niryuu/sni-each-converted huggingface dataset:
Context: At the start of World War II, the 24th Infantry was stationed at Fort Benning as school troops for the Infantry School. They participated in the Carolina Maneuvers of October - December 1941. During World War II, the 24th Infantry fought in the South Pacific Theatre as a separate regiment. Deploying on 4 April 1942 from the San Francisco Port of Embarkation, the regiment arrived in the New Hebrides Islands on 4 May 1942. The 24th moved to Guadalcanal on 28 August 1943, and was assigned to the XIV Corps. 1st Battalion deployed to Bougainville, attached to the 37th Infantry Division, from March to May 1944 for perimeter defense duty. The regiment departed Guadalcanal on 8 December 1944, and landed on Saipan and Tinian on 19 December 1944 for Garrison Duty that included mopping up the remaining Japanese forces that had yet to surrender. The regiment was assigned to the Pacific Ocean Area Command on 15 March 1945, and then to the Central Pacific Base Command on 15 May 1945, and to the Western pacific Base Command on 22 June 1945. The regiment departed Saipan and Tinian on 9 July 1945, and arrived on the Kerama Islands off Okinawa on 29 July 1945. At the end of the war, the 24th took the surrender of forces on the island of Aka-shima, the first formal surrender of a Japanese Imperial Army garrison. The regiment remained on Okinawa through 1946. 
 Question: What happened second: moved to Guadalcanal or arrived on the Kerama Islands?
Output: arrived on the kerama islands
Context: Souvenirs de Munich is a quadrille on themes from Wagner's Tristan and Isolde, for piano, four hands by Emmanuel Chabrier. 
 Question: What instrument is Souvenirs de Munich for?
Output: piano, four hands
Context: Mowat-Wilson syndrome (MWS) is a rare genetic condition where variable and multiple congenital anomalies including Hirschsprung's disease, intellectual disability, and prominent facial features are present. At molecular level, MWS is characterized by many different described mutations in the zinc finger E-box protein 2 (ZEB2) gene, ultimately leading to loss of gene function. This report is the first to describe the association of MWS with two different asynchronous malignant brain tumors (medulloblastoma and glioblastoma) occurring in a child. 
 Question: Which gene is responsible for the development of the Mowat-Wilson syndrome?
Output: zeb2
Context: Mowat-Wilson syndrome (MWS) is a rare genetic condition where variable and multiple congenital anomalies including Hirschsprung's disease, intellectual disability, and prominent facial features are present. At molecular level, MWS is characterized by many different described mutations in the zinc finger E-box protein 2 (ZEB2) gene, ultimately leading to loss of gene function. This report is the first to describe the association of MWS with two different asynchronous malignant brain tumors (medulloblastoma and glioblastoma) occurring in a child. 
 Question: Which gene is responsible for the development of the Mowat-Wilson syndrome?
Output: zfhx1b
Context: Mowat-Wilson syndrome (MWS) is a rare genetic condition where variable and multiple congenital anomalies including Hirschsprung's disease, intellectual disability, and prominent facial features are present. At molecular level, MWS is characterized by many different described mutations in the zinc finger E-box protein 2 (ZEB2) gene, ultimately leading to loss of gene function. This report is the first to describe the association of MWS with two different asynchronous malignant brain tumors (medulloblastoma and glioblastoma) occurring in a child. 
 Question: Which gene is responsible for the development of the Mowat-Wilson syndrome?
Output: sip-1
Context: Hill+Knowlton Strategies is a global public relations company, headquartered in New York City, United States, with 90 offices in 52 countries. 
 Question: Which industry is Hill+Knowlton Strategies associated with?
Output: public relations
Context: With the recent introduction of inhibitors of mammalian target of rapamycin (mTOR) in oncology, distinct cutaneous and oral adverse events have been identified. In fact, stomatitis and rash are documented as the most frequent and potentially dose-limiting side effects. Clinically, mTOR inhibitor-associated stomatitis (mIAS) more closely resembles aphthous stomatitis than oral mucositis due to conventional anticancer therapies. While most cases of mIAS are mild to moderate and self-limiting, more severe and persistent mIAS can become a dose-limiting toxicity. Small ulcerations may cause significant pain and mucosal sensitivity may occur in the absence of clinical changes. Use of clinical assessment tools that are primarily driven by ulceration size may underestimate mIAS, and assessment should include patient-reported outcomes. This article provides an up-to-date review of the clinical presentation, terminology, pathogenesis, assessment and management of mIAS and other mTOR inhibitor-associated oral adverse events. In addition, areas of future research are considered. 
 Question: What does mTOR stands for?
Output: mammalian target of rapamycin
Context: Vera Drake is a 2004 British drama film written and directed by Mike Leigh, telling the story of a working-class woman in London in 1950 who performs illegal abortions. 
 Question: Which person directed Vera Drake?
