Context: The foot-and-mouth disease virus (FMDV) is the pathogen that causes foot-and-mouth disease. It is a picornavirus, the prototypical member of the "Aphthovirus" genus. The disease, which causes vesicles (blisters) in the mouth and feet of bovids, suids, ovids, caprids and other cloven-hoofed animals is highly infectious and a major plague of animal farming., In epizoology, an epizootic (from Greek: "epi-" upon + "zoon" animal) is a disease event in a nonhuman animal population, analogous to an epidemic in humans. An epizootic may be: restricted to a specific locale (an "outbreak"), general (an "epizootic") or widespread ("panzootic"). High population density is a major contributing factor to epizootics. Aquaculture is an industry sometimes plagued by disease because of the large number of fish confined to a small area., Foot-and-mouth disease or hoof-and-mouth disease (Aphthae epizooticae) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, including domestic and wild bovids. The virus causes a high fever for approximately two to six days, followed by blisters inside the mouth and on the feet that may rupture and cause lameness., A picornavirus is a virus belonging to the family "Picornaviridae", a family of viruses in the order Picornavirales. Vertebrates, including humans, serve as natural hosts. Picornaviruses are nonenveloped viruses that represent a large family of small, cytoplasmic, plus-strand RNA(~7.5kb) viruses with a 30 nm icosahedral capsid. Its genome does not have a lipid membrane. Picornaviruses are found in mammals and birds. There are currently 50 species in this family, divided among 29 genera. These include the Entero-, Aphtho-, Cardio-, Rhino- and Hepatovirus genera. The viruses in this family can cause a range of diseases including paralysis, meningitis, hepatitis and poliomyelitis. Picornaviruses are in Baltimore IV class. Their genome single-stranded (+) sense RNA is that functions as mRNA after entry into the cell and all viral mRNA synthesized is of genome polarity. The mRNA encodes RNA dependent RNA polymerase. This polymerase makes complementary minus strands of RNA and then use as template to make more plus strand. The first synthesized molecule is protein in contrast to all other viruses. So, Overview of picornavirus replication are in order to attachment, entry, translation, transcription/genome replication (one and the same process), assembly and exit., Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point. There is not a single agreed-upon upper limit for normal temperature with sources using values between . The increase in set-point triggers increased muscle contraction and causes a feeling of cold. This results in greater heat production and efforts to conserve heat. When the set-point temperature returns to normal, a person feels hot, becomes flushed, and may begin to sweat. Rarely a fever may trigger a febrile seizure. This is more common in young children. Fevers do not typically go higher than .
A fever can be caused by many medical conditions ranging from the not serious to potentially serious. This includes viral, bacterial and parasitic infections such as the common cold, urinary tract infections, meningitis, malaria and appendicitis among others. Non-infectious causes include vasculitis, deep vein thrombosis, side effects of medication, and cancer among others. It differs from hyperthermia, in that hyperthermia is an increase in body temperature over the temperature set-point, due to either too much heat production or not enough heat loss.
Treatment to reduce fever is generally not required. Treatment of associated pain and inflammation, however, may be useful and help a person rest. Medications such as ibuprofen or paracetamol may help with this as well as lower temperature. Measures such as putting a cool damp cloth on the forehead and having a slightly warm bath are not useful and may simply make a person more uncomfortable. Children younger than three months require medical attention, as might people with serious medical problems such as a compromised immune system or people with other symptoms. Hyperthermia does require treatment.
Fever is one of the most common medical signs. It is part of about 30% of healthcare visits by children and occurs in up to 75% of adults who are seriously sick. While fever is a useful defense mechanism, treating fever does not appear to worsen outcomes. Fever is viewed with greater concern by parents and healthcare professionals than it usually deserves, a phenomenon known as fever phobia., Aphthovirus ( from the Greek aphtha - , vesicles in the mouth ) is a viral genus of the family Picornaviridae . Aphthoviruses infect vertebrates , and include the causative agent of foot - and - mouth disease . Foot - and - mouth disease virus ( FMDV ) is the prototypic member of the genus Aphthovirus . There are seven FMDV serotypes : A , O , C , SAT 1 , SAT 2 , SAT 3 and Asia 1 , and four non-FMDV serotypes belonging to three additional species Bovine rhinitis A virus ( BRAV ) , Bovine rhinitis B virus ( BRBV ) and Equine rhinitis A virus ( ERAV ) ., Subject: aphthovirus, Relation: parent_taxon, Options: (A) animal (B) aphthovirus (C) area (D) cancer (E) picornavirus (F) virus
Output: picornavirus