niryuu/sni-each-converted huggingface dataset:
The exophthalmos improved dramatically within 72 hours of the withdrawal of lithium.
Output: lithium
Severe abdominal pain in low dosage clofazimine.
Output: clofazimine
We describe a 41 yr old leprosy patient treated for 10 yrs with clofazimine who underwent laparotomy for severe abdominal pain.
Output: clofazimine
Amphotericin B overdose in pediatric patients with associated cardiac arrest.
Output: Amphotericin B
CONCLUSIONS: Amphotericin B overdose can be fatal in children and infants.
Output: Amphotericin B
INTERVENTIONS AND RESULTS: Cardiac complications were observed in five pediatric patients who received between 4.6 and 40.8 mg/kg/d of amphotericin B.
Output: amphotericin B
OBJECTIVE: To report the first five cases of amphotericin B overdose with secondary cardiac complications in a pediatric population.
Output: amphotericin B
Sudden death in an infant from methemoglobinemia after administration of "sweet spirits of nitre".
Output: sweet spirits of nitre
L-Carnitine supplementation has been recommended to prevent the fatal hepatotoxic effects associated with valproic acid.
Output: valproic acid
A case is reported of a 40 year old woman treated with intraventricular IL-2 for leptomeningeal disease who developed progressive cognitive dysfunction.
Output: IL-2
Delayed neurotoxicity of intraventricular interleukin-2: a case report.
Output: interleukin-2
Albeit rare among Western patients, such lithium-associated thyroid dysfunctions appeared to be more likely to occur in Hong Kong Chinese.
Output: lithium
Four Chinese female patients who suffered from manic-depressive disorder and underlying autoimmune thyroiditis developed transient episodes of thyrotoxicosis during maintenance lithium therapy.
Output: lithium
Lithium-associated transient thyrotoxicosis in 4 Chinese women with autoimmune thyroiditis.
Output: Lithium
They seemed to involve multiple aetiological factors, such as autoimmune thyroid disease, the toxic and immunomodulatory roles of lithium and perhaps genetic and dietary factors.
Output: lithium
CONCLUSIONS: It is probable that foscarnet contributed to the electrolyte disorders and symptomatology in this patient.
Output: foscarnet
DISCUSSION: Electrolyte disorders associated with foscarnet are reviewed.
Output: foscarnet
Interference with the cortisol axis by the microtubule antagonist, CPH82.
Output: CPH82
Carbamazepine-induced tics.
Output: Carbamazepine
In the third child, the tics ceased after CBZ discontinuation.
Output: CBZ
These cases demonstrate that CBZ can induce simple motor tics in children.
Output: CBZ
We report 3 children with epilepsy who developed facial motor tics after initiation of CBZ for complex partial seizures.
Output: CBZ
Acyclovir-induced neurotoxicity: concentration-side effect relationship in acyclovir overdose.
Output: Acyclovir
A 16-year-old white male with acute biphenotypic leukemia developed evidence of the eosinophilia myalgia syndrome associated with total parenteral nutritional support with solutions containing tryptophan, which were given during his initial induction chemotherapy and also after autologous marrow transplantation.
Output: tryptophan
Fatal eosinophilia myalgia syndrome in a marrow transplant patient attributed to total parenteral nutrition with a solution containing tryptophan.
Output: tryptophan
Thus, the eosinophilia myalgia syndrome can be associated with parenteral tryptophan administration.
Output: tryptophan
A patient with acute esophageal variceal bleeding developed fatal rhabdomyolysis during treatment with a continuous intravenous infusion of vasopressin.
Output: vasopressin
Rhabdomyolysis associated with the use of intravenous vasopressin.
Output: vasopressin
These multiple overlapping factors probably lead to rhabdomyolysis in a minority of patients receiving vasopressin infusion.
Output: vasopressin
In one case, disulfiram was the only potential teratogen exposed to the fetus.