Output: mike leigh
Context: Oxidative stress activates the c-Jun N-terminal kinase (JNK) pathway. However, the exact mechanisms by which reactive oxygen species (ROS) activate JNK are unclear. We found that the ability of hydrogen peroxide (H(2)O(2)) to induce JNK activation varied in different cell types. Pyrrolidine dithiocarbamate (PDTC), a presumed antioxidant, induced JNK activation on its own and enhanced JNK activation by H(2)O(2) in many cell types, including Jurkat, HEK293, and LNCaP and Tsu-Pr1 prostate cancer cells. The activation of JNK by PDTC, in the presence or absence of exogenous H(2)O(2), was dependent on its chelating ability to metal ions, most likely copper ions. Despite the strong JNK-activating ability, H(2)O(2) plus PDTC did not induce significant activation of the upstream kinases, SEK1/MKK4 and MKK7. However, the JNK inactivation rate was slower in cells treated with H(2)O(2) plus PDTC compared with the rate in cells treated with ultraviolet C (UV-C). Treatment of H(2)O(2) plus PDTC significantly decreased the expression levels of a JNK phosphatase, M3/6 (also named hVH-5), but not the levels of other phosphatases (PP2A and PP4). In contrast, UV-C irradiation did not cause the down-regulation of M3/6. These results suggest that JNK activation by H(2)O(2) plus PDTC resulted from the down-regulation of JNK phosphatases. Our data also reveal a necessity to carefully evaluate the pharmacological and biochemical properties of PDTC. 
 Question: Which protein is affected by dusp8 activation?
Output: jnk
Context: Proadrenomedullin (ProADM) confers additional prognostic information to established clinical risk scores in lower respiratory tract infections (LRTI). We aimed to derive a practical algorithm combining the CURB65 score with ProADM-levels in patients with community-acquired pneumonia (CAP) and non-CAP-LRTI. We used data of 1359 patients with LRTI enrolled in a multicenter study. We chose two ProADM cut-off values by assessing the association between ProADM levels and the risk of adverse events and mortality. A composite score (CURB65-A) was created combining CURB65 classes with ProADM cut-offs to further risk-stratify patients. CURB65 and ProADM predicted both adverse events and mortality similarly well in CAP and non-CAP-LRTI. The combined CURB65-A risk score provided better prediction of death and adverse events than the CURB65 score in the entire cohort and in CAP and non-CAP-LRTI patients. Within each CURB65 class, higher ProADM-levels were associated with an increased risk of adverse events and mortality. Overall, risk of adverse events (3.9%) and mortality (0.65%) was low for patients with CURB65 score 0-1 and ProADM 0.75 nmol/l (CURB65-A risk class I); intermediate (8.6% and 2.6%, respectively) for patients with CURB65 score of 2 and ProADM 1.5 nmol/l or CURB classes 0-1 and ProADM levels between 0.75-1.5 nmol/L (CURB65-A risk class II), and high (21.6% and 9.8%, respectively) for all other patients (CURB65-A risk class III). If outpatient treatment was recommended for CURB65-A risk class I and short hospitalization for CURB65-A risk class II, 17.9% and 40.8% of 1217 hospitalized patients could have received ambulatory treatment or a short hospitalization, respectively. The new CURB65-A risk score combining CURB65 risk classes with ProADM cut-off values accurately predicts adverse events and mortality in patients with CAP and non-CAP-LRTI. Additional prospective cohort or intervention studies need to validate this score and demonstrate its safety and efficacy for the management of patients with LRTI. Procalcitonin-guided antibiotic therapy and hospitalisation in patients with lower respiratory tract infections: the prohosp study; isrctn.org Identifier: ISRCTN: ISRCTN95122877. 
 Question: CURB65 score is used for stratification of which disease?
Output: pneumonia
Context: On November 13, 1982, 15-year-old Scott Safran of Cherry Hill, New Jersey, set a world record of 41,336,440 points on the arcade game Asteroids, beating the 40,101,910 point score set by Leo Daniels of Carolina Beach on February 6, 1982. In 1998, to congratulate Safran on his accomplishment, the Twin Galaxies Intergalactic Scoreboard searched for him for four years until 2002, when it was discovered that he had died in an accident in 1989. In a ceremony in Philadelphia on April 27, 2002, Walter Day of Twin Galaxies presented an award to the surviving members of Safrans family, commemorating the Asteroid Champions achievement. On April 5, 2010, John McAllister broke Safrans record with a high score of 41,838,740 in a 58-hour Internet livestream. 
 Question: Who is the most recent holder of the Asteroid award?
Output: john mcallister
Context: Sitakunda massacre (Bengali: ) refers to the massacre of Hindu pilgrims on 15 February 1950. 
 Question: The date of Sitakunda massacre was what?
Output: 15 february 1950
Context: Random Hearts is a 1999 American romantic drama film directed by Sydney Pollack and starring Harrison Ford and Kristin Scott Thomas. 
 Question: The director of Random Hearts is who?
Output: sydney pollack
Context: Tuberculosis (Tb) continues to be a dreadful infection worldwide with nearly 1.5 million deaths in 2013. Furthermore multi/extensively drug-resistant Tb (MDR/XDR-Tb) worsens the condition. Recently approved anti-Tb drugs (bedaquiline and delamanid) have the potential to induce arrhythmia and are recommended in patients with MDR-Tb when other alternatives fail. The goal of elimination of Tb by 2050 will not be achieved without an effective new vaccine. The recent advancement in the development of Tb vaccines is the keen focus of this review. To date, Bacille Calmette Guerin (BCG) is the only licensed Tb vaccine in use, however its efficacy in pulmonary Tb is variable in adolescents and adults. There are nearly 15 vaccine candidates in various phases of clinical trials, includes five protein or adjuvant vaccines, four viral-vectored vaccines, three mycobacterial whole cell or extract vaccines, and one each of the recombinant live and the attenuated Mycobacterium tuberculosis (Mtb) vaccine. 
 Question: Which disease can be treated with Delamanid?
Output: tuberculosis
Context: Kahekordne mang (English: Double Play) is a novel by Estonian author Karl Ristikivi. 
 Question: The writer of Kahekordne mang is who?
