niryuu/sni-each-converted huggingface dataset:
He had also developed elevated serum ammonia levels while on valproic acid.
Output: adverse drug event
There have been many reports of probable lithium-induced organic brain syndromes occurring when serum lithium levels are within or close to the therapeutic range.
Output: adverse drug event
She was administered metoclopramide because of nausea and, within 2 hours, developed agitation, dysarthria, diaphoresis, and a movement disorder.
Output: adverse drug event
Paradoxical ventricular tachycardia and fibrillation after intravenous bretylium therapy.
Output: adverse drug event
High-dose methylprednisolone in a pregnant woman with Crohn's disease and adrenal suppression in her newborn.
Output: adverse drug event
A case of basilar invagination which is thought to have arisen from the patient's intrauterine exposure to phenytoin is presented.
Output: adverse drug event
The case of a 29-year-old man suffering from falciparum malaria disease who got a reversible hearing loss from quinine therapy is presented.
Output: adverse drug event
Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome.
Output: adverse drug event
We report a case of biopsy proven myositis whose symptoms began within 10 days of receiving leuprolide acetate therapy for prostate cancer.
Output: adverse drug event
CONCLUSIONS: This is the second case report that describes gemcitabine-induced radiation recall in rectus abdominus muscles after gemcitabine-based radiation therapy.
Output: adverse drug event
Of particular interest in this patient is the fluctuation of the QT interval at a stable dose of methadone, suggesting that a single normal electrocardiogram (ECG) does not guarantee that the patient is not at risk of ventricular arrhythmias.
Output: adverse drug event
Within 3 weeks of beginning continuous daily isoniazid and rifampin therapy for pulmonary tuberculosis, a patient developed acute renal failure.
Output: adverse drug event
Progressive anemia following combination therapy with interferon-alpha and interleukin-2 in a patient with metastatic renal cell carcinoma.
Output: adverse drug event
PURPOSE: Topiramate-induced angle-closure glaucoma (TiACG) is believed to be related to its sulfonamide moiety.
Output: adverse drug event
A 57-year-old woman developed pulmonary sarcoidosis during therapy with interferon beta for advanced renal cell carcinoma metastatic to mediastinal lymph nodes.
Output: adverse drug event
We herein described an additional patient with BCR-ABL (ela2) positive acute lymphoblastic leukemia who developed tumor lysis syndrome after 10-day treatment with imatinib.
Output: adverse drug event
Myoclonus associated with continuous dobutamine infusion in a patient with end-stage renal disease.
Output: adverse drug event
The occurrence of neuromuscular blockade and the resulting potentiation of muscle relaxants during magnesium sulfate (MgSO4) administration is well known.
Output: adverse drug event
Stupor from lamotrigine toxicity.
Output: adverse drug event
Rapidly developing hyperglycemia during treatment with olanzapine.
Output: adverse drug event
Allergic contact dermatitis to compound tincture of benzoin.
Output: adverse drug event
Tetany in a child with AIDS receiving intravenous tobramycin.
Output: adverse drug event
Central pontine myelinolysis manifested by temporary blindness: a possible complication of lithium toxicity.
Output: adverse drug event
Carbamazepine-induced hyperammonemia.
Output: adverse drug event
To develop information on the relative rarity or frequency of neurologic worsening with the initiation of penicillamine therapy, we conducted a retrospective survey of 25 additional patients with Wilson's disease who met the criteria of presenting with neurologic disease and having been treated with penicillamine.
Output: adverse drug event
This is the first report of non-convulsive status epilepticus provoked by tiagabine in adolescent patients.
Output: adverse drug event
Progressive interstitial lung disease from prolonged methotrexate therapy.
Output: adverse drug event
Traumatic late flap dehiscence and Enterobacter keratitis following LASIK.
Output: adverse drug event
Multifocal inflammatory leukoencephalopathy associated with levamisole therapy.
Output: adverse drug event
OBJECTIVE: To describe two cases of rhabdomyolysis in patients taking lovastatin that were precipitated by the use of the newer macrolide antibiotics clarithromycin and azithromycin.
Output: adverse drug event
Subfulminant hepatitis B after infliximab in Crohn's disease: need for HBV-screening?
Output: adverse drug event
Suspected ciprofloxacin-induced interstitial nephritis.
Output: adverse drug event
In two patients, apomorphine remained effective in the morning, but increased the intensity of the dyskinesias in the afternoon.
Output: adverse drug event
After the dose of methylprednisolone was reduced from 40 mg to 20 mg i.v. q6h and shifted to other anti-asthma treatment by procaterol metered dose inhaler via spacer, the psychotic reaction disappeared a few hours later.
Output: adverse drug event
The literature search found 12 cases of radiation recall caused by gemcitabine.
Output: adverse drug event
CONCLUSION: The results suggest that olanzapine may be useful in treating patients with clozapine-induced granulocytopenia without the risk of recurrence of hematologic side effects.
Output: adverse drug event
He was diagnosed with possible serotonin syndrome; his symptoms resolved after clomipramine was stopped but before clozapine was restarted eight days later.
Output: adverse drug event
A case of priapism associated with trazodone is described.
Output: adverse drug event
Acute coronary syndromes can be associated with the infusion of rituximab.
Output: adverse drug event
Duodenal ulceration: a complication of tolazoline therapy.
Output: adverse drug event
Cholestyramine induced hyperchloremic metabolic acidosis.
Output: adverse drug event
When vague symptoms develop during desmopressin therapy, hyponatremia must be considered as part of the differential diagnosis.
