Context: Sextus Afranius Burrus (born AD 1 in Vasio, Gallia Narbonensis; died AD 62) was a prefect of the Praetorian Guard and was, together with Seneca the Younger, an advisor to the Roman emperor Nero, making him a very powerful man in the early years of Nero's reign., Faenius Rufus, an eques Romanus, was praefectus annonae from AD 55 to 62. Tacitus reports that (unlike most holders of that office) he did "not" profit from it. With Tigellinus, he succeeded Sextus Afranius Burrus as praetorian prefect in AD 62. Rufus had a close association with Agrippina the Younger. In 65, however, he was executed for his part as a member of the Pisonian conspiracy against the Emperor Nero., Ofonius Tigellinus, also known as Tigellinus Ofonius, Ophonius Tigellinus and Sophonius Tigellinus (c. 1069), was a prefect of the Roman imperial bodyguard, known as the Praetorian Guard, from 62 until 68, during the reign of emperor Nero. Tigellinus gained imperial favour through his acquaintance with Nero's mother Agrippina the Younger, and was appointed prefect upon the death of his predecessor Sextus Afranius Burrus, a position Tigellinus held first with Faenius Rufus and then Nymphidius Sabinus., A mental disorder, also called a mental illness or psychiatric disorder, is a diagnosis by a mental health professional of a behavioral or mental pattern that may cause suffering or a poor ability to function in life. Such features may be persistent, relapsing and remitting, or occur as a single episode. Many disorders have been described, with signs and symptoms that vary widely between specific disorders.
The causes of mental disorders are often unclear. Theories may incorporate findings from a range of fields. Mental disorders are usually defined by a combination of how a person behaves, feels, perceives, or thinks. This may be associated with particular regions or functions of the brain, often in a social context. A mental disorder is one aspect of mental health. Cultural and religious beliefs, as well as social norms, should be taken into account when making a diagnosis.
Services are based in psychiatric hospitals or in the community, and assessments are carried out by psychiatrists, clinical psychologists, and clinical social workers, using various methods but often relying on observation and questioning. Treatments are provided by various mental health professionals. Psychotherapy and psychiatric medication are two major treatment options. Other treatments include social interventions, peer support, and self-help. In a minority of cases there might be involuntary detention or treatment. Prevention programs have been shown to reduce depression.
Common mental disorders include depression, which affects about 400 million, dementia which affects about 35 million, and schizophrenia, which affects about 21 million people globally. Stigma and discrimination can add to the suffering and disability associated with mental disorders, leading to various social movements attempting to increase understanding and challenge social exclusion. , Suicide is the act of intentionally causing one's own death. Risk factors include mental disorders such as depression, bipolar disorder, schizophrenia, personality disorders, alcoholism, or substance misuse. Others are impulsive acts due to stress such as from financial difficulties, troubles with relationships, or from bullying. Those who have previously attempted suicide are at higher risk for future attempts. Suicide prevention efforts include limiting access to method of suicide, such as firearms and poisons, treating mental disorders and substance misuse, proper media reporting of suicide, and improving economic conditions. Although crisis hotlines are common, there is little evidence for their effectiveness.
The most commonly used method of suicide varies between countries, and is partly related to the availability of effective means. Common methods include hanging, pesticide poisoning, and firearms. Suicide resulted in 842,000 deaths globally in 2013 (up from 712,000 deaths in 1990). This makes it the 10th leading cause of death worldwide.
Approximately 0.5% to 1.4% of people die by suicide, about 12 per 100,000 persons per year. Three quarters of suicides globally occur in the developing world. Rates of completed suicides are generally higher in men than in women, ranging from 1.5 times as much in the developing world to 3.5 times in the developed world. Suicide is generally most common among those over the age of 70; however, in certain countries those aged between 15 and 30 are at highest risk. There are an estimated 10 to 20 million non-fatal attempted suicides every year. Non-fatal suicide attempts may lead to injury and long-term disabilities. In the Western world, attempts are more common in young people and females.
