niryuu/sni-each-converted huggingface dataset:
Context: The U.S. Census for 2010 reported 332,199 households in Indianapolis, with an average household size of 2.42 and an average family size of 3.08. Of the total households, 59.3% were family households, with 28.2% of these including the familys own children under the age of 18; 36.5% were husband-wife families; 17.2% had a female householder (with no husband present) and 5.6% had a male householder (with no wife present). The remaining 40.7% were non-family households. , 32% of the non-family households included individuals living alone, 8.3% of these households included individuals age 65 years of age or older. 
 Question: which household was least common?
Output: male householder
Context: On July 15, 2009 Nucleosys was announced to be disbanding. 
 Question: What year was the end of Nucleosys?
Output: 2009
Context: XMission is the first and is one of the few remaining independent Internet Service Providers (ISP) in Utah, United States, founded in late 1993 by Pete Ashdown. 
 Question: Who is the founder of XMission?
Output: pete ashdown
Context: Rocks deforming plastically under compressive stresses crumple into folds. They do not return to their original shape. If the rocks experience more stress, they may undergo more folding or even fracture. You can see three types of folds. A monocline is a simple bend in the rock layers so that they are no longer horizontal (see Figure 1.1 for an example). At Utahs Cockscomb, the rocks plunge downward in a monocline. What you see in the image appears to be a monocline. Are you certain it is a monocline? What else might it be? What would you have to do to figure it out? Anticline: An anticline is a fold that arches upward. The rocks dip away from the center of the fold (Figure 1.2). The oldest rocks are at the center of an anticline and the youngest are draped over them. When rocks arch upward to form a circular structure, that structure is called a dome. If the top of the dome is sliced off, where are the oldest rocks located? A syncline is a fold that bends downward. The youngest rocks are at the center and the oldest are at the outside (Figure 1.3). When rocks bend downward in a circular structure, that structure is called a basin (Figure 1.4). If the rocks are exposed at the surface, where are the oldest rocks located? Click image to the left or use the URL below. URL: Anticlines are formations that have folded rocks upward. (a) Schematic of a syncline. (b) This syncline is in Rainbow Basin, California. Some folding can be fairly complicated. What do you see in the photo above? 
 Question: rocks that deform plastically under compressive stresses crumple into this.
Output: folds
Context: The RTS,S/AS01(E) malaria candidate vaccine is being developed for immunization of African infants through the Expanded Program of Immunization (EPI). This phase 2, randomized, open, controlled trial conducted in Ghana, Tanzania, and Gabon evaluated the safety and immunogenicity of RTS,S/AS01(E) when coadministered with EPI vaccines. Five hundred eleven infants were randomized to receive RTS,S/AS01(E) at 0, 1, and 2 months (in 3 doses with diphtheria, tetanus, and whole-cell pertussis conjugate [DTPw]; hepatitis B [HepB]; Haemophilus influenzae type b [Hib]; and oral polio vaccine [OPV]), RTS,S/AS01(E) at 0, 1, and 7 months (2 doses with DTPwHepB/Hib+OPV and 1 dose with measles and yellow fever), or EPI vaccines only. The occurrences of serious adverse events were balanced across groups; none were vaccine-related. One child from the control group died. Mild to moderate fever and diaper dermatitis occurred more frequently in the RTS,S/AS01(E) coadministration groups. RTS,S/AS01(E) generated high anti-circumsporozoite protein and anti-hepatitis B surface antigen antibody levels. Regarding EPI vaccine responses upon coadministration when considering both immunization schedules, despite a tendency toward lower geometric mean titers to some EPI antigens, predefined noninferiority criteria were met for all EPI antigens except for polio 3 when EPI vaccines were given with RTS,S/AS01(E) at 0, 1, and 2 months. However, when antibody levels at screening were taken into account, the rates of response to polio 3 antigens were comparable between groups. RTS,S/AS01(E) integrated in the EPI showed a favorable safety and immunogenicity evaluation. Trial registration. ClinicalTrials.gov identifier: NCT00436007 . GlaxoSmithKline study ID number: 106369 (Malaria-050). 
 Question: RTS S AS01 vaccine was developed to prevent which disease?
Output: malaria
Context: CADASIL is the most prominent inherited form of vascular dementia. The main clinical features include migraine with aura, stroke, mood disturbances, and cognitive decline, with a mid-life (30s-60s) adult onset. Genetic testing is the gold standard for the diagnosis. CADASIL is caused mostly by missense mutations in the NOTCH3 gene, invariably involving a cysteine residue. Only a couple of splice site mutations have been reported. In a few pathologically defined patients, genetic mutations remain unidentified. We report a family with late-onset CADASIL phenotype carrying a novel intronic deletion in the NOTCH3 gene (c.341-26_24delAAC). Transcript analysis revealed a splicing alteration, with the complete intron 3 retention. The insertion was in-frame and encoded an extra 25 amino acids, including 1 cysteine. This is the first report of an aberrant splicing event of the NOTCH3 gene associated with a mutation far away from the canonical splice site. Our finding suggests that the assays used to evaluate splicing should be mandatory in the diagnostic setting of genetically undefined CADASIL cases. 
 Question: Which amino acid residue appears mutated in most of the cases reported with cadasil syndrome?
