niryuu/sni-each-converted huggingface dataset:
Here , we show that dualfunction hemagglutinin-esterase envelope proteins of nidoviruses distinguish between a variety of closely related O-Ac-Sias.
Output: purpose
The purpose of this network is to provide timely and accurate laboratory results to the Global Polio Eradication Initiative.
Output: purpose
are established infectious agents of humans and cattle , respectively.
Output: background
All samples were subjected to real-time reverse-transcription polymerase chain reaction ( RRT-PCR ) for detecting H9-Specific viral RNA.
Output: method
optimize treatment , and develop new therapeutics.
Output: finding
Nonstructural protein σ1s is implicated in cell cycle arrest and apoptosis in reovirus-infected cells but is completely dispensable for reovirus replication in cultured cells.
Output: finding
Overlapping peptides covering the entire NiV-G protein were used to identify major histocompatibility complex class I/II-restricted T cell responses in type I interferon receptor-deficient ( IFNAR − / − ) mice after vaccination with the MVA-NiV-G candidate vaccines.
Output: method
On this basis , recommendations are made to improve the control of aerosol-transmitted infections in hospitals as well as in the design and construction of future isolation facilities.
Output: purpose
On otologic examination , a few vesicles were observed in the external auditory canal of the right ear with a normal tympanic membrane.
Output: method
Polymerase chain reaction was performed for 13 respiratory pathogens.
Output: method
Clara cells are non-ciliated , secretory bronchiolar epithelial cells that serve to detoxify harmful inhaled substances.
Output: background
These should complement current efforts to block viroporin channel activity.
Output: purpose
Meanwhile , hepatitis A virus appears to be most closely related with developed land use in dense population areas.
Output: background
Here we review the nature of TMD sorting determinants and how they may dictate transmembrane protein localization and transport.
Output: purpose
A biopsy of the erosive lesions was not performed.
Output: method
we performed video-assisted thoracoscopic surgery ( VATS ) to determine the cause of the diffuse lung infiltration.
Output: method
Medication history was not associated with an increase or decrease the likelihood of the infection.
Output: finding
During infection , NS4B induces elongation of mitochondria , which physically contact CMs.
Output: finding
This paper evaluates the performances of common constant air volume ( CAV ) system and variable air volume ( VAV ) system when carbon dioxide and particles are significantly present in outdoor environment.
Output: purpose
We used a regression model to examine the impact of influenza on death rates in tropical Singapore for the period 1996-2003.
Output: background
such as intravenous immunoglobulin ( IVIG ).
Output: finding
In this paper , we review fully integrated lab-on-chip systems for blood analysis of viral infectious disease.
Output: purpose
Compared to controls , treated kittens had lower levels of a 1 - globulins and higher mean values of g-globulins and immunoglobulins.
Output: finding
These results are comparable with observations in the United States and subtropical Hong Kong.
Output: finding
Pneumatosis intestinalis can be demonstrated radiographically.
Output: background
diverse and comprehensive discussions consisting of identification and securement of resources for disaster management ; information sharing ; timely and accurate communication and coordination with relevant agencies ; networking processes that organically link disaster prevention and preparedness during non-disaster times ; response during a disaster ; recovery after a disaster ; and learning from the experience of the disaster ; are needed for effective disaster response.
Output: finding
Five laboratories participated in the RT ( seven pipelines were tested ).
Output: method
In addition , SAT05f significantly inhibit IFN-α production from purified human plasmacytoid cells ( pDCs ) stimulated by CpG ODN.
Output: finding
the shale revolution and the gradual shift towards low-carbon sources and renewables.
Output: background
and open novel perspectives for the development of heparan sulfate-targeting therapeutic approaches for these emerging infections.
Output: finding
Reovirus likely inhibits the IFN response by at least 3 virus strain-specifi c mechanisms.
Output: finding
as they harbour transcripts circumstantially excluded from the translationally active pool.
Output: background
The functionalisation of microbeads with oligonucleotides has become an indispensable technique for high-throughput aptamer selection in SELEX protocols.
Output: background
RPL4 and HPRT1 , HMBS were the two most stable reference genes for POT , and POT+N , respectively.
Output: finding
We also found that DnaG strongly binds native and in vitro transcribed rRNA and enables its polynucleotidylation by the exosome.
Output: finding
This study presents a state-of-the-art review of the use of an expert decision analysis process in land-use planning and resort type selection in particular.
Output: purpose
Both focus-forming assays and percent infection by flow cytometry revealed overlapping replication levels in two different cell types.
Output: finding
which was validated as an independent criterion of disease classification in another 92 hospitalized patients with COVID-19.
Output: finding
This chapter reviews the structural and functional aspects of ACE and ECE and will particularly focus on these enzyme homologues in invertebrates.
Output: purpose
directly or indirectly , these concepts.
Output: background
SARS-CoV 7a and human SGT interaction was identified using a two-hybrid system screen and confirmed with interaction screens in cell culture and cellular co-localization studies.
Output: method
Furthermore , the VP6 gene of HuRVC/H28/2013 / India shows the highest similarity to a recently-reported human-like porcine RVC ( PoRVC/ASM140/2013 / India , KT932963 ) from India suggesting zoonotic transmission.
Output: finding
serving a diminishing number of overseas countries and cities.
