niryuu/sni-each-converted huggingface dataset:
Context: Cancer cells frequently induce aberrant centrosomes, which have been implicated in cancer initiation and progression. Human colorectal cancer cells, HCT116, contain aberrant centrioles composed of disorganized cylindrical microtubules and displaced appendages. These cells also express unique centrosome-related structures associated with a subset of centrosomal components, including gamma-tubulin, centrin and PCM1. During hydroxyurea treatment, these abnormal structures become more abundant and undergo a change in shape from small dots to elongated fibers. Although gamma-tubulin seems to exist as a ring complex, the abnormal structures do not support microtubule nucleation. Several lines of evidence suggest that the fibers correspond to a disorganized form of centriolar microtubules. Plk4, a mammalian homolog of ZYG-1 essential for initiation of centriole biogenesis, is not associated with the gamma-tubulin-specific abnormal centrosomes. The amount of Plk4 at each centrosome was less in cells with abnormal centrosomes than cells without gamma-tubulin-specific abnormal centrosomes. In addition, the formation of abnormal structures was abolished by expression of exogenous Plk4, but not SAS6 and Cep135/Bld10p, which are downstream regulators required for the organization of nine-triplet microtubules. These results suggest that HCT116 cells fail to organize the ninefold symmetry of centrioles due to insufficient Plk4. 
 Question: Where in the cell do we find the protein Cep135?
Output: centrosome
Context: Jay Hawk Talk is the third studio album by trumpeter Carmell Jones. 
 Question: Which artist is Jay Hawk Talk co-written and recorded by?
Output: carmell jones
Context: As the film begins, Daisy Duck is talking to a psychiatrist about an incident that occurred with her boyfriend, Donald. She recalls how they were walking through the park, passing by a skyscraper. On the 99th floor of the skyscraper is a potted flower, which falls and hits Donald on the head, knocking him out. When he comes to, he hears a voice in his head, telling him, "You are the greatest singer in the world." He gets up, and proceeds to croon "When You Wish upon a Star" in a Sinatra-like voice. Daisy is stunned, but Donald coldly glances at her as though he does not recognize her. At that moment, a theatrical agent sweeps Donald into his window, causing the flower on his head to fall at Daisy's feet.She takes the flower home, as a way to remember her lost love. She sees Donald everywhere, hawking products and on marquees-- he has become a major celebrity. She almost drives herself insane, but eventually hears that Donald is playing at the Music City Radio Hall. She decides to go see him, but is greatly hindered by a massive crowd. Many months pass, during which Daisy has no success at being able to see Donald.One night, as she is going home, she runs into Donald on the street. She grovels at Donald's feet, but only succeeds in getting a dime thrown at her. She then comes back to the present, where she is talking to the psychiatrist about what happened. The psychiatrist concludes that the hit on the head from the flower pot is what caused Donald to change so radically. He offers to help, but warns her that Donald will no longer be successful if he changes back to normal. Daisy is eager to have him back, though, so the psychiatrist tells her to put the flower in another pot and drop it on Donald's head somehow. She agrees to this plan.That night, as Donald is performing, Daisy slips into the building through the back door. She makes her way past a sleeping security guard, and climbs up into the rafters, where she drops the pot on Donald. It hits him on the head, and he quickly reverts to his regular voice. He is booed off the stage and thrown out of the building, where Daisy is waiting for him. He is thrilled to see her, asking, "Where have you been?" They kiss as the film irises out. 
 Question: What fell on Donald's head?
Output: a flower pot
Context: Biologists agree that the ancestor of mitochondria was an alpha-proteobacterium. But there is no consensus as to what constitutes an alpha-proteobacterial gene. Is it a gene found in all or several alpha-proteobacteria, or in only one? Here, we examine the proportion of alpha-proteobacterial genes in alpha-proteobacterial genomes by means of sequence comparisons. We find that each alpha-proteobacterium harbours a particular collection of genes and that, depending upon the lineage examined, between 97 and 33% are alpha-proteobacterial by the nearest-neighbour criterion. Our findings bear upon attempts to reconstruct the mitochondrial ancestor and upon inferences concerning the collection of genes that the mitochondrial ancestor possessed at the time that it became an endosymbiont. 
 Question: Which species of bacteria did the mitochondria originate from?
Output: biologists agree that the ancestor of mitochondria was an alpha-proteobacterium.
Context: A case of mosaic Turner's syndrome with a 45,X/46,XX/47,XXX karyotype, who was also a fragile X obligate carrier as the mother of an affected boy, was identified by molecular diagnosis. Complete haplotyping and direct DNA analysis showed that the X chromosome in all metaphases was the normal X. At the age of 57, she is mentally normal. Her external appearance was typical of Turner's syndrome. This report shows that molecular studies in conjunction with cytogenetic analysis can help in the clinical diagnosis of a rare case and can show the uniqueness of a case such as the one here described. 
 Question: What chromosome is affected in Turner's syndrome?
