niryuu/sni-each-converted huggingface dataset:
We investigated the diagnostic and prognostic utility of plasma PENK in comparison with neutrophil gelatinase-associated lipocalin ( NGAL ) and estimated glomerular filtration rates ( eGFR ) in septic patients.
Output: purpose
and B6C3F1/N mice were assigned to control ( unenriched ) and enriched experimental groups.
Output: method
Current antibody drugs have increasingly fewer adverse effects due to their high specificity.
Output: background
( i ) Nasal swabs were tested using rapid influenza diagnostic test ( RIDT ) and two RT-PCR assays.
Output: method
and updated periodically with new probabilities every three months.
Output: method
disinfected and then homogenized for testing.
Output: method
The ellagitannin Lagerstroemin was identified as an effective component of the banaba extract responsible for the activity.
Output: background
Postweaning average daily gain and carcass characteristics were similar for ACD and RES calves.
Output: finding
Here we describe a new concept using combinatorial self-assembly of DNA nanotiles into micrometer-sized two-dimensional arrays that carry nucleic acid probes and barcoded fluorescent dyes to achieve multiplexed detection.
Output: purpose
but not the protective antiviral responses.
Output: finding
no virus particles were detected.
Output: finding
the USA , and Asia in people who travelled from the Middle East or their contacts.
Output: background
All seem to use a copy-choice template switching action for recombination.
Output: finding
Methods We actively surveyed arriving travellers at all 272 international entry-exit ports in mainland China.
Output: method
In 2006 assays for respiratory picornaviruses and hMPV were added.
Output: method
We developed a novel concept that allows to considerably improve the performance of conventionally used ÿltering-facepiece respirators against ÿne and ultraÿne aerosols including airborne viral and bacterial agents.
Output: purpose
The National Interagency Confederation for Biological Research and collaborators rapidly produced and then evaluated anti-Ebola virus IgG immunoglobulins ( collectively termed SAB-139 ) purified from Tc-bovine plasma after sequential hyperimmunization with an Ebola virus Makona isolate glycoprotein nanoparticle vaccine.
Output: background
In this study , we report the complete genome sequence of two contemporary human coronavirus OC43 ( HCoV-OC43 ) strains detected in 2003 and 2004 , respectively.
Output: purpose
Escherichia coli strain DH5α was used to amplify plasmid DNA.
Output: method
our findings indicate the potential of COVID-19 to cause greater outbreak on the ship.
Output: finding
In the present study , we used the idea of adaptive memory to understand whether human memory evolved to recall information about medicinal plants for the treatment of serious diseases.
Output: purpose
Multivariate Cox modeling was employed to assess the impact of CARV isolation on progression to CLAD and graft loss.
Output: method
and ( iii ) the use of bispecific adapters to mediate targeting of a virus to a specified moiety on a tumor cell.
Output: method
parainfluenza virus type 3 and cytomegalovirus.
Output: purpose
However , little is known about JNK1/2 and p38 MAPK signaling pathways in enterovirus 71 ( EV71 ) - infected immature dendritic cells ( iDCs ).
Output: background
focusing on the targeted , self-assembled nanoparticles which show potential to become a useful and efficient tool in cancer therapy.
Output: purpose
the full spectrum of cases is described.
Output: method
and 13 C-Met labeling was performed to quickly assess cruzain-ligand interactions for a set of eight low molecular weight compounds exhibiting micromolar binding or inhibition.
Output: method
We conducted an investigation of healthcare workers exposed to laboratory-confirmed SARS patients in the United States to evaluate infection-control practices and possible SARSassociated coronavirus ( SARS-CoV ) transmission.
Output: purpose
In this study , we further examined the relationship between Tat and Egr-1 in astrocytes.
Output: purpose
hospital with pneumonia had evidence of recent B. pertussis infection.
Output: background
The cleavage mechanism of severe acute respiratory syndrome ( SARS ) coronavirus main proteinase ( M pro or 3CL pro ) for the octapeptide AVLQSGFR is studied using molecular mechanics ( MM ) and quantum mechanics ( QM ).
Output: background
encoding thioredoxin interacting protein ( TXNIP ).
Output: background
A substantial proportion of hitherto unexplained respiratory tract illnesses is associated with human metapneumovirus ( hMPV ) infection.
Output: background
and the factors influencing their use of these protective practices.
Output: purpose
comparable endpoint titers , and similar focus staining.
Output: method
Finally , the biosafety measures required to protect researchers and clinical lab workers are considered.
Output: purpose
We describe the isolation , biological and genetic characterization of a host-range variant of bovine coronavirus ( BCoV ) detected in water buffalo ( Bubalus bubalis ).
Output: purpose
Of great value is information provided by ESCCAP ( www.esccap.org ) with information for European countries ( veterinarians and pet-owners ) on prevalences and prevention of parasitic infections in dogs and cats in the major languages of Europe.
Output: background
At present , it is of utmost 31 importance to understand the virus biology and to rapidly assess the potential of existing drugs 32 and develop new active compounds.
Output: background
are present in milk and colostrum of all lactating species.
Output: background
while maintaining the attenuated phenotype.
Output: background
Coccidiosis is an economically significant disease of poultry caused by species of Eimeria , a parasitic protozoan.
