niryuu/sni-each-converted huggingface dataset:
On the fifth day after administration of a high dose of ARA-C (2 g/m2 intravenously every 12 hours), she developed bullous lesions on the hands and soles that disseminated, evolving to necrosis, sepsis, and death on the 22nd day.
Output: adverse drug event
Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHD.
Output: adverse drug event
We describe a case of advanced ovarian carcinoma who developed difficulty walking because of marked pain in the lower extremities and loss of proprioception 25 days after treatment with weekly taxol (80 mg/m(2)x3).
Output: adverse drug event
He became hyperkalemic on rechallenge with timolol and normokalemic following its withdrawal.
Output: adverse drug event
When thrombosis develops during heparin treatment, it is important to suspect HITTs and to assay for the associated antibodies, regardless of the actual platelet count.
Output: adverse drug event
A 31-year-old female developed multiple episodes of grand mal seizures after combination chemotherapy with cisplatin, vinblastine and bleomycin for germ cell ovarian cancer stage Ic.
Output: adverse drug event
Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil.
Output: adverse drug event
Pemphigus vulgaris precipitated by glibenclamide therapy.
Output: adverse drug event
Induction of systemic lupus erythematosus by interferon-gamma in a patient with rheumatoid arthritis.
Output: adverse drug event
CONCLUSIONS: Among the many presentations of ifosfamide neurotoxicity, clinicians should consider NCSE as a possible explanation for changes in consciousness in a patient receiving this agent.
Output: adverse drug event
CASE: We present an 11-year old male with Budd-Chiari syndrome who experienced profound worsening of chronic aphthous ulcers after immunosuppressive therapy was changed from tacrolimus to sirolimus.
Output: adverse drug event
We report a case of acute generalized exanthematous pustulosis (AGEP) in a 50-year-old woman that was attributed to the ingestion of nimesulide.
Output: adverse drug event
ARA-C is frequently associated with dermatologic toxicity, but this is only the second case of toxic epidermal necrolysis described in connection with this drug.
Output: adverse drug event
Acne provoked by gold seems not to have been described elsewhere.
Output: adverse drug event
Niflumic acid-induced skeletal fluorosis: iatrogenic disease or therapeutic perspective for osteoporosis?
Output: adverse drug event
PURPOSE: To determine the cause of spontaneous choroidal hemorrhage in a 67-year-old man after a myocardial infarction and administration of tissue plasminogen activator.
Output: adverse drug event
Cicatricial entropion associated with chronic dipivefrin application.
Output: adverse drug event
Treatment with infliximab is known to produce an increase of autoantibodies (antinuclear antibodies, anti-double-stranded DNA), but not clinical disease.
Output: adverse drug event
Two patients with extrinsic asthma and coexistent insulin-dependent diabetes mellitus sustained an anaphylactoid reaction after the intravenous administration of 50% solution of dextrose.
Output: adverse drug event
Physicians should therefore be aware of its occurrence and carefully monitor serum levels of CPK, GOT and GPT during the treatment of diabetes insipidus with clofibrate, especially in patients with associated hypothyroidism, latent or overt, which possibly favors the development of myopathy.
Output: adverse drug event
After receiving 3 doses of ifosfamide/mesna, she was found to be unresponsive.
Output: adverse drug event
Methotrexate-associated nephropathy is a rare complication in pediatric oncology, and a review of the literature suggests that exposure to nephrotoxic agents may be a significant but perhaps underrecognized risk factor for its development.
Output: adverse drug event
It has been reported that fluoroquinolone antimicrobials prolong the corrected QT interval but rarely cause torsade de pointes.
Output: adverse drug event
Despite a postulated dopaminergic mechanism, there seems to have been only one previous report of amantadine's precipitating psychosis in a schizophrenic patient.
Output: adverse drug event
This is the first report of a catatonic syndrome occurring in a patient receiving disulfiram treatment.
Output: adverse drug event
In summary, we report herein the first case of SIADH believed to be an adverse effect of mizoribin, which may therefore needed to be added to the list of drugs which can induce SIADH.
Output: adverse drug event
Generalised cutaneous rash associated with ganciclovir therapy has rarely been reported in literature.
Output: adverse drug event
A 71-year-old man, who had a history of a previous bullous drug reaction to a sulfonamide, began receiving an ophthalmic preparation that contained sulfacetamide sodium.
Output: adverse drug event
Paroxysmal supraventricular tachycardia during treatment with cisplatin and etoposide combination.
Output: adverse drug event
A 57-year-old woman with right bundle branch block +LPH and ventricular premature contractions developed complete heart block (CHB) following administration of disopyramide phosphate (Norpace).
Output: adverse drug event
Rifampin (RFP) increases hepatic microsomal enzyme activity, and there are case reports of RFP-induced hypothyroidism, all associated with Hashimoto's thyroiditis.
Output: adverse drug event
Heparin-induced hyperkalemia.
Output: adverse drug event
Interferon-induced psychosis as a "psychiatric contraindication" to hepatitis C treatment: a review and case-based discussion.
Output: adverse drug event
OBJECTIVE: The authors described a case of interferon-induced psychosis as a framework to review the literature and discuss the decision to pursue antiviral treatment in psychiatrically ill patients with hepatitis C.
Output: adverse drug event
Cutaneous vasculitis secondary to ramipril.
Output: adverse drug event
Case 2, a 29-year-old woman, developed bilateral optic neuritis combined with numbness of the lower extremities as well as bowel and bladder dysfunction after a 22-month use of recombinant interferon alpha-2b for chronic myelogenous leukemia.