Output: background
the deer mouse ( Peromyscus maniculatus ).
Output: method
respectively , might be added.
Output: background
Additionally , it is important that reactions are chemoselective to avoid cross reactivity with functional groups of the building blocks or the protein ( e.g. , lysine residues at the surface of the protein ).
Output: background
Time-dependent state variables 58 are taken to describe the compartments of the two populations.
Output: method
We wished to evaluate the use of DFA for epidemiological studies with a long-term observation of respiratory viruses that includes both respiratory picornaviruses and hMPV.
Output: purpose
However , these exhibit substantial cytotoxicity.
Output: background
we identified potential risk factors using predictive classification tree and random forest ensemble models.
Output: finding
The predominant cell types in epithelia exposed to oxygen plus ozone were serous cells and metaplastic cells.
Output: finding
Here , we review advancements in each of these areas that show promise for increasing the immunogenicity of DNA vaccines.
Output: purpose
The APMVs presently are being considered as human vaccine vectors.
Output: background
We discuss crisis prevention and management during the first 3 months of the severe acute respiratory syndrome ( SARS ) outbreak in Singapore.
Output: purpose
who had contact with an ill camel shortly before symptom onset , died on March 26.
Output: background
as can be seen in the ongoing Ebola epidemic in West Africa.
Output: purpose
cancer classification studies , and patient stratification in drug development.
Output: purpose
Experimental evolution of 3D G64S under selection for replicative speed led to reversion and compensation of the fidelity phenotype.
Output: finding
with a particular focus on susceptibility to viral infection.
Output: background
and speculate on how they may be related.
Output: purpose
we examined the effects of GM-CSF on cytokine production by glial cells.
Output: method
Our data on the N-and O-glycosylation is strengthened by extensive manual interpretation of each glycopeptide spectra in addition to using bioinformatics tools to confirm the complexity of glycosylation in the spike protein.
Output: finding
continually sampling their local environment.
Output: background
and to provide recommendations for expanding the use of these techniques.
Output: purpose
The objectives were to determine the median infective dose ( ID 50 ) of Cryptosporidium parvum and to describe the dose-response relationship including associated clinical illness in experimentally challenged dairy calves.
Output: purpose
we collected case and control samples and performed pathological and diagnostic analyses.
Output: method
Here we comment on current advances in the application of P. pastoris for the synthesis of recombinant subunit vaccines.
Output: purpose
Here , we review the literature focusing on different SARS-CoV 3CLpro expression constructs and assays used to measure enzymatic activity.
Output: finding
and discuss evidence suggesting that IFITM3 adopts multiple membrane topologies involving at least one intramembrane domain in its antivirally active conformation.
Output: purpose
Objective.
Output: purpose
but were generally low even for diseases with great public health importance and opportunity for interventions.
Output: finding
Here we develop a Markov Chain Monte Carlo ( MCMC ) method for estimating epidemiological parameters of the 2001 outbreak for a range of simple transmission models.
Output: purpose
Here , we have characterized functionally and structurally the interaction between the DV fusion peptide and different model membranes by fluorescence and NMR.
Output: method
they have enhanced replication and virulence in mice.
Output: finding
This study investigated the 3 7.3 kb genome of eight Taiwan strains isolated from 1992 to 2007.
Output: purpose
resulting in smarter drugs that reach their target still with the original bioavailability.
Output: purpose
5c , 5f , 5h and 5i is accompanied by low cytotoxicity.
Output: finding
Reovirus activates RIG-I and IPS-1 for phosphorylation of IRF3.
Output: background
or single new virus detection episodes where HRV positive specimens could not be sequenced.
Output: finding
These large-plaque variants emerged following viral replication in several different tissues.
Output: finding
Secondary outcomes included incidence of SARS-CoV-2related acute respiratory distress syndrome ( ARDS ) and the proportion of patients requiring mechanical ventilation.
Output: method
the etiological agent of the 2003 worldwide epidemic that culminated in approximately 8,000 cases and 800 deaths.
Output: purpose
The genes of interest were directly sequenced.
Output: method
Healthcareacquired MERS infection has become a well-known characteristic of the disease and a leading means of spread.
Output: background
Second , routine HIV testing is being implemented in populations at high risk of infection.
Output: method
may cause a significant amount of pediatric respiratory disease.
Output: finding
We describe herein the structure-guided design and evaluation of a novel class of inhibitors of MERS-CoV 3CL protease that embody a piperidine moiety as a design element that is well-suited to exploiting favorable subsite binding interactions to attain optimal pharmacological activity and PK properties.
Output: purpose
research on alternative therapies for calf diarrhea is necessary.
Output: background
the investigation of natural selection is leading to new insights into the function and dysfunction of human biology.
Output: background
and explore novel ideas of representing active genomes which promise being particularly adapted to dealing with the modeling challenges posed by host-pathogen interactions.
Output: purpose
based on a random sample of the Dutch population.
Output: method
The comparison of secondary structures revealed no new structural domains in the genotypic variants.
Output: finding
To assess the viability of isolation and contact tracing to control onwards transmission from imported cases of 2019-nCoV.
Output: purpose
HR121 or 5-Helix protein could serve as specific antiviral agents.
Output: finding
S h ; infected , I h ; recovered , R h.
