niryuu/sni-each-converted huggingface dataset:
Epithelia exposed to 95 % oxygen plus 1 ppm ozone were stratified and nonciliated or very sparsely ciliated.
Output: finding
identifying four possible reasons for the slow development of an effective protocol and describing eight future directions to improve the current protocols.
Output: purpose
including the catalytic Cys25 and His162.
Output: finding
the HR1 fragment binds to HR2 to form a six-helix bundle with three HR1 fragments forming the central coiled bundle surrounded by three coiled HR2 fragments in the post fusion conformational state ( fusion core ).
Output: background
using Great Britain and the United States as examples.
Output: method
similar to brown bat endogenous retrovirus ( FERVmlu1 , FERVmlu2 ) were found within a 140 Kbp interval in the middle of class I region.
Output: finding
On average , these pathogens share little sequence similarity and use different replication and transcription strategies.
Output: background
The present study focuses on the neuroprotective effect of glycyrrhizic acid ( GA , a major compound separated from Glycyrrhiza Radix , which is a crude Chinese traditional drug ) against glutamate-induced cytotoxicity in differentiated PC12 ( DPC12 ) cells.
Output: purpose
A field experimental study was designed with the QAC plus daily hypochlorite cleaning as the experimental group and hypochlorite cleaning alone as the control group.
Output: method
leading to central sympathetic activation that results in systemic vasoconstriction.
Output: finding
I outline a framework that uses specific molecular characteristics to rank virus families by their expected a priori ability to complete each of three steps in the emergence process ( encounter , infection , and propagation ).
Output: method
it ultimately provides molecular epidemiological data from polioviruses used to inform programmatic and immunization activities.
Output: purpose
house detergent , and a peroxygen compound ( Virkon S ; Antec International ) on the virus were also studied.
Output: method
Experimental assays show that titanium containing polyoxotungstates have anti-influenza-virus activity.
Output: background
Biases are therefore imbedded in surveillance systems ; these biases need to be characterized to provide better situational awareness for decision-making purposes.
Output: background
Objectives-Identify candidate pathogens in pediatric patients with unexplained respiratory disease.
Output: purpose
The profile of the fecal bacterial microbiota was compared using 16S amplicon sequencing.
Output: method
2013 , and June 3 , 2013.
Output: method
and response measures for the primary eye care provider.
Output: purpose
and conjugated with rAzu to develop a general platform for electrochemical detection of miRNAs and viral DNAs with high reproducibility and ultra-sensitivity towards single base pair mutation.
Output: method
we generated recombinant MP-12 encoding Punta Toro virus Adames strain NSs ( rMP12-PTNSs ) or Sandfly fever Sicilian virus NSs ( rMP12-SFSNSs ) in place of MP-12 NSs.
Output: method
Transcription of hepatitis B virus ( HBV ) from the covalently closed circular DNA ( cccDNA ) template is essential for its replication.
Output: background
The biologic function of this cell surface-expressed viral protein remains unknown.
Output: finding
Chronic cough patients also underwent cough reflex sensitivity testing using citric acid.
Output: method
In this study , the altered genes expressions in the PBMC of convalescent SARS patients were investigated with suppression subtractive hybridization ( SSH ).
Output: background
ribavirin , and intravenous immunoglobulin were higher in the SARS group.
Output: finding
Thus , several locations may represent the same indoor environment at a different time.
Output: method
we include examples from our own work that are intended to provide insights into the process that led to the selection of particular strategies.
Output: method
More recently , a different cell model and the focus on the water soluble fraction of the extract led to the discovery of other compounds.
Output: background
Nasal samples were obtained during 4 asymptomatic surveillance visits and during symptomatic URIs.
Output: method
numerous model predictions on the COVID-19 epidemics in Wuhan and other parts of China have been reported.
Output: background
publicly funded repositories , such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source.
Output: background
1 This article presents an overview of the PHS and how Commissioned Corps officers respond during times of national and global need.
