niryuu/sni-each-converted huggingface dataset:
Context: Three isoforms of human plasma apolipoprotein E (apoE) are ligands to lipoprotein receptors and influence in different manner the synthesis and catabolism of pro-atherogenic triglyceride-rich lipoproteins. Among three isoforms, the apoE4 isoform is associated with increased frequency of atherosclerosis and Alzheimer's disease (AD). The conformational transitions of beta-amyloid (Abeta) influenced by apoE and serum amyloid P (SAP) component are key events in AD development, the accumulation of intermediate diffusible and soluble oligomers of Abeta being of particular significance. SAP and apoE, in a different manner for the three isoforms, serve as "pathological" chaperones during the aggregation of Abeta considered as a conformation-prone process. In turn, apoE consisting of two domains self-associates in solution and intermediate structures differently populated for the three isoforms exist. The different structures of the three isoforms determine their different distribution among various plasma lipoproteins. The structural and metabolic consideration of the common apoE pathway(s) in two pathologies assumes four molecular targets for AD correction: (i) inhibition of the accumulation of diffusible soluble Abeta oligomers; (ii) inhibition of apoE synthesis and secretion by astrocytes, in particular, under lipid-lowering therapy; (iii) inhibition of the binding of apoE and/or SAP to Abeta; (iv) stimulation of the expression of cholesterol transporter ABCA1. 
 Question: Which ApoE isoform is associated with atherosclerosis and Alzheimer's disease?
Output: apolipoprotein e4 isoform
Context: To determine the validity of the rapid antigen test (RAT) OSOM StrepA Genzyme for the diagnosis of acute pharyngitis caused by group A beta-haemolytic strep (GABHS). Diagnostic techniques survey. Urban primary care centre, Spain. All patients over 14 years old seen in 6 surgeries with sore throat and 2 or more Centor criteria: pharyngotonsillar exudate, tender laterocervical nodes, absence of coughing, and/or history or presence of fever. Pharyngeal swabs were taken from all the patients, one for RAT and another to send for culture in the microbiology department. A total of 182 patients were evaluable, with a mean age of 30.6 (12.1) years of which 116 were women (63.7%); 63 patients had 2 Centor criteria; 83 had 3 and 36, the 4 criteria. The culture was positive in 102 patients (56%), with GABHS showing infection in forty (22%; 95% confidence interval [CI], 21.2-22.8). Group C Streptococcus was isolated in 26 patients (14.3%). GABHS was higher among patients with four Centor criteria (38.9% vs 25.3% observed among those with 3 criteria and 7.9% with 2 criteria; P<.001). Sensitivity of RAT was 95%, with a specificity of 93%, a positive predictive value of 79.2% and a negative predictive value of 98.5%. These results show the usefulness of RAT for diagnosing streptococcal pharyngitis. Its use should be spread to all primary care practices. 
 Question: Centor criteria are used for which disease?
Output: streptococcal pharyngitis
Context: Fat on human body is distributed in two different ways. Some fat people have a large chest and no waistline , looking rather like apples. Others are fatter below the waist, looking more like pears. Doctors in Cambridge, England have been examining the relationship between health and fat distribution. They find that the pear-shaped fat people have fewer problems than the apple-shaped people. What seems to be most important is not just how much fat you have but where you have it. The doctors measured the apple-shaped women and pear-shaped women and examined them with X-ray scanners (X). Human beings have two types of fat, one is outside fat that is the fat below the skin and the other is inside fat that lies inside the body. Using the X-ray scanners, the doctors found that the "apples" have a large amount of inside fat. If this inside fat is much more than outside fat, it will probably cause health problems such as obesity . The best treatment for obesity is to reduce the inside fat. But unfortunately diet treatment simply makes an apple-shaped person into a smaller apple and a pear-shaped person into a smaller pear. At the moment there is no effective way of reducing the inside fat. 
 Question: If you are fatter below your hip you are
Output: a pear-shaped person
Context: The Internet can be a great way to connect with people. The latest web craze is social networking on websites such as MySpace. More than 65 million young people use online social networking sites. That cyberspace trend is causing problems in school, however. In a recent survey, nearly 36 percent of school administrators said that social networking sites troubled learning in their districts. Should school districts ban sites like MySpace? Teachers are worried that some students use social networking to post personal information and to cyber bully other students. One of the biggest dangers comes from people who find out kid's personal information. Many districts have blocked students from accessing or using social networking sites from school computers, and some have suspended students for posting harmful material on those sites from their home computers. Nearly two-thirds of US kids have computers in their homes, according to the US Census Bureau. "It is important to keep in mind that just blocking access to social web sites at school is not the end of the story," warns NSBA executive director Anne Bryant, "Most of the misuse of these sites takes place at home but still affects the classroom." _ . They say the main problem with sites like MySpace is that students don't understand the dangers involved in using them. "Many students are posting personal information about themselves without regard to who has access to that information," Jim Hirsch said, "Schools should focus on educating their students and their parents on how to be safe online." Experts argue that too many schools are forbidding students to use social networking web sites without thinking about their educational benefits. "Social networking web sites can help connect students in the United States to their peers in other countries, providing invaluable lessons in foreign cultures," explains Hirsch. 