Output: x
Context: Neurobiology of speech and language has previously been studied in the KE family, in which half of the members have severe impairment in both speech and language. The gene responsible for the phenotype was mapped to chromosome 7q31 and identified as the FOXP2 gene, coding for a transcription factor containing a polyglutamine tract and a forkhead DNA-binding domain. Because of linkage studies implicating 7q31 in autism, where language impairment is a component of the disorder, and in specific language impairment, FOXP2 has also been considered as a potential susceptibility locus for the language deficits in autism and/or specific language impairment. In this study, we characterized mice with a disruption in the murine Foxp2 gene. Disruption of both copies of the Foxp2 gene caused severe motor impairment, premature death, and an absence of ultrasonic vocalizations that are elicited when pups are removed from their mothers. Disruption of a single copy of the gene led to modest developmental delay but a significant alteration in ultrasonic vocalization in response to such separation. Learning and memory appear normal in the heterozygous animals. Cerebellar abnormalities were observed in mice with disruptions in Foxp2, with Purkinje cells particularly affected. Our findings support a role for Foxp2 in cerebellar development and in a developmental process that subsumes social communication functions in diverse organisms. 
 Question: Which gene is responsible for proper speech development?
Output: foxp2
Context: Chaperone-mediated autophagy is one of several lysosomal pathways of proteolysis. This pathway is activated by physiological stresses such as prolonged starvation. Cytosolic proteins with particular peptide sequence motifs are recognized by a complex of molecular chaperones and delivered to lysosomes. No vesicular traffic is required for this protein degradation pathway, so it differs from microautophagy and macroautophagy. Protein substrates bind to a receptor in the lysosomal membrane, the lysosome-associated membrane protein (lamp) type 2a. Levels of lamp2a in the lysosomal membrane are controlled by alterations in the lamp2a half-life as well as by the dynamic distribution of the protein between the lysosomal membrane and the lumen. Substrate proteins are unfolded before transport into the lysosome lumen, and the transport of substrate proteins requires a molecular chaperone within the lysosomal lumen. The exact roles of this lysosomal chaperone remain to be defined. The mechanisms of chaperone-mediated autophagy are similar to mechanisms of protein import into mitochondria, chloroplasts, and the endoplasmic reticulum. 
 Question: Which is the receptor for substrates of Chaperone Mediated Autophagy?
Output: lamp2a
Context: Chaperone-mediated autophagy is one of several lysosomal pathways of proteolysis. This pathway is activated by physiological stresses such as prolonged starvation. Cytosolic proteins with particular peptide sequence motifs are recognized by a complex of molecular chaperones and delivered to lysosomes. No vesicular traffic is required for this protein degradation pathway, so it differs from microautophagy and macroautophagy. Protein substrates bind to a receptor in the lysosomal membrane, the lysosome-associated membrane protein (lamp) type 2a. Levels of lamp2a in the lysosomal membrane are controlled by alterations in the lamp2a half-life as well as by the dynamic distribution of the protein between the lysosomal membrane and the lumen. Substrate proteins are unfolded before transport into the lysosome lumen, and the transport of substrate proteins requires a molecular chaperone within the lysosomal lumen. The exact roles of this lysosomal chaperone remain to be defined. The mechanisms of chaperone-mediated autophagy are similar to mechanisms of protein import into mitochondria, chloroplasts, and the endoplasmic reticulum. 
 Question: Which is the receptor for substrates of Chaperone Mediated Autophagy?
Output: lysosome-associated membrane protein 2 isoform a
Context: The Todt Organisation (German: Organisation Todt, OT) was a Third Reich civil and military engineering group in Germany named after its founder, Fritz Todt, an engineer and senior Nazi figure. 
 Question: Which industry is Organisation Todt associated with?
Output: military engineering
Context: The story is not linked to the first part of the series. Instead, it focuses on a fictional explanation for the Ryanggang explosion in 2004, in which an unexplained mushroom cloud occurred in North Korea. After reconnaissance satellites detect a large, three-stage Topol intercontinental ballistic missile carrying a nuclear weapon in North Korea, which can strike anywhere in the continental United States, a fictional United States President Adair T. Manning (Peter Coyote) orders a team of U.S. Navy SEALs to destroy the missile and the launch site. The team is led by Lieutenant Robert James (Nicholas Gonzalez). The Pentagon aborts the mission after it receives new information, but by the time the abort order is sent, two SEALs have already parachuted into North Korean territory. James stops the third SEAL from deploying, accidentally knocking the man's helmet against the status indicator mounted near the door. The lieutenant steps onto the makeshift ramp to peer outside, returning to the doorway to inform the rest of men of the abort. The high-speed winds from outside rip the indicator loose and send it flying into the lieutenant's face. Stumbling backwards, James loses his balance and is sucked out of the plane. Callaghan disobeys orders to stand fast, strikes his commanding officer, and follows the first three, taking a radio with him. When North Korean forces led by Commander Hwang (Joseph Steven Yang) find the SEALs, two of the Navy SEALs are killed in a gun battle, and James and Callaghan are captured and tortured by Hwang and his men. After South Korean special forces rescue James and Callaghan, President Manning and the South Korean government send the SEALs and South Korean special forces to destroy the missile site. But after losing radio contact with the SEALs, the President and his top advisers believe that they have been captured again. Under pressure from his military advisor, General Norman Vance (Bruce McGill), the President decides to send B-2 stealth bombers to destroy the site, which would start a full-scale war against North Korea. The SEALs and the South Korean special forces are almost recaptured by Hwang, but he is shot by a defecting officer. James and the South Koreans destroy the missile silo with a bomb before the bombers reach the missile site, which averts the bombing and prevents a full-scale war. A tribunal convicts Callaghan of striking an officer (1 year) and disobeying an officer (10 years). Due to the "black op" nature of the mission, the transcript of the hearing is deemed classified and the charges are expunged from his record, leaving him free to return to his family. Meanwhile, James meets the president in a classified meeting, bringing his mentor Master Chief Scott Boytano (Keith David) as witness to James' receiving of an award. The film closes with Boytano telling James he wasn't red flagged because Boytano had never seen anyone who desired so badly as James did to be a SEAL. During the credits there is a news report on the Ryanggang explosion. 