Output: adverse drug event
Interstitial granulomatous dermatitis associated with darifenacin.
Output: adverse drug event
The epivodes of NMS occured under treatment with clozapine, risperidone, and amisulpride.
Output: adverse drug event
Adult respiratory distress syndrome after treatment with pegylated interferon alpha-2a and ribavirin.
Output: adverse drug event
OBJECTIVE: To determine the frequency of weight loss in patients treated with leflunomide for rheumatoid arthritis at an arthritis referral center.
Output: adverse drug event
This report highlights a case of drug-induced dysphagia in a patient receiving haloperidol for obsessive nocturnal thoughts and auditory disturbances.
Output: adverse drug event
METHODS: The patient required insulin desensitization for severe urticaria, angioedema, and occasional wheezing resulting from her insulin dose.
Output: adverse drug event
Beneficial effect of low-dose mianserin on fluvoxamine-induced akathisia in an obsessive-compulsive patient.
Output: adverse drug event
CONCLUSION: Hypersensitivity reaction should be considered in patients who develop recurrent eosinophilia and deterioration of pulmonary function following the use of tobramycin by inhalation or by intravenous administration.
Output: adverse drug event
In each of the three reported patients, alteration of eyelid appearance with deepening of the lid sulcus was evident as the result of topical bimatoprost therapy.
Output: adverse drug event
Within 24 hours of fluid restriction and cessation of desmopressin, her symptoms and hyponatremia resolved.
Output: adverse drug event
The rash seen in this patient, who was treated with cephalexin, may be similar to the rash seen with ampicillin treatment of patients with infectious mononucleosis.
Output: adverse drug event
Acute pancreatitis associated with danazol treatment for endometriosis.
Output: adverse drug event
OBJECTIVE: To test the hypothesis that tumor necrosis factor (TNF)-alpha may mediate the loss and the dedifferentiation of subcutaneous fat tissue in the insulin-induced lipoatrophies of a diabetic patient who presented extensive lesions.
Output: adverse drug event
Torsade de pointes represents a potential complication of chronic amiodarone therapy.
Output: adverse drug event
Both had impaired lung function and abnormal computed tomographic scans, and their condition improved when nitrofurantoin was withdrawn and corticosteroid treatment commenced.
Output: adverse drug event
The present report illustrates a rare case of refractory akathisia after interferon-alpha treatment and also that levodopa treatment would be theoretically and practically useful in reducing the neurotoxicity associated with interferon-alpha.
Output: adverse drug event
We report the first case of polymorphic ventricular tachycardia with normal QT interval associated with the oral use of levofloxacin in the absence of other etiologies known to cause these arrhythmias.
Output: adverse drug event
METHODS: Five cases of contact dermatitis due to budesonide, a nonhalogenated steroid, are described.
Output: adverse drug event
Peculiar nail-changes in a 70-year-old woman with rheumatoid arthritis occurring after approximately 1 year of penicillamine treatment are described.
Output: adverse drug event
We strongly suspect that this lethal anuria was mainly due to ifosfamide, occurring in a patient having received previous cisplatin chemotherapy and with poor kidney perfusion due to transient hypotension.
Output: adverse drug event
Herein we report four patients who underwent liver transplantation and developed neutropenia while receiving MMF.
Output: adverse drug event
Primary CNS lymphoma regressed on withdrawal of MM.
Output: adverse drug event
Fulminant hepatitis associated with disulfiram.
Output: adverse drug event
Hepatitis following cimetidine administration.
Output: adverse drug event
Propecia-associated bilateral cataract.
Output: adverse drug event
Occurrence of IDDM during interferon therapy for chronic viral hepatitis.
Output: adverse drug event
Multifocal electroretinographic abnormalities in ethambutol-induced visual loss.
Output: adverse drug event
Recognition of a potential drug-induced Fanconi syndrome is important when managing pediatric oncology patients previously treated with ifosfamide.
Output: adverse drug event
A patient developed restless legs symptoms paralleling the course of interferon-alpha (IFN alpha) therapy for chronic hepatitis C.
Output: adverse drug event
Acceleration of ventricular response to atrial flutter after intravenous adenosine.
Output: adverse drug event
Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis.
Output: adverse drug event
Clozapine-induced eosinophilia and switch to quetiapine in a patient with chronic schizophrenia with suicidal tendencies.
Output: adverse drug event
A 58-year-old man with advanced renal cell carcinoma developed grade 3 proteinuria (8.5 g/24 h) without microscopic hematuria or renal insufficiency five days after temsirolimus infusion.
Output: adverse drug event
Acute generalized exanthematous pustulosis induced by nimesulide.
Output: adverse drug event
A toxic encephalopathy characterized by depressed level of consciousness, marked irritability, and ataxia developed in seven children, 5 years of age and younger, following administration of an antiemetic combination of pentobarbital and pyrilamine maleate.
Output: adverse drug event
Clinical course of macular edema in two cases of interferon-associated retinopathy observed by optical coherence tomography.
Output: adverse drug event
In this case, CIPS was considered to be probably associated with cyclosporine according to the Naranjo probability scale.
Output: adverse drug event
Presented is a case of acute renal failure induced by acetazolamide therapy for glaucoma.
Output: adverse drug event
However, in order to avoid neuropathic side effects, patients under thalidomide therapy should be monitored every 6 months with nerve conduction studies while taking the drug.