 Question: Where do students usually misuse social networking sites?
Output: at home.
Context: Inherited ventricular arrhythmias such as the long QT syndrome (LQTS), Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia (CPVT), idiopathic ventricular fibrillation (VF), and arrhythmogenic right ventricular cardiomyopathy (ARVC) account for a relevant proportion of sudden cardiac death cases in young patients cohorts. The detailed pathogenetic mechanisms of inherited ventricular arrhythmias are still poorly understood because systematic investigations are difficult to perform due to low patient numbers and the lack of appropriate experimental models. However, recent advances in research and science have identified a genetic background for many of these diseases. In LQTS, various mutations in different genes encoding for cardiac potassium and sodium channel proteins have been identified ("channelopathy"), and initial progress in genotype-phenotype correlation is made. Mutations in the cardiac sodium channel gene have also been identified in a subset of patients with Brugada syndrome, whereas a genetic background has not yet been demonstrated in idiopathic VF and right ventricular outflow-tract tachycardia (RVO-VT). Very recently, mutations in the cardiac ryanodine receptor gene have been identified in CPVT and in a subgroup of patients with ARVC. Although several chromosomal loci were suggested, no other responsible genes or mutations have been found in autosomal dominant forms of ARVC. However, in Naxos disease, a recessive form of ARVC with coexpression of palmoplantar keratoderma and woolly hair, a mutation in the plakoglobin gene has recently been discovered, thus underscoring the potential role of genetic alterations in cytoskeletal proteins in ARVC. In the next years, significant progress in the genetic diagnosis pathophysiologic understanding of disease mechanisms, genotype-phenotype correlation, and the development of gene- or target-directed treatment strategies can be expected in the field of inherited ventricular arrhythmias. This review summarizes the current knowledge of the molecular mechanisms, including aspects of pathoanatomy, autonomic innervation, genetics, and genotype-phenotype correlations with their potential implications for diagnosis and treatment of inherited ventricular arrhythmias. 
 Question: Which gene is mutated in a subtype of arrhythmogenic right ventricular cardiomyopathy known as Naxos disease?
Output: plakoglobin[jup]
Context: Inherited ventricular arrhythmias such as the long QT syndrome (LQTS), Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia (CPVT), idiopathic ventricular fibrillation (VF), and arrhythmogenic right ventricular cardiomyopathy (ARVC) account for a relevant proportion of sudden cardiac death cases in young patients cohorts. The detailed pathogenetic mechanisms of inherited ventricular arrhythmias are still poorly understood because systematic investigations are difficult to perform due to low patient numbers and the lack of appropriate experimental models. However, recent advances in research and science have identified a genetic background for many of these diseases. In LQTS, various mutations in different genes encoding for cardiac potassium and sodium channel proteins have been identified ("channelopathy"), and initial progress in genotype-phenotype correlation is made. Mutations in the cardiac sodium channel gene have also been identified in a subset of patients with Brugada syndrome, whereas a genetic background has not yet been demonstrated in idiopathic VF and right ventricular outflow-tract tachycardia (RVO-VT). Very recently, mutations in the cardiac ryanodine receptor gene have been identified in CPVT and in a subgroup of patients with ARVC. Although several chromosomal loci were suggested, no other responsible genes or mutations have been found in autosomal dominant forms of ARVC. However, in Naxos disease, a recessive form of ARVC with coexpression of palmoplantar keratoderma and woolly hair, a mutation in the plakoglobin gene has recently been discovered, thus underscoring the potential role of genetic alterations in cytoskeletal proteins in ARVC. In the next years, significant progress in the genetic diagnosis pathophysiologic understanding of disease mechanisms, genotype-phenotype correlation, and the development of gene- or target-directed treatment strategies can be expected in the field of inherited ventricular arrhythmias. This review summarizes the current knowledge of the molecular mechanisms, including aspects of pathoanatomy, autonomic innervation, genetics, and genotype-phenotype correlations with their potential implications for diagnosis and treatment of inherited ventricular arrhythmias. 
 Question: Which gene is mutated in a subtype of arrhythmogenic right ventricular cardiomyopathy known as Naxos disease?
Output: the plakoglobin gene
Context: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.24.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosis) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto's thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. 
 Question: What chromosome is affected in Turner's syndrome?