Output: background
Vitamin D 3 treatment was associated with a significantly lower risk for laboratory confirmed URTI ( RR : 0.54 , CI 95 : 0.34-0.84 , p = 0.007 ) and with a significantly lower mean viral load measured as log 10 viral copies/mL ( mean difference : − 0.89 , CI 95 : -1.7 , − 0.06 , p = 0.04 ).
Output: finding
with high rates of seroprotection ( ≥ 40 HAI titer ) in 82-92 % of all subjects and in 64-85 % of subjects who were seronegative at the time of immunization.
Output: finding
Here we present a metapopulation model of disease spread in Great Britain defined at the level of electoral wards.
Output: purpose
This study aims to systematically review the literature to appraise and synthesise scientific research papers that concern incentives that have been tested to increase data sharing in health and medical research.
Output: purpose
nasopharyngeal aspirates were taken from children with different viral loads and a combined high throughput RNAseq and label free quantitative proteomics approach was used to characterize the nucleic acid and proteins in these samples.
Output: method
High-throughput sequencing ( HTS ) is becoming the state-of-the-art technology for typing of microbial isolates , especially in clinical samples.
Output: background
there are not many methods for prediction of pseudoknotted structures that can incorporate structural information as input.
Output: background
Comparison with control groups suggests that the reduction of NK cells is unique to these severely ill patients.
Output: finding
Lipopolysaccharide-induced pyrexia model was used to evaluate antipyretic activity in Wistar rats.
Output: method
it is necessary to have a deep understanding of mucosal immunology and to test various mucosal vaccination strategies.
Output: purpose
the system classifies alerts by location and disease and then overlays them on an interactive geographic map.
Output: method
Objectives This study was conducted to identify whether these viruses were associated with ARTI among children B5 years of age in rural and peri-urban populations in South India.
Output: purpose
Objectives : The purpose of this study was to investigate factors influencing preventive behavior against MERS-CoV among Korean nursing students.
Output: purpose
Mucosal vaccination offers great advantage for inducing protective immune response to prevent viral transmission and dissemination.
Output: background
tiny , partially doublestranded , reverse-transcribing DNA virus with proteins encoded by multiple overlapping reading frames.
Output: background
BMI , diabetes , and hypercholesterolemia with mild flu in an Iranian population.
Output: purpose
Mafa-B , Mafa-DQB1 , and Mafa-DRB alleles were characterized and their combinations were investigated from 30 macaques of Vietnamese origin by cloning and sequencing.
Output: method
immunocompromised patients experience much higher rates ( 4-10 % ) ( 6 ).
Output: background
In this paper , we show our lab tested solutions in two specific healthcare scenarios.
Output: purpose
for the development of a MS-like disease is explored.
Output: method
formulae derived in order to convert antibody levels as determined by one immunological method to that of another.
Output: finding
We expressed dCAT-1 or mCAT-1 of NIH 3T3 origin in cells that are not normally infectible with ecotropic MLVs and evaluated the transfectants for susceptibility to virus infection and to virus-induced syncytium formation.
Output: method
It begins with an overall introduction of the fabrication followed by an in-depth review on the detection techniques in such devices and various applications with respect to effort and performance to date.
Output: method
to be relentlessly shaped throughout the history of our species.
Output: background
However no such work was conducted in Cambodia or Lao PDR.
Output: background
This research explores perceived importance of safety and security measures from the perspectives of tourists and service providers.
Output: purpose
the largest thoroughbred horse breeding region in Japan , between 2012 and 2014.
Output: method
Conclusion : The median with 95 % CI of R0 of COVID-19 was about 2.28 ( 2.06-2.52 ) during the early stage experienced on the Diamond Princess cruise ship.
Output: finding
Medline , EMBASE , SCOPUS and CINAHL.
Output: method
Untargeted metabolomic analyses based on mass spectrometry were performed on urine samples collected from infants with acute bronchiolitis.
Output: method
there can be severe outcomes , including heart inflammation.
Output: background
blood vessels , and neural regulation of autonomic and cardiovascular modulation.
Output: purpose
exhibits potent antiviral activity against FIV.
Output: background
version 3.69 , was used to estimate immunoglobulin phylogenies from nucleotide sequences that were first aligned using ClustalW2 , as previously described12.
Output: method
Research efforts have focused on innovations that will reduce the morbidity associated with AECB.
Output: background
microglia , astrocytes and neurons in the central nervous system.
Output: background
while the least stable genes failed to do so.
Output: finding
which is to encapsidate the viral genome.
Output: background
Seven residues on the dimer interface were selected for evaluating their contributions to dimer stability and catalytic activity by biophysical and biochemical methods.
Output: method
The genome included at a minimum of 11 predicted open reading frames ( ORFs ) flanked by 5 ′ and 3 ′ untranslated regions ( UTR ) of 211 and 289 nucleotides.
Output: method
Mice ( 20 per group ) were vaccinated i.m. with either PBS + alum or 2-valent ( HRV-16 and HRV-76 ) inactivated HRV + alum in order to establish pre-existing immunity to types 16 and 76 in one group.
Output: method
Using siRNA , we further showed that p300 regulated both constitutive and Tat-mediated GFAP expression.
Output: finding
Neutralization assay results indicated that the infectivity of EV71 and CVA16 strains in RD cells was cross-blocked by IgY in a dose-dependent manner.
Output: finding
In this study , we investigated the stimulatory effect of emodin on BSEP signaling pathway in cholestasis.