Output: adverse drug event
Soon after introduction of insulin therapy, she developed severe anasarca, including marked peripheral oedema, ascites and pleural effusion.
Output: adverse drug event
We present a pediatric patient with leukemia and a severe, L-asparaginase-induced necrotizing pancreatitis, treated successfully with percutaneous drainage used to flush the infected necrotic parts.
Output: adverse drug event
Recently, some studies have also reported association between patients with juvenile rheumatoid arthritis (JRA) treated with Methotrexate (MTX) and malignant lymphoma developing.
Output: adverse drug event
Gabapentin-induced mood changes with hypomanic features in adults.
Output: adverse drug event
The pulmonary toxicity is probably induced by piritrexim.
Output: adverse drug event
Antacid and sucralfate-induced hypophosphatemic osteomalacia: a case report and review of the literature.
Output: adverse drug event
RESULTS: Evidence of neurological improvement and rehabilitation potential after severe myelopathy due to intrathecal injection of doxorubicin.
Output: adverse drug event
CONCLUSIONS: Cicatrization in the substantia propria of the conjunctiva by excessive lymphocytic infiltration after topically administered antiglaucoma drugs including dipivefrin is a possible mechanism of action for entropion.
Output: adverse drug event
Severe adenovirus pneumonia (AVP) following infliximab infusion for the treatment of Crohn's disease.
Output: adverse drug event
We report the syndrome of inappropriate antidiuresis as a much earlier side-effect of carbamazepine administration in a 29-year Nigerian female patient with generalized tonic-elonic seizures.
Output: adverse drug event
We report a cae of paranoid psychosis following use of a decongestant containing PPA and summarize the case report literature of psychiatric adverse effects to PPA in which doses were known and stated to be within recommended guidelines.
Output: adverse drug event
Dapsone-induced erythroderma with Beau's lines.
Output: adverse drug event
A 72-year-old woman with a history of thyrotoxicosis presented with sore throat and fever two weeks after starting carbimazole.
Output: adverse drug event
Nail-changes induced by penicillamine.
Output: adverse drug event
Verapamil is widely used for the termination of paroxysmal supraventricular tachycardia (PSVT) with little proarrhythmic effect.
Output: adverse drug event
The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient: growth deficiency, developmental delay, craniosynostosis, blepharophimosis, flat nasal bridge, abnormal ears, and distal limb defects including hypoplastic thumbs and oligodactyly.
Output: adverse drug event
CONCLUSION: A 37-year-old African- American man with G6PD deficiency developed hemolytic anemia, hepatitis, orthostatic hypotension, and aseptic meningitis simultaneously after using trimethoprim-sulfamethoxazole.
Output: adverse drug event
Findings on discontinuation and rechallenge supported the assumption that the hair loss was a side effect of the paroxetine.
Output: adverse drug event
Since the thrombocyte count started to increase immediately after initiation and dropped immediately after discontinuation of ciprofloxacin and tazobactam/piperacillin and all other drugs were discontinued already before or were started after the nadir of the thrombocyte count, these two antibiotics were regarded causative.
Output: adverse drug event
The nephrotic syndrome developed in a patient receiving therapy with gold for rheumatoid arthritis.
Output: adverse drug event
Four cases of adverse experiences with clonidine are described.
Output: adverse drug event
CONCLUSION: The new quinolone derivatives (levofloxacin, sparfloxacin, grepafloxacin, trovafloxacin, gatifloxacin and moxifloxacin), also called gyrase inhibitors, are known for their potential to cause central nervous system-related adverse effects, including headache, dizziness and insomnia.
Output: adverse drug event
Nail staining from hydroquinone cream.
Output: adverse drug event
5-fluorouracil (5-FU)-associated peripheral neuropathy is an uncommon event.
Output: adverse drug event
Two cases of sirolimus-associated pneumonitis have been reported after cardiac transplantation.
Output: adverse drug event
The patient experienced muscle twitches, tremulousness, and anxiety on day 17 of foscarnet therapy.
Output: adverse drug event
The oligohidrosis caused by zonisamide was reversible in that the patient regained the ability to sweat within 2 weeks of the cessation of drug administration.
Output: adverse drug event
Concomitant administration of lithium with olanzapine may place patients at risk for NMS.
Output: adverse drug event
Gold nephropathy due to auranofin obscured by tolmetin pseudoproteinuria.
Output: adverse drug event
A 27-year-old man who had a history of bronchial asthma, eosinophilic enteritis, and eosinophilic pneumonia presented with fever, skin eruptions, cervical lymphadenopathy, hepatosplenomegaly, atypical lymphocytosis, and eosinophilia two weeks after receiving trimethoprim (TMP)-sulfamethoxazole (SMX) treatment.
Output: adverse drug event
Flucytosine-associated diarrhea has been previously described in 6%-10% of patients receiving the drug.
Output: adverse drug event
The increasing prevalence of methamphetamine abuse and the severity of the associated ulcers should alert ophthalmologists to the problem of methamphetamine-related keratitis.
Output: adverse drug event
We evaluated a patient who developed a psychotic disorder after 4 months of isoniazid prophylaxis for a positive tuberculosis tine test.
Output: adverse drug event
We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.
Output: adverse drug event
The authors postulate that two types of combined lithium-neuroleptic toxicity occur: a neuroleptic malignant extrapyramidal syndrome and a lithium toxicity that occurs in combination with phenothiazines, primarily thioridazine.
Output: adverse drug event
The events of non-convulsive status epilepticus subsided following reduction in tiagabine dosages.