 Question: Who rescues James and Callaghan?
Output: south korean special forces
Context: Asset Acceptance Capital Corp. is publicly traded (NASDAQ: AACC). 
 Question: Which exchange is Asset Acceptance listed with?
Output: nasdaq
Context: As was discussed in previous concepts, both infectious and noninfectious diseases of the reproductive system can be very serious. But there are ways to keep your reproductive system healthy. What can you do to keep your reproductive system healthy? You can start by making the right choices for overall good health. To be as healthy as you can be, you should: Eat a balanced diet that is high in fiber and low in fat. Drink plenty of water. Get regular exercise. Maintain a healthy weight. Get enough sleep. Avoid using tobacco, alcohol, or other drugs. Manage stress in healthy ways. Keeping your genitals clean is also very important. A daily shower or bath is all that it takes. Females do not need to use special feminine hygiene products. In fact, using them may do more harm than good because they can irritate the vagina or other reproductive structures. You should also avoid other behaviors that can put you at risk. Do not get into contact with another persons blood or other body fluids. For example, never get a tattoo or piercing unless you are sure that the needles have not been used before. This is one of the most important ways to prevent an STI. Of course, the only way to be fully protected against STIs is to refrain from sexual activity. If you are a boy, you should always wear a protective cup when you play contact sports. Contact sports include football, boxing, and hockey. Wearing a cup will help protect the testes from injury. You should also do a monthly self-exam to check for cancer of the testes. If you are a girl and use tampons, be sure to change them every four to six hours. Leaving tampons in for too long can put you at risk of toxic shock syndrome. This is a serious condition. Signs and symptoms of toxic shock syndrome develop suddenly, and the disease can be fatal. The disease involves fever, shock, and problems with the function of several body organs. Girls should also get in the habit of doing a monthly self-exam to check for breast cancer. Although breast cancer is rare in teens, its a good idea to start doing the exam when you are young. It will help you get to know what is normal for you. 
 Question: girls should perform monthly self-exams to check for
Output: breast cancer.
Context: Colonel Muhammadu Abdullahi Wase (died June 1996) was military administrator of Kano State in Nigeria from December 1993 -- 
 Question: Which country is Muhammadu Abdullahi Wase a citizen of?
Output: nigeria
Context: Something that is elastic can return to its original shape after being stretched or compressed. This property is called elasticity. As you stretch or compress an elastic material, it resists the change in shape. It exerts a counter force in the opposite direction. This force is called elastic force. Elastic force causes the material to spring back to its original shape as soon as the stretching or compressing force is released. You can watch a demonstration of elastic force at this URL: (3:57). MEDIA Click image to the left or use the URL below. URL: Elastic force can be very useful. You probably use it yourself every day. A few common uses of elastic force are pictured in Figure 13.25. Did you ever use a resistance band like the one in the figure? When you pull on the band, it stretches but doesnt break. The resistance you feel when you pull on it is elastic force. The resistance of the band to stretching is what gives your muscles a workout. After you stop pulling on the band, it returns to its original shape, ready for the next workout. Springs like the ones in Figure 13.26 also have elastic force when they are stretched or compressed. And like stretchy materials, they return to their original shape when the stretching or compressing force is released. Because of these properties, springs are used in scales to measure weight. They also cushion the ride in a car and provide springy support beneath a mattress. Can you think of other uses of springs? 
 Question: structure that returns to its original shape after being stretched or compressed
Output: spring
Context: Jennifer Hamson (born January 23, 1992) is a professional basketball player who plays for the Los Angeles Sparks in the WNBA. 
 Question: What team does Jennifer Hamson belong to?
Output: los angeles sparks
Context: Traidenis (Polish: Trojden, Belarusian: ) (died 1282) was the Grand Duke of Lithuania from 1270 (or 1269) till 1282. 
 Question: What noble title does Traidenis hold?
Output: grand duke of lithuania
Context: The Department of Transportation Distinguished Service Medal was established by Executive Order 12824 signed by President George H. W. Bush on December 7, 1992. 
 Question: In what year was Transportation Distinguished Service Medal founded?