Output: disulfiram
Nonspecific but significant abnormalities have been described in the infants of women treated with disulfiram in the first trimester of their pregnancies.
Output: disulfiram
Although the essential cause of PV is unclear, its onset has occasionally been associated with drug therapy, in particular penicillamine.
Output: penicillamine
Pemphigus vulgaris precipitated by glibenclamide therapy.
Output: glibenclamide
The patient described in this paper was a 78-year-old diabetic man who developed oral lesions of PV following institution of glibenclamide therapy.
Output: glibenclamide
Piritrexim-induced pulmonary toxicity.
Output: Piritrexim
The pulmonary toxicity is probably induced by piritrexim.
Output: piritrexim
Acceleration of ventricular response to atrial flutter after intravenous adenosine.
Output: adenosine
Lymphoma developing in a patient with rheumatoid arthritis taking methotrexate.
Output: methotrexate
The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoproliferative diseases, but coincidence cannot be excluded.
Output: methotrexate
We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period.
Output: methotrexate
Hepatotoxicity of paracetamol enhanced by ingestion of alcohol: report of two cases.
Output: paracetamol
Two fatal cases of poisoning by paracetamol are described.
Output: paracetamol
We report a case of drug-induced Kaposi's sarcoma (KS) on the sole of the right foot in a 71-year-old man, treated for 6 months with corticosteroid therapy (prednisolone 25 mg/day) for pericardial effusion.
Output: prednisolone
Acute dystonic reaction with low-dose pimozide.
Output: pimozide
Intravenous haloperidol is generally well tolerated, but multiform ventricular tachycardia has been reported.
Output: haloperidol
All developed mucocutaneous side effects within 20 weeks of beginning im gold therapy, at a time when RA had improved markedly compared to pretreatment status.
Output: gold
How low can you go? Use of very low dosage of gold in patients with mucocutaneous reactions.
Output: gold
Anterior spinal artery syndrome--a complication of cervical intrathecal phenol injection.
Output: phenol
We have seen a case of terminal malignant melanoma in which clinical manifestations, indicative of anterior spinal artery syndrome, developed following the injection of 0.3 ml of 10% phenol-glycerine into the cervical subarachnoid space at the C4--C5 level for the control of severe right arm pain.
Output: phenol-glycerine
Azathioprine can cause severe myelosuppression.
Output: Azathioprine
Azathioprine-induced myelosuppression due to thiopurine methyltransferase deficiency in a patient with autoimmune hepatitis.
Output: Azathioprine
The azathioprine dose was low (1 mg/kg) and pancytopenia occurred after 56 days therapy.
Output: azathioprine
Thiopurine methyltransferase deficiency occurs at a frequency of one in 300 and is associated with profound myelosuppression after a short course of azathioprine.
Output: azathioprine
We describe the first documented case of azathioprine-induced severe myelosuppression due to thiopurine methyltransferase deficiency in autoimmune liver disease.
Output: azathioprine
Nabumetone-associated interstitial nephritis.
Output: Nabumetone
She had been taking nabumetone for 6 months, but had discontinued the agent 2 weeks before admission due to progressive edema.
Output: nabumetone
Acute myeloid leukemia evolving from essential thrombocythemia in two patients treated with hydroxyurea.
Output: hydroxyurea
In this report, two cases of ET which evolved into AL without prior exposure to radiation or alkylating agents, and which were treated with long-term hydroxyurea therapy, are described.
Output: hydroxyurea
Prolonged used of hydroxyurea in patients with ET may lead to therapy-associated acute leukemia.
Output: hydroxyurea
In the present paper, we discuss the first Japanese vivax malaria patient whose QT interval was prolonged after treatment with halofantrine.
Output: halofantrine
Prolongation of the QT interval observed in a Japanese patient with vivax malaria following treatment with halofantrine.
Output: halofantrine
Supravenous hyperpigmentation in association with CHOP chemotherapy of a CD30 (Ki-1)-positive anaplastic large-cell lymphoma.
