niryuu/sni-each-converted huggingface dataset:
Therefore, it is reasonable to conclude that: 1) 2-CdA can induce durable complete remission in MCD patients but unfortunately it cannot cure the disease; 2) the possibility that 2-CdA may accelerate the transformation of MCD to NHL cannot be ruled out.
Output: 2-CdA
All patients had taken phenytoin for variable time periods (range 16-80 days; mean: 40) and were on the medication when the skin lesions first appeared.
Output: phenytoin
Erythema multiforme associated with phenytoin and cranial radiation therapy: a report of three patients and review of the literature.
Output: phenytoin
Reflex sympathetic dystrophy syndrome in renal transplanted patients under immunosuppression with tacrolimus.
Output: tacrolimus
We now present four cases of RSDS in kidney transplant recipients treated with tacrolimus.
Output: tacrolimus
METHODS: In an institutional practice setting, two women, aged 25 and 45, developed acute myopia after starting topiramate for epilepsy.
Output: topiramate
Doxycycline-induced photo-onycholysis.
Output: Doxycycline
We present a case of photo-onycholysis in a patient treated with doxycycline for acne vulgaris.
Output: doxycycline
A new type of minocycline-induced cutaneous hyperpigmentation.
Output: minocycline
Pigmentary disorders are recognized adverse effects of the semi-synthetic tetracycline derivative antibiotic, minocycline.
Output: minocycline
This fourth type of cutaneous minocycline hyperpigmentation may be a variant of Type I, but based on clinical, pathological and microanalytical differences, appears to be a new entity.
Output: minocycline
Three distinct types of minocycline-induced cutaneous pigmentation have been described.
Output: minocycline
We report two patients with acne vulgaris with a fourth type of minocycline-induced cutaneous pigmentation.
Output: minocycline
Ciprofloxacin-induced toxic epidermal necrolysis in a patient with systemic lupus erythematosus.
Output: Ciprofloxacin
We report here a case of TEN after administration of ciprofloxacin.
Output: ciprofloxacin
A 56-year-old Caucasian man who received concomitant chemotherapy and radiation for head and neck cancer developed fever concurrent with the administration of amifostine.
Output: amifostine
Amifostine-induced fever: case report and review of the literature.
Output: Amifostine
To our knowledge, this is the first case report that demonstrates the occurrence of fever with low-dose amifostine therapy without the manifestation of accompanying rash or hypotension.
Output: amifostine
Acute interstitial nephritis due to pantoprazole.
Output: pantoprazole
After 5 weeks of therapy, she stopped taking pantoprazole due to general malaise.
Output: pantoprazole
OBJECTIVE: To describe what is believed, as of November 4, 2003, to be the first case published in the literature of acute interstitial nephritis (AIN) due to pantoprazole.
Output: pantoprazole
The Naranjo probability scale suggests a highly probable relationship between AIN and pantoprazole therapy in this patient.
Output: pantoprazole
There have been several reported cases of omeprazole-induced AIN.
Output: omeprazole
Propecia-associated bilateral cataract.
Output: Propecia
To the best of the authors' knowledge, this is the first reported case of Propecia-associated cataract.
Output: Propecia
Scleromyxedema in a patient with multiple sclerosis and monoclonal gammopathy on interferon beta-1a.
Output: interferon beta-1a
CASE SUMMARY: Two children with attention deficit disorder treated with methylphenidate as a simple drug developed fixed drug eruption of the scrotum.
Output: methylphenidate
CONCLUSIONS: Fixed drug rash induced by methylphenidate is a possible but rare phenomenon.
Output: methylphenidate
Fixed drug eruption of the scrotum due to methylphenidate.
Output: methylphenidate
OBJECTIVE: To report two cases of fixed drug eruption induced by methylphenidate.
Output: methylphenidate
Methotrexate pneumonitis in nonsurgical treatment of ectopic pregnancy.
Output: Methotrexate
We describe a case of pneumonitis following local administration of methotrexate for nonsurgical termination of an ectopic pregnancy.
Output: methotrexate
BACKGROUND: The risk/benefit ratio of warfarin therapy changes in the over 75s, when haemorrhagic side-effects become more common.
Output: warfarin
CASE REPORT: A woman of 80 years, on long-term warfarin therapy presented with an acute dissecting thoracic aortic aneurysm; on investigation the only precipitating factor found was an international normalised ratio of 4.8.
Output: warfarin
Warfarin-associated thoracic aortic dissection in an elderly woman.
Output: Warfarin
Cutaneous vasculitis secondary to ramipril.
Output: ramipril
Here we report ramipril-induced cutaneous vasculitis in a patient who required steroid therapy to control it.
Output: ramipril
Ramipril-induced cutaneous vasculitis is particularly rare and our case was atypical because the patient had tolerated lisinopril before.
Output: Ramipril
CONCLUSION: This is, to our knowledge, the first report of severe myelopathy following accidental intrathecal administration of doxorubicin.
Output: doxorubicin
Neurological improvement and rehabilitation potential following toxic myelopathy due to intrathecal injection of doxorubicin.
Output: doxorubicin
RESULTS: Evidence of neurological improvement and rehabilitation potential after severe myelopathy due to intrathecal injection of doxorubicin.
Output: doxorubicin
STUDY DESIGN: Case report of a 31-year-old woman who presented with toxic myelopathy due to intrathecal administration of doxorubicin.
Output: doxorubicin
Thus, clinical recognition of sleep disordered breathing should be taken into account when rheumatoid arthritis patients are to be treated with infliximab.
Output: infliximab
We describe two ELBW infants affected by hyperkalaemia, treated with Kayexalate, who developed serious hypernatraemia, that has never been reported before in preterm infants.