Output: purpose
This chapter will summarize the current body of literature related to NMs and viral exposures with a primary focus on immune modulation.
Output: purpose
a disproportionate number of sRNAs ( ,30 % ) were located in genomic region unique to strain 2336 ( ,18 % of the total genome ).
Output: finding
in addition to increased hospitalization costs.
Output: background
lactoferrin as a treatment for calf diarrhea was not beneficial.
Output: finding
A sectorial energy demand analysis and forecasting model was developed to analyze six Chinese provinces with different economic backgrounds.
Output: purpose
The aim of this study was to evaluate the cytotoxicity of Isatis indigotica extracts on human leukemia cell line ( HL-60 ) and the antiviral activity on swine pseudorabies virus ( PrV ) in in vitro assays.
Output: purpose
following vaccination , and as potential immunotherapeutic targets.
Output: purpose
which opens a new horizon in protein science for stability enhancement and function reinforcement via topology engineering.
Output: finding
endocytosis , intracellular trafficking , membrane fusion , and infection.
Output: method
Igs are divided into classes having different physico-chemical structures and biological activities.
Output: background
facilitate attachment and entry into host cells.
Output: finding
All samples were selected and matched for age in these 2 groups.
Output: method
We developed a probabilistic model and used parameters from a published model ( i.e. , InfluSim ) and travel data from Pacific Island Countries and Territories ( PICTs ).
Output: method
Three days later , supernatants were harvested and subjected to virus titration.
Output: method
This type of function can be used 42 to interpret the `` psychological effects '' ( 11 ).
Output: method
exposure to HMPX information and knowledge on HMPX.
Output: method
Therefore , the expressed fusion protein has a good antigenicity.
Output: finding
Additionally , we discuss the question of where Ag presentation is initiated and under what conditions neuroantigens are made available to APCs with special emphasis on which cytokines may be important in this process.
Output: finding
The methods used to study G-quadruplexes have been essential to the rapid progress in our understanding of this exciting nucleic acid secondary structure.
Output: background
In this study , a comparative analysis of the codon usage bias was performed in Aeropyrum pernix K1 and two other phylogenetically related Crenarchaeota microorganisms ( i.e. , Pyrobaculum aerophilum str.
Output: purpose
These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
Output: background
One potential target for SARS-CoV antiviral drug development is the 3C-like protease ( 3CLpro ).
Output: background
Trump pushed an ambitious `` America first '' agenda aimed at transforming the US into a global energy superpower.
Output: background
surgical masks and homemade masks when worn during a variety of activities by healthy volunteers and a simulated patient.
Output: method
To a large extent , the immune correlates of protection against hantavirus are not known.
Output: background
and lactoferrin ( Lf ) in calves with an acute respiratory disease experimentally induced by Chlamydia ( C. ) psittaci.
Output: purpose
The initial interaction between the vesicle and the target membrane has been referred to as tethering.
Output: background
serum , and tissue samples was used to characterize health status.
Output: method
SCUB patterns were also associated with phylogenetic relationship among given species.
Output: background
We interrogate the model using a Latin Hypercube sensitivity analysis to identify which mechanisms are critical to the observed infection of host cells and the release of measured virus particles.
Output: method
with a 50 % inhibition concentration of 3.85 mg/mL.
Output: finding
evaluating the cellular immune response following infection has been hampered by the lack of a number of species-specific immunological reagents.
Output: background
Many viruses cause disease within an infected host after spread from an initial portal of entry to secondary sites of replication.
Output: background
severe acute respiratory syndrome coronavirus ( SARS-CoV ) and transmissible gastroenteritis virus ( TGEV ) in virus-infected and ectopically expressed cells.
Output: purpose
observed unexpected O-glycosylation modifications on the receptor binding domain ( RBD ) of spike protein subunit S1.
Output: finding
By contrast , chemokines such as IP-10 or IL-8 are strongly upregulated.
Output: background
suggesting that larger and more numerous DMVs do not necessarily confer a competitive advantage in primary or continuous cell culture.
Output: finding
and 13 from patient 2 , ranging 1-44 dpd.
Output: method
This distribution and dates of illness onset were used to calculate epidemic trees for each outbreak.
Output: method
are endocytosed at coated pits and subsequently pass into endosomes.
Output: background
The results showed that ID badges and lanyards are not significantly contaminated with common respiratory or gastrointestinal viruses and are unlikely to be a significant vector for nosocomial infection.
Output: finding
this study investigated how two communicative behaviors ( message expression and reception ) in SNSs affected the communicators ' intentions to engage in MERS-preventive behaviors.
Output: purpose
while mitochondria were now found to be closely connected with antiviral immunity.
Output: finding
and its humoral , and cellular immune responses were evaluated in mice.
Output: purpose
the site of a 2014 EBOV outbreak.
Output: background
This study evaluated impact of implementing a previously derived and validated bacteremia prediction rule.
Output: purpose
as well as some of the resources developed for the CC.
Output: purpose
Background : Middle East respiratory syndrome coronavirus ( MERS-CoV ) caused multiple outbreaks.
Output: background
urinary tract , and malarial complications.
Output: finding
The present review will be focused on recent structural and protein-protein interaction information involving two viroporins found in enveloped viruses that target the respiratory tract ; ( i ) the envelope protein in coronaviruses and ( ii ) the small hydrophobic protein in paramyxoviruses.