Output: adverse drug event
A second possibility is an interaction between clarithromycin and isradipine, potentially increasing the hepatic toxicity of isradipine.
Output: adverse drug event
On the 3rd day, an inferior vena cava (IVC) filter was placed with a heparin flush, after which massive IVC thrombosis developed.
Output: adverse drug event
This is the first report of acute kidney injury due to zonisamide-induced DRESS/DIHS.
Output: adverse drug event
A complex pattern of melanonychia and onycholysis after treatment with pemetrexed for lung cancer.
Output: adverse drug event
Transient trazodone-induced hypomanic symptoms occurred in three depressed patients.
Output: adverse drug event
In this case, it was suspected that a combination of cigarette smoking, pulmonary fibrosis, and low-dose methotrexate therapy might have promoted the development of lung cancer.
Output: adverse drug event
This fourth type of cutaneous minocycline hyperpigmentation may be a variant of Type I, but based on clinical, pathological and microanalytical differences, appears to be a new entity.
Output: adverse drug event
Severe steroid-induced glaucoma following intravitreal injection of triamcinolone acetonide.
Output: adverse drug event
Methadone-induced myoclonus in advanced cancer.
Output: adverse drug event
The aim of this study was to describe the occurrence of acute coronary syndromes in 3 cases of rituximab infusions.
Output: adverse drug event
A young patient experienced marked sinus tachycardia while smoking marijuana and receiving therapeutic doses of nortriptyline.
Output: adverse drug event
Therefore, parenteral amiodarone was implicated as the cause of acute hepatitis in this patient.
Output: adverse drug event
Transtentorial herniation caused by an intracranial mass lesion following high-dose methotrexate.
Output: adverse drug event
Intracranial haemorrhage from a meningioma in a patient receiving aspirin prophylaxis: a case report.
Output: adverse drug event
One patient who received clindamycin had liver biopsy findings of marked cholestasis, portal inflammation, bile duct injury and bile duct paucity (ductopenia).
Output: adverse drug event
Posterior reversible encephalopathy syndrome associated with methotrexate neurotoxicity: conventional magnetic resonance and diffusion-weighted imaging findings.
Output: adverse drug event
We describe a 74-year-old man with rheumatoid arthritis (RA) who developed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) 1.5 months after commencement of mizoribin prescription when his arthritis was improved.
Output: adverse drug event
A 35-year-old female with borderline lepromatous (BL) leprosy who suffered from dapsone-induced erythroderma is reported.
Output: adverse drug event
A 64 year old woman with previous history of coronary stenting five days before was admitted in our institution for intracranial bleeding while receiving aspirin and clopidogrel.
Output: adverse drug event
A patient that received methadone for cancer-associated pain developed myoclonus as a side effect.
Output: adverse drug event
The present study describes a patient who had unusual weight fluctuation under corticosteroid and psychotropic treatment such as mianserin and aripiprazole.
Output: adverse drug event
Typical symptoms of active CD occurred 11, 12, and 26 months after start of etanercept therapy, respectively.
Output: adverse drug event
We attribute the clinical and radiographic findings to cytotoxic edema secondary to intrathecal methotrexate.
Output: adverse drug event
Several case reports of aplastic anemia with use of acetazolamide, and two cases with use of methazolamide, have appeared in the literature.
Output: adverse drug event
A 37-year-old woman with relapsing invasive vertebral aspergillosis received intravenous VRC and developed angio-oedema 10 days after starting therapy.
Output: adverse drug event
The case histories are presented of two patients who developed lung disease associated with the use of nitrofurantoin with histological features of bronchiolitis obliterans organising pneumonia (BOOP), a rare but recognised form of drug induced injury.
Output: adverse drug event
Acute myeloid leukemia and lung cancer occurring in a chronic lymphocytic leukemia patient treated with fludarabine and autologous peripheral blood stem-cell transplantation.
Output: adverse drug event
Although various manifestations of pentamidine-induced cardiotoxicity have been reported, to our knowledge, second-degree heart block associated with this agent has not been described.
Output: adverse drug event
We report a case of hyperpigmentation due to bleomycin treatment in a patient with acquired immune deficiency syndrome (AIDS).
Output: adverse drug event
PATIENTS: Three patients developed a reproductive endocrine disorder during treatment with valproate.
Output: adverse drug event
OBJECTIVE: To report the first five cases of amphotericin B overdose with secondary cardiac complications in a pediatric population.
Output: adverse drug event
Patients receiving amifostine who develop only fever should be evaluated for an adverse drug reaction, as well as for sepsis and fevers of neutropenia, and it may be necessary to discontinue the drug.
Output: adverse drug event
Ethambutol toxicity manifesting as acute onset psychosis.
Output: adverse drug event
Can magnesium sulfate therapy impact lactogenesis?
Output: adverse drug event
Perinatal vasoconstrictive renal insufficiency associated with maternal nimesulide use.
Output: adverse drug event
OBJECTIVE: To report a case of serotonin syndrome associated with interaction between fentanyl and citalopram, as evidenced by medication history, clinical features and reversal following discontinuation of fentanyl.
Output: adverse drug event
Antibiotic-associated colitis (pseudomembranous colitis) developed in four patients with spinal cord injury and taking oral trimethoprim-sulfamethoxazole.
Output: adverse drug event
In addition, there is a report on prolonged ECT seizure related to ciprofloxacin, which has an epileptogenic property with a similar action to beta-lactam antibiotics.
Output: adverse drug event
Captopril-induced acute reversible renal failure.