Output: karl ristikivi
Context: However, the Seven Years' War ended on February 10, 1763 with the signing of the Treaty of Paris in Paris, France. Also, Silang was assassinated on May 28, 1763 by an Indio under the employ of the friars. The Spanish were then able to focus on the uprising and mustered forces to surround Palaris. The Spanish friars, who were allowed to stay in the province, also started a campaign to persuade Pangasinan residents of the futility of the Palaris Revolt. By September 1763, news of the peace treaty reached Pangasinan and army of Palaris' men surrendered and returned to normal life amid the Spanish offensive. Palaris tried to fend off the offensive at the village of Mabalitec near the Agno River between Binalatongan and Bayambang in December 1763. To prevent the Spanish from seeking lodging in his hometown, he ordered his men to raze Binalatongan. But the Spanish won the Battle of Mabalitec, demoralizing Palaris' forces. The town of Binalatongan was rebuilt in another site between December 1763 to June 1764 and renamed San Carlos , in honor of the reigning King Carlos III of Spain. Palaris' forces made a last stand at the town of San Jacinto, Pangasinan, but they were defeated. Palaris' advisers, Andres Lopez and Juan de Vera Oncantin, were captured. They would later be hanged. 
 Question: Which happened later, the the assassination of Silang or the Battle of Mabalitec?
Output: battle of mabalitec
Context: Oil is a liquid fossil fuel that is extremely useful because it can be transported easily and can be used in cars and other vehicles. Oil is currently the single largest source of energy in the world. Oil from the ground is called crude oil, which is a mixture of many different hydrocarbons. Crude oil is a thick dark brown or black liquid hydrocarbon. Oil also forms from buried dead organisms, but these are tiny organisms that live on the sea surface and then sink to the seafloor when they die. The dead organisms are kept away from oxygen by layers of other dead creatures and sediments. As the layers pile up, heat and pressure increase. Over millions of years, the dead organisms turn into liquid oil. In order to be collected, the oil must be located between a porous rock layer and an impermeable layer (Figure 1.1). Trapped above the porous rock layer and beneath the impermeable layer, the oil will remain between these layers until it is extracted from the rock. Oil (red) is found in the porous rock layer (yellow) and trapped by the impermeable layer (brown). The folded structure has allowed the oil to pool so a well can be drilled into the reservoir. To separate the different types of hydrocarbons in crude oil for different uses, the crude oil must be refined in refineries like the one shown in Figure 1.2. Refining is possible because each hydrocarbon in crude oil boils at a different temperature. When the oil is boiled in the refinery, separate equipment collects the different compounds. Most of the compounds that come out of the refining process are fuels, such as gasoline, diesel, and heating oil. Because these fuels are rich sources of energy and can be easily transported, oil provides about 90% of the energy used for transportation around the world. The rest of the compounds from crude oil are used for waxes, plastics, fertilizers, and other products. Gasoline is in a convenient form for use in cars and other transportation vehicles. In a car engine, the burned gasoline mostly turns into carbon dioxide and water vapor. The fuel releases most of its energy as heat, which causes the gases to expand. This creates enough force to move the pistons inside the engine and to power the car. Refineries like this one separate crude oil into many useful fuels and other chemi- cals. Click image to the left or use the URL below. URL: The United States does produce oil, but the amount produced is only about one-quarter as much as the nation uses. The United States has only about 1.5% of the worlds proven oil reserves, so most of the oil used by Americans must be imported from other nations. The main oil-producing regions in the United States are the Gulf of Mexico, Texas, Alaska, and California (Figure As in every type of mining, mining for oil has environmental consequences. Oil rigs are unsightly (Figure 1.4), and spills are too common (Figure 1.5). Click image to the left or use the URL below. URL: Offshore well locations in the Gulf of Mex- ico. Note that some wells are located in very deep water. Drill rigs at the San Ardo Oil Field in Monterey, California. 
 Question: crude oil is a mixture of many different
Output: hydrocarbons
Context: The Flute sonata in E minor (HWV 379) was composed (circa 1727-28) by George Frideric Handel for flute and keyboard (harpsichord). 
 Question: What is the musical instrument Flute sonata in E minor (HWV 379) was intended for?
Output: flute
Context: The 1688 Glorious Revolution replaced James II and VII with his Protestant daughter Mary II and her husband William III and II. Since neither Mary or her sister Anne had surviving children, the 1701 Act of Settlement ensured a Protestant successor by excluding Catholics from the English and Irish thrones, and that of Great Britain after the 1707 Act of Union. When Anne became the last Stuart monarch in 1702, her heir was the distantly related but Protestant Sophia of Hanover, not her Catholic half-brother James Francis Edward. Sophia died two months before Anne in August 1714; her son became George I and the pro-Hanoverian Whigs controlled government for the next 30 years. 
 Question: What happened first, 1701 Act of Settlement or 1707 Act of Union?