Output: x
Context: Mitochondrial (mt) genomes from diverse phylogenetic groups vary considerably in size, structure and organization. The genus Plasmodium, the causative agent of malaria, has the smallest mt genome in the form of a tandemly repeated, linear element of 6 kb. The Plasmodium mt genome encodes only three protein genes (cox1, cox3 and cob) and large- and small-subunit ribosomal RNA (rRNA) genes, which are highly fragmented with 19 identified rRNA pieces. The complete mt genome sequences of 21 Plasmodium species have been published but a thorough investigation of the arrangement of rRNA gene fragments has been undertaken for only Plasmodium falciparum, the human malaria parasite. In this study, we determined the arrangement of mt rRNA gene fragments in 23 Plasmodium species, including two newly determined mt genome sequences from P. gallinaceum and P. vinckei vinckei, as well as Leucocytozoon caulleryi, an outgroup of Plasmodium. Comparative analysis reveals complete conservation of the arrangement of rRNA gene fragments in the mt genomes of all the 23 Plasmodium species and L. caulleryi. Surveys for a new rRNA gene fragment using hidden Markov models enriched with recent mt genome sequences led us to suggest the mtR-26 sequence as a novel candidate LSU rRNA fragment in the mt genomes of the 24 species. Additionally, we found 22-25 bp-inverted repeat sequences, which may be involved in the generation of lineage-specific mt genome arrangements after divergence from a common ancestor of the genera Eimeria and Plasmodium/Leucocytozoon. 
 Question: Which is the causative agent of malaria?
Output: plasmodium species
Context: Mitochondrial (mt) genomes from diverse phylogenetic groups vary considerably in size, structure and organization. The genus Plasmodium, the causative agent of malaria, has the smallest mt genome in the form of a tandemly repeated, linear element of 6 kb. The Plasmodium mt genome encodes only three protein genes (cox1, cox3 and cob) and large- and small-subunit ribosomal RNA (rRNA) genes, which are highly fragmented with 19 identified rRNA pieces. The complete mt genome sequences of 21 Plasmodium species have been published but a thorough investigation of the arrangement of rRNA gene fragments has been undertaken for only Plasmodium falciparum, the human malaria parasite. In this study, we determined the arrangement of mt rRNA gene fragments in 23 Plasmodium species, including two newly determined mt genome sequences from P. gallinaceum and P. vinckei vinckei, as well as Leucocytozoon caulleryi, an outgroup of Plasmodium. Comparative analysis reveals complete conservation of the arrangement of rRNA gene fragments in the mt genomes of all the 23 Plasmodium species and L. caulleryi. Surveys for a new rRNA gene fragment using hidden Markov models enriched with recent mt genome sequences led us to suggest the mtR-26 sequence as a novel candidate LSU rRNA fragment in the mt genomes of the 24 species. Additionally, we found 22-25 bp-inverted repeat sequences, which may be involved in the generation of lineage-specific mt genome arrangements after divergence from a common ancestor of the genera Eimeria and Plasmodium/Leucocytozoon. 
 Question: Which is the causative agent of malaria?
Output: plasmodium spp.
Context: Soil is a complex mixture of different materials. About half of most soils are inorganic materials, such as the products of weathered rock, including pebbles, sand, silt, and clay particles. About half of all soils are organic materials, formed from the partial breakdown and decomposition of plants and animals. The organic materials are necessary for a soil to be fertile. The organic portion provides the nutrients, such as nitrogen, needed for strong plant growth. In between the solid pieces, there are tiny spaces filled with air and water. Within the soil layer, important reactions between solid rock, liquid water, air, and living things take place. In some soils, the organic portion could be missing, as in desert sand. Or a soil could be completely organic, such as the materials that make up peat in a bog or swamp (Figure 1.1). The inorganic portion of soil is made of many different size particles, and these different size particles are present in different proportions. The combination of these two factors determines some of the properties of the soil. A permeable soil allows water to flow through it easily because the spaces between the inorganic particles are large and well connected. Sandy or silty soils are considered "light" soils because they are permeable, water-draining types of soils. Soils that have lots of very small spaces are water-holding soils. For example, when clay is present in a soil, the soil is heavier, holds together more tightly, and holds water. When a soil contains a mixture of grain sizes, the soil is called a loam (Figure 1.2). A loam field. When soil scientists want to precisely determine soil type, they measure the percentage of sand, silt, and clay. They plot this information on a triangular diagram, with each size particle at one corner (Figure 1.3). The soil type can then be determined from the location on the diagram. At the top, a soil would be clay; at the left corner, it would be sand; at the right corner, it would be silt. Soils in the lower middle with less than 50% clay are loams. Soil types by particle size. Soil is an ecosystem unto itself. In the spaces of soil, there are thousands or even millions of living organisms. Those organisms could include earthworms, ants, bacteria, or fungi (Figure 1.4). 
 Question: which of these are inorganic materials?