Output: CHOP
We report an unusual pattern of supravenous hyperpigmentation occurring after CHOP chemotherapy.
Output: CHOP
Phenytoin toxicity due to concomitant antituberculosis therapy.
Output: Phenytoin
Seventy-four per cent of patients with epileptogenic disorders seen at the Emergency Unit at Groote Schuur Hospital were on phenytoin and 11.6% of these had blood levels in the toxic range.
Output: phenytoin
Slow acetylators, who comprise roughly 50% of the South African population, are likely to develop clinical and biochemical features of phenytoin toxicity when this drug is given together with antituberculosis therapy.
Output: phenytoin
No cases of renal acidosis, and only one case of nephrogenic diabetes insipidus, has been previously reported as a complication of foscarnet treatment.
Output: foscarnet
Choroidal hemorrhage associated with systemic tissue plasminogen activator.
Output: tissue plasminogen activator
PURPOSE: To determine the cause of spontaneous choroidal hemorrhage in a 67-year-old man after a myocardial infarction and administration of tissue plasminogen activator.
Output: tissue plasminogen activator
Accelerated nodulosis during methotrexate therapy for juvenile rheumatoid arthritis.
Output: methotrexate
Physicians treating patients with methotrexate for juvenile rheumatoid arthritis must be aware of this extraarticular side effect.
Output: methotrexate
The nodules regressed after withdrawal of methotrexate therapy in one patient and were arrested with the addition of hydroxychloroquine in the other.
Output: methotrexate
We describe two patients with rheumatoid factor-positive, polyarticular-onset juvenile rheumatoid arthritis in whom accelerated nodulosis developed during methotrexate therapy.
Output: methotrexate
Jaundice induced by streptokinase.
Output: streptokinase
Only a few reports of overt jaundice are associated with streptokinase.
Output: streptokinase
Although both patients recovered from the colitis after the administration of vancomycin, the first case demonstrated a relapse of the colitis after receiving a subsequent course of the same chemotherapy with cisplatin.
Output: cisplatin
Based on our findings, it is thus concluded that cisplatin may cause C. difficile colitis.
Output: cisplatin
Both patients were then treated with a carboplatin alternative to cisplatin in the following courses, which resulted in neither a relapse of the colitis nor a recurrence of the malignancies up to this time.
Output: cisplatin
Clostridium difficile colitis associated with cisplatin-based chemotherapy in ovarian cancer patients.
Output: cisplatin
Severe C. difficile colitis occurred in 2 patients (6.1%) after receiving cisplatin-based combination chemotherapy for ovarian malignancies.
Output: cisplatin
The purpose of this study was to examine the incidence and cause of Clostridium difficile colitis occurring after cisplatin-based combination chemotherapy in ovarian cancer patients.
Output: cisplatin
A patient with severe cholestatic jaundice induced by captopril is presented.
Output: captopril
Captopril-associated "pseudocholangitis'.
Output: Captopril
Captopril is known to be associated with dermatologic, hematologic, and pulmonary adverse effects.
Output: Captopril
Development of nephrotic syndrome in a patient with acute myeloblastic leukemia after treatment with macrophage-colony-stimulating factor.
Output: macrophage-colony-stimulating factor
It should be emphasized that the recurrence of nephrotic syndrome was observed after the following chemotherapy, including M-CSF, whereas the bone marrow still remained completely remitted.
Output: M-CSF
These evolutional changes in both proteinuria and glomerular histology suggest a close linkage between the M-CSF treatment and macrophage-related glomerular injury.
Output: M-CSF
Milk-alkali syndrome induced by 1,25(OH)2D in a patient with hypoparathyroidism.
Output: 1,25(OH)2D
CONCLUSIONS: There was a temporal relationship between the onset of nonconvulsive status epilepticus and initiation of ifosfamide infusion.
