niryuu/sni-each-converted huggingface dataset:
Context: Mutations and deletions of the NSD1 gene, located on chromosome 5q35, are responsible for over 90% of cases of Sotos syndrome. Fluorescent in situ hybridization analysis (FISH), MLPA or multiplex quantitative PCR allow detection of total/partial NSD1 deletions and direct sequencing allows detection of NSD1 mutations. We describe two boys with Sotos syndrome in whom PCR amplification and direct sequencing of the NSD1 gene identified two novel mutations not previously described: c.4736dupG in exon 12 and c.3938_3939insT in exon 7. In addition to the cardinal and major features of the syndrome (abnormal facial appearance, overgrowth, cardiac anomalies, renal anomalies, hypotonia, neonatal jaundice, seizures and brain MRI abnormalities) in both patients, one boy also had cryptorchidism and vertebral anomalies, features considered not common. Despite the wide range of possible combinations of phenotypic features, molecular analysis can correctly identify Sotos syndrome. 
 Question: Which gene is responsible for the development of Sotos syndrome?
Output: nsd1 gene
Context: The Song of the Gargoyle is a 1991 book for young readers by Zilpha Keatley Snyder. 
 Question: Who wrote the Song of the Gargoyle?
Output: zilpha keatley snyder
Context: Ultrasound is sound that has a wave frequency higher than the human ear can detect. It includes all sound with wave frequencies higher than 20,000 waves per second, or 20,000 hertz (Hz). Although we cant hear ultrasound, it is very useful to humans and some other animals. Uses of ultrasound include echolocation, sonar, and ultrasonography. Animals such as bats and dolphins send out ultrasound waves and use their echoes, or reflected waves, to identify the locations of objects they cannot see. This is called echolocation. Animals use echolocation to find prey and avoid running into objects in the dark. You can see in the Figure 1.1 how a bat uses echolocation to find insect prey. Sonar uses ultrasound in a way that is similar to echolocation. Sonar stands for sound navigation and ranging. It is used to locate underwater objects such as submarines. Thats how the ship pictured in the Figure 1.2 is using it. A sonar device is both a sender and a receiver. It sends out ultrasound waves and detects the waves after they reflect from underwater objects. The distance to underwater objects can be calculated from the known speed of sound in water and the time it takes for the sound waves to travel to the object. The equation for distance traveled when speed and time are known is: Distance = Speed Time Consider the ship and submarine pictured in the Figure 1.2. If an ultrasound wave travels from the ship to the submarine and back again in 2 seconds, what is the distance from the ship to the submarine? The sound wave travels from the ship to the submarine in just 1 second, or half the time it takes to make the round trip. The speed of sound waves through ocean water is 1437 m/s. Therefore, the distance from the ship to the submarine is: Q: Now assume that the sonar device on the ship sends an ultrasound wave to the bottom of the water. If the sound wave is reflected back to the device in 4 seconds, how deep is the water? A: The time it takes the wave to reach the bottom is 2 seconds. So the distance from the ship to the bottom of the water is: Distance = 1437 m/s 2 s = 2874 m Another use of ultrasound is to see inside the human body. This use of ultrasound is called ultrasonography. Harmless ultrasound waves are sent inside the body, and the reflected waves are used to create an image on a screen. This technology is used to examine internal organs and unborn babies without risk to the patient. You can see a doctor using ultrasound in the Figure 1.3. 
 Question: sonar is used to determine the
Output: distance to underwater objects.
Context: Panelefsiniakos B.C., or Paneleusian B.C., is a Greek professional basketball club that is located in Eleusis, Athens, Greece. 
 Question: What city was Panelefsiniakos B.C. formed in?
Output: eleusis
Context: 157640 Baumeler (2005 XS80) is an outer main-belt asteroid discovered on December 1, 2006 by Peter Kocher at the Observatory Naef Ependes in Switzerland. 
 Question: Who was behind the discovery of 157640 Baumeler?
Output: peter kocher
Context: In the United States Federal Budget for 2010, entitled 'A New Era of Responsibility', the DHS was allocated a discretionary budget of $42.7 billion . The end-of-yearDHS Annual Financial Report for financial year 2010 showed a net cost of operations of $56.4 billion , out of total budgetary resources of $83.2 billion . The components with the highest net cost were US Coast Guard , U.S. Customs and Border Protection , and Federal Emergency Management Agency . Revenues of $10.4 billion were generated in the year . According to the Washington Post, "DHS has given $31 billion in grants since 2003 to state and local governments for homeland security and to improve their ability to find and protect against terrorists, including $3.8 billion in 2010." 
 Question: Who recieved the most resources from the DHS, the US Coast Guard or State and Local governments?
