niryuu/sni-each-converted huggingface dataset:
we added new factors to test whether causal mechanisms and pathogenic landscapes could be more specifically identified.
Output: purpose
In addition , we demonstrate that a predicted 3 = RNA stem-loop structure at a noncanonical spacing downstream of the shift site is required for efficient frameshifting in TMEV and that frameshifting also requires virus infection.
Output: finding
what vaccines are available , and how PEDV can be treated.
Output: purpose
viral RNAs and serum IgM-IgG antibodies to SARS-CoV-2 were measured respectively.
Output: method
However , its ability to inhibit Japanese encephalitis virus ( JEV ) replication has not yet been studied.
Output: background
per-capita contact rates in schools were assumed to be double that in workplaces 6.
Output: method
we studied the SARS-associated virus by electron microscopy and molecular biological technique.
Output: purpose
which facilitate multiplexing , and ( ii ) artificially expanded genetic information systems ( AEGISs ) , which enable low-noise PCR.
Output: method
employed an elegant modeling approach to capture the distributions of the number of secondary cases that arise in the community and health care settings in the context of changing population behaviors and increasing hospital capacity.
Output: background
The possibility of enhancing the chemical bond between Gln and Ser based on the `` distorted key '' theory ( Anal.
Output: background
Taken together , these results demonstrate that all nine known APMV serotypes are capable of replicating in hamsters with minimal disease and pathology.
Output: finding
this article attempts to provide a timely and comprehensive review of the swiftly developing research subject.
Output: purpose
and inferred the probability and characteristics of large outbreaks.
Output: method
from its ` discovery ' in the late 1920s to the management regime of the early twenty-first century.
Output: purpose
are used as receptors for adhesins expressed by the pathogenic Neisseriae.
Output: background
mRNA and cytokine/chemokine secretion profiling were investigated for human monocyte-derived macrophages infected in-vitro with Influenza virus A/H1N1 and/or Streptococcus pneumoniae.
Output: purpose
and we highlight its relationship with the effort required to control an epidemic when interventions are targeted at randomly selected households.
Output: finding
Simulations are helpful for examining the potential consequences of control options under different scenarios.
Output: method
Fifteen cytokines and chemokines were detected in the blood of the patient with SARS by means of a bead-based multiassay system.
Output: method
and peak neutrophil response at 24 h post-injection.
Output: finding
remnant DNA and environment should be considered in data analysis and results interpretation.
Output: finding
Unexpectedly , the morphology and proliferation rate of iPSC were changed after nCoVN expressing for two weeks.
Output: background
Scheme 1 Reversible reactions used in protein-templated DCC to identify bioactive compounds.
Output: finding
and to examine associations between PWD and other dam-related characteristics ( age , litter size , body mass index , and weight and number of active mammary glands of the dam ).
Output: purpose
columnar , ciliated , and hyperplastic.
Output: finding
Isolation and functional studies on feline bone marrow derived macrophages.
Output: background
including in China , were infected and approximately 770 people died.
Output: background
Study design : Whole-genome and S gene sequences were obtained from nasal swabs using next-generation sequencing and phylogenetic trees were constructed.
Output: method
but also cause severe lung injury and higher mortality rate.
Output: finding
All discussions were conducted in the local dialect of respondents.
Output: method
Primary outcome measures : Fall-related injury number and rates were calculated and reported.
Output: method
and its catalytic center was shown to consist of H 2820 and C 2922 residues.
Output: background
as measured by qPCR for the HSV-1 genome.
Output: finding
Naturally emerging and deliberately released pathogens demand new detection strategies to allow early recognition and containment.
Output: background
and myasthenia gravis , as well as the advantages and disadvantages of each model and how they correlate or differ from their human counterpart.
Output: purpose
but the variable factors within these two routes are not well described.
Output: background
i.e. , airports , in the returning travelers in most of the countries with limited resources.
Output: background
A good agreement between PanCoV-RT-PCR and BCoV-RT-PCR to detect BCoV was identified ( j = 0.68 , 95 % CI : 0.392 to 0.967 ; P < 0.001 ).
Output: finding
The results of western blotting and bidirectional immune agar diffusion testing revealed that the IgY had cross-binding properties in EV71 and CVA16 strains through targeting the envelope proteins ( VP0 , VP1 and VP3 ) of EV71 and CVA16.
Output: finding
We modified and optimized a method for generating tracheal epithelial cultures from Syrian golden hamsters and characterized the cultures for cell composition and function.
Output: method
that mice fail to mount protective MyD88-independent IFN-I responses.
Output: background
( 2 ) whether concentrations of oxygen sufficient to potentially cause oxidant injury result in morphologic epithelial alterations similar to those that occur in ozone toxicity : and ( 3 ) if the combined oxidant insult of oxygen and ozone results in more severe damage to the tracheal epithelium than occurs with ozone in air.
Output: method
Together , these findings suggest that the broad antiviral effects of Orthoquin-mediated PDI may stem from damage to viral attachment proteins.
Output: finding
biological , and physical therapies.
Output: method
We have been using the human Ad12 Syrian hamster cell system for the analysis of epigenetic alterations in Ad12infected cells and in Ad12-induced hamster tumors.
Output: background
N3 , by computer-aided drug design and subsequently determined the crystal 39 structure of COVID-19 virus M pro in complex with this compound.
