niryuu/sni-each-converted huggingface dataset:
CASE SUMMARY: A 46-year-old African-American man experienced recurrent grand mal seizures during intravenous infusion of amphotericin B, then petit mal seizures as the infusion was stopped and the drug concentrations decreased with time.
Output: amphotericin B
CONCLUSIONS: Amphotericin B seems to be the probable cause of the seizures.
Output: Amphotericin B
Despite administration of phenytoin and lorazepam, the seizures persisted and occurred only during amphotercin B administration.
Output: amphotercin B
Didanosine also has a potential for inducing seizures.
Output: Didanosine
OBJECTIVE: To report a case of multiple episodes of seizure activity in an AIDS patent following amphotericin B infusion.
Output: amphotericin B
The time course of events suggested that amphotericin B was the cause of the seizures in this AIDS patient.
Output: amphotericin B
To date, only three cases of seizures associated with amphotericin B have been reported in the literature, but healthcare providers should be aware of the potential for this rare adverse effect.
Output: amphotericin B
Vocal cord paralysis as a consequence of peritonsillar infiltration with bupivacaine.
Output: bupivacaine
We present the case of a 5-year-old girl who developed bilateral vocal cord paralysis following preoperative peritonsillar bupivacaine infiltration.
Output: bupivacaine
A 53 year old Greenlandic male was admitted twice over a period of 4 years with a new complete right bundle branch block after ingestion of 10 g and 4 g of carbamazepine respectively.
Output: carbamazepine
Carbamazepine induced right bundle branch block in a Greenlandic patient.
Output: Carbamazepine
Cicatricial entropion associated with chronic dipivefrin application.
Output: dipivefrin
CONCLUSIONS: Cicatrization in the substantia propria of the conjunctiva by excessive lymphocytic infiltration after topically administered antiglaucoma drugs including dipivefrin is a possible mechanism of action for entropion.
Output: dipivefrin
Nine eyes from 6 patients, 74 years to 90 years of age, referred by ophthalmologists for repair of cicatricial entropion after at least 2 years of twice-a-day application of dipivefrin.
Output: dipivefrin
PURPOSE: To report patients who presented to the oculoplastics department for repair of cicatrical entropion after topical use of dipivefrin.
Output: dipivefrin
The 3-week sulphasalazine syndrome strikes again.
Output: sulphasalazine
Interestingly, the use of carboplatin (CBDCA) and VDS in the subsequent treatment course was well tolerated indicating that the SIADH was most likely to have been induced by administration of CDDP.
Output: CDDP
After extensive neurological 'work up', we realized that the anisocoria was related to the transdermal scopolamine patch that we had prescribed for weaning off the opioid.
Output: scopolamine
Anisocoria from transdermal scopolamine.
Output: scopolamine
De novo absence status of late onset following withdrawal of lorazepam: a case report.
Output: lorazepam
The aim of this report is to describe the clinical and electroencephalographic findings seen in an elderly woman without previous history of seizures who developed a nonconvulsive generalized status epilepticus following acute withdrawal of lorazepam.
Output: lorazepam
Early recognition of hereditary motor and sensory neuropathy type 1 can avoid life-threatening vincristine neurotoxicity.
Output: vincristine
Recognizing early signs of HMSN, such as areflexia and pes cavus deformity, can prevent severe neurotoxicity of polychemotherapy by avoiding vincristine.
Output: vincristine
The disease predisposes to severe vincristine neurotoxicity.
Output: vincristine
We report a 31-year-old women with recurrent Hodgkin's lymphoma and unrecognized HMSN-1 who developed severe motor neuropathy 3 weeks after the first cycle of treatment including 2 mg of vincristine.
Output: vincristine
We describe a patient who had a systemic allergic contact dermatitis to 8-MOP develop during her second course of PUVA treatment for psoriasis.
Output: 8-MOP
CONCLUSION: Although a definite association has not been proven, clinicians should be aware of the possibility of agranulocytosis while using quetiapine.
Output: quetiapine
METHOD: We describe three case-reports concerning haematological adverse effects of quetiapine.
Output: quetiapine
CONCLUSIONS: There is very little published information regarding ofloxacin-induced toxic epidermal necrolysis.
Output: ofloxacin
It is hoped that this case report creates awareness that ofloxacin-induced toxic epidermal necrolysis is possible.
Output: ofloxacin
OBJECTIVE: To report a fatal case of toxic epidermal necrolysis in a man who was treated with oral ofloxacin for epididymitis.
Output: ofloxacin
Ofloxacin: a probable cause of toxic epidermal necrolysis.
Output: Ofloxacin
A boy with chronic neutropenia and recurrent inflammatory skin lesions developed multiple erythematous nodules following administration of G-CSF.
Output: G-CSF
A girl with cystic fibrosis and cyclic neutropenia developed an erythematous papular eruption without fever or neutrophilia 7 months after commencing therapy with G-CSF.
Output: G-CSF
There is a putative role of liothyronine administration in precipitating or activating hyperthyroidism.
Output: liothyronine
Triiodothyronine-induced thyrotoxicosis in ophthalmic Graves disease.
Output: Triiodothyronine
Pulmonary toxicity with mefloquine.
Output: mefloquine
This report presents a case of acute lung injury developing within hours after administration of mefloquine for a low-level Plasmodium falciparum malaria, which was persistent despite halofantrine therapy.
Output: mefloquine
An adult male presented with central blindness after ingesting methanol.
Output: methanol
Reversal of severe methanol-induced visual impairment: no evidence of retinal toxicity due to fomepizole.
Output: methanol
Extra caution should be taken in using octreotide or its long-acting analog in patients otherwise predisposed to intrahepatic bile stasis.
Output: octreotide
Hepatolithiasis (intrahepatic stone) during octreotide therapy for acromegaly: a case report.