Output: 1701 act of settlement
Context: Where do dogs come from? Gray wolves are their ancestors. Scientists are pretty consistent about that. And researchers have suggested that dogs' origins can date back to Europe, the Near East, Siberia and South China. Central Asia is the newest and best candidate, according to a large study of dogs from around the world. Laura M. Shannon and Adam R. Boyko at Cornell University, and an international group of other scientists, studied not only purebred dogs, but also street or village dogs. Dr. Shannon analyzed three different kinds of DNA, Dr. Boyko said, the first time this has been done for such a large and diverse group of dogs from 38 countries. And that led them to Central Asia as the place of origin for dogs in much the same way that genetic studies have located the origin of modern humans in East Africa. The analysis, Dr. Boyko said, pointed to Central Asia, as the place where "all the dogs alive today" come from. The data did not allow precise dating of the origin, he said, but showed it occurred at least 15,000 years ago. Greger Larson of Oxford University, who is leading a large international effort to analyze ancient DNA from fossilized bones, said he was impressed by the study. "It's really great to see not just the number of street dogs, but also the geographic breadth and the number of remote locations where the dogs were sampled," he said in an email. He also praised the sampling of different kinds of DNA and the analytic methods. Dr. Larson, who was not involved with the study, said he thought the Central Asia finding required further testing. He said he suspected that the origins of modern dogs were "extremely messy" and that no amount of sampling of living populations will be definitive. He said a combination of studies of modern and ancient DNA is necessary. 
 Question: Who wasn't engaged in the study of dogs' origins?
Output: greger larson
Context: Activation of the superoxide-producing NADPH oxidase Nox1 requires both the organizer protein Noxo1 and the activator protein Noxa1. Here we describe an alternative splicing form of Noxo1, Noxo1gamma, which is expressed in the testis and fetal brain. The Noxo1gamma protein contains an additional five amino acids in the N-terminal PX domain, a phosphoinositide-binding module; the domain plays an essential role in supporting superoxide production by NADPH oxidase (Nox) family oxidases including Nox1, gp91(phox)/Nox2, and Nox3, as shown in this study. The PX domain isolated from Noxo1gamma shows a lower affinity for phosphoinositides than that from the classical splicing form Noxo1beta. Consistent with this, in resting cells, Noxo1gamma is poorly localized to the membrane, and thus less effective in activating Nox1 than Noxo1beta, which is constitutively present at the membrane. On the other hand, cell stimulation with phorbol 12-myristate 13-acetate (PMA), an activator of Nox1-3, facilitates membrane translocation of Noxo1gamma; as a result, Noxo1gamma is equivalent to Noxo1beta in Nox1 activation in PMA-stimulated cells. The effect of the five-amino-acid insertion in the Noxo1 PX domain appears to depend on the type of Nox; in activation of gp91(phox)/Nox2, Noxo1gamma is less active than Noxo1beta even in the presence of PMA, whereas Noxo1gamma and Noxo1beta support the superoxide-producing activity of Nox3 to the same extent in a manner independent of cell stimulation. 
 Question: Which NADPH oxidase family member requires interaction with NOXO1 for function?
Output: nadph oxidase 1
Context: Activation of the superoxide-producing NADPH oxidase Nox1 requires both the organizer protein Noxo1 and the activator protein Noxa1. Here we describe an alternative splicing form of Noxo1, Noxo1gamma, which is expressed in the testis and fetal brain. The Noxo1gamma protein contains an additional five amino acids in the N-terminal PX domain, a phosphoinositide-binding module; the domain plays an essential role in supporting superoxide production by NADPH oxidase (Nox) family oxidases including Nox1, gp91(phox)/Nox2, and Nox3, as shown in this study. The PX domain isolated from Noxo1gamma shows a lower affinity for phosphoinositides than that from the classical splicing form Noxo1beta. Consistent with this, in resting cells, Noxo1gamma is poorly localized to the membrane, and thus less effective in activating Nox1 than Noxo1beta, which is constitutively present at the membrane. On the other hand, cell stimulation with phorbol 12-myristate 13-acetate (PMA), an activator of Nox1-3, facilitates membrane translocation of Noxo1gamma; as a result, Noxo1gamma is equivalent to Noxo1beta in Nox1 activation in PMA-stimulated cells. The effect of the five-amino-acid insertion in the Noxo1 PX domain appears to depend on the type of Nox; in activation of gp91(phox)/Nox2, Noxo1gamma is less active than Noxo1beta even in the presence of PMA, whereas Noxo1gamma and Noxo1beta support the superoxide-producing activity of Nox3 to the same extent in a manner independent of cell stimulation. 
 Question: Which NADPH oxidase family member requires interaction with NOXO1 for function?
Output: nicotinamide adenine dinucleotide phosphate-oxidase 1
Context: Activation of the superoxide-producing NADPH oxidase Nox1 requires both the organizer protein Noxo1 and the activator protein Noxa1. Here we describe an alternative splicing form of Noxo1, Noxo1gamma, which is expressed in the testis and fetal brain. The Noxo1gamma protein contains an additional five amino acids in the N-terminal PX domain, a phosphoinositide-binding module; the domain plays an essential role in supporting superoxide production by NADPH oxidase (Nox) family oxidases including Nox1, gp91(phox)/Nox2, and Nox3, as shown in this study. The PX domain isolated from Noxo1gamma shows a lower affinity for phosphoinositides than that from the classical splicing form Noxo1beta. Consistent with this, in resting cells, Noxo1gamma is poorly localized to the membrane, and thus less effective in activating Nox1 than Noxo1beta, which is constitutively present at the membrane. On the other hand, cell stimulation with phorbol 12-myristate 13-acetate (PMA), an activator of Nox1-3, facilitates membrane translocation of Noxo1gamma; as a result, Noxo1gamma is equivalent to Noxo1beta in Nox1 activation in PMA-stimulated cells. The effect of the five-amino-acid insertion in the Noxo1 PX domain appears to depend on the type of Nox; in activation of gp91(phox)/Nox2, Noxo1gamma is less active than Noxo1beta even in the presence of PMA, whereas Noxo1gamma and Noxo1beta support the superoxide-producing activity of Nox3 to the same extent in a manner independent of cell stimulation. 