Output: adverse drug event
These multiple overlapping factors probably lead to rhabdomyolysis in a minority of patients receiving vasopressin infusion.
Output: adverse drug event
Baclofen withdrawal syndrome resulting from underdosing of oral baclofen should be considered as a potential source of prolonged fever in the intensive care unit.
Output: adverse drug event
Disseminated tuberculous lesions post intravesical BCG therapy are rare but need to be identified and treated quickly.
Output: adverse drug event
Acute endophthalmitis following intravitreal bevacizumab (Avastin) injection.
Output: adverse drug event
Cardiac toxicity related to BCNU has not been described well.
Output: adverse drug event
To our knowledge, this case is the first published report of levofloxacin-induced TEN.
Output: adverse drug event
Exacerbation of anthracycline-induced early chronic cardiomyopathy with ATRA: role of B-type natriuretic peptide as an indicator of cardiac dysfunction.
Output: adverse drug event
The occurrence of severe AIHA in CLL patients treated with fludarabine has been reported by several authors.
Output: adverse drug event
RESULTS: Replacing valproate with lamotrigine resulted in a decrease in serum testosterone concentrations in all 3 women.
Output: adverse drug event
A case of liver damage following treatment with Danazol for fibrocystic breast disease is reported.
Output: adverse drug event
Central nervous system toxicity associated with meperidine use in hepatic disease.
Output: adverse drug event
Sweet's syndrome associated with sargramostim (granulocyte-macrophage colony stimulating factor) treatment.
Output: adverse drug event
OBJECTIVE: To our knowledge, this is the first published case report of an adolescent girl with a mitochondrial disorder and depression who displayed both new-onset psychotic and increased mood symptoms during treatment with risperidone.
Output: adverse drug event
In conclusion, this case strongly suggests that gliclazide can induce acute icteric liver necro-inflammation which may be misdiagnosed clinically as acute viral hepatitis.
Output: adverse drug event
The toxic effects of methotrexate included elevated liver transaminases (3/4), nausea (2/4), abdominal pain (2/4), bone pain (2/4), mild neutropenia (1/4), and mild pruritus (1/4).
Output: adverse drug event
Methotrexate-induced liver cirrhosis.
Output: adverse drug event
OBJECTIVE: To report the safe use of fluorouracil in a patient with breast cancer who had allergic reactions to capecitabine.
Output: adverse drug event
Bowel perforation associated with intraperitoneal chromic phosphate instillation.
Output: adverse drug event
Mefloquine-associated hypoglycaemia in a cachectic AIDS patient.
Output: adverse drug event
Due to the severity of the rash, temozolomide was permanently discontinued.
Output: adverse drug event
Type I second-degree AV block (Mobitz type I, Wenckebach AV block) during ritodrine therapy for preterm labor.
Output: adverse drug event
Rebound hyperglycemia following overdosing of insulin in cats with diabetes mellitus.
Output: adverse drug event
She died within six weeks of developing congestive heart failure coupled with liver failure due to haemosiderosis despite regular use of desferrioxamine.
Output: adverse drug event
DIAGNOSIS: Interferon alpha-2b-induced cardiomyopathy.
Output: adverse drug event
Anaphylaxis from isoniazid is a possible side effect to this commonly prescribed antibiotic.
Output: adverse drug event
Arterial hypertension associated with topical ocular use of phenylephrine in dogs.
Output: adverse drug event
ARDS is rarely associated with rituximab infusion for lympho-proliferative disorders, but it should be considered by those administering rituximab, especially when a patient develops severe pulmonary symptoms soon after infusion.
Output: adverse drug event
Severe autoimmune hemolytic anemia following rituximab therapy in a patient with a lymphoproliferative disorder.
Output: adverse drug event
OBJECTIVE: To report a case of neuroleptic malignant syndrome (NMS) associated with fluphenazine in a schizophrenic patient and review the literature related to this condition.
Output: adverse drug event
However, there remain questions concerning whether these drugs, especially methimazole (MMI), may be associated with aplasia cutis congenita (ACC) and how best to avoid impairment of fetal thyroid function during their use.
Output: adverse drug event
PATIENTS: Two patients, ages 40 and 51 years, undergoing treatment with interferon alfa for malignant neoplasms experienced sudden bilateral, sequential visual loss with disc-related field defects and segmental optic disc edema.
Output: adverse drug event
In case no. 2, the pathogenic mechanism seemed to be persistent light reaction preceded by systemic photoallergy, as he had taken mequitazine for 6 months, and there were strong positive photopatch test results with immediate erythema reaction, cross-reaction to promethazine, decreased MED to both UVA and UVB, and persistence of the photosensitivity over a 3-year follow-up period after discontinuation of the mequitazine.
Output: adverse drug event
Despite the known pulmonary side effects of nitrofurantoin, there is no report of this toxicity occurring in pregnant patients.
Output: adverse drug event
CONCLUSIONS: This study confirmed that in most patients MTX-induced liver cirrhosis is not aggressive.
Output: adverse drug event
Fatal interstitial lung disease after erlotinib administration in a patient with radiation fibrosis.
Output: adverse drug event
A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency who developed a syringotropic hypersensitivity reaction after 9 months of therapy with infliximab and leflunomide is described.
Output: adverse drug event
However, prolongation of 5-FU half-life and an increase in INR have been reported with the concurrent use of 5-FU and warfarin.
Output: adverse drug event
Carbamazepine toxicity following Oxybutynin and Dantrolene administration: a case report.