Output: cysteine
Context: The eukaryotic cell encounters more than one million various kinds of DNA lesions per day. The nucleotide excision repair (NER) pathway is one of the most important repair mechanisms that removes a wide spectrum of different DNA lesions. NER operates through two sub pathways: global genome repair (GGR) and transcription-coupled repair (TCR). GGR repairs the DNA damage throughout the entire genome and is initiated by the HR23B/XPC complex, while the CSB protein-governed TCR process removes DNA lesions from the actively transcribed strand. The sequence of events and the role of particular NER proteins are currently being extensively discussed. NER proteins also participate in other cellular processes like replication, transcription, chromatin maintenance and protein turnover. Defects in NER underlay severe genetic disorders: xeroderma pigmentosum (XP), Cockayne syndrome (CS) and trichothiodystrophy (TTD). 
 Question: Which gene strand is targeted by transcription-coupled repair (TCR)?
Output: the transcribed strand
Context: Lesla-Lar is a fictional character, a supervillain in the DC Universe. 
 Question: What is the fictional universe that Lesla-Lar belong to?
Output: dc universe
Context: Georgios Papoulias died from an apparent suicide on September 11, 2009, at the age of 82, following serious health problems. 
 Question: In one word, how did Georgios Papoulias die?
Output: suicide
Context: Notre-Dame du Reclus Abbey or Sancta Maria de Recluso Abbey was a male Cistercian monastery near Sezanne in the Epernay arrondissement of the diocese of Troyes. 
 Question: What group was Notre-Dame du Reclus Abbey a member of?
Output: cistercian
Context: +'Justments is a 1974 album by Bill Withers, released by Sussex Records. 
 Question: Which was the record label for +'Justments?
Output: sussex records
Context: Aviateca Flight 901 was a Boeing 737-200 (registration N125GU) that crashed into the San Vicente volcano in El Salvador on approach to the airport on 9 August 1995. 
 Question: What is the full date that Aviateca Flight 901 crashed on?
Output: 9 august 1995
Context: At the dedication ceremony the Secretary of State said the following words about him: ''One voice that should have spoken here today is silent, but many of us cannot forget or cease to mourn and to honor our dear and noble friend, Joaquim Nabuco. Ambassador from Brazil, dean of the American diplomatic corps, respected, admired, trusted, loved and followed by all of us, he was a commanding figure in the international movement of which the creation of this building is part...'' (Citation: Ronald Hilton and Alexander Wyse, Reviewed Work: '''The Life of Joaquim Nabuco'' by Carolina Nabuco' in the journal of The Americas, 1950.) 
 Question: What was Joaquim Nabuco's child's name?
Output: carolina nabuco
Context: People depend on natural resources for just about everything that keeps us fed and sheltered, as well as for the things that keep us entertained. Every person in the United States uses about 20,000 kilograms (40,000 pounds) of minerals every year for a wide range of products, such as cell phones, TVs, jewelry, and cars. Table 1.1 shows some common objects, the materials they are made from, and whether they are renewable or non-renewable. Common Object Natural Resources Used Cars 15 different metals, such as iron, lead, and chromium to make the body. Precious metals like gold, silver, and platinum. Gems like diamonds, rubies, emer- alds, turquoise. Jewelry Are These Resources Renewable or Non-Renewable? Non-renewable Non-renewable Common Object Natural Resources Used Electronic Appliances (TVs, com- puters, DVD players, cell phones, etc.) Clothing Many different metals, like copper, mercury, gold. Food Bottled Water Gasoline Household Electricity Paper Houses Soil to grow fibers such as cotton. Sunlight for the plants to grow. Animals for fur and leather. Soil to grow plants. Wildlife and agricultural animals. Water from streams or springs. Petroleum products to make plastic bottles. Petroleum drilled from wells. Coal, natural gas, solar power, wind power, hydroelectric power. Trees; Sunlight Soil. Trees for timber. Rocks and minerals for construc- tion materials, for example, granite, gravel, sand. Are These Resources Renewable or Non-Renewable? Non-renewable Renewable Renewable Non-renewable and Renewable Non-renewable Non-renewable and Renewable Renewable Non-renewable and Renewable Click image to the left or use the URL below. URL: Click image to the left or use the URL below. URL: 
 Question: which common object is made mostly or entirely from renewable resources?
Output: paper
Context: Coming off their bye week, the Jets stayed at home for a Week 10 duel with the Jacksonville Jaguars. New York would trail early in the first quarter with running back Maurice Jones-Drew's 33-yard touchdown run. The Jets would respond with kicker Jay Feely getting a 32-yard field goal, followed by rookie quarterback Mark Sanchez completing a 7-yard touchdown pass to wide receiver Jerricho Cotchery. In the second quarter, Jacksonville would take the lead as quarterback David Garrard got an 11-yard touchdown run and completed a 26-yard touchdown pass to wide receiver Mike Sims-Walker. New York would close out the half as Feely made a 37-yard field goal. After a scoreless third quarter, the Jets would regain the lead in the fourth quarter with a 40-yard field goal from Feely and a 1-yard touchdown run from running back Thomas Jones (with a failed 2-point conversion). However, the Jaguars got the last laugh as kicker Josh Scobee booted the game-winning 21-yard field goal. 
 Question: Who threw the second longest TD pass?