Output: method
The objective of this study was to test the relevance of such a model for the discovery and validation of antiviral drugs.
Output: purpose
the infection of non-avian species has been investigated.
Output: background
The feasibility study investigates the reliability of the state of the art heart rate measuring methods in realistic situations.
Output: purpose
This review attempts to identify potentially important genes that show some consistency in ( relative ) up or downregulation in key tissues between the resistant and susceptible chickens.
Output: purpose
and a significant number of reports on nosocomial and occupational outbreaks have been reported.
Output: background
resistance profile and pharmacological properties over enfuvirtide.
Output: finding
The high mutation rate of the human immunodeficiency virus type 1 ( HIV-1 ) virus is a major problem since it evades the function of antibodies and chemical inhibitors.
Output: background
non-incineration technologies will develop quickly and will soon become the main technical option.
Output: background
and platelet-derived growth factor ( PDGF ) - BB were measured on admission.
Output: method
have been identified as one of the major factors expected to constrain hospitals ' ability to deal with future outbreaks of emerging infections.
Output: background
Objectives : The purpose of this paper is to propose a PPE calculation system to help hospitals to decide their PPE stockpile.
Output: purpose
This randomized field trial was conducted on 5 commercial dairy farms in Ohio.
Output: method
Severity was evaluated on the basis of a combined assessment of the severity of infection and severity of the clinical condition of the patients.
Output: method
or disease outbreaks , in which data required for research response are only available after the start of an outbreak.
Output: background
a model coronavirus in the same genus as SARS-CoV and MERS-CoV.
Output: method
Chinese giant salamander thymus cells ( GSTC ) and Epithelioma papulosum cyprinid ( EPC ) cells.
Output: method
Here , we summarize the post-millennium ( 2000-2017 ) research on bats in China and point out trends and future directions based on neglected topics , groups , and regions.
Output: purpose
Singapore , and Hong Kong.
Output: method
There was no significant association with the other comorbidities.
Output: finding
which can lead to cell death.
Output: background
which might be an operative alleyway to thwart dysentery from the world.
Output: finding
Here we review how SARS-Cov2 affects the eye and discuss implications for ophthalmologists.
Output: purpose
The recent development of measles vaccine-based vectored vaccine candidates has been reviewed and some information on recombinant measles vaccines expressing respiratory syncytial virus proteins has been shown and discussed.
Output: purpose
The electrical conductivity of DNAs were measured using scanning tunneling spectroscopy ( STS ) at the molecular scale and cyclic voltammetry ( CV ) technique based on the reduction of Ag + ion.
Output: finding
lung transplantation and thought to represent chronic rejection.
Output: background
Here we propose and validate a new methodology for the partition of large-scale phylogenies and the inference of transmission clusters.
Output: purpose
However , it remains unknown how the dimer structure maintains an active monomer conformation.
Output: background
with a particular emphasis on pulmonary injury and disease.
Output: background
147 human homologues , possible functional genes and 36 pseudo/unidentified genes ) by GENSCAN and BLASTN , BLASTP RepeatMasker programs.
Output: background
and form the substance of a new WHO IPC guideline.
Output: finding
There is even less understanding of the relative robustness of these methods with respect to partial information.
Output: background
However , the accuracy of procalcitonin to discriminate between viral and bacterial pneumonia requires further dissection.
Output: background
other than those found in the literature.
Output: method
By this model definition , we are able to detect the beginning of each bubble period even before it bursts.
Output: background
3C-like protease ( 3CL pro ) plays pivotal roles in the life cycle of severe acute respiratory syndrome coronavirus ( SARS-CoV ) and only the dimeric protease is proposed as the functional form.
Output: background
A standardized score was used to quantify symptom severity.
Output: method
and ( 5 ) that involve pathogens that can be easily spread to wildlife populations.
Output: finding
while too weak immune responses might cause viral persistence.
Output: background
phylogenesis and pathogenicity of the PHEV/2008 strain.
Output: purpose
Visiting time The complex patterns of individuals arriving at and leaving a location are not considered.
Output: method
By pulse-chase labeling experiments in the presence of drugs which inhibit Nlinked oligosaccharide addition and processing we demonstrate that addition of high mannose precursor oligosaccharides is necessary for transport and cleavage of the viral GP-C glycoprotein.
Output: background
and on Day 10 , when sinusitis was diagnosed.
Output: method
Viral propagation was strictly limited to the neurons and to an established line ofneuroblastoma cells in in-vivo and in-vitro experiments.
Output: method
and healthcareacquired infections among patients and from patients to healthcare workers.
Output: background
This study investigates property securities bubbles and crashes by using a dynamic mathematical methodology developed from the previous research ( Watanabe et al. 2007a , b ( 31,32 ) ).
Output: purpose
This article expands on recent findings about bats and viruses and their relevance to human infections.
Output: purpose
a betacoronavirus in the same genus as the medically important SARS-CoV and MERS-CoV.
Output: method
Here we use the available evidence to evaluate the effectiveness of exit and entry screening for detecting travellers with 2019-nCoV.
Output: finding
leading to the design and implementation of surveillance systems.
Output: background
This article discusses several conditions that are distinct entities but share the common thread of abnormal lung parenchyma that regularly leads to patient referral for surgical consideration.
Output: purpose
China , Indonesia , Taiwan and the Philippines.