Output: Kayexalate
Bull's-eye maculopathy associated with quinacrine therapy for malaria.
Output: quinacrine
RESULTS: A patient developed a bilaterally symmetric bull's-eye maculopathy 45 years after taking quinacrine for 18 months as prophylaxis against malaria.
Output: quinacrine
Cerebral infarcts in a pediatric patient secondary to phenylpropanolamine, a recalled medication.
Output: phenylpropanolamine
We present a case of stroke after PPA ingestion that occurred 4 months after the recall in an 8-year-old boy on chronic peritoneal dialysis.
Output: PPA
Ciprofloxacin-induced psychosis.
Output: Ciprofloxacin
DATA SYNTHESIS: A 49-year-old man developed symptoms of severe psychosis concomitant with ciprofloxacin (250 mg bid) treatment.
Output: ciprofloxacin
OBJECTIVE: To report a case of ciprofloxacin-induced psychosis and to discuss occurrence rates, risk factors, possible etiologies, preventive measures, and treatment courses for this adverse reaction.
Output: ciprofloxacin
Agranulocytosis induced by vancomycin in an ESRD patient on CAPD.
Output: vancomycin
Agranulocytosis is a rare adverse effect associated with prolonged vancomycin therapy, and is potentially serious, especially in end stage renal disease (ESRD) patients.
Output: vancomycin
We describe a continuous ambulatory peritoneal dialysis (CAPD) patient that developed vancomycin-induced agranulocytosis during treatment for methicillin-resistant Staphylococcus aureus (MRSA)-associated external cuff infection and pneumonia.
Output: vancomycin
It is very likely that the dexamethasone used in the antiemetic drug regimen contributed to the development of osteonecrosis in these patients.
Output: dexamethasone
Osteonecrosis is a serious side effect of antiemetic treatment with dexamethasone and this serious complication should be incorporated in the current guidelines.
Output: dexamethasone
Patients should be informed about the risk of osteonecrosis when taking dexamethasone as an antiemetic drug.
Output: dexamethasone
Development of Peyronie's disease during long-term colchicine treatment.
Output: colchicine
However here we reported two patients, presenting with PD during high dose colchicine treatment for familiar mediterranean fever (FMF).
Output: colchicine
A patient developed cholestatic hepatitis while being treated with nitrofurantoin.
Output: nitrofurantoin
A case of phenobarbital exacerbation of a preexisting maladaptive behavior partially suppressed by chlorpromazine and misinterpreted as chlorpromazine efficacy.
Output: phenobarbital
Ten years of behavioral data are presented to support the hypothesis that phenobarbital was exacerbating maladaptive behaviors.
Output: phenobarbital
Pilocarpine toxicity and the treatment of xerostomia.
Output: Pilocarpine
Anticonvulsant hypersensitivity syndrome associated with Bellamine S, a therapy for menopausal symptoms.
Output: Bellamine S
A case of heatstroke is reported in a 32-year-old man diagnosed with schizophrenia and on clozapine monotherapy.
Output: clozapine
Heat stroke in schizophrenia during clozapine treatment: rapid recognition and management.
Output: clozapine
Gemcitabine-related radiation recall preferentially involves internal tissue and organs.
Output: Gemcitabine
The literature search found 12 cases of radiation recall caused by gemcitabine.
Output: gemcitabine
The majority of radiation recall reactions attributed to gemcitabine are reported to affect internal tissue or organs.
Output: gemcitabine
An immediate hemolytic reaction induced by repeated administration of oxaliplatin.
Output: oxaliplatin
CASE REPORT: We report a patient who developed a DAT-positive hemolytic episode after a red cell (RBC) transfusion was delivered during the infusion of her 17th cycle of oxaliplatin.
Output: oxaliplatin
Clinicians should be aware of the signs and symptoms of neurotoxicity during treatment, as well as predisposing factors that put patients receiving methotrexate at risk for neurotoxic effects.
Output: methotrexate
Fatal acute encephalomyelitis after a single dose of intrathecal methotrexate.
Output: methotrexate
We report a third case of a 6-week-old infant with Escherichia coli sepsis who received ampicillin and other antibiotics and subsequently developed TEN.
Output: ampicillin
One patient developed large intramural esophageal hematoma as a complication of heparin therapy.
Output: heparin
Eosinophilic cystitis after bladder instillation with dimethyl sulfoxide.
Output: dimethyl sulfoxide
Acute dystonia during pegylated interferon alpha therapy in a case with chronic hepatitis B infection.
Output: pegylated interferon alpha
In this case report, we present clinical and laboratory findings of a case with chronic hepatitis B that developed acute dystonia soon after the first dose of pegylated interferon alpha.
Output: pegylated interferon alpha
Restless legs syndrome due to interferon-alpha.
Output: interferon-alpha
Restless legs syndrome may thus be an adverse effect of IFN alpha treatment.
Output: IFN alpha
We describe a heroin abuser in whom clinical and laboratory manifestations of acute hepatitis B and C appeared a few days after the insertion of a subcutaneous naltrexone implant.
Output: naltrexone
Sweet's syndrome associated with sargramostim (granulocyte-macrophage colony stimulating factor) treatment.
Output: sargramostim
We report a case of Sweet's syndrome in association with sargramostim treatment following chemotherapy for acute myelogenous leukemia.
Output: sargramostim
The autopsy findings and a detailed medical history supported the conclusion that clozapine-induced hypersensitivity myocarditis was the most likely cause of death.
Output: clozapine
The case concerns the sudden death of a 29-year-old male during clozapine therapy started 2 weeks before.
Output: clozapine
Our patient was a 72-year-old man with advanced Parkinson's disease (PD) who received levodopa and anti-cholinergic drugs and whose head had become almost completely bald.