Output: 1992
Context: In 1959, Michael Courtland (Robertson), a New Orleans real estate developer, has his life shattered when his wife Elizabeth (Bujold) and young daughter Amy are kidnapped. The police recommend that he provide the kidnappers with a briefcase of shredded blank paper instead of the demanded ransom, as the kidnappers will then be more likely to surrender when cornered, rather than attempt to escape with cash in hand. Courtland agrees to this plan. This leads to a bungled car chase in which both kidnappers and victims are killed in a spectacular explosion. Courtland blames himself for the deaths of his wife and daughter. Fifteen years pass. Courtland is morbidly obsessed with his dead wife, and regularly visits a monument he has had built in her memory. The monument is a replica of the church (Basilica di San Miniato al Monte) where he and Elizabeth had met many years before in Florence, Italy. His real estate partner Robert LaSalle (Lithgow) convinces Courtland to tag along on a business trip back to Florence. While there, Courtland revisits the church, and suddenly comes face to face with a young woman named Sandra (Bujold) who looks exactly like his late wife. The already slightly unhinged Courtland begins to court the young woman, and subtly attempts to transform her into a perfect mirror image of his dead wife. Courtland returns to New Orleans with Sandra so they can marry. On their wedding night, Sandra is kidnapped and a ransom note is left behind by her abductors. It is an exact replica of the kidnappers' message from fifteen years before. This time, Courtland decides to deliver the demanded cash. He withdraws massive quantities of money from his accounts and business holdings, financially ruining him and forcing him to sign over his interest in the real estate business to LaSalle. In the process, he discovers that his entire ordeal, including the original kidnapping, had been engineered by LaSalle as a way to gain sole control of Courtland's company share holdings. The now nearly insane Courtland stabs LaSalle to death. Knowing that Sandra must have been a willing accomplice in the plot against him, he goes to the airport to kill the escaping woman. On the plane, Sandra has a flashback to her part in the scheme; she is in fact Courtland's daughter: following the original kidnapping LaSalle concealed her survival and sent her to live in secret with an Italian caretaker. Over the years, LaSalle has told her lies about Courtland, convincing her that her father had not paid the ransom because he didn't love her. Sandra, who has come to love Courtland, attempts suicide on the plane and is taken off the flight in a wheelchair. Courtland sees her and runs toward her, gun drawn. A security guard attempts to stop him but Courtland smashes the briefcase full of money against the guard's head, knocking him unconscious. The briefcase breaks open and all of the money flies out. Sandra, seeing the fluttering bills, stands up and shouts: "Daddy! You brought the money!" Courtland now realizes for the first time who Sandra really is, and father and daughter fall into a deep embrace. 
 Question: What year was Michael's life shattered?
Output: 1959
Context: The National Socialist Motor Corps (German: Nationalsozialistisches Kraftfahrkorps, NSKK) was a paramilitary organization of the Nazi Party (NSDAP) that officially existed from May 1931 to 1945. 
 Question: When was National Socialist Motor Corps abolished?
Output: 1945
Context: When is a person considered an adult? That depends. Most teens become physically mature by the age of 16 or so. But they are not adults in a legal sense until they are older. For example, in the U.S., you must be 18 to vote. Once adulthood begins, it can be divided into three stages: (1) early, (2) middle, and (3) late adulthood. Early adulthood starts at age 18 or 21. It continues until the mid-30s. During early adulthood, people are at their physical peak. They are also usually in good health. The ability to have children is greatest during early adulthood, as well. This is the stage of life when most people complete their education. They are likely to begin a career or take a full-time job. Many people also marry and start a family during early adulthood. Middle adulthood begins in the mid-30s. It continues until the mid-60s. During middle adulthood, people start to show signs of aging. Their hair slowly turns gray. Their skin develops wrinkles. The risk of health problems also increases during middle adulthood. For example, heart disease, cancer, and diabetes become more common during this time. This is the stage of life when people are most likely to achieve career goals. Their children also grow up and may leave home during this stage. Late adulthood begins in the mid-60s. It continues until death. This is the stage of life when most people retire from work. They are also likely to reflect on their life. They may focus on their grandchildren. During late adulthood, people are not as physically able. For example, they usually have less muscle and slower reflexes. Their immune system also doesnt work as well as it used to. As a result, they have a harder time fighting diseases like the flu. The risk of developing diseases such as heart disease and cancer continues to rise. Arthritis is also common. In arthritis, joints wear out and become stiff and painful. As many as one in four late adults may develop Alzheimers disease. In this disease, brain changes cause mental abilities to decrease. This family picture shows females in each of the three stages of life. Which stage does each represent? Despite problems such as these, many people remain healthy and active into their 80s or even 90s. Do you want to be one of them? Then adopt a healthy lifestyle now and follow it for life. Doing so will increase your chances of staying healthy and active to an old age. Exercising the body and brain help prevent the physical and mental effects of aging. 
 Question: heart disease, cancer, and diabetes become more common during this time.
Output: middle adulthood
Context: As of the census of 2000, there were 218,590 people, 79,667 households, and 60,387 families residing in the county. The population density was 496 people per square mile (192/km). There were 83,146 housing units at an average density of 189 per square mile (73/km). The racial makeup of the county was 86.77% Race (United States Census), 9.27% Race (United States Census), 0.23% Race (United States Census), 1.52% Race (United States Census), 0.06% Race (United States Census), 0.69% from Race (United States Census), and 1.47% from two or more races. 1.91% of the population were Race (United States Census) or Race (United States Census) of any race. 22.5% were of German people, 13.1% Irish people, 9.8% Italian people, 9.2% English, 8.1% "American" and 6.0% Polish ancestry. 
 Question: Which ancestral group is smaller: English or Italian?
Output: english
Context: Sigma Editions is an independent record label founded in 1998 by Rosy Parlane and Dion Workman (both ex-members of Thela). 
 Question: What year was Sigma Editions created in?
