Note: This synopsis is consistent with the novel in its later forms (1946 and subsequent editions) but differs in detail from the original 1928 text as transcribed at Project Gutenberg. There were significant changes between the 1928 magazine publication and the 1946 hardcover, and between the early hardcovers and the late 1950s and later paperback editions.
The Skylark of Space is the first book of the Skylark series and pits the idealistic protagonist, Dick Seaton, against the mercantile antagonist Marc "Blackie" DuQuesne.
At the beginning of the story, Seaton accidentally discovers a workable space drive in combining pure copper with a newly discovered [fictional] element "X" (suggested to be a stable transactinide element in the platinum group) in solution. Having failed to re-create the effect, Seaton realizes that the missing component is a field generated by DuQuesne's particle accelerator, and thereafter sets up a business with his millionaire friend, Martin Crane, to build a spaceship. DuQuesne conspires to sabotage Seaton's spaceship and build his own from Seaton's plans, which he uses to kidnap Seaton's fianc e, Dorothy Vaneman, to exchange for the "X". In the resulting fight, DuQuesne's ship is accidentally set to full acceleration on an uncontrolled trajectory, until the copper 'power bar' is exhausted at a vast distance from Earth's solar system. Using an "Object Compass" that once locked on an object, always points toward that object, Seaton and Crane follow DuQuesne in their own spaceship (the eponymous Skylark) to rescue Dorothy and her fellow-hostage, Margaret "Peg" Spencer, until the Skylark discovers DuQuesne's ship derelict in orbit around a massive dead star (resembling a cold neutron star). Having obtained the hostages, Seaton extracts a promise from DuQuesne to "act as one of the party until they get back to Earth", in which relationship they leave orbit and travel further in search of additional fuel.
On an Earthlike exoplanet, they obtain "X" from an outcrop almost purely of that mineral; then leave that planet in search of copper. Following an encounter with a "Disembodied Intelligence" (Star Trek's "Q" would later show similar attributes), they enter a cluster of stars nicknamed  The Green System  and locate a planet having copper sulfate oceans. On the Earth-like "Osnome", they befriend the rulers of Mardonale, one of the two factions of the Osnomian natives. When the Mardonalian ruler attempts to betray Seaton and his friends, they find allies in Prince Dunark (a crown-prince of Mardonale's rival "Kondal") and his consort Princess Sitar, whom they later assist in destroying Mardonale. In gratitude, the Kondalians make new copper "power bars" and rebuild the Skylark as Skylark Two, with new weapons known to Kondalian science. Thereafter Seaton's marriage to Dorothy, and Crane's to Margaret, are solemnized by the Kondalian monarchy, and Seaton himself declared nominal "Overlord" of Kondal. The Skylark then returns to Earth, laden with jewels, platinum, radium, and a plenitude of "X"; but near Earth, DuQuesne leaves the Skylark by parachute, and the story ends with the Skylark's landing on Crane's Field.
Output: What element makes workable space drive combining with pure copper?