Output: octreotide
This is the first reported case of hepatolithiasis during octreotide therapy.
Output: octreotide
We report a case of hepatolithiasis (intrahepatic stone) complicated by gram-negative sepsis in a 37 year old male with acromegaly being treated with octreotide.
Output: octreotide
However, in the mid-to-late 1980s, a series of letters to the editor and case reports announced an association between tamoxifen therapy in women with breast cancer and the development of endometrial carcinoma.
Output: tamoxifen
In this healthy population, the relative risk of developing endometrial carcinoma in the tamoxifen arm was 2.54, although when stratified by age, in women over 50, the risk grew to 4.01.
Output: tamoxifen
INH, which is a leading cause of drug eruptions in the above group of drugs was withdrawn.
Output: INH
Linear IgA bullous dermatosis occurring after carbamazepine.
Output: carbamazepine
We report a patient who experienced LABD shortly after starting carbamazepine therapy.
Output: carbamazepine
Serotonin syndrome caused by selective serotonin reuptake-inhibitors-metoclopramide interaction.
Output: metoclopramide
A patient suffering from a rare enzyme deficiency developed a malignant neuroleptic syndrome after having been treated with one single dose of haloperidol.
Output: haloperidol
BACKGROUND: reports on delated cutaneous reactions to captopril have been seldom reported.
Output: captopril
Captopril is an angiotensin-converting enzyme (ACE) inhibitor and their cutaneous side-effects are documented, but little has been published concerning the usefulness of patch test when they occur.
Output: Captopril
Dermatitis to captopril.
Output: captopril
We presented the case of a patient who developed a cutaneous reaction induced by captopril with positive patch test.
Output: captopril
A 62-year-old Caucasian man with atrial fibrillation who was taking warfarin reported an episode of hematochezia; his international normalized ratio (INR) was 1.74.
Output: warfarin
Warfarin-associated bleeding complication saved life.
Output: Warfarin
Warfarin-associated bleeding generally is considered deleterious; however, in our patient it unmasked an early stage of colon cancer and thus may have saved the patient's life.
Output: Warfarin
Polymyositis is a rare complication of interferon alpha treatment as a result of immune-modulating role of the drug itself.
Output: interferon alpha
To treat hepatitis B, interferon alpha was administered until the proximal muscle weakness developed.
Output: interferon alpha
Long-term follow-up after neoplastic seeding complicating percutaneous ethanol injection for treatment of hepatocellular carcinoma.
Output: ethanol
We describe a case of subcutaneous metastasis along the needle track after percutaneous ethanol injection (PEI) for treatment of hepatocellular carcinoma.
Output: ethanol
Aggressive endometrial carcinoma in a breast cancer patient treated with tamoxifen with normal transvaginal ultrasonography.
Output: tamoxifen
We described a very atypical case of a high stage, high grade endometrial cancer associated with tamoxifen in a 64-year-old woman with a past history of breast cancer.
Output: tamoxifen
Hepatotoxicity related to itraconazole: report of three cases.
Output: itraconazole
METHODS: Three patients with apparent itraconazole-induced liver injury were studied.
Output: itraconazole
The occurrence of acute hepatitis is best known for ketoconazole.
Output: ketoconazole
We report on three patients who developed acute liver damage during therapy with itraconazole, and in whom liver biopsy specimens were obtained.
Output: itraconazole
We suggest that itraconazole should be added to the list of drugs that may be responsible for a drug-induced vanishing bile duct syndrome.
Output: itraconazole
With itraconazole, hepatotoxic reactions have only very rarely been reported, and histologic data are lacking.
Output: itraconazole
Thrombotic stroke associated with the use of porcine factor VIII in a patient with acquired haemophilia.
Output: porcine factor VIII
We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII.
Output: pFVIII
We speculate that platelet activation induced by pFVIII may have contributed to thrombosis and suggest that pFVIII be used with caution in elderly patients with pre-existing cardiovascular risk factors.
Output: pFVIII
CONCLUSIONS: Although mirtazapine offers clinicians a combination of strong efficacy and good safety, we suggest bearing SS in mind when prescribing this drug, especially in frail, elderly patients with underlying chronic conditions.
Output: mirtazapine
DISCUSSION: A review of the cases of SS with implication of mirtazapine as the cause was performed.
Output: mirtazapine
Severe serotonin syndrome induced by mirtazapine monotherapy.
Output: mirtazapine
Pulmonary toxicity secondary to procarbazine.
Output: procarbazine
A 64-year-old man presented with proteinuria during postoperative interferon (IFN)-beta therapy against malignant melanoma.
Output: interferon (IFN)-beta
Minimal change nephrotic syndrome developing during postoperative interferon-beta therapy for malignant melanoma.
Output: interferon-beta
To our knowledge this is the first report that demonstrates histological abnormalities of the glomerulus associated with postoperative IFN-beta therapy for the malignant melanoma.
Output: IFN-beta
CONCLUSIONS: Clinicians should be aware of the possible association of thrombocytopenia with lansoprazole and discontinue the drug if thrombocytopenia becomes apparent.
Output: lansoprazole
He was started on oral lansoprazole 60 mg twice daily and, on hospital day 2, his platelet count decreased to 102 x 10(3)/mm(3); on hospital day 3, the platelet count was 36 x 10(3)/mm(3).
Output: lansoprazole
Lansoprazole-induced thrombocytopenia.
Output: Lansoprazole
OBJECTIVE: To describe a case of thrombocytopenia associated with the administration of lansoprazole.
Output: lansoprazole
To date, this is the first reported case of what appears to be isolated thrombocytopenia associated with lansoprazole.
