diagnosis challenging. Some cases can be missed even when the patient refers to a sleep specialist, as revealed by the partial absence of daytime symptoms, the high comorbidity with insomnia and other sleep complaints and the high percentage of symptoms beginning after sleep onset. This draws attention on the importance of a careful evaluation of the patient, to recognize potentially treatable secondary forms of RLS/WED. 
 Question: Willis-Ekbom disease is also known as?
Output: restless legs syndrome
Context: Princess Hildegard of Bavaria (German: Hildegard Luise Charlotte Theresia Friederike von Bayern; 10 June 1825 -- 2 April 1864) was the seventh child and fourth daughter of Ludwig I of Bavaria and Therese of Saxe-Hildburghausen. 
 Question: Who was the mother of Princess Hildegard of Bavaria?
Output: therese of saxe-hildburghausen
Context: Elias Hasket Derby (August 16, 1739 -- September 8, 1799) was among the wealthiest and most celebrated of post-Revolutionary merchants in Salem, Massachusetts, and owner of the Grand Turk, the first New England vessel to trade directly with China. 
 Question: What city was Elias Hasket Derby born in?
Output: salem
Context: We investigated the validity of probe-to-bone testing in the diagnosis of osteomyelitis in a selected subgroup of patients clinically suspected of having diabetic foot osteomyelitis. Between January 1, 2007, and December 31, 2008, inpatients and outpatients with a diabetic foot ulcer were prospectively evaluated, and those having a clinical diagnosis of foot infection and at least one of the osteomyelitis clinical suspicion criteria were consecutively included in this study. Sixty-five patients met the inclusion criteria and were prospectively enrolled in the study. Forty-nine patients (75.4%) were hospitalized, and the remaining 16 (24.6%) were followed as outpatients. Osteomyelitis was diagnosed in 39 patients (60.0%). Probe-to-bone test results were positive in 30 patients (46.1%). The positive predictive value for the probe-to-bone test was fairly high (87%), but the negative predictive value was only 62%. The sensitivity and specificity of the test were 66% and 84%, respectively. White blood cell counts and mean C-reactive protein levels did not statistically significantly differ between groups. However, erythrocyte sedimentation rates greater than 70 mm/h reached statistical significance between groups. Wound area and depth were not found to be statistically significantly different between groups. Positive probe-to-bone test results and erythrocyte sedimentation rates greater than 70 mm/h provide some support for the diagnosis of diabetic foot osteomyelitis, but it is not strong; magnetic resonance imaging or bone biopsy will probably be required in cases of doubt. 
 Question: Which disease can be diagnosed with the "probe to bone" test?
Output: diabetic foot osteomyelitis
Context: When you look at the prickly cactus pictured below ( Figure 1.1), does the word "ouch" come to mind? Touching the cactus would be painful. Touch is the sense of pain, pressure, or temperature. Touch depends on sensory neurons, or nerve cells, in the skin. The skin on the palms of the hands, soles of the feet, and face has the most sensory neurons and is especially sensitive to touch. The tongue and lips are very sensitive to touch as well. Neurons that sense pain are also found inside the body in muscles, joints, and organs. If you have a stomach ache or pain from a sprained ankle, its because of these sensory neurons found inside of your body. The following example shows how messages about touch travel from sensory neurons to the brain, as well as how the brain responds to the messages. Suppose you wanted to test the temperature of the water in a lake before jumping in. You might stick one bare foot in the water. Neurons in the skin on your foot would sense the temperature of the water and send a message about it to your central nervous system. The frontal lobe of the cerebrum would process the information. It might decide that the water is really cold and send a message to your muscles to pull your foot out of the water. In some cases, messages about pain or temperature dont travel all the way to and from the brain. Instead, they travel only as far as the spinal cord, and the spinal cord responds to the messages by giving orders to the muscles. This allows you to respond to pain more quickly. When messages avoid the brain in this way, it forms a reflex arc, like the one shown below ( Figure 1.2). Our sense of touch is controlled by a huge network of nerve endings and touch receptors. This system is responsible for all the sensations we feel, including cold, hot, smooth, rough, pressure, tickle, itch, pain, vibrations, and more. There are four main types of receptors: mechanoreceptors, thermoreceptors, pain receptors, and proprioceptors. Mechanoreceptors perceive sensations such as pressure, vibrations, and texture. Your brain gets an enormous amount of information about the texture of objects through your fingertips because the ridges that make up your fingerprints are full of these sensitive receptors. Thermoreceptors perceive sensations related to the temperature of objects. There are two basic categories of thermoreceptors: hot receptors and cold receptors. The highest concentration of thermoreceptors can be found in the face and ears. Pain receptors, or nociceptor detect pain or stimuli that can or does cause damage to the skin and other tissues of the body. There are over three million pain receptors throughout the body, found in skin, muscles, bones, blood vessels, and some organs. Proprioceptors detect the position of different parts of the body in relation to each other and the surrounding environment. These receptors are found in joints, tendons and muscles, and allow us to do fundamental things such as feeding or clothing ourselves. 