Output: mark sanchez
Context: The Rebellion was the career highlight for both leaders; Cumberland resigned from the Army in 1757 and died of a stroke in 1765. Charles was initially treated as a hero on his return to Paris but the Stuarts were once again barred from France by the 1748 Treaty of Aix-la-Chapelle. Henry Stuart's entry into the Catholic Church in June 1747 was seen as tacit acceptance the Jacobites were finished and Charles never forgave him. He continued attempts to reignite the cause, including a secret visit to London in 1750 but habitual heavy drinking made him argumentative and hard to work with. In 1759, he met French Chief Minister de Choiseul to discuss another invasion attempt but Choiseul dismissed him as incapable through drink. When his father James died in 1766, Pope Clement XIII refused to recognise him as Charles III, despite the strong objections of his brother Henry. Charles never visited Britain again and died in Rome in January 1788, a disappointed and embittered man. 
 Question: Who was Charles' father?
Output: james
Context: A total of about 790,000 tickets were put on sale from February 2015 online, at the Singapore Indoor Stadium and at SingPost outlets. To encourage public participation in the games, it was announced on 28 January 2015 that 18 of the sports will be free for spectators, while the other 18 are kept at relatively affordable levels of between S$5 to S$20. By 15 April 2015 some sports such as swimming and fencing were selling fast, while silat and sepak takraw were much less popular. Organisers reported that ticket sales were pass 70% for most sports by 27 April, with fencing and swimming being the most popular at 85 and 70% tickets sold respectively, while rhythmic gymnastics, silat and wushu have also sold over 70%. Billiards and snooker, equestrian, sepak takraw, taekwondo, and artistic gymnastics have sold about half their tickets. Rugby and judo have sold 30%, while table tennis has sold only 20%. Priced between S$5 to S$20, priority sales for the opening and closing ceremonies tickets for those who registered theirs interests in 2014 began on 15 January 2015, while sales for the general public began on 22 January 2015. In February 2015, tickets to the opening ceremony were going at over seven times their original value on unauthorised websites, despite 40% of the tickets still available at that time. By March 2015, tickets to the opening ceremony were sold out. 
 Question: What was the maximum someone would pay to see a game?
Output: 20
Context: Loss-of-function mutations in the gene ced-8 lead to the late appearance of cell corpses during embryonic development in C. elegans. ced-8 functions downstream of or in parallel to-the regulatory cell death gene ced-9 and may function as a cell death effector downstream of the caspase encoded by the programmed cell death killer gene ced-3. In ced-8 mutants, embryonic programmed cell death probably initiates normally but proceeds slowly. ced-8 encodes a transmembrane protein that appears to be localized to the plasma membrane. The CED-8 protein is similar to human XK, a putative membrane transport protein implicated in McLeod Syndrome, a form of hereditary neuroacanthocytosis. 
 Question: Mutation of which gene is associated with McLeod syndrome?
Output: xk
Context: Leonardo Ghiraldini (born 26 December 1984 in Padua) is an Italian rugby union player for Leicester Tigers in the Aviva Premiership. 
 Question: Which team does Leonardo Ghiraldini play for?
Output: leicester tigers
Context: Viliuisk encephalomyelitis (VE) is an endemic neurological disease in Northeast Siberia and generally considered to be a chronic encephalomyelitis of unknown origin actually spreading in the Sakha (Yakutian) Republic. In search for the pathophysiology and causative agent of VE, we performed a cross-sectional study on clinical, serological and neuroimaging data on chronic VE patients during two medical expeditions to three villages within the Viliuiski river basin in the Republic of Sakha in 2000 and to the capital Yakutsk in 2006. The severity of the core clinical picture with predominant sensory ataxia, gait apraxia, lower limb spasticity, cognitive impairment and bladder dysfunction correlated with the degree of MRI findings showing enlargement of inner ventricular spaces as in communicating hydrocephalus. Laboratory studies revealed transient eosinophilia during the preceding acute meningitis-like phase, but no ongoing inflammatory process in the CSF. We found immune reactions against Toxocara canis in the majority of chronic VE patients but rarely in controls (P = 0.025; Fisher's exact test). Histological analysis of subacute to subchronic VE brain samples showed eosinophilic infiltrations with no signs of persistent Toxocara canis infection. Our data showed that pressure by the communicating hydrocephalus as a mechanical factor is the major pathogenic mechanism in chronic VE, most likely triggered by eosinophilic meningitis. There are no signs for an ongoing inflammatory process in chronic VE. The past eosinophilic reaction in VE might be caused by Toxocara ssp. infection and might therefore represent the first hint for an initial cause leading to the development of chronic VE. Our data provide a framework for future studies and potential therapeutic interventions for this enigmatic epidemic neurological disease potentially spreading in Sakha Republic. 
 Question: Viliuisk encephalomyelitis is diagnosed in which geographical area?