Views on suicide have been influenced by broad existential themes such as religion, honor, and the meaning of life. The Abrahamic religions traditionally consider suicide an offense towards God due to the belief in the sanctity of life. During the samurai era in Japan, a form of suicide known as seppuku was respected as a means of making up for failure or as a form of protest. Sati, a practice outlawed by the British Raj, expected the Indian widow to kill herself on her husband's funeral fire, either willingly or under pressure from the family and society. Suicide and attempted suicide, while previously illegal, are no longer in most Western countries. It remains a criminal offense in many countries. In the 20th and 21st centuries, suicide has been used on rare occasions as a form of protest, and kamikaze and suicide bombings have been used as a military or terrorist tactic. The word is from the Latin "suicidium", which means "the killing of oneself".
Definitions.
Suicide, also known as completed suicide, is the "act of taking one's own life". Attempted suicide or non-fatal suicidal behavior is self-injury with the desire to end one's life that does not result in death. Assisted suicide is when one individual helps another bring about their own death indirectly via providing either advice or the means to the end. This is in contrast to euthanasia, where another person takes a more active role in bringing about a person's death. Suicidal ideation is thoughts of ending one's life but not taking any active efforts to do so., Gaius Nymphidius Sabinus ( c. 35 -- 68 ) was a Prefect of the Praetorian Guard during the rule of Emperor Nero from 65 until his death in 68 . He shared this office together with Gaius Ophonius Tigellinus , replacing his previous colleague Faenius Rufus . During the second half of the 60s , Nero grew increasingly unpopular with the people and the army , leading to a number of rebellions which ultimately caused his downfall and suicide in 68 . Nymphidius took part in the final conspiracy against Nero and persuaded the Praetorian Guard to desert him , but when he attempted to have himself declared emperor , he was killed by his own soldiers ., SiN is a first-person shooter video game developed by Ritual Entertainment and published by Activision in late 1998. The game was later released over Steam platform on April 5, 2006, either as a standalone product, or bundled together with its sequel, "SiN Episodes". It was also released, along with its expansion pack "" on GOG.com on January 30, 2014, DRM-free and fixed for modern hardware. It based on a modified version of the id Tech 2 engine., Rome is a city and special "comune" (named "Roma Capitale") in Italy. Rome is the capital of Italy and of the Lazio region. With 2,870,336 residents in , it is also the country's largest and most populated "comune" and fourth-most populous city in the European Union by population within city limits. The Metropolitan City of Rome has a population of 4.3 million residents. The city is located in the central-western portion of the Italian Peninsula, within Lazio (Latium), along the shores of Tiber river. The Vatican City is an independent country geographically located within the city boundaries of Rome, the only existing example of a country within a city: for this reason Rome has been often defined as capital of two states. , Claudius (1 August 10 BC  13 October 54 AD) was Roman emperor from 41 to 54. A member of the Julio-Claudian dynasty, he was the son of Drusus and Antonia Minor. He was born at Lugdunum in Gaul, the first Roman Emperor to be born outside Italy. Because he was afflicted with a limp and slight deafness due to sickness at a young age, his family ostracized him and excluded him from public office until his consulship, shared with his nephew Caligula in 37., Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand what is real. Common symptoms include false beliefs, unclear or confused thinking, hearing voices that others do not, reduced social engagement and emotional expression, and a lack of motivation. People with schizophrenia often have additional mental health problems such as anxiety disorders, major depressive illness, or substance use disorders. Symptoms typically come on gradually, begin in young adulthood, and last a long time.
The causes of schizophrenia include environmental and genetic factors. Possible environmental factors include being raised in a city, cannabis use, certain infections, parental age, and poor nutrition during pregnancy. Genetic factors include a variety of common and rare genetic variants. Diagnosis is based on observed behavior, the person's reported experiences, and reports of others familiar with the person. During diagnosis a person's culture must also be taken into account. As of 2013 there is no objective test. Schizophrenia does not imply a "split personality" or "multiple personality disorder"conditions with which it is often confused in public perception.