Output: adverse drug event
RESULTS: After 4- to 14-month period of therapy with the combination of indapamide (2.5 mg/day) and fosinopril (10 mg/day) in three patients and 6-month period of monotherapy with indapamide (2.5 mg/day) in one patient, glucose levels of all patients increased and achieve criteria of diabetes diagnoses.
Output: adverse drug event
Anastrozole-associated sclerosing glomerulonephritis in a patient with breast cancer.
Output: adverse drug event
We report the first case of fulminant adult respiratory distress syndrome (ARDS) associated with pegylated interferon alpha-2a (pegIFNalpha-2a) and ribavirin use for hepatitis C, complicated by subsequent and ultimately fatal sepsis and multiorgan failure.
Output: adverse drug event
A reversible toxic liver damage was observed in a non-alcoholic woman treated with disulfiram.
Output: adverse drug event
The administration of "sweet spirits of nitre" (4% ethyl nitrite CH3CH2ONO in 70% ethyl alcohol) was followed by acute methemoglobinemia and severe anoxic metabolic acidosis in infant twins, Methylene blue administration reversed methemoglobinemia in both, but one twin died from the consequences of hypoxemia.
Output: adverse drug event
Delusional parasitosis associated with phenelzine.
Output: adverse drug event
The reported case represents an unusual association between medication with the proton pump inhibitor lansoprazole and the development of collagenous colitis suggesting the importance of evaluation of drug use in patients with microscopic colitis.
Output: adverse drug event
CASE SUMMARY: A 45-year-old HIV-positive man (CD4+ count 450 cells/mm(3) and history of AIDS-defining illness) presented with JHR after an initial intravenous dose of penicillin G for presumed neurosyphilis.
Output: adverse drug event
A fatal massive pulmonary embolus developed in a patient treated with streptokinase for acute deep vein thrombosis.
Output: adverse drug event
Tamoxifen is suggested to be carcinogenic both through direct genotoxic and epigenetic mechanisms.
Output: adverse drug event
Bull's-eye maculopathy associated with quinacrine therapy for malaria.
Output: adverse drug event
PURPOSE: We studied a case of vortex keratopathy that was associated with the use of atovaquone.
Output: adverse drug event
This report describes a probable case of infliximab-induced membranous nephropathy.
Output: adverse drug event
Massive prolapse of the urethral mucosa following periurethral injection of calcium hydroxylapatite for stress urinary incontinence.
Output: adverse drug event
Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures.
Output: adverse drug event
Interference with the cortisol axis by the microtubule antagonist, CPH82.
Output: adverse drug event
Carbamazepine hypersensitivity syndrome is a rare, life-threatening condition.
Output: adverse drug event
We report a case of an 11-year-old boy who experienced an anaphylactic reaction after administration of bacitracin ointment.
Output: adverse drug event
Multicentric hepatocellular carcinoma following phosphate diethylstilbestrol therapy for prostatic cancer.
Output: adverse drug event
In one case, disulfiram was the only potential teratogen exposed to the fetus.
Output: adverse drug event
We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII.
Output: adverse drug event
We describe 2 patients with cutaneous lupus erythematosus who developed severe dapsone reaction after low dose therapy, with a fatal outcome in one.
Output: adverse drug event
Amphotericin B overdose in pediatric patients with associated cardiac arrest.
Output: adverse drug event
Two patients with osteomyelitis who developed reversible cholestatic jaundice during treatment with oxacillin derivatives are described.
Output: adverse drug event
Here, we describe a case of Vogt-Koyanagi-Harada disease occurring 4 months after the start of interferon alpha treatment, probably induced by the immunomodulatory effects of interferon.
Output: adverse drug event
Isoniazid inhibits the conversion of tryptophan to niacin and may induce pellagra, particularly in poorly nourished patients.
Output: adverse drug event
Moreover, treatment with immunosuppressive drugs such as cyclosporine, cisplatin, tacrolimus, and interferon-alpha can induce a condition resembling RPLS.
Output: adverse drug event
CASE: We report a case of a woman with severe human insulin-induced lipoatrophy who has been treated exclusively with recombinant DNA human insulin since the onset of IDDM.
Output: adverse drug event
We report a case admitted with a first-detected, symptomatic paroxysmal atrial fibrillation in a healthy patient after self-medication with vardenafil.
Output: adverse drug event
By means of the in vitro heparin-induced platelet activation (HIPA) assay it was shown that standard heparin and the LMW heparins Fragmin and Fraxiparin (Sanofi Labaz, Munich, FRG), as well as the enoxaparine Clexane (Nattermann, Cologne, FRG), all induced platelet activation with the patient's serum.
Output: adverse drug event
CASE REPORT: A six-year-old boy with transfusion-dependent beta-thalassaemia developed a unilateral hearing loss shortly after commencing desferrioxamine therapy.
Output: adverse drug event
Physicians should be aware of the potential for developing a gemcitabine-induced radiation recall reaction resulting in hemodynamically significant pericardial effusion.
Output: adverse drug event
An apparent link is described between the use of MMF with prednisone to treat pemphigus vulgaris and the development of red blood cell anemia.
Output: adverse drug event
IFNalpha-induced recurrence of Graves' disease ten years after thyroidectomy in chronic viral hepatitis C.
Output: adverse drug event
BACKGROUND: Aphthous stomatitis, a common mucocutaneous disorder, is a well accepted complication of sirolimus therapy.