Output: us coast guard
Context: When I was a kid, I always used to wonder how in the world my father work outside in the winter without a coat. It could be minus 20 degrees centigrade and there'd be Dad, removing snow, or perhaps chopping some wood --- his coat thrown aside--- wearing a shirt , a cap, and a pair of gloves. "Aren't you cold, Dad?" I'd ask. "No," Dad would reply. "I'm not cold--- working too hard to be cold." Many times I wondered whether my father was an extremely tough man, or whether he was foolish. One time when I was quite young, perhaps five or so, I went ice fishing with Dad. It was a bright, clear day--and bitterly cold. After we'd been out on the ice for a little while, my feet started getting cold. "Daddy, my feet are cold." I said. "Yeah, it's cold out here today," he replied. "Tell you what," he said. "Walk around. Make some circles in the snow. See how many different patterns you can make. That will get your feet warm." Now, I was just a little girl at the time but I remember thinking, "How in the world will walking around in the snow make my feet warm? Dad must be out of mind. But he was my father, after all. I made circles in the snow. I made squares. Pretty soon I was having so much fun making patterns in the snow. I forgot about my feet being cold. Now, all these years later, I know, too, from personal experience how my father was able to take his coat off and work outside in the winter wearing just a shirt, a cap and gloves. Because I do it, too. "Aren't you cold?" my husband asked one winter day. "No," I replied. "I'm not cold--working too hard to be cold." I hope my husband has decided I'm both tough and smart. But I guess quite a bit of the time he thinks I'm foolish. Wherever Dad is in that great big farm in the sky--I'm sure he can't help but smile whenever I take my coat off while I'm working outside in the winter. 
 Question: What might the author's husband think of her?
Output: foolish
Context: Parkinson's disease (PD) and dementia with Lewy bodies are common disorders of the aging population and characterized by the progressive accumulation of -synuclein (-syn) in the central nervous system. Aggregation of -syn into oligomers with a ring-like appearance has been proposed to play a role in toxicity. However, the molecular mechanisms and the potential sequence of events involved in the formation of pore-like structures are unclear. We utilized computer modeling and cell-based studies to investigate the process of oligomerization of wild-type and A53T mutant -syn in membranes. The studies suggest that -syn penetrates the membrane rapidly, changing its conformation from -helical towards a coiled structure. This penetration facilitates the incorporation of additional -syn monomers in the complex, and the subsequent displacement of phospholipids and the formation of oligomers in the membrane. This process occurred more rapidly, and with a more favorable energy of interaction, for mutant A53T compared with wild-type -syn. After 4 ns of simulation of the protein-membrane model, -syn had penetrated through two-thirds of the membrane. By 9 ns, the penetration of the annular -syn oligomers can result in the formation of pore-like structures that fully perforate the lipid bilayer. Experimental incubation of recombinant -syn in synthetic membranes resulted in the formation of similar pore-like complexes. Moreover, mutant (A53T) -syn had a greater tendency to accumulate in neuronal membrane fractions in cell cultures, resulting in greater neuronal permeability, as demonstrated with the calcein efflux assay. These studies provide a sequential molecular explanation for the process of -syn oligomerization in the membrane, and support the role of formation of pore-like structures in the pathogenesis of the neurodegenerative process in PD. 
 Question: Which disease of the central nervous system is characterized by the presence of Lewy bodies?
Output: parkinson's disease (pd)
Context: Street Dogs are an American punk rock band from Boston, MA, formed in 2002 by former Dropkick Murphys singer Mike McColgan. 
 Question: In what year did Street Dogs originate?
Output: 2002
Context: To characterize the patient demographics, clinical features, and antibiotic susceptibility of ocular infections caused by methicillin-resistant Staphylococcus aureus (MRSA), including community-associated (CA) and healthcare-associated (HA) isolates. Retrospective, observational study. Patients (n = 519) with culture-proven S. aureus ocular infections seen between January 1, 1999, and December 31, 2008, in Chang Gung Memorial Hospital. Data collected included patient demographics and clinical information. Antibiotic susceptibility was verified by disc diffusion method. Proportion of MRSA in S. aureus ocular infections and the clinical characteristics, diagnoses, and antibiotic susceptibility patterns of CA-MRSA versus HA-MRSA ocular infections. We identified 274 patients with MRSA ocular infections, which comprised 181 CA-MRSA and 93 HA-MRSA isolates. The average rate of MRSA in S. aureus infections was 52.8% with a stable trend, whereas the annual ratio of CA-MRSA in ocular MRSA infections averaged 66.1% and tended to increase over the 10-year interval. Patients with ocular CA-MRSA were younger. Lid and lacrimal system disorders were more common, but keratitis, endophthalmitis, and wound infection were less common among CA-MRSA cases than HA-MRSA cases. Both CA-MRSA and HA-MRSA isolates were resistant to clindamycin and erythromycin, but CA-MRSA was more susceptible to sulfamethoxazole/trimethoprim. Community-associated MRSA is an important pathogen of ocular infections; CA-MRSA and HA-MRSA ocular infections differ demographically and clinically, but both strains were multi-resistant in Chang Gung Memorial Hospital, one of the biggest referral centers in Taiwan. In a country with a high prevalence of MRSA, ophthalmologists should be aware of such epidemiologic information. 
 Question: What is MRSA?
Output: mrsa
Context: To characterize the patient demographics, clinical features, and antibiotic susceptibility of ocular infections caused by methicillin-resistant Staphylococcus aureus (MRSA), including community-associated (CA) and healthcare-associated (HA) isolates. Retrospective, observational study. Patients (n = 519) with culture-proven S. aureus ocular infections seen between January 1, 1999, and December 31, 2008, in Chang Gung Memorial Hospital. Data collected included patient demographics and clinical information. Antibiotic susceptibility was verified by disc diffusion method. Proportion of MRSA in S. aureus ocular infections and the clinical characteristics, diagnoses, and antibiotic susceptibility patterns of CA-MRSA versus HA-MRSA ocular infections. We identified 274 patients with MRSA ocular infections, which comprised 181 CA-MRSA and 93 HA-MRSA isolates. The average rate of MRSA in S. aureus infections was 52.8% with a stable trend, whereas the annual ratio of CA-MRSA in ocular MRSA infections averaged 66.1% and tended to increase over the 10-year interval. Patients with ocular CA-MRSA were younger. Lid and lacrimal system disorders were more common, but keratitis, endophthalmitis, and wound infection were less common among CA-MRSA cases than HA-MRSA cases. Both CA-MRSA and HA-MRSA isolates were resistant to clindamycin and erythromycin, but CA-MRSA was more susceptible to sulfamethoxazole/trimethoprim. Community-associated MRSA is an important pathogen of ocular infections; CA-MRSA and HA-MRSA ocular infections differ demographically and clinically, but both strains were multi-resistant in Chang Gung Memorial Hospital, one of the biggest referral centers in Taiwan. In a country with a high prevalence of MRSA, ophthalmologists should be aware of such epidemiologic information. 