Output: northeast siberia
Context: The police must investigate a series of robberies along a strip of land in the city. The new mayor of the city (Kenneth Mars) assigns Captain Harris (G.W. Bailey) and Lt. Proctor (Lance Kinsey) to the case, but while on stakeout the Wilson gang manages to slip through their fingers.The Mayor wants Harris and Proctor to work with Police Academy head Commandant Lassard (George Gaynes) on apprehending the gang. Lassard assembles a seven-man team consisting of Hightower (Bubba Smith), Tackleberry (David Graf), Jones (Michael Winslow), Hooks (Marion Ramsey), Callahan (Leslie Easterbrook), Fackler (Bruce Mahler), and Lassard's nephew, Nick (Matt McCoy) who transfers from Miami (in the previous film Police Acdemy 5) to the city to remain close to his friends and dull-witted uncle.After distributing flyers as to the information of the Wilson gang and getting nowhere, Nick McCoy stumbles upon a paper heading of an antique diamond heading to a museum, and gets an idea to use it as bait: however the robbers nab the diamond anyway by cutting a hole in the truck and escaping through the sewer system. McCoy then decides to go undercover to get information regarding a possible hideout, but Harris decides to go undercover to get a confession.It turns out that Harris goes undercover as a window washer at a tall building, for which he has a fear of heights, and gets a confession of himself on tape after his loyal but numb-skull lacky, Proctor, accidentally knocks him over the balcony.It is revealed here that the robberies are committed by a group of three dim-witted criminals who do not seem to be able to do this on their own, and it is revealed they are being guided by a literally shadow figure known as the "Mastermind", who speaks to the three behind a wall of glass and uses a voice distortion device. He devises a plan to get the cops out of the way.Commandant Lassard and his men are later suspended after stolen jewellery from the last robbery is planted in Lassard's locker, pending an investigation. The misfit cops decide to clear Lassard's name by nabbing the gang and the ringleader. Accessing data files from a computer, McCoy deduces that the robberies are occurring along a bus route, thus intentionally lowering property values in that part of the city. They also learn that someone must be 'leaking' information to the bad guys, which is why they are always one step ahead of the Police Academy.The Police Academy force finds and does battle with the Wilson gang, while Nick chases the leader. A pursuit follows, which leads to Commissioner Hurst's (George Robertson) office. It is revealed that the Mayor is the "Mastermind" and that Captain Harris has been unwittingly leaking information during his daily meetings with the Mayor. Hurst apologizes and reinstates the force, and a plaque is given to honor the officers' bravery the next day.As the movie closes, Harris is sitting in a chair when a string tying the balloon float is cut, lifting his chair and floating him up into the air as he shouts Proctor's name. 
 Question: What is the name of the gang the police are looking for?
Output: wilson gang
Context: BEIJING - Astronomers have defended against rumors that the terrible earthquake and the following tsunami in Japan were closely related to or even caused by the "supermoon" that will appear in the sky on Saturday. The word "supermoon" was introduced in a report by the British newspaper Daily Mail on March 9, which said amateur scientists were warning that such an astronomical phenomenon could disturb the Earth's climate patterns and may even cause earthquakes and volcanic activity. The moon will be 356,577 kilometers from the Earth on Saturday, the closest in 19 years, and the closest point in its oval orbit coincides with a full moon, the report said. However, Saturday's moon is not actually the closest to Earth in 19 years, Tang Haiming, an astronomer with Shanghai Astronomical Observatory under the Chinese Academy of Sciences, told Xinhua News Agency. A shorter distance of 356,570 km between the two bodies was reached in January 2005, and a distance of 356,566 km was seen in December 2008. Yet some people suggest that previous supermoons have occurred prior to extreme weather events. In 1974 the phenomenon was followed by Cyclone Tracy in Darwin, Australia, and in 2005 it occurred shortly before a deadly tsunami in Indonesia. Coincidentally, two fresh disasters happened in Asia right before Saturday's supermoon. The public's concern about their connection with the moon boomed after Japan's terrible earthquake and tsunami and an earthquake in Southwest China's Yunnan province that killed 25 people on March 10. But astronomers are trying to _ people that such rumors are merely unreasonable. "A supermoon could cause high tides but has no direct relation with natural disasters such as earthquakes," Liu Jie, a researcher with the China Earthquake Network Center, told China Daily on Tuesday. "We can't find any necessary connection between previous supermoons and earthquakes. And the quake in Japan occurred because the Earth's inner energy had accumulated to some extent, and it's not related to the moon. " he said. James Garvin, chief scientist at the Goddard Space Flight Center under NASA, said in an article on NASA's website that "the effects on Earth from a supermoon are minor.""The combination of the moon being at its closest to Earth in its orbit, and being in its 'full moon' configuration ( to the Earth and sun), should not affect the inner energy balance of the Earth, since there are lunar tides every day. " Zhu Jin, curator of the Beijing Planetarium, said"the moon moves around the earth in a certain path, so each orbit has a perigee - its closest approach, and an apogee - its furthest distance.""A lunar perigee occurs once a month and there are very small differences in distances between perigees,"he said."Those tiny differences are far from enough to cause earthquakes or eruption of a volcano,"he added. 
 Question: What's the real reason for the quake in Japan?
Output: because the earth's inner energy had accumulated to some extent.