Output: purpose
perhaps through activation of NF-κB.
Output: background
Particularly , the models can help identify potential adverse effects of vaccination and drug treatment in the case of pandemic influenza.
Output: finding
the nucleocapsid protein of SARS-CoV-2 ( nCoVN ) functions in packaging the viral genome and viral self-assembly.
Output: background
We undertook a sentinel event strategy ( where single health events signal emerging trends ) to estimate the incidence of COVID-19 in the US.
Output: purpose
PAM-pCD163 , and tested for its potential to inhibit IFN-b induction.
Output: method
is dependent upon a stem-loop structure beginning 14 nt downstream of the slippery site.
Output: finding
plasma IgG , and lymphocyte counts were not affected by treatment.
Output: method
The evolutionary history was computed by using Tamura-Nei model with 1 000 replicates of bootstrap analysis.
Output: method
Here , we take a step toward this vision by developing an approach that couples isothermal amplification of specific plant pathogen genomic sequences with customizable synthetic RNA regulators that are designed to trigger the production of a colorimetric output in cell-free gene expression reactions.
Output: purpose
View obstruction level and the applicable premium are useful information for stakeholders of the property market for making optimum decisions.
Output: background
A novel air dehumidification system is proposed.
Output: purpose
we performed viral metagenomics to assess other potential viral pathogens.
Output: method
Background : The population of dogs and cats passing through rescue shelters may be subject to compromised welfare and increased susceptibility to disease.
Output: background
Objective : We tested the hypothesis that medical students receive insufficient training on correct methods for donning and doffing PPE.
Output: purpose
The effects of oral immunization of CpG DNA together with inactivated TGEV ( ITGEV ) were investigated in this study.
Output: purpose
We evaluated the proposed method over a number of spatial and spatio-temporal datasets ( Breast cancer mortality in Northeastern US 1988-1992 and different types of cancer in New Mexico 1982 -2007.
Output: method
and the relationship between those depressive symptom levels and the types of outbreak event exposures experienced.
Output: purpose
F and G were identified.
Output: finding
with onset of illness in the same 10-day period.
Output: background
The overall clinical score corresponded well with the shedding of viral RNA the first three weeks after challenge.
Output: finding
This review discusses emerging evidence for the diversity of this fascinating group of membrane serine proteases as potent modifiers of the pericellular microenvironment through proteolytic processing of diverse substrates.
Output: purpose
It is of crucial importance to estimate the reproductive number ( R0 ) of the novel virus in the early stage of outbreak and make a prediction of daily new cases on the ship.
Output: background
The aim of the present work was to study if maternal IgG1 antibodies ( Abs ) to BCoV acquired by colostrum intake modulate the development of BCoV infection in calves reared in a dairy farm in Argentina.
Output: purpose
so unbiased metagenomic sequencing was performed.
Output: method
in turn , carry out effector functions that serve to protect or destroy.
Output: background
Flanking sequences were standardized by head-to-tail insertion of several copies of an RNA7 body TRS cassette.
Output: method
which has been linked to a wide range of human health and disease states , including viral infection.
Output: background
leading to an increase of positive charge on C ( CO ) of Gln and negative charge on N ( NH ) of Ser.
Output: background
We conducted a nationwide inpatient cohort study based on the Taiwan National Health Insurance Research Database between 1997 and 2011.
Output: method
and we compare viruses identified at the time of diagnosis of sinusitis with those identified early in the URI.
Output: purpose
In this review , we will discuss recent advances in our understanding of yeast and mammalian TRAPP at the structural and functional levels and its role in disease while trying to resolve some apparent discrepancies and highlighting areas for future study.
Output: purpose
Aa-tRNAs were precipitated with ethanol and dissolved in water ; concentrations were determined photometrically by absorbance at 260 nm.
Output: method
gallotannins were identified in the banaba extract as components responsible for the activity , not corosolic acid.