 Question: What is MRSA?
Output: methicillin-resistant s. aureus
Context: The circumsporozoite protein (CS protein) on the malaria parasites in mosquitoes plays an important role in sporogony in mosquitoes. The RTS,S/AS01 malaria vaccine candidate, which has shown significant efficacy against clinical malaria in a large Phase 3 trial, targets the Plasmodium falciparum CS protein, but the ability of serum from vaccinated individuals to inhibit sporogony in mosquitoes has not been evaluated. Previously a double-blind, randomized trial of RTS,S/AS01 vaccine, as compared with rabies vaccine, in five- to 17-month old children in Tanzania was conducted. In this study, polyclonal human antibodies were purified from the pools of sera taken one month after the third vaccination. IgGs were purified from four pools of sera from 25 RTS,S/AS01 vaccinated children each, and two pools of sera from 25 children vaccinated with rabies vaccine each. The ability of antibodies to inhibit P. falciparum oocyst formation and/or sporogony in the mosquito host was evaluated by a standard membrane-feeding assay. The test antibodies were fed on day 0 (at the same time as the gametocyte feed), or on days 3 or 6 (serial-feed experiments). The oocyst and sporozoite counts were performed on days 8 and 16, respectively. In addition, two human anti-CS monoclonal antibodies (mAb) and a control mAb were also evaluated. Polyclonal anti-CS IgG preparations from RTS,S-vaccinated children tested at concentrations of 149-210 ELISA units (EU)/ml did not show significant inhibition in oocyst and sporozoite formation when the antibodies were fed with gametocytes at the same time, or later (serial-feed experiments). Similarly, anti-CS mAbs tested at 6,421 or 7,122 EU/ml did not show reduction in oocyst and sporozoite formation. This study does not support the concept that anti-CS antibodies induced by the RTS,S/AS01 vaccines in humans noticeably reduce malaria transmission by blocking P. falciparum sporozoite development or salivary gland invasion in mosquitoes when taken up during feeding. 
 Question: RTS S AS01 vaccine was developed to prevent which disease?
Output: malaria
Context: The Texans' ninth match was an AFC South rivalry match against the Jaguars at EverBank Field. In the first quarter the Texans trailed early as kicker Josh Scobee hit a 38-yard field goal. They replied after kicker Neil Rackers made a 24-yard field goal. They trailed again in the 2nd quarter with RB Maurice Jones-Drew getting a 3 and a 9-yard TD run. However, the lead didn't last long after RB Arian Foster got a 1-yard TD run, and QB Matt Schaub threw a 9-yard TD pass to WR Andre Johnson. The Jaguars stayed in the lead when QB David Garrard completed a 52-yard TD pass to TE Zach Miller, but the Texans replied again with Schaub finding WR Kevin Walter on an 18-yard TD pass. Suddenly, the Texans' defense broke through with only a few seconds remaining after Garrard made a 50-yard TD pass to WR Mike Thomas. The ball was batted into his hands by Texans Defensive back Glover Quin, who made an attempt to bat the ball to the ground. 
 Question: Which kicker's first quarter field goal was shorter?
Output: neil rackers
Context: Sleep disorders are frequent comorbidities in neurologic patients. This review focuses on clinical aspects and prognosis of 3 neurologic sleep disorders: narcolepsy, restless legs syndrome/Willis-Ekbom disease (RLS/WED), and REM sleep behavior disorder (RBD). Narcolepsy causes pervasive, enduring excessive daytime sleepiness, adversely affecting patients' daily functioning. RLS/WED is characterized by an uncomfortable urge to move the legs before sleep, often evolving toward augmentation and resulting in daylong bothersome symptoms. RBD causes potentially injurious dream enactment behaviors that often signify future evolution of overt synucleinopathy neurodegeneration in as many as 81% of patients. Timely recognition, referral for polysomnography, and longitudinal follow-up of narcolepsy, RLS/WED, and RBD patients are imperatives for neurologists in providing quality comprehensive patient care. 
 Question: Willis-Ekbom disease is also known as?