Output: purpose
Objectives : This work presents a new approach to selecting proper health-based thresholds for a heat warning system which are different from thresholds of heat-health relationship.
Output: purpose
This chapter focuses on specific cell populations and markers involved in cell division and regeneration.
Output: purpose
Mechanical interlocking induces considerable stability enhancement.
Output: finding
and established a virus probe library.
Output: method
Design : Systematic rapid review and meta-analysis.
Output: method
including a pregnant patient who died.
Output: method
and Chlamydophila pneumoniae , and 13 respiratory viruses.
Output: method
Methods : Bacteriophage FX174 was used to trace cross-contamination and evaluate current disinfection practices and a hydrogen peroxide ( H 2 O 2 ) wipe intervention within emergency response vehicles.
Output: method
Molecular dynamics simulations revealed that the L141T mutation disrupts the 3 10 - helix and helps to stabilize the active conformation.
Output: finding
as of Feb 9 , 2020.
Output: method
The article summarizes key aspects of the 3 conditions and provides advice and recommendations for evaluation and treatment based on published reports in the medical literature.
Output: purpose
no comprehensive review articles on the topic of thread-based microfluidics have been published and it is of significance for many scientific communities working on Microfluidics , Biosensors and Lab-on-Chip.
Output: background
Notably , a number of autoantibody responses have been reported in children with KD.
Output: background
All rights reserved.
Output: finding
In this study , we have examined the role of F protein cleavage site sequence in NDV virulence using reverse genetics technology.
Output: purpose
SHAPU patients were at highest risk of harboring anelloviruses in their eyes.
Output: finding
The present study was designed to investigate the antiviral activity of pentoxifylline against JEV in vitro and in vivo.
Output: purpose
we designed and synthesized one-carbon homologated 6 0 - fluorinated-aristeromycin analogues.
Output: method
ESI/MS , and computational calculations.
Output: background
In addition , C58 was used for interspecies hybridisation of murine T cell lines.
Output: method
In contrast , SARS-CoV and TGEV EGFP-nsp15s distributed smoothly in the whole cell and did not form speckles.
Output: finding
Individually housed calves were systematically assigned at birth to 1 of 2 feeding programs : free-access feeding ( ad libitum ) of acidified milk replacer ( ACD , n = 249 ) or traditional restricted feeding ( 3 L fed twice daily ) of milk replacer ( RES , n = 249 ).
Output: method
They were tested for the presence of coronavirus by consensus reverse transcription-PCR assay.
Output: method
We have analysed the role of the milk protein a-casein by inactivating the corresponding gene in mice.
Output: method
In yeast , these complexes function in a number of processes including endoplasmic reticulum-to-Golgi transport ( TRAPP I ) and an ill-defined step at the trans Golgi ( TRAPP II ).
Output: background
Blue diamonds : male ; red squares : female ; green triangles : total population.
Output: finding
Moreover , heparin was shown to bind to ephrin-B3 and to restrain infection of permissive cells in vitro.
Output: finding
The clinical utility of Orthoquin PDI of oral biofilms is an area of active investigation and there is clear potential for wider range of clinical applications.
Output: background
We report recent extensions to this approach.
Output: purpose
Bovine colostral Igs provide the newborn calf with passive immune protection against microbial infections until the calf 's own immune system matures.
Output: background
14 and 36 for hemagglutination inhibition ( HAI ) testing.
Output: method
Nasal lavage fluids and turbinate epithelial cells were collected prospectively from 111 CRS patients and 50 controls.
Output: method
We also discuss the strengths and limitations of various assay platforms and describe a staged strategy for viral diagnostics.
Output: purpose
were immediately performed and were continued for 1 h , without success.
Output: finding
EV-D68 was identified in 153/907 ( 16.8 % ) of patients tested.
Output: finding
The combination of microarray technology and sensitive isothermal nucleic acid amplification at 38 °C allows for a multiparameter analysis on a rather small area.
Output: method
Expression of a small ( 35aa ) sequence in Domain III alone was sufficient to form speckles for all 3 viral nsp15s.
Output: finding
Coronaviridae is classified under the Nidovirale order ( 20 ).
Output: background
quantifying the interplay between the HCoV-host interactome and drug targets in the human protein-protein interaction network.
Output: purpose
We found that mice shed viruses distinct from input viruses because they formed extremely large plaques in cell culture.
Output: finding
acceptability , flexibility , stability and utility.
Output: method
A variant was previously identified and showed a distinct S1 gene homology with other local strains.
Output: background
Abreva is incorporated into the cellular plasma membrane and prevents fusion steps essential for HSV-1 entry into epithelial cells ( 8 ).
Output: background
the most efficacious 1,7-DAAC-based antimalarials employ a mechanism of action analogous to that of 4,7-ACQ-based antimalarials and are well tolerated by normal cells.
Output: finding
By studying phylogenetic trees , scientists gain a better understanding of how species have evolved while explaining the similarities and differences among species.
Output: background
In Section 3 , preliminary mathematical analysis of the proposed model is carried out.
Output: method
We hypothesized that EMR-based surveillance systems that incorporate seasonality and other long-term trends would discover outbreaks of acute respiratory infections ( ARI ) sooner than systems that only consider the recent past.
Output: method
cDNA was synthesized by using the Improm-II Reverse Transcription System and random primer ( Promega , Madison , WI , USA ).