Output: adverse drug event
CONCLUSION: Healthcare professionals should be aware of the possible development of serotonin syndrome as a complication of initiation of fentanyl and other phenylpiperidine opioids in patients treated with SSRIs.
Output: adverse drug event
Symptoms and signs of augmentation were related to low plasma levodopa levels, abating 75 minutes after oral levodopa administration and reappearing after 3 hours, closely mirroring the rapid rise and fall of plasma levodopa concentration.
Output: adverse drug event
Amiodarone-induced dysthyroidism.
Output: adverse drug event
This case had radiation fibrosis, so we suggest that radiation fibrosis may be another contributor of the occurrence of ILD in patients taking erlotinib.
Output: adverse drug event
Symptomatic hypocalcaemia and renal impairment associated with bisphosphonate treatment in patients with multiple myeloma.
Output: adverse drug event
A 22-year-old black man developed fever, chills, fatigue, night sweats, tender lymphadenopathy, and a generalized, pruritic, macular eruption 3 weeks after starting minocycline therapy for acne.
Output: adverse drug event
Abdominal wall ulceration and mucinosis secondary to recombinant human interferon-beta-1b.
Output: adverse drug event
We describe a case of poisoning with 3,4-methylenedioxymet-amphetamine Ecstasy that presented with all the features suggestive of a fatal outcome, including a creatinine phosphokinase level markedly higher than any previously reported.
Output: adverse drug event
We describe a case of an NHL patient who received rituximab and developed symptomatic, biopsy-proven multinodular bronchiolitis obliterans with organizing pneumonia (BOOP).
Output: adverse drug event
A patient with an allergy to a macrolide antibiotic was given tacrolimus and developed a sudden cutaneous reaction.
Output: adverse drug event
Gemcitabine-related radiation recall in a patient with pancreatic cancer.
Output: adverse drug event
This eruption emerged after 1 month of therapy with salsalate, persisted for as long as salsalate was administered, and cleared within 3 weeks of discontinuing the medication.
Output: adverse drug event
Amikacin-induced type 5 Bartter-like syndrome with severe hypocalcemia.
Output: adverse drug event
A new type of minocycline-induced cutaneous hyperpigmentation.
Output: adverse drug event
We report a case of acute generalized exanthematous pustulosis (AGEP) induced by salazosulfapyridine in a patient with ulcerative colitis.
Output: adverse drug event
Six patients with no previous signs or symptoms suggestive of coronary artery disease developed acute coronary ischemia/infarction shortly after cis-diamine-dichloroplatinum II (cisplatin) -based chemotherapy.
Output: adverse drug event
We describe 3 AS patients treated with etanercept for active AS who developed new onset of CD while AS related symptoms responded well to etanercept.
Output: adverse drug event
To our knowledge, this is the first case of spontaneous remission of MTX-associated gastric LPD after discontinuation of MTX therapy.
Output: adverse drug event
Zidovudine use in pregnancy: a report on 104 cases and the occurrence of birth defects.
Output: adverse drug event
The patient was diagnosed with carbamazepine toxicity related to the introduction of ritonavir.
Output: adverse drug event
Although fluoxetine-induced headache occurred in one patient, the other five reported no side effects at the doses used.
Output: adverse drug event
Pulmonary hypertension during lithium therapy: clinical case study.
Output: adverse drug event
In this report, we describe a patient receiving lenalidomide in whom dyspnea, fever, hypoxia, and diffuse pulmonary infiltrates developed.
Output: adverse drug event
Inappropriate antidiuretic hormone following adenine arabinoside administration.
Output: adverse drug event
Lithium therapy was discontinued because of poor compliance to the medication and intolerable polyuria.
Output: adverse drug event
We describe the exceptional development of AML and lung cancer in a patient with previously diagnosed CLL in minimal residual disease status after fludarabine treatment followed by autologous peripheral blood stem-cell transplantation.
Output: adverse drug event
Interstitial fibrosis of the lung is a potential complication of methotrexate therapy for psoriasis.
Output: adverse drug event
Secondary hyperparathyroidism in certain patients with lithium nephrotoxicity is also possible.
Output: adverse drug event
The authors presented a case of pulmonary hypertension during lithium therapy, while she has been on lithium for 6 years.
Output: adverse drug event
Development of Crohn's disease in a patient with multiple sclerosis treated with copaxone.
Output: adverse drug event
Methamphetamine's extensive physiologic effects, inconsistent street purity, and multiple routes of administration offer many possibilities for injury to the cornea.
Output: adverse drug event
Neuroleptic malignant syndrome in an adolescent receiving olanzapine-lithium combination therapy.
Output: adverse drug event
A case of acute cardiomyopathy and pericarditis associated with methylphenidate.
Output: adverse drug event
Autopsy findings were consistent with bleomycin and oxygen-induced pulmonary damage.
Output: adverse drug event
PURPOSE: Symptomatic visual field constriction thought to be associated with vigabatrin has been reported.
Output: adverse drug event
Carbamazepine-induced systemic lupus erythematosus-like disease.
Output: adverse drug event
We report a case of biopsy-proven acute tubulointerstitial nephritis associated with a second course of flurbiprofen, a nonsteroidal anti-inflammatory drug of the propionic acid class.
Output: adverse drug event
BACKGROUND: Headaches have been reported as a potential side effect of capecitabine therapy.
Output: adverse drug event
Pseudomembranous colitis readily occurs in at least certain population groups receiving trimethoprim-sulfamethoxazole.
Output: adverse drug event
Pravastatin is associated with myotonia in animals.
