Question: What are the symptoms of Castleman's disease? Passage 1:As far back as 1854, the famous glass exhibition building known as The Crystal Palace had been relocated from Hyde Park, London and rebuilt in an area of South London next to Sydenham Hill. This area was renamed Crystal Palace including the park surrounding the site where various sports facilities were built. The earliest known Crystal Palace football team first played here in 1861 as an amateur outfit. They went on to become founder members of the Football Association and competed in the very first FA Cup competition reaching the semi-finals where they were eliminated by the Royal Engineers in a replay after the first game ended goalless. The team also played in the FA Cup in the next four seasons before disappearing from historical records after a 0–3 defeat to eventual winners Wanderers in the second round of the 1875–76 FA Cup. In 1895, the Football Association adopted a new permanent home for the FA Cup Final which was to be played at the sports stadium situated inside the historic grounds of the Palace. With the owners also reliant on tourist activity for their income, they sought fresh attractions for the venue, and founded the London County Cricket Club of W. G. Grace before turning their attention to football.
 Passage 2:The first known settlers in the area of modern Nashville were Native Americans who arrived in the region by at least 13,000 BC during the Paleoindian period of regional prehistory. For millennia the descendants of these first Tennesseans continued to live along the river terraces and uplands overlooking the Cumberland River, leaving behind a dense archaeological record spanning the Paleoindian, Archaic, Woodland, and Mississippian periods. The final prehistoric Native American culture to inhabit what would become Nashville was a regional manifestation of the Mississippian Culture known as Middle Cumberland Mississippian, identified by archaeologists based on the specific combination of burial practices, artistic style, and ceramic styles. Recent studies suggest that Middle Cumberland Mississippian culture may be the result of interactions between local populations and outsiders from the American Bottom who moved into the western portion of the Nashville Basin around AD 1000, settling at the site of Mound Bottom. The archaeological footprint of the Middle Cumberland Mississippian culture appears throughout Nashville as the many platform mounds, extensive stone box cemeteries, palisaded villages, and small prehistoric farmsteads that have been destroyed by antiquarian scholars, relic hunters, and urban development. All archaeological evidence for Mississippian culture appears to vanish from the Nashville area by around AD 1475–1500. Archaeologists believe this regional collapse may have been the result of extreme pressures brought on by rapid population growth and dwindling resource availability following prolonged droughts leading to increased occurrences of disease, nutritional deficiencies, and warfare.
 Passage 3:Herpesviruses are a third group of common cancer-causing viruses. Two types of herpesviruses have been associated with cancer: the Epstein–Barr virus (EBV) and human herpesvirus 8 (HHV-8). EBV appears to cause all nonkeratinizing nasopharyngeal carcinomas and some cases of lymphoma, including Burkitt's lymphoma—the association is especially strong in Africa—and Hodgkin's disease. EBV has also been found in a variety of other types of cancer cells, although its role in causing these other cancers is not well established. KSHV/HHV-8 causes all cases of Kaposi's sarcoma, and has been found in some cases of a cancer-related condition called Castleman's disease. Studies involving other kinds of cancer, particularly prostate cancer, have been inconsistent. Both of these herpesviruses are commonly found in cancerous cells of primary effusion lymphoma. Herpesviruses also cause cancer in animals, especially leukemias and lymphomas.

Output: 3