Output: adverse drug event
Seizures associated with fluoxetine therapy.
Output: adverse drug event
Thiopurine methyltransferase deficiency occurs at a frequency of one in 300 and is associated with profound myelosuppression after a short course of azathioprine.
Output: adverse drug event
This report describes a case of bilateral ptosis induced by chloroquine.
Output: adverse drug event
However, dermatologists should be cautious about a photosensitivity reaction induced by mequitazine or other phenothiazine-derivative drugs.
Output: adverse drug event
We describe a relatively healthy, 9-year-old boy who developed a CA-MRSA skin and soft tissue infection and was treated with TMP-SMX.
Output: adverse drug event
A 73 year-old patient with Wolff-Parkinson-White syndrome and paroxysmic supraventricular tachycardia developed an acute reversible encephalopathy within 15 days of initiation of flecainide.
Output: adverse drug event
Sulfasalazine-induced lung disorder is an extremely rare entity which must be considered in all ulcerative colitis patients while on sulfasalazine therapy, despite the absence of pulmonary symptomatology.
Output: adverse drug event
In all cases, drugs in addition to quetiapine were detected, but in cases #1 and #2, the cause of death was considered to be a quetiapine overdose and the other drugs were not considered to be contributory.
Output: adverse drug event
This eruption appears to be a distinct cutaneous toxicity of PLD.
Output: adverse drug event
Capecitabine-induced headache responding to diltiazem.
Output: adverse drug event
Syncope induced by propranolol in hypertrophic cardiomyopathy.
Output: adverse drug event
Due to the increasing use of TMP-SMX in children, clinicians should be aware of this potentially life-threatening, immunemediated hypersensitivity reaction.
Output: adverse drug event
In all cases, seizures were controlled by withdrawal of phenytoin and reduction of drug levels.
Output: adverse drug event
The development of erythroid leukemia plus carcinoma in these two men suggests mutagenic change secondary to cyclophosphamide therapy.
Output: adverse drug event
Possible linkage of amprenavir with intracranial bleeding in an HIV-infected hemophiliac.
Output: adverse drug event
OBJECTIVE: To describe a patient with asymptomatic bronchial asthma and hypertension who developed an acute asthma attack after receiving sustained-release verapamil.
Output: adverse drug event
To our knowledge, this is the first report of insulin-induced lipohypertrophy with detailed histological examinations.
Output: adverse drug event
Aripiprazole-induced hiccups: a case report.
Output: adverse drug event
Diagnosis of sclerosing glomerulonephritis occurred in this patient during anastrozole use, suggesting a newly defined side effect of anastrozole.
Output: adverse drug event
Reversal of gold-induced neutropenia with granulocyte colony-stimulating factor (G-CSF).
Output: adverse drug event
We report a case of intrathecal methotrexate neurotoxicity manifesting as left arm weakness and aphasia.
Output: adverse drug event
This regimen could prove useful for other patients who develop hypersensitivity reactions to carboplatin and allow therapy to continue.
Output: adverse drug event
A case of severe aplastic anemia secondary to treatment with lenalidomide for multiple myeloma.
Output: adverse drug event
A case of SIADH induced by mizoribin administration.
Output: adverse drug event
We report a case of torsade de pointes following a single oral dose of amiodarone (1400 mg or 30 mg kg-1) administered after short intravenous loading for prevention of paroxysmal atrial flutter.
Output: adverse drug event
Hashimoto's disease during interferon-alpha therapy in a patient with pre-treatment negative anti-thyroid autoantibodies and with the specific genetic susceptibility to the thyroid disease.
Output: adverse drug event
While undergoing treatment with albendazole, he developed worsening diarrhea with abdominal pain and fever.
Output: adverse drug event
Early overanticoagulation with acenocoumarol due to a genetic polymorphism of cytochrome P450 CYP2C9.
Output: adverse drug event
The patient suffered a life-threatening anaphylactoid reaction to amifostine.
Output: adverse drug event
METHODS: A 55-year-old woman became stuporous after overdose with lamotrigine (LTG) and valproic acid (VPA) tablets.
Output: adverse drug event
CASE SUMMARY: A 58-year-old white woman developed fulminant liver failure while being treated with the macrolide antibiotic clarithromycin for pneumonia.
Output: adverse drug event
Acute renal failure during lisinopril and losartan therapy for proteinuria.
Output: adverse drug event
The main side-effects of Lp-TAE combined with HT were low-grade fever, localized pain, myelo-suppression and liver dysfunction, but these were transient and eventually disappeared.
Output: adverse drug event
Pulmonary toxicity with mefloquine.
Output: adverse drug event
A 64-year-old man presented with proteinuria during postoperative interferon (IFN)-beta therapy against malignant melanoma.
Output: adverse drug event
Ramipril-induced cutaneous vasculitis is particularly rare and our case was atypical because the patient had tolerated lisinopril before.
Output: adverse drug event
Myoclonus and seizures in a patient with parkinsonism: induction by levodopa and its confirmation on SEPs.
Output: adverse drug event
We report a 44-year-old woman with t-MDS (refractory anemia with excess blasts) following treatment of recurrent anaplastic astrocytoma with temozolomide (TMZ).
Output: adverse drug event
The use of methotrexate (MTX) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease.
Output: adverse drug event
Amiodarone was discontinued, and thyrotoxicosis gradually abated.