Output: method
A 1520 bp region of Cochlosoma anatis mtDNA 16S gene was subjected to DNA sequencing and a 466 bp portion was compared with other protozoan 16S sequences to develop PCR primers specific for C. anatis.
Output: background
Here , we report a 67-year-old woman with rapidly progressive pulmonary M. abscessus infection who developed OP and acute respiratory failure ( ARF ).
Output: purpose
We conducted a retrospective study of children with histologically confirmed ELP at Red Cross Children 's Hospital , South Africa.
Output: purpose
type I interferon ( IFN ) and the ubiquitin proteasome pathway.
Output: method
CoVs are a group of large enveloped RNA viruses under the Coronaviridae family.
Output: background
We outline what methods are currently available for use in hamsters and what is readily used as well as what limitations still exist and future perspectives of reagent and assay development for hamsters.
Output: method
2.9 ( 1.0-5.0 ) , and 11.9 ( 8.3-15.7 ) per 100,000 person-years , respectively.
Output: finding
Background : Governments are preparing for a potential influenza pandemic.
Output: background
with consistently significant and robust effect on mortality rates.
Output: background
it is important to recognize such findings in order to include infection with the H1N1 virus in the differential diagnosis of respiratory symptoms.
Output: finding
Ischemia , infection , and enteral feedings are suspected to be involved in the pathophysiology.
Output: background
ACD calves had access to milk replacer for 12 h/d and RES calves were offered only one feeding of milk replacer ( 3 L ) daily.
Output: method
The intermediate hosts of most of the human coronaviruses are known , but not for HCoV-NL63.
Output: background
with a G + C content of 37.27 %.
Output: method
transcriptional coactivators that facilitate this process are incompletely understood.
Output: background
partial thromboplastin time and factors V and VIII.
Output: method
the FDOD method previously developed by us was applied to comparing complete genomes from 12 SARS-CoV isolates to those from 12 previously identified coronaviruses and an unrooted phylogenetic tree was constructed.
Output: method
Methods : We conducted a cross-sectional study of pediatric patients with respiratory symptoms in a Singaporean pediatrics hospital.
Output: method
and is rapidly evoked when the pathogen-associated molecular patterns ( PAMPs ) of viruses are sensed.
Output: background
Emerging evidence indicates that pro-inflammatory cytokines modulate brain excitability.
Output: background
epidemiological and outbreak investigations , and in complementing preventive approaches for the control and management of foodborne pathogens.
Output: background
up to March 8 , 2018.
Output: method
Individual cysteine clusters were altered via cysteine-to-alanine amino acid replacement and the modified S glycoproteins were tested for their transport to cell-surfaces and ability to cause cell fusion in transient transfection assays.
Output: method
Cases were not more likely to be hospitalized than controls.
Output: finding
Trial registration : Clinical Trials Registration : NCT01158560.
Output: finding
Mycobacterium bovis , which lost its virulence in humans by being specially subcultured in an artifi cial medium.
Output: finding
we here present a Y2H protocol that is well suited for high-throughput screening.
Output: method
This study aimed to assess the uptake of recommended vaccines and to identify the factors associated with the vaccines ' uptake among Malaysian Hajj and Umrah pilgrims.
Output: purpose
Attention is given to human behavior regarding the family dog and responsible dog ownership.
Output: background
and observational study included 55 patients with COVID-19 who were transferred to Shenyang Sixth People 's Hospital between January 20 and March 15 , 2020.
Output: method
we adopt a few simplifications.
Output: method
Results : Twelve non-cases drank unpasteurized camel milk and had contact with camels.
Output: finding
computational , and combinatorial strategies and assess the potential of these approaches for the development of new vaccines and immunotherapeutics.
Output: purpose
affecting over 100 countries in a matter of weeks.
Output: background
The present study was undertaken to determine immune response and protection efficacy of a spike ( S ) protein fragment containing neutralizing epitopes ( 4F/4R ) of turkey coronavirus ( TCoV ) by priming with DNA vaccine and boosting with the recombinant protein from the corresponding DNA vaccine gene segment.
Output: purpose
The underlying mechanisms and potential protective role of exogenous PTX3 as a therapy should be further explored.
Output: finding
Interstitial inflammation , parenchymal fibrosis and bronchiolitis obliterans scores were significantly higher in KO mice.
Output: finding
Purpose : This study was designed to identify factors associated with death by 6 months post-intensive care unit ( ICU ) discharge and to develop a practical mortality risk score for extracorporeal membrane oxygenation ( ECMO ) treated acute respiratory distress syndrome ( ARDS ) patients.
Output: purpose
Arabian strains of the virus should be tested for changes in virulence and transmissibility.
Output: finding
which we have validated in functional studies.
Output: finding
and use of blood culture in CAP is still increasing.
Output: purpose
In this research article , an attempt has been made to understand the qualitative behavior of a virus infection model with Lytic and Non-Lytic Immune Responses by perturbing with randomness ( white noise ) via Lyapunov technique.
Output: purpose
This document discusses routes of transmission of infection and the principles of current infection control measures.
Output: purpose
to name only a few examples.
Output: background
Now is the time for us to reframe our role in the health system that is evolving to a process of care focused on population health and patient safety that pays providers for value they bring to achieve those goals.