Output: pebbles
Context: Coming off their Sunday night road win over the Packers, the Cowboys went home for a Week 4 NFC East showdown with the Washington Redskins. In the first quarter, the 'Boys shot first as QB Tony Romo completed a 21-yard TD pass to TE Jason Witten. In the second quarter, the Redskins took the lead as QB Jason Campbell completed a 3-yard TD pass to WR James Thrash and a 2-yard TD pass to WR Antwaan Randle El, along with kicker Shaun Suisham getting a 20-yard field goal. Dallas closed out the half with kicker Nick Folk getting a 36-yard field goal. In the third quarter, the Cowboys tied the game with Romo completing a 10-yard TD pass to WR Terrell Owens. Washington would respond with Suisham kicking a 33-yard field goal. In the fourth quarter, the Redskins increased their lead with Suisham nailing a 33-yard and a 29-yard field goal. The 'Boys tried to rally as Romo completed an 11-yard TD pass to WR Miles Austin. However, Dallas' onside kick attempt failed, preserving the Redskins' win. 
 Question: Which player scored the last field goal of the game?
Output: shaun suisham
Context: It's no secret that doing good makes others happy - but did you know it can make you happy as well? According to a study, people participating in meaningful activities were happier and felt that their lives had more purpose than people who only engaged in pleasure-seeking behaviors. Try giving these four things to others to start your journey to a happier and healthier lifestyle. 1. Your Time With a busy life, it can be hard to find any time to give away. However, volunteering your time has great benefits, including making new friends and connections, learning new skills and even advancing your career. According to a paper about the link between health and volunteering, volunteering is connected with lower instances of depression and reduces the risk of dying by 22 percent. 2. Your Attention Most of us think we're good listeners, but according to psychologist Paul Donoghue, most people are aware that others don't listen as well as they could. In addition, they're not fully aware that they themselves aren't listening. When practicing mindfulness meditation , you focus on what you experience in the moment and let your thoughts and emotions pass through without judgment. Did you know that giving someone your undivided attention helps you also? When done well, active listening strengthens your focus-which is a major part of good meditation. 3. Your Compassion The psychological meaning of compassion is the ability to understand another person's emotional state. Compassion differs from empathy in that those who experience compassion not only put themselves in another person's shoes, but also want to reduce that person's suffering. A brain-imaging study showed that the brain's pleasure centers are equally active when we give money to the poor as when we receive money ourselves. 4. Your Money According to an experiment, those who spend money on other people are significantly happier than those who spend the same quantity of money on themselves. Whether or not you can offer other gifts, donating money helps make real change happen. It represents time spent, compassion and careful attention to the needs of others. 
 Question: Which of the four gifts matters most according to the author?
Output: money.
Context: Matt and his wife lived in the country. Matt was very mean and hated spending money. One day a fair came to the nearby town. They went to the fair and looked at all the things to buy. Matt's wife wanted to buy a hat only costing $28, but was refused. Later on, a comb of $5 attracted her attention, but he would not let her spend any money. Then, in a nearby field, they saw a small airplane. "Fun flight!" the notice said, "$10 for 10 minutes." Matt had never been in an airplane and he wanted to go on a fun flight. However, he didn't want to pay for his wife either. "I've only got $10," he told the pilot. "Can my wife come with me for free?" The pilot wasn't selling many tickets, so he said, "I'll make a bargain with you. If your wife doesn't scream, she can have a free flight." Matt agreed, and got into the small airplane with his wife. The pilot took off and made his airplane do all kinds of things. At one moment it was flying upside down. When the plane landed, the pilot said, "OK, your wife didn't make a sound. She can have her ride free." "Thank you," Matt said, "it wasn't easy for her, you know, especially when she fell out." 
 Question: How much did the couple spend at the fair?
Output: $10.
Context: Australia has promised to introduce the most comprehensive carbon trading program outside Europe in 2010. The government in Canberra plans to cut greenhouse gas emissions by at least five percent by 2020, but it could make bigger reductions if other countries agree to tougher targets. The Australian government warns that without tough environmental measures the country could lose key industries and jobs. Climate Change Minister Penny Wong says the economy is under threat and decisive action is needed. Central to the government's climate change plan is a carbon emissions trading program that will be introduced within two years. It would involve one thousand of the nation's biggest companies and would cover about three-quarters of Australia's greenhouse gas emissions. Many scientists believe that greenhouse gases, such as carbon dioxide and methane, contribute to global warming. Many of them are released by burning fuels such as coal and oil. Companies will be required to buy permits for each ton of carbon they emit, although big polluting exporters will receive up to 90 percent of their carbon licenses free. Many business leaders want the government to delay the plan because of the current global financial crisis, which is slowing the Australian economy. Peter Anderson from the Australian Chamber of Commerce and Industry says it is irresponsible to bring in a carbon trading plan now. Environmentalists, on the other hand, say Prime Minister Kevin Rudd has not properly addressed the threat of climate change. Activists had sought a minimum emissions cut of 25 percent. Instead, the Rudd government aims to cuts carbon emissions by at least five percent of 2000 levels by 2020. That amount could rise to 15 percent, if future global agreements set such a target. Ray Nias of the environmental group WWF says Australia will pay the price for low targets. "This is a deeply, deeply disappointing target," Nias said. "It commits Australia to long-term climate change. It will make Australia's ability to negotiate global agreements very, very difficult. It is much lower than even we had imagined." Australia has one of the highest per-person greenhouse emissions rates in the world because of its reliance on coal for electricity. _ 
 Question: Which group supports to cut carbon emissions by at least 25%?
