Context_1 : A female genital disease is a condition that affects the female reproductive system. Context_2 : Vaginal bleeding is any bleeding through the vagina, including bleeding from the vaginal wall itself, as well as (and more commonly) bleeding from another location of the female reproductive system, often the uterus. Generally, it is either a healthy physiologic response during the non-conceptional menstrual cycle or is caused by hormonal or other organic problems of the reproductive system, such as abnormal uterine bleeding. Vaginal bleeding may occur at any age, but always needs investigation when encountered in children or in postmenopausal women. Vaginal bleeding during pregnancy may indicate a possible pregnancy complication that needs to be medically addressed. Context_3 : The ovary (From , literally "egg" or "nut") is an ovum-producing reproductive organ, found in double pairs in the female as part of the vertebrate female reproductive system. Birds have only one functional ovary (the left), while the other remains vestigial. Ovaries in females are analogous to testes in males, in that they are both gonads and endocrine glands. Although ovaries occur in a wide variety of animals, both vertebrate and invertebrate, this article is primarily about human ovaries. Context_4 : Andrology (from Ancient Greek: ἀνήρ , "anēr", genitive ἀνδρός , "andros", "man"; and -λογία , "-logia") is the medical specialty that deals with male health, particularly relating to the problems of the male reproductive system and urological problems that are unique to men. It is also known as "the science of men". It is the counterpart to gynaecology, which deals with medical issues which are specific to the female reproductive system. However, unlike gynaecology, which has a plethora of medical board certification programs worldwide, andrology has none. Andrology has only been studied as a distinct specialty since the late 1960s: the first specialist journal on the subject was the German periodical "Andrologie" (now called "Andrologia"), published from 1969 onwards. Context_5 : Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. Context_6 : Estradiol (E2), also spelled oestradiol, is a steroid, an estrogen, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues such as the breasts, uterus, and vagina during puberty, adulthood, and pregnancy, but it also has important effects in many other tissues, including bone, fat, skin, liver, and the brain. While estrogen levels in men are lower compared to those in women, estrogens have essential functions in men, as well. It is found in most vertebrates and crustaceans, insects, fish, and other animal species. Context_7 : Gynaecology or gynecology (see spelling differences) is the medical practice dealing with the health of the female reproductive systems (vagina, uterus, and ovaries) and the breasts. Outside medicine, the term means "the science of women". Its counterpart is andrology, which deals with medical issues specific to the male reproductive system. Context_8 : The female reproductive system (or female genital system) is made up of the internal and external sex organs that function in human reproduction. The female reproductive system is immature at birth and develops to maturity at puberty to be able to produce gametes, and to carry a fetus to full term. The internal sex organs are the uterus and Fallopian tubes, and the ovaries. The uterus or womb accommodates the embryo which develops into the fetus. The uterus also produces vaginal and uterine secretions which help the transit of sperm to the Fallopian tubes. The ovaries produce the ova (egg cells). The external sex organs are also known as the "genitals" and these are the organs of the vulva including the labia, clitoris and vaginal opening. The vagina is connected to the uterus at the cervix. Context_9 : Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. "Estrogen" may also refer to any substance, natural or synthetic, that mimics the effects of the natural hormone. The estrane steroid estradiol is the most potent and prevalent endogenous estrogen, although several metabolites of estradiol also have estrogenic hormonal activity. Estrogens are used as medications as part of some oral contraceptives, in hormone replacement therapy for postmenopausal, hypogonadal, and transgender women, and in the treatment of certain hormone-sensitive cancers like prostate cancer and breast cancer. They are one of three types of sex hormones, the others being androgens/anabolic steroids like testosterone and progestogens like progesterone. Context_10 : Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland, and regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and luteinizing hormone (LH) work together in the reproductive system. fact_1 :  Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. fact_2 :  It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. "Estrogen" may also refer to any substance, natural or synthetic, that mimics the effects of the natural hormone. Question: Deslorelin acetate causes an initial surge of which hormone that develops and regulates female reproductive system?
Output: Estrogen