Output: purpose
Objectives : We set out to assess the quality of MERS-CoV molecular diagnostics worldwide.
Output: purpose
as well as existing , vaccines , making them more effective.
Output: finding
including a summary of basic knowledge of their biology.
Output: purpose
In addition , a brief review of two pathways intimately associated with cell division is provided because of their potential for pharmacologic manipulation.
Output: purpose
and ( 3 ) builds data-based simulation models to identify factors that most strongly affect patterns of prevalence.
Output: purpose
with distinct `` club-like '' projections formed by the spike ( S ) protein ( 23 , 24 ).
Output: background
Methods : Patients admitted to two sentinel hospitals between 2010 and 2014 who met the SARI case definition were enrolled.
Output: method
as were the WBC count and the C-reactive protein and procalcitonin levels.
Output: finding
G6PD genotyping for Mahidol , Kaiping and Mediterranean mutations was performed for 128 out of 196 samples by real-time multiplex PCR.
Output: method
the benefits of vaccination and antiviral use might be significantly compromised if these control programs are not designed appropriately.
Output: finding
and until death 44 was 15.93 ( 95 % CI : 13.07 , 18.79 ).
Output: finding
Recipient PTX3 deficiency enhanced chronic rejection-like lesions by promoting a fibrotic process in the airways and lung parenchyma.
Output: finding
This paper presents an empirical spatio-temporal analysis of epidemiological data concerning 2321 SARS-infected patients in Beijing in 2003.
Output: purpose
Abstract Bovine viral diarrhea virus ( BVDV ) is an important pathogen of cattle that plays a complex role in disease.
Output: background
indicating that the membrane is essential in stabilizing the peptide conformation that will be able to inhibit viral infection.
Output: finding
nurses , pharmacist and technicians individually.
Output: purpose
suggesting that they were stably expressed in the shell gland tissue.
Output: finding
a kinase required in interferon signaling.
Output: background
inhibit growth of vaccinia virus ( VACV ) in vitro.
Output: purpose
covered in a separate article.
Output: purpose
but also suggest novel strategies that target protein-protein interactions as much needed antivirals.
Output: purpose
including outbreaks of highly transmissible diseases through high quality care within the context of universal health coverage.
Output: background
• We investigate the similarity among US and Chinese stock indices for the Asian currency crisis and the global financial crisis.
Output: purpose
Herein , we report a facile approach to increase antigen size to achieve not only fast but also effective responses against the recombinant HA/H7N9 protein via a simple conjugation of the protein onto the surface of nanodiamond particles.
Output: purpose
The majority of APMV-infected hamsters exhibited transient histological lesions that self resolved by 14 days post infection ( dpi ).
Output: finding
Regarding viral circulation , BCoV was detected in 10 % ( 3/30 ) of all calves and BCoV IgG1 Ab seroconversion was detected in 42 % of the total animals showing that almost half of the calves were infected with BCoV.
Output: finding
in the entry of HAdV-D37 into primary human corneal fibroblasts.
Output: purpose
Synthesis of nitrogen and sulfur heterocyclic mimics of furanoflavonoids have been achieved for the first time.
Output: background
their various modes of action and gives an update on the applications of intrabodies in human diseases.
Output: purpose
Survival of SARS-CoV strain GVU6109 was studied in stool and respiratory specimens.
Output: method
Therefore , vaccination targeting older children might protect infants from RSV infection.
Output: finding
in this study we demonstrate that direct delivery in mice of an infectious ZiKV cDnA clone allows the rescue of recombinant ( r ) ZiKV in vivo.
Output: purpose
Additionally , some pigs were euthanatized after a second LPS administration for bronchoalveolar cell analysis and virological examinations of the lungs.
Output: method
Time of emergence of clinical signs and survival rate were not significantly different between the two groups.
Output: finding
there are several other recognizable uses and potential impact of these systems on the public and global public health.
Output: background
The purpose of this case study was to determine how the program affected the shelter cat intakes over time.
Output: purpose
The double proline mutant V55P / S71P displayed no fusion activity despite being well expressed at the cell surface as a proteolytically cleaved trimer that could bind red blood cells and change conformation at low pH. The impairment in fusion for both V55P and V55P/S71P was at the level of outer leaflet lipid mixing.
Output: finding
Gross pathology and histopathological findings were background changes and were not considered enrichment-related.
Output: finding
Intriguingly , a minor proportion of the SARS-CoV E protein was found to be modified by N-linked glycosylation on Asn 66 and inserted into the membranes once with the C-terminus exposed to the luminal side.
Output: finding
In addition , we provide an up-to-date list of bat species in China.
Output: purpose
A value of p < 0.05 was considered statistically significant.
Output: method
with 93-100 % agreement for all comparisons.
Output: finding
nutraceutical and ethnomedical uses as well as the biological and pharmacological effects and toxicity of this plant based on 218 literary sources reported over 40 years.
Output: purpose
Interviews and specimens were collected from 565 consenting HCWs.
Output: method
We aimed to describe the frequency and predictors of virus and bacteria codetection in children with ARI and cough , irrespective of clinical diagnosis.
Output: purpose
We describe the case of a healthy man who presented with severe ITP complicated by intracranial haemorrhage following upper respiratory tract infection.
Output: background
MEDI8852 , effectively reacting with all influenza A hemagglutinin ( HA ) subtypes.