Output: 1998
Context: After the 2004 Asian tsunami disaster, four independent volunteers, with little money and no experience, race off to volunteer in tsunami ravaged Sri Lanka. They meet up by fate at the Colombo airport and form a volunteer team. They rent a van, fill it with supplies and start driving down the coast to see where they can help. They stumble into a tribal village called Peraliya, which has been destroyed by a forty foot wave. During the time the wave hit Peraliya, a train called "The Queen of the Sea" was passing by and was washed away killing over 2500 passengers and villagers. The Four volunteers set up a first aid station and found themselves in charge of running a refugee camp with over 3000 people. Their initial two week journey turns into a year long odyssey of heartbreak and hope as the villagers turn against them when donated tsunami relief money does not materialize. The volunteers concentrate on the bigger picture and break every rule in the 'Disaster Aid Books'. 
 Question: What kind of natural disater was ravaging Sri Lanka?
Output: tsunami
Context: Hoping to rebound from their road loss to the Patriots, the Rams went home for a Week 9 NFC West duel with the Arizona Cardinals. In the first quarter, St. Louis struck first as QB Marc Bulger completed an 80-yard TD pass to WR Derek Stanley. In the second quarter, the Cardinals responded with a vengeance as safety Antrel Rolle returned an interception 40 yards for a touchdown, kicker Neil Rackers got a 36-yard field goal, RB Tim Hightower got a 30-yard TD run, and former Rams QB Kurt Warner completed a 56-yard TD pass to WR Jerheme Urban. In the third quarter, Arizona increased its lead as Warner completed a 7-yard TD pass to WR Anquan Boldin. In the fourth quarter, the Rams tried to come back as Bulger completed a 3-yard TD pass to WR Torry Holt (with a failed 2-point conversion). However, the Cardinals flew away as Rackers nailed a 30-yard field goal. During the game, the Rams inducted former Head Coach Dick Vermeil (who helped the franchise win Super Bowl XXXIV) onto the Rams Ring of Honor. 
 Question: Who caught the first touchdown of the game?
Output: derek stanley
Context: Hoping to rebound from their road loss to the Patriots, the Rams went home for a Week 9 NFC West duel with the Arizona Cardinals. In the first quarter, St. Louis struck first as QB Marc Bulger completed an 80-yard TD pass to WR Derek Stanley. In the second quarter, the Cardinals responded with a vengeance as safety Antrel Rolle returned an interception 40 yards for a touchdown, kicker Neil Rackers got a 36-yard field goal, RB Tim Hightower got a 30-yard TD run, and former Rams QB Kurt Warner completed a 56-yard TD pass to WR Jerheme Urban. In the third quarter, Arizona increased its lead as Warner completed a 7-yard TD pass to WR Anquan Boldin. In the fourth quarter, the Rams tried to come back as Bulger completed a 3-yard TD pass to WR Torry Holt (with a failed 2-point conversion). However, the Cardinals flew away as Rackers nailed a 30-yard field goal. During the game, the Rams inducted former Head Coach Dick Vermeil (who helped the franchise win Super Bowl XXXIV) onto the Rams Ring of Honor. 
 Question: Who caught the first touchdown of the game?
Output: wr derek stanley
Context: Sofia Maria Ekwall, (1826--1897), was a Swedish woman judged for two murders and for the murder of her father. 
 Question: For what crime was Sofia Maria Ekwall prosecuted?
Output: murder
Context: Chediak-Higashi syndrome (CHS) is a rare autosomal recessive disorder in which an immune deficiency occurs in association with pigmentation abnormalities. Most patients who do not undergo bone marrow transplantation die of a lymphoproliferative syndrome, though some patients with CHS have a relatively milder clinical course of the disease. The large size of the LYST gene, defective in CHS, has made it difficult to screen for mutations in a large number of patients. Only 8 mutations have been identified so far, and all lead to a truncated LYST protein. We conducted protein truncation tests on this gene in 8 patients with CHS. Different LYST mutations were identified in all subjects through this approach, strengthening the observation of a high frequency of truncated LYST proteins as the genetic cause of CHS. 
 Question: Which syndrome is associated with mutations in the LYST gene?
Output: chediak-higashi syndrome
Context: The Giants failed to capitalize on their win from the week before and once again were defeated by the Redskins for the season sweep. Washington never trailed in this game and forced Eli Manning into three interceptions. Although the Giants recorded two off of Rex Grossman, they never were able to get into any sort of offensive groove and lost 23-10. Washington led 17-3 at halftime and never looked back. Grossman threw for 185 yards and a touchdown to Santana Moss. Jabar Gaffney led the Redskins with 85 yards receiving while Hakeem Nicks recorded 73 for the Giants. Manning finished with 257 yards. 
 Question: Who had the most receiving yards for Washington?
Output: jabar gaffney
Context: Ceraunius Tholus is a volcano on Mars located in the Tharsis quadrangle at 24.25 north latitude and 262.75 east longitude, part of the Uranius group of volcanoes. 
 Question: On what moon or planet can Ceraunius Tholus be found?