Output: background
To this end we make recommendations about the information that should accompany faecal and other samples submitted to the laboratory from outbreaks of gastroenteritis.
Output: finding
Conclusion : On-site vaccination arrangements improved influenza vaccination rate among hospital employees.
Output: finding
This paper assesses the impact of the September 11 terrorist attacks and its after-effects on U.S. airline demand.
Output: purpose
Such analysis using GFP that precedes stable plant transformation will enable the rapid screening of multiple constructs to attain optimal recombinant protein expression.
Output: method
which frequently do not respond to broad-spectrum antibacterial therapy.
Output: finding
both of which reduced viral replication.
Output: finding
In addition , treatment of EV71-infected iDCs with SP600125 and SB203580 could inhibit secretions of IL-6 , IL-10 and TNF-α.
Output: finding
the parameters used for DCL generation will affect the equilibrium composition and amplification factors.
Output: finding
including cancers , particularly in immune-suppressed hosts.
Output: background
There was a significant weight loss in KO mice at Day 2 and significantly higher disease scores during the 7 days of observation.
Output: method
especially those in plasma/serum specimens.
Output: purpose
This review focuses on pathophysiology of stable and exacerbated COPD.
Output: purpose
2012 , in Jeddah , Saudi Arabia.
Output: background
-5 , and -8 genes and IFN signaling as the most significantly impacted pathways.
Output: finding
Recently several of the lead-like compounds proposed by us were reported as being active in the literature.
Output: finding
and PPV of 2.8 %.
Output: finding
a human herpesvirus , specifically interacts with Nmi.
Output: purpose
Results : The results revealed that K-601 reduced the level of inflammations in both antiinflammatory models in a dose-dependent manner.
Output: finding
Fecal samples were collected from both donor and recipient prior to each FMT and from recipients 24 hours following the last FMT.
Output: method
Live attenuated recombinant measles vaccine virus ( MV ) Edmonston-Zagreb ( EZ ) strain was evaluated as a viral vector to express the ectodomains of fusion protein of respiratory syncytial virus ( RSV F ) or glycoprotein 350 of Epstein-Barr virus ( EBV gp350 ) as candidate vaccines for prophylaxis of RSV and EBV.
Output: method
additional subjects were immunized with a single dose of 15 g VLP vaccine ( N = 2537 ) or placebo ( N = 1011 ) and assessed for safety in Part B. Results showed the H1N1 2009 VLP vaccine was safe and well-tolerated.
Output: method
It was revealed that both the N-and C-termini of the SARS-CoV E protein are exposed to the cytoplasmic side of the membranes ( N cyto C cyto ).
Output: finding
These data demonstrate the intracellular protective role of this bacterial surface polysaccharide against autophagy.
Output: finding
along with 586 time course readings from aircraft.
Output: method
The Cyprinus herpesvirus 3 ( CyHV-3 ) is a member of the new Alloherpesviridae virus family in the Herpesvirales order.
Output: background
Chickens were challenged with Eimeria maxima oocysts and 7 days post-challenge body weight gains and gross and microscopic lesions were recorded to evaluate protection levels for the different vaccine applications.
Output: finding
Transgene integration and expression of the PEDV spike protein 1 gene were confirmed by genomic PCR and RT-PCR and western blot analysis of transgenic Lemna , respectively.
Output: method
Knowledge of the survival characteristics of the virus is essential for formulating appropriate infectioncontrol measures.
Output: background
None of the children in this study were known to have any immunosuppressive conditions.
Output: method
mortality and health care costs associated with asthma.
Output: background
Sixteen of these 27 specimens ( 59 % ) contained picornaviruses ; of these 9 ( 57 % ) contained RNA of a recently discovered clade of rhinoviruses.
Output: finding
The power of molecular biology and bioinformatics has enabled the complete decoding of the viral genome within weeks.
Output: background
providing timely treatment , and differentiating the infected cases from the healthy , thus preventing further epidemics.
Output: background
and we investigated the psychological effects on hospital nurses associated with their experiences during the disaster.
Output: purpose
complete data were analyzed for 3154 to assess factors that are independently associated with MERS-CoV infection.
Output: finding
In coronaviruses , the receptor binding domain ( RBD ) in the distal part of S1 subunit of SARS-CoV-2 spike protein can directly bind to angiotensin converting enzyme 2 ( ACE2 ).
Output: background
At the same time a survey of the methods generally used for the evaluation of antioxidant activity and some of the mechanisms involved in the anti-inflammatory activities of essential oils are also reported.
Output: purpose
This will provide valuable information to researchers who are deciding whether to use hamsters as an animal model.
Output: purpose
focusing on specific applications and limitations of each vaccine category.
Output: purpose
an acute phase protein , was associated with worse outcome in lung transplant patients.
Output: background
and focal aggregates of adherent necrotic cells were present.
Output: finding
Here , the immunogenicity of a novel antigenic domain found on the carboxy-terminal of the spike protein characterized by the peptide motif GPRLQPY , was evaluated.
Output: method
Gm15441 LSL mice were treated with a PPARA agonist or fasted to assess how loss of Gm15441 impacts hepatic inflammasome activation in response to both pharmacological and physiologically-induced metabolic stress.