Output: purpose
and this study aims to evaluate the long-term results of a spleen-invigorating Huo-Gu Formula ( HGF ) therapy in these patients.
Output: purpose
Quantitative data were to analyze completeness and timeliness of surveillance system performance from national District Health Information System 2 ( DHIS2 ).
Output: method
5 ( 55.6 % ) of the 9 deaths occurred within the third or fourth week.
Output: finding
Aim : To estimate R 0 in nosocomial outbreaks of MERS.
Output: purpose
and the estimated cumulative cases would reach 1514 ( 1384-1656 ) at the tenth day in the future.
Output: finding
Stably transformed Lemna were obtained by co-cultivation with A. tumefaciens EHA105 harboring the PEDV spike protein gene.
Output: method
and recent developments in technologies and policy for detecting and controlling epidemics that have been initiated intentionally.
Output: purpose
with coefficients of variation ( CV ) less than 3.43 and 3.33 % , respectively.
Output: background
Rotavirus likely represses the IFN response by at least 4 mechanisms.
Output: finding
Structurally different from T20 , AP3 could fold into single-helix and interact with gp41 NHR.
Output: finding
and the lay public in understanding the progress of Ebola virus disease and the continuing outbreak.
Output: background
are effective in the prevention of centrogenic PE.
Output: finding
A cross-sectional design was used to analyze data collected between August 2017 and December 2017 from eight hospitals in southern Taiwan.
Output: method
In this study , we determined whether the complex and reactive CNS environment of the mouse hepatitis virus ( MHV ) model of multiple sclerosis ( MS ) could support transplant-mediated remyelination.
Output: purpose
2014 to October 31 , 2014.
Output: method
including from social and economic standpoints.
Output: background
including the variety of life cycles they have developed and the mechanisms by which they have adapted to evolving changes in habitat and host availability.
Output: purpose
in an effort to highlight some of the unanswered questions regarding the coordination of the IAV infection process.
Output: purpose
including administrative , patient , and legal issues.
Output: purpose
Introduction of a CMV promoter upstream of the nsP genes allows direct transfection of plasmid DNA with self-replicating RNA capacity ( 19 ).
Output: method
Here , we will discuss the role of TDP-43 and FUS in SG dynamics and how disease-linked mutations affect this process.
Output: purpose
resulting in a non-productive system in the case of virus outbreaks because early detection and management of the same can become increasingly dependent upon the technological backbone of smart cities.
Output: finding
The seventh novel human infecting Betacoronavirus that causes pneumonia ( 2019 novel coronavirus , 2019-nCoV ) originated in Wuhan , China.
Output: background
derived from 1 - ( x - ( 4-bromophenoxy ) alkyl ) uracil derivatives - previously reported inhibitors of human cytomegalovirus ( HCMV ).
Output: purpose
which is suggestive of a common therapeutic target for both types of enterovirus.
Output: finding
This article reviews what is currently known about the virus and the disease.
Output: purpose
Here , we systematically reviewed studies that performed viral mNGS in common livestock ( cattle , small ruminants , poultry , and pigs ).
Output: purpose
and show that kinetic constants determined from FRET-based assays that are uncorrected for inner-filter effects can lead to artifacts.
Output: finding
Arizona conducted surveillance for severe acute respiratory infections ( SARI ) among adults hospitalized in the Arizona-Mexico border region.
Output: background
Outbreaks of gastroenteritis may lead to serious disruption when many persons are absent from work or school.
Output: background
Nesting material and shelters were used frequently and consistently and allowed animals to display species typical behavior.
Output: finding
although it is much needed for patient contracting the severe form of the disease.
Output: background
A lncRNA discovery pipeline was implemented that identified 15,558 liver-expressed lncRNA genes.
Output: finding
Objective : The purpose of our study was to review the initial high-resolution CT ( HRCT ) findings in pneumonia patients with presumed/laboratory-confirmed novel swine-origin influenza A ( H1N1 ) virus ( S-OIV ) infection and detect pneumonia earlier.
Output: purpose
Using this approach , we demonstrate that mycophenolic acid ( MPA ) can inhibit the GTase reaction by preventing the catalytic transfer of the GMP moiety onto an acceptor RNA.
Output: finding
were cultured in the absence or presence of cadmium ( Cd ) acetate or mercuric ( Hg ) chloride.
Output: method
Employees who attended on-site arrangements had higher influenza vaccination rate ( 97.0 % ).
Output: finding
PDCoV identification was conducted by using a PCR protocol previously described ( 6 ).
Output: method
Analysis of the autoprocessing kinetics in vitro reveals that proteolysis at the Q 2779 - S 2780 site is the first cleavage event mediated by this proteinase.
Output: finding
Background-Respiratory infections are the most common infectious diseases in humans worldwide and are a leading cause of death in children less than 5 years of age.
Output: background
Methods : 33 patients participated in semi-structured interviews.
Output: method
the first step in the preparation of β-amino acids.
Output: purpose
Expression of both the MisL-and 987P subunit FasA-fusions to the TGEV epitopes were under the control of in vivo-induced promoters.
Output: method
leading to a mortality rate of 3.4 %.
Output: background
with a particular focus on systems that achieve good transfection and minimize potential toxicity.