Output: method
We found that PI3K-Akt-mTOR signaling is essential in sustaining rotavirus infection.
Output: finding
The phylogenetic analyses based on avian and mammalian coronaviruses showed the analysed IBV as closely related to turkey coronaviruses and distantly related to thrush and munia coronaviruses.
Output: finding
and brain sections stained for pathological markers or analyzed for proinflammatory marker expression.
Output: method
The median incubation period was 3.0 days and from illness onset to hospital admission was 2 days.
Output: finding
Furthermore , the oxygenation index in the survival group was significantly higher when compared with that in the fatality group.
Output: finding
Further , our results indicate that age factors should be considered when investigating the vaccination and therapeutic strategies for severe IAV infection.
Output: finding
Double-stranded RNA-dependent protein kinase ( PKR ) is regulated by reovirus structural proteins.
Output: finding
The APMVs produced mild or inapparent clinical signs in hamsters except for APMV-9 , which produced moderate disease.
Output: finding
and a less viscous gel diluent was compared.
Output: method
Here , we report our findings of a head-to-head comparison of two viral vectors modified vaccinia Ankara ( MVA ) and a novel replication-competent modified vaccinia Tian Tan ( MVTT ) for inducing neutralizing antibodies ( Nabs ) via intramuscular and mucosal vaccinations in mice.
Output: purpose
which could be attributed to that fact that several essential immediate early viral proteins for virus replication were impacted by resveratrol.
Output: finding
Applicable models to improve adaptation in individuals include Folkman and Greer 's framework for stress appraisal and coping along with psychological first aid.
Output: background
Material and methods : This diagnostic study was conducted from January 2014 until June 2015 in three major educational medical centers , Tehran , Iran.
Output: method
This review aims to provide an updated close-up of the literature on G4s in viruses.
Output: purpose
fecal samples ( n = 59 ) were collected from dogs with or without diarrhea ( n = 21 and 38 , respectively ) in the Republic of Korea ( ROK ) in 2012.
Output: method
In this review , we will discuss the relationship between viruses and autophagy and summarize the current knowledge on the functions of viral proteins contributing to affect autophagy process.
Output: purpose
and parvovirus B19 in patients with HIV disease.
Output: purpose
We assumed that all of the individuals in a population group have the same location visiting schedule on weekdays.
Output: method
and self-efficacy related to SARS and eight other diseases.
Output: method
Irrespective of previous diagnosis , nasopharyngeal or nasal swab specimens were randomly selected and tested using real-time PCR from three sites during 2007 from patients younger than 6 years old.
Output: method
before the ophthalmological check , it is mandatory to know if the patient has COVID-19 symptoms and if the patient has recently been in contact with a confirmed COVID-19 case.
Output: background
is involved in targeting of stable RNA for degradation.
Output: finding
in the month of the epidemic growth.
Output: method
and incubated with 5 µg/ml of FY1 or MEDI8852 on ice for 1 hour.
Output: method
In this study , we explored the potential of the plant-derived photosensitizing agent Orthoquin TM to mediate photodynamic inactivation ( PDI ) ( 10 ) of virions.
Output: purpose
and at identifying a possible correlation between viral loads and disease severities.
Output: purpose
In this chapter , we describe several databases ( such as GENEDB , BRENDA , KEGG , METACYC , the THEM-PEUTIC TARGET DATABASE , and CHEMBaNK ) and algorithms ( including PATHOLOGIC , PATHWAY HUNTER TOOL , AND AUTODOCI0 which have been developed to facilitate the bioinformatic analyses underlying these approaches.
Output: purpose
Results.
Output: finding
This review highlights the key role that autophagy plays in the innate immune system and the acquired immune system.
Output: purpose
and the energy parameters of HotKnots V2 .0.
Output: method
the ability to cause systemic infection was the strongest predictor of severe disease.
Output: finding
the use of personal protective equipment during MERS-CoV compared with the period before MERS-CoV increased dramatically from 2,947.4 to 10,283.9 per 1,000 patient-days ( P < .0000001 ) for surgical masks and from 22 to 232 per 1,000 patient-days ( P < .0000001 ) for N95 masks.
Output: finding
Induced sputum and serum were collected.
Output: method
Objectives : To evaluate registered nurse compliance with standard precautions and to analyze the factors that affect compliance.
Output: purpose
it is difficult to synthesize stable prodrugs of this compound.
Output: background
in-depth interviews , and direct field observation.
Output: method
Atmospheric aerosol particles are presumably one of the media.
Output: background
In total , 485 calves ( ≤ 21 d of age ) were enrolled at first diarrhea diagnosis ( fecal score ≥ 2 defined as loose to watery ) and randomly assigned to receive an oral dose of lactoferrin ( 3 g of lactoferrin powder dissolved in 30 mL of water ) or 30 mL of water ( control ) once daily for 3 consecutive days.
Output: method
some underlying design principles and the prospects for future developments.
Output: purpose
men and those with lower education levels.
Output: finding
Epigenetic research occupies a prominent role in tumor biology.
Output: background
but few studies considered an evolving system with competing strategies.
Output: background
It is suggested that the alteration in the nerve cell bodies in the hypothalamic nuclei is caused by retrograde axonal signals from these target areas.