Output: ifosfamide
DISCUSSION: Central nervous system (CNS) toxicity has been described with ifosfamide, with most cases reported in the pediatric population.
Output: ifosfamide
Ifosfamide-induced nonconvulsive status epilepticus.
Output: Ifosfamide
OBJECTIVE: To describe a patient with ifosfamide-induced nonconvulsive status epilepticus.
Output: ifosfamide
This represents the first report of nonconvulsive status epilepticus induced by ifosfamide.
Output: ifosfamide
Albendazole-induced pseudomembranous colitis.
Output: Albendazole
Although a few case reports link metronidazole with the development of pseudomembranous colitis, albendazole has not been associated with the development of this condition.
Output: metronidazole
Oculomotor disturbances associated with 5-fluorouracil chemotherapy.
Output: 5-fluorouracil
Assessment of cortisol response was by insulin-induced hypoglycaemia in three cases, by short tetracosactrin test in two, and by low-dose tetracosactrin and 24-hour urinary cortisol/creatinine ratio in one.
Output: insulin
Growth and adrenal suppression in asthmatic children treated with high-dose fluticasone propionate.
Output: fluticasone propionate
METHODS: Growth retardation was observed in six severely asthmatic children after introduction of high-dose fluticasone propionate treatment (dry powder).
Output: fluticasone propionate
Metipranolol associated granulomatous anterior uveitis: not so uncommon as thought.
Output: Metipranolol
Two case reports of bilateral granulomatous anterior uveitis are described in patients with open angle glaucoma treated with metripranolol 0.6% eye drops.
Output: metripranolol
Intranasal desmopressin-induced hyponatremia.
Output: desmopressin
Within 24 hours of fluid restriction and cessation of desmopressin, her symptoms and hyponatremia resolved.
Output: desmopressin
Does acyclovir increase serum lithium levels?
Output: acyclovir
Dapsone syndrome in cutaneous lupus erythematosus.
Output: Dapsone
Physicians should be aware of the potentially lethal side effects of dapsone.
Output: dapsone
A case is presented which illustrates a probably fatal interaction between minoxidil and a coagulation disorder.
Output: minoxidil
Potential mechanisms regarding the pathophysiology of lithium-associated CDI are discussed.
Output: lithium
This case emphasizes the importance of the evaluation of lithium-associated polyuria with a direct measurement of plasma vasopressin, interpreted with simultaneous plasma and urine osmolality to secure the correct diagnosis and ensure appropriate therapeutic management.
Output: lithium
Transient central diabetes insipidus in the setting of underlying chronic nephrogenic diabetes insipidus associated with lithium use.
Output: lithium
We report a patient receiving chronic lithium therapy who presented with a transient CDI occurring in the setting of underlying chronic NDI.
Output: lithium
CONCLUSIONS: Jet-injection devices might constitute a helpful method to treat those patients affected by severe human insulin-induced lipoatrophy.
Output: human insulin
Human insulin-induced lipoatrophy.
Output: Human insulin
OBJECTIVE: To evaluate the efficacy of the administration of insulin by a jet-injector device in stopping and reversing severe human insulin-induced lipoatrophy.
Output: human insulin
Improved awareness of and further investigation into the neurotoxic effects of ofloxacin may enhance its safe use.
Output: ofloxacin
Seizures associated with ofloxacin therapy.
Output: ofloxacin
We describe four patients who had seizures while receiving ofloxacin; no other causes were evident.
Output: ofloxacin
Systemic corticosteroids in the phenytoin hypersensitivity syndrome.
Output: phenytoin
A patient is described who developed a poorly differentiated sarcoma after cyclophosphamide was used to treat his rheumatoid arthritis.
Output: cyclophosphamide
Sarcoma complicating therapy with cyclophosphamide.
Output: cyclophosphamide
A chronic reaction associated with long-term treatment with nitrofurantoin has also been reported and causes irreversible pulmonary fibrosis.