 Question: which receptors perceive sensations such as pressure, vibrations, and texture?
Output: mechanoreceptors
Context: Sir Balan le Savage, brother of Sir Balin from Northumberland, is a minor character mentioned in various Arthurian legends. 
 Question: Who was the brother of Sir Balan?
Output: sir balin
Context: Penobscot tribal chiefs expressed a willingness to enter peace talks with Lieutenant Governor Dummer in December 1724. They were opposed in this by French authorities, who continued to encourage the conflict, but Massachusetts Lieutenant Governor Dummer announced a cessation of hostilities on 31 July 1725 following negotiations in March.:83 The terms of this preliminary agreement were negotiated by Dummer and Chiefs Loron and Wenemouet and applied only to the Penobscots at first. They were allowed to retain Jesuit priests, but the two parties were in disagreement concerning land titles and British sovereignty over the Wabanakis. The written agreement was translated into Abenaki by French Jesuit Etienne Lauverjat; Chief Loron immediately repudiated it, specifically rejecting claims of British sovereignty over him. Despite his disagreement, Loron pursued peace, sending wampum belts to other tribal leaders, although his envoys were unsuccessful in reaching Gray Lock, who continued his raiding expeditions. Peace treaties were signed in Maine on 15 December 1725 and in Nova Scotia on 15 June 1726, involving a large number of tribal chiefs. The peace was reconfirmed by all except Gray Lock at a major gathering at Falmouth in the summer of 1727; other tribal envoys claimed that they were not able to locate him. Gray Lock's activity came to an end in 1727, after which time he disappears from English records. 
 Question: What happened second: announced a cessation of hostilities or peace treaties were signed?
Output: peace treaties were signed
Context: Francesca Morvillo then met Giovanni Falcone, at that time investigating judge in the court of Palermo. 
 Question: What is Francesca Morvillo's spouse's name?
Output: giovanni falcone
Context: Alpha-synuclein is believed to play an important role in Parkinson's disease (PD). Mutations in the alpha-synuclein gene are responsible for familial forms of PD and alpha-synuclein protein is a major component of Lewy bodies in patients with sporadic PD. Synphilin-1 is a novel protein that we have previously found to associate in vivo with alpha-synuclein. We now show that synphilin-1 is present in Lewy bodies of patients with PD. Our data suggest that synphilin-1 could play a role in Lewy body formation and the pathogenesis of PD. 
 Question: Which is the primary protein component of Lewy bodies?
Output: αsyn
Context: Alpha-synuclein is believed to play an important role in Parkinson's disease (PD). Mutations in the alpha-synuclein gene are responsible for familial forms of PD and alpha-synuclein protein is a major component of Lewy bodies in patients with sporadic PD. Synphilin-1 is a novel protein that we have previously found to associate in vivo with alpha-synuclein. We now show that synphilin-1 is present in Lewy bodies of patients with PD. Our data suggest that synphilin-1 could play a role in Lewy body formation and the pathogenesis of PD. 
 Question: Which is the primary protein component of Lewy bodies?
Output: α-synuclein
Context: Alpha-synuclein is believed to play an important role in Parkinson's disease (PD). Mutations in the alpha-synuclein gene are responsible for familial forms of PD and alpha-synuclein protein is a major component of Lewy bodies in patients with sporadic PD. Synphilin-1 is a novel protein that we have previously found to associate in vivo with alpha-synuclein. We now show that synphilin-1 is present in Lewy bodies of patients with PD. Our data suggest that synphilin-1 could play a role in Lewy body formation and the pathogenesis of PD. 