Output: finding
Previously obtained sequence data of the spike gene of IBV QX-like and Massachusetts strains were subjected to bioinformatics analysis.
Output: background
but with a timevarying , largely damping , transmission rate.
Output: purpose
protect against , control - and provide a public health response to - international spread of disease.
Output: purpose
Aim of the study : To investigate the effect and mechanism of BHT in the prevention of lipopolysaccharide ( LPS ) fever in manners of immune modulation.
Output: purpose
This study compared standard care with care delivered using a mobility protocol.
Output: purpose
particularly their correlation with the information environment.
Output: purpose
Discuss the definitions of terrorism and weapons of mass destruction and their relation to the illicit use of biological agents.
Output: purpose
to monitor the activity of HAV 3C pro in human embryonic kidney cells ( HEK-293T ).
Output: method
and two reviewers independently reviewed full texts.
Output: method
the primary objective was to estimate the effectiveness of influenza vaccines using a cohort design for comparison with studies using the testnegative design ( TND ).
Output: purpose
An alternate model is discussed.
Output: finding
In this chapter , we present an overview of statistical mechanical models for RNA folding and then focus on a recently developed RNA statistical mechanical model -- the Vfold model.
Output: purpose
In the study group , a BPA alerted providers of the diagnostic results suggesting viral infection and prompted them to reassess the need for antibiotics.
Output: method
We further summarized reported viromes of common farm animals in order to translate these efforts as background virus diversity profiles of common farm animals to guide preparedness of diseases at the livestock-human interface.
Output: finding
The median lung `` total severity score '' of chest CT was 6.
Output: finding
A specific BCoV-RT-PCR assay was used to detect BCoV in fecal samples.
Output: method
The spike protein of Porcine epidemic diarrhea virus is the main surface glycoprotein involved in virus attachment and entry and therefore is the target of neutralizing antibodies.
Output: background
We examine rotavirus infection in the Maradi area in southern Niger using hospital surveillance data provided by Epicentre collected over two years.
Output: purpose
The `` failure of passive transfer '' ( FPT ) group had significantly lower IgG1 Abs to BCoV than the `` acceptable passive transfer '' ( APT ) group of calves ( log10 1.98 vs. 3.38 respectively ) ( p < 0.0001 ).
Output: finding
Methods employed for Q-PCR assay validation as required in ICH Topic Q2A Ž.
Output: method
Aged rats underwent a unilateral distal permanent middle cerebral artery occlusion and one week later were treated with an anti-Nogo-A or control antibody.
Output: method
Tokyo , Japan ) or the same milk replacer with no prebiotic ( control ).
Output: method
and adopts the stochastic differential game theory to discuss this issue.
Output: purpose
NCP severity , and underlying comorbidities were the risk factors for cardiac abnormalities in COVID-19 patients.
Output: finding
Carefully calibrated transmission models have the potential to guide public health officials on the nature and scale of the interventions required to control epidemics.
Output: background
non-Hispanic and 39 % were Hispanic.
Output: finding
Efforts are underway to establish domestic and international handling guidelines and to recommend suitable quarantine conditions to facilitate embryo importation.
Output: purpose
The Shortest Common Supersequence Problem asks to obtain a shortest string that is a supersequence of every member of a given set of strings.
Output: background
The interferon-induced transmembrane protein 3 ( IFITM3 ) is a widely expressed potent antiviral effector of the host innate immune system.
Output: background
SpyTag ( A ) , and SpyCatcher ( B ).
Output: background
while QX-like isolates did not have the Ser534 site.
Output: finding
four-arm elastin-like star proteins demonstrate remarkable tolerance against trypsin digestion.
Output: finding
We suggest a mode which is droplet combining with aerosol mode.
Output: finding
measles and chickenpox , the concept of aerosol transmission is so well accepted that isolation of such patients is the norm.
Output: background
Following testing rats were sacrificed and brains processed for the Golgi-Cox method.
Output: method
Murine models are not clear on the role for B cells and antibodies in pathogenesis.
Output: background
Episodes were defined `` asymptomatic '' if no symptoms of any respiratory tract illness were present between 1 week before and 1 week after sampling.
Output: method
particularly those of human pathogens.
Output: background
although the exact mode of transmission is unknown.
Output: background
The objective of this study was to determine the role of XB130 in lipopolysaccharide ( LPS ) - induced septic responses and acute lung injury.
Output: purpose
In vivo this was associated with an increased number of alveolar macrophages and neutrophils in the lungs of IAV infected mice.
Output: finding
Consequently , it is of interest to better understand the role of T cells in vaccine-induced protection against NiV.
Output: purpose
We then address several AECB-specific issues that must be considered in cost-effectiveness analyses of AECB antimicrobial interventions.
Output: purpose
suggesting that education about the health risks of radiation exposure is important for health-care professionals.
Output: finding
Methods : Our study included 800 upper respiratory tract specimens of which 400 negative and 400 positive for viral detection in multiplex PCR.
Output: method
This study intended to investigate the utilization of Chinese medicine ( CM ) for respiratory symptoms by patients with a medical history of TB in Taiwan.
Output: purpose
Furthermore , the in vivo study showed that pentoxifylline at a concentration of 100 mg/kg and 200 mg/kg body weight was able to protect completely mice challenged with 50 × 50 % lethal dose ( LD 50 ) of JEV.