 Question: Which NADPH oxidase family member requires interaction with NOXO1 for function?
Output: nox1
Context: Self-report questionnaires are frequently used to identify PTSD among U.S. military personnel and Veterans. Two common scoring methods used to classify PTSD include: (1) a cut score threshold and (2) endorsement of PTSD symptoms meeting DSM-IV-TR symptom cluster criteria (SCM). A third method requiring a cut score in addition to SCM has been proposed, but has received little study. The current study examined the diagnostic accuracy of three scoring methods for the Davidson Trauma Scale (DTS) among 804 Afghanistan and Iraq war-era military Service Members and Veterans. Data were weighted to approximate the prevalence of PTSD and other Axis I disorders in VA primary care. As expected, adding a cut score criterion to SCM improved specificity and positive predictive power. However, a cut score of 68-72 provided optimal diagnostic accuracy. The utility of the DTS, the role of baseline prevalence, and recommendations for future research are discussed. 
 Question: Symptoms of which disorder are evaluated with the Davidson Trauma Scale?
Output: ptsd
Context: Self-report questionnaires are frequently used to identify PTSD among U.S. military personnel and Veterans. Two common scoring methods used to classify PTSD include: (1) a cut score threshold and (2) endorsement of PTSD symptoms meeting DSM-IV-TR symptom cluster criteria (SCM). A third method requiring a cut score in addition to SCM has been proposed, but has received little study. The current study examined the diagnostic accuracy of three scoring methods for the Davidson Trauma Scale (DTS) among 804 Afghanistan and Iraq war-era military Service Members and Veterans. Data were weighted to approximate the prevalence of PTSD and other Axis I disorders in VA primary care. As expected, adding a cut score criterion to SCM improved specificity and positive predictive power. However, a cut score of 68-72 provided optimal diagnostic accuracy. The utility of the DTS, the role of baseline prevalence, and recommendations for future research are discussed. 
 Question: Symptoms of which disorder are evaluated with the Davidson Trauma Scale?
Output: post-traumatic stress disorder
Context: * Cliffs of Moher, Ireland Stretching for five miles along Ireland5s western coast, the Cliffs of Moher are a sight more than 300 million years in the making. At their highest, the cliffs soar an impressive 702 feet above the Atlantic Ocean, offering the million visitors who visit each year incredible views sure to leave hearts racing both from the beauty and the height. * White Cliffs of Dover,UK These famous cliffs along England's south-eastern coast are as rich in history as they are in beauty. They stand tall along the Strait of Dover, separating England from France and continental Europe. During World War I, the first bomb to hit the UK fell in Dover, and it served as a prominent location during WWII as well. And nowadays, the city is the best known for the beauty of its chalky white cliffs. * Mount Thor, Canada The name Mount Thor may inspire fear or respect -- as well it should, considering this is the steepest, tallest cliff in the world. Thor reaches an astonishing 4?101 feet above sea level, and the utter greatness of its vertical incline kept it from being successfully gone up until 1965. Today,it remains a challenging and popular place for rock climbers. ' * Cliffs of Etretat,France Located along France's Alabaster Coast, these cliffs offer more than just steep walls. Climb to the top and you'll have views of arched rock formations, as well as scenery that inspired the famous painter Claude Monet. At various points along the cliffs580-mile stretch, you can spot natural sculptures that are said to resemble an elephant, among other things. 
 Question: The beauty of the chalky white cliffs can be enjoyed by visiting .
Output: dover
Context: As of the census of 2000, there were 120,546 people, 41,668 households, and 32,292 families residing in the county. The population density was 262 people per square mile (101/km). There were 43,903 housing units at an average density of 95 per square mile (37/km). The racial makeup of the county was 68.51% Race (United States Census), 26.06% Race (United States Census) or Race (United States Census), 0.75% Race (United States Census), 1.82% Race (United States Census), 0.06% Race (United States Census), 0.72% from Race (United States Census), and 2.08% from two or more races. 2.26% of the population were Race (United States Census) or Race (United States Census) of any race. 11.6% were of german people, 10.8% irish people, 10.2% english people, 9.3% American and 5.3% italian people ancestry. 
 Question: Which group from the census is larger: german or english?
Output: german
Context: ''The Lighthouse's Tale'' is a song by progressive bluegrass band Nickel Creek, taken from their debut album, Nickel Creek, released in 2001. 
 Question: Who is the performer of The Lighthouse's Tale?
Output: nickel creek
Context: The nuclear factor of activated T cells (NFAT) group of transcription factors is retained in the cytoplasm of quiescent cells. NFAT activation is mediated in part by induced nuclear import. This process requires calcium-dependent dephosphorylation of NFAT caused by the phosphatase calcineurin. The c-Jun amino-terminal kinase (JNK) phosphorylates NFAT4 on two sites. Mutational removal of the JNK phosphorylation sites caused constitutive nuclear localization of NFAT4. In contrast, JNK activation in calcineurin-stimulated cells caused nuclear exclusion of NFAT4. These findings show that the nuclear accumulation of NFAT4 promoted by calcineurin is opposed by the JNK signal transduction pathway. 
 Question: Which calcium/calmodulin dependent protein phosphatase is involved in the activation of the family of NFAT transcription factors (Nuclear Factors of Activated T cells)?