 Question: Which is the primary protein component of Lewy bodies?
Output: alpha-synuclein
Context: The film is a comedy of middle-class French life ' examining culture clashes, puncturing smugness, exposing fault lines, finding strength in romantic and familial relationships and discovering an underlying sadness that stops some way short of tragedy.'[3] The film is set in a small town in Provence during a rainy August. Following the death of her widowed mother Agathe Villanova comes from Paris to deal with the sale of the home where she and her younger sister Florence were brought up, and to announce her entry into politics. She is the author of a feminist best-seller and a divorced film-maker Michel wants to make a TV documentary about her. Michel is having an affair with Agathe's sister. His collaborator is a young Algerian hotel clerk Karim, whose elderly mother has worked for most of her life as a servant with the Villanova family. Agathe's prejudice is put under the microscope when she records a series of interviews with Karim. 'The characters weave around each other for a week or so, occasionally colliding...everyone comes to have a better knowledge of themselves..the dialogue rings true..the ensemble acting is perfect..The film compares favourably with the best of Eric Rohmer.' [4] 
 Question: What is the name of the housekeeper who came to France with Villanova family when they left Algeria?
Output: agathe
Context: ''In the Hands of the Prophets'' is the twentieth and final episode of the first season of the American science fiction television series Star Trek: Deep Space Nine. 
 Question: Which series is In the Hands of the Prophets apart of?
Output: star trek: deep space nine
Context: Perfect Dark was first released in North America on 22 May 2000; 
 Question: Who was the publisher of Perfect Dark?
Output: north america
Context: Seven women in three generations of a family have been affected by Turner syndrome. Turner phenotype in this family is the result of deletion of the entire short arm of one X chromosome. The short arm deletion is transmitted by carriers of a balanced X-1 translocation. Autoradiographic findings showed that the deleted X chromosome was late labeling in those persons with Turner syndrome, whereas the normal X chromosome was late replicating in carriers of the balanced translocation. The results of Xga typing of erythrocytes suggest that the Xg locus is on the short arm of the X chromosome. Because of the clinical implications, we believe that families of persons with structural chromosomal abnormalities should be studied to exclude familial transmission. 
 Question: What chromosome is affected in Turner's syndrome?
Output: x
Context: Kanalaattam is a 1979 Indian Malayalam film, directed by C Radhakrishnan and produced by PMK Bapu. 
 Question: In what year is the film Kanalaattam released?
Output: 1979
Context: Eddie Shu (ne Edward Shulman; 18 March 1918 New York City -- 4 July 1986 St. Petersburg, Florida, though he lived in Tampa) was an American swing and jazz multi-instrumentalist with high proficiency on tenor and alto saxophone, clarinet, trumpet, harmonica, and accordion. 
 Question: At what location did Eddie Shu die?
Output: tampa
Context: Rhopalizus is a genus of round-necked longhorn beetles of the subfamily Cerambycinae. 
 Question: Is Rhopalizus a genus or species?
Output: genus
Context: In Europe, before the outbreak of the war, the Allies had significant advantages in both population and economics. In 1938, the Western Allies had a 30 per cent larger population and a 30 per cent higher gross domestic product than the European Axis powers ; if colonies are included, it then gives the Allies more than a 5:1 advantage in population and nearly 2:1 advantage in GDP. In Asia at the same time, China had roughly six times the population of Japan, but only an 89 per cent higher GDP; this is reduced to three times the population and only a 38 per cent higher GDP if Japanese colonies are included. The United States provided about two-thirds of all the ordnance used by the Allies in terms of warships, transports, warplanes, artillery, tanks, trucks, and ammunition. Though the Allies' economic and population advantages were largely mitigated during the initial rapid blitzkrieg attacks of Germany and Japan, they became the decisive factor by 1942, after the United States and Soviet Union joined the Allies, as the war largely settled into one of attrition. While the Allies' ability to out-produce the Axis is often attributed to the Allies having more access to natural resources, other factors, such as Germany and Japan's reluctance to employ women in the labour force, Allied strategic bombing, and Germany's late shift to a war economy contributed significantly. Additionally, neither Germany nor Japan planned to fight a protracted war, and were not equipped to do so. To improve their production, Germany and Japan used millions of slave labourers; Germany used about 12 million people, mostly from Eastern Europe, while Japan used more than 18 million people in Far East Asia. 