Output: levodopa
A patient with monocular open-angle glaucoma had trichiasis, a condition associated with the use of a prostaglandin analog.
Output: prostaglandin
Trichiasis associated with prostaglandin analog use.
Output: prostaglandin
Fatal pulmonary fibrosis associated with BCNU: the relative role of platelet-derived growth factor-B, insulin-like growth factor I, transforming growth factor-beta1 and cyclooxygenase-2.
Output: BCNU
These novel findings may offer specific therapeutic targets in the treatment of BCNU-associated pulmonary fibrosis.
Output: BCNU
We further used immunohistochemistry (IHC) to examine the relative role of platelet-derived growth factor-B (PDGF-B), insulin-like growth factor I (IGF-I), transforming growth factor-beta1 (TGF-beta1) and cyclooxygenase-2 (COX-2) in the pathogenesis of BCNU-related pulmonary fibrosis.
Output: BCNU
We report here a 26-year-old female with diffuse large B-cell lymphoma who died of severe pulmonary fibrosis 81 days after the administration of high-dose BCNU (600 mg/m2).
Output: BCNU
Dorzolamide-induced choroidal detachment in a surgically untreated eye.
Output: Dorzolamide
METHODS: A 76-year-old woman with primary open-angle glaucoma and no history of ocular surgery developed a choroidal detachment 12 hours after initiation of therapy with dorzolamide eye drops.
Output: dorzolamide
We document the abrupt development of an extensive choroidal detachment after initiation of dorzolamide therapy in a surgically untreated eye with primary open-angle glaucoma.
Output: dorzolamide
Deepening of lid sulcus from topical bimatoprost therapy.
Output: bimatoprost
Lichen planus induced by hepatitis B vaccination: a new case and review of the literature.
Output: hepatitis B vaccination
Case report: life-threatening hypoglycaemia associated with sulfadoxine-pyrimethamine, a commonly used antimalarial drug.
Output: sulfadoxine-pyrimethamine
Initial treatment with heparin was substituted with thrombolysis, which resulted in clinical improvement and dissolution of right heart thrombus but was followed by fatal intracerebral haemorrhage.
Output: heparin
Extensive forearm deep venous thrombosis following a severe infliximab infusion reaction.
Output: infliximab
After 3- to 13-month period of therapy without indapamide, glucose levels of all patients decreased and diabetes disappeared.
Output: indapamide
After stopping indapamide, glucose tolerance impairing may be reversed.
Output: indapamide
CONCLUSION: Therapy with indapamide may induce diabetes in essential hypertension patients.
Output: indapamide
Possible induction of diabetes by treatment of hypertension with indapamide (with four case reports).
Output: indapamide
CONTEXT: Previous investigators have reported discrepancies between hematologic, marrow morphologic, and cytogenetic responses to imatinib mesylate among patients with chronic myeloid leukemia (CML).
Output: imatinib mesylate
Despite a hematologic response in all 3 patients, none of them achieved cytogenetic remission, and all progressed to blast crisis at 7 to 10 months of imatinib therapy.
Output: imatinib
In addition to disease refractoriness, rare instances of disease progression from chronic phase to blast crisis during imatinib therapy have recently been anecdotally reported.
Output: imatinib
OBJECTIVES: To describe the clinicopathologic features of 3 patients with CML who rapidly progressed from chronic phase to blast crisis while taking imatinib and to perform a review of the literature.
Output: imatinib
Our findings suggest that significant progression of marrow reticulin fibrosis during imatinib therapy can be an indicator for a return or progression of CML and, in some patients with CML, imatinib may promote cytogenetic clonal evolution, resulting in a poor response to treatment.
Output: imatinib
Progression of chronic myeloid leukemia to blast crisis during treatment with imatinib mesylate.
Output: imatinib mesylate
L-asparaginase-induced severe necrotizing pancreatitis successfully treated with percutaneous drainage.
Output: L-asparaginase
Most cases of pancreatitis associated with L-asparaginase toxicity are self-limiting and respond favorably to nasogastric decompression and intravenous hyperalimentation.
Output: L-asparaginase
Pancreatitis has been noted to be a complication in 2-16% of patients undergoing treatment with L-asparaginase for a variety of pediatric neoplasms.
Output: L-asparaginase
We present a pediatric patient with leukemia and a severe, L-asparaginase-induced necrotizing pancreatitis, treated successfully with percutaneous drainage used to flush the infected necrotic parts.
Output: L-asparaginase
Disulfiram-induced fulminant hepatic failure in an active duty soldier.
Output: Disulfiram
Fulminant hepatic failure is a rare complication of disulfiram treatment for alcoholism.
Output: disulfiram
This case describes fulminant hepatic failure in a patient taking disulfiram with no previous liver disease and report of being compliant with alcohol abstinence.
Output: disulfiram
Tiagabine overdose causes an unusual array of neurological symptoms, many similar to reported adverse effects during therapeutic use.
Output: Tiagabine
A case of sideroblastic anemia is presented in a patient with a left ventricular assist device drive-line infection who was receiving linezolid, an antibiotic used for serious infections with gram-positive organisms.
Output: linezolid
As linezolid has been shown to have hematologic side effects, blood count monitoring is recommended in patients receiving this drug for long-term therapy.
Output: linezolid
Sideroblastic anemia due to linezolid in a patient with a left ventricular assist device.
Output: linezolid
In this report, two newborns with congenital heart anomalies demonstrated the harlequin color change, one whose skin findings showed a course related to the dose of systemic prostaglandin E1, suggesting a possible association.
Output: prostaglandin E1
The harlequin color change and association with prostaglandin E1.
Output: prostaglandin E1
Acute renal insufficiency is known to occur in patients who are taking ciprofloxacin, particularly the elderly.