Output: method
It is this group with established asthma in whom acute exacerbations triggered by virus infections remain a serious cause of increased morbidity.
Output: background
and 11 % the risk becoming ill when infected.
Output: finding
Objective : The RDV method was further modified to reduce the candidate PCR primer sets.
Output: purpose
and S. sonnei were assessed to find the most antigenic protein.
Output: method
Direct expression of AXB or BXA produces protein catenanes with distinct ring sizes.
Output: background
Here , we reviewed discovery and development of BSAAs and summarized the information on 119 safe-in-man agents in freely accessible database ( https://drugvirus.info/ ).
Output: method
In this mini-review we give a brief overview of some of the recent trends in computer assisted vaccine development with emphasis on the primary selection procedures of probable peptide candidates for vaccine development.
Output: purpose
( III ) During the COVID-19 epidemic ophthalmologists may have to deal with patients affected by conjunctivitis of other nature and have no guidelines on how to make a differential diagnosis.
Output: background
ABCA1 regulates cellular cholesterol homeostasis.
Output: background
Therefore , a prospective case-control study was conducted to determine the prevalence of respiratory viruses in CRS patients and non-CRS controls.
Output: purpose
We conducted a narrative and tabulated synthesis of the results.
Output: method
the neuropathogenicity of SAFV remains undetermined.
Output: background
In first experiment , 100 adult house flies were divided into control and treatment groups equally.
Output: method
thus providing favorable conditions for virus production.
Output: finding
angiogenesis and other body functions.
Output: background
The aim of this study was to screen a population of 54 cats from Sardinia ( Italy ) for the presence of both FPV and CPV DNA within buffy coat samples using polymerase chain reaction ( PCR ).
Output: purpose
compared with the scenario of no travel restriction.
Output: finding
Here , we elaborated an initial assessment of the impact of TLR9 triggering on EBV-positive and EBV-negative B-cell lymphoma using Burkitt 's lymphoma ( BL ) cell lines as an in vitro model.
Output: method
This paper presents a case-study of news communication regarding the emergence of pH1N1.
Output: purpose
and ( 3 ) review of the current status of rabies and tetanus human vaccine in vitro potency methods for their potential application to the corresponding veterinary vaccines.
Output: finding
the phylogenetic relationships of PEDV strains in the regions of epidemicity in the Philippines to PEDV strains that are endemic in other countries were investigated.
Output: method
This commentary suggests that the growing technology of DNA synthesis should be fully implemented as a means to rapidly generate in vivo data and possibly actionable therapeutics soon after sequence data becomes available.
Output: finding
which may even lead to death.
Output: background
cells ) were constructed.
Output: method
their molecular substrates , and their contributions to disease.
Output: purpose
household contacts , and healthcare personnel.
Output: method
p38 MAPK , c-Fos and c-Jun.
Output: finding
Based on these data , additional clinical trials are in development to evaluate influenza vaccine candidate antigens manufactured using Spodoptera frugiperda ( Sf9 ) / baculovirus-based VLP technology.
Output: finding
For the positive group , samples were selected for the detected viral species.
Output: method
we need a novel therapeutic approach other than EGFR inhibitors.
Output: purpose
by scrubbing the sites using sterile flocked swabs.
Output: method
The current treatment options are limited.
Output: background
Both amplification and spatially resolved signal generation take place on immobilized forward primers bount to expoxysilanized glass surfaces in a pump-driven hybridization chamber.
Output: method
swelling , tenderness , and redness reported in the higher VLP dose groups ( 15 g and 45 g ) compared to the placebo and 5 g VLP groups following both vaccinations.
Output: finding
Rodent health monitoring programs make an essential contribution to biomedical research by identifying the presence of infectious agents that might confound animal research.
Output: background
a b s t r a c t 2-Deoxy-a-D-ribose-1-phosphate is of great interest as it is involved in the biosynthesis and/or catabolic degradation of several nucleoside analogues of biological and therapeutic relevance.
Output: background
or monitored until 14 dpi ( n 2 ).
Output: method
as well as the various etiologies and pathophysiologic mechanisms giving rise to this important disease entity.
Output: method
Comparing the panda pMHC-I to others 21 in the bear family and extending the comparison to other mammals revealed distinct features.
Output: purpose
The aim of the current study was to analyse the effect of both antigen and adjuvant on the cellular and humoral vaccine-induced immune responses by comparing the native ASP to a recombinant version expressed in Pichia pastoris ( pASP ) and replacing QuilA by Al ( OH ) 3.
Output: purpose
The purpose of this study was to analyze the SCUB patterns of the four sequenced cotton species and explore the key factors influencing codon choice.
Output: purpose
it has been known that blood cultures have low yields and rarely affect clinical outcomes.
Output: purpose
but not with increased mental illness.
Output: background
antioxidative and inflammatory parameters in neonatal calves to investigate whether quercetin could compensate for insufficient colostrum supply.
Output: purpose
we evaluated pathogenicity by using a new premature reproductive tract pathogenicity model.
Output: method
The severity of a patient 's illness was assessed by chart review post-discharge looking for clinical markers of respiratory status such as presenting symptoms , diagnoses , and interventions.
Output: method
RV-specific sequences were identified by partial sequencing of VP4/VP2 and 5 ′ non-coding regions with 80 % success rate.