Output: finding
G. hirsutum ( AD 1 ) and G. barbadense ( AD 2 ) were analyzed in the present study.
Output: method
specific antibodies , and a potential role for humoral immunity in KD pathogenesis or diagnosis.
Output: purpose
Rotavirus were detected in 22,7 % of the specimens and various particles ( Adenovirus , Astrovirus , Coronavirus ) in 9,1 % of the specimens.
Output: finding
The present report constitutes an attempt to improve and modify the existing clinical evaluation method for new antimicrobial agents to treat respiratory infections.
Output: purpose
can be clearly displayed through their cellular automata images.
Output: purpose
Defining the key components of effective implementation strategies and the ideal method ( s ) of assessing hand hygiene compliance are dependent on a range of factors associated with the healthcare system.
Output: method
A step-by-step evaluation of dual-labeled FRET substrates for the protease calpain is reported.
Output: purpose
Paromomycin ( 100 mg/kg ) was used as a positive control.
Output: method
Virulent BCV was actively introduced in one of the groups by means of a transmitter calf.
Output: method
and 72 C for 15 min.
Output: method
1.8 mM dNTPs and at an incubation temperature of 67.1 °C.
Output: background
tethering is critical to ensuring that specificity is achieved.
Output: background
pCAGGS-NP , and they were stimulated using the synthesized peptides.
Output: method
This study aimed to examine the relationship between macroeconomic and nonmacroeconomic variables and hotel stock returns using hotel companies listed on the Taiwan Stock Exchange.
Output: purpose
This study aimed to investigate transitional changes in the incidence of OFNH among renal transplant recipients by MRI.
Output: purpose
and no patients succumbed through 28 th February.
Output: finding
regulation of transcription and processing of the pre-messenger or telomeric RNA.
Output: background
Healthcare workers accounted for a large proportion of persons with severe acute respiratory syndrome ( SARS ) during the worldwide epidemic of early 2003.
Output: background
Purpose To generate and characterize a specific monoclonal antibody ( mAb ) against recombinant human RANK receptor and to develop an antiresorptive strategy using this mAb as an osteoclast-targeting platform that selectively targets osteoclast cells whilst delivering an attached ( i.e. chemically conjugated ) active drug cargo.
Output: purpose
consecutive adult patients suspected to be septic ( n = 432 ) were analyzed with cultures from blood and nasopharynx plus multiplex PCR for respiratory viruses on the nasopharyngeal specimen.
Output: method
Experiments to study the mechanism of antiviral action of pentoxifylline using in vitro translation of viral mRNA suggested that the drug did not interfere either with early or late protein synthesis but most likely exerted its action on virus assembly and/or release.
Output: finding
and to compare anaesthetic regimen and clinical outcomes in parturients with or without COVID-19 undergoing cesarean delivery.
Output: purpose
Third , rotavirus may sequester NF-κB in viroplasms.
Output: background
resulting in a detection limit of 5 ng/mL ( or 1 ng in terms of amount ) and enhanced compatibility with practical applications such as clinical biopsy.
Output: finding
Therefore they need data to assess the possible impact of interventions.
Output: background
This study was undertaken to design a reliable multi-epitope peptide vaccine against highly conserved immunodominant heat shock 70KDa protein of Cryptococcus neoformans var.
Output: purpose
two group sizes , and their interaction on nursery pig performance to serve as a model for future AGP alternative studies.
Output: purpose
Enzymatically inactive cysteine mutants were retained in the endoplasmic reticulum as shown by high-resolution imaging and Endoglycosidase H digestion.
Output: finding
Here , we demonstrate a viral detection strategy based on synthetic biology principles to detect a specific viral function rather than a particular viral protein.
Output: purpose
We postulated that a quantitative analysis of beat pattern would improve PCD diagnosis.
Output: purpose
These interactions can also indirectly affect the host response to viral infection.
Output: background
The botanical plant extract Orthoquin TM is a powerful photosensitizer with antimicrobial properties.
Output: background
which was historically used as a smallpox vaccine for millions of Chinese people.
Output: background
Fortunately , the biomedical community has been able to rapidly generate sequence data so these pathogens can be readily identified.
Output: background
In the 1990s , the popularity of this herbal medicine began to attract the attention of scientists worldwide.
Output: background
and a Bacillus-based direct-fed-microbial ( DFM ) plus resistant potato starch ( RS ) ( DR ; NC + DFM + RS ).
Output: method
Therefore , the FFD-Markov-chain model is able to greatly reduce the computing cost for predicting transient particle transport in indoor environments.
Output: finding
which in turn exerts anti-rotavirus effects.
Output: finding
or are under development in India.
Output: purpose
GLTSCR2 should be seriously considered as a therapeutic target for developing broad spectrum antiviral agents to effectively control viral infection.
Output: finding
Autophagy was also reported to suppress the magnitude of host innate antiviral immunity in certain cases.
Output: background
purification , and characterization of vaccine protective antigens in veterinary vaccines was also identified as a priority.
Output: finding
a cell culture system used for manufacturing of MVA vaccines.
Output: method
and it does not require a multiple sequence alignment.
Output: background
Nonetheless , it is clear that the changes that have increased asthma have acted on allergic children.
Output: finding
The ocular anellovirus load in SHAPU and non-SHAPU patients did not differ and no SHAPU-specific anellovirus variant was detected.