Context: The objective of this study was to analyze the expression levels of multiple components in the mammalian target of rapamycin (mTOR) signaling pathway in radical nephrectomy specimens from patients with metastatic renal-cell carcinoma (RCC) treated with mTOR inhibitors in order to identify factors predicting susceptibility to these agents. This study retrospectively included a total of 48 consecutive patients undergoing radical nephrectomy, who were diagnosed with metastatic RCC and subsequently treated with an mTOR inhibitor (everolimus or temsirolimus) as either first- or second-line systemic therapy. Expression levels of 5 molecular markers involved in the signaling pathway associated with mTOR, including PTEN, phosphorylated (p)-Akt, p-mTOR, p-p70 ribosomal S6 kinase, and p-4E-binding protein 1 (4E-BP1), were measured by immunohistochemical staining of primary RCC specimens. Of several factors examined, bone metastasis, liver metastasis, and the expression level of p-4E-BP1 were shown to have significant impacts on the response to the mTOR inhibitors. Progression-free survival (PFS) was significantly correlated with the expression levels of PTEN and p-4E-BP1 in addition to the presence of bone metastasis on univariate analysis. Of these significant factors, p-4E-BP1 expression and bone metastasis appeared to be independently associated with PFS on multivariate analysis. These findings suggest that it would be useful to consider the expression levels of potential molecular markers in the mTOR signaling pathway, particularly p-4E-BP1, as well as conventional clinical parameters when selecting patients with metastatic RCC who are likely to benefit from treatment with mTOR inhibitors. 
 Question: What does mTOR stands for?
Output: mammalian target of rapamycin
Context: He was the son of The 4th Earl of Clanricarde by his wife Frances Walsingham. Ulick's father was from an Anglo-Norman family who had been long settled in the west of Ireland and had become Gaelicised. Although during the early sixteenth century the family had rebelled against the Crown on several occasions, Ulick's father had been a strong supporter of Queen Elizabeth I. He fought on the Queen's side during Tyrone's Rebellion, notably during the victory at the Battle of Kinsale, where he was wounded. After the war he married the widow of The 2nd Earl of Essex, a recent commander in Ireland, who was the daughter of the English Secretary of State and spymaster Sir Francis Walsingham. In 1622, Ulick married his only wife Anne Compton, the daughter of The 1st Earl of Northampton and his wife, Elizabeth Spencer. They had a single child, Margaret Burgh, who married Viscount Muskerry. Ulick was summoned to the House of Lords as Lord Burgh in 1628, and succeeded his father as 5th Earl of Clanricarde in 1635. In 1636, he inherited Somerhill House on the death of his father. He was a staunch opponent of the policies of the Lord Deputy of Ireland, The 1st Earl of Strafford, who had attempted to seize much of the great Burke inheritance for the Crown; there was also personal ill-feeling between the two men since the dispute was thought by many to have hastened the death of Ulick's elderly father. He sat in the Short Parliament of 1640 and attended King Charles I in the Scottish expedition. Charles, unlike Strafford, liked and trusted Lord Clanricarde. 
 Question: Who fought on the Queen's side during Tyrone's Rebellion?
Output: ulick's father
Context: Tobacco companies are fighting efforts in the United States and Australia to make their products less appealing. In Washington, a federal judge last week blocked the Food and Drug Administration from requiring new warning labels on cigarette packs. Judge Richard Leon ruled in a case brought by five tobacco companies. The judge temporarily stopped a new federal rule which requires large new warnings starting next September. These include color1 images such as a dead body or diseased lungs. And simple text warnings now appear. Congress called for color1 images showing the dangers of smoking, similar to what Canada does. But the tobacco companies say the new requirements approved in June violate their free speech rights guaranteed by the Constitution. Judge Leon said the FDA could not require the new labels before a lawsuit against the government is decided. Some experts say the process could take years. The judge said he believed the cigarette makers were highly likely to win their case. He said the images should be designed to appeal to emotions, rejecting government arguments that they should be purely factual. He accused the government of trying to use the labels to promote an "obvious anti-smoking agenda?" The head of an anti-smoking group, the Campaign for Tobacco-Free Kids, called the decision "wrong on the science and wrong on the law". About one-fifth of American adults smoke. The World Health Organization says tobacco kills nearly six mil-lion people worldwide each year. More than six hundred thousand of them are non-smokers who breathe other people's tobacco smoke. In Australia, tobacco companies want to stop what would be the world's most restrictive laws on cigarette advertising. Cigarettes could be sold only in plain olive-green packages. Only the brand name and health warnings could appear. The Senate passed the bill last week and sent it back to the Lower House to approve minor amendments . The law is to go into effect in December of next year. Tobacco companies Say the legislation violates the Australian constitution. They say it would unjustly reduce the value of their brand names and trademarks. Health Minister Nicola Roxon says the government is ready for a legal fight. 
 Question: Which country has adopted color1 images showing the dangers of smoking as warning labels?
Output: canada.
Context: Methylphenidate was first synthesized in 1944, and was identified as a stimulant in 1954. 
 Question: What is the full date of discovery for Methylphenidate?