Output: adverse drug event
Infliximab and its serious adverse effects are discussed, and other cases of osteomyelitis with infliximab use are also reviewed.
Output: adverse drug event
The incidence of angioedema secondary to losartan, an angiotensin II receptor antagonist, is unknown.
Output: adverse drug event
Dipyrone-induced granulocytopenia: a case for awareness.
Output: adverse drug event
Pneumocystis pneumonia should be considered in asthmatic patients taking methotrexate who present with fever, pulmonary infiltrates, and hypoxia.
Output: adverse drug event
Despite these antithrombotic effects, the patient developed repeated venous thromboembolism during treatment with low-molecular-weight heparin.
Output: adverse drug event
The elicitation of a movement disorder by trazodone: case report.
Output: adverse drug event
We report the case of a 20-year-old woman originally from Cameroon who was infected by the L. loa parasite and developed severe hepatitis, identified 1 month after a single dose of ivermectin.
Output: adverse drug event
However, we have recently had four cases of clofibrate-induced myopathy in patients with diabetes insipidus due to hypothalamic lesions.
Output: adverse drug event
Toxic hepatitis due to combination therapy with methotrexate and etretinate in psoriasis.
Output: adverse drug event
We describe a case of interstitial hypoxaemiant pneumonitis probably related to flecainide in a patient with the LEOPARD syndrome, a rare congenital disorder.
Output: adverse drug event
The patient's other comorbidities and medications have not been suggested as possible interactions with sertraline that can cause rhabdomyolysis.
Output: adverse drug event
However, several case reports have suggested that clozapine could also cause TD.
Output: adverse drug event
Therefore, although garenoxacin reportedly causes fewer adverse reactions for cardiac rhythms than third-generation quinolone antibiotics, one must be cautious of the interference of other drugs during hypokalemia in order to prevent TdP.
Output: adverse drug event
Severe dapsone hypersensitivity syndrome.
Output: adverse drug event
Sorafenib induced tumor lysis syndrome in an advanced hepatocellular carcinoma patient.
Output: adverse drug event
The authors suggest that in the absence of any proven benefit of itraconazole prophylaxis, and given the interaction of this drug with vincristine leading to severe and even potentially fatal toxicities, the combination use of these drugs should be avoided.
Output: adverse drug event
We report four patients, three of whom first developed psoriasis and one who had an aggravation of the condition during treatment with interferon-alpha.
Output: adverse drug event
Escape atrial complexes, which occurred following junctional premature complexes, failed to initiate tachycardia in the control state but tachycardia was always reinitiated by an identical escape sequence after procainamide.
Output: adverse drug event
Prominent eye movements during NREM sleep and REM sleep behavior disorder associated with fluoxetine treatment of depression and obsessive-compulsive disorder.
Output: adverse drug event
We describe 2 male patients, a 49-year-old with psoriatic arthritis and impaired renal function and a 43-year-old renal transplant recipient, who both sustained a marked decline in glomerular filtration rate in conjunction with a selective inhibitor of cyclooxygenase-2 (COX-2), rofecoxib.
Output: adverse drug event
Paralytic ileus in patients undergoing bortezomib treatment has been reported, although a definite attribution to bortezomib administration has not been established.
Output: adverse drug event
A 52-year-old Black woman on phenytoin therapy for post-traumatic epilepsy developed transient hemiparesis contralateral to the injury.
Output: adverse drug event
A 45-year-old woman with steroid-dependent Crohn's colitis, successfully managed with maintenance infliximab infusions and methotrexate, developed a lupus-like syndrome eight months after her initial infusion.
Output: adverse drug event
Metronidazole neuropathy.
Output: adverse drug event
Case 3: A 29-year-old female alcoholic complained of general fatigue and a slight fever after 1.5 years of abstinence with cyanamide treatment.
Output: adverse drug event
A woman developed delusional parasitosis when taking phenelzine.
Output: adverse drug event
Tacrolimus (FK506), an immunosuppressant, has been associated with mutism in adults after liver transplant.
Output: adverse drug event
This is the first reported case of suspected DIAN due to cefuroxime.
Output: adverse drug event
Pellagra encephalopathy among tuberculous patients: its relation to isoniazid therapy.
Output: adverse drug event
The association of central diabetes insipidus (CDI) with lithium use is rare.
Output: adverse drug event
Intravenous sodium bicarbonate appears to be indicated prophylactically in combating the associated metabolic acidosis due to absorbed formic acid.
Output: adverse drug event
This case and a review of the literature show the severe and unpredictable nature of ethambutol toxicity and its potential for irreversible vision loss despite careful ophthalmologic monitoring.
Output: adverse drug event
In all three cases, autopsy revealed gross and microscopic features indistinguishable from those seen in the Hamman-Rich syndrome, and methotrexate hepatotoxicity was present in one.
Output: adverse drug event
Massive CBZ OD may produce a reversible encephalopathy that includes cortical hyperexcitability, a profound burst-suppression EEG pattern, and cranial nerve areflexia.
Output: adverse drug event
Two patients are described who developed sensory neuropathy after the ingestion of 30.6 and 114 g metronidazole respectively.
Output: adverse drug event
We report a case of fulminant neuroleptic malignant syndrome in a man aged 70 developing within 12 hours of starting six-hourly intravenous metoclopramide.
Output: adverse drug event
Surprisingly, we found that three patients appeared to develop tardive OGC while taking clozapine.
Output: adverse drug event
We report a case of Zidovudine induced anaemia and bone marrow aplasia in a patient infected with HIV.