Output: nitrofurantoin
Despite the known pulmonary side effects of nitrofurantoin, there is no report of this toxicity occurring in pregnant patients.
Output: nitrofurantoin
Nitrofurantoin-induced pulmonary toxicity during pregnancy: a report of a case and review of the literature.
Output: Nitrofurantoin
We present a case of respiratory failure occurring in a woman at 16 weeks' gestation who was being treated with nitrofurantoin for a urinary tract infection.
Output: nitrofurantoin
Methemoglobinemia is another common finding among patients receiving dapsone therapy, but rarely does it result in prominent symptoms other than transient pallor.
Output: dapsone
Acetazolamide-accelerated anticonvulsant osteomalacia.
Output: Acetazolamide
Acetazolamide may have accelerated the development of osteomalacia by several mechanisms, including increased renal calcium excretion.
Output: Acetazolamide
The delayed encephalopathy developed 9 and 22 months respectively after the first dose of intrathecal methotrexate.
Output: methotrexate
A retrospective study was conducted of 40 loperamide poisoning cases recorded at the Centre National d'Informations Toxicologiques Veterinaires.
Output: loperamide
Loperamide poisoning in the dog.
Output: Loperamide
a 67-year-old man with bipolar disorder developed a Creutzfeldt-Jakob like syndrome during lithium carbonate treatment.
Output: lithium carbonate
Lithium-induced Creutzfeldt-Jakob syndrome.
Output: Lithium
We also describe a new, noninvasive method to assess magnesium-induced neuromuscular block when curariform muscle relaxant was given simultaneously.
Output: magnesium
Hepatobiliary disorders associated with orally administered terbinafine have rarely been reported.
Output: terbinafine
Terbinafine-induced cholestatic liver disease.
Output: Terbinafine
We describe a case of prolonged terbinafine-induced cholestatic liver disease.
Output: terbinafine
An unusual case of Ecstasy poisoning.
Output: Ecstasy
We describe a case of poisoning with 3,4-methylenedioxymet-amphetamine Ecstasy that presented with all the features suggestive of a fatal outcome, including a creatinine phosphokinase level markedly higher than any previously reported.
Output: 3,4-methylenedioxymet-amphetamine Ecstasy
However, dermatologists should be cautious about a photosensitivity reaction induced by mequitazine or other phenothiazine-derivative drugs.
Output: mequitazine
Mequitazine seemed to play a part similar to chlorpromazine, and absence of mequitazine-induced photosensitivity may be due to a relatively low dosage of the drug.
Output: mequitazine
Two cases of mequitazine-induced photosensitivity reactions.
Output: mequitazine
Keratitis in methamphetamine abusers.
Output: methamphetamine
Methamphetamine's extensive physiologic effects, inconsistent street purity, and multiple routes of administration offer many possibilities for injury to the cornea.
Output: Methamphetamine
We report four cases of severe corneal ulceration in methamphetamine abusers.
Output: methamphetamine
CONCLUSIONS: This study confirmed that in most patients MTX-induced liver cirrhosis is not aggressive.
Output: MTX
Methotrexate-induced liver cirrhosis.
Output: Methotrexate
However, other factors or drugs (e.g. cresol) are thought to induce MH.
Output: cresol
This case supports the assessment that MH and diabetes are associated diseases and that cresol could possibly trigger MH.
Output: cresol
The use of beclomethasone diproprionate inhaler complicated by the development of an eosinophilic pneumonia reaction.
Output: beclomethasone diproprionate
Fatal intravascular autoimmune hemolytic anemia after fludarabine treatment for chronic lymphocytic leukemia.
Output: fludarabine
The occurrence of severe AIHA in CLL patients treated with fludarabine has been reported by several authors.
Output: fludarabine
When the patient was treated again with fludarabine nine months later, the DAT became positive with anti-IgG and anti-C3d antiglobulins after the second course of treatment.