Output: finding
NS7b and NS8 have previously been shown to affect immune response signaling in the SARS-CoV experimental model.
Output: finding
The consequence of systemic vasoconstriction is volume and pressure loading in the pulmonary circulation.
Output: finding
to facilitate management of severe sepsis and septic shock in emergency department.
Output: purpose
The most cited article was referenced 4909 times.
Output: finding
and several modes of viral evolution that can affect viral pathogenesis.
Output: purpose
and to enhance the abovementioned model with a tourism database.
Output: purpose
In this paper we present a tool to address these issues : a cellular automata model describing critical aspects of in vitro viral infections taking into account spatial characteristics of virus spreading within a culture well.
Output: purpose
Quantitative analysis and chromatographic fingerprinting for the quality evaluation of a Chinese herb Scutellaria baicalensis Georgi using capillary electrophoresis ( CE ) technique was developed.
Output: purpose
and any changes to the antibiotics regimen as results of the blood cultures.
Output: method
We hypothesize that M. haemolytica colonization of cattle during its commensal state may include biofilm formation.
Output: purpose
vaccine-induced immunity and self-reported symptoms.
Output: purpose
which consisted of 145 serum specimens from patients confirmed by RT-PCR to be positive for human respiratory infections.
Output: method
We collected serum samples from 50 healthy blood donors ( Cohort A ) as negative controls Sanquin Blood Bank ( Rotterdam , the Netherlands ) obtained written informed consent for research use.
Output: method
designated BALB/cV , exhibits an intermediate mammary tumor incidence ( 47 % ) and harbors a distinct milk-transmitted mouse mammary tumor virus ( MMTV ).
Output: background
Our data have implications for people who maintain low levels of anti-VTT Nabs after historical smallpox vaccination.
Output: finding
but highly infectious organisms is important as well.
Output: background
Chronic obstructive pulmonary disease ( COPD ) is a disease with high prevalence and substantial associated economical burden.
Output: background
Here , we dissect the contributions of the individual complement activation pathways to the protection from WNV disease.
Output: purpose
The highest mean titre obtained by ELISA was approximately 1.5-3.5 times greater than those obtained by the other techniques whilst CFT gave the lowest values.
Output: finding
Introduction : This study compares the detection of 14 common respiratory viruses by two different real-time reverse transcription polymerase chain reaction ( rRT-PCR ) methods : in house singleplex tests developed by the Centers for Disease Control and Prevention and the commercially available Fast Track Diagnostic ( FTD ® ) Respiratory Pathogens 33 multiplex test.
Output: purpose
In this study , we propose a more flexible geometric structure to be used as a spatial or spatio-temporal scanning window.
Output: purpose
Methodology/Principal Findings : We report results of virological analyses performed in the Public Hospitals of Marseille during the first months of the outbreak.
Output: method
is essential to the virus life cycle.
Output: background
and their relationships in this treatise based on a multi-subnet composited complex network model ( MCCN ).
Output: purpose
In the present study , we characterized the previously unidentified CPV-2c variant and investigated the distribution of CPV-2 variants in Taiwan.
Output: purpose
while means and standard deviations were calculated for continuous variables.
Output: method
it outlines the key pillars of the emerging global energy order.
Output: purpose
We reviewed the data and metadata availability and quality of these studies.
Output: finding
as these are most interesting from an immunological point of view.
Output: purpose
Seven days after treatment , many immature Schwann cells but no oligodendrocytes were found between the denuded axons.
Output: finding
suggesting that PAP observed in this family could be inherited as an autosomal-dominant trait from the mother.
Output: finding
and ultrastructural analysis was performed using electron microscopy.
Output: method
Evidence supports the goal of developing and maintaining an organizational culture of resilience in order to reduce the expected stress of an influenza pandemic on healthcare workers.
Output: finding
and efficiencies of 53 % to 79 % for surface samples in localized systems.
Output: method
as well as cell viability.
Output: method
Seventy-one patients completed the 15-year follow-up.
Output: method
Students completed weekly electronic surveys and submitted self-collected mid-turbinate nasal flocked swabs during September and October in 2010 or 2011.
Output: method
We assessed the impact of social distancing caused by this extreme weather event on the transmission of respiratory viruses.
Output: purpose
A decision tree algorithm describing our institutional guidelines for precautions for operating room team members was created.
Output: method
β , and γ alone and in combination with ribavirin drugs and inoculated with SFTS virus.
Output: method
clinical , and laboratory profiles of acute febrile illness patients to diagnose dengue.
Output: purpose
This study seeks to characterize the views of individuals on the nature and limits of this duty.
Output: purpose
This article reviews the recent progress for immune biology of Vγ2 Vδ2 T cells in infections.
Output: purpose
In this review , the characteristics of the feline APR are described.
Output: purpose
oropharyngeal mucosal sites , and lymph nodes draining the pharynx.
Output: finding
and was propagated 8 times in HRT-18 cells.
Output: purpose
This makes amyloid fibrils a challenging focus for inhibition studies because the peptides and proteins that form amyloid fibrils can not be targeted based on a sequence motif.
Output: background
Immune responses are a double-edged sword.
Output: background
but also their common orientation on one side of the peptide that is engendered by the WX 2 WX 2 W motif.
Output: finding
and the β3-β4 turn failed to contact pAPN.
Output: finding
international health agencies have set the goal of eliminating HBV infection by 2030.