Output: background
although at a lower level compared to M , N and E co-expression.
Output: background
Mice were orally treated for 9 consecutive days starting on the day of infection with daily ATA doses of 50 and 100 mmol/kg.
Output: method
9th edition code and identification of only patients with more severe ARDS in this analysis.
Output: finding
further revealed that translational selection played the dominant role over mutation pressure in the codon usage bias.
Output: finding
transmission of MERS-CoV is geographically limited ( 12 ).
Output: background
The data were analysed on the basis of the constructivist version of grounded theory.
Output: method
and low likelihood of sustainability beyond the end of the program ' s implementation.
Output: background
Case report We report a case of acute respiratory distress syndrome ( ARDS ) complicating severe EBV pneumonia and requiring prolonged artificial ventilation.
Output: purpose
marital status and education level.
Output: purpose
We propose a feasibility study to demonstrate our ability to recruit and retain patients and conduct a placebocontrolled trial of Pelargonium sidoides extract EPs ® 7630 in lower respiratory tract infection where pneumonia is not suspected.
Output: purpose
We report a molecular method allowing for the detection of HCoV-HKU1 and also report the clinical presentation of 6 infected patients.
Output: purpose
The compound 19 was the best and showed comparable MICs to the known compound karanjin.
Output: finding
splicing , turnover , and protein synthesis.
Output: background
and made it possible to investigate SCUB patterns in cotton nuclear and organelle genomes.
Output: background
viperin , was overexpressed in A549 cells resulting in a significant reduction in viral replication.
Output: finding
We have studied the inhibitory properties of aurintricarboxylic acid ( ATA ) against YopH phosphatase and found that at nanomolar concentrations ATA reversibly decreases the activity of YopH.
Output: finding
Here , this attachment molecule was identified as heparan sulfate for both Nipah virus and Hendra virus.
Output: finding
At the same time , the results of a recent dromedary camel embryo transfer study which produced a high morphologic integrity and survival rate of Open Pulled Straw-vitrified embryos are also discussed.
Output: purpose
Monoclonal antibody isolation was perfomed as previously described ( Pappas et al. , 2014 ; Traggiai et al. , 2004 ).
Output: method
are critical for host survival.
Output: background
The SARS-coronavirus ( SARS-CoV ) is the etiological agent of the severe acute respiratory syndrome ( SARS ).
Output: background
undue avoidance of governmental structures / preference to non-governmental organizations and exclusion of local expertise.
Output: background
they have been associated with illnesses that require hospitalization.
Output: background
has been implicated as a major factor in Alzheimer 's disease ( AD ).
Output: background
Demographic data were used to link SARI patients to Arizona death certificates.
Output: method
The histopathological picture as well as the laboratory findings suggests a viral cause of the disease.
Output: finding
continuously spurred by our never-ending combat against pathogens.
Output: background
and from each , six to eight sampling sites were visited.
Output: method
The biomarkers were also examined in children admitted with acute bronchiolitis serving as positive controls ( N = 30 ) and in age-matched controls ( N = 20 ).
Output: method
We demonstrated that changes in reporting rate substantially affect estimates of R 0.
Output: finding
VP3 N63Y , that was sufficient for large-plaque formation.
Output: finding
particularly if safety precautions are not rigorously practiced.
Output: background
modulation of immunity , and production of bioactive compounds.
Output: background
The cyclic voltammetry experiments suggest that ATA reacts remarkably strongly with molecular oxygen.
Output: finding
The main objective was to report real-time effective reproduction numbers ( R ( t ) ) case fatality rate ( CFR ).
Output: purpose
and psoriasis , we investigated inflammatory skin disease in transgenic mice that constitutively overexpress human TGF-β1 in basal keratinocytes ( K5.hTGF-β1 transgenic mice ) ; these mice had previously been reported as having a psoriasis-like disease.