Output: can
Context: The nuclear factor of activated T cells (NFAT) group of transcription factors is retained in the cytoplasm of quiescent cells. NFAT activation is mediated in part by induced nuclear import. This process requires calcium-dependent dephosphorylation of NFAT caused by the phosphatase calcineurin. The c-Jun amino-terminal kinase (JNK) phosphorylates NFAT4 on two sites. Mutational removal of the JNK phosphorylation sites caused constitutive nuclear localization of NFAT4. In contrast, JNK activation in calcineurin-stimulated cells caused nuclear exclusion of NFAT4. These findings show that the nuclear accumulation of NFAT4 promoted by calcineurin is opposed by the JNK signal transduction pathway. 
 Question: Which calcium/calmodulin dependent protein phosphatase is involved in the activation of the family of NFAT transcription factors (Nuclear Factors of Activated T cells)?
Output: calcineurin
Context: The nuclear factor of activated T cells (NFAT) group of transcription factors is retained in the cytoplasm of quiescent cells. NFAT activation is mediated in part by induced nuclear import. This process requires calcium-dependent dephosphorylation of NFAT caused by the phosphatase calcineurin. The c-Jun amino-terminal kinase (JNK) phosphorylates NFAT4 on two sites. Mutational removal of the JNK phosphorylation sites caused constitutive nuclear localization of NFAT4. In contrast, JNK activation in calcineurin-stimulated cells caused nuclear exclusion of NFAT4. These findings show that the nuclear accumulation of NFAT4 promoted by calcineurin is opposed by the JNK signal transduction pathway. 
 Question: Which calcium/calmodulin dependent protein phosphatase is involved in the activation of the family of NFAT transcription factors (Nuclear Factors of Activated T cells)?
Output: phosphatase 2b
Context: The apolipoprotein E type 4 allele is a susceptibility gene for late-onset Alzheimer's disease. Apolipoprotein E is found in neurons, some of which contain paired helical filaments made of the microtubule-associated protein tau. Previous studies have demonstrated that the apoE3 isoform, but not the apoE4 isoform, binds tau with high avidity. Because the microtubule-associated protein MAP2c also effects microtubule assembly and stability, we examined interactions between apoE isoforms and MAP2c. Similar to the tau-binding results, apoE3, but not apoE4, bound MAP2c. Binding was detectable down to 10(-9) M MAP2c and 10(-8) M apoE3. Isoform-specific interactions of apoE with the microtubule-associated proteins MAP2c and tau might affect intracellular maintenance of microtubules and could contribute to a time-dependent pathogenesis of Alzheimer's disease. 
 Question: Which ApoE isoform is associated with atherosclerosis and Alzheimer's disease?
Output: apoe4 isoform
Context: The apolipoprotein E type 4 allele is a susceptibility gene for late-onset Alzheimer's disease. Apolipoprotein E is found in neurons, some of which contain paired helical filaments made of the microtubule-associated protein tau. Previous studies have demonstrated that the apoE3 isoform, but not the apoE4 isoform, binds tau with high avidity. Because the microtubule-associated protein MAP2c also effects microtubule assembly and stability, we examined interactions between apoE isoforms and MAP2c. Similar to the tau-binding results, apoE3, but not apoE4, bound MAP2c. Binding was detectable down to 10(-9) M MAP2c and 10(-8) M apoE3. Isoform-specific interactions of apoE with the microtubule-associated proteins MAP2c and tau might affect intracellular maintenance of microtubules and could contribute to a time-dependent pathogenesis of Alzheimer's disease. 
 Question: Which ApoE isoform is associated with atherosclerosis and Alzheimer's disease?
Output: apolipoprotein e4 isoform
Context: Her daughter Ariadne was Empress consort of first Zeno and then Anastasius I. Verina was the maternal grandmother of Leo II. 
 Question: What was Verina's child's name?
Output: ariadne
Context: Coming off their Monday night road win over the Saints, the Vikings went home for a Week 6 NFC North duel with the Detroit Lions. In the first quarter, the Vikes got an early lead as Lions QB Dan Orlovsky unintentionally ran out of the back of his own end zone, giving Minnesota a safety which Orlovsky didn't know why the whistles were blown. In the second quarter, Detroit got the lead as kicker Jason Hanson got a 40-yard field goal. In the third quarter, the Lions increased their lead as Orlovsky completed a 12-yard TD pass to WR Calvin Johnson. The Vikings answered with QB Gus Frerotte completing an 86-yard TD pass to WR Bernard Berrian. In the end of the fourth quarter, the Vikes got in field goal range due to a controversial pass interference call on Leigh Bodden. The Vikes sealed the win with kicker Ryan Longwell nailing the game-winning 26-yard field goal. 
 Question: Which QB threw the longest TD pass?
Output: frerotte
Context: Fish species are expected to shrink in size by up to 24% because of global warming, say scientists. The scientists argue that failure to control greenhouse gas emissions will have a greater effect on marine ecosystems than previously thought. Previous research has suggested that changing ocean temperatures would affect both the distribution and the reproductive abilities of many species of fish. This new work suggests that fish size would also be heavily affected. The researchers built a model to see how fish would react to lower levels of oxygen in the water. As ocean temperatures increase, so do the body temperatures of fish. But, according to lead author, Dr William Cheung, from the University of British Columbia, the lower level of oxygen in the water is key. Warmer waters could decrease ocean oxygen levels and greatly reduce fish body weight. On the other hand, rising temperatures directly increase the metabolic rate of the fish's body function. This leads to an increase in oxygen demand for normal body activities. So the fish will run out of oxygen for growth at a smaller body size. The research team also used its model to predict fish movements as a result of warming waters. The group believes that most fish populations will move towards the Earth's poles at a rate of up to 35km per decade. "So in, say, the North Sea," says Dr Cheung," one would expect to see more smaller-body fish from tropical waters in the future." Taking these factors into consideration, the research team concludes that fish body size will shrink between 14% and 24%, with the largest decreases in the Indian and Atlantic oceans. When compared with actual observations of fish sizes, the model seems to _ what's actually happening in the seas. The researchers looked at two case studies involving North Atlantic cod and haddock. They found that recorded data on these fish showed greater decreases in body size than the models had predicted. Dr Alan Baudron, from the University of Aberdeen, UK, believes smaller-sized fish could seriously affect the ability of fish to reproduce. "Smaller fish produce fewer and smaller eggs which could affect the reproductive potential of fish stocks," he said. 