Output: adverse drug event
Valproic acid induced coma is presented in an adult patient without a history of metabolic disease.
Output: adverse drug event
Prick tests and intradermal tests with a series of dilutions of carboplatin and cisplatin were performed on three patients who had exhibited medium and severe hypersensitivity reactions to carboplatin.
Output: adverse drug event
This is a report of a renal transplant patient with Pneumocystis pneumonia who developed chemical cellulitis and ulceration following the extravasation of intravenous pentamidine into the soft tissues of the left hand and forearm.
Output: adverse drug event
Mycophenolate mofetil-induced neutropenia in liver transplantation.
Output: adverse drug event
Acute hyperphosphatemia caused by sodium phosphate enema in a patient with liver dysfunction and chronic renal failure.
Output: adverse drug event
Central nervous system manifestations of an ibuprofen overdose reversed by naloxone.
Output: adverse drug event
A 22-year-old drug-abuser injected flunitrazepam tablets dissolved in tap water into her left femoral artery and presented with clinical signs of acute ischaemia of the left leg.
Output: adverse drug event
Ulcer became worse after tobramycin and gentamycin treatment for 2 days.
Output: adverse drug event
Linear IgA bullous dermatosis occurring after carbamazepine.
Output: adverse drug event
This is an image and brief case report of a 13-year-old boy who presented with severe rash and systemic symptoms after starting oxcarbazepine.
Output: adverse drug event
Type II heparin-induced thrombocytopenia (HIT) is an immunological disorder characterized by antibodies to heparin-platelet factor 4 complexes and a high risk of thrombotic complications.
Output: adverse drug event
We present a case of HUS in an advanced ovarian cancer patient treated with carboplatin and gemcitabine, and described its favorable outcome after chemotherapy interruption and supportive care with a 1 year follow-up.
Output: adverse drug event
Triazolam-induced nocturnal bingeing with amnesia.
Output: adverse drug event
The international literature regarding opportunistic infections after immunosuppressive therapy with alemtuzumab with particular attention on fungal infections has also been reviewed.
Output: adverse drug event
CONCLUSIONS: Amphotericin B overdose can be fatal in children and infants.
Output: adverse drug event
CONCLUSIONS: Amphotericin B seems to be the probable cause of the seizures.
Output: adverse drug event
Propylthiouracil-induced sensorineural hearing loss associated with antineutrophil cytoplasmic antibodies.
Output: adverse drug event
We report a case of Thrombotic Thrombocytopenic Purpura occurring as an allergic response to trimethoprim-sulfamethoxazole therapy (Bactrim, Septra) in a Jehovah's Witness patient.
Output: adverse drug event
Vanishing bile duct and Stevens-Johnson syndrome associated with ciprofloxacin treated with tacrolimus.
Output: adverse drug event
Amphotericin B nephrotoxicity in humans decreased by salt repletion.
Output: adverse drug event
Cephalexin rash in infectious mononucleosis.
Output: adverse drug event
This is a rare case of ARDS associated with lithium intoxication.
Output: adverse drug event
A 77-year-old man developed ankle, hand, and facial swelling 2 weeks after starting rosiglitazone.
Output: adverse drug event
We postulate that gastritis caused by dexamethasone, mucositis caused by doxorubicin, and the unique anatomic nature of a Meckel diverticulum may have contributed to this extremely unlikely and previously unreported event.
Output: adverse drug event
Muscle biopsy revealed variation in muscle fiber size and few vacuolated fibers which were features of colchicine-induced myopathy.
Output: adverse drug event
We report a case of generalized cutaneous sclerosis associated with muscle and oesophageal involvement in a patient exposed to herbicides containing bromocil, diuron and aminotriazole.
Output: adverse drug event
Acute interstitial nephritis due to pantoprazole.
Output: adverse drug event
We report the case of a female acromegalic patient in whom multiple hepatic adenomas appeared soon after danazol treatment for uterine fibromatosis.
Output: adverse drug event
We describe a 5-year-old girl showed recovery of vincristine induced cranial polyneuropathy with pyridoxine and pyridostigmine treatment.
Output: adverse drug event
We report on a patient with renal artery stenosis who had only 1 kidney and in whom acute renal impairment developed with transient anuria after the administration of captopril.
Output: adverse drug event
We present a 46-year-old African-American man with AIDS who was admitted on two different occasions within three weeks for signs and symptoms of meningitis after using trimethoprim/sulfamethoxazole (TMP/SMX).
Output: adverse drug event
Increased libido in a woman treated with fluvoxamine: a case report.
Output: adverse drug event
Physicians using this "new" drug must be aware of the potential danger of sulfonamide-induced injury to the urinary tract.
Output: adverse drug event
Cefoxitin therapy for Mycobacterium fortuitum bacteremia with associated granulomatous hepatitis.
Output: adverse drug event
Zolpidem tissue concentrations in a multiple drug related death involving Ambien.
Output: adverse drug event
Osteomyelitis occurring during infliximab treatment of severe psoriasis.
Output: adverse drug event
Sulfadiazine crystalluria revisited.
Output: adverse drug event
Amiodarone is well recognized as an anti-arrhythmic drug containing a high dose of iodine with considerable potential to cause thyroid dysfunction.
Output: adverse drug event
BACKGROUND: Reproductive endocrine disorders characterized by menstrual disorders, polycystic ovaries, and hyperandrogenism seem to be common among women treated with sodium valproate for epilepsy.
Output: adverse drug event
Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease.
Output: adverse drug event
Anaphylactoid reaction to methylprednisolone pulsed therapy for multiple sclerosis.