Output: finding
we give an overview of advances in research on the coronavirus fusion peptide with an emphasis on its role and properties within the biological context of host cell entry.
Output: purpose
Histopathologic examination of the brain tissue was performed using the methods of immunohistochemistry analysis and double immunofluorescence staining.
Output: method
and serum were collected as appropriate for diagnoses.
Output: method
The objective of this paper is to quantify the development of the rural electricity market at county level and below in China.
Output: purpose
In this paper , we specify a general stochastic SIR epidemic model and prove that the mean generation interval decreases when susceptible persons are at risk of infectious contact from multiple sources.
Output: purpose
HIVinfected patients may be predisposed to these viral infections due to immunodeficiency or to risk factors common to HIV and other viruses.
Output: background
we quantified the effects of all single mutations and double mutations between all positions in the IgG-binding domain of protein G ( GB1 ).
Output: method
it is critical to understand the mechanisms underlying immunocompetence in this reservoir host.
Output: purpose
Chemicals were from Roche , Sigma , or Merck.
Output: method
In this article , the physiological and biochemical characteristics of the brown pigment in commercial brown-egg layers are reviewed in relation to its various functions in the poultry industry.
Output: purpose
nor attenuated its anti-HIV-1 activity.
Output: finding
Partial nucleotide sequences of the S1 spike gene was determined from the PEDV-positive samples and compared with S1 sequences from other countries.
Output: method
comprising a 5 ′ terminal cap structure and a 3 ′ poly A tail.
Output: finding
the RdRp resides in a replicase subunit that is unusually large.
Output: background
to prevent shifts in equilibria due to precipitation.
Output: background
The full-length pDC-SIGN cDNA encodes a type II transmembrane protein of 240 amino acids.
Output: method
implicating subtle differences between ferret and human IL-2 when initiating biological functions.
Output: finding
and a clear outline of the kinds of evidence that would give proof to controversial claims.
Output: finding
A daily tick-box diary captured predefined respiratory symptoms from birth until their second birthday.
Output: method
particularly the coal combustion fly particles which may be possible virus carrier.
Output: finding
A national control program against bovine respiratory syncytial virus ( BRSV ) and bovine coronavirus ( BCV ) was launched in Norway in 2016.
Output: background
Admissionrelated electronic medical records were reviewed in entirety.
Output: method
Primary structure data showed difference in the physical properties and hydrophobic nature of both genotypes.
Output: finding
for patients with severe pneumonia.
Output: finding
a SARS-CoV was engineered including two tags associated to the E protein.
Output: background
were identified using semi-nested polymerase chain reaction ( PCR ) assays and one-step PCR assays , respectively.
Output: method
52 °C for 15 seconds and 72 °C for 30 seconds and terminal elongation at 72 °C for 5 min.
Output: method
with a random distribution ( 68 % ).
Output: finding
which was inspired by such viruses.
Output: purpose
1,2 Most of these reversible reactions take place in water , which makes them biocompatible.
Output: background
Neuropathological examination showed a marked inflammatory reaction in the cerebral leptomeninges and the grey matter of the brain.
Output: background
have also been investigated , in an attempt to clarify the essential molecular features of the interactions involving the tryptophan residues.
Output: method
We have shown that Tat activates GFAP expression in astrocytes ( Zhou , et al. , Mol.
Output: background
Here , we predict whether a virus can infect humans directly from next-generation sequencing reads.
Output: purpose
Infection control measures may have prevented nosocomial transmission of the virus.
Output: finding
were identified by checking the hospitals ' administrative databases.
Output: method
ATA binds to the essential Cys403 and Arg409 residues in the active site and has a stronger binding affinity than the natural substrate ( pTyr ).
Output: finding
To date , 114 human cases of MERS-CoV have been reported , with 54 fatalities.
Output: background
Further domain swapping experiments uncovered additional speckle-inducing and - suppressive elements in nsp15s of SARS-CoV and TGEV.
Output: finding
which motivates research into broadly-acting antivirals that can provide a greater genetic barrier to resistance.
Output: background
we have expressed a recombinant S1 protein of the SARS-CoV in transformed tobacco.
Output: purpose
cellular growth , and blood pressure control.
Output: background
New data on bat ectoparasites from Mindoro Island , Philippines are reported.
Output: purpose
We also found possible index cases among children < 5 years old in the same household for 29.0 % ( 18 of 62 ) of young infants with RSV-ARI.
Output: finding
Most peptide inhibitors that target specific amyloidogenic proteins rely heavily on sequence recognition to ensure that the inhibitory peptide is able to bind its target.
Output: background
The joining of the non-contiguous leader ' and ` body ' sequences presumably occurs during minus-strand synthesis.
Output: method
The purpose of this paper is to examine the relationships between the emergent concept of fear of expatriation with further workplace fears ( economic crisis and dangerous working conditions ) and with mental health problems.
Output: purpose
reproductive , and glandular tissues of 12/12 ( 100 % ) rats.
Output: finding
Within these systems , monoclonal aptamer microbeads can be individually generated and assayed to assess aptamer candidate fitness thereby helping eliminate stochastic effects which are common to classical SELEX techniques.
Output: background
western blot assay , and flow cytometry assay.
Output: method
Calves were fed milk replacer containing 24 % crude protein and 18 % fat.