Output: ciprofloxacin
Ciprofloxacin-induced renal insufficiency in cystic fibrosis.
Output: Ciprofloxacin
Multiple mechanisms for ciprofloxacin-induced nephrotoxicity have been proposed.
Output: ciprofloxacin
We report two young patients with cystic fibrosis who presented with acute renal insufficiency after 2-3 weeks of oral ciprofloxacin therapy.
Output: ciprofloxacin
An objective causality assessment indicated a probable relationship between clotting abnormality and warfarin administration, although the degree of elevation of the INR was unusual in the light of the daily warfarin dose and duration of its exposure.
Output: warfarin
Based on the clinical status of the patient, it was suspected that several conditions contributed to the abnormal hypersensitivity to warfarin.
Output: warfarin
Despite the low dosage of warfarin, international normalized ratio (INR) was markedly elevated from 1.15 to 11.28 for only 4 days, and bleeding symptoms concurrently developed.
Output: warfarin
In view of our experience in the present case, it should be stressed that close monitoring of coagulation capacity is necessary in critically ill patients in order to avoid fatal haemorrhage after initiating warfarin therapy regardless of the dosage.
Output: warfarin
Unusual hypersensitivity to warfarin in a critically ill patient.
Output: warfarin
During analysis of 28 patients receiving CAP with concomitant radiation (XRT) for pancreatic cancer (resected or locally advanced), two patients developed signs and symptoms consistent with peripheral neuropathy.
Output: CAP
Knowledge regarding potential adverse effects of CAP is paramount and dose modification is indicated with development of neurotoxicity.
Output: CAP
Patient B developed perioral and upper extremity paresthesias during the fourth cycle of CAP alone (2500 mg/m2).
Output: CAP
Peripheral neuropathy associated with capecitabine.
Output: capecitabine
We conclude peripheral neuropathy with 5-FU is rare.
Output: 5-FU
Severe hypo-alpha-lipoproteinemia during treatment with rosiglitazone.
Output: rosiglitazone
We report three patients, all of whom had preexisting diabetic dyslipidemia, who showed a profound reduction in plasma HDL cholesterol and apolipoprotein AI levels soon after the initiation of rosiglitazone therapy.
Output: rosiglitazone
In all cases, drugs in addition to quetiapine were detected, but in cases #1 and #2, the cause of death was considered to be a quetiapine overdose and the other drugs were not considered to be contributory.
Output: quetiapine
These cases were chosen for study because they were all deaths as a result of suicidal ingestion of drugs in which quetiapine was considered a significant factor.
Output: quetiapine
We present three cases from the Provincial Toxicology Center of British Columbia, Canada in which suicidal overdose deaths were associated with quetiapine.
Output: quetiapine
After approximately two weeks of sertraline treatment he noted an intense itching sensation in his scalp after eating a piece of chocolate cake.
Output: sertraline
Pulmonary lymphohistiocytic reactions temporally related to etanercept therapy.
Output: etanercept
This report details the pulmonary pathologic findings in four patients with rheumatoid arthritis, who developed new onset of pulmonary signs and symptoms with alveolar infiltrates temporally related to the institution of etanercept therapy.
Output: etanercept
Paradoxical cerebral cortical hyperexcitability following flupirtine overdose.
Output: flupirtine
We report the case of a patient with increased cerebral cortical excitability following intoxication with flupirtine, a centrally acting analgesic and antispastic drug.
Output: flupirtine
We present two cases of anaphylaxis under anaesthesia where return of spontaneous circulation was refractory to epinephrine, but occurred following the administration of the alpha-agonist metaraminol.
Output: metaraminol
In a postoperative patient with pre-existent myasthenia gravis, oral verapamil caused a marked exacerbation in myasthenic weakness.
Output: verapamil
Vogt-Koyanagi-Harada disease occurring during interferon alpha therapy for chronic hepatitis C.
Output: interferon alpha
After an extensive review of the literature, we believe that this is the first communication of the successful use of amiodarone to control hyperthyroidism in a patient with PTU-induced fulminant hepatitis.
Output: PTU
Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure.
Output: propylthiouracil
We present a 20-year-old woman with Basedow-Graves' disease who developed PTU-induced fulminant hepatitis, which progressed to acute hepatic failure with grade III hepatic encephalopathy.
Output: PTU
OBSERVATIONS: We observed aggravation and spreading of a psoriatic plaque when treated topically with the toll-like receptor (TLR) 7 agonist imiquimod.
Output: imiquimod
Psoriasis triggered by toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors.
Output: imiquimod
Since imiquimod induces large amounts of type I interferon production from TLR7-expressing plasmacytoid dendritic cell precursors (PDCs), the natural interferon-producing cells of the peripheral blood, we asked whether PDCs are present in psoriatic skin.
Output: imiquimod
The exacerbation of psoriasis was accompanied by a massive induction of lesional type I interferon activity, detected by MxA expression after imiquimod therapy.
Output: imiquimod
Vision declined after treatment with methylprednisolone, after which fundus examination became consistent with progressive outer retinal necrosis.
Output: methylprednisolone
DLST is a good diagnostic tool for AZA allergy, especially for severe drug allergy cases.
Output: AZA
Drug eruption caused by azathioprine: value of using the drug-induced lymphocytes stimulation test for diagnosis.
Output: azathioprine
We report AZA-induced drug eruption that developed in two cases of systemic scleroderma with polymyositis.
Output: AZA
Tardive dyskinesia in 2 patients treated with ziprasidone.
Output: ziprasidone
Two of our patients developed TD after 23 months and 34 months of ziprasidone monotherapy, respectively.