Output: adverse drug event
Scrotal ulceration induced by all-trans retinoic acid in a patient with acute promyelocytic leukemia.
Output: adverse drug event
Possible interaction between lopinavir/ritonavir and valproic Acid exacerbates bipolar disorder.
Output: adverse drug event
It is very likely that the dexamethasone used in the antiemetic drug regimen contributed to the development of osteonecrosis in these patients.
Output: adverse drug event
Dilated cardiomyopathy associated with chronic overuse of an adrenaline inhaler.
Output: adverse drug event
Response of a promethazine-induced coma to flumazenil.
Output: adverse drug event
Prolonged responses were achieved with low doses of HU (3-10 mg/kg/day) and higher doses were associated with mild reversible hematologic or hepatic toxicity and no further increases in Hb.
Output: adverse drug event
Thalidomide neuropathy in childhood.
Output: adverse drug event
We report 4 patients, 2 on methylphenidate and 2 on dextroamphetamine who presented with acral cyanosis, livedo reticularis, or Raynaud phenomenon.
Output: adverse drug event
Capecitabine was discontinued and the allergic reactions resolved after the woman took diphenhydramine for 1 week.
Output: adverse drug event
We report a case of fatal pulmonary toxicity in a patient with advanced non-small cell lung cancer who received erlotinib.
Output: adverse drug event
Heparin-associated thrombocytopenia: successful therapy with the heparinoid Org 10172 in a patient showing cross-reaction to LMW heparins.
Output: adverse drug event
Though physicians treating large populations of patients with HIV are well aware of this complication, only one other report of nevirapine-associated SJS has been documented in the dermatology literature.
Output: adverse drug event
Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia.
Output: adverse drug event
We believe that this is the first description of acute hepatitis caused by an idiosyncratic adverse reaction to gliclazide or to one of its metabolites.
Output: adverse drug event
Transient leucopenia and thrombocytopenia associated with sodium nitroprusside infusion.
Output: adverse drug event
Our patient developed both nephrogenic diabetes insipidus and renal tubular acidosis with a temporal pattern that demonstrated a link between foscarnet therapy and these abnormalities.
Output: adverse drug event
A case of tuberculosis in a patient on Efalizumab and Etanercept for treatment of refractory palmopustular psoriasis and psoriatic arthritis.
Output: adverse drug event
Penicillin-induced Jarisch-Herxheimer reaction.
Output: adverse drug event
Under the suspicion of amiodarone-induced acute pancreatitis, amiodarone was substituted by propafenone.
Output: adverse drug event
Although vasculitis has been reported in the course of hairy cell leukaemia, it has only rarely been reported as the consequence of cladribine treatment.
Output: adverse drug event
Imidazoline intoxication in children.
Output: adverse drug event
Reversible heart failure in a patient receiving etanercept for ankylosing spondylitis.
Output: adverse drug event
METHODS: A retrospective report of the first case of gemcitabine-related HUS, in a patient with metastatic pancreatic adenocarcinoma, treated with a variety of standard therapies in addition to rituximab is presented.
Output: adverse drug event
Severe acute encephalopathy following inadvertent intrathecal doxorubicin administration.
Output: adverse drug event
There is no consensus on the treatment of ticlopidine-induced marrow aplasia.
Output: adverse drug event
We have successfully overcome severe neutropenia in an RA patient treated with gold salts, using granulocyte colony-stimulating factor (G-CSF), reducing the duration of neutropenia and risk of infection.
Output: adverse drug event
Dexamethasone treatment of amiodarone-induced thyrotoxicosis (AIT) with or without persistent administration of the drug.
Output: adverse drug event
Acute acoustic nerve palsy associated with vincristine therapy.
Output: adverse drug event
In this case report, we have described a patient with Crohn's disease who developed subfulminant hepatitis B after the fourth infusion of infliximab due to an unrecognized HBs-antigen carrier state.
Output: adverse drug event
The concomitant use, however, of colchicine and statin has been associated with the rapid onset of muscle weakness.
Output: adverse drug event
Quetiapine-induced leucopenia and thrombocytopenia.
Output: adverse drug event
When the trazodone was reduced, the involuntary movements promptly ceased.
Output: adverse drug event
The potential for progressive brain injury and subsequent disability related to intraventricular IL-2 therapy is discussed.
Output: adverse drug event
Nifedipine may induce, or aggravate, pre-existing, gastro-oesophageal reflux.
Output: adverse drug event
After extensive neurological 'work up', we realized that the anisocoria was related to the transdermal scopolamine patch that we had prescribed for weaning off the opioid.
Output: adverse drug event
Conversely, diffuse interstitial pulmonary fibrosis should be considered in the differential diagnosis of patients receiving methotrexate who develop bilateral pulmonary infiltrates seen on chest roentgenograms.
Output: adverse drug event
We report a case of successful surgical management of arterial thrombosis after percutaneous thrombin injection of a femoral artery pseudoaneurysm in a 69-year-old woman.
Output: adverse drug event
As these cases revealed, close monitoring of blood chemistry is mandatory after starting spironolactone, and patients should be advised to stop spironolactone immediately if diarrhoea develops.
Output: adverse drug event
However, a large case-control study included three cases of either Stevens-Johnson syndrome or toxic epidermal necrolysis associated with ofloxacin use, but no details of the cases were given.
Output: adverse drug event
However, follow-up revealed that gestational diabetes when associated with norethisterone had a lesser risk of emerging diabetes mellitus and impaired glucose tolerance.