Output: restless legs syndrome
Context: A personal journey into the heart of the Killing FieldsOne of the most harrowing and compelling personal documentaries of our time, ENEMIES OF THE PEOPLE exposes for the first time the truth about the Killing Fields and the Khmer Rouge who were behind Cambodias horrific genocide. More than simply an inquiry into Cambodias experience, however, ENEMIES OF THE PEOPLE is a profound meditation on the nature of good and evil, shedding light on the capacity of some people to do terrible things and for others to forgive them.Winner of a dozen top documentary festival awards, including a Special Jury Prize at Sundance and the Grand Jury Award at the Full Frame Documentary Festival, this is a riveting film that takes audiences as close to witnessing evil as they are ever likely to get. It is also a personal journey into the heart of darkness by journalist/filmmaker Thet Sambath, whose family was wiped out in the Killing Fields, but whose patience and discipline elicits unprecedented on-camera confessions from perpetrators at all levels of the Khmer Rouge hierarchy. This is investigative journalism of the highest order.In 1974, Thet Sambaths father became one of the nearly two million people who were murdered by the Khmer Rouge when he refused to give them his buffalo. Sambaths mother was forced to marry a Khmer Rouge militiaman and died in childbirth in 1976, while his eldest brother disappeared in 1977. Sambath himself escaped Cambodia at age 10 when the Khmer Rouge fell in 1979.Fast forward to 1998, and Sambath, now a journalist, got to know the children of some senior Khmer Rouge cadre and gradually earned their trust. Then, for a decade, he spent weekends visiting the home of the most senior surviving leader, Nuon Chea, aka Brother Number Two under Pol Pot. But he never used to say anything different from what he told Western journalists, says Sambath, I was low-ranking, I knew nothing, I am not a killer. Then one day he said to me Sambath, I trust you, you are the person I would like to tell my story to. Ask me what you want to know. For the next five years he told me the truth, as he saw it, including all the details of killing.Sambath also won the confidence of lower-level Khmer Rouge soldiers, now ordinary fathers and grandfathers, who demonstrated to him how they slit peoples throats. For these murderers, it was the first time they admitted what they had done. He taped their interactions and discussions about the killings, and together with British documentarian Rob Lemkin they created this landmark film.For Sambath, it has been an ongoing, lifelong personal journey to discover what was behind such horror; he neglected both his family and his own happiness in the search for truth with hope of reconciliation. ENEMIES OF THE PEOPLE is at once a cinematically beautiful, chillingly insightful, and deeply personal piece of documentary filmmaking. 
 Question: What year does Thet Sambath seek confessions and explanations?
Output: 1998
Context: Cell-mediated immunity plays a crucial role in the control of many infectious diseases, necessitating the need for adjuvants that can augment cellular immune responses elicited by vaccines. It is well established that protection against one such disease, malaria, requires strong CD8(+) T cell responses targeted against the liver stages of the causative agent, Plasmodium spp. In this report we show that the dendritic cell-specific chemokine, dendritic cell-derived CC chemokine 1 (DC-CK1), which is produced in humans and acts on naive lymphocytes, can enhance Ag-specific CD8(+) T cell responses when coadministered with either irradiated Plasmodium yoelii sporozoites or a recombinant adenovirus expressing the P. yoelii circumsporozoite protein in mice. We further show that these enhanced T cell responses result in increased protection to malaria in immunized mice challenged with live P. yoelii sporozoites, revealing an adjuvant activity for DC-CK1. DC-CK1 appears to act preferentially on naive mouse lymphocytes, and its adjuvant effect requires IL-12, but not IFN-gamma or CD40. Overall, our results show for the first time an in vivo role for DC-CK1 in the establishment of primary T cell responses and indicate the potential of this chemokine as an adjuvant for vaccines against malaria as well as other diseases in which cellular immune responses are important. 
 Question: Which is the causative agent of malaria?
Output: plasmodium species
Context: Cell-mediated immunity plays a crucial role in the control of many infectious diseases, necessitating the need for adjuvants that can augment cellular immune responses elicited by vaccines. It is well established that protection against one such disease, malaria, requires strong CD8(+) T cell responses targeted against the liver stages of the causative agent, Plasmodium spp. In this report we show that the dendritic cell-specific chemokine, dendritic cell-derived CC chemokine 1 (DC-CK1), which is produced in humans and acts on naive lymphocytes, can enhance Ag-specific CD8(+) T cell responses when coadministered with either irradiated Plasmodium yoelii sporozoites or a recombinant adenovirus expressing the P. yoelii circumsporozoite protein in mice. We further show that these enhanced T cell responses result in increased protection to malaria in immunized mice challenged with live P. yoelii sporozoites, revealing an adjuvant activity for DC-CK1. DC-CK1 appears to act preferentially on naive mouse lymphocytes, and its adjuvant effect requires IL-12, but not IFN-gamma or CD40. Overall, our results show for the first time an in vivo role for DC-CK1 in the establishment of primary T cell responses and indicate the potential of this chemokine as an adjuvant for vaccines against malaria as well as other diseases in which cellular immune responses are important. 
 Question: Which is the causative agent of malaria?
Output: plasmodium spp.
Context: Rodora is a 1956 movie from Sampaguita Pictures about a man (Juancho Gutierrez) who falls in love with a girl (Amalia Fuentes). 
 Question: The distributor of Rodora was whom?