Output: lansoprazole
Life-threatening anaphylactoid reaction to amifostine used with concurrent chemoradiotherapy for nasopharyngeal cancer in a patient with dermatomyositis: a case report with literature review.
Output: amifostine
The patient suffered a life-threatening anaphylactoid reaction to amifostine.
Output: amifostine
Agranulocytosis during clozapine therapy.
Output: clozapine
The female patient received clozapine in a daily dose of 400 mg, which induced agranulocytosis after 2 months.
Output: clozapine
The male patient was treated with 225-mg/day clozapine and the time to the diagnosis of agranulocytosis was 6 weeks.
Output: clozapine
A 53-year-old man developed NMS without rigidity while taking olanzapine.
Output: olanzapine
Atypical neuroleptic malignant syndrome associated with olanzapine.
Output: olanzapine
CASE SUMMARY: We report the case of a 31-year-old patient hospitalized due to behavioral alterations and treated with oral zuclopenthixol, an antipsychotic from the thioxanthene family, who developed an acute, painful erection.
Output: zuclopenthixol
CONCLUSIONS: Priapism is an uncommon but potentially serious adverse effect of zuclopenthixol that practitioners, as with many other antipsychotics, should be aware of.
Output: zuclopenthixol
DISCUSSION: The occurrence of priapism in our patient was related to zuclopenthixol.
Output: zuclopenthixol
OBJECTIVE: To present a single case of zuclopenthixol-induced priapism and a literature review.
Output: zuclopenthixol
Priapism associated with zuclopenthixol.
Output: zuclopenthixol
The capacity of zuclopenthixol to induce priapism is thought to be due to its antagonist activity on alpha-adrenergic receptors.
Output: zuclopenthixol
After identification of the index patient, additional inquiry revealed that the patient's mother was hospitalized previously for overwhelming sepsis associated with metamizole use.
Output: metamizole
Metamizole, a nonsteroidal antiinflammatory agent, is prohibited in the United States because of the risk of agranulocytosis but is widely used in Mexico and other countries.
Output: Metamizole
Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome.
Output: mitomycin
We describe a patient who developed HUS after treatment with mitomycin C (total dose 144 mg/m2) due to a carcinoma of the ascending colon.
Output: mitomycin C
Levofloxacin-induced toxic epidermal necrolysis in an elderly patient.
Output: Levofloxacin
To our knowledge, this case is the first published report of levofloxacin-induced TEN.
Output: levofloxacin
OBJECTIVE: To report a case of cutaneous and hematologic toxicity in a patient treated with IL-2.
Output: IL-2
Subcutaneous IL-2 is safe and well tolerated, with a mortality rate <3%.
Output: IL-2
Toxic epidermal necrolysis associated with interleukin-2.
Output: interleukin-2
A case of anaphylactoid reaction due solely to the use of Gelofusine in a patient with non-haemorrhagic hypovolaemia is presented, with a discussion on the management and the use of allergy identification jewellery.
Output: Gelofusine
Gelofusine allergy--the need for identification jewellery.
Output: Gelofusine
Leiomyosarcoma in urinary bladder after cyclophosphamide therapy for retinoblastoma and review of bladder sarcomas.
Output: cyclophosphamide
To our knowledge, four cases of interstitial pneumonitis associated with fludarabine have been reported in medical literature.
Output: fludarabine
Epoprostenol may be associated rarely with severe erythroderma.
Output: Epoprostenol
Severe erythroderma as a complication of continuous epoprostenol therapy.
Output: epoprostenol
A 50-year-old diabetic and hypertensive male patient is reported who had ticlopidine-induced marrow aplasia partially responsive to colony-stimulating factors and corticosteroids, but experienced complete recovery with cyclosporine.
Output: ticlopidine
There is no consensus on the treatment of ticlopidine-induced marrow aplasia.
Output: ticlopidine
Ticlopidine-induced marrow aplasia treated with cyclosporine.
Output: Ticlopidine
A 53-year-old man developed lower leg edema 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day.
Output: rosiglitazone
A 75-year-old man developed bilateral lower leg edema 6 months after switching from troglitazone to pioglitazone.
Output: pioglitazone
A 77-year-old man developed ankle, hand, and facial swelling 2 weeks after starting rosiglitazone.
Output: rosiglitazone
Two cases of polymorphic ventricular tachycardia induced by the administration of verapamil against paroxysmal supraventricular tachycardia.
Output: verapamil
Verapamil is widely used for the termination of paroxysmal supraventricular tachycardia (PSVT) with little proarrhythmic effect.
Output: Verapamil
We describe two cases of PSVT that changed to non-sustained polymorphic ventricular tachycardia after administration of verapamil.
Output: verapamil
Epsilon-aminocaproic acid and renal complications: case report and review of the literature.
Output: Epsilon-aminocaproic acid
Neonatal mydriasis: intravenous lidocaine adverse reaction.
Output: lidocaine
We present a neonate with a seizure disorder who acutely developed pupillary mydriasis secondary to lidocaine overdose.
Output: lidocaine
We suggest adding this side effect to the list of untoward effects of lidocaine and to the differential diagnosis of fixed dilated pupils in neonates treated with lidocaine.
Output: lidocaine
To the best of our knowledge only two previous cases of AML have been linked to treatment of HCL with purine analogs, both with 2-chlorodeoxyadenosine.
Output: 2-chlorodeoxyadenosine
CONCLUSIONS: Peripheral administration of low-dose vasopressin for septic shock should be discouraged because of the risk of ischemic skin complications.
Output: vasopressin
OBJECTIVE: To describe a case of severe skin necrosis resulting from peripheral intravenous administration of low-dose vasopressin in a patient with catecholamine-resistant septic shock.
Output: vasopressin
Skin necrosis after extravasation of low-dose vasopressin administered for septic shock.
