Context: Russia (from the  Rus'), also officially known as the Russian Federation, is a country in Eurasia. At , Russia is the largest country in the world by surface area, covering more than one-eighth of the Earth's inhabited land area, and the ninth most populous, with over 140 million people at the end of March 2016. The European western part of the country is much more populated and urbanised than the eastern, about 77% of the population live in European Russia. Russia's capital Moscow is one of the largest cities in the world, other major urban centers include Saint Petersburg, Novosibirsk, Yekaterinburg, Nizhny Novgorod and Samara., In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from errors during DNA replication or other types of damage to DNA, which then may undergo error-prone repair (especially microhomology-mediated end joining), or cause an error during other forms of repair, or else may cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity., Saint Petersburg is Russia's second-largest city after Moscow, with five million inhabitants in 2012, and an important Russian port on the Baltic Sea. It is politically incorporated as a federal subject (a federal city). Situated on the Neva River, at the head of the Gulf of Finland on the Baltic Sea, it was founded by Tsar Peter the Great on May . In 1914, the name was changed from Saint Petersburg to Petrograd, in 1924 to Leningrad, and in 1991 back to Saint Petersburg. Between 17131728 and 17321918, Saint Petersburg was the imperial capital of Russia. In 1918, the central government bodies moved to Moscow., Haemophilia, also spelled hemophilia, is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding longer after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain. Those with mild disease may only have symptoms after an accident or during surgery. Bleeding into a joint can result in permanent damage while bleeding in the brain can result in long term headaches, seizures, or a decreased level of consciousness.
There are two main types of haemophilia: haemophilia A, which occurs due to not enough clotting factor VIII, and haemophilia B, which occurs due to not enough clotting factor IX. They are typically inherited from one's parents through an X chromosome with a nonfunctional gene. Rarely a new mutation may occur during early development or haemophilia may develop later in life due to antibodies forming against a clotting factor. Other types include haemophilia C, which occurs due to not enough factor XI, and parahaemophilia, which occurs due to not enough factor V. Acquired haemophilia is associated with cancers, autoimmune disorders, and pregnancy. Diagnosis is by testing the blood for its ability to clot and its levels of clotting factors.
Prevention may occur by removing an egg, fertilizing it, and testing the embryo before transferring it to the uterus. Treatment is by replacing the missing blood clotting factors. This may be done on a regular basis or during bleeding episodes. Replacement may take place at home or in hospital. The clotting factors are made either from human blood or by recombinant methods. Up to 20% of people develop antibodies to the clotting factors which makes treatment more difficult. The medication desmopressin may be used in those with mild haemophilia A. Studies of gene therapy are in early human trials.
Haemophilia A affects about 1 in 5,00010,000, while haemophilia B affects about 1 in 40,000, males at birth. As haemophilia A and B are X-linked recessive disorders females are very rarely severely affected. Some females with a nonfunctional gene on one of the X chromosomes may be mildly symptomatic. Haemophilia C occurs equally in both sexes and is mostly found in Ashkenazi Jews. In the 1800s haemophilia was common within the royal families of Europe. The difference between haemophilia A and B was determined in 1952. The word is from the Greek "haima"  meaning blood and "philia"  meaning love.
Signs and symptoms.
Characteristic symptoms vary with severity. In general symptoms are internal or external bleeding episodes, which are called "bleeds". People with more severe haemophilia suffer more severe and more frequent bleeds, while people with mild haemophilia usually suffer more minor symptoms except after surgery or serious trauma. In cases of moderate haemophilia symptoms are variable which manifest along a spectrum between severe and mild forms., France, officially the French Republic, is a country with territory in western Europe and several overseas regions and territories. The European, or metropolitan, area of France extends from the Mediterranean Sea to the English Channel and the North Sea, and from the Rhine to the Atlantic Ocean. Overseas France include French Guiana on the South American continent and several island territories in the Atlantic, Pacific and Indian oceans. France spans and had a total population of almost 67 million people as of January 2017. It is a unitary semi-presidential republic with the capital in Paris, the country's largest city and main cultural and commercial centre. Other major urban centres include Marseille, Lyon, Lille, Nice, Toulouse and Bordeaux., Gaul (Latin: "Gallia") was a region of Western Europe during the Iron Age that was inhabited by Celtic tribes, encompassing present day France, Luxembourg, Belgium, most of Switzerland, Northern Italy, as well as the parts of the Netherlands, Central Italy and Germany on the west bank of the Rhine. It covered an area of 190,800 mi² or 494,169 km². According to the testimony of Julius Caesar, Gaul was divided into three parts: Gallia Celtica, Belgica and Aquitania.