Output: mars
Context: Transcription-coupled repair (TCR) is a subpathway of nucleotide excision repair (NER) that acts specifically on lesions in the transcribed strand of expressed genes. First reported in mammalian cells, TCR was then documented in Escherichia coli. In this organism, an RNA polymerase arrested at a lesion is displaced by the transcription repair coupling factor, Mfd. This protein recruits the NER lesion-recognition factor UvrA, and then dissociates from the DNA. UvrA binds UvrB, and the assembled UvrAB* complex initiates repair. In mutants lacking active Mfd, TCR is absent. A gene transcribed by the bacteriophage T7 RNA polymerase in E. coli also requires Mfd for TCR. The CSB protein (missing or defective in cells of patients with Cockayne syndrome, complementation group B) is essential for TCR in humans. CSB and its homologs in higher eukaryotes are likely functional equivalents of Mfd. 
 Question: Which gene strand is targeted by transcription-coupled repair (TCR)?
Output: the transcribed strand
Context: Although alpha-synuclein (alpha-syn) has been implicated as a major component of the abnormal filaments that form glial cytoplasmic inclusions (GCIs) in multiple system atrophy (MSA), it is uncertain if GCIs are homogenous and contain full-length alpha-syn. Since this has implications for hypotheses about the pathogenesis of GCIs, we used a novel panel of antibodies to defined regions throughout alpha-syn in immunohistochemical epitope mapping studies of GCIs in MSA brains. Although the immunostaining profile of GCIs with these antibodies was similar for all MSA brains, there were significant differences in the immunoreactivity of the alpha-syn epitopes detected in GCIs. Notably, carboxy-terminal alpha-syn epitopes were immunodominant in GCIs, but the entire panel of antibodies immunostained cortical Lewy bodies (LBs) in dementia with LBs brain with similar intensity. While the distribution of alpha-syn labeled GCIs paralleled that previously reported using silver stains, antibodies to carboxy-terminal alpha-syn epitopes revealed a previously undescribed burden of GCIs in the MSA hippocampal formation. Finally, Western blots demonstrated detergent insoluble monomeric and high-molecular weight alpha-syn species in GCI rich MSA cerebellar white matter. Collectively, these data indicate that alpha-syn is a prominent component of GCIs in MSA, and that GCIs and LBs may result from cell type specific conformational or post-translational permutations in alpha-syn. 
 Question: Against which protein is the antibody used for immonostaining of Lewy bodies raised?
Output: alpha-synuclein
Context: Anderson-Fabry disease (referred to as Fabry disease) is an X-linked disorder characterized by a deficiency of the lysosomal enzyme alpha-galactosidase A and the subsequent accumulation in various tissues of globotriaosylceramide (Gb(3)), the main substrate of the defective enzyme. Enzyme replacement therapy (ERT) offers a specific treatment for patients with Fabry disease, though monitoring of treatment is hampered by a lack of surrogate markers of response. In this study, the efficacy of long-term ERT in six Fabry hemizygotes and two symptomatic heterozygotes has been evaluated. Patients were administered recombinant alpha-galactosidase A every 2 weeks for up to a year. The efficacy of ERT was assessed by monitoring symptomatology and renal function. Urinary glycolipid concentration was estimated by a novel tandem mass spectrometric method. Urine glycolipid (Gb(3)) was elevated at baseline and fell impressively on ERT where patients were hemizygotes and in the absence of renal transplantation. In heterozygotes and in a recipient of a renal allograft, elevations and changes in urine glycolipids were less pronounced. In one patient, after several months of ERT, there was a transient increase in Gb(3) concentrations to baseline (pre-ERT) levels, associated with the presence of antibodies to the recombinant alpha-galactosidase A. The marked decline in urine Gb(3) on ERT, and its subsequent increase in association with an inhibitory antibody response, suggest that this analyte deserves further investigation as a potential marker of disease severity and response to treatment. 
 Question: Which is the defective protein causing the lysosomal storage disease Fabry?
Output: alpha-galactosidase a
Context: Coming off their last-second victory over the Bengals, the Broncos would play their Week 2 home opener against the Cleveland Browns. In the first quarter, Denver would trail early as Browns kicker Phil Dawson got a 22-yard field goal. Afterwards, the Broncos took the lead as quarterback Kyle Orton completed a 2-yard touchdown pass to tight end Tony Scheffler. Cleveland would creep close as Dawson made a 47-yard field goal, but Denver would answer as kicker Matt Prater got a 23-yard field goal in the second quarter and a 38-yard field goal in the third quarter. In the fourth, the Broncos pulled away as fullback Peyton Hillis got a 2-yard touchdown run and running back Correll Buckhalter got a 45-yard touchdown run. 
 Question: Which player kicked the second longest field goal?
Output: matt prater
Context: Community-associated methicillin resistant Staphylococcus aureus (CA-MRSA) has become a severe health concern because of its treatment difficulties. Herein, we report the synthesis and biological evaluation of two phenazine natural products and a series of phenazines that show promising activities against MRSA with MIC values in the low micromolar range. Basic studies revealed that these compounds are bacteriostatic agents. The most active compound also displayed promising IC50 values against HaCat cells. Finally, a QSAR model was developed to understand the key structural features of the molecules. 
 Question: What is MRSA?
Output: mrsa
Context: Community-associated methicillin resistant Staphylococcus aureus (CA-MRSA) has become a severe health concern because of its treatment difficulties. Herein, we report the synthesis and biological evaluation of two phenazine natural products and a series of phenazines that show promising activities against MRSA with MIC values in the low micromolar range. Basic studies revealed that these compounds are bacteriostatic agents. The most active compound also displayed promising IC50 values against HaCat cells. Finally, a QSAR model was developed to understand the key structural features of the molecules. 