The mainstay of treatment is antipsychotic medication, along with counselling, job training, and social rehabilitation. It is unclear whether typical or atypical antipsychotics are better. In those who do not improve with other antipsychotics clozapine may be tried. In more serious situationswhere there is risk to self or othersinvoluntary hospitalization may be necessary, although hospital stays are now shorter and less frequent than they once were.
About 0.30.7% of people are affected by schizophrenia during their lifetimes. In 2013 there were estimated to be 23.6 million cases globally. Males are more often affected than females. About 20% of people do well, and a few recover completely. Social problems, such as long-term unemployment, poverty, and homelessness are common. The average life expectancy of people with the disorder is ten to twenty-five years less than for the general population. This is the result of increased physical health problems and a higher suicide rate (about 5%). In 2013 an estimated 16,000 people worldwide died from behavior related to, or caused by, schizophrenia., In Japanese, they are usually referred to as or . According to translator William Scott Wilson: "In Chinese, the character  was originally a verb meaning "to wait upon" or "accompany persons" in the upper ranks of society, and this is also true of the original term in Japanese, saburau. In both countries the terms were nominalized to mean "those who serve in close attendance to the nobility", the pronunciation in Japanese changing to saburai. According to Wilson, an early reference to the word "samurai" appears in the Kokin Wakash (905914), the first imperial anthology of poems, completed in the first part of the 10th century., In Ancient Rome, the Imperial Praetorian Guard or Praetorian Guard were a unit of the Imperial Roman Army formed of elite soldiers initially recruited in Italy. These units originated from the small group of men around the republican magistrates, known under the designation of praetor, and also originated from around roman legion camps where the legion commandant's main tent (Latin: "Prætorium") garrisoned when engaged in battle campaigns. The Praetorian Guard is one of the most famous military units in Roman History., India, officially the Republic of India ("Bhrat Gaarjya"), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country (with over 1.2 billion people), and the most populous democracy in the world. It is bounded by the Indian Ocean on the south, the Arabian Sea on the southwest, and the Bay of Bengal on the southeast. It shares land borders with Pakistan to the west; China, Nepal, and Bhutan to the northeast; and Myanmar (Burma) and Bangladesh to the east. In the Indian Ocean, India is in the vicinity of Sri Lanka and the Maldives. India's Andaman and Nicobar Islands share a maritime border with Thailand and Indonesia. Its capital is New Delhi; other metropolises include Mumbai, Kolkata, Chennai, Bangalore, Hyderabad and Ahmedabad., Ancient Rome was an Italic civilization that began on the Italian Peninsula as early as the 8th century BC. Located along the Mediterranean Sea and centered on the city of Rome, it expanded to become one of the largest empires in the ancient world with an estimated 50 to 90 million inhabitants (roughly 20% of the world's population) and covering 5.0 million square kilometers at its height in AD 117., , officially , abbreviated as , and used as a verb as , were suicide attacks by military aviators from the Empire of Japan against Allied naval vessels in the closing stages of the Pacific campaign of World War II, designed to destroy warships more effectively than was possible with conventional attacks. During World War II, about 3,860 "kamikaze" pilots died, and about 19% of "kamikaze" attacks managed to hit a ship., The term Julio-Claudian dynasty refers to the first five Roman emperorsAugustus, Tiberius, Caligula, Claudius, and Neroor the family to which they belonged. They ruled the Roman Empire from its formation under Augustus in the second half of the 1st century (44/31/27) BC, until AD 68 when the last of the line, Nero, committed suicide., The British Raj (from "rj", literally, "rule" in Hindustani) was the rule of the British Crown in the Indian subcontinent between 1858 and 1947. The rule is also called Crown rule in India, or direct rule in India. The region under British control was commonly called India in contemporaneous usage, and included areas directly administered by the United Kingdom, which were collectively called British India, and those ruled by indigenous rulers, but under British tutelage or paramountcy, and called the princely states. The resulting political union was also called the Indian Empire and after 1876 issued passports under that name.