Output: vasopressin
Mitomycin-C induced hemolytic uremic syndrome: a case report.
Output: Mitomycin-C
Mitomycin-C is used widely in the treatment of malignancies and is associated with serious dose related adverse effects including the occurrence of hemolytic uremic syndrome.
Output: Mitomycin-C
Although vasculitis has been reported in the course of hairy cell leukaemia, it has only rarely been reported as the consequence of cladribine treatment.
Output: cladribine
Systemic vasculitis complicating hairy cell leukaemia treatment with cladribine.
Output: cladribine
Gigantomastia induced by bucillamine.
Output: bucillamine
The authors report the first case of bucillamine-induced giant mammary hyperplasia.
Output: bucillamine
The authors describe three families in whom the occurrence of FVS in all the siblings strongly suggests hereditary susceptibility to valproic acid-induced adverse outcome.
Output: valproic acid
Valproate embryopathy in three sets of siblings: further proof of hereditary susceptibility.
Output: Valproate
Generalised pustular psoriasis induced by cyclosporin a withdrawal responding to the tumour necrosis factor alpha inhibitor etanercept.
Output: cyclosporin a
The first case concerns a 70-year-old man who developed severe aplastic anemia 7 weeks after treatment with 500 mg of ticlopidine daily.
Output: ticlopidine
Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases.
Output: Ticlopidine
When the data of the 57 patients are evaluated, a reversible direct cytotoxic effect of ticlopidine on the pluripotent/bipotent hematopoietic progenitor stem cell is proposed.
Output: ticlopidine
Fixed drug eruption to rofecoxib.
Output: rofecoxib
A patient who had been treated with large doses of thyroid hormone for several years developed features of secondary hypothyroidism after thyroid hormone withdrawal.
Output: thyroid hormone
CONCLUSION: There are only a few confirmed cases of gemcitabine-associated HUS despite the widespread use of the drug.
Output: gemcitabine
Gemcitabine-associated hemolytic-uremic syndrome.
Output: Gemcitabine
METHODS: A case is presented of a 45-year-old woman on prolonged gemcitabine treatment for ovarian cancer who developed HUS and recovered after drug discontinuation.
Output: gemcitabine
RESULTS: Including our own patient, a total of 26 cases of gemcitabine-associated HUS were identified.
Output: gemcitabine
An amiodarone optic neuropathy has been described.
Output: amiodarone
Biomicroscopy revealed amiodarone corneal deposits.
Output: amiodarone
Visual changes secondary to initiation of amiodarone: a case report and review involving ocular management in cardiac polypharmacy.
Output: amiodarone
CONCLUSION: Long-term treatment with rifabutin may have a reversible and previously undescribed side-effect on retinal function.
Output: rifabutin
We suggest that objective evaluation of retinal function with electrophysiological methods should be performed in patients with visual disturbance during treatment with rifabutin.
Output: rifabutin
A case is presented of a patient who experienced benzodiazepine withdrawal symptoms on discontinuation of nefazodone, an antidepressant that inhibits the cytochrome P450 3A4 isoenzyme.
Output: nefazodone
A case of SIADH induced by mizoribin administration.
Output: mizoribin
Acute onset of nephrotic syndrome during interferon-alpha retreatment for chronic active hepatitis C.
Output: interferon-alpha
We herein report this rare case of acute onset of nephrotic syndrome during interferon-alpha retreatment.
Output: interferon-alpha
A 21-year-old man with Tourette's syndrome, pedophilia, Asperger's syndrome, and multiple sclerosis experienced seizures after receiving therapy with interferon beta-1a.
Output: interferon beta-1a
Carboplatin hypersensitivity presenting as coronary vasospasm - a case report.
Output: Carboplatin
Capecitabine was discontinued and the allergic reactions resolved after the woman took diphenhydramine for 1 week.
Output: Capecitabine
CONCLUSIONS: The use of fluorouracil treatment with careful monitoring can be considered in a patient with mild allergic reactions to capecitabine.
Output: capecitabine
Fluorouracil for allergic reactions to capecitabine.
Output: capecitabine
It was postulated that the allergic reaction was most likely caused by capecitabine or the intermediate metabolites based on the immediate reappearance of symptoms from the rechallenge, pharmacokinetic data, and well-tolerance of fluorouracil.
Output: capecitabine
OBJECTIVE: To report the safe use of fluorouracil in a patient with breast cancer who had allergic reactions to capecitabine.
Output: capecitabine
After five and six weeks of continuous oral administration of methylprednisolone, the boys developed steroid diabetes.
Output: methylprednisolone
Reduction of methylprednisolone dosage rather than insulin therapy resulted in better control of glycemia.
Output: methylprednisolone
Contrary to previous recommendations, our experience cautions against the further use of high-dose cytarabine in patients who develop PPE, and is a timely reminder of the potential toxicity of this agent, which is now increasingly being used as first-line treatment in the management of haematologic malignancies.
Output: cytarabine
It has been suggested that PPE caused by cytarabine does not recur with subsequent cytarabine re-challenge.
Output: cytarabine
Recurrent palmar-plantar erythrodysaesthesia following high-dose cytarabine treatment for acute lymphoblastic leukemia.
Output: cytarabine
Atypical endometriosis may act as a precancerous lesion in the process of tamoxifen-induced malignant transformation of endometriosis.
Output: tamoxifen
BACKGROUND: Ovarian cancer arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy is rare.
Output: tamoxifen
CONCLUSION: Tamoxifen may cause malignant transformation of endometriosis through atypical endometriosis even in the postmenopausal state.
Output: Tamoxifen
Ovarian endometrioid adenocarcinoma arising from an endometriotic cyst in a postmenopausal woman under tamoxifen therapy for breast cancer: a case report.