 Question: What is MRSA?
Output: methicillin-resistant s. aureus
Context: Coming off their bye week, the Buccaneers were still looking for their first win of the season. The Bucs traveled to the Louisiana Superdome for their third divisional match-up in a rowthis time, against the New Orleans Saints. The Bucs scored first as rookie QB Bruce Gradkowski threw an 18-yard TD pass to WR Joey Galloway in the first quarter; the Saints responded with a 21-yard field goal from kicker John Carney. The Saints continued scoring, with a 24-yard TD run from RB Deuce McAllister in the second quarter, and a 9-yard TD pass to TE Ernie Conwell in the third quarter. The Bucs finally responded with a 1-yard TD run from FB Mike Alstott, and took the lead in the fourth quarter with Gradkowski's 3-yard TD pass to TE Alex Smith. Unfortunately for the Bucs, a special teams breakdown led to Saints RB Reggie Bush getting his inaugural NFL touchdown on a 65-yard punt return, which sealed the win for the Saints. 
 Question: Which team scored the most points in the third quarter?
Output: the saints
Context: Days of Future Passed is the second album and first concept album by English rock band The Moody Blues, released in November 1967 by Deram Records. 
 Question: What was the record label of Days of Future Passed?
Output: deram records
Context: The Brokenwood Mysteries is a New Zealand detective drama television series that premiered on Prime in 2014. 
 Question: What country did The Brokenwood Mysteries originate?
Output: new zealand
Context: Dorsa Ewing is a wrinkle ridge at 10.2S 39.4W in Oceanus Procellarum on the Moon. 
 Question: What celestial body can Dorsa Ewing be found on?
Output: moon
Context: Hans Ernst von Kottwitz (1 September 1757 -- 13 May 1843) was a German Pietist and philanthropist. 
 Question: What was Hans Ernst von Kottwitz's nationality?
Output: german
Context: Nevertheless, the Marder II (and similar Marder III) provided a great increase in firepower over contemporary German tanks during 1942 and into 1943. 
 Question: Which was the official year for the approval of Marder II?
Output: 1942
Context: Over the next year, however, the Polish forces were subject to attrition, as the Sejm again refused to raise taxes and pay the army, resulting in mass desertions of unpaid soldiery. The Polish problems were further aggravated by the incompetent leadership of hetman Micha Kazimierz Pac, who obstructed Sobieski's leadership, while the Ottomans continued to receive reinforcements. Nonetheless in 1674 the Commonwealth resumed the offensive, taking advantage of a new Muscovy-Ottoman conflict that year, and the Polish-Ottoman war remained undecided.:275 Sobieski's force of 6,000 defeated 20,000 Turks and Tatars under Ibrahim Shyshman in the battle of Lwow in August 1675.:653 Even after the Battle of Trembowla, the Sejm still refused his pleas for more funds and a larger army.:653 In 1676, after Sobieski's 16,000 withstood the two-week siege of Zurawno, by 100,000 men under Ibrahim Pasha, a new peace treaty was signed, the Treaty of Zurawno.:655 The peace treaty partially reversing those from Buczacz: the Ottomans kept approximately two thirds of the territories they gained in 1672, and the Commonwealth no longer was obliged to pay any kind of tribute to the Empire; a large number of Polish prisoners were released by the Ottomans. 
 Question: Why were soldiers deserting the Sejm?
Output: unpaid soldiery
Context: Over the next year, however, the Polish forces were subject to attrition, as the Sejm again refused to raise taxes and pay the army, resulting in mass desertions of unpaid soldiery. The Polish problems were further aggravated by the incompetent leadership of hetman Micha Kazimierz Pac, who obstructed Sobieski's leadership, while the Ottomans continued to receive reinforcements. Nonetheless in 1674 the Commonwealth resumed the offensive, taking advantage of a new Muscovy-Ottoman conflict that year, and the Polish-Ottoman war remained undecided.:275 Sobieski's force of 6,000 defeated 20,000 Turks and Tatars under Ibrahim Shyshman in the battle of Lwow in August 1675.:653 Even after the Battle of Trembowla, the Sejm still refused his pleas for more funds and a larger army.:653 In 1676, after Sobieski's 16,000 withstood the two-week siege of Zurawno, by 100,000 men under Ibrahim Pasha, a new peace treaty was signed, the Treaty of Zurawno.:655 The peace treaty partially reversing those from Buczacz: the Ottomans kept approximately two thirds of the territories they gained in 1672, and the Commonwealth no longer was obliged to pay any kind of tribute to the Empire; a large number of Polish prisoners were released by the Ottomans. 
 Question: Why were soldiers deserting the Sejm?
Output: refused to raise taxes
Context: Over the next year, however, the Polish forces were subject to attrition, as the Sejm again refused to raise taxes and pay the army, resulting in mass desertions of unpaid soldiery. The Polish problems were further aggravated by the incompetent leadership of hetman Micha Kazimierz Pac, who obstructed Sobieski's leadership, while the Ottomans continued to receive reinforcements. Nonetheless in 1674 the Commonwealth resumed the offensive, taking advantage of a new Muscovy-Ottoman conflict that year, and the Polish-Ottoman war remained undecided.:275 Sobieski's force of 6,000 defeated 20,000 Turks and Tatars under Ibrahim Shyshman in the battle of Lwow in August 1675.:653 Even after the Battle of Trembowla, the Sejm still refused his pleas for more funds and a larger army.:653 In 1676, after Sobieski's 16,000 withstood the two-week siege of Zurawno, by 100,000 men under Ibrahim Pasha, a new peace treaty was signed, the Treaty of Zurawno.:655 The peace treaty partially reversing those from Buczacz: the Ottomans kept approximately two thirds of the territories they gained in 1672, and the Commonwealth no longer was obliged to pay any kind of tribute to the Empire; a large number of Polish prisoners were released by the Ottomans. 