Output: ziprasidone
Asthenozoospermia: possible association with long-term exposure to an anti-epileptic drug of carbamazepine.
Output: carbamazepine
The patient was found to have no motile sperm with a normal sperm count, while taking a dose of 400 mg/day of carbamazepine.
Output: carbamazepine
Scrotal ulceration induced by all-trans retinoic acid in a patient with acute promyelocytic leukemia.
Output: retinoic acid
The ulcer did not respond to antibiotic treatment and healed shortly after withholding ATRA.
Output: ATRA
We report the development of scrotal ulcer in a patient with acute promyleocytic leukemia (APL) within 10 days of treatment with ATRA at a dose of 40 mg orally twice daily.
Output: ATRA
A case of clozapine-induced tonic-clonic seizures managed with valproate: implications for clinical care.
Output: clozapine
Following discontinuation of clozapine, she was rechallenged and again was observed to have seizures.
Output: clozapine
These findings suggest that clozapine-induced seizures can be successfully treated, that gradual dose titration can reduce the likelihood of further episodes of seizures and that concomitant use of a suitable mood stabilizer/anti-epileptic medication can improve the outcome of treatment-resistant schizophrenia.
Output: clozapine
We describe a case of clozapine-induced seizures in a patient with treatment-resistant schizophrenia.
Output: clozapine
CONCLUSIONS: Symptoms and pathologic changes of colitis are associated with exposure to rofecoxib.
Output: rofecoxib
OBJECTIVES: To describe clinical and pathologic findings in patients noted to develop lower gastrointestinal symptoms when exposed to rofecoxib.
Output: rofecoxib
To the best of our knowledge, this is the first reported patient with captopril-induced pemphigus in whom no new lesions developed after subsequent treatment with enalapril.
Output: captopril
We report a case of drug-induced pemphigus caused by an angiotensin-converting enzyme inhibitor, captopril.
Output: captopril
Neuropathy is a significant side effect of thalidomide therapy, which may limit its clinical use.
Output: thalidomide
Thalidomide neuropathy in childhood.
Output: Thalidomide
Thalidomide was withdrawn from world markets in 1961 following recognition of its teratogenic effects.
Output: Thalidomide
We report four cases of sensorimotor axonal neuropathy in children aged 10-15 years, treated with thalidomide for myxopapillary ependymoma, Crohn's disease and recurrent giant aphthous ulceration.
Output: thalidomide
Cerebral edema associated with Gliadel wafers: two case studies.
Output: Gliadel
Following are two clinical case reports demonstrating profound cerebral edema associated with implantation of Gliadel wafers.
Output: Gliadel
It is likely that RA contributed to the deterioration in renal function in these patients.
Output: RA
Retinoic acid may increase the risk of bone marrow transplant nephropathy.
Output: Retinoic acid
The occurrence of BMTN in two children treated with RA in our unit is unlikely to be coincidental.
Output: RA
He developed a late secondary infection in some sites treated with imiquimod.
Output: imiquimod
A 64-year-old man with schizophrenia developed myoclonic jerks when given higher doses of quetiapine.
Output: quetiapine
Quetiapine-induced myoclonus.
Output: Quetiapine
We report a case of myoclonus induced by quetiapine.
Output: quetiapine
Treatment-related myelodysplastic syndrome after temozolomide for recurrent high-grade glioma.
Output: temozolomide
Typically, drug-induced neutropenia occurs in a patient receiving a semisynthetic penicillin for two weeks or more.
Output: penicillin
Livedo reticularis associated with interferon alpha therapy in two melanoma patients.
Output: interferon alpha
These cases highlight the occurrence of livedo reticularis as an uncommon side-effect of interferon alpha treatment.
Output: interferon alpha
We report two patients who developed intense livedo reticularis clearly related to the administration of interferon alpha 2b as an adjuvant therapy for melanoma.
Output: interferon alpha 2b
Anti-tuberculous drugs had been stopped on the 2nd day of therapy due to development of optic neuritis secondary to ethambutol administration at another hospital.
Output: ethambutol
During the anti-tuberculous therapy, visual loss can be related to ethambutol toxicity or the tuberculosis infection itself.
Output: ethambutol
In addition, ethambutol rarely causes visual loss during the early period or when given at lower doses.
Output: ethambutol
It is well-recognized that flucloxacillin may occasionally result in fatal hepatic injury.
Output: flucloxacillin
Zoledronic acid-induced severe hypocalcaemia in a prostate cancer patient with extensive osteoblastic bone metastases.
Output: Zoledronic acid
Mucosal pigmentation after oral lichen planus treatment with topical tacrolimus.
Output: tacrolimus
We report the first histopathologically documented case of oral mucosa pigmentation after OLP treatment with topical tacrolimus.
Output: tacrolimus
Risperidone withdrawal-related respiratory dyskinesia: a case diagnosed by spirography and fibroscopy.
Output: Risperidone
Therefore, clinicians should pay close attention to possible onset of RD in patients with multiple risk factors for TD, even when SDA therapy is used.
Output: SDA
To date, there have been few reports of visual disturbances associated with BTX-B use.
Output: BTX-B
Enalapril-induced anemia in two kidney transplant recipients.
Output: Enalapril
Two renal transplant patients developed anemia during treatment of hypertension with enalapril medication.
Output: enalapril
Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis.
Output: cerivastatin
We report on a patient who developed acute rhabdomyolysis after taking cerivastatin.
Output: cerivastatin
TREATMENT/OUTCOME: Standard anti-tuberculosis therapy was administered but was complicated by interaction with cyclosporine and drug-induced cholestasis.
Output: cyclosporine
Chronic fentanyl application induces adrenocortical insufficiency.