Output: fludarabine
She had just finished a 3-week course of intravenous tobramycin for bronchiectasis and had an elevated serum tobramycin trough level 1 week before the onset of tetany.
Output: tobramycin
Tetany in a child with AIDS receiving intravenous tobramycin.
Output: tobramycin
This pattern is suggestive of renal toxicity due to tobramycin.
Output: tobramycin
Insulin-induced lipoatrophy in type I diabetes.
Output: Insulin
OBJECTIVE: To test the hypothesis that tumor necrosis factor (TNF)-alpha may mediate the loss and the dedifferentiation of subcutaneous fat tissue in the insulin-induced lipoatrophies of a diabetic patient who presented extensive lesions.
Output: insulin
Methotrexate is an effective but potentially toxic treatment for psoriasis.
Output: Methotrexate
After treatment with cimetidine, there was a rapid deterioration with decreased oxygen saturation and arterial PO2 values.
Output: cimetidine
Hypoxemia improved during continuous tolazoline infusion, but gastrointestinal bleeding occurred.
Output: tolazoline
Acute nitrite toxicity results from industrial exposure, accidental ingestion (e.g., abuse of organic nitrites as an aphrodisiac, especially in the male homosexual population), and suicidal ingestion.
Output: nitrite
Infants are particularly susceptible to chronic nitrate-induced methemoglobinemia because of their low stomach acid production, large numbers of nitrite-reducing bacteria, and the relatively easy oxidation of fetal hemoglobin.
Output: nitrate
Acute esmolol toxicity may be self-limiting because of its extremely short half-life.
Output: esmolol
After induction of general anesthesia and administration of a standard dose of intravenous esmolol hydrochloride, her cardiac rhythm progressed to asystole.
Output: esmolol hydrochloride
Cardiac arrest after esmolol administration: a review of acute beta-blocker toxicity.
Output: esmolol
Atenolol induced memory impairment: a case report.
Output: Atenolol
His impaired memory was found to be due to the atenolol he was on and he made a complete recovery on withdrawing the beta-blocker.
Output: atenolol
A potential role for renal and hepatic impairment in the observed protracted course of amiodarone-induced thyrotoxicosis is suggested.
Output: amiodarone
Failure of plasmapheresis, corticosteroids and thionamides to ameliorate a case of protracted amiodarone-induced thyroiditis.
Output: amiodarone
We report a case of amiodarone-induced thyrotoxicosis of protracted duration, unresponsive to conventional thionamide therapy, with therapy limited by severe adverse drug reactions.
Output: amiodarone
Psychotic disorder associated with isoniazid.
Output: isoniazid
We evaluated a patient who developed a psychotic disorder after 4 months of isoniazid prophylaxis for a positive tuberculosis tine test.
Output: isoniazid
Ketanserin in the treatment of protamine-induced pulmonary hypertension.
Output: protamine
METHODS/RESULTS: This paper presents a new case of rifabutin uveitis and a review of the various published reports to date.
Output: rifabutin
over the past 3 years there have been several reports of uveitis associated with rifabutin therapy.
Output: rifabutin
Uveitis associated with rifabutin therapy: a clinical alert.
Output: rifabutin
CASE DESCRIPTION: A 59-year-old man with known neurocysticercosis developed a large cerebral infarction during praziquantel therapy.
Output: praziquantel
Large cerebral infarction during praziquantel therapy in neurocysticercosis.
Output: praziquantel
Dihydropyrimidine dehydrogenase deficiency: a pharmacogenetic defect causing severe adverse reactions to 5-fluorouracil-based chemotherapy.
Output: 5-fluorouracil
Mesalamine-induced hypersensitivity pneumonitis.
Output: Mesalamine
Mesalamine may cause hypersensitivity pneumonitis in patients with Crohn's disease.
Output: Mesalamine
Immunosuppression elicited by the extensive administration of prednisolone was suspected for the initiation of the generalized mite infestation.