Output: tamoxifen
Clinical, spectroscopic, and imaging abnormalities resolved with discontinuation of metronidazole.
Output: metronidazole
Proton MRS examination demonstrated a persistent lactate elevation during metronidazole treatment.
Output: metronidazole
Reversible MR imaging and MR spectroscopy abnormalities in association with metronidazole therapy.
Output: metronidazole
After nine previous uncomplicated cycles she developed severe anaphylaxis to cisplatin.
Output: cisplatin
Anaphylaxis to cisplatin following nine previous uncomplicated cycles.
Output: cisplatin
Anaphylaxis to cisplatin is an infrequent life-threatening complication which may occur even in patients who have received prior treatment with cisplatin.
Output: cisplatin
Although isradipine has been associated with hepatocellular injury, there are no reports of fulminant liver failure with this agent, and our patient had been treated for >2 years without signs of toxicity.
Output: isradipine
CASE SUMMARY: A 58-year-old white woman developed fulminant liver failure while being treated with the macrolide antibiotic clarithromycin for pneumonia.
Output: clarithromycin
CONCLUSIONS: Clarithromycin may be a cause of fulminant liver failure either alone or by inhibiting the metabolism of other drugs.
Output: Clarithromycin
Fulminant liver failure associated with clarithromycin.
Output: clarithromycin
OBJECTIVE: To report a patient developing fulminant liver failure while being treated with clarithromycin for pneumonia.
Output: clarithromycin
A paradoxical ocular effect of brimonidine.
Output: brimonidine
CONCLUSION: Under certain circumstances topical brimonidine can cause paradoxical raised IOP necessitating vigilance in follow-up of patients on topical brimonidine.
Output: brimonidine
PURPOSE: We report an unusual paradoxical effect of brimonidine.
Output: brimonidine
RESULTS: Brimonidine was observed to cause IOP elevation, confirmed on rechallenge, scoring 8 (strong probability) on an adverse drug reaction probability score.
Output: Brimonidine
Gabapentin withdrawal presenting as status epilepticus.
Output: Gabapentin
Visual hallucinations associated with zonisamide.
Output: zonisamide
Doxycycline-induced hypoglycemia in a nondiabetic young man.
Output: Doxycycline
We report the first case of doxycycline-induced hypoglycemia in a young nondiabetic man.
Output: doxycycline
For patients who suffer from osteogenic sarcoma and have anaphylactic reactions to MTX, this desensitization protocol will allow these patients to continue with needed therapeutic or palliative chemotherapy.
Output: MTX
He was later skin tested to confirm allergy to MTX.
Output: MTX
Successful desensitization to high-dose methotrexate after systemic anaphylaxis.
Output: methotrexate
The successful development and implementation of this protocol will have impact on patients who have anaphylactic reactions to MTX but require this medication for specific diseases.
Output: MTX
We present a unique case of GTBM in a patient with myeloma following treatment with Melphalan.
Output: Melphalan
Interstitial pneumonitis associated with sirolimus: a dilemma for lung transplantation.
Output: sirolimus
Hepatotoxicity associated with 6-thioguanine therapy for Crohn's disease.
Output: 6-thioguanine
This case highlights the need to monitor liver enzymes in patients treated with 6-TG and identifies the need for additional research focused on the mechanism of thiopurine-induced hepatic injury.
Output: thiopurine
We describe a case of significant elevation of serum transaminases in a patient treated with 6-TG for a flare of Crohn's disease.
Output: 6-TG
Early peritoneal dialysis has not previously been reported for lisinopril induced multiorgan failure.
Output: lisinopril
Fulminant hepatitis and lymphocyte sensitization due to propylthiouracil.
Output: propylthiouracil
The diagnosis of hypothermia was delayed until it was apparent for several days but resolved with the discontinuation of risperidone and continuation of clozapine.
Output: risperidone
This is a case report of subtle, mild hypothermia in a 54-year old female patient receiving risperidone for schizophrenia.
Output: risperidone
Akathisia is a relatively rare side effect with the newer atypical antipsychotic agents, particularly clozapine, and is easily misdiagnosed in children.
Output: clozapine
Clozapine-induced akathisia in children with schizophrenia.
Output: Clozapine
Two cases of childhood-onset schizophrenia associated with clozapine-induced akathisia responsive to beta-blocker treatment are described.
Output: clozapine
Successful treatment with carbimazole of a hyperthyroid pregnancy with hepatic impairment after propylthiouracil administration: a case report.
Output: propylthiouracil
Minimal change disease in a patient receiving IFN-alpha therapy for chronic hepatitis C virus infection.
Output: IFN-alpha
Emergence of Philadelphia positive chronic myeloid leukaemia during treatment with hydroxyurea for Philadelphia negative essential thrombocythaemia.
Output: hydroxyurea
There are no previous reports in the literature about the emergence of CML during treatment with hydroxyurea.
Output: hydroxyurea
His fever resolved, but he developed symptoms consistent with those of chloroquine toxicity.
Output: chloroquine
OBJECTIVE: To report a case of severe chloroquine toxicity in the presence of high-grade chloroquine-resistant Plasmodium vivax.
Output: chloroquine
Toxicity related to chloroquine treatment of resistant vivax malaria.
Output: chloroquine
Comeoscleral perforation after pterygium excision and intraoperative mitomycin C.
Output: mitomycin C
To the best of our knowledge, corneoscleral melting in the first postoperative week after a single intraoperative application of mitomycin C has not been reported.
Output: mitomycin C
A 71-year-old man, who had a history of a previous bullous drug reaction to a sulfonamide, began receiving an ophthalmic preparation that contained sulfacetamide sodium.
Output: sulfonamide
The patient received only the ophthalmic sulfonamide, and it was used for one day, but he developed Stevens-Johnson syndrome.