Output: environmentalists.
Context: Coming off their home win over the Lions, the 49ers flew to the Louisiana Superdome for a Week 4 duel with the New Orleans Saints. In the first quarter, the Niners struck first as kicker Joe Nedney got a 47-yard field goal. In the second quarter, the Saints took the lead with QB Drew Brees completing a 5-yard and a 33-yard TD pass to WR Lance Moore. San Francisco would answer with Nedney's 49-yard field goal, yet New Orleans replied with Brees' 47-yard TD pass to WR Robert Meachem. In the third quarter, the 49ers tried to rally as Nedney kicked a 38-yard field goal. However, in the fourth quarter, the Saints continued to pull away as RB Deuce McAllister got a 1-yard TD run. The Niners tried to rally as QB J.T. O'Sullivan completed a 5-yard TD pass to WR Isaac Bruce, yet New Orleans sealed the win with kicker Martin Gramatica nailing a 31-yard field goal. 
 Question: Which team had the shortest field goal
Output: saints
Context: Coming off their home win over the Lions, the 49ers flew to the Louisiana Superdome for a Week 4 duel with the New Orleans Saints. In the first quarter, the Niners struck first as kicker Joe Nedney got a 47-yard field goal. In the second quarter, the Saints took the lead with QB Drew Brees completing a 5-yard and a 33-yard TD pass to WR Lance Moore. San Francisco would answer with Nedney's 49-yard field goal, yet New Orleans replied with Brees' 47-yard TD pass to WR Robert Meachem. In the third quarter, the 49ers tried to rally as Nedney kicked a 38-yard field goal. However, in the fourth quarter, the Saints continued to pull away as RB Deuce McAllister got a 1-yard TD run. The Niners tried to rally as QB J.T. O'Sullivan completed a 5-yard TD pass to WR Isaac Bruce, yet New Orleans sealed the win with kicker Martin Gramatica nailing a 31-yard field goal. 
 Question: Which team had the shortest field goal
Output: new orleans
Context: This article needs an improved plot summary. (November 2015) The Cake Eaters is a small-town, ensemble drama that explores the lives of two interconnected families coming to terms with love in the face of loss. Living in rural America, the Kimbrough family are a conflicted bunch: Easy, the patriarch and local butcher, is grieving over the recent loss of his wife, Ceci, while hiding a secret ongoing affair for years; Beagle, his youngest son who was left to care for his ailing mother, works in the local high school cafeteria by day but has a burning passion inside that manifests itself through painting street signs; and the eldest son, Guy, has been away from the family for years while pursuing his rock star dream in the big city until the day he learns of his mother's death and that he has missed the funeral. Upon Guy's return home, relationships between the characters begin to unravel: Beagle's pent up emotions connect with Georgia Kaminski, a terminally ill teenage girl wanting to experience love before it is too late; Easy's long-time affair with Marg, Georgia's eccentric grandmother, is finally exposed to the Kimbrough children; and Guy discovers that in his absence his high school sweetheart, Stephanie, has moved on and started a family of her own. Consequently, The Kimbroughs and Kaminskis manage to establish new beginnings in facing their varied relationships. 
 Question: Who is the terminally ill teenage girl?
Output: georgia kaminski
Context: The Seahawks began their 2008 campaign on the road against the Buffalo Bills. In the first quarter, Seattle trailed early as Bills RB Marshawn Lynch got a 21-yard TD run. In the second quarter, the Seahawks continued to struggle as WR/PR Roscoe Parrish returned a punt 63 yards for a touchdown. Seattle responded with QB Matt Hasselbeck completing a 20-yard TD pass to WR Nate Burleson. Buffalo closed out the half with kicker Rian Lindell getting a 35-yard and a 38-yard field goal. In the third quarter, the Seahawks replied with kicker Olindo Mare nailing a 45-yard field goal. However, the Bills pulled a trick play on Seattle. Appearing to go for a 32-yard field goal, Buffalo's holder (punter Brian Moorman) instead threw a 19-yard TD pass to DE Ryan Denney. The Bills pulled away with QB Trent Edwards completing a 30-yard TD pass to TE Robert Royal. 
 Question: Which player kicked the longest field goal of the game?
Output: olindo mare
Context: The Exquisite Thief is a 1919 American silent drama film directed by Tod Browning. 
 Question: Who was the director for The Exquisite Thief?