 Question: What is the key factor making the fish smaller now?
Output: the lower level of oxygen in the water.
Context: Sir Charles Nicholas Mander, 4th Baronet (born 23 March 1950) is a British baronet. 
 Question: What was the title that Nicholas Mander held?
Output: baronet
Context: Psychiatric disorders have a great impact on morbidity and mortality. Genotype-phenotype resources for psychiatric diseases are key to enable the translation of research findings to a better care of patients. PsyGeNET is a knowledge resource on psychiatric diseases and their genes, developed by text mining and curated by domain experts. We present psygenet2r, an R package that contains a variety of functions for leveraging PsyGeNET database and facilitating its analysis and interpretation. The package offers different types of queries to the database along with variety of analysis and visualization tools, including the study of the anatomical structures in which the genes are expressed and gaining insight of gene's molecular function. Psygenet2r is especially suited for network medicine analysis of psychiatric disorders. The package is implemented in R and is available under MIT license from Bioconductor ([Link] juanr.gonzalez@isglobal.org or laura.furlong@upf.edu. Supplementary data are available at Bioinformatics online. 
 Question: Which R/Bioconductor package has been developed for the analysis of psychiatric disease genes?
Output: psygenet2r
Context: Dementia is a frequent complication of idiopathic parkinsonism or PD, usually occurring later in the protracted course of the illness. The primary site of neuropathologic change in PD is the substantia nigra, but the neuropathologic and molecular basis of dementia in PD is less clear. Although Alzheimer's pathology has been a frequent finding, recent advances in immunostaining of alpha-synuclein have suggested the possible importance of cortical Lewy bodies (CLBs) in the brains of demented patients with PD. The brains of 22 demented and 20 nondemented patients with a clinical and neuropathologic diagnosis of PD were evaluated with standard neuropathologic techniques. In addition, CLBs and dystrophic neurites were identified immunohistochemically with antibodies specific for alpha-synuclein and ubiquitin; plaques and tangles were identified by staining with thioflavine S. Associations between dementia status and pathologic markers were tested with logistic regression. CLBs positive for alpha-synuclein are highly sensitive (91%) and specific (90%) neuropathologic markers of dementia in PD and slightly more sensitive than ubiquitin-positive CLBs. They are better indicators of dementia than neurofibrillary tangles, amyloid plaques, or dystrophic neurites. CLBs detected by alpha-synuclein antibodies in patients with PD are a more sensitive and specific correlate of dementia than the presence of Alzheimer's pathology, which was present in a minority of the cases in this series. 
 Question: Against which protein is the antibody used for immonostaining of Lewy bodies raised?
Output: alpha-synuclein
Context: Recently, I came across an interesting article on the differences between British English and American English. I had a lot of fun reading it and thinking of as many differences as I could as an American. Their cars have "bonnets ",while ours have "hoods". They park their cars in a "car park" while we leave our in a "parking lot". Our "cookies" are their "biscuits", while their "rubbers" are our "erasers". Then there are the food words. Would you want to eat something called "Toad in the Hole" or "Bangers and Mash" or "Spotted Dick"? I'm here to report they are all very tasty. There are American equivalents , of course. We've got "Shoofly Mud Pie". What they call "crisps" is what we call "potato chips" and when we ask for "chips" in England we will get what we know at home in America as "French fries". They find it hysterical that we call the "toilet" the "bathroom" and they really double over with laughter when we ask for the "restroom". American ladies in England who ask for the "little girl's room" or the "power room" will be met with blank stares. A "fag" is a "cigarette" in the UK, which can lead to endless confusion for British visitors looking for a cigarette in America. Americans on the other hand are endlessly confused by English signs put up over doorways saying "Way Out". We Americans walk on the sidewalk not the pavement. "Pavement" in America is the actual cement the sidewalk is made of. 
 Question: What do British people call French fries?
Output: chips.
Context: Paul MacEwan (born April 8, 1943) is a former politician in Cape Breton Island, Nova Scotia, Canada, and long-time member of the Nova Scotia House of Assembly. 
 Question: What is the position of Paul MacEwan?
Output: member of the nova scotia house of assembly
Context: A 29-year-old man with a history of elevated creatine kinase and necrotizing myopathy was reviewed. Prominent red cell acanthocytosis in association with reduced Kell antigen expression was present, findings consistent with the McLeod syndrome. Investigation of the patient's XK gene revealed a novel TGG- to-TAG transition at position 1023 in exon 3. This point mutation creates an in-frame stop codon (W314X), and predicts a truncated XK protein of 313 amino acids, compared with 444 amino acids in the normal XK protein. The mutation was not identified in the patient's mother or sister indicating that this mutation was spontaneous. 
 Question: Mutation of which gene is associated with McLeod syndrome?