Output: adverse drug event
We report a case of a 60-year-old woman affected by squamous lung carcinoma, who developed paroxysmal supraventricular tachycardia during cisplatin and etoposide combination chemotherapy.
Output: adverse drug event
BACKGROUND: Gemcitabine has mild renal toxicity, but cases of gemcitabine-associated hemolytic-uremic syndrome (HUS) have been reported.
Output: adverse drug event
Salicylate-induced hepatotoxicity is reviewed.
Output: adverse drug event
Acute erythroid leukemia after cyclophosphamide therapy for multiple myeloma: report of two cases.
Output: adverse drug event
Probable early acute hepatitis with parenteral amiodarone.
Output: adverse drug event
Acute renal failure in a child associated with acyclovir.
Output: adverse drug event
We describe a case of prolonged terbinafine-induced cholestatic liver disease.
Output: adverse drug event
Recurrent hyponatremia associated with citalopram and mirtazapine.
Output: adverse drug event
Syndrome of inappropriate secretion of ADH (SIADH) following cisplatin administration in a pulmonary adenocarcinoma patient with a malignant pleural effusion.
Output: adverse drug event
Itraconazole-related increased vincristine neurotoxicity: case report and review of literature.
Output: adverse drug event
In this case senna was likely the cause of a subacute cholestatic hepatitis exemplifying again the potential role of herbal related liver injury.
Output: adverse drug event
We conclude that while thrombocytopenia and schistocytosis can be seen in quinine-associated TTP/HUS, the pathophysiology seems to be distinct from that seen in most cases of idiopathic TTP (i.e., severely decreased ADAMTS13 with an inhibitor).
Output: adverse drug event
We experienced 2 cases of mequitazine-induced photosensitivity reaction in patients who took mequitazine for their dermatologic problems.
Output: adverse drug event
Anti-tuberculous drugs had been stopped on the 2nd day of therapy due to development of optic neuritis secondary to ethambutol administration at another hospital.
Output: adverse drug event
METHODS/RESULTS: This paper presents a new case of rifabutin uveitis and a review of the various published reports to date.
Output: adverse drug event
Isoniazid causing breast tissue enlargement has been very rarely reported.
Output: adverse drug event
We report on three patients who developed acute liver damage during therapy with itraconazole, and in whom liver biopsy specimens were obtained.
Output: adverse drug event
Although moderate myelosuppression is not uncommonly seen in patients treated with lenalidomide, aplastic anemia has not previously been reported to be associated with this agent.
Output: adverse drug event
Agranulocytosis is a rare adverse effect associated with prolonged vancomycin therapy, and is potentially serious, especially in end stage renal disease (ESRD) patients.
Output: adverse drug event
Nodular scleritis following alendronate therapy.
Output: adverse drug event
Syringotropic hypersensitivity reaction associated with infliximab and leflunomide combination therapy in a child with psoriatic arthritis.
Output: adverse drug event
Physicians should be aware that indinavir nephrolithiasis may cause papillary necrosis.
Output: adverse drug event
Many clinicians appear to be concerned about the potential hepatotoxicity of the opiate antagonist naltrexone (NTX) and this may be one reason why it is not used more widely in treating both heroin and alcohol abusers.
Output: adverse drug event
Nonspecific but significant abnormalities have been described in the infants of women treated with disulfiram in the first trimester of their pregnancies.
Output: adverse drug event
Such anagen effluvium with lichenoid eruption following INH therapy has not been observed previously.
Output: adverse drug event
It should be emphasized that the recurrence of nephrotic syndrome was observed after the following chemotherapy, including M-CSF, whereas the bone marrow still remained completely remitted.
Output: adverse drug event
Tumor-volume increase at beginning of primary treatment with topical interferon alpha 2-beta in a case of conjunctiva-cornea intraepithelial neoplasia.
Output: adverse drug event
Isoniazid-induced anaphylaxis.
Output: adverse drug event
Since elevated cortisol levels in Cushing's disease poses a threat for pancreatitis, there is a possibility that patients with Cushing's disease might be more prone to acute pancreatitis following propofol administration.
Output: adverse drug event
Treatment of lithium-induced diabetes insipidus with amiloride.
Output: adverse drug event
Hence, hyperthyroidism induced by IFN-alpha could correspond to the first phase of silent thyroiditis, to Graves' disease or to the succession of both.
Output: adverse drug event
Less common adverse events to dapsone include the idiosyncratic reactions of leukopenia and agranulocytosis, cutaneous eruptions, peripheral neuropathy, psychosis, toxic hepatitis, cholestatic jaundice, nephrotic syndrome, renal papillary necrosis, severe hypoalbuminemia without proteinuria, an infectious mononucleosis-like syndrome, and minor neurological and gastrointestinal complaints.
Output: adverse drug event
Gemcitabine-related radiation recall preferentially involves internal tissue and organs.
Output: adverse drug event
Generalized pustular psoriasis precipitated by trazodone in the treatment of depression.
Output: adverse drug event
We report on a child with fatal valproate-related hepatotoxic effects despite this supplementation.
Output: adverse drug event
Retrospectively, bucillamine was believed to be the cause of the giant hypertrophy because of its structural similarity to D-penicillamine, which was the subject of an abundance of reports of mammary hyperplasia.
Output: adverse drug event
We report a case of a patient with rheumatoid arthritis treated with low-dose methotrexate (15 mg/week) who developed infection with both M. tuberculosis and M. chelonae after the revision of a prosthetic hip.
Output: adverse drug event
The authors conclude that among patients taking high doses of oral niacin only those who experience visual symptoms need to be ophthalmologically evaluated.