Output: sampaguita pictures
Context: The classic form of Ehlers-Danlos syndrome (cEDS) is an inherited connective tissue disorder, where mutations in type V collagen-encoding genes result in abnormal collagen fibrils. Thus the cEDS patients have pathological connective tissue morphology and low stiffness, but the rate of connective tissue protein turnover is unknown. We investigated whether cEDS affected the protein synthesis rate in skin and tendon, and whether this could be stimulated in tendon tissue with insulin-like growth factor-I (IGF-I). Five patients with cEDS and 10 healthy, matched controls (CTRL) were included. One patellar tendon of each participant was injected with 0.1 ml IGF-I (Increlex, Ipsen, 10 mg/ml) and the contralateral tendon with 0.1 ml isotonic saline as control. The injections were performed at both 24 and 6 h prior to tissue sampling. The fractional synthesis rate (FSR) of proteins in skin and tendon was measured with the stable isotope technique using a flood-primed continuous infusion over 6 h. After the infusion one skin biopsy and two tendon biopsies (one from each patellar tendon) were obtained. We found similar baseline FSR values in skin and tendon in the cEDS patients and controls [skin: 0.005 0.002 (cEDS) and 0.007 0.002 (CTRL); tendon: 0.008 0.001 (cEDS) and 0.009 0.002 (CTRL) %/h, mean SE]. IGF-I injections significantly increased FSR values in cEDS patients but not in controls (delta values: cEDS 0.007 0.002, CTRL 0.001 0.001%/h). In conclusion, baseline protein synthesis rates in connective tissue appeared normal in cEDS patients, and the patients responded with an increased tendon protein synthesis rate to IGF-I injections. 
 Question: What tissue is most affected in Ehlers-Danlos syndromes?
Output: connective tissue
Context: The structure of Mont Pelerin TV Tower, whose foundations are 1075 meters above sea level, weighs 13000 tons and consists of 7500 cubic metres of concrete. 
 Question: What is the surface of Mont Pelerin TV Tower made of?
Output: concrete
Context: The smallest front of the war was in Catalonia. In 1689 the Duke of Noailles had led French forces there aimed at bringing further pressure to bear on the Spanish by re-igniting a peasant rising against Charles II, which initially broke out in 1687. Exploiting the situation, Noailles captured Camprodon on 22 May, but a larger Spanish army under the Duke of Villahermosa forced him to withdraw back to Roussillon in August. The Catalan campaign settled down in 1690, but a new front in Piedmont-Savoy proved more eventful. A ferment of religious animosities and Savoyard hatred of the French produced a theatre characterised by massacres and atrocities: constant guerrilla attacks by the armed populace were met by draconian reprisals. In 1690 Saint-Ruth took most of the Victor Amadeus II's exposed Duchy of Savoy, routing the Savoyard army in the process until only the great fortress of Montmelian remained in ducal hands; while to the south in Piedmont, Nicolas Catinat led 12,000 men and soundly defeated Victor Amadeus at the Battle of Staffarda on 18 August. Catinat immediately took Saluzzo, followed by Savigliano, Fossano, and Susa, but lacking sufficient troops, and with sickness rife within his army, Catinat was obliged to withdraw back across the Alps for the winter. 
 Question: What happened first: Catalan campaign settled down or the Battle of Staffarda?
Output: catalan campaign settled down
Context: As of the census of 2000, there were 218,590 people, 79,667 households, and 60,387 families residing in the county. The population density was 496 people per square mile (192/km). There were 83,146 housing units at an average density of 189 per square mile (73/km). The racial makeup of the county was 86.77% Race (United States Census), 9.27% Race (United States Census), 0.23% Race (United States Census), 1.52% Race (United States Census), 0.06% Race (United States Census), 0.69% from Race (United States Census), and 1.47% from two or more races. 1.91% of the population were Race (United States Census) or Race (United States Census) of any race. 22.5% were of German people, 13.1% Irish people, 9.8% Italian people, 9.2% English, 8.1% "American" and 6.0% Polish ancestry. 
 Question: Which ancestral group is larger: German or Irish?
Output: german
Context: Deep brain stimulation (DBS) is the technique of neurostimulation of deep brain structures for the treatment of conditions such as essential tremor, dystonia, Parkinson's disease and chronic pain syndromes. The procedure uses implanted deep brain stimulation electrodes connected to extension leads and an implantable pulse generator (IPG). Hardware failure related to the DBS procedure is not infrequent, and includes electrode migration and disconnection. We describe a patient who received bilateral globus pallidus internus DBS for dystonia with initially good clinical response, but the device eventually failed. Radiographs showed multiple twisting of the extension leads with disconnection from the brain electrodes and a diagnosis of Twiddler's syndrome was made. Twiddler's syndrome was first described in patients with cardiac pacemakers. Patients with mental disability, elderly and obese patients are at increased risk. Twiddler's syndrome should be suspected whenever there is a failure of the DBS device to relieve symptoms previously responsive to stimulation. Surgical correction is usually required. 
 Question: Neurostimulation of which nucleus is used for treatment of dystonia?
Output: globus pallidus internus
Context: The Narym River is a river in the Eastern Kazakhstan, a tributary of the Irtysh River, originating at the junction of the ridges Narym and Sarymsakty of wetland formed by the mountain runoff streams. 
 Question: The body of water that Narym River is near is what?
Output: irtysh river
Context: Most people today think of chocolate as something sweet to eat or drink and can be easily found in stores around the world. It might surprise you that chocolate was once highly treasured. The wealthy people of Spain first enjoyed a sweetened chocolate drink. Later, the popularity of the drink spread throughout Europe. Chocolate remained a drink that only wealthy people could afford to drink until the eighteenth century. During the period known as the Industrial Revolution, new technologies helped make chocolate less costly to produce. Farmers grow cacao trees in many countries in Africa, Central and South America, but these trees are difficult to grow. They require an exact amount of water, warmth, soil and protection. After about five years, cacao trees start producing large fruits called pods, which grow near the trunk of the tree. The seeds inside these pods are harvested to make chocolate. Growing cacao is very hard work for farmers. Today, chocolate industry officials, activists, and scientists are working with farmers. They are trying to make sure that cacao can be grown in a way that is easy for the farmers and safe for the environment. The market value of the yearly cacao crop around the world is more than five billion dollars. Chocolate is especially popular in Europe and the United States. Each year, Americans eat an average of more than 5 kilograms of chocolate per person. Specialty shops that sell costly chocolate are also very popular. Many offer chocolate lovers the chance to taste chocolate grown in different areas of the world. 