Output: sulfonamide
Based on these findings, the patient was diagnosed with diabetes insipidus secondary to lithium therapy and was treated successfully with amiloride.
Output: lithium
Treatment of lithium-induced diabetes insipidus with amiloride.
Output: lithium
We present two cases in which both patients suffered with CLS, which we believe was caused following administration of granulocyte colony-stimulating factor, to our knowledge not described in the intensive care patient previously.
Output: granulocyte colony-stimulating factor
FK506, which began to be administered 12 days earlier, rose to a level of 44 ng/mL (normal range, 10-20 ng/mL) 1 day before neurologic abnormalities began.
Output: FK506
Rapid identification of speech loss linked to FK506 may be important because reduction or cessation of the drug may be associated with reverse of speech loss.
Output: FK506
Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin oedema?
Output: insulin
While 40 mg/day of prednisolone improved hepatic dysfunction dramatically, her diabetic milieu deteriorated seriously.
Output: prednisolone
Intrathecal methotrexate-induced acute cerebellar syndrome.
Output: methotrexate
We describe a patient who developed acute cerebellar syndrome after prophylactic intrathecal methotrexate administration and recovered spontaneously.
Output: methotrexate
Angioimmunoblastic lymphadenopathy with dysproteinemia following doxycycline administration.
Output: doxycycline
Anaphylaxis from isoniazid is a possible side effect to this commonly prescribed antibiotic.
Output: isoniazid
Isoniazid-induced anaphylaxis.
Output: Isoniazid
Carbamazepine-related hyponatremia following cardiopulmonary bypass.
Output: Carbamazepine
We discuss the association between carbamazepine and hyponatremia and the causes of hyponatremia after cardiopulmonary bypass.
Output: carbamazepine
After 5-ASA was discontinued, the polyneuropathy symptoms recovered gradually.
Output: 5-ASA
Sensorimotor polyneuropathy with 5-aminosalicylic acid: a case report.
Output: 5-aminosalicylic acid
This clinical course suggests that the sensorimotor polyneuropathy may have been caused by 5-ASA.
Output: 5-ASA
Disseminated cellulitic cryptococcosis in the setting of prednisone monotherapy for pemphigus vulgaris.
Output: prednisone
Slow acetylator genotypes as a possible risk factor for infectious mononucleosis-like syndrome induced by salazosulfapyridine.
Output: salazosulfapyridine
A lupus-like syndrome associated with infliximab therapy.
Output: infliximab
Infliximab therapy may cause a lupus-like syndrome that is reversible upon discontinuing this agent.
Output: Infliximab
We report in detail an unusual adverse reaction to infliximab therapy, a drug-induced lupus-like clinical syndrome.
Output: infliximab
Despite the underlying hepatitis C, this case represents renal abnormalities consistent with IFNalpha therapy for CML.
Output: IFNalpha
Interferon-alpha-induced focal segmental glomerulosclerosis in chronic myelogenous leukemia: a case report and review of the literature.
Output: Interferon-alpha
The renal biopsy showed focal segmental glomerulosclerosis, which has only been previously reported in two cases of CML treated with IFNalpha.
Output: IFNalpha
Severe autoimmune hemolytic anemia following rituximab therapy in a patient with a lymphoproliferative disorder.
Output: rituximab
We report the first case, to our knowledge, of rituximab-related autoimmune hemolytic anemia.
Output: rituximab
Early-onset acute transverse myelitis following hepatitis B vaccination and respiratory infection: case report.
Output: hepatitis B vaccination
In this paper, we report a case of 3 years-old boy who developed acute onset tetraparesia following a viral respiratory infecction and hepatitis B vaccination.
Output: hepatitis B vaccination
Although it would be expected that, like other type IA toxicities, diphenhydramine-induced cardiotoxicity could be responsive to hypertonic sodium bicarbonate, this finding is largely unappreciated.
Output: diphenhydramine
Diphenhydramine-induced wide complex dysrhythmia responds to treatment with sodium bicarbonate.
Output: Diphenhydramine
However, because diphenhydramine also exhibits type IA sodium channel blockade, cardiac toxicity is also possible.
Output: diphenhydramine
We describe 3 cases of diphenhydramine-induced cardiac toxicity that were responsive to bicarbonate.
Output: diphenhydramine
We describe a patient with extranodal non-Hodgkin lymphoma who developed systemic candidiasis after treatment with a cyclophosphamide-based chemotherapy regimen.
Output: cyclophosphamide
Stevens-Johnson syndrome in a boy with nephrotic syndrome during prednisolone therapy.
Output: prednisolone
We report a case of SJS in a 14-year-old male with nephrotic syndrome, who was treated with oral prednisolone for 6 weeks.
Output: prednisolone
However, in order to avoid neuropathic side effects, patients under thalidomide therapy should be monitored every 6 months with nerve conduction studies while taking the drug.
Output: thalidomide
After a two-month interruption of interferon administration, natural interferon alpha was given but followed by another episode of the same neurological manifestations.
Output: interferon alpha
Multiple sclerosis-like disease secondary to alpha interferon.
Output: alpha interferon
PURPOSE: To describe bilateral optic neuritis that occurred as an adverse effect of recombinant and natural interferon alpha administration.
Output: interferon alpha
We describe a premenopausal woman who, while having tamoxifen due to a diagnosis of in situ ductal carcinoma, developed endometriosis requiring surgery.
Output: tamoxifen
A case report of fatal dapsone-induced agranulocytosis in an Indian mid-borderline leprosy patient.
Output: dapsone
Fatal agranulocytosis in an Indian male receiving 100mg of dapsone daily, hospitalized for mid-borderline leprosy in type I reaction with triple nerve paralysis is reported.