Archaeologically, the Gauls were bearers of the La Tène culture, which extended across all of Gaul, as well as east to Raetia, Noricum, Pannonia and southwestern Germania during the 5th to 1st centuries BC.
During the 2nd and 1st centuries BC, Gaul fell under Roman rule: Gallia Cisalpina was conquered in 203 BC and Gallia Narbonensis in 123 BC. Gaul was invaded after 120 BC by the Cimbri and the Teutons, who were in turn defeated by the Romans by 103 BC. Julius Caesar finally subdued the remaining parts of Gaul in his campaigns of 58 to 51 BC., Belgium , officially the Kingdom of Belgium, is a sovereign state in Western Europe bordered by France, the Netherlands, Germany, Luxembourg, and the North Sea. It is a small, densely populated country which covers an area of and has a population of about 11 million people. Straddling the cultural boundary between Germanic and Latin Europe, Belgium is home to two main linguistic groups: the Dutch-speaking, mostly Flemish community, which constitutes about 59% of the population, and the French-speaking, mostly Walloon population, which comprises 41% of all Belgians. Additionally, there is a small group of German-speakers who live in the East Cantons located around the High Fens area, and bordering Germany., An embryo is an early stage of development of a multicellular diploid eukaryotic organism. In general, in organisms that reproduce sexually, an embryo develops from a zygote, the single cell resulting from the fertilization of the female egg cell by the male sperm cell. The zygote possesses half the DNA of each of its two parents. In plants, animals, and some protists, the zygote will begin to divide by mitosis to produce a multicellular organism. The result of this process is an embryo., The uterus (from Latin "uterus", plural "uteri") or womb is a major female hormone-responsive reproductive sex organ of humans and most other mammals. In the human, the lower end of the uterus, the cervix, opens into the vagina, while the other end, the fundus, is connected to the fallopian tubes. It is within the uterus that the fetus develops during gestation. In the embryo the uterus develops from the paramesonephric ducts which fuse into the single organ known as a simplex uterus. The uterus has different forms in many other animals and in some it exists as two separate uteri known as a duplex uterus., French (or ) is a Romance language of the Indo-European family. It descended from the Vulgar Latin of the Roman Empire, as all Romance languages. French has evolved from Gallo-Romance, the spoken Latin in Gaul, and more specifically in Northern Gaul. Its closest relatives are the other langues d'oïllanguages historically spoken in northern France and in southern Belgium, which French (Francien) has largely supplanted. French was also influenced by native Celtic languages of Northern Roman Gaul like Gallia Belgica and by the (Germanic) Frankish language of the post-Roman Frankish invaders. Today, owing to France's past overseas expansion, there are numerous French-based creole languages, most notably Haitian Creole. A French-speaking person or nation may be referred to as "Francophone" in both English and French., Vulgar Latin or Sermo Vulgaris ("common speech") is a generic term for the "nonstandard" (as opposed to "classical") sociolects of Latin from which the Romance languages developed. Works written in Latin during classical times used Classical Latin rather than Vulgar Latin, with very few exceptions (most notably sections of Gaius Petronius' "Satyricon"). Because of its nonstandard nature, Vulgar Latin had no official orthography. Vulgar Latin is sometimes also called colloquial Latin, or Common Romance (particularly in the late stage). In Renaissance Latin, Vulgar Latin was called "vulgare Latinum" or "Latinum vulgare.", Haitian Creole is a French-based creole language spoken by 9.612million people worldwide, and the only language of most Haitians. It is a creole language based largely on 18th century French with influences from Portuguese, Spanish, English, Taíno, and West African languages. Haitian Creole emerged from contact between French settlers and African slaves during the Atlantic slave trade in the French colony of Saint-Domingue (now Haiti). Haitians are the largest creole-speaking community in the world., Faith Healer is a play by Brian Friel about the life of the faith healer Francis Hardy as monologued through the shifting memories of Hardy, his wife, Grace, and stage manager, Teddy., Pierre Gilliard ( 16 May 1879 -- 30 May 1962 ) was a Swiss academic and author , best known as the French language tutor to the five children of Emperor Nicholas II of Russia from 1905 to 1918 . In 1921 , after the Russian Revolution of 1917 , he published a memoir , Thirteen Years at the Russian Court , about his time with the family . In his memoirs , Gilliard described Tsarina Alexandra 's torment over her son 's haemophilia and her faith in the ability of starets Grigori Rasputin to heal the boy ., Grigori Yefimovich Rasputin was a Russian peasant, an experienced traveler, a mystical faith healer, and trusted friend of the family of Nicholas II, the last Tsar of the Russian Empire. He became an influential