 Question: What made it possible to produce chocolate inexpensively?
Output: new technologies.
Context: Rahmat-un-Nisa (1620 -- October/November 1691), better known by her title Nawab Bai, was the second wife of the Mughal Emperor Aurangzeb. 
 Question: What is Nawab Bai's spouse's name?
Output: aurangzeb
Context: The Pistolet modele An XIII was a flintlock cavalry pistol, in service in French units from 1806. 
 Question: What year was Pistolet modele An XIII made?
Output: 1806
Context: Marino finished the game with 29 out of 50 pass completions for 318 yards, 1 touchdown, and 2 interceptions. Clayton was the top receiver of the game, with 6 receptions for 92 yards. Walker returned 4 kickoffs for 93 yards and gained 15 yards on 2 punt returns. Nathan was the Dolphins leading rusher with 18 yards, while also catching 10 passes for 83 yards. Craig had 58 rushing yards, 77 receiving yards, and 3 touchdowns. He was the first player ever to score 3 touchdowns in a Super Bowl, and his 2 touchdown catches also tied a Super Bowl record. Tyler led San Francisco in rushing with 65 yards, and also caught 4 passes for 70 yards. Clark caught 6 passes for 77 yards. Board recorded 2 sacks. McLemore recorded 51 punt return yards, the second most in Super Bowl history. Sports Illustrated called 49ers defensive tackle Gary Johnson (American football) the Super Bowls "unofficial defensive MVP" after he recorded one sack, flushed Marino out of the passing pocket numerous times, and had four unassisted tackles. 
 Question: Which player had the most rushing yards?
Output: tyler
Context: Hoping to break their current losing streak the Cardinals flew to Arrowhead Stadium for an interconference duel with the Chiefs. The Cardinals scored with kicker Jay Feely hitting a 36-yard field goal, but they fell behind with QB Matt Cassel completing a 1-yard TD pass to WR Dwayne Bowe. This was followed by RB Thomas Jones getting a 1 and a 3-yard TD run. The Cardinals responded with Feely making a 29-yard field goal, but they struggled further with kicker Ryan Succop getting a 23-yard field goal, followed by Cassel throwing a 38-yard TD pass to Bowe. The Cardinals cut the lead with QB Derek Anderson completing a 3-yard TD pass to WR Larry Fitzgerald. 
 Question: What team scored the first touchdown of the game?
Output: chiefs
Context: In week 12, the Lions flew east for another battle of division leaders, this time with the AFC East's 8-2 New England Patriots. The Lions failed to score a touchdown for the second consecutive week, and fell to second place after a blowout loss. The Lions scored first when Matt Prater hit a 48-yard field goal in the first quarter. The Patriots then took the lead which they kept for the rest of the game when Tim Wright caught a 4-yard touchdown pass from Tom Brady near the end of the first quarter. The Lions responded with a 20-yard field goal in the second quarter. The Patriots then scored two touchdowns on a 3-yard run from LeGarrette Blount, then an 8-yard catch by Tim Wright. New England's Stephen Gostkowski then kicked a 35-yard field goal to make the score 24-6 at halftime. The only score of the third quarter was a Patriots 35 yard field goal. In the final quarter, the Lions scored their third field goal, this one from 49 yards out. The Patriots capped their large victory with a 1-yard touchdown run from LeGarrette Blount. 
 Question: Who scored the only points of the third quarter?
Output: patriots
Context: It is estimated that some seven hundred million people, about half the world's adult population, are unable to read or write, and there are probably two hundred and fifty million more whose level is so slight that it is hardly called literacy . Recently the attack on illiteracy had been stepped up. A world plan has been drawn up by a committee of UNESCO experts in Paris, as part of the United Nations Development Decade ,and an international conference of the subject has also been held. UNESCO stresses that functional literacy is the aim. People must learn the basic skills of responsible citizenship, the ability of reading notices, newspapers, timetables, letters, price-lists to keep simple records and accounts, to select the importance of the information gathered, and to fill in the forms. The major areas of illiteracy are in Asia, Africa, and Central and South America. In Africa there are at least one hundred million illiterate people, which is eighty to eighty-five percent of the total population. In Europe the figure is about twenty-four million; most of them are in Sothern Europe, with Spain, Italy, Portugal, Yugoslavia heading the list (the United Kingdom has about seven hundred thousand). UNESGO is eager for each country in the world, poor or rich, to wipe out illiteracy. 
 Question: Which of the statements is true?
Output: the major areas of illiteracy are in asia, africa, and central and south america.
Context: News @ 6 is the flagship evening newscast of People's Television Network in the Philippines, succeeding newscast Teledyaryo. 
 Question: What is the country News @ 6 is from?
