Context: -lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics, consisting of all antibiotic agents that contain a beta-lactam ring in their molecular structures. This includes penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems. Most -lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organism and are the most widely used group of antibiotics. Until 2003, when measured by sales, more than half of all commercially available antibiotics in use were -lactam compounds., Norman George Heatley ( 10 January 1911 -- 5 January 2004 ) was a member of the team of Oxford University scientists who developed penicillin . Norman Heatley developed the back extraction technique for efficiently purifying penicillin in bulk ., Oxford is a city in the South East region of England and the county town of Oxfordshire. With a population of 159,994 it is the 52nd largest city in the United Kingdom, and one of the fastest growing and most ethnically diverse. The city is situated from London, from Bristol, from both Southampton and Birmingham and from Reading., Penicillin (PCN or pen) is a group of antibiotics which include penicillin G (intravenous use), penicillin V (use by mouth), and procaine penicillin, and benzathine penicillin (intramuscular use). Penicillin antibiotics were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. Penicillins are still widely used today, though many types of bacteria have developed resistance following extensive use.
About 10% of people report that they are allergic to penicillin; however, up to 90% of this group may not actually be allergic. Serious allergies only occur in about 0.03%. All penicillins are -lactam antibiotics.
Penicillin was discovered in 1928 by Scottish scientist Alexander Fleming. People began using it to treat infections in 1942. There are several enhanced penicillin families which are effective against additional bacteria; these include the antistaphylococcal penicillins, aminopenicillins and the antipseudomonal penicillins. They are derived from "Penicillium" fungi., Southampton, on the south coast of England, is the largest city in the ceremonial county of Hampshire. It is south-west of London and north-west of Portsmouth. Southampton is a major port and the closest city to the New Forest. It lies at the northernmost point of Southampton Water at the confluence of the Rivers Test and Itchen, with the River Hamble joining to the south of the urban area. The city, which is a unitary authority, has an estimated population of 253,651. The city's name is sometimes abbreviated in writing to "So'ton" or "Soton", and a resident of Southampton is called a ., Sir Alexander Fleming (6 August 188111 March 1955) was a Scottish biologist, pharmacologist and botanist. His best-known discoveries are the enzyme lysozyme in 1923 and the world's first antibiotic substance benzylpenicillin (Penicillin G) from the mould "Penicillium notatum" in 1928, for which he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Boris Chain. He wrote many articles on bacteriology, immunology, and chemotherapy. , London is the capital and most populous city of England and the United Kingdom, as well as the most populous city proper in the European Union. Standing on the River Thames in the south east of the island of Great Britain, London has been a major settlement for two millennia. It was founded by the Romans, who named it "Londinium". London's ancient core, the City of London, largely retains its medieval boundaries. Since at least the 19th century, "London" has also referred to the metropolis around this core, historically split between Middlesex, Essex, Surrey, Kent, and Hertfordshire, which today largely makes up Greater London, governed by the Mayor of London and the London Assembly., Birmingham is a major city and metropolitan borough of West Midlands, England. It is the largest and most populous British city outside London, with a population in 2014 of 1,101,360. The city is in the West Midlands Built-up Area, the third most populous urban area in the United Kingdom, with a population of 2,440,986 at the 2011 census. Birmingham's metropolitan area is the second most populous in the UK with a population of 3.8 million. This also makes Birmingham the 9th most populous metropolitan area in Europe., Bristol is a city, unitary authority area and county in South West England with an estimated population of 449,300 in 2016. It is England's sixth and the United Kingdom's eighth most populous city, and the most populous city in Southern England after London. The city borders the Unitary Authority areas of North Somerset and South Gloucestershire, with the historic cities of Bath and Gloucester to the south-east and north-east, respectively., Penicillium is a genus of ascomycetous fungi of major importance in the natural environment as well as food and drug production., Subject: norman heatley, Relation: occupation, Options: (A) biologist (B) botanist (C) major (D) mayor (E) sales (F) scientist (G) united kingdom
Output: biologist