Output: 1944
Context: Playing in their second game of the season, the Cincinnati Bengals had a lot of things go wrong. Playing Ohio state rivals Cleveland Browns, the defense looked the exact opposite as they did in week one. Browns quarterback Derek Anderson started and threw for 328 yards and five touchdowns. It was only the third time in NFL history that two quarterbacks had thrown at least five touchdown passes in the same game. Jamal Lewis had 215 yards rushing with one touchdown and the Browns had two receivers with over 100 yards, Braylon Edwards and Kellen Winslow. The Bengals offense tried their best to keep the team in the game, however, as Carson Palmer threw for 6 TD's and Chad Johnson caught for 209 yards. The game started out slowly in the first quarter but the second quarter saw a combined 35 points scored. It was close in the end, when the Bengals started a drive with under one minute left. They managed to get the ball to the 50-yard line when Carson Palmer was intercepted by Leigh Bodden on an intended pass for Chad Johnson. This game ended up being the eighth highest scoring game in NFL history, but not the highest scoring game between these two teams. In 2004, the Bengals beat the Browns 58-48 for the second-most combined points. The Redskins (72) and Giants (41) combined for 113 points in 1966 for the most. Q1 - CIN - 10:40 - 13-yard TD pass from Carson Palmer to Rudi Johnson (Shayne Graham kick) (CIN 7-0) Q1 - CLE - 5:02 - Phil Dawson 39-yard FG (CIN 7-3) Q1 - CLE - 0:09 - Phil Dawson 39-yard FG (CIN 7-6) Q2 - CLE - 11:02 - 17-yard TD pass from Derek Anderson to Joe Jurevicius (Dawson kick) (CLE 13-7) Q2 - CIN - 7:40 - 23-yard TD pass from Carson Palmer to T. J. Houshmandzadeh (Graham kick) (CIN 14-13) Q2 - CLE - 6:37 - 9-yard TD pass from Derek Anderson to Joe Jurevicius (Dawson kick) (CLE 20-14) Q2 - CIN - 3:12 - 22-yard TD pass from Carson Palmer to Chad Johnson (Graham kick) (CIN 21-20) Q2 - CLE - 1:11 - 25-yard TD pass from Derek Anderson to Kellen Winslow (Dawson kick) (CLE 27-21) Q3 - CIN - 12:13 - Shayne Graham 20-yard FG (CLE 27-24) Q3 - CLE - 8:24 - 34-yard TD pass from Derek Anderson to Braylon Edwards (Dawson kick) (CLE 34-24) Q3 - CIN - 6:18 - 14-yard TD pass from Carson Palmer to Chad Johnson (Graham kick) (CLE 34-31) Q3 - CLE - 6:04 - Jamal Lewis 66-yard TD run (Dawson kick) (CLE 41-31) Q3 - CIN - 0:53 - 5-yard TD pass from Carson Palmer to T. J. Houshmandzadeh (Graham kick) (CLE 41-38) Q4 - CLE - 10:07 - 37-yard TD pass from Derek Anderson to Braylon Edwards (Dawson kick) (CLE 48-38) Q4 - CLE - 5:47 - Phil Dawson 18-yard FG (CLE 51-38) Q4 - CIN - 3:45 - 7-yard TD pass from Carson Palmer to Glenn Holt (Graham kick) (CLE 51-45) 
 Question: Which player completed the seventh longest TD pass of the game?
Output: carson palmer
Context: 28439 Miguelreyes, provisional designation 2000 AM30, is a smaller main-belt asteroid that was discovered on 3 January 2000 by the Lincoln Near-Earth Asteroid Research team at Socorro in New Mexico, United States. 
 Question: The year that 28439 Miguelreyes was discovered was when?
Output: 3 january 2000
Context: The film is a comedy of middle-class French life ' examining culture clashes, puncturing smugness, exposing fault lines, finding strength in romantic and familial relationships and discovering an underlying sadness that stops some way short of tragedy.'[3] The film is set in a small town in Provence during a rainy August. Following the death of her widowed mother Agathe Villanova comes from Paris to deal with the sale of the home where she and her younger sister Florence were brought up, and to announce her entry into politics. She is the author of a feminist best-seller and a divorced film-maker Michel wants to make a TV documentary about her. Michel is having an affair with Agathe's sister. His collaborator is a young Algerian hotel clerk Karim, whose elderly mother has worked for most of her life as a servant with the Villanova family. Agathe's prejudice is put under the microscope when she records a series of interviews with Karim. 'The characters weave around each other for a week or so, occasionally colliding...everyone comes to have a better knowledge of themselves..the dialogue rings true..the ensemble acting is perfect..The film compares favourably with the best of Eric Rohmer.' [4] 
 Question: On which person do Mimouna's son, Karim and his friend Michel Ronsard decide to make a documentary?
Output: agathe
Context: Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by extracellular plaques containing amyloid (A)-protein and intracellular tangles containing hyperphosphorylated Tau protein. Here, we describe the generation of inducible pluripotent stem cell lines from patients harboring the London familial AD (fAD) amyloid precursor protein (APP) mutation (V717I). We examine AD-relevant phenotypes following directed differentiation to forebrain neuronal fates vulnerable in AD. We observe that over differentiation time to mature neuronal fates, APP expression and levels of A increase dramatically. In both immature and mature neuronal fates, the APPV717I mutation affects both - and -secretase cleavage of APP. Although the mutation lies near the -secretase cleavage site in the transmembrane domain of APP, we find that -secretase cleavage of APP is elevated leading to generation of increased levels of both APPs and A. Furthermore, we find that this mutation alters the initial cleavage site of -secretase, resulting in an increased generation of both A42 and A38. In addition to altered APP processing, an increase in levels of total and phosphorylated Tau is observed in neurons with the APPV717I mutation. We show that treatment with A-specific antibodies early in culture reverses the phenotype of increased total Tau levels, implicating altered A production in fAD neurons in this phenotype. These studies use human neurons to reveal previously unrecognized effects of the most common fAD APP mutation and provide a model system for testing therapeutic strategies in the cell types most relevant to disease processes. 