Output: tod browning
Context: The McLeod phenotype is derived from various forms of XK gene defects that result in the absence of XK protein, and is defined hematologically by the absence of Kx antigen, weakening of Kell system antigens, and red cell acanthocytosis. Individuals with the McLeod phenotype usually develop late-onset neuromuscular abnormalities known as the McLeod syndrome (MLS). MLS is an X-linked multi-system disorder caused by absence of XK alone, or when the disorder is caused by large deletions, it may be accompanied with Duchenne muscular dystrophy (DMD), chronic granulomatous disease (CYBB), retinitis pigmentosa (RPGR), and ornithine transcarbamylase deficiency (OTC). XK defects derived from a large deletion at the XK locus (Xp21.1) have not been characterized at the molecular level. In this study, the deletion breakpoints of two novel cases of McLeod phenotype with extensive deletions are reported. Case 1 has greater than 1.12 million base-pairs (mb) deletion around the XK locus with 7 genes affected. Case 2 has greater than 5.65 mb deletion from TCTE1L to DMD encompassing 20 genes. Phylogenetic analyses demonstrated that DMD, XK and CYBB have close paralogs, some of which may partially substitute for the functions of their counterparts. The loci around XK are highly conserved from fish to human; however, the disorders are probably specific to mammals, and may coincide with the translocation of the loci to the X chromosome after the speciation in birds. The non-synonymous to synonymous nucleotide substitution rate ratio (omega=dN/dS) in these genes was examined. CYBB and RPGR show evidence of positive selection, whereas DMD, XK and OTC are subject to selective constraint. 
 Question: Mutation of which gene is associated with McLeod syndrome?
Output: xk
Context: The Noleby Runestone is now located in the Swedish Museum of National Antiquities in Stockholm. 
 Question: What is the name of the place where Noleby Runestone can be found?
Output: swedish museum of national antiquities
Context: In the Night Garden In a magical forest, colourful characters have adventures. A mysterious tide of water appears suddenly next to Igglepiggle. He discovers that he can control it by moving his feet. Excited, he takes it to Makka Pakka who finds it very useful indeed. Children Under 5 Today on BBC2 from 11:05am to 11:35am Last of the Summer Wine To relax, Howard tries a simple trick to change his appearance enough to fool even Pearl. But he soon discovers that taking over someone else's identity can be equally dangerous. Comedy Sitcoms Today on G.O.L.D. from 12:40pm to 1: 20pm The Secret Circle Cassie is an orphaned teenager who discovers that not only is she a witch but that she is also the key that will unlock a centuries-old battle between good and evil. When Cassie accepts a cute boy's invitation to the school dance, Adam struggles to control his anger. Today on Sky Living from 10:00pm to 11:00pm The Kid's Speech Eleven-year-olds, Reggie and William, and 14-year-old Bethan, are determined to improve their speech. Along with their parents, they start a unique course at the Michael Palin Centre for Stammering children. Over two weeks, they open up about their fears and frustrations. Documentary Today on BBC1 London from 10:35pm to 11:25pm 
 Question: Which play can be used to inspire children who are afraid to speak in public?
Output: the kid's speech.
Context: May : Happenings from the past May 5,1884 Isaac Murphy , son of a slave and perhaps the greatest horse rider in American history , rides Buchanan to win his first Kentucky Derby . He becomes the first rider ever to win the race three times . May 9 , 1754 Benjamin Franklin's Pennsylvania Gazette produces perhaps the first American political cartoon , showing a snake cut in pieces, with the words " Join or Die" printed under the picture. May 11,1934 The first great dust storm of the Great Plains Dust Bowl , the result of years of drought,blows topsoil all the way to New York City and Washington , D.C. . May 19, 1994 Jacqueline Lee Bouvier Kennedy Onassis , former first lady and one of the most famous people of the 1960s , died of cancer in New York City at the age of 64 . May 24, 1844 Samuel F.B. Morsr taps out the first message , " What Hath God Wrought ," over the experimental long-distance telegraph line which runs from Washington, D.C. , to Baltimeore , Md . 
 Question: In which year did the former first lady Jacqueline die ?
Output: 1994
Context: Printemps was noted for its branding innovations as well, handing out bouquets of violets on the first day of each Spring and championing the new Art Nouveau style, with its nature inspired motifs. 
 Question: The art style of Printemps is what?
Output: art nouveau
Context: During the war, the Russian army organized the Crimean campaigns of 1687 and 1689 both which ended in Russian defeats. Despite these setbacks, Russia launched the Azov campaigns in 1695 and 1696, and after raising the siege in 1695 successfully occupied Azov in 1696. 
 Question: What happened first, the Azov campaigns or the Crimean campaigns?
Output: azov campaigns
Context: According to the market research firm SuperData, as of May 2015, the global games market was worth USD 74.2 billion. By region, North America accounted for $23.6 billion, Asia for $23.1 billion, Europe for $22.1 billion and South America for $4.5 billion. By market segment, mobile games were worth $22.3 billion, retail games 19.7 billion, free-to-play Massively multiplayer online game 8.7 billion, social games $7.9 billion, PC Downloadable content 7.5 billion, and other categories $3 billion or less each. 
 Question: Which area accounted for more of the games market, Asia or Europe?
Output: asia
Context: Located at 1 Court Street and Washington Mall in downtown Boston, the Ames Building was designed by the architectural firm of Shepley, Rutan and Coolidge in Richardsonian Romanesque and paid for by Frederick L. Ames. 
