Question: What year did the 15th century chronicler and antiquary that documented Hotwells springs die? Passage 1:Von Economo, in his studies, noticed that lesions in the connection between the midbrain and the diencephalon caused prolonged sleepiness and therefore proposed the idea of an ascending arousal system. During the past few decades major ascending pathways have been discovered with located neurons and respective neurotransmitters. This pathway divides into two branches: one that ascends to the thalamus and activates the thalamus relay neurons, and another one that activates neurons in the lateral part of the hypothalamus and the basal forebrain, and throughout the cerebral cortex. The cell group involved in the first pathway is an acetylcholine-producing cell group called pedunculopontine and laterodorsal tegmental nucleus(PPT/LDT). These neurons play a crucial role in bridging information in between the thalamus and the cerebral cortex. These neurons have high activation during wakefulness and during REM sleep and a low activation during NREM sleep. The second branch originates from monoaminorgenic neurons. These neurons are located in the locus coeruleus, dorsal and median raphe nuclei, ventral periaqueductal grey matter, and tuberomammillary nucleus. Each group produces a different neurotransmitter. The neurons in the locus coeruleus produce noradrenaline, as fore the neurons in the dorsal and median raphe nuclei, ventral periaqueductal grey matter, and tuberomammillary nucleus produce serotonin, dopamine and histamine respectively. They then project onto the hypothalamic peptidergic neurons, which contain melanin-concentrated hormones or orexin, and basal forebrain neurons which contain GABA and acetylcholine. These neurons then project onto the cerebral cortex. It has also been discovered that lesions to this part of the brain cause prolonged sleep or may produce coma.
 Passage 2:Born in Montreal, Quebec, Berry began his junior hockey career with the Peterborough Petes of the OHA before deciding to attend Sir George Williams University (now Concordia University) in Montreal where he would play three years of collegiate hockey in the OQAA (now CIS). In 1966 Berry joined Canada's National Hockey Team and was later signed by the Montreal Canadiens to his first professional contract in 1968 at age 25. With the Canadiens having a deep roster at left wing, Berry would only manage to suit up for two games with the Canadiens in 1968-69. He spent the following year playing in the AHL for the Montreal Voyageurs and the Canadiens eventually sold his rights to the Los Angeles Kings in 1970 giving him a better opportunity to earn a spot on an NHL roster. Berry joined the Los Angeles Kings the following year in 1970-71 and registered 63 points in 73 games in his rookie season, placing him only 9 points back of eventual Calder Trophy winner Gil Perreault of the Buffalo Sabres. In 1972-73 Berry scored a career high 36 goals with the Kings and was selected to play in his first NHL All-Star game on January 30, 1973 at Madison Square Garden in New York. Berry was selected to play in the All-Star game again the following year at the Chicago Stadium. He finished his NHL career with 350 points in 541 regular season games.
 Passage 3:Hotwells takes its name from the hot springs which bubble up through the rocks of the Avon Gorge underneath the Clifton Suspension Bridge. The springs were documented in 1480 by William Worcester, the 15th century chronicler and antiquary. He described the waters as being milky and as warm as those at Bath. In 1692 the Society of Merchant Venturers leased the springs and a pump room was built. The pump room of 1696 was demolished and replaced by Hotwells House in 1816 which was itself demolished when the river was widened in 1867. In the Georgian era, Hotwells was developed as a spa including the building of Dowry Square in an attempt to compete with Bath. Many visitors came, including the diarist John Evelyn and the travel writer Celia Fiennes, who hunted for Bristol Diamonds in the gorge. The Somerset historian John Collinson came to Hotwells in 1793 seeking recovery from an unspecified lingering illness and died there on 27 August 1793. 

Output: 3