Output: method
more than 70 % and 90 % of contacts respectively had to be traced to control the majority of outbreaks.
Output: finding
recent studies indicate it may represent a combination of immune responses.
Output: background
mechanically interlocking SpyX modules named AXB and BXA.
Output: background
retrotranscription polymerase , Monoplex polymerase chain reaction ( PCR ) and Multiplex PCR.
Output: method
the area under the ROC curve was 0.86 ( 95 % CI 0.75-0.97 ) and setting sensitivity at 86 % gave specificity of 71 %.
Output: finding
Cyclophosphamide was used to immunosuppress hamsters leading to a prolonged disease course and higher mortality after SARS-CoV infection.
Output: method
The aim of this study is to investigate the expression of cytokines in AECOPD.
Output: purpose
The effects of face mask wearing were investigated using multilevel ( hierarchical ) modelling.
Output: method
This review focuses on technological advances which allow this interaction to be studied in much greater detail.
Output: purpose
We developed a testing algorithm for high throughput screening of livestock sera with ELISA and confirmation with recombinant immunofluorescence assay testing for antibodies against HCoV-NL63 in livestock.
Output: method
including many cancers , autoimmune , metabolic and infectious diseases.
Output: background
conjunctivitis , diarrhoea and outbreaks have been reported.
Output: background
others might highly depend on the particular ward structure under study.
Output: purpose
in the Serengeti National Park , Tanzania.
Output: purpose
Albuquerque UP ( 2019 ) Adaptive memory and evolution of the human naturalistic mind : Insights from the use of medicinal plants.
Output: finding
come in different sizes , shapes and symmetries.
Output: background
sequenced , and compared with other TGEV strains genes selected from the GenBank.
Output: method
including an indirect ELISA ( iELISA ) ; a highly specific monoclonal antibody-based blocking ELISA ( bELISA ) ; fluorescent microsphere immunoassays ( FMIA ) that can be multiplexed to monitor exposure to multiple antigens and pathogens simultaneously ; and a fluorescent focus neutralization assay ( FFN ) to measure functional virus neutralizing antibodies.
Output: purpose
MERS-CoV continues to be an endemic , low-level public health threat.
Output: background
the only vesicle that was fused by DV fusion peptide.
Output: method
The analytical sensitivity of the EEDV-LAMP method was estimated to be as low as 16 copies of plasmid per reaction.
Output: finding
In this study , three effective siRNAs targeting NS3 of CSFV were selected.
Output: method
Mutants were expressed in COS or 293T cells and assayed for cell surface expression and structural features as well as for their ability to change conformation and induce fusion at low pH. We found the following : Specific mutations affected the precise carbohydrate structure and folding of the HA trimer.
Output: method
Meanwhile , iPSC-nCoVN lost the ability for differentiation into cardiomyocytes when using a routine differentiation protocol.
Output: finding
Echinococcus multilocularis and Baylisascaris spp. ).
Output: finding
sensitive , multiplex discrimination of microbial gene sequences and report its application for detecting 22 respiratory pathogens in clinical samples.
Output: purpose
and the mCAT-1 transfectants did not show the relative resistance of NIH 3T3 cells to Spl574.
Output: finding
as well as hand hygiene compliance rates.
Output: method
including intravenous ( IV ) ceftriaxone , azithromycin , and linezolid.
Output: background
We give examples of the Cavbase similarity analysis detecting pronounced similarities in the binding sites of proteins unrelated in sequence.
Output: method
The gram-negative coccobacillus now designated as Yersinia pestis has been discovered as the causative agent of plague in this Hong Kong outbreak.
Output: background
We cite recent examples of virus emergence that exemplify how arboviruses have exploited the consequences of the modern human lifestyle.
Output: method
factors that may place healthcare workers at higher risk for infection.
Output: finding
On Western blots , 40 cercarial and 7 schistosomular antigens were recognized by IgY from infected ducks.
Output: finding
An unpaired t-test was used for statistical analysis of the drugs ' effects.
Output: method
we speculate that this building principle is a blueprint for cell-surface architectures utilized by viral particles.
Output: purpose
Administered drugs and intervention times were compared in 47 and eight patients with mild and severe symptoms , respectively.
Output: method
Therefore , the present case-control study aimed to determine the levels of 90 IL-1 family ( IL-1β , IL-37 ) and IL-12 family ( IL-12 , IL-35 ) in these patients and the 91 association between these cytokines levels and the patients ' demographic 92 characteristics.
Output: purpose
bites and scratches from bats and the use of bats for food , medicinal or ritual purposes.
Output: method
The objective of this study was to explore the use and perceptions of a local Severe Acute Respiratory Syndrome ( SARS ) Extranet and its potential to support future information and communication applications.
Output: purpose
The RNA guanylyltransferase ( GTase ) is involved in the synthesis of the m7 Gppp-RNA cap structure found at the 59 end of eukaryotic mRNAs.
Output: background
The viruses associated with acquired immunodeficiency syndrome and hepatitis are also discussed.
Output: finding
Correlation analysis of mean SMK of 708 case study residential units determined by the detailed computer simulation method and the corresponding angle of unobstructed sky showed that the latter can be used to assess view obstruction adequately close to simulation predictions.
Output: finding
This difference in timing between these 2 groups was significant ( P = .004 ).