 Question: Who was set up to fight a protracted war?
Output: allies
Context: Paretroplus polyactis is a vulnerable species of cichlid found widely in fresh and brackish water in coastal regions and associated river basins in eastern Madagascar. 
 Question: How endangered does the iucn consider Paretroplus polyactis?
Output: vulnerable
Context: The Steelers' ninth game was an AFC duel with the Patriots. The Steelers trailed early as QB Tom Brady made a 19-yard TD pass to TE Rob Gronkowski. This was followed by kicker Shayne Graham getting a 31-yard field goal. The Steelers responded in the second quarter with kicker Jeff Reed nailing a 22-yard field goal. The Steelers struggled further when Brady threw another TD pass to Gronkowski, this one from 9yards out. That was followed by Brady's scramble 3yards to the endzone for a touchdown (With a failed PAT as the kick went wide-right). The Steelers scored first in the 4th quarter when QB Ben Roethlisberger completed a 6-yard TD pass to WR Emmanuel Sanders. The Steelers looked to create another scoring drive, but it came to a halt when Roethlisberger's pass was intercepted by SS James Sanders and returned 32yards for a touchdown (With a failed 2-point conversion). The Steelers tried to cut the lead with a Roethlisberger 15-yard TD pass to WR Mike Wallace, but the Patriots replied with Brady getting a 25-yard TD pass to Gronkowski. Again the Steelers tried to get closer when Roethlisberger completed a 33-yard TD pass to Wallace, but the Patriots put the game away after Graham hit a 36-yard field goal. 
 Question: Which team scored first in the game?
Output: patriots
Context: Fingolfin (IPA: (fiolfin)) is a fictional character in J. R. R. Tolkien's legendarium, appearing in The Silmarillion. 
 Question: With which fictional universe is the character Fingolfin associated?
Output: tolkien's legendarium
Context: Mad Vallis is a valley in the Hellas quadrangle of Mars, with its location centered at 56.5 S and 283.9 W. It is 524 km long and was named after the Mad River in Vermont, USA. 
 Question: On what moon or planet can Mad Vallis be found?
Output: mars
Context: It seems that beauty and women are twins.You are joking? No,I do not.Observe for yourself Ads on fashion TV screens,radio programs,magazines,newspapers,and the streets.Whether they have realized it or not, women are surrounded by a sea of fashion.They are taught to think that without beautiful clothes they will grow old and lose their charm.So who dares to neglect dressing up at the cost of their appearance and youth? But I do not agree with the opinion that women have to show their beauty through their looks.The richness of their minds proves to be more beautiful and attractive than their looks.A woman who has experienced many troubles and may be called "aunt" or "granny" can still keep up her beauty if she has such excellent qualities as knowledge,ability,a kind heart,great courage,concern for others,etc. In addition,old and young,beautiful and ugly are concept.People who keep a young mind will never feel old.Interested in new things and eager to learn more,they keep up with the tide.Plainly dressed women may have a type of beauty that is pure and real.Reading and learning is the best way to keep one youthful.Good books ale rich soil which can feed the flower of one's heart and looks. 
 Question: What is the best way for a woman to appear young according to the writer?
Output: reading and learning.
Context: Todo Noticias (also known as TN) is an Argentine news cable channel. 
 Question: Which industry is Todo Noticias associated with?
Output: news
Context: Tabish Khair (Hindi: ) is an Indian English author and associate professor in the Department of English, University of Aarhus in Denmark. 
 Question: What was Tabish Khair's nationality?
Output: english
Context: Machado-Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), may be the most common dominantly inherited ataxia in the world. Here I will review historical, clinical, neuropathological, genetic, and pathogenic features of MJD, and finish with a brief discussion of present, and possible future, treatment for this currently incurable disorder. Like many other dominantly inherited ataxias, MJD/SCA3 shows remarkable clinical heterogeneity, reflecting the underlying genetic defect: an unstable CAG trinucleotide repeat that varies in size among affected persons. This pathogenic repeat in MJD/SCA3 encodes an expanded tract of the amino acid glutamine in the disease protein, which is known as ataxin-3. MJD/SCA3 is one of nine identified polyglutamine neurodegenerative diseases which share features of pathogenesis centered on protein misfolding and accumulation. The specific properties of MJD/SCA3 and its disease protein are discussed in light of what is known about the entire class of polyglutamine diseases. 