Output: adverse drug event
Nine delirious patients suffering from lithium intoxication were examined with the Mini-Mental State Exam (MMS) to describe the clinical course of the disorder.
Output: adverse drug event
After abstinence from oolong tea his delirium resolved.
Output: adverse drug event
The development of systemic lupus erythematosus (SLE) after 38 months of therapy with recombinant human interferon gamma (rIFN-gamma) was observed in a patient with rheumatoid arthritis.
Output: adverse drug event
Diclofenac-associated hepatitis.
Output: adverse drug event
The use of rituximab has been uncommonly associated with delayed pulmonary toxicity.
Output: adverse drug event
Although the t-AML developed following oral etoposide therapy, the child had previously received high-dose, multiagent chemotherapy, and rearrangement of the MLL gene was not demonstrated.
Output: adverse drug event
We report a case of exfoliative dermatitis clearly linked to intravenous and intraperitoneal administration of tobramycin.
Output: adverse drug event
No cases of renal acidosis, and only one case of nephrogenic diabetes insipidus, has been previously reported as a complication of foscarnet treatment.
Output: adverse drug event
Successful treatment with carbimazole of a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration: a case report.
Output: adverse drug event
After five and six weeks of continuous oral administration of methylprednisolone, the boys developed steroid diabetes.
Output: adverse drug event
We describe a 15-year-old female patient diagnosed with acute lymphoblastic leukemia presenting with status epilepticus after receiving intrathecal methotrexate.
Output: adverse drug event
We report an additional case of isotretinoin teratogenicity in which the patient had agenesis of the cerebellar vermis, multiple leptomeningeal neuroglial heterotopias, hydrocephalus, and abnormalities of the corticospinal tracts.
Output: adverse drug event
Clonidine-induced bradycardia in patients with spinal cord injury.
Output: adverse drug event
Spontaneous nasal septal perforation with antiangiogenic bevacizumab therapy.
Output: adverse drug event
A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented.
Output: adverse drug event
Withdrawal of Depakote resulted in resolution of the effusion.
Output: adverse drug event
A 54-year-old man, treated with amiodarone, developed thyrotoxicosis.
Output: adverse drug event
Delayed neurotoxicity of intraventricular interleukin-2: a case report.
Output: adverse drug event
Extensive forearm deep venous thrombosis following a severe infliximab infusion reaction.
Output: adverse drug event
CASE SUMMARY: A 57-year-old female with cardiomyopathy and "sulfa" (trimethoprim/sulfamethoxazole) allergy documented as pancreatitis presented with symptoms consistent with pancreatitis after use of furosemide.
Output: adverse drug event
Increased awareness is needed on the possible occurrence of LPD resembling gastric cancer in rheumatoid arthritis patients treated with MTX.
Output: adverse drug event
Severe hyperkalemia occurred in a patient with radiation pneumonitis and glaucoma shortly after beginning prednisone therapy.
Output: adverse drug event
Choroidal hemorrhage associated with systemic tissue plasminogen activator.
Output: adverse drug event
Gold nephropathy.
Output: adverse drug event
Statin-associated myasthenia gravis: report of 4 cases and review of the literature.
Output: adverse drug event
Propranolol: an unrecognized cause of central nervous system dysfunction in patients undergoing cardiopulmonary bypass.
Output: adverse drug event
This case extends the spectrum of fludarabine pulmonary toxicity to include pulmonary nodules.
Output: adverse drug event
DISCUSSION: Patients with 5-FU-induced ectropion experience tender, red, scaled lids, making contact lens wear difficult.
Output: adverse drug event
We describe a case of fibrosing alveolitis, diagnosed by lung biopsy, in a patient receiving amiodarone which responded to corticosteroid therapy.
Output: adverse drug event
OBJECTIVE: To describe a case of severe skin necrosis resulting from peripheral intravenous administration of low-dose vasopressin in a patient with catecholamine-resistant septic shock.
Output: adverse drug event
With the negative viral serologies, the clinical picture was most consistent with an infectious mononucleosis-like syndrome produced by the minocycline ingestion.
Output: adverse drug event
Hepatotoxicity induced by cyproterone acetate: a report of three cases.
Output: adverse drug event
This unusual pattern of low-grade endometrial carcinoma adds to the spectrum of uterine neoplasia associated with tamoxifen therapy.
Output: adverse drug event
Extrapyramidal symptoms are well-documented complications of therapy with haloperidol, even when small doses are used.
Output: adverse drug event
Cholelithiasis and thrombosis of the central retinal vein in a renal transplant recipient treated with cyclosporin.
Output: adverse drug event
Bortezomib-induced paralytic ileus is a potential gastrointestinal side effect of this first-in-class anticancer proteasome inhibitor.
Output: adverse drug event
Twenty-four hours after the administration of gemcitabine, a symmetric, bullous, herpetiform eruption appeared on his trunk and upper limbs.
Output: adverse drug event
Nitrofurantoin-induced acute liver damage in pregnancy.
Output: adverse drug event
Two infants developed hyperkalemia shortly after cessation of prolonged ACTH therapy for infantile spasms.
Output: adverse drug event
In both patients the rippling phenomena worsened with pyridostigmine treatment but markedly improved after immunosuppression with azathioprine.
Output: adverse drug event
Successful desensitization to high-dose methotrexate after systemic anaphylaxis.
Output: adverse drug event
We conclude that neurosurgeons and neurologists should be aware of calcium antagonist--related ileus in patients treated with nimodipine.
Output: adverse drug event