Output: xk
Context: Louis Philippe I (6 October 1773 -- 26 August 1850) was King of the French from 1830 to 1848 as the leader of the Orleanist party. 
 Question: What nationality was Louis Philippe I?
Output: french
Context: Ilich Ramirez Sanchez (pronounced: (ilit ramies santes); born October 12, 1949), also known as Carlos the Jackal, is a Venezuelan terrorist currently serving a life sentence in France for the 1975 murder of an informant for the French government and two French counter-intelligence agents. 
 Question: Which crime led to the conviction of Carlos the Jackal?
Output: murder
Context: Huruma Estate is a residential estate located in the northeast of Nairobi, the capital of Kenya. 
 Question: What country is home to Huruma?
Output: kenya
Context: The Broadgate Tower was designed by Skidmore, Owings & Merrill and developed by British Land. 
 Question: Who was the architect involved with Broadgate Tower?
Output: skidmore, owings & merrill
Context: Coming off their win over the Browns, the Bears stayed at home for a Week 9 duel with the Arizona Cardinals. Chicago would trail early in the first quarter as Cardinals quarterback Kurt Warner hooked up with wide receiver Larry Fitzgerald on an 11-yard touchdown pass. The Bears would answer as quarterback Jay Cutler competed a 33-yard touchdown pass to tight end Greg Olsen, but Arizona came right back as Warner hooked up with tight end Ben Patrick on a 6-yard touchdown pass. Chicago would find themselves in a huge deficit in the second quarter as Warner completed a 17-yard touchdown pass to Fitzpatrick and a 15-yard touchdown pass to tight end Anthony Becht, followed by kicker Neil Rackers nailing a 43-yard field goal. The Cardinals would add onto their lead as Rackers booted a 30-yard field goal in the third quarter. The Bears tried to rally in the fourth quarter as Cutler connected with Olsen on a 3-yard and a 20-yard touchdown pass, but Arizona pulled away with Warner completing a 4-yard touchdown pass to wide receiver Steve Breaston. 
 Question: Which player caught the most touchdown passes?
Output: greg olsen
Context: CADASIL is a cerebrovascular disease caused by mutations in the NOTCH3 gene. Most mutations result in a gain or loss of cysteine residue in one of the 34 epidermal growth factor-like repeats in the extracellular domain of the Notch3 protein, thus sparing the number of cysteine residues. To date, more than 130 different mutations in the NOTCH3 gene have been reported in CADASIL patients, of which 95% are missense point mutations. Many polymorphisms have also been identified in the NOTCH3 coding sequence, some of them leading to amino acid substitutions. The aim of the present study was to analyze the NOTCH3 gene in a large group of patients affected by leukoencephalopathy and to investigate the presence of genetic variants. The molecular analysis revealed several nucleotide alterations. In particular, we identified 20 different mutations, 22 polymorphisms, and 8 genetic variants of unknown pathological significance never reported previously. We hope that this NOTCH3 gene mutational analysis, performed in such a significant number of unrelated and related patients affected by leukoencephalopathy, will help in molecular screening for the NOTCH3 gene, thus contributing to enlargement of the NOTCH3 gene variation database. 
 Question: Which amino acid residue appears mutated in most of the cases reported with cadasil syndrome?
Output: cysteine
Context: Infective embolic retinopathy as a sequela of bacterial endocarditis is described in a 31-year-old woman with mitral valve prolapse. The infective organism, Corynebacterium minutissimum, has not been previously found to cause ocular or multisystem diseases. It is a common mucocutaneous inhabitant which causes erythrasma. In our case report both ocular involvement and septicaemia were present. The infection was confirmed by positive serial blood cultures. Mitral valve prolapse was confirmed by echocardiography. On clinical examination the retinopathy consisted of white intraretinal lesions which resolved with antibiotic therapy. By fluorescein angiography focal areas of hypofluorescence corresponding to the white fundus lesions were present. Optic disc oedema was also seen. 
 Question: Which bacteria causes erythrasma?
Output: corynebacterium minutissimum
Context: Sandford-on-Thames is a village and Parish Council beside the River Thames in Oxfordshire just south of Oxford. 
 Question: Which is the body of water by Sandford-on-Thames?
Output: river thames
Context: Zach Conroy and Celeste Mercier are the hottest couple on and off the ice until a nasty spill knocks Celeste out of competition. With their dreams of gold medals put in ice and their romance chilling as a result, Zach has to find another partner for the championship in Paris. And fast. In glides Alejandra Alex Delgado, a beautiful, tough talking hockey player with fierce moves and a fearless skating style. Zachs willing to give her a chance, but his coach, Bryan quits in a huff to train Zachs biggest rivals, Cindy Halgyord and Jason Bright. That leaves Zach with a newbie partner and no coach until he convinces former figure skating champ Jackie Dorsey to step in. She puts Zach and Alex through their paces, but the hardest trick of all is keeping them focused on practice and not each other as they bicker and struggle with a growing attraction both on and off the ice. Jackie knows these kids are fire and ice, and sees the chemistry between them. She also knows that if they cant get it together, theyll set the skating world on fire. That is, if the heat between them doesnt cause a total meltdown. With the competition fierce and the stakes higher than ever, the only way Zach and Alex can win is by putting aside their feelings and pulling out a secret weapon: the deadly Pamchecko jump. But is it worth the risk? Can Zach rise above the past and his history of injuring partners? And can Alex prove that shes got the moves to match her passion? It all comes down to the biggest moment of their lives when they learn that sometimes on the ice and in life youve got to risk it all. 
 Question: Where did the two ablemake it to?
Output: championship in paris