 Question: Which is the protein implicated in Spinocerebellar ataxia type 3?
Output: ataxin-3
Context: Ron Bozman is an American film producer who won an Academy Award for Best Picture in 1991 for the film The Silence of the Lambs. 
 Question: What was Ron Bozman nominated for?
Output: academy award for best picture
Context: Yoann de Boer (born 27 January 1982) is a French professional footballer who plays as a defensive midfielder for Kozakken Boys in the Dutch Topklasse. 
 Question: What role does Yoann de Boer play in football?
Output: midfielder
Context: Nuclear-powered aircraft carriers are considered one of the most important marine weapons in the 20th century. So far, only two countries in the world--the prefix = st1 /USAandFrance--have ever produced them. But these frightful fighting machines are about to enter Asia. The US Navy said last month that one of its nine nuclear-powered aircraft carriers will be sent to Japanto replace the diesel-powered carrier Kitty Hawk in 2009 in an agreement on October 30th. The two countries also planned to level up their military cooperation and theUSAcalled forJapanto take a large role in alliance military moves. It will be the first time that a nuclear-powered carrier is based in Japan. Bombed byUSforces in World War II at Hiroshima and Nagasaki,Japanis the only world country to have been attacked by a nuclear weapon. Therefore, the citizens are highly sensitive to where nuclear-powered weapons are based. "A radiation leak at Yokosuka would kill 100,000 people as far away as Tokyo, and could cause billions of dollars in damage," said Masahiko Go to, leader of a protest group inYokosuka. His group has collected more than 300,000 signatures of people acrossJapanopposed to the nuclear carrier. The 44-year-old Kitty Hawk, the USnavy's oldest active ship, has been based in Yokosuda since 1998. The new carrier, yet to be _ , will travel faster, be capable of supporting longer operations and carry with it the Navy's most modern technology. Experts pointed that this change is not only to strengthen the US-Japan military alliance but also to keep the military power of ChinaandNorth Koreawithin limits. However, Japanese experts don't believe that the countries are threats to the region. "There is no need for Japanto have a nuclear carrier as defense," said Tetsuo Maeda, an international relations professor atTokyoInternationalUniversity. He said that the change of ship indicates an increased military capacity, in the region, much more than what is needed. 
 Question: The replacement of the aircraft carrier is intended to
Output: strengthen the us-japan military alliance
Context: 162 Laurentia is a large and dark main-belt asteroid that was discovered by the French brothers Paul Henry and Prosper Henry on April 21, 1876, and named after A. Laurent, an amateur astronomer who discovered asteroid 51 Nemausa. 
 Question: Whom is 162 Laurentia named after?
Output: a. laurent
Context: Bianchi cavalli d'Agosto (internationally known as White Horses of Summer) is a 1975 Italian drama film written and directed by Raimondo Del Balzo. 
 Question: Who served as director for White Horses of Summer?
Output: raimondo del balzo
Context: The AJK Jaguars (Urdu: ) are a Pakistani men's professional Twenty20 cricket team that competes in the Haier T20 League and based in Mirpur, Azad Jammu and Kashmir, Pakistan. 
 Question: Which sport has connection with AJK Jaguars?