Output: adverse drug event
Retinopathy in hepatitis C patients due to combination therapy with pegylated interferon and ribavirin.
Output: adverse drug event
Protamine-induced fatal anaphylaxis.
Output: adverse drug event
Gynaecomastia is a rarely reported adverse drug reaction due to isoniazid therapy.
Output: adverse drug event
We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide.
Output: adverse drug event
DISCUSSION: Anaphylactoid reactions have been described previously with cisplatin administration.
Output: adverse drug event
Lethal anuria complicating high dose ifosfamide chemotherapy in a breast cancer patient with an impaired renal function.
Output: adverse drug event
In patients with cirrhosis, the metabolism of meperidine is decreased, leading to accumulation of the parent drug and possible CNS depressive effects similar to hepatic encephalopathy.
Output: adverse drug event
Physicians should be aware of the potentially lethal side effects of dapsone.
Output: adverse drug event
To our knowledge, no prior cases of penicillamine-induced TTP in RA have been reported.
Output: adverse drug event
We present the cases of two female patients diagnosed with relapsing-remitting multiple sclerosis (RRMS) who developed inflammatory musculoskeletal manifestations, following IFN-beta therapy.
Output: adverse drug event
We presented a patient with status asthmaticus treated with a combination of theophylline and prednisone who developed a perforated gastric ulcer.
Output: adverse drug event
The first known report of quetiapine exacerbating OCS in a 43-year-old man with obsessive-compulsive disorder (OCD), trichotillomania, delusional disorder and bipolar II disorder is presented.
Output: adverse drug event
CONCLUSIONS: Symptoms and pathologic changes of colitis are associated with exposure to rofecoxib.
Output: adverse drug event
Three of these patients had convulsions attributed to imipenem/cilastatin; 3.6% of the patients had seizure, or 2% of imipenem/cilastatin administrations was followed by a seizure attack.
Output: adverse drug event
A 51-yr-old nonsmoking male patient without any history of previous allergies, asthma, hay fever, or urticaria developed attacks of asthma when captopril was added to the nadolol and dyazide treatment for his high blood pressure.
Output: adverse drug event
The polycystic changes disappeared from the ovaries in 2 of the women after valproate therapy was discontinued, and the 2 women who had gained weight and developed amenorrhea while being treated with valproate lost weight and resumed menstruating after the change in medication.
Output: adverse drug event
We present the first case of WES in an infant born to a mother taking haloperidol during her pregnancy.
Output: adverse drug event
Oral 25-hydroxyvitain D3 in treatment of osteomalacia associated with ileal resection and cholestyramine therapy.
Output: adverse drug event
We report three cases of IFN beta induced hepatitis in MS and discuss the pathology findings and possible mechanisms of drug-induced liver injury.
Output: adverse drug event
Based on these findings, the patient was diagnosed with diabetes insipidus secondary to lithium therapy and was treated successfully with amiloride.
Output: adverse drug event
Lichen planus and acne provoked by gold.
Output: adverse drug event
He was started on digoxin, 0.25 mg daily, because of echocardiographically demonstrated left ventricular dilatation and functional impairment; he died of ventricular fibrillation 15 days later.
Output: adverse drug event
In the absence of mucositis or diarrhea, severe dermatologic toxicity following a single low dose of the drug suggests an 'allergic' or acute hypersensitivity reaction to MTX in this patient.
Output: adverse drug event
Benzocaine-induced methemoglobinemia has been reported in man, dogs, and cats.
Output: adverse drug event
A review of the literature showed no previous description of this pattern in benzodiazepine coma.
Output: adverse drug event
A 62-year-old Indian with diabetic nephropathy controlled with metformin, developed miliary tuberculosis for which he was treated with rifampicin, isoniazid and ethambutol.
Output: adverse drug event
Sensorineural hearing loss due to quinine therapy for malaria has frequently been mentioned in the literature but has not been a subject of research during the last decades.
Output: adverse drug event
OBJECTIVE: To present a single case of zuclopenthixol-induced priapism and a literature review.
Output: adverse drug event
MATERIALS AND METHODS: We present two cases of significant morbidity related to primary and secondary perforation of the bladder following two instillations of epirubicin.
Output: adverse drug event
Intravenous azithromycin-induced ototoxicity.
Output: adverse drug event
In one child, a second course of carbamazepine resulted in a return of the dystonia.
Output: adverse drug event
CONCLUSION: This is, to our knowledge, the first report of severe myelopathy following accidental intrathecal administration of doxorubicin.
Output: adverse drug event
However, as the use of hepatitis B vaccination is growing, adverse side effects, including mental nerve neuropathy, should be observed with an increased frequency.
Output: adverse drug event
Autoimmune thyroid disease is a common side-effect of interferon-alpha (IFN-alpha) treatment of viral hepatitis C.
Output: adverse drug event
An immediate hemolytic reaction induced by repeated administration of oxaliplatin.
Output: adverse drug event
Retinal abnormalities, including retinal hemorrhage and "cotton-wool" spots, often occur within the first 8 weeks in the course of interferon therapy in patients with chronic hepatitis C.
Output: adverse drug event
Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.
Output: adverse drug event
A case of polymyositis with dilated cardiomyopathy associated with interferon alpha treatment for hepatitis B.
Output: adverse drug event
Except hypothyroidism after radioiodine treatment (euthyroid under substitutional therapy), she suffered from no other diseases.