Output: method
Targeted recombination was used to introduce amino acid substitutions into the cleavage signal of the fusion glycoprotein ( spike or S protein ) of MHV strain A59.
Output: method
Finally , IELAGTLTL was shown to have the highest population coverage ( 83.86 % ) among the whole world population.
Output: finding
laboratory-confirmed COVID-19 was reported in 12 patients.
Output: method
and the epidemiological map is changing rapidly.
Output: background
and a low incidence in age groups above 12 months ( 3.45 % ).
Output: finding
most likely by disrupting IRF9 function as part of the heterotrimeric transcription factor complex , ISGF3.
Output: finding
the causative agent of Chagas ' disease.
Output: background
Bronchiolitis was diagnosed , and the patient did not receive antibiotics.
Output: finding
We report the first case of transmission of Panton-Valentine leukocidin-producing Staphylococcus aureus to a physician during the resuscitation of an infant with fatal pneumonia.
Output: background
was used for the generation of MVA-NiV-G candidate vaccines expressing different versions of recombinant NiV-G.
Output: method
We investigated the inhibitory effect of phosphorodiamidiate morpholino oligomers ( PMOs ) targeted against norovirus sequences.
Output: purpose
Every enrolled child had a nasopharyngeal aspirate ( NPA ) sample taken.
Output: method
The high binding site plasticity is a major challenge in computational drug discovery/design efforts.
Output: background
whereas overexpression of a dominant inactive form of CRTC1 inhibited HBV transcription.
Output: finding
We looked at several investigations into the mental health of nurses after a nuclear disaster and in other situations.
Output: method
designated NC98 , isolated from the bursa of birds exhibiting poult enteritis and mortality syndrome was determined.
Output: method
We proposed that the potent inhibitory properties of ATA are a result of its strong binding in the YopH active site and in situ generation of hydrogen peroxide near catalytic cysteine residue.
Output: finding
employs multiple passive and active mechanisms to avoid induction of the antiviral type I interferons in tissue cells.
Output: background
The coil-3 10 - helix conformational transition of the Ser139-Leu141 loop serves as an enzyme activity switch.
Output: finding
C-reactive protein level , and chest radiograph were used as the parameters for the evaluation.
Output: method
and the IgG1 subclass antibody is predominant.
Output: finding
to five subtypes of influenza virus A neuraminidase ( FluV-A NA ) were investigated in the context of aqueous solution by using molecular docking and molecular dynamics studies.
Output: method
sites of ER-mitochondria interface critical for innate immune signaling.
Output: finding
many health care systems will implement a triage system that would potentially deny critical care treatment to some seriously ill patients.
Output: background
Here we report a pseudovirus neutralization assay for rapid screening of neutralizing mAbs targeting hemagglutinin ( HA ) of H5N1 and H1N1 IAV.
Output: purpose
Phenotype-based methods One of the oldest but still very important methods in clinical bacteriology is the detection of human pathogens by direct microscopic examination of the specimen.
Output: background
2020 to February 28 , 2020 were collected and retrospectively analyzed.
Output: method
Identity ( ID ) badges and lanyards worn by pediatric health care workers ( HCWs ) have been shown to be potential vectors of nosocomial bacterial infections.
Output: background
There are two forms of this complex : TRAPP I and TRAPP II.
Output: background
on the basis of the binding motifs in their active sites.
Output: finding
We propose that medRNA is spliced in trans to de-novo-initiated transcripts of protein-coding genes.
Output: purpose
We propose that CD151 organizes viral entry platforms with different types of integrin clusters for different functionalities.
Output: purpose
44 % of the 15,558 liver-expressed lncRNAs are considered novel ( Melia and Waxman , 2019 ).
Output: finding
Campylobacter , Clostridiurn difficile , rotavirus , Norwalk virus and Cryptosporidium.
Output: finding
This investigation further compared the FFD-Markov-chain model with the CFD-Eulerian model and CFD-Lagrangian model in terms of accuracy and efficiency.
Output: method
We also discuss the functional consequences of the activities of these proteases on mammalian physiology and disease.
Output: purpose
the battle against viruses has never ceased.
Output: background
• Coronavirus can cause severe immune thrombocytopenic purpura ( ITP ).
Output: finding
The purpose of this study was to generate mortality estimates among SARI patients that include deaths occurring shortly after hospital discharge and identify risk factors for mortality.
Output: purpose
with a view to standardizing concepts and measurements to enable future research to generate a cumulative knowledge base for policy and practice.
Output: purpose
Viral excretion peaked at 4 dpi and decreased to zero by 10 dpi.
Output: method
we have performed RNA sequencing of viral genomic RNA to determine the precise sites of recombination in a series of recombinants which have crossovers within the gene encoding the peplomer protein.
Output: method
This review gives an overview of the advances of thread-based microfluidic diagnostic devices in a variety of applications.
Output: purpose
based on the latest evidence published in the literature.
Output: purpose
including health professionals , due to adverse health outcomes after a severe disaster.
Output: background
In infancy , respiratory syncytial virus infection can induce bronchiolitis and set up recurrent wheezing over the next few years.
Output: finding
Therefore , the purpose of the research was to evaluate the prevalence of feline hemotropic mycoplasmas and to characterize risk factors and clinical findings associated with these infections in a cat population from the Madrid area , Spain.