figure in Saint Petersburg, especially after August 1915 when Nicholas took command of the army fighting in World War I. Advising his wife, Alexandra Feodorovna, in countless spiritual and political issues, Rasputin became an easy scapegoat for Russian nationalists, aristocrats and liberals., Russia, also officially known as the Russian Empire, was a state that existed from 1721 until it was overthrown by the short-lived liberal February Revolution in 1917. One of the largest empires in world history, stretching over three continents, the Russian Empire was surpassed in landmass only by the British and Mongol empires. The rise of the Russian Empire happened in association with the decline of neighboring rival powers: the Swedish Empire, the PolishLithuanian Commonwealth, Persia and the Ottoman Empire. It played a major role in 181214 in defeating Napoleon's ambitions to control Europe, and expanded to the west and south., Pregnancy, also known as gravidity or gestation, is the time during which one or more offspring develops inside a woman. A multiple pregnancy involves more than one offspring, such as with twins. Pregnancy can occur by sexual intercourse or assisted reproductive technology. It usually lasts around 40 weeks from the last menstrual period (LMP) and ends in childbirth. This is just over nine lunar months, where each month is about 29 days. When measured from conception it is about 38 weeks. An embryo is the developing offspring during the first eight weeks following conception, after which, the term "fetus" is used until birth. Symptoms of early pregnancy may include missed periods, tender breasts, nausea and vomiting, hunger, and frequent urination. Pregnancy may be confirmed with a pregnancy test.
Pregnancy is typically divided into three trimesters. The first trimester is from week one through 12 and includes conception. Conception is when the sperm fertilizes the egg. The fertilized egg then travels down the fallopian tube and attaches to the inside of the uterus, where it begins to form the fetus and placenta. The first trimester carries the highest risk of miscarriage (natural death of embryo or fetus). The second trimester is from week 13 through 28. Around the middle of the second trimester, movement of the fetus may be felt. At 28 weeks, more than 90% of babies can survive outside of the uterus if provided high-quality medical care. The third trimester is from 29 weeks through 40 weeks.
Prenatal care improves pregnancy outcomes. Prenatal care may include taking extra folic acid, avoiding drugs and alcohol, regular exercise, blood tests, and regular physical examinations. Complications of pregnancy may include high blood pressure of pregnancy, gestational diabetes, iron-deficiency anemia, and severe nausea and vomiting among others. Term pregnancy is 37 to 41 weeks, with early term being 37 and 38 weeks, full term 39 and 40 weeks, and late term 41 weeks. After 41 weeks, it is known as post term. Babies born before 37 weeks are preterm and are at higher risk of health problems such as cerebral palsy. Delivery before 39 weeks by labor induction or caesarean section is not recommended unless required for other medical reasons.
About 213 million pregnancies occurred in 2012, of which, 190 million were in the developing world and 23 million were in the developed world. The number of pregnancies in women ages 15 to 44 is 133 per 1,000 women. About 10% to 15% of recognized pregnancies end in miscarriage. In 2013, complications of pregnancy resulted in 293,000 deaths, down from 377,000 deaths in 1990. Common causes include maternal bleeding, complications of abortion, high blood pressure of pregnancy, maternal sepsis, and obstructed labor. Globally, 40% of pregnancies are unplanned. Half of unplanned pregnancies are aborted. Among unintended pregnancies in the United States, 60% of the women used birth control to some extent during the month pregnancy occurred., A starets (fem. ) is an elder of a Russian Orthodox monastery who functions as venerated adviser and teacher. "Elders" or "spiritual fathers" are charismatic spiritual leaders whose wisdom stems from God as obtained from ascetic experience. It is believed that through ascetic struggle, prayer and Hesychasm (seclusion or withdrawal), the Holy Spirit bestows special gifts onto the elder including the ability to heal, prophesy, and most importantly, give effective spiritual guidance and direction. Elders are looked upon as being an inspiration to believers and an example of saintly virtue, steadfast faith, and spiritual peace., Gallia Belgica (Belgic Gaul) was a province of the Roman empire located in Belgium, in the northern and eastern parts of Roman Gaul.
It began as one of the three main provinces of Gaul (known as the "Tres Galliae" the other two being Gallia Aquitania and Gallia Lugdunensis) described by its Roman conqueror Julius Caesar. An official Roman province was later created by emperor Augustus in 22 BC., Subject: pierre gilliard, Relation: occupation, Options: (A) bank (B) commercial (C) diversity (D) emperor (E) extra (F) general (G) healer (H) major (I) manager (J) official (K) peasant (L) saint (M) slave (N) sovereign (O) teacher (P) tsar
Output: teacher