Question: How long was the reign of Minbya's grandfather? Passage 1:The fight-or-flight response involves nervous impulses which result in hormone secretions into the bloodstream. When a horse reacts to a threat, it may initially "freeze" in preparation to take flight. The fight-or-flight reaction begins in the amygdala, which triggers a neural response in the hypothalamus. The initial reaction is followed by activation of the pituitary gland and secretion of the hormone ACTH. The adrenal gland is activated almost simultaneously and releases the neurotransmitters epinephrine (adrenaline) and norepinephrine (noradrenaline). The release of chemical messengers results in the production of the hormone cortisol, which increases blood pressure and blood sugar, and suppresses the immune system. Catecholamine hormones, such as epinephrine and norepinephrine, facilitate immediate physical reactions associated with a preparation for violent muscular action. The result is a rapid rise in blood pressure, resulting in an increased supply of oxygen and glucose for energy to the brain and skeletal muscles, the most vital organs the horse needs when fleeing from a perceived threat. However, the increased supply of oxygen and glucose to these areas is at the expense of "non-essential" flight organs, such as the skin and abdominal organs.
 Passage 2:Thado Minbya was born Rahula to Princess Soe Min Kodawgyi of Sagaing and Viceroy Thado Hsinhtein of Tagaung in 1345. From his mother's side, he was a grandson of King Saw Yun, the founder of the Sagaing Kingdom, and nephew of then reigning king Kyaswa as well as a great grandson of King Thihathu of Pinya and King Kyawswa of Pagan. From his father's side, he was descended from a line of hereditary rulers of Tagaung from the House of Thado. According to British colonial period scholarship, his father was an ethnic Shan and his mother was mostly Shan; however some have argued that no extant chronicle or archaeological evidence supports the conjecture. The prince had two younger sisters: Shin Saw Gyi and Saw Omma. His father died soon after the birth of Saw Omma. His mother remarried to Thihapate, a grandnephew of Queen Pwa Saw of Pagan. In 1352, Thihapate became king of Sagaing.
 Passage 3:Corals, including some major extinct groups Rugosa and Tabulata, have been important reef builders through much of the Phanerozoic since the Ordovician Period. However, other organism groups, such as calcifying algae, especially members of the red algae Rhodophyta, and molluscs (especially the rudist bivalves during the Cretaceous Period) have created massive structures at various times. During the Cambrian Period, the conical or tubular skeletons of Archaeocyatha, an extinct group of uncertain affinities (possibly sponges), built reefs. Other groups, such as the Bryozoa have been important interstitial organisms, living between the framework builders. The corals which build reefs today, the Scleractinia, arose after the Permian–Triassic extinction event that wiped out the earlier rugose corals (as well as many other groups), and became increasingly important reef builders throughout the Mesozoic Era. They may have arisen from a rugose coral ancestor. Rugose corals built their skeletons of calcite and have a different symmetry from that of the scleractinian corals, whose skeletons are aragonite. However, there are some unusual examples of well-preserved aragonitic rugose corals in the Late Permian. In addition, calcite has been reported in the initial post-larval calcification in a few scleractinian corals. Nevertheless, scleractinian corals (which arose in the middle Triassic) may have arisen from a non-calcifying ancestor independent of the rugosan corals (which disappeared in the late Permian).

Output: 2