Output: prednisolone
CONCLUSION: The findings in these two patients suggest that colchicine may delay corneal wound healing.
Output: colchicine
Delay of corneal wound healing in patients treated with colchicine.
Output: colchicine
The authors report on two patients with corneal ulcers refractory to conventional treatment while the patients were undergoing oral colchicine therapy.
Output: colchicine
The authors suggest that in patients with corneal ulcers refractory to conventional treatment who are receiving colchicine, cessation of colchicine therapy should be considered.
Output: colchicine
Fulminant hepatic failure associated with bicalutamide.
Output: bicalutamide
Delayed hypersensitivity to flurbiprofen.
Output: flurbiprofen
CONCLUSION: While thrombosis has been reported with GnRH-a therapy in men with prostate cancer, its association with treatment in this benign case may have been a consequence of the massive tumor size.
Output: GnRH-a
Case study: adverse response to clonidine.
Output: clonidine
Four cases of adverse experiences with clonidine are described.
Output: clonidine
Discontinuation of the itraconazole caused resolution of the drug eruption.
Output: itraconazole
Nonsustained polymorphous ventricular tachycardia during amiodarone therapy for atrial fibrillation complicating cardiomyopathy.
Output: amiodarone
The probable proarrhythmic action of amiodarone, although rare, is reviewed along with a discussion of the novel use of intravenous magnesium sulfate therapy.
Output: amiodarone
Acute asthma associated with sustained-release verapamil.
Output: verapamil
OBJECTIVE: To describe a patient with asymptomatic bronchial asthma and hypertension who developed an acute asthma attack after receiving sustained-release verapamil.
Output: verapamil
She continued taking verapamil for 6 months, then, on her own, stopped all medications including the sustained-release verapamil, and her asthma symptoms disappeared.
Output: verapamil
Cephalexin rash in infectious mononucleosis.
Output: Cephalexin
The ampicillin rash occurring in cases of infectious mononucleosis is well documented.
Output: ampicillin
The case of a patient with infectious mononucleosis treated with cephalexin who later showed a rash is presented and the previous literature is reviewed.
Output: cephalexin
A possible case of carbamazepine induced pancreatitis.
Output: carbamazepine
Methotrexate-induced pneumonitis in patients with rheumatoid arthritis and psoriatic arthritis: report of five cases and review of the literature.
Output: Methotrexate
On the other hand, MTX-induced pneumonitis seems to be very rare in psoriatic arthritis (PsA).
Output: MTX
Our review of 194 RA patients and 38 PsA patients receiving MTX has identified four RA patients and one PsA patient with MTX-induced pneumonitis, giving a prevalence of 2.1% and 0.03%, respectively.
Output: MTX
Pneumonitis is emerging as one of the most unpredictable and potentially serious, adverse effects of treatment with MTX.
Output: MTX
The presence of a lymphocyte alveolitis with a predominance of CD4+ T cells in 3 RA patients and CD8+ T cells with a concomitant increase in neutrophils in another case suggests that immunologically mediated reactions may be one damage mechanism in MTX-induced pneumonitis.
Output: MTX
Recent studies have shown that under experimental conditions ferrous sulfate may reduce the gastrointestinal absorption of orally administered levothyroxine sodium in patients with primary hypothyroidism.
Output: ferrous sulfate
We describe a patient who became hypothyroid while taking ferrous sulfate.
Output: ferrous sulfate
However, as the use of hepatitis B vaccination is growing, adverse side effects, including mental nerve neuropathy, should be observed with an increased frequency.
Output: hepatitis B vaccination
Mental nerve neuropathy as a result of hepatitis B vaccination.
Output: hepatitis B vaccination
Although its side effects are few, tamoxifen increases the incidence of proliferative lesions of the endometrium, which theoretically should be preventable with progestational agents.