As India, it was a of the League of Nations, a participating nation in the Summer Olympics in 1900, 1920, 1928, 1932, and 1936, and a founding member of the United Nations in San Francisco in 1945., The praefectus annonae ("Prefect of the Provisions") was a Roman imperial official charged with the supervision of the grain supply to the city of Rome. Under the republic, the job was usually done by an aedile. However, in emergencies, or in times of extraordinary scarcity, an individual would be elected to the office, and would take charge of supplying the entire city with provisions. L. Minucius Augurinus, the accuser of Spurius Maelius, was the first individual appointed to this office, serving from 439BC. During the early 60s BC, following the sacking of the port of Ostia by pirates, Pompey held the powers of the office. Around 7 BC, the first Roman Emperor, Augustus, followed this example, and after vesting himself with these powers, specified that two former praetors should be appointed every year to carry out the functions of this office. Augustus transferred powers from the aedile to this office, and specified that all holders of this office be members of the Equestrian order. Augustus also specified that these officers were to be aided by an "adjutor" (from the 2nd century the "subpraefectus"). Later, Augustus specified that these individuals must be of consular rank. After Augustus' reign, one individual would usually hold this office, and this continued until the fall of the Roman Empire., Julia Agrippina, most commonly referred to as Agrippina Minor or Agrippina the Younger, and after AD 50 known as Julia Augusta Agrippina ("Minor"; Latin for the "younger"; 7 November 15  19/23 March 59), was a Roman Empress and one of the more prominent women in the Julio-Claudian dynasty. She was a great-granddaughter of the Emperor Augustus, great-niece and adoptive granddaughter of the Emperor Tiberius, sister of the Emperor Caligula, niece and fourth wife of the Emperor Claudius, and mother of the Emperor Nero., Nero (Latin: "Ner Claudius Caesar Augustus Germanicus"; 15 December 37 AD  9 June 68 AD) was Roman Emperor from 54 to 68, and the last in the Julio-Claudian dynasty. Nero was adopted by his great-uncle Claudius to become his heir and successor, and acceded to the throne in 54 following Claudius' death., Bipolar disorder, also known as manic depression, is a mental disorder with periods of depression and periods of elevated mood. The elevated mood is significant and is known as mania or hypomania, depending on its severity, or whether symptoms of psychosis are present. During mania, an individual behaves or feels abnormally energetic, happy, or irritable. Individuals often make poorly thought out decisions with little regard to the consequences. The need for sleep is usually reduced during manic phases. During periods of depression, there may be crying, a negative outlook on life, and poor eye contact with others. The risk of suicide among those with the illness is high at greater than 6 percent over 20 years, while self-harm occurs in 3040 percent. Other mental health issues such as anxiety disorders and substance use disorder are commonly associated.
The causes are not clearly understood, but both environmental and genetic factors play a role. Many genes of small effect contribute to risk. Environmental factors include a history of childhood abuse, and long-term stress. The condition is divided into bipolar I disorder if there is at least one manic episode and bipolar II disorder if there are at least one hypomanic episode and one major depressive episode. In those with less severe symptoms of a prolonged duration, the condition cyclothymic disorder may be diagnosed. If due to drugs or medical problems, it is classified separately. Other conditions that may present in a similar manner include attention deficit hyperactivity disorder, personality disorders, schizophrenia, and substance use disorder as well as a number of medical conditions. Medical testing is not required for a diagnosis, though blood tests or medical imaging can be done to rule out other problems.