Output: cricket
Context: Imatinib mesylate is a new drug that can inhibit the tyrosine kinase activity of Bcr-Abl, the receptors for platelet-derived growth factor receptor(PDGF) and stem cell factor, or c-kit. Chronic myeloid leukemia (CML) is distinguished by the presence of a reciprocal translocation between chromosomes 9 and 22 that results in a shortened chromosome 22, termed the Philadelphia(Ph) chromosome. As a result of the translocation, a fusion gene called the Bcr-Abl gene is created from two normal cellular genes, encoding a chimeric Bcr-Abl protein with a deregulated tyrosine kinase activity. The expression of Bcr-Abl tyrosine kinase has been shown to be necessary and sufficient for the transformed phenotype of CML cells. Imatinib can block the kinase activity of Bcr-Abl, thus inhibiting the proliferation of Ph-positive progenitors, and has shown activity against all phases of CML, though responses are most substantial and durable in patients in the chronic phase. An international phase III study which compared the efficacy of imatinib with that of interferon alpha combined with low-dose cytarabine in newly diagnosed chronic-phase CML showed the rate of major cytogenetic response at 24 months was 90%, including 82% of complete cytogenetic response. These results indicated that imatinib was superior to interferon-containing treatment as a first-line therapy. More than 10,000 patients worldwide, including those in Japan, have been treated with imatinib in clinical trials, and a lot of information has been accumulated on the use of this drug. The aim of this article is to review the use of this drug and the practical management of patients with chronic myeloid leukemia. 
 Question: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?
Output: bcr-abl
Context: The most important use of drifting bottles is to find ocean currents. When the position and direction of currents are known, ships can use the forward movement of a current or stay away from currents that would carry them off their course. Benjamin Franklin was one of the first to use bottles in the study of currents. He wondered why British mall ships needed a week or two longer than U.S. ships needed in order to cross the Atlantic Ocean. Franklin thought the Gulf Stream might explain this difference. Franklin talked with captains of U.S. ships. He found that they knew each turn of the Gulf Stream. They used the current in every possible way. From his talks with the captains. Franklin made his first map of the Gulf Stream. Then he checked his map by using sealed bottles. The map that he finally made is still used, with only a few changes, today. 
 Question: What did Franklin make after his talks with U.S. captains?
Output: a map of the gulf stream..
Context: As of the census of 2000, there were 445,342 people, 169,162 households, and 114,015 families residing in the county. The population density was 615 people per square mile (238/km). There were 178,913 housing units at an average density of 247 per square mile (95/km). The racial makeup of the county was 82.19% Race (United States Census), 1.15% Race (United States Census) or Race (United States Census), 0.65% Race (United States Census), 6.68% Race (United States Census), 0.30% Race (United States Census), 5.86% from Race (United States Census), and 3.17% from two or more races. 11.17% of the population were Race (United States Census) or Race (United States Census) of any race. 17.2% were of German American, 9.9% English American, 8.2% Irish American, and 6.7% Americans ancestry. 81.7% spoke only English at home, while 9.6% spoke Spanish and 1.2% Vietnamese. 
 Question: Which group from the census in the county is smaller: English American or Americans ancestry?
Output: americans ancestry
Context: The Raiders traveled across the bay to Monster Park in San Francisco to take on the 49ers. The 49ers got on the board first with an Alex Smith to Arnaz Battle touchdown pass midway through the first quarter. The Raiders responded with a 33-yard field goal by Sebastian Janikowski. Janikowski then converted a 36 yarder early in the second quarter. Randy Moss scored his 100th career touchdown reception on a 22-yard pass from Andrew Walter, as the Raiders went into halftime with a 13-7 lead. The 49ers then went on to score 24 unanswered points in the second half, as Smith connected on touchdown passes with Battle once again, and Maurice Hicks in the third quarter. Joe Nedney converted a chip shot 19-yard field goal early in the fourth quarter. On the next Raiders play from scrimmage, Melvin Oliver recovered a fumble for a touchdown, as Walter tried to lateral a pass to LaMont Jordan, who let it hit the ground, and assumed it was an incomplete pass. Marques Tuiasosopo hit Courtney Anderson with a touchdown pass late in the game, but it was too little too late. Nedney completed the scoring with a 39-yard field goal. 
 Question: How many yards was the final move of the game?
Output: 39-yard
Context: Sir Wilfred Robarts, a famed barrister, has just been released from the hospital in which he stayed for two months following a heart attack. Returning to his practise of law, he takes the case of Leonard Vole, an unemployed man who is accused of murdering his elderly friend, Mrs. Emily French. Vole claims he's innocent, although all evidence points to him as the killer, but his alibi witness, his cold German wife Christine, instead of entering the court as a witness for the defense, becomes the witness for the prosecution and defiantly testifies that her husband is guilty of the murder. Sir Wilfred believes there's something suspicious going on with the case, particularly with Mrs. Vole. 
 Question: What is Sir Wilfred Robert's profession?
Output: barrister