 Question: Which disease the London mutation involved in?
Output: alzheimer's disease
Context: Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by extracellular plaques containing amyloid (A)-protein and intracellular tangles containing hyperphosphorylated Tau protein. Here, we describe the generation of inducible pluripotent stem cell lines from patients harboring the London familial AD (fAD) amyloid precursor protein (APP) mutation (V717I). We examine AD-relevant phenotypes following directed differentiation to forebrain neuronal fates vulnerable in AD. We observe that over differentiation time to mature neuronal fates, APP expression and levels of A increase dramatically. In both immature and mature neuronal fates, the APPV717I mutation affects both - and -secretase cleavage of APP. Although the mutation lies near the -secretase cleavage site in the transmembrane domain of APP, we find that -secretase cleavage of APP is elevated leading to generation of increased levels of both APPs and A. Furthermore, we find that this mutation alters the initial cleavage site of -secretase, resulting in an increased generation of both A42 and A38. In addition to altered APP processing, an increase in levels of total and phosphorylated Tau is observed in neurons with the APPV717I mutation. We show that treatment with A-specific antibodies early in culture reverses the phenotype of increased total Tau levels, implicating altered A production in fAD neurons in this phenotype. These studies use human neurons to reveal previously unrecognized effects of the most common fAD APP mutation and provide a model system for testing therapeutic strategies in the cell types most relevant to disease processes. 
 Question: Which disease the London mutation involved in?
Output: ad
Context: Extrapolating the figures from a previous study on FSHD in a province of The Netherlands to the entire Dutch population suggests that at present a nearly complete overview is obtained of all symptomatic kindred. In 139 families, dominant inheritance was observed in 97, a pattern compatible with germline mosaicism in 6, while sporadic cases were found in 36 families. A mutation frequency of 9.6% was calculated. Mental retardation and severe retinal vasculopathy were reported in low frequencies (1%). Early onset was seen more frequently in sporadic cases. Chromosome 4 linkage appeared excluded in 3 of 22 autosomal-dominant families. The clinical pictures in the linked and nonlinked families were identical. 
 Question: What is the mode of inheritance of Facioscapulohumeral muscular dystrophy (FSHD)?
Output: autosomal dominant
Context: Extrapolating the figures from a previous study on FSHD in a province of The Netherlands to the entire Dutch population suggests that at present a nearly complete overview is obtained of all symptomatic kindred. In 139 families, dominant inheritance was observed in 97, a pattern compatible with germline mosaicism in 6, while sporadic cases were found in 36 families. A mutation frequency of 9.6% was calculated. Mental retardation and severe retinal vasculopathy were reported in low frequencies (1%). Early onset was seen more frequently in sporadic cases. Chromosome 4 linkage appeared excluded in 3 of 22 autosomal-dominant families. The clinical pictures in the linked and nonlinked families were identical. 
 Question: What is the mode of inheritance of Facioscapulohumeral muscular dystrophy (FSHD)?
Output: autosomal-dominant
Context: Restless legs syndrome (RLS) is a clinically important, common disease and should be diagnosed and treated early and adequately. At present, there have been no clinical biomarkers or methodologies that can contribute to the correct diagnosis of RLS, RLS should be diagnosed on the basis of 4 essential criteria: urge to move the legs, improvement after movement, and worsening or occurrence of symptoms in the evening and at rest. When applying the criteria, RLS mimics should be ruled out and comorbid diseases should be taken into account. The origin and pathogenesis of RLS are still under investigation; however, iron deficiency in the brain has been observed on imaging and cerebrospinal fluid analyses of patients with RLS. In contrast, the results of neuroimaging studies evaluating brain dopaminergic functions in patients with RLS have yielded inconclusive results, although involvement of the hypothalamus (A11) is thought to cause impaired dopaminergic modulation in the dorsal horn and intermediolateral nucleus, resulting in the restlessness of legs. 
 Question: Which deficiency is the cause of restless leg syndrome?
Output: iron
Context: The Hungarian Rhapsodies, S.244, R.106 (French: Rhapsodies hongroises, German: Ungarische Rhapsodien, Hungarian: Magyar rapszodiak), is a set of 19 piano pieces based on Hungarian folk themes, composed by Franz Liszt during 1846--1853, and later in 1882 and 1885. 
 Question: On which instrument(s) was Hungarian Rhapsodies created to be played on?
Output: piano
Context: As Tsushima had suffered greatly from its loss of trade with Korea as a result of the invasions, Yoshitoshi of the So family, then dominant in Tsushima, undertook the lead in the peace negotiations by Japan. He sent four peace missions to Joseon in 1599 to normalize relations. The first three were captured and sent directly to Beijing by Chinese troops, but the fourth one, in 1601, successfully obtained from the Joseon court the promise of a normalizing of relations upon the return of remaining Joseon captives. As Ming troops continued to be present in Korea following the withdrawal of Japanese forces, the major incentive for Joseon for the normalization of relations with Japan was the withdrawal of the Chinese soldiers from their territory. The Ming Chinese themselves were causing as much havoc as the Japanese had during the actual conflict, and their presence continued to strain Joseon's national economy and infrastructure. In response to the Joseon request, Yoshitoshi promptly released several Joseon prisoners and between 1603 and 1604 helped the Joseon envoys to repatriate a further 3,000 by organizing negotiations at Kyoto with Tokugawa Ieyasu, by then the Shogun of Japan. In the continuation of the diplomatic talks toward peaceful relations, Joseon in 1606 expanded its conditions and demanded that the Shogun write a formal letter requesting peace, and to extradite the Japanese soldiers who had defiled the Joseon Royal Tombs near Hanseong . Realizing that the Shogunate would never agree to such a request, Yoshitoshi sent a forged letter and a group of criminals instead; the great need to expel the Ming soldiers pushed Joseon into accepting and to send an emissary in 1608. The end result was a return of Joseon prisoners and the restoration of diplomatic and trade relations between the two countries. 