Output: finding
For this study , we determined the genome sequences of BYD1 and the S1 gene sequences of other five mammalian reovirus isolates ( BLD , JP , and BYL were isolated from different SARS patients during the outbreak , 302I and 302II were isolated from fecal specimens of two children of Beijing in 1982 ) to allow molecular comparison with other previously reported mammalian reoviruses ( MRVs ).
Output: purpose
Reads were processed using Mothur and QIIME pipelines and assigned 12,345 OTUs for C1 and 5,408 OTUs for C2.
Output: method
we screened a library of F. tularensis subsp. tularensis Schu S4 HimarFT transposon mutants in GFP-LC3-expressing murine macrophages by microscopy for clones localised within autophagic vacuoles after phagosomal escape.
Output: method
which is observed for hydrogen peroxide.
Output: finding
National guidelines recommend that healthcare workers ( HCW ) who use N95 masks require fit testing.
Output: background
Currently , RT-PCR is a reliable test in detecting both symptomatic and asymptomatic COVID-19.
Output: finding
Persistence of CDV in the brain appears to be due to non-cytolytic selective spread of the virus with very limited budding.
Output: finding
was used to assess specificity in acute cases.
Output: method
which can be used to understand the contribution of host genetics to vaccine efficacy.
Output: method
Capillary electrophoresis indicated that DON at concentrations as low as 200 ng/ml evoked selective rRNA cleavage after 6 h and that 1000 ng/ml caused cleavage within 2 h. Northern blot analysis revealed that DON exposure induced six rRNA cleavage fragments from 28S rRNA and five fragments from 18S rRNA.
Output: method
Plasma membrane cholesterol was depleted from common carp brain ( CCB ) cells with methyl-b-cyclodextrin ( MbCD ).
Output: method
Examination of practical , theoretical and methodological values of findings includes considering research needed and the utility of safety measure information in business decision making.
Output: finding
After a disaster , our society requires resilience to return to normalcy following the disaster 's physical and social impact.
Output: background
We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus.
Output: method
as illustrated with the chosen examples from the literature.
Output: finding
and technical issues in relation to commonly used approaches to surveillance.
Output: purpose
We recently introduced Cavbase , a method for describing and comparing protein binding pockets on the basis of the geometrical and physicochemical properties of their active sites.
Output: method
Thermodynamic model for the performance estimation of the combined system is investigated.
Output: method
Each author should submit a separate form and is responsible for the accuracy and completeness of the submitted information.
Output: method
We investigated the clinical characteristics of COVID-19 patients with AMI and determined the risk factors for AMI in them.
Output: purpose
This review provides the latest update on the interplay between human host factors/processes and non-polio enteroviruses ( NPEV ).
Output: purpose
Here , we show that the host response to a single JHMVspecific immunodominant CD4 T-cell epitope is critical for severe disease.
Output: purpose
We provide an overview of the current status of HEV antiviral research.
Output: purpose
and operon structures , thus improving the structural annotation in bacteria.
Output: background
while the oxygenation index levels were below normal and continued to decline in the fatality group.
Output: finding
which causes 0.8 million deaths a year.
Output: background
The study of HCoV-host interactions has contributed extensively to our understanding of HCoV pathogenesis.
Output: background
stimulation with lipopolysaccharide ( LPS ) induced the production of biologically active interleukin 1.
Output: finding
and likelihood a patient could be infected based on symptoms and testing.
Output: method
consistent with attenuation by slower growth as opposed to reduced mutational supply.
Output: finding
Nonetheless , the intriguing HBV genome has not been well characterized.
Output: background
laboratory samples and methods and identified pathogens.
Output: method
suggesting that E palmitoylation modification or disulfide bond formation is not required for SARS-CoV virus assembly.
Output: finding
A cluster tree was developed from the profiles retrieved from the presence and absence of homologs of ten 2019-nCoV proteins.
Output: method
and virus detection was performed by polymerase chain reaction.
Output: method
anticipatory disaster stress , and motivation for disaster engagement.
Output: purpose
The papain-like cysteine proteases encoded by the coronavirus ( SARS-CoV : PLpro ; NL63 : PLP1 and PLP2 ) represent potential targets for antiviral drug development.
Output: background
Interviewees were observed donning and doffing an N-95 respirator as they normally would during patient care.
Output: method
indicating that OAS1 dysfunction is associated with impaired surfactant catabolism due to the defects in AMs.
Output: finding
Here , we investigated whether HCoV-EMC and SARS-CoV induce similar or distinct host responses after infection of a human lung epithelial cell line.
Output: purpose
Acute bacterial sinusitis is a frequent complication of viral upper respiratory infection ( URI ).
Output: background
including substrate binding mode and coordination of the nucleophilic water molecule.
Output: finding
this review highlights some of the controversies regarding the implementation and efficacy of these interventions.
Output: purpose
Ten patients were admitted to the designated hospital.
Output: method
We simplified the scenario by dividing each indoor environment into different sub-visiting locations that represent different time durations for visiting each indoor environment.
Output: method
On day 5 , the physician who had performed intubation presented with numerous furuncles of the fingers and face.
Output: finding
This review describes our current understanding of potential APCs in the CNS and the contribution of these and other CNS-resident cells to disease pathology.
Output: finding
The 68K '' '' protein was also detected on the surface of metabolically labeled BALB/cV tumor cells by an external immunoprecipitation technique.