Treatment commonly includes psychotherapy, as well as medications such as mood stabilizers and antipsychotics. Examples of mood stabilizers that are commonly used include lithium and various anticonvulsants. Treatment in a hospital without the individual's consent may be required if a person is at risk to themselves or others but refuses treatment. Severe behavioral problems may be managed with short term antipsychotics or benzodiazepines. In periods of mania it is recommended that antidepressants be stopped. If antidepressants are used for periods of depression they should be used with a mood stabilizer. Electroconvulsive therapy (ECT) may be helpful for those who do not respond to other treatments. If treatments are stopped, it is recommended that this be done slowly. Many individuals have financial, social or work-related problems due to the illness. These difficulties occur a quarter to a third of the time on average. The risk of death from natural causes such as heart disease is twice that of the general population. This is due to poor lifestyle choices and the side effects from medications.
About 3 percent of people in the United States are estimated to have bipolar disorder at some point in their life. Lower rates of around 1 percent are found in other countries. The most common age at which symptoms begin is 25. Rates appear to be similar in females and males. The economic costs of the disorder has been estimated at $45 billion for the United States in 1991. A large proportion of this was related to a higher number of missed work days, estimated at 50 per year. People with bipolar disorder often face problems with social stigma., The conspiracy of Gaius Calpurnius Piso in AD 65 was a major turning point in the reign of the Roman emperor Nero (5468). The plot reflected the growing discontent among the ruling class of the Roman state with Nero's increasingly despotic leadership, and as a result is a significant event on the road towards his eventual suicide and the chaos of the Year of Four Emperors which followed., Italy, officially the Italian Republic, is a unitary parliamentary republic in Europe. Located in the heart of the Mediterranean Sea, Italy shares open land borders with France, Switzerland, Austria, Slovenia, San Marino and Vatican City. Italy covers an area of and has a largely temperate seasonal climate and Mediterranean climate; due to its shape, it is often referred to in Italy as "lo Stivale" (the Boot). With 61 million inhabitants, it is the fourth most populous EU member state., A crisis hotline is a phone number people can call to get immediate emergency telephone counseling, usually by trained volunteers. The first such service was founded in England in 1953 and such hotlines have existed in most major cities of the English speaking world at least since the mid-1970s. Initially set up to help those contemplating suicide, many have expanded their mandate to deal more generally with emotional crises. Similar hotlines operate to help people in other circumstances, including rape victims, bullying victims, runaway children, human trafficking victims, and people who identify as LGBT or intersex., The Roman emperor was the ruler of the Roman Empire during the imperial period (starting in 27 BC). The emperors used a variety of different titles throughout history. Often when a given Roman is described as becoming "emperor" in English, it reflects his taking of the title "Augustus" or "Caesar". Another title often used was "imperator", originally a military honorific. Early Emperors also used the title "princeps" (first citizen). Emperors frequently amassed republican titles, notably "Princeps Senatus", "Consul" and "Pontifex Maximus"., Alcoholism, also known as alcohol use disorder (AUD), is a broad term for any drinking of alcohol that results in problems. It was previously divided into two types: alcohol abuse and alcohol dependence. In a medical context, alcoholism is said to exist when two or more of the following conditions is present: a person drinks large amounts over a long time period, has difficulty cutting down, acquiring and drinking alcohol takes up a great deal of time, alcohol is strongly desired, usage results in not fulfilling responsibilities, usage results in social problems, usage results in health problems, usage results in risky situations, withdrawal occurs when stopping, and alcohol tolerance has occurred with use. Risky situations include drinking and driving or having unsafe sex among others. Alcohol use can affect all parts of the body but particularly affects the brain, heart, liver, pancreas, and immune system. This can result in mental illness, WernickeKorsakoff syndrome, an irregular heart beat, liver failure, and an increase in the risk of cancer, among other diseases. Drinking during pregnancy can cause damage to the baby resulting in fetal alcohol spectrum disorders. Generally women are more sensitive to alcohol's harmful physical and mental effects than men.