Output: dapsone
Various case reports concerning dapsone-induced agranulocytosis are reviewed.
Output: dapsone
Most cardiac surgical patients have had previous exposure to heparin for diagnostic or therapeutic interventions and hence have an increased susceptibility to developing heparin-induced thrombocytopenia (HIT) postoperatively.
Output: heparin
Acute psychosis associated with levetiracetam.
Output: levetiracetam
A twelve year-old-girl with idiopathic partial epilepsy with secondary generalization, developed acute psychosis 10 days after the administration of levetiracetam.
Output: levetiracetam
The psychotic behavior resolved completely soon after the discontinuation of levetiracetam.
Output: levetiracetam
CASES: "A" was an 8-year-old boy with attention deficit and chronic tic disorder who developed obsessive-compulsive symptoms within 2 weeks of starting risperidone.
Output: risperidone
Obsessive-compulsive symptoms suddenly emerged 10 days after starting risperidone and resolved within 3 days of discontinuation.
Output: risperidone
Risperidone-induced obsessive-compulsive symptoms in two children.
Output: Risperidone
Proliferation of abnormal bone marrow histiocytes, an undesired effect of granulocyte macrophage-colony-stimulating factor therapy in a patient with Hurler's syndrome undergoing bone marrow transplantation.
Output: granulocyte macrophage-colony-stimulating factor
Possible heart failure exacerbation associated with rosiglitazone: case report and literature review.
Output: rosiglitazone
Enoxaparin-induced generalized exanthem.
Output: Enoxaparin
Only one case of a generalized maculopapular rash with enoxaparin has been reported in Europe.
Output: enoxaparin
To our knowledge, this is the first case reported in the English literature of a generalized exanthem due to subcutaneous injection of enoxaparin.
Output: enoxaparin
This report describes an individual with mental retardation who experienced behavioral exacerbation associated with clonazepam prescribed at 2 mg/day (0.02 mg/kg/day) to treat aggression, self-injurious behavior, property destruction, and screaming, which was measured with a 15-minute partial interval recording measurement method.
Output: clonazepam
Cefuroxime-induced immune hemolysis.
Output: Cefuroxime
We report the first case of IHA associated with cefuroxime administration.
Output: cefuroxime
After 39 hours on argatroban, the infusion was stopped when minor bleeding was observed with a concurrent activated partial thromboplastin time (aPTT) of 100 seconds.
Output: argatroban
Argatroban for heparin-induced thrombocytopenia in hepato-renal failure and CVVHD.
Output: heparin
Argatroban is hepatically cleared and may be the preferred direct thrombin inhibitor in the presence of significant renal impairment, but conversely has prolonged effects in hepatic failure.
Output: Argatroban
Schneiderian first-rank symptoms associated with fluvoxamine treatment: a case report.
Output: fluvoxamine
The patient, a 28-year-old man suffering from panic disorder, developed several first-rank symptoms during fluvoxamine administration.
Output: fluvoxamine
This communication describes a patient who developed Schneiderian first-rank symptoms in the course of treatment with fluvoxamine.
Output: fluvoxamine
This finding suggests that fluvoxamine can precipitate Schneiderian first-rank symptoms in some susceptible patients.
Output: fluvoxamine
We present a surprising case of a woman schizophrenic patient treated with clozapine suffering from EPS.
Output: clozapine
Hyperpigmentation during interferon-alpha therapy for chronic hepatitis C virus infection.
Output: interferon-alpha
Anaphylaxis after the injection of chymopapain occurs in about 1% of such cases.
Output: chymopapain
Both patients suddenly became hypotensive after injection of chymopapain into a disk.
Output: chymopapain
The newborn manifested a four day course of lethargy with unexplained high lithium levels in the adult toxic range.
Output: lithium
Carbamazepine-induced systemic lupus erythematosus-like disease.
Output: Carbamazepine
The cases of CBZ-induced SLE reported in the literature were reviewed.
Output: CBZ
After four months, while receiving RH, he developed painful bilateral gynaecomastia.
Output: RH
Gynaecomastia is a rarely reported adverse drug reaction due to isoniazid therapy.
Output: isoniazid
Isoniazid associated, painful, bilateral gynaecomastia.
Output: Isoniazid
Heparin-associated thrombocytopenia: successful therapy with the heparinoid Org 10172 in a patient showing cross-reaction to LMW heparins.
Output: Heparin
Hemodynamic collapse following labetalol administration in preeclampsia.
Output: labetalol
Pleuropulmonary changes during treatment of Parkinson's disease with a long-acting ergot derivative, cabergoline.
Output: cabergoline
Flaccid quadriparesis was noted after discontinuation of vecuronium.
Output: vecuronium
This entity is probably related to a combination of high doses of corticosteroids, vecuronium administration and metabolic abnormalities associated with respiratory failure.
Output: vecuronium
Reversible sclerotic changes of lumbar spine and femur due to long-term oral isotretinoin therapy.
Output: isotretinoin
Although an association between exposure to bleomycin and the development of scleroderma has been suspected, few cases are reported.
Output: bleomycin
Our series of 3 patients supports a causal connection between bleomycin and scleroderma.
Output: bleomycin
Scleroderma in association with the use of bleomycin: a report of 3 cases.
Output: bleomycin
We describe the development of cutaneous scleroderma in 3 patients coincident with the use of bleomycin in low cumulative doses of less than 100 U.
Output: bleomycin
A patient presented with dilated cardiomyopathy after many years of overusing an adrenaline inhaler.
Output: adrenaline
Dilated cardiomyopathy associated with chronic overuse of an adrenaline inhaler.
Output: adrenaline
Carbamazepine-induced systemic lupus erythematosus.
Output: Carbamazepine
SLE receded after withdrawal of carbamazepine and treatment with anti-inflammatory drugs.