Output: background
The findings provide a scientific basis for the use of K-601 as anti-inflammatory and antipyretic agent in traditional Chinese medicinal practice.
Output: finding
Broncho-alveolar lavage ( BAL ) cells were counted and differentiated.
Output: method
in data compression and oligonucleotide microarray production.
Output: background
The PostPFree from the final three months in 2015 was compared to BTM test results from March 2016 using a Wilcoxon Rank Sum Test.
Output: method
We investigated the prevalence and the clinical impact of respiratory virus infection in adult patients with HCAP.
Output: purpose
attitudes , infection control practices and educational needs of HCWs in the Kingdom of Saudi Arabia to MERS coronavirus and other emerging infectious diseases.
Output: purpose
In brief , peripheral blood mononuclear cell ( PBMC ) samples were obtained from a single healthy donor after vaccination following written consent.
Output: method
We also propose and illustrate methods for aggregating specific `` bug-drug '' data.
Output: method
DMVs is why they exist in the first place.
Output: finding
and discuss the past and future drivers in view of future challenges in an evolving scenario.
Output: purpose
Coronavirus envelope ( E ) protein is a small integral membrane protein with multi-functions in virion assembly , morphogenesis and virus-host interaction.
Output: background
Section 4 is devoted to the global stability of the endemic equilibrium using geometric approach while 52 in Section 5 backward bifurcation and forward bifurcation with hysteresis effect is presented.
Output: method
The PFGE banding patterns were compared visually.
Output: finding
their epidemiology , pathogenesis , clinical features , and management and control.
Output: purpose
In this review , we discuss some of the recent findings of host cell factors that might be exploited by HCoVs to facilitate their own replication cycle.
Output: purpose
Thailand , were used for model construction and validation.
Output: method
Several proteins known to be cleaved by other viruses were submitted to prediction as well as proteins suspected relevant in coronavirus pathology.
Output: method
Mature virions then exit through the cellular secretory system.
Output: background
was detected in 2 Myotis bats.
Output: finding
Treated and nontreated cells were infected with CyHV-3 and virus binding and infection parameters were assessed using RT-qPCR , immunocytochemistry and virus titration.
Output: method
Empirical Mode Decomposition ( EMD ) was applied to properly describe the trends of HIV and AIDS incidence.
Output: method
IRF5 , and IRF7 to prevent their induction of IFN.
Output: background
This pandemic probably originated in central Asia and began spreading westward along major trade routes.
Output: background
It appears that more efforts should be made and preventive measures should be implemented for children and adolescents in Hong Kong.
Output: finding
as enrichment devices would have an impact on endpoints commonly measured during the conduct of the National Toxicology Program ( NTP ) 13-week studies.
Output: purpose
that contemporaneousand cross-strain nAb responses against SARS-CoV spike protein exist during natural infection.
Output: purpose
and how specific oligosaccharide structures facilitate these functions during viral pathogenesis.
Output: purpose
We will also discuss emerging applications and future directions of protein microarray technology in the global frontier.
Output: purpose
It briefly reviews the history of chiropteran viruses and discusses their emergence in the context of geography , phylogeny , and ecology.
Output: purpose
It also inhibited NF-jB activation and reduced the upregulation of proinflammatory cytokines induced by the infection.
Output: finding
Data were compared between survivors and non-survivors.
Output: method
Materials and Methods : This retrospective study enrolled all patients admitted to a 12-bed SARS intensive care unit ( ICU ) in a tertiary care medical center in Taipei between May 15 and July 17 , 2003.
Output: method
whereas RIG-I and SG markers did not.
Output: finding
Here , we discuss issues related to the establishment of this technology and areas that are highly promising for its application.
Output: purpose
Today , it estimated that about one-third of the world population is infected with the TB bacillus.
Output: background
untreated subjects , indicating that this antibody may be a suitable MERS-CoV treatment.
Output: finding
Gammaand Deltacoronaviruses based on sequence comparisons of entire viral genomes ( 21 , 22 ).
Output: background
As a consequence of infection there are alterations in the permeab ~ dity of the plasma membrane which may contribute to cellular damage.
Output: background
Currently , it is unclear if flexibility in this region is an inherent property of prefusion RSV F or if it is related to inadequate stabilization of site Ø in the engineered variants.
Output: background
In this work we undertook a mutational analysis to attempt to identify specific amino acid sequences within the spike glycoprotein crucial for molecular mimicry of Fc ␥ RII.
Output: purpose
Purpose : COVID-19 ( coronavirus disease 2019 ) is a public health emergency of international concern.
Output: background
In this paper , we present an algorithmic solution to produce coding sequences that follow exactly a primary amino acid sequence and a desired GC-content.
Output: purpose
translation , replication , and genomic stability.
Output: background
The frequency of disease ( diarrhea , dehydration , depression , signs of respiratory disease ) through 35 d following diarrhea diagnosis was not significantly different for calves in the lactoferrin and control groups.
Output: finding
Here we report a novel method for identification and typing of HEVs based on information derived from their whole genomes.
Output: purpose
it should be noted that the analytical method can influence the composition of the library ( e.g. , trace of acid in liquid chromatography ( LC ) ).
Output: background
there remains a lack of available reagents for studying hamster immune responses.
Output: background
Objectives : Severe influenza can lead to Intensive Care Unit ( ICU ) admission.
Output: purpose