Output: philippines
Context: The protein alpha-synuclein (ASYN) is thought to be involved in the development of dementia with Lewy bodies (DLB). Overexpression of ASYN has been linked to cellular toxicity and human disease, and in experimental models, chaperones such as heat shock proteins (HSPs) are protective against ASYN toxicity. We have assessed the abundance of mRNA for ASYN and chaperones and the abundance and solubility of the encoded proteins in temporal cortex from sporadic human DLB. We found a reduction of ASYN mRNA in DLB (44.9% of control). The abundance of the Triton-soluble fraction (bioavailable protein) was not altered, but there was an increase of the Triton-insoluble component (likely representing aggregates). We evaluated 3 chaperones: HSP70, HSP90, and HDJ1. HSP70 mRNA was increased in DLB, whereas the mRNAs for HSP90 and HDJ1 were unchanged. HSP70 accumulated in the Triton-soluble fraction, whereas HSP90 and HDJ1 proteins accumulated in the Triton-insoluble fraction. These observations suggest that sporadic DLB is not associated with overexpression of ASYN. Rather, the persistence of normal soluble ASYN protein levels, despite the reduction of its mRNA, suggests a primary defect in clearance of the protein. However, this reduced clearance cannot be attributed to a failure of chaperone expression, because their mRNA is unchanged or increased in the DLB brain. 
 Question: Which is the primary protein component of Lewy bodies?
Output: αsyn
Context: The protein alpha-synuclein (ASYN) is thought to be involved in the development of dementia with Lewy bodies (DLB). Overexpression of ASYN has been linked to cellular toxicity and human disease, and in experimental models, chaperones such as heat shock proteins (HSPs) are protective against ASYN toxicity. We have assessed the abundance of mRNA for ASYN and chaperones and the abundance and solubility of the encoded proteins in temporal cortex from sporadic human DLB. We found a reduction of ASYN mRNA in DLB (44.9% of control). The abundance of the Triton-soluble fraction (bioavailable protein) was not altered, but there was an increase of the Triton-insoluble component (likely representing aggregates). We evaluated 3 chaperones: HSP70, HSP90, and HDJ1. HSP70 mRNA was increased in DLB, whereas the mRNAs for HSP90 and HDJ1 were unchanged. HSP70 accumulated in the Triton-soluble fraction, whereas HSP90 and HDJ1 proteins accumulated in the Triton-insoluble fraction. These observations suggest that sporadic DLB is not associated with overexpression of ASYN. Rather, the persistence of normal soluble ASYN protein levels, despite the reduction of its mRNA, suggests a primary defect in clearance of the protein. However, this reduced clearance cannot be attributed to a failure of chaperone expression, because their mRNA is unchanged or increased in the DLB brain. 
 Question: Which is the primary protein component of Lewy bodies?
Output: α-synuclein
Context: The protein alpha-synuclein (ASYN) is thought to be involved in the development of dementia with Lewy bodies (DLB). Overexpression of ASYN has been linked to cellular toxicity and human disease, and in experimental models, chaperones such as heat shock proteins (HSPs) are protective against ASYN toxicity. We have assessed the abundance of mRNA for ASYN and chaperones and the abundance and solubility of the encoded proteins in temporal cortex from sporadic human DLB. We found a reduction of ASYN mRNA in DLB (44.9% of control). The abundance of the Triton-soluble fraction (bioavailable protein) was not altered, but there was an increase of the Triton-insoluble component (likely representing aggregates). We evaluated 3 chaperones: HSP70, HSP90, and HDJ1. HSP70 mRNA was increased in DLB, whereas the mRNAs for HSP90 and HDJ1 were unchanged. HSP70 accumulated in the Triton-soluble fraction, whereas HSP90 and HDJ1 proteins accumulated in the Triton-insoluble fraction. These observations suggest that sporadic DLB is not associated with overexpression of ASYN. Rather, the persistence of normal soluble ASYN protein levels, despite the reduction of its mRNA, suggests a primary defect in clearance of the protein. However, this reduced clearance cannot be attributed to a failure of chaperone expression, because their mRNA is unchanged or increased in the DLB brain. 
 Question: Which is the primary protein component of Lewy bodies?
Output: alpha-synuclein
Context: The film was broadcast in 2004 on Indus TV Network in Pakistan & UAE and in 2005 on Zee TV UK & USA as part of film series 'Maa Aur Mamta', which consists of 13 films including Meharun Nisa. 
 Question: What was the year of Meharun Nisa?
Output: 2004
Context: Zombie cited American horror films The Texas Chain Saw Massacre (1974) and The Hills Have Eyes (1977) as influences on House of 1000 Corpses, as well as other films released during the 1970s. 
 Question: Which place is House of 1000 Corpses in?
Output: texas
Context: As the film begins, Daisy Duck is talking to a psychiatrist about an incident that occurred with her boyfriend, Donald. She recalls how they were walking through the park, passing by a skyscraper. On the 99th floor of the skyscraper is a potted flower, which falls and hits Donald on the head, knocking him out. When he comes to, he hears a voice in his head, telling him, "You are the greatest singer in the world." He gets up, and proceeds to croon "When You Wish upon a Star" in a Sinatra-like voice. Daisy is stunned, but Donald coldly glances at her as though he does not recognize her. At that moment, a theatrical agent sweeps Donald into his window, causing the flower on his head to fall at Daisy's feet.She takes the flower home, as a way to remember her lost love. She sees Donald everywhere, hawking products and on marquees-- he has become a major celebrity. She almost drives herself insane, but eventually hears that Donald is playing at the Music City Radio Hall. She decides to go see him, but is greatly hindered by a massive crowd. Many months pass, during which Daisy has no success at being able to see Donald.One night, as she is going home, she runs into Donald on the street. She grovels at Donald's feet, but only succeeds in getting a dime thrown at her. She then comes back to the present, where she is talking to the psychiatrist about what happened. The psychiatrist concludes that the hit on the head from the flower pot is what caused Donald to change so radically. He offers to help, but warns her that Donald will no longer be successful if he changes back to normal. Daisy is eager to have him back, though, so the psychiatrist tells her to put the flower in another pot and drop it on Donald's head somehow. She agrees to this plan.That night, as Donald is performing, Daisy slips into the building through the back door. She makes her way past a sleeping security guard, and climbs up into the rafters, where she drops the pot on Donald. It hits him on the head, and he quickly reverts to his regular voice. He is booed off the stage and thrown out of the building, where Daisy is waiting for him. He is thrilled to see her, asking, "Where have you been?" They kiss as the film irises out. 