Output: purpose
Western analysis , use of glycosylation inhibitors and mutagenesis to remove receptor glycosylation sites identified a possible role for cell-specific glycosylation in the modulation of virus entry.
Output: finding
HEK 293 cells were transiently transfected with full-length wild type HA expressing plasmids.
Output: method
In conclusion , these attenuated vaccines have potential for controlling local Taiwanese IBV infections in chickens.
Output: finding
The patient had eaten no recent restaurant foods and had no known sick contacts.
Output: background
The aim of this study was to introduce Alphitobius diaperinus as a new intermediate host for Hadjelia truncata.
Output: purpose
different cells , and various proteins that protect the host from pathogens.
Output: background
based on disease progression and response to treatments.
Output: method
In contrast , NO synthase ( NOS ) inhibitors reverse such lung injury.
Output: finding
activation and function of different lymphocyte subsets.
Output: purpose
In this article , we describe application of an infectious clone system for DENV serotype 1 ( DENV1 ).
Output: purpose
corosolic acid was isolated from the methanol extract of banaba and shown to be an active compound.
Output: background
but the regulatory functions of CTSL on mucosal immune responses have n't been tested and remain undefined.
Output: background
This protocol represents an important advancement that will enable more efficient research into the interaction between brazzein and the receptor as well as investigations to test the potential of brazzein as a commercially viable natural low calorie sweetener.
Output: finding
processes and outputs and applies them into the 2003 SARS and MERS outbreak in South Korea.
Output: method
G. abietina , though they might have had an innocuous ancestral relationship.
Output: finding
we find that within-host spread is associated with viral replicative speed and not standing genetic diversity.
Output: finding
We studied the spatial distributions of simulated virus-laden respiratory droplets when human subjects wore facemasks and were exposed to regulatory viral droplets by conducting in vivo experiments in facemask use.
Output: purpose
The virus probes are used not only to identify known viruses but also for discerning the genera of emerging or uncharacterized ones.
Output: method
The study comprised 67 patients with skin or mucous membrane lesions suggestive of herpes simplex virus ( HSV ) infection.
Output: method
This study used the Technology Acceptance Model ( TAM ) to examine taxpayers ' acceptance of the Internet tax-filing system.
Output: purpose
is used for the assessment of the influence of LCCs on the South Korean and airline industry.
Output: method
also exhibits considerable oncolytic activity against mammalian cancers.
Output: background
The synonymous codons are not used at equal frequencies in coding sequences in many organisms ( 1 ).
Output: background
This work explores how protein states can be manipulated through controllability analysis : the determination of the minimum manipulation needed to drive the cell system to any desired state.
Output: purpose
This study explores the impact of domestic low-cost carriers ( LCCs ) on regional tourism and aviation industries.
Output: purpose
Relevant research is reviewed , and policy options are discussed.
Output: finding
Seventy-five peptide sequences were modelled and their MHC class I molecule-binding abilities were analysed by molecular docking.
Output: method
thereby providing more possible cooperation in the case of disasters.
Output: finding
The spinal cord and its leptomeninges were involved to a lesser degree.
Output: finding
The amplicon is labeled during on-chip RPA by reverse oligonucleotide primers coupled to a fluorophore.
Output: method
Its incidence is estimated at 75 cases per 100,000 population and appears to be increasing ( 1 ).
Output: background
The severe acute respiratory syndrome ( SARS ) coronavirus ( CoV ) was identified as the etiological agent of an acute respiratory disease causing atypical pneumonia and diarrhea with high mortality.
Output: background
Realistic surveillance simulations may prove invaluable to optimize system design and tuning.
Output: finding
Conclusion : The study demonstrated that spike glycoprotein of the Massachusetts and the QX-like variants of IBV are molecularly distinct and that this may reflect in differences in the behavior of these viruses in vivo.
Output: finding
This chapter summarizes and reviews nonviral DNA delivery for both gene therapy and DNA vaccination in the lung.