 Question: Why were soldiers deserting the Sejm?
Output: the sejm again refused to raise taxes and pay the army
Context: Marjanovic took over Ciguli Miguli only after his proposal for Nikola Tesla, a biography of the famous engineer and inventor, had been rejected by Jadran Film. 
 Question: What production company was involved in Ciguli Miguli?
Output: jadran film
Context: The National Museum of Aleppo (Arabic: ) is the largest museum in the city of Aleppo, Syria, and was founded in 1931. 
 Question: What was the date of the opening of National Museum of Aleppo?
Output: 1931
Context: Alpha-synuclein accumulates in the brains of sporadic Parkinson's disease patients as a major component of Lewy bodies, and mutations in alpha-synuclein are associated with familial forms of Parkinson's disease. The pathogenic mechanisms that precede and promote the aggregation of alpha-synuclein into Lewy bodies in neurons remain to be determined. Here, we constructed a series of alpha-synuclein-enhanced green fluorescent protein (alpha-synucleinEGFP, SynEGFP) fusion proteins to address whether the Parkinson's disease-associated mutations alter the subcellular distribution of alpha-synuclein, and to use as a tool for experimental manipulations to induce aggregate formation. When transfected into mouse cultured primary neurons, the 49-kDa alpha-synucleinEGFP fusion proteins are partially truncated to a approximately 27-kDa form. This non-fluorescent carboxy-terminally modified fusion protein spontaneously forms inclusions in the neuronal cytoplasm. A marked increase in the accumulation of inclusions is detected following treatment with each of three proteasome inhibitors, n-acetyl-leu-leu-norleucinal, lactacystin and MG132. Interestingly, Ala30Pro alpha-synucleinEGFP does not form the cytoplasmic inclusions that are characteristic of wild-type and Ala53Thr alpha-synucleinEGFP, supporting the idea that the Ala30Pro alpha-synuclein protein conformation differs from wild-type alpha-synuclein. Similar inclusions are formed if alpha-synuclein carboxy-terminus is modified by the addition of a V5/6xHistidine epitope tag. By contrast, overexpression of unmodified alpha-synuclein does not lead to aggregate formation. Furthermore, synphilin-1, an alpha-synuclein interacting protein also found in Lewy bodies, colocalizes with the carboxy-terminally truncated alpha-synuclein fusion protein in discrete cytoplasmic inclusions.Our finding that manipulations of the carboxy-terminus of alpha-synuclein lead to inclusion formation may provide a model for studies of the pathogenic mechanisms of alpha-synuclein aggregation in Lewy bodies. 
 Question: Which is the primary protein component of Lewy bodies?
Output: αsyn
Context: Alpha-synuclein accumulates in the brains of sporadic Parkinson's disease patients as a major component of Lewy bodies, and mutations in alpha-synuclein are associated with familial forms of Parkinson's disease. The pathogenic mechanisms that precede and promote the aggregation of alpha-synuclein into Lewy bodies in neurons remain to be determined. Here, we constructed a series of alpha-synuclein-enhanced green fluorescent protein (alpha-synucleinEGFP, SynEGFP) fusion proteins to address whether the Parkinson's disease-associated mutations alter the subcellular distribution of alpha-synuclein, and to use as a tool for experimental manipulations to induce aggregate formation. When transfected into mouse cultured primary neurons, the 49-kDa alpha-synucleinEGFP fusion proteins are partially truncated to a approximately 27-kDa form. This non-fluorescent carboxy-terminally modified fusion protein spontaneously forms inclusions in the neuronal cytoplasm. A marked increase in the accumulation of inclusions is detected following treatment with each of three proteasome inhibitors, n-acetyl-leu-leu-norleucinal, lactacystin and MG132. Interestingly, Ala30Pro alpha-synucleinEGFP does not form the cytoplasmic inclusions that are characteristic of wild-type and Ala53Thr alpha-synucleinEGFP, supporting the idea that the Ala30Pro alpha-synuclein protein conformation differs from wild-type alpha-synuclein. Similar inclusions are formed if alpha-synuclein carboxy-terminus is modified by the addition of a V5/6xHistidine epitope tag. By contrast, overexpression of unmodified alpha-synuclein does not lead to aggregate formation. Furthermore, synphilin-1, an alpha-synuclein interacting protein also found in Lewy bodies, colocalizes with the carboxy-terminally truncated alpha-synuclein fusion protein in discrete cytoplasmic inclusions.Our finding that manipulations of the carboxy-terminus of alpha-synuclein lead to inclusion formation may provide a model for studies of the pathogenic mechanisms of alpha-synuclein aggregation in Lewy bodies. 
 Question: Which is the primary protein component of Lewy bodies?
Output: α-synuclein