Output: tamoxifen
An elderly man with procainamide hydrochloride-induced lupus syndrome had a circulating anticoagulant against factor XI and a biologic false-positive (BFP) test result for syphilis.
Output: procainamide hydrochloride
Circulating anticoagulant in the procainamide-induced lupus syndrome.
Output: procainamide
Clinical signs of hypermagnesemia are an uncommon complication following oral administration of magnesium sulfate.
Output: magnesium sulfate
Establishment of diuresis with fluids and IV administration of calcium may provide successful treatment of magnesium toxicosis in horses.
Output: magnesium
Magnesium toxicosis in two horses.
Output: Magnesium
CASE SUMMARIES: In each case, the patients were treated over 5 years with lovastatin and developed rhabdomyolysis that coincided with the completion of a prescribed regimen of a newer macrolide antibiotic.
Output: lovastatin
DISCUSSION: Rhabdomyolysis is a clinical syndrome resulting from the destruction of skeletal muscle that may progress to renal failure Several drugs have been associated with rhabdomyolysis, including lovastatin, a hydroxymethylglutaryl-coenzyme A reductase inhibitor.
Output: lovastatin
These cases were considered unusual in light of the short delay of their onset after initiation of immunosuppressive therapy and their fulminant course: 3 of these patients died of PCP occurring during the first month of treatment with prednisone.
Output: prednisone
Acute leukaemia during tamoxifen therapy.
Output: tamoxifen
Tamoxifen is suggested to be carcinogenic both through direct genotoxic and epigenetic mechanisms.
Output: Tamoxifen
Relapse in the external auditory canal of acute promyelocytic leukemia after treatment with all-trans retinoic acid.
Output: all-trans retinoic acid
This case suggests the importance of careful observation for extramedullary relapse in patients who are treated with ATRA.
Output: ATRA
Generalized maculopapular and papular purpuric eruptions are perhaps the most common thionamide-induced reactions.
Output: thionamide
Propylthiouracil-induced cutaneous vasculitis.
Output: Propylthiouracil
The observation of cutaneous vasculitis during administration of propylthiouracil suggested that clinical awareness of this complication should be of considerable importance.
Output: propylthiouracil
A 2-year-old mentally retarded boy with frontal lobe epilepsy presented with an episode that resembled heat stroke during the administration of zonisamide.
Output: zonisamide
Heat stroke-like episode in a child caused by zonisamide.
Output: zonisamide
The oligohidrosis caused by zonisamide was reversible in that the patient regained the ability to sweat within 2 weeks of the cessation of drug administration.
Output: zonisamide
Acute renal failure in a patient receiving treatment with suramin.
Output: suramin
Acute renal failure should be recognized as a potential complication of suramin treatment.
Output: suramin
Other potential causes of renal failure were not present in our patient and his renal function gradually recovered with the cessation of suramin treatment.
Output: suramin
We describe a patient with metastatic prostate cancer who developed nonoliguric renal failure during treatment with suramin.
Output: suramin
Clozapine induced polyserositis.
Output: Clozapine
When the disease recurred conventional amphotericin B was used again, but had to be stopped because of severe side effects.
Output: amphotericin B
CONCLUSION: We believe this to be the first reported case of rhGH-induced hypercalcemia in an HIV-infected patient.
Output: rhGH
Hypercalcemia in an AIDS patient treated with growth hormone.
Output: growth hormone
The hypercalcemia responded to discontinuation of rhGH and a single dose of intravenous pamidronate disodium and has not recurred in 8 months of follow-up.
Output: rhGH
We report a male patient with advanced AIDS who developed hypercalcemia 2 weeks after institution of rhGH therapy.
Output: rhGH
Hypersensitivity reactions to cisplatin following multiple uncomplicated courses: a report on two cases.
Output: cisplatin
We report an unusually short lived and asymptomatic episode of severe cisplatin-induced renal tubular salt wasting in a fit 41-year-old patient with malignant teratoma.
Output: cisplatin