Output: fentanyl
We report a case of a 64-year-old man with secondary adrenocortical insufficiency who has been on a chronic transdermal fentanyl treatment because of sciatic pain syndrome.
Output: fentanyl
Fluphenazine-induced neuroleptic malignant syndrome in a schizophrenic patient.
Output: Fluphenazine
Intraventricular vancomycin-induced cerebrospinal fluid eosinophilia: report of two patients.
Output: vancomycin
We propose a mechanism of vancomycin-induced mast cell degranulation and subsequent release of eosinophil chemotactic factor as a cause of CSFE.
Output: vancomycin
CONCLUSIONS: In these 3 cases, the unique positive ocular finding was corneal endothelial deposits, which may be related to the use of rifabutin.
Output: rifabutin
Corneal endothelial deposits associated with rifabutin use.
Output: rifabutin
PURPOSE: The aim of this study was to report on the possible development of corneal endothelial deposits resulting from the use of rifabutin.
Output: rifabutin
RESULTS: All cases developed corneal endothelial deposits after previous use of rifabutin.
Output: rifabutin
CASE: A malignant mixed mesodermal tumor was diagnosed in a 64-year-old woman with a bicornuate uterus while she was taking raloxifene for osteoporosis prevention.
Output: raloxifene
CONCLUSION: There may be an association between raloxifene and the development of malignant mixed mesodermal tumor.
Output: raloxifene
Malignant mixed mullerian tumor of the uterus in a patient taking raloxifene.
Output: raloxifene
We report a case of a women in whom a malignant mixed mesodermal tumor was diagnosed while she was taking raloxifene, which is also a selective estrogen receptor modulator.
Output: raloxifene
Herein we report four patients who underwent liver transplantation and developed neutropenia while receiving MMF.
Output: MMF
Mycophenolate mofetil-induced neutropenia in liver transplantation.
Output: Mycophenolate mofetil
The mean time from starting MMF to the development of neutropenia was 4 months.
Output: MMF
The side effects of MMF, such as bone marrow toxicity, have been reported.
Output: MMF
The purpose of this review is to increase awareness among physicians and other health care professionals that DIC may be a rare but potentially severe complication of anti-D IGIV treatment.
Output: anti-D IGIV
After the second infliximab infusion, he was found to have a severe transient neutropenia (0.5 x 10(9)/L).
Output: infliximab
Drug-induced agranulocytosis during treatment with infliximab in enteropathic spondyloarthropathy.
Output: infliximab
High-grade endometrial stromal sarcoma after tamoxifen therapy for breast cancer.
Output: tamoxifen
After only the third dose of pentamidine, it was noted that the patient's heart rate had decreased to 48 beats/minute.
Output: pentamidine
Clinicians should be vigilant when monitoring for cardiotoxicity in patients receiving pentamidine throughout the duration of therapy.
Output: pentamidine
Falling backward in two elderly patients taking bupropion.
Output: bupropion
RESULTS: Both patients experienced a previously unreported side effect--falling backward--associated with bupropion use.
Output: bupropion
Ophthalmologic and neurologic findings in two children exposed to vigabatrin in utero.
Output: vigabatrin
The knowledge concerning VGB-associated visual dysfunction in pediatric patients, particularly in those who have been exposed to VGB in utero is limited.
Output: VGB
Vigabatrin-induced visual field defects are at present the most important safety issue in the use of the drug.
Output: Vigabatrin
We explored ophthalmic and neurologic findings in two children who have been exposed prenatally to VGB.
Output: VGB
OBJECTIVE: To report the late development of immune-mediated diabetes mellitus after completion of alfa-interferon therapy for hepatitis C in an Asian patient.
Output: alfa-interferon
Cutaneous necrosis after injection of polyethylene glycol-modified interferon alfa.
Output: interferon alfa
Cutaneous necrosis as a result of interferon alfa is an infrequent complication with unknown pathogenesis, in which a cutaneous local immune-mediated inflammatory process might be involved.
Output: interferon alfa
Potential mechanisms involved in the occurrence of ischemic colitis in patients receiving tegaserod are also discussed.
Output: tegaserod
Tegaserod-associated ischemic colitis.
Output: Tegaserod
Lansoprazole-associated collagenous colitis: a case report.
Output: Lansoprazole
The reported case represents an unusual association between medication with the proton pump inhibitor lansoprazole and the development of collagenous colitis suggesting the importance of evaluation of drug use in patients with microscopic colitis.
Output: lansoprazole
CASE REPORT: We report a case of intracerebral hemorrhage occurring in a middle-aged man who suffered from chronic sinusitis and had been ingesting pseudoephedrine daily for one year.
Output: pseudoephedrine
Only one report links phenylpropanolamine consumption to an intracerebral hemorrhage in a patient with an AVM.
Output: phenylpropanolamine
Since 1979, over 30 published case reports have documented the relationship between phenylpropanolamine and stroke.
Output: phenylpropanolamine
This is a case of pseudoephedrine-induced intracerebral hemorrhage in a patient with an underlying vascular malformation.
Output: pseudoephedrine
Rapid onset of quetiapine-induced diabetic ketoacidosis in an elderly patient: a case report.
Output: quetiapine
Pulmonary leukostasis secondary to all-trans retinoic acid in the treatment of acute promyelocytic leukemia in first relapse.
Output: all-trans retinoic acid
Eruptive epidermoid cysts resulting from treatment with imiquimod.
Output: imiquimod
METHODS: A 79-year-old woman being treated with imiquimod 5 days per week for a nodular basal cell developed a verrucous plaque over the treatment area after 7 weeks of therapy.
Output: imiquimod
Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child.
Output: iron sucrose
The case reported here is of a child given a large dose of intravenous iron sucrose (16 mg/kg) over 3 hours, who subsequently developed features of systemic iron toxicity.