Output: carbamazepine
We report a case of acne fulminans occurring during treatment with 13-cis-retinoic acid for cystic acne.
Output: 13-cis-retinoic acid
Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma.
Output: valproic acid
Valproic acid induced coma is presented in an adult patient without a history of metabolic disease.
Output: Valproic acid
Asterixis induced by carbamazepine therapy.
Output: carbamazepine
Hemorrhagic cystitis is a significant toxic effect of cyclophosphamide therapy.
Output: cyclophosphamide
This case report describes a 38-year-old male in whom SIADH was strongly suspected secondary to Tegretol therapy to control a seizure disorder.
Output: Tegretol
Gestational diabetes was no less severe (degree of hyperglycaemia, need for insulin therapy) when associated with norethisterone.
Output: norethisterone
In a single practice during the 21 years 1971-1991, the incidence of gestational diabetes in pregnancies in which norethisterone was prescribed was 32.4% (22 of 69) in comparison with 7.1% in pregnancies in which the women did not take norethisterone (137 of 1,684) (p < 0.001).
Output: norethisterone
Norethisterone in these 69 pregnancies accounted for 33.3% (5 of 15) cases of clitoral hypertrophy diagnosed in 100,756 consecutive births.
Output: Norethisterone
An adverse reaction to IFN was strongly suspected as the cause of CHF.
Output: IFN
Multiple myeloma complicated by congestive heart failure following first administration of recombinant alpha-interferon.
Output: recombinant alpha-interferon
Neutrophilic eccrine hidradenitis mimicking cutaneous vasculitis in a lupus patient: a complication of cyclophosphamide.
Output: cyclophosphamide
We report a case of NEH masquerading as cutaneous vasculitis in a woman receiving cyclophosphamide for lupus nephritis.
Output: cyclophosphamide
Generalised cutaneous rash associated with ganciclovir therapy has rarely been reported in literature.
Output: ganciclovir
Renal tubular acidosis secondary to FK506 in living donor liver transplantation: a case report.
Output: FK506
Surgeons and physicians should therefore be aware of the potential for RTA to occur with FK506 after any organ transplantation.
Output: FK506
The mechanism of RTA induced by FK506 has not yet been clearly elucidated.
Output: FK506
The treatment for acidosis and hyperkalaemia should be started as soon as RTA is diagnosed, and the dosage of FK506 should also be reduced if possible.
Output: FK506
We report a case of RTA secondary to FK506 administration in liver transplantation.
Output: FK506
A 74-year-old patient with idiopathic Parkinson's disease was evaluated for unintended sleep episodes that occurred after long-term treatment with 400 mg/day of L-dopa.
Output: L-dopa
L-DOPA-induced excessive daytime sleepiness in PD: a placebo-controlled case with MSLT assessment.
Output: L-DOPA
The authors' results suggest that L-dopa may cause daytime somnolence in some patients with Parkinson's disease.
Output: L-dopa
Neurotoxicity of intrathecal methotrexate: MR imaging findings.
Output: methotrexate
We attribute the clinical and radiographic findings to cytotoxic edema secondary to intrathecal methotrexate.
Output: methotrexate
We present a case of a 20-year-old woman who ingested 900 mg of glyburide causing refractory hypoglycemia resistant to treatment with intravenous dextrose, glucagon, and diazoxide.
Output: glyburide
Ocular ethambutol toxicity.
Output: ethambutol
The most commonly recognized toxic effect of ethambutol is optic neuropathy, which generally is considered uncommon and reversible in medical literature.
Output: ethambutol
We describe a 43-year-old man who developed signs and symptoms of bilateral optic neuropathy during treatment with ethambutol.
Output: ethambutol
Early overanticoagulation with acenocoumarol due to a genetic polymorphism of cytochrome P450 CYP2C9.
Output: acenocoumarol
We report the case of a young healthy woman who presented an early overanticoagulation when receiving acenocoumarol for a first thromboembolic episode.
Output: acenocoumarol
Colchicine-induced myopathy in a teenager with familial Mediterranean fever.
Output: Colchicine
CONCLUSIONS: Colchicine-induced myopathy should be excluded in patients with FMF who present with generalized muscle weakness.
Output: Colchicine
DISCUSSION: Colchicine, the most important drug in treatment of FMF, can cause myopathy in patients with impaired renal and hepatic function.
Output: Colchicine
In our patient, an objective causality scale showed that therapeutic doses of colchicine for FMF were the definite cause of myopathy, even though his renal and hepatic function were normal.
Output: colchicine
OBJECTIVE: To report a case of colchicine-induced myopathy in a teenager with familial Mediterranean fever (FMF).
Output: colchicine
Infectious toxicity of dexamethasone during all remission-induction chemotherapy: report of two cases and literature review.
Output: dexamethasone
A diagnosis of infliximab-induced lupus was made and the drug treatment was withdrawn.
Output: infliximab
Infliximab-induced lupus in Crohn's disease: a case report.
Output: Infliximab
This is the first case, to our knowledge, of onset of prolonged infliximab-induced lupus.
Output: infliximab
Severe Raynaud's phenomenon with yohimbine therapy for erectile dysfunction.
Output: yohimbine
We describe a patient with CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangiectasia) who paradoxically experienced worsening of Raynaud's phenomenon when using yohimbine for ED.
Output: yohimbine
After initiation of topical vitamin D3 ointment (20 micro g/g of tacalcitol) 10 g/day for the skin lesions, both the serum level of calcium and urinary excretion of calcium increased gradually.
Output: vitamin D3
2-Chloro-deoxyadenosine induces durable complete remission in Castleman's disease but may accelerate its transformation to non-Hodgkin's lymphoma.
Output: 2-Chloro-deoxyadenosine