 Question: What happened to the first three peace missions sent To Joseon?
Output: the first three were captured
Context: Though Chad Pennington was active and in uniform for the Jets, the team erred on the side of caution due to injured right ankle, instead starting second-year backup Kellen Clemens, who was making his first career start. The Ravens' defense welcomed him rudely on his first drive with an interception by Ed Reed. The Ravens were able to attain good field position consistently throughout the first half, and quarterback Kyle Boller (who himself was starting in place of an injured starting quarterback, Steve McNair), capitalized with a two-yard touchdown to Willis McGahee late in the first quarter. The teams traded field goals to start the second quarter; Jets kicker Mike Nugent hit a 50-yard field goal, followed by Matt Stover hitting a 28-yard attempt for the Ravens. After Stover missed a 46-yard try, the Jets tried to respond with Nugent attempting a 52-yard field goal, but Nugent missed wide left, his first miss in twenty attempts dating back to last season. Boller once again took advantage of the short field provided and hit tight end Todd Heap on a four-yard touchdown with six seconds left in the half to extend the Ravens' lead to 17-3. Heap's catch was initially ruled incomplete, but the call was subjected to a booth review and reversed, as replays showed he was able to touch both feet within the end zone. After a quiet third quarter, Stover hit a 43-yard field goal to start the fourth quarter, and extended Baltimore's lead to seventeen. Baltimore's defense, which ranked as the best in the NFL in 2006, was able to shut down Clemens and the Jets for most of the game, but Clemens was able to rally the team in the fourth quarter. Using a no huddle offense, Clemens drove the team down to the Baltimore three-yard line, before the Jets settled for a 21-yard field goal. On the Jets' next possession, 44 and 24-yard strikes by Clemens to Jerricho Cotchery got the Jets to the Ravens' goal line, where he found tight end Chris Baker for a three-yard touchdown, cutting the Jets' deficit to seven. Though the Jets failed to convert the ensuing onside kick, poor clock management by Boller gave the Jets the ball back with 2:38 left in the game. Clemens immediately found Cotchery on a 50-yard catch-and-run, later followed by a 24-yard pass to Laveranues Coles that brought the Jets' to the Baltimore seven-yard line with just over a minute to go. Clemens passed to Justin McCareins for a potential touchdown, but the pass was dropped by McCareins. A second pass to McCareins in the end zone deflected off him and into the arms of Ravens linebacker Ray Lewis for the game-ending interception. The loss made the Jets 8-20 since 2002 in games not started by Chad Pennington. 
 Question: Which quarter did not have any points scored?
Output: third quarter
Context: He was the son of The 4th Earl of Clanricarde by his wife Frances Walsingham. Ulick's father was from an Anglo-Norman family who had been long settled in the west of Ireland and had become Gaelicised. Although during the early sixteenth century the family had rebelled against the Crown on several occasions, Ulick's father had been a strong supporter of Queen Elizabeth I. He fought on the Queen's side during Tyrone's Rebellion, notably during the victory at the Battle of Kinsale, where he was wounded. After the war he married the widow of The 2nd Earl of Essex, a recent commander in Ireland, who was the daughter of the English Secretary of State and spymaster Sir Francis Walsingham. In 1622, Ulick married his only wife Anne Compton, the daughter of The 1st Earl of Northampton and his wife, Elizabeth Spencer. They had a single child, Margaret Burgh, who married Viscount Muskerry. Ulick was summoned to the House of Lords as Lord Burgh in 1628, and succeeded his father as 5th Earl of Clanricarde in 1635. In 1636, he inherited Somerhill House on the death of his father. He was a staunch opponent of the policies of the Lord Deputy of Ireland, The 1st Earl of Strafford, who had attempted to seize much of the great Burke inheritance for the Crown; there was also personal ill-feeling between the two men since the dispute was thought by many to have hastened the death of Ulick's elderly father. He sat in the Short Parliament of 1640 and attended King Charles I in the Scottish expedition. Charles, unlike Strafford, liked and trusted Lord Clanricarde. 
 Question: What position did Ulick's father hold?
Output: the 4th earl of clanricarde
Context: Elisabeth of Nuremberg (1358 -- 26 July 1411) was the daughter of Frederick V, Burgrave of Nuremberg and Elisabeth of Meissen. 
 Question: What was the name of Elisabeth of Nuremberg mother?
Output: elisabeth of meissen
Context: GODI is a package management system for the OCaml programming language. 
 Question: What is the programming language for GODI?
Output: ocaml
Context: Fred Fish died at his home in Idaho on Friday April 20, 2007 of a heart attack. 
 Question: From what did Fred Fish die?
Output: heart attack