Output: iron sucrose
Five personal observations of an acute amnestic episode in younger individuals after intake of clioquinol are described together with three observations from the medical literature.
Output: clioquinol
Transient global amnesia after clioquinol: five personal observations from outside Japan.
Output: clioquinol
In the other patient, a 78-year-old woman, Neisseria mucosa knee arthritis occurred after a single sodium hyaluronate injection.
Output: sodium hyaluronate
Septic knee arthritis after intra-articular hyaluronate injection.
Output: hyaluronate
Acute dystonia induced by lamivudine.
Output: lamivudine
ADR induced by drug treatment can be a side effect of treatment with antipsychotic drugs and other drugs; however, there have been no reports of lamivudine-induced ADR in the English literature.
Output: lamivudine
The authors think that although lamivudine is widely used and well tolerated, it can cause ADRs, which are reversible after drug withdrawal.
Output: lamivudine
Pleuropulmonary fibrosis after long-term treatment with the dopamine agonist pergolide for Parkinson Disease.
Output: pergolide
OBJECTIVE: To our knowledge, this is the first published case report of an adolescent girl with a mitochondrial disorder and depression who displayed both new-onset psychotic and increased mood symptoms during treatment with risperidone.
Output: risperidone
Gemcitabine therapy has been associated with radiation recall reactions when used in the treatment of carcinoma.
Output: Gemcitabine
We report four cases of hemodynamically significant pericardial effusion in patients with refractory lymphoma who were receiving gemcitabine, all of whom had a history of mediastinal radiation without subcarinal blocking.
Output: gemcitabine
A patient with generalized MG was effectively managed with MM but developed CNS lymphoma after 3 years of treatment.
Output: MM
Despite minimal short-term side effects and apparent efficacy, chronic treatment of MG with MM may be associated with increased risk of lymphoproliferative disorders.
Output: MM
Primary CNS lymphoma complicating treatment of myasthenia gravis with mycophenolate mofetil.
Output: mycophenolate mofetil
Primary CNS lymphoma regressed on withdrawal of MM.
Output: MM
Baclofen withdrawal: a cause of prolonged fever in the intensive care unit.
Output: Baclofen
Captopril-induced pulmonary infiltrates with eosinophilia in an infant with congenital heart disease.
Output: Captopril
We report a case of an infant with complex congenital heart disease who was placed on captopril for afterload reduction following cardiac surgery and subsequently developed pulmonary infiltrates with eosinophilia.
Output: captopril
Can propofol precipitate pancreatitis in patients with Cushing's syndrome?
Output: propofol
Since elevated cortisol levels in Cushing's disease poses a threat for pancreatitis, there is a possibility that patients with Cushing's disease might be more prone to acute pancreatitis following propofol administration.
Output: propofol
CD20-negative T-cell-rich B-cell lymphoma as a progression of a nodular lymphocyte-predominant Hodgkin's lymphoma treated with rituximab: a molecular analysis using laser capture microdissection.
Output: rituximab
Recently, CD20-negative tumors have been described after Rituximab therapy.
Output: Rituximab
Transfusion haemosiderosis inspite of regular use of desferrioxamine: case report.
Output: desferrioxamine
One of the side-effects of intravitreal triamcinolone is the development of cataract, and it is known that cataract extraction can exacerbate macular degeneration.
Output: triamcinolone
Rhabdomyolysis caused by tocolysis with oral ritodrine hydrochloride in a pregnant patient with myotonic dystrophy.
Output: ritodrine hydrochloride
Rhabdomyolysis has been recognized as a complication of tocolytic therapy with ritodrine hydrochloride.
Output: ritodrine hydrochloride
We report here a rare case of ritodrine-hydrochloride-induced rhabdomyolysis in a pregnant patient with myotonic dystrophy.
Output: ritodrine-hydrochloride
Acute myocardial ischemia following accidental intravenous administration of epinephrine in high concentration.
Output: epinephrine
Inadvertent and accidental epinephrine overdose might result in potentially lethal complications.
Output: epinephrine
Polysomnographic and pharmacokinetic findings in levodopa-induced augmentation of restless legs syndrome.
Output: levodopa
We describe a patient with idiopathic RLS who developed augmentation after 8 months of levodopa treatment.
Output: levodopa
The major side effect of infliximab is infection.
Output: infliximab
This report describes a probable case of infliximab-induced membranous nephropathy.
Output: infliximab
Linezolid-induced dyserythropoiesis: chloramphenicol toxicity revisited.
Output: Linezolid
A selective association between fluoxetine and extensive, prominent eye movements in nonrapid eye movement (NREM) sleep was detected, utilizing Fisher's exact one-tailed statistic (p less than 0.00001 for each comparison).
Output: fluoxetine
Prominent positive U waves appearing with high-dose intravenous phenylephrine.
Output: phenylephrine
While on a maximal dose of phenylephrine she developed prominent positive U waves, which disappeared with the cessation of the drug.
Output: phenylephrine
Hepatoxicity is a rare complication of SRL therapy and may be connected with some diagnostic and/or therapeutic problems.
Output: SRL
Sirolimus-associated hepatotoxicity in the kidney graft recipient.
Output: Sirolimus
The aim of our paper was to describe hepatotoxicity of sirolimus (SRL) in a kidney graft recipient.
Output: sirolimus
CASE REPORT: We present a case of a 28-yr-old male who developed a severe case of nephrotic syndrome while being treated for relapsing/remitting Multiple Sclerosis (RRMS) with weekly injections of interferon beta 1a.
Output: interferon beta 1a
Nephrotic syndrome in a multiple sclerosis patient treated with interferon beta 1a.