Output: purpose
We found that some types of unusual viral RNA species were produced by infections with IFN-β-inducing viruses and accumulated into distinct cytoplasmic structures in an RNA-type-dependent manner.
Output: finding
glycosylation , and transport of the lymphocytic choriomeningitis virus ( LCMV ) glycoproteins have been examined.
Output: background
The physician exhibited numerous furuncles.
Output: background
In this report , we study the membrane topology of the SARS-CoV E protein by immunofluorescent staining of cells differentially permeabilized with detergents and proteinase K protection assay.
Output: purpose
sampled from 1988 to 2014.
Output: purpose
that considerably guide viral replication after host infection in an orchestrated manner.
Output: purpose
some of them frequently observed in IFN-treated patients.
Output: background
climate and land use changes.
Output: purpose
Supernatants of immortalized B cell clones containing monoclonal antibodies were screened for binding to HA proteins representing two different HA subtypes.
Output: method
demonstrating the significant differences in model outcomes.
Output: method
We consider the requirements for a standardized conceptual framework for future research capable of informing policy to reduce the morbidity and mortality impacts of such incidents.
Output: purpose
A review of the literature suggests that effective control of hospital outbreaks was accomplished in most instances by the application of proper infection control procedures.
Output: finding
high efficiency , and low toxicity.
Output: background
This chapter focuses on variabilities amongst the spike ( S ) proteins of infecting virus strains.
Output: purpose
Escherichia coli maltose binding protein ( MBP ) is employed as an N-terminal tag to increase the yield and solubility of its fusion partners.
Output: method
as well as guidelines on the diagnosis and management of CRV infections in patients intensively treated for hematological malignancies.
Output: purpose
parvovirus , rubella and measles.
Output: background
guanylyltransferase ( GTase ) and methylase activities were analysed by a series of in vitro biochemical assays using recombinant mutant proteins ; subsequently their effects on virus replication were assessed by introducing the same mutations in replicating viral genome using a reverse genetics system.
Output: method
B12 , B15 and B19 haplotypes.
Output: method
Here , we identified several nuclear factors from the cortex of control and OC43-infected mice which bind a fragment of the proximal ApoD promoter in vitro.
Output: purpose
and every other adjacent house starting from the social center was marked and respondents were interviewed using structured questionnaires.
Output: method
A 4-month-old boy was admitted to the pediatric ward of Saint-Vincent-de-Paul hospital ( Paris ) with a history of 3 days of cough and 1 day of moderate fever.
Output: finding
which included 29 1st RSV-ARI and 31 2nd RSV-ARI.
Output: finding
We report the structure of Machupo virus ( MACV ) GP1 bound with human TfR1.
Output: purpose
it is important to understand how acute exacerbations evolve.
Output: background
We assessed the emergency response of health care workers ( HCWs ) involved in case management.
Output: purpose
multiplexed detection of unlabelled nucleic acids in solution.
Output: purpose
cell apoptosis , and interferon ( IFN ) signalling was studied by flow cytometric analysis and quantitative RT - ( q ) PCR using shBCN1-MDBK cells.
Output: method
Pathogens were detected by multiplex reverse transcription polymerase chain reaction.
Output: method
They are too effort intensive for stakeholders.
Output: background
we investigated how body TRS activity affected sg RNA synthesis from neighboring body TRSs.
Output: purpose
Staffing patterns and nurses ' working conditions are risk factors for healthcare-associated infections as well as occupational injuries and infections.
Output: background
which has a strong inhibitory effect on dsRNA-induced IFN-b production.
Output: method
In this study , we have dissected the effects of PI3K-Akt-mTOR signaling pathway on rotavirus infection using both conventional cell culture models and a 3D model of human primary intestinal organoids.
Output: finding
virtual drug screening and high-throughput screening to 35 identify new drug leads that target the COVID-19 virus main protease ( M pro ).
Output: method
hypoxiainduced pulmonary vasoconstriction is accompanied by an increase instead of a decrease in NO release.
Output: finding
Longitudinal sections revealed that at nodes of Ranvier PNS-type myelin sheaths were apposed by either intact or newly formed CNS-type myelin sheaths.
Output: finding
We employed population flow data from different sources between Wuhan and other cities/regions by 23 January 2020.
Output: method
The biological implications of these findings for the MPA-mediated inhibition of members of the covalent nucleotidyl superfamily are discussed.
Output: finding
an etiological agent for many of these illnesses is rarely identified.
Output: background
These results revealed new insights on rotavirus-host interactions and provided new avenues for antiviral drug development.
Output: finding
Descriptive statistics were used to report demographic data.
Output: method
B , O and Rh ( D ) blood groups and WNV clinical disease outcome.
Output: method
Note : this report is a pre-print and has not yet been peer-reviewed.
Output: background
Objectives : To explore the epidemiological and clinical factors predictive of the case fatality rate ( CFR ) of Middle East respiratory syndrome-coronavirus ( MERS-CoV ) infection in an outbreak in Daejeon , the Republic of Korea.
Output: purpose
18-64 years of age , during the H1N1 2009 pandemic in Mexico.
Output: purpose
A cross-sectional survey among Malaysian Hajj and Umrah pilgrims in 2018.
Output: purpose