Both environmental factors and genetics are associated with alcoholism with about half the risk attributed to each. A person with a parent or sibling with alcoholism is three to four times more likely to be alcoholic themselves. Environmental factors include social, cultural, and behavioral influences. High stress levels, anxiety, as well as inexpensive easily accessible alcohol increases risk. People may continue to drink partly to prevent or improve symptoms of withdrawal. A low level of withdrawal may last for months following stopping. Medically, alcoholism is considered both a physical and mental illness. Both questionnaires and certain blood tests may detect people with possible alcoholism. Further information is then collected to confirm the diagnosis.
Prevention of alcoholism may be attempted by regulating and limiting the sale of alcohol, taxing alcohol to increase its cost, and providing inexpensive treatment. Treatment may take several steps. Because of the medical problems that can occur during withdrawal, alcohol detoxification should be carefully controlled. One common method involves the use of benzodiazepine medications, such as diazepam. This can be either given while admitted to a health care institution or occasionally while a person remains in the community with close supervision. Other addictions or mental illness may complicate treatment. After detoxification support such as group therapy or support groups are used to help keep a person from returning to drinking. One commonly used form of support is the group Alcoholics Anonymous. The medications acamprosate, disulfiram, or naltrexone may also be used to help prevent further drinking.
The World Health Organization estimates that as of 2010 there were 208 million people with alcoholism worldwide (4.1% of the population over 15 years of age). In the United States about 17 million (7%) of adults and 0.7 million (2.8%) of those age 12 to 17 years of age are affected. It is more common among males and young adults, becoming less common in middle and old age. It is the least common in Africa at 1.1% and has the highest rates in Eastern Europe at 11%. Alcoholism directly resulted in 139,000 deaths in 2013 up from 112,000 deaths in 1990. A total of 3.3 million deaths (5.9% of all deaths) are believed to be due to alcohol. It often reduces a person's life expectancy by around ten years. In the United States it resulted in economic costs of $224 billion USD in 2006. Many terms, some insulting and others informal, have been used to refer to people affected by alcoholism including: tippler, drunkard, dipsomaniac, and souse. In 1979, the World Health Organization discouraged the use of "alcoholism" due to its inexact meaning, preferring "alcohol dependence syndrome".
Signs and symptoms.
Early signs.
The risk of alcohol dependence begins at low levels of drinking and increases directly with both the volume of alcohol consumed and a pattern of drinking larger amounts on an occasion, to the point of intoxication, which is sometimes called "binge drinking". Young adults are particularly at risk of engaging in binge drinking., Germanicus (24 May 15 BC  10 October AD 19) was a member of the Julio-Claudian dynasty and a prominent general of the early Roman Empire. He was born in Rome, Italia, to Nero Claudius Drusus and his wife Antonia Minor. His original name at birth was either Nero Claudius Drusus after his father, or Tiberius Claudius Nero after his uncle, the second Roman emperor Tiberius. The agnomen "Germanicus" was added to his full name in 9 BC when it was posthumously awarded to his father in honour of his victories in Germania. By AD 4 he was adopted as Tiberius' son and heir. As a result, Germanicus was adopted out of the Claudii and into the Julii. In accordance with Roman naming conventions, he adopted the name Germanicus Julius Caesar., Subject: nymphidius sabinus, Relation: date_of_birth, Options: (A) 1 (B) 10 (C) 100 (D) 11 (E) 12 (F) 15 (G) 15 december 37 (H) 1858 (I) 19 (J) 1920 (K) 1936 (L) 1953 (M) 1998 (N) 2 (O) 20 (P) 2006 (Q) 2010 (R) 2013 (S) 23 (T) 27 (U) 3 (V) 30 (W) 31 (X) 35 (Y) 37 (Z) 4 ([) 40 (\) 400 (]) 50 (^) 6 (_) 61 (`) 62 (a) 65 (b) 68 (c) 69 (d) 7 (e) 70 (f) 712 (g) 8 (h) 842 (i) 860 (j) 870 (k) 90 (l) 905
Output: 100