Output: interferon beta 1a
SUBSEQUENT COURSE: The nephrosis resolved almost completely once the interferon was stopped and after immunosuppressive treatment.
Output: interferon
This latest (third) report suggests that the safety profile should be reexamined and at least raises the question of potential renal toxicity of interferons in MS.
Output: interferons
Capecitabine-induced multifocal leukoencephalopathy: a report of five cases.
Output: Capecitabine
The authors report five additional cases of capecitabine-induced multifocal leukoencephalopathy.
Output: capecitabine
A 56-year-old white woman with a diagnosis of reactive depression developed severe UI after a 30 days' treatment with venlafaxine 75 mg/day.
Output: venlafaxine
Venlafaxine-induced urinary incontinence resolved after switching to sertraline.
Output: Venlafaxine
Diagnosis of hypothyroidism during treatment can be difficult because of the common side effects of alpha interferon.
Output: alpha interferon
Sustained hypothyroidism induced by recombinant alpha interferon in patients with chronic hepatitis C.
Output: recombinant alpha interferon
Thyroid dysfunction has been reported in patients with malignant disease treated with recombinant alpha interferon.
Output: recombinant alpha interferon
Two cases of hypothyroidism in patients with chronic hepatitis C treated with recombinant alpha interferon are reported.
Output: recombinant alpha interferon
Atrial fibrillation after vardenafil therapy.
Output: vardenafil
We report a case admitted with a first-detected, symptomatic paroxysmal atrial fibrillation in a healthy patient after self-medication with vardenafil.
Output: vardenafil
We describe a case of infection with Mycobacterium abscessus in a 67-year-old woman receiving infliximab as a component of her therapy for RA.
Output: infliximab
DIAGNOSIS: Interferon alpha-2b-induced cardiomyopathy.
Output: Interferon alpha-2b
Reversible cardiomyopathy caused by administration of interferon alpha.
Output: interferon alpha
Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation.
Output: senna
We report a case of senna-induced cholestatic hepatitis which was not diagnosed at presentation.
Output: senna
Based on the history and clinical features, a diagnosis of insulin-induced lipohypertrophy was made.
Output: insulin
Insulin-induced lipohypertrophy: report of a case with histopathology.
Output: Insulin
Thus, the possible in vivo effects of insulin on adipocytes were clearly observed in this case of insulin-induced lipohypertrophy.
Output: insulin
To our knowledge, this is the first report of insulin-induced lipohypertrophy with detailed histological examinations.
Output: insulin
An objective causality assessment suggests that the JHR in our patient was probably related to penicillin.
Output: penicillin
CASE SUMMARY: A 45-year-old HIV-positive man (CD4+ count 450 cells/mm(3) and history of AIDS-defining illness) presented with JHR after an initial intravenous dose of penicillin G for presumed neurosyphilis.
Output: penicillin G
Penicillin-induced Jarisch-Herxheimer reaction.
Output: Penicillin
Acute respiratory distress syndrome after rituximab infusion.
Output: rituximab
Progressive hypoxemia mandated endotracheal intubation 1 week after rituximab administration and led to death 4 weeks after admission.
Output: rituximab
We report three cases of severe hypocalcaemia associated with i.v. bisphosphonate treatment in patients with multiple myeloma.
Output: bisphosphonate
Gemcitabine-related radiation recall in a patient with pancreatic cancer.
Output: Gemcitabine
Gemcitabine should be added to the list of drugs known to cause radiation recall.
Output: Gemcitabine
Radiation recall from gemcitabine is rare, but can potentially arise in any site that has been previously irradiated.
Output: gemcitabine
Radiation recall related to gemcitabine has been reported in lung and breast cancer.
Output: gemcitabine
We suggest discontinuing gemcitabine if radiation recall is observed.
Output: gemcitabine
A 17-year-old boy with acute lymphoblastic leukemia developed acute renal failure within 48 h of an intravenous high-dose methotrexate (5 g/m2) infusion.
Output: methotrexate
High-dose methotrexate-associated acute renal failure may be an avoidable complication.
Output: methotrexate
Methotrexate-associated nephropathy is a rare complication in pediatric oncology, and a review of the literature suggests that exposure to nephrotoxic agents may be a significant but perhaps underrecognized risk factor for its development.
Output: Methotrexate
Massive prolapse of the urethral mucosa following periurethral injection of calcium hydroxylapatite for stress urinary incontinence.
Output: calcium hydroxylapatite
To our knowledge, this is the first granulomatous reaction described after calcium hydroxylapatite injection.
Output: calcium hydroxylapatite
CASE SUMMARY: A 57-year-old female with cardiomyopathy and "sulfa" (trimethoprim/sulfamethoxazole) allergy documented as pancreatitis presented with symptoms consistent with pancreatitis after use of furosemide.
Output: furosemide
In addition, while cases of loop diuretic-induced pancreatitis, including furosemide, have been published, the allergic manifestations with both sulfonamide antibiotics and non-antibiotics in our patient suggest possible cross-reactivity between these 2 drug classes.
Output: furosemide
Torsemide appears to also be a part of a long list of agents that can cause pancreatitis.
Output: Torsemide
On the 3rd day, an inferior vena cava (IVC) filter was placed with a heparin flush, after which massive IVC thrombosis developed.
Output: heparin
When thrombosis develops during heparin treatment, it is important to suspect HITTs and to assay for the associated antibodies, regardless of the actual platelet count.
Output: heparin
After gastric-outlet obstruction was recognized in several infants who received prostaglandin E1, we studied the association between the drug and this complication.
Output: prostaglandin E1
Reversible posterior leukoencephalopathy syndrome in systemic lupus erythematosus with thrombocytopenia treated with cyclosporine.
Output: cyclosporine