 Question: Which is the kind of art style of Ames Building?
Output: richardsonian romanesque
Context: In patients with active rheumatoid arthritis despite therapy with DMARDS, treatment with a spleen tyrosine kinase inhibitor has achieved similar response rates to those achieved in clinical trials of other drugs, including biologic agents. Where might these agents fit in the current armamentarium against this disease? 
 Question: Which enzyme is inhibited by a drug fostamatinib?
Output: spleen tyrosine kinase
Context: Does everyone want a challenging job? In spite of all the attention focused by the media, academicians, and social scientists on human potential and the needs of individuals, there is no evidence to support that the vast majority of workers want challenging jobs. Some individuals prefer highly complex and challenging jobs; others develop in simple, routine work. The individual-difference variable that seems to gain the greatest support for explaining who prefers a challenging job and who doesn't is the strength of an individual's needs for personal growth and self-direction at work. Individuals with these higher-order growth needs are more responsive for challenging work. What percentage of ordinary workers actually desire higher-order need satisfactions and will respond positively to challenging jobs? No current data is available, but a study from the 1970s estimated the figure at about 15%. Even after adjusting for changing work attitudes and the growth in white-collar jobs, it seems unlikely that the number today exceeds 40%. The strongest voice advocating challenging jobs has not been workers--it's been professors, social science researchers, and media people. Professors, researchers, and journalists undoubtedly made their career choices, to some degree, because they wanted jobs that gave them autonomy, recognition and challenge. That, of course, is their choice. But for them, to force their needs onto the workforce in general is presumptuous . Not every employee is looking for a challenging job. Many workers meet their higher-order need off the job. There are 168 hours in every individual's week. Work rarely consumes more than 30% of this time. That leaves considerable opportunities, even for individuals with strong growth needs, to find higher-order need satisfaction outside the workplace. So don't feel you have a responsibility to create challenging jobs for all your employees. For many people, work is something that will never excite or challenge them. And they don't expect to find their growth opportunities at work. Work is merely something they have to do to pay their bills. They can find challenges outside of work on the golf course, fishing, at their local pub, with their friends in social clubs, with their family, and the like. 
 Question: What makes people choose challenging jobs?
Output: higher-order growth needs.
Context: Coming off their last-second victory over the Bengals, the Broncos would play their Week 2 home opener against the Cleveland Browns. In the first quarter, Denver would trail early as Browns kicker Phil Dawson got a 22-yard field goal. Afterwards, the Broncos took the lead as quarterback Kyle Orton completed a 2-yard touchdown pass to tight end Tony Scheffler. Cleveland would creep close as Dawson made a 47-yard field goal, but Denver would answer as kicker Matt Prater got a 23-yard field goal in the second quarter and a 38-yard field goal in the third quarter. In the fourth, the Broncos pulled away as fullback Peyton Hillis got a 2-yard touchdown run and running back Correll Buckhalter got a 45-yard touchdown run. 
 Question: Which kicker had more total yards?
Output: dawson
Context: Sir John's considerable wealth in Barbados passed to his son, Major Sir William Yeamans, second baronet, and great-grandfather of Sir John Yeamans of Barbados, whose son, Sir Robert (d. 19 February 1788), was the last baronet. 
 Question: What was the title that John Yeamans held?
Output: baronet
Context: Arthur Klemt (born 1913 in Offenburg, Baden-Wurttemberg, Germany -- died 1985 in Olching, Bavaria, Germany) was a German inventor. 
 Question: Where did Arthur Klemt live when he died?
Output: olching
Context: The Steelers stayed home for a 3-game home stand and for a Sunday Night duel against the Ravens. The Ravens scored first when Joe Flacco hooked up with Torrey Smith 35-yard TD pass to take a 7-0 lead for the only score of the first quarter. In the 2nd quarter, the Steelers managed to tie the game up when Ben Roethlisberger found Le'Veon Bell on a 5-yard TD pass for a 7-7 game. They eventually took the lead when Roethlisberger found Martavis Bryant on a 19-yard TD pass to make it a 14-7 game. The Ravens came within 4 as Justin Tucker kicked a 46-yard field goal to make it 14-10 game. However, the Steelers would manage to go ahead by 12 before halftime when Roethlisberger found Markus Wheaton on a 47-yard TD pass followed by a successful 2-point conversion for a 22-10 lead at halftime. After a scoreless 3rd quarter, the Steelers came out strong and went back to work in the 4th when Roethlisberger found Antonio Brown on a 54-yard TD pass making the score 29-10. The Ravens responded with a big play as Jacoby Jones ran a 108-yard kickoff return for a TD to make it a 29-17 game. Roethlisberger found Bryant again on an 18-yard TD pass to make the score 36-17. This was followed by the Ravens trying their hand at coming back when Flacco found Crockett Gillmore on a 1-yard TD pass (with a failed 2-point conversion) for a 36-23 score. But the Steelers were able to seal the game when Roethlisberger found Matt Spaeth on a 33-yard TD pass for a final score of 43-23. A week after passing for a franchise-record six touchdowns against Indianapolis, Roethlisberger duplicated the feat to lead Pittsburgh to its third consecutive win. The 12 touchdown passes over the last two games broke the NFL record of 11 set by Tom Flores for Oakland in the AFL in 1963 and matched by New England's Tom Brady in 2007. 