Output: finding
The goal was to produce in as little as one week thousands of doses of an intervention for a new pathogen.
Output: purpose
Concern about its associated morbidity and cost has led to a large body of research that has been summarised in systematic reviews and integrated into clinical practice guidelines in several countries.
Output: background
particularly among natural colonies of bats.
Output: background
Later still necrosis develops.
Output: background
utilising a diagnostic strategy incorporating molecular testing.
Output: purpose
Viral infections play several different roles in asthma in childhood.
Output: finding
we investigated the combination of IFN-b and ribavirin.
Output: method
exfoliated enterocytes , and parasitic worms.
Output: finding
The characterization of the responses of target cells to ZEBOV infection may therefore not only further understanding of pathogenesis but also suggest possible points of therapeutic intervention.
Output: purpose
We argue that disease-related news ( DRNs ) should not trigger rational trading.
Output: method
The phylogenetic relationship between the isolated magnetic strains and some known magnetotactic bacteria was inferred by the construction of phylogenetic tree based on 16SrDNA sequences.
Output: method
a sulfated glycan , less efficiently than wild-type CVB3 did.
Output: finding
Here , we investigated the antiviral activity of MBL in infection by dengue virus ( DENV ) , a related flavivirus.
Output: purpose
2H phosphoesterases catalyze reactions on nucleotide substrates and contain two conserved histidine residues in the active site.
Output: background
There were 7 pens/diet with 11 pigs/pen and 8 pens/diet with 31 pigs/pen.
Output: method
We have tried to disrupt this helical conformation by mutating L141 to T in the stable inactive monomer G11A/R298A/Q299A.
Output: method
and South AfricaÕs increasingly prominent political and commercial role in Africa.
Output: background
Additionally , NQ 4 disrupted the viral attachment of HHV-1 to Vero cells ( EC 50 : 0.12 µg/mL , 0.38 µM ) with a very high selectivity index ( SI = 1728 ).
Output: finding
This case highlights the necessity for health care workers to protect themselves against transmission of infectious diseases from patient to care giver.
Output: background
cesarean-derived , colostrum-deprived ( CDCD ) piglets.
Output: method
Approximately half the reports on protein microarrays have been published in the last two years especially in the area of biomarker discovery.
Output: background
with peak positivity at ages 5-9 years.
Output: finding
characterization of cell tropism , and how to perform antiviral assays and quantify viral replication.
Output: purpose
These increased yields provide sufficient quantities of active enzyme for use in NMR-based ligand mapping.
Output: background
Discussions on disaster resilience have been increasing in recent years.
Output: background
Memorizing medicinal plants for the treatment of serious diseases likely maximized the chances of survival and reproduction and was instrumental in the evolutionary success of our species.
Output: background
the implementation of such approaches in low-and middle-income countries ( LMICs ) is often restricted due to limited resources and underdeveloped infrastructure.
Output: background
by cataloguing genomic features for strain discrimination and by observing clinical features in positive patients.
Output: purpose
The sensitivity and specificity of the newly developed LAMP assay compared to the SYBR Green qPCR assay were 84.3 % and 93.3 % , respectively.
Output: finding
with relevant samples collected to assess virus infection and antiviral responses.
Output: method
whereupon analysis can take place.
Output: background
This study analysed the consequences of deviation from the WHO case definition for the assessment of patients with suspected severe acute respiratory syndrome ( SARS ) in The Netherlands during 2003.
Output: purpose
The isolated protein product contains the brazzein domain folded with correct disulfide bonds formed and is then cleaved with a specific SUMO protease to liberate native brazzein.
Output: finding
causes acute diarrhoea and dehydration in pigs.
Output: background
Our purpose is to demonstrate the importance of mathematical modelling for the understanding and management of infectious disease transmission.
Output: purpose
Findings PLANET relies on real-time information from three levels of participants in large-scale programs : funders , managers and recipients.
Output: background
this perturbation may protect DENV and related viruses from innate immunity and create a favorable replicative environment.
Output: finding
Additional evidence for the pivotal role of extracellular cysteines in the APN molecule was obtained when substitution of any of these six cysteines caused complete loss of surface expression and enzymatic activity.
Output: finding
Here , we develop mathematical models with multiple infection stages and estimate parameters based on within-host data to investigate the impact of behavior change on influenza dynamics.
Output: purpose
paediatric , emergency/Intensive medication wards.
Output: method
the study of host response and immunopathogenesis is difficult.
Output: background
N63Y mutant CVB3 may be useful as a platform to understand viral adaptation and pathogenesis in animal studies.
Output: finding
and this cytopathic response was accompanied by the accumulation of unintegrated viral DNA.
Output: finding
Diarrhea is one of the most common causes of antimicrobial use and mortality in young calves.
Output: background
operate and analyze moving objects ' relationships and introduces two algorithms ( relationship querying and relative relationship dynamic pattern matching ) to derive and analyze the dynamic relationships of moving objects.
Output: purpose
Massachusetts and QX-like strains showed different cleavage site motifs.
Output: finding
Both proteins contain a single transmembrane-spanning segment but are integrated in the membrane with opposite orientations.
Output: background
Objectives : To determine the viruses associated with ALRI among children living in the PNG highlands using sensitive molecular detection techniques.
Output: purpose