 Question: The dilemma the doctor offers daisy is for Donald to lose either her or what?
Output: donald will no longer be successful
Context: Successful people have developed habits leading to success. Those are the people you want to study and follow. Do what they do. Read what they read. If they are local, see if you can take them to lunch and ask questions. If not, get a hold of some of the things they have written about or listen to them. Most successful people enjoy the opportunity to coach people along and to help them become successful. It is their way of giving back. The trouble is that most people won't ask. They come up with excuses. They say to themselves, " I am not important enough for this person to talk to me." The successful people understand that life is a learning experience and it doesn't stop in school. They always strive( ,) to reach the next level. Life will always give you the results of your actions. Ask yourself what actions are you taking? What are you creating? You create what you think about. Willie Hooks calls it our h. a. b. e.'s. Our habits, attitudes, beliefs and expectations. Before starting any new habit we have to know what we want. So how do we permanently change our habits? Start your action plan. Put your plan together. What do I need to do first? Set my goals. Then next I would put a diet plan together. Then I would start an exercise program. You get the idea. Put a good solid plan together. So there it is in a nutshell. We have the power to change any bad habit that we don't like. Will it be easy? Probably not, but it might not be as hard as we think either. The hard part is to get started. Remember that these habit have been a part of us for a long time so don't expect miracles at first. Use the process described above and you cam overcome and change any habit that you want to change. 
 Question: What does h. a. b. e's stand for?
Output: habits, attitudes, beliefs and expectations.
Context: The Steelers stayed home for a 3-game home stand and for a Sunday Night duel against the Ravens. The Ravens scored first when Joe Flacco hooked up with Torrey Smith 35-yard TD pass to take a 7-0 lead for the only score of the first quarter. In the 2nd quarter, the Steelers managed to tie the game up when Ben Roethlisberger found Le'Veon Bell on a 5-yard TD pass for a 7-7 game. They eventually took the lead when Roethlisberger found Martavis Bryant on a 19-yard TD pass to make it a 14-7 game. The Ravens came within 4 as Justin Tucker kicked a 46-yard field goal to make it 14-10 game. However, the Steelers would manage to go ahead by 12 before halftime when Roethlisberger found Markus Wheaton on a 47-yard TD pass followed by a successful 2-point conversion for a 22-10 lead at halftime. After a scoreless 3rd quarter, the Steelers came out strong and went back to work in the 4th when Roethlisberger found Antonio Brown on a 54-yard TD pass making the score 29-10. The Ravens responded with a big play as Jacoby Jones ran a 108-yard kickoff return for a TD to make it a 29-17 game. Roethlisberger found Bryant again on an 18-yard TD pass to make the score 36-17. This was followed by the Ravens trying their hand at coming back when Flacco found Crockett Gillmore on a 1-yard TD pass (with a failed 2-point conversion) for a 36-23 score. But the Steelers were able to seal the game when Roethlisberger found Matt Spaeth on a 33-yard TD pass for a final score of 43-23. A week after passing for a franchise-record six touchdowns against Indianapolis, Roethlisberger duplicated the feat to lead Pittsburgh to its third consecutive win. The 12 touchdown passes over the last two games broke the NFL record of 11 set by Tom Flores for Oakland in the AFL in 1963 and matched by New England's Tom Brady in 2007. 
 Question: How many yards was the field goal in the second quarter?
Output: 46-yard
Context: English is an important global language, but that doesn't mean it's easy to learn. Many experts have tried to make English easier for students to learn--but they weren't always successful. In 1930, Professor CK Ogden of Cambridge University invented Basic English. It had only 850 words (and just eighteen verbs) and Ogden said most people could learn it in just thirty hours. The problem was that people who learned Basic English could write and say simple messages, but they couldn't understand the answers in "real" English! It was also impossible to explain a word if it wasn't in the Basic English word list. For example, if you wanted a watermelon, you asked for "a large green fruit with the form of an egg, which has a sweet red inside and a good taste"! RE Zachrisson, a university professor in Sweden, decided that the biggest problem for learners of English was spelling, so he invented a language called Anglic. Anglic was similar to English, but with much simpler spelling. "Father" became "faadher", "new" became "nue' and "years" became "yeerz". Unfortunately for some students of English, Anglic never became popular. Even easier is the language which ships' captains use: it's called "Seaspeak". Seaspeak uses a few simple phrases for every possible situation. In Seaspeak, for example, you don't say, "I'm sorry what did you say?" or "I didn't understand, can you repeat that?" It's just "Say again." No more grammar! In the age of international communication through the Internet who knows? ... a new form of English might appear. A large number of the world's e-mails are in English and include examples of "NetLingo" like OIC (Oh, I see) and TTYL (Talk to you later). In another fifty years, English might not exist ... we will probably all speak fluent Internetish! 
 Question: According to Professor Zachrisson, what was the biggest problem for learners of English?
Output: spelling.