 Question: Which slot was this game being played in?
Output: sunday night
Context: MicroRNAs (miRNAs) are non-coding, short (21-23nt) regulators of protein-coding genes that are generally transcribed first into primary miRNA (pri-miR), followed by the generation of precursor miRNA (pre-miR). This finally leads to the production of the mature miRNA. A large amount of information is available on the pre- and mature miRNAs. However, very little is known about the pri-miRs, due to a lack of knowledge about their transcription start sites (TSSs). Based on the genomic loci, miRNAs can be categorized into two types --intragenic (intra-miR) and intergenic (inter-miR). While it is already an established fact that intra-miRs are commonly transcribed in conjunction with their host genes, the transcription machinery of inter-miRs is poorly understood. Although it is assumed that miRNA promoters are similar in structure to gene promoters, since both are transcribed by RNA polymerase II (Pol II), computational validations exhibit poor performance of gene promoter prediction methods on miRNAs. In this paper, we concentrate on the problem of TSS prediction for miRNAs. The present study begins with the identification of positive and negative promoter samples from recently published data stemming from RNA-sequencing studies. From these samples of experimentally validated miRNA TSSs, a number of standard sequence features are extracted. Furthermore, to account for potential footprints related to promoter regulation by CpG dinucleotide targeted DNA methylation, a number of novel features are defined. We develop a support vector machine (SVM) with RBF kernel for the prediction of miRNA TSSs trained on human miRNA promoters. A novel feature reduction technique based on archived multi-objective simulated annealing (AMOSA) identifies the final set of features. The resulting model trained on miRNA promoters shows improved performance over the one trained on protein-coding gene promoters in terms of classification accuracy, sensitivity and specificity. Results are also reported for a completely independent biologically validated test set. In a part of the investigation, the proposed approach is used to predict protein-coding gene TSSs. It shows a significantly improved performance when compared to previously published gene TSS prediction methods. 
 Question: Which polymerase transcribes pri-miRNAs?
Output: rnapii
Context: MicroRNAs (miRNAs) are non-coding, short (21-23nt) regulators of protein-coding genes that are generally transcribed first into primary miRNA (pri-miR), followed by the generation of precursor miRNA (pre-miR). This finally leads to the production of the mature miRNA. A large amount of information is available on the pre- and mature miRNAs. However, very little is known about the pri-miRs, due to a lack of knowledge about their transcription start sites (TSSs). Based on the genomic loci, miRNAs can be categorized into two types --intragenic (intra-miR) and intergenic (inter-miR). While it is already an established fact that intra-miRs are commonly transcribed in conjunction with their host genes, the transcription machinery of inter-miRs is poorly understood. Although it is assumed that miRNA promoters are similar in structure to gene promoters, since both are transcribed by RNA polymerase II (Pol II), computational validations exhibit poor performance of gene promoter prediction methods on miRNAs. In this paper, we concentrate on the problem of TSS prediction for miRNAs. The present study begins with the identification of positive and negative promoter samples from recently published data stemming from RNA-sequencing studies. From these samples of experimentally validated miRNA TSSs, a number of standard sequence features are extracted. Furthermore, to account for potential footprints related to promoter regulation by CpG dinucleotide targeted DNA methylation, a number of novel features are defined. We develop a support vector machine (SVM) with RBF kernel for the prediction of miRNA TSSs trained on human miRNA promoters. A novel feature reduction technique based on archived multi-objective simulated annealing (AMOSA) identifies the final set of features. The resulting model trained on miRNA promoters shows improved performance over the one trained on protein-coding gene promoters in terms of classification accuracy, sensitivity and specificity. Results are also reported for a completely independent biologically validated test set. In a part of the investigation, the proposed approach is used to predict protein-coding gene TSSs. It shows a significantly improved performance when compared to previously published gene TSS prediction methods. 
 Question: Which polymerase transcribes pri-miRNAs?
Output: rna polymerase ii
Context: As of the 2010 United States Census, there were 1,951,269 people, 715,365 households, and 467,916 families residing in the county. The population density was . There were 840,343 housing units at an average density of . The racial makeup of the county was 60.9% white, 10.5% black or African American, 8.7% Asian, 0.7% Pacific islander, 0.7% American Indian, 13.5% from other races, and 5.1% from two or more races. Those of Hispanic or Latino origin made up 29.1% of the population. In terms of ancestry, 11.7% were Germans, 9.1% were Irish people, 7.6% were English people, 6.3% were Italians, and 2.7% were Americans. 
 Question: Which group from the census is smaller: Pacific islander or two or more races?
Output: pacific islander