Output: adverse drug event
The authors report 2 cases of renal damage associated with lithium carbonate treatment.
Output: adverse drug event
We describe two cases of sulfadiazine-induced crystalluria and renal failure in patients with acquired immunodeficiency syndrome, review the pertinent literature, and discuss the pathogenesis.
Output: adverse drug event
PURPOSE: We report an unusual paradoxical effect of brimonidine.
Output: adverse drug event
Thrombocytosis under ciprofloxacin and tazobactam/piperacillin.
Output: adverse drug event
A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck developed severe skin rash and bone marrow aplasia 4 and 7 days, respectively, following a single dose of 40 mg/m2 methotrexate (MTX).
Output: adverse drug event
We present a case of an elderly woman with a pre-existing history of ischaemic heart disease, who was treated with venlafaxine, and developed acute myocardial ischaemia within the first week of treatment.
Output: adverse drug event
One week after the initial-dose of adalimumab (160 mg), which was initiated due to an acute exacerbation of Crohn's disease, the patient developed a fulminant cardiomyopathy.
Output: adverse drug event
Phenobarbital hepatotoxicity in an 8-month-old infant.
Output: adverse drug event
This represents the first report of nonconvulsive status epilepticus induced by ifosfamide.
Output: adverse drug event
The occurrence of acute hepatitis is best known for ketoconazole.
Output: adverse drug event
A twelve year-old-girl with idiopathic partial epilepsy with secondary generalization, developed acute psychosis 10 days after the administration of levetiracetam.
Output: adverse drug event
ARDS has been associated with the administration of other monoclonal antibodies, such as infliximab, gemtuzumab ozogamicin, and OKT3 and is believed to be directly mediated by release of proinflammatory cytokines.
Output: adverse drug event
The authors suggest that fluoxetine-induced akathisia may be caused by serotonergically mediated inhibition of dopaminergic neurotransmission and that the pathophysiology of fluoxetine-induced akathisia and tricyclic antidepressant-induced "jitteriness" may be identical.
Output: adverse drug event
Here we report ramipril-induced cutaneous vasculitis in a patient who required steroid therapy to control it.
Output: adverse drug event
Tiagabine overdose causes an unusual array of neurological symptoms, many similar to reported adverse effects during therapeutic use.
Output: adverse drug event
Scleroderma in association with the use of bleomycin: a report of 3 cases.
Output: adverse drug event
The increased libido disappeared after fluvoxamine was discontinued.
Output: adverse drug event
Renal hypophosphatemia in this patient was caused by the erroneous intake of 1 g doxycycline.
Output: adverse drug event
We present the management of agranulocytosis and neutropenic sepsis secondary to carbimazole with recombinant human granulocyte colony stimulating factor (G-CSF).
Output: adverse drug event
Acute severe intoxication with carbamazepine is associated with seizures, coma and respiratory depression.
Output: adverse drug event
Complete remission of the nephrosis occurred after discontinuation of hydroxychloroquine therapy.
Output: adverse drug event
We describe a patient with transitional cell carcinoma of the renal pelvis who developed respiratory dysfunction and an abnormal chest x-ray with diffuse interstitial opacities while on chemotherapy with piritrexim, a methotrexate analog.
Output: adverse drug event
Intrathecal methotrexate-induced acute cerebellar syndrome.
Output: adverse drug event
Discontinuation of simvastatin and cyclosporine resulted in resolution of rhabdomyolysis and normalization of renal function.
Output: adverse drug event
When the disease recurred conventional amphotericin B was used again, but had to be stopped because of severe side effects.
Output: adverse drug event
Flare of Kaposi's sarcoma (KS) is well described in immunosuppressed patients treated with corticosteroids and rituximab, but has not yet been reported during treatment with imatinib.
Output: adverse drug event
INTRODUCTION: Although gefitinib used for the treatment of non-small-cell lung cancer is a well-known cause of interstitial lung disease (ILD), few case reports on erlotinib-induced ILD have been issued.
Output: adverse drug event
We present a case of respiratory failure occurring in a woman at 16 weeks' gestation who was being treated with nitrofurantoin for a urinary tract infection.
Output: adverse drug event
Because etoposide-induced pulmonary toxicity is an uncommon but serious adverse event, clinicians must be vigilant about the possibility of it, so that the optimal treatment can start as soon as possible.
Output: adverse drug event
The patient described in this paper was a 78-year-old diabetic man who developed oral lesions of PV following institution of glibenclamide therapy.
Output: adverse drug event
Nonsustained polymorphous ventricular tachycardia during amiodarone therapy for atrial fibrillation complicating cardiomyopathy.
Output: adverse drug event
This compound, used by adults in the child's home, had caused accidental theophylline poisoning, mimicking diabetic ketoacidosis.
Output: adverse drug event
Lithium-associated transient thyrotoxicosis in 4 Chinese women with autoimmune thyroiditis.
Output: adverse drug event
Rapid identification of speech loss linked to FK506 may be important because reduction or cessation of the drug may be associated with reverse of speech loss.
Output: adverse drug event
Reversible findings of restricted diffusion in 5-fluorouracil neurotoxicity.
Output: adverse drug event
Carbamazepine induced right bundle branch block in a Greenlandic patient.
Output: adverse drug event
However, there are few reports in the literature of ampicillin as a cause of acute interstitial nephritis.
Output: adverse drug event
Reversible corneal keratinization following trabeculectomy and treatment with 5-fluorouracil.
Output: adverse drug event