Output: purpose
prior to purification , to yield an N-terminally His 6 - tagged protein.
Output: method
To examine coxsackievirus pathogenesis , we orally inoculated mice with the coxsackievirus B3 ( CVB3 ) Nancy strain.
Output: method
In particular , the identification of non-coding RNAs has revealed their widespread occurrence and functional importance in gene regulation , stress and virulence.
Output: background
in our experimental settings , MyD88 is redundant for IFN-I responses and overall defense against a systemic herpes virus infection.
Output: finding
and how these processes orchestrate and govern cell fate upon viral infection.
Output: finding
The objectives of this study were to evaluate the effects of free-access acidified milk replacer feeding on the pre-and postweaning health of dairy and veal calves.
Output: purpose
The applicability in immunodiagnostics was statistically evaluated by expression of specificity and sensitivity values for individual antigens.
Output: method
improve food safety and reduce outbreak impacts.
Output: purpose
alongside genomic data and temporal data.
Output: purpose
Deletion mapping experiments identified two domains responsible for the speckle formation in MHV EGFP-nsp15 : Domain I ( aa101-150 ) and Domain III ( aa301-374 ).
Output: finding
In this study , we report the interaction of a SARS-CoV 7a and small glutamine-rich tetratricopeptide repeat-containing protein ( SGT ).
Output: purpose
In addition CCSP promoter is commonly used to direct gene expression into the lung in transgenic models.
Output: background
The two best final models were selected : one with and one without NS1 rapid test result.
Output: method
α-synuclein and human amylin , and introduce a small number of peptides that have been shown to be capable of inhibiting the amyloidogenesis of both of these very dissimilar polypeptides.
Output: purpose
Background : The cause of severe disease in some patients infected with pandemic influenza A virus is unclear.
Output: background
N63Y , in the VP3 capsid protein that was sufficient to confer the large-plaque phenotype.
Output: finding
the onset of severe acute respiratory syndrome coronavirus ( SARS-CoV ) and Middle East respiratory syndrome coronavirus ( MERS-CoV ) have thrust HCoVs into spotlight of the research community due to their high pathogenicity in humans.
Output: background
focusing specifically on infectious diseases by examining cases of outbreaks of infectious diseases that have occurred in Korea.
Output: purpose
though eventually it spread to five continents.
Output: background
In this study , we report a single nucleotide resolution transcriptome map of H. somni strain 2336 using RNA-Seq method.
Output: purpose
A Bayesian hierarchical statistical model was developed to examine the statistical relationships between the influenza surveillance data and the information environment represented by alerts from HealthMap and web queries from Google.
Output: method
Lung suspensions and BAL fluids were titrated for PRRSV.
Output: method
to be used throughout the interventional platform.
Output: method
In addition , the efficacy and side effects of NM in cancer patients are summarized in detail.
Output: purpose
which is rationalized by the arrangement of three domains in space.
Output: finding
characterize CC1 mAb binding , and evaluate CC1 in syngeneic mouse oncology models as a monotherapy and in combination with an anti-PD-1 mAb.
Output: purpose
Methods : Groups of 35 domestic ducks and 10 mallards were exposed to different doses of T. regenti cercariae.
Output: method
using a viral gene chip to identify viral DNA or RNA.
Output: purpose
We evaluated the effectiveness of exit and entry screening for 2019-nCoV infection.
Output: purpose
or in combination with the removal of six additional genes nonessential for virus replication.
Output: background
Moreover , other studies outlined factors influencing disaster management and response from a macroscopic perspective and analyzed disaster management and response through awareness surveys ( 8 , ( 12 ) ( 13 ) ( 14 ).
Output: background
and lung ultrasonography was performed.
Output: method
and a discrete time delay for the incubation period in disease transmission.
Output: purpose
Purpose : To assess 2009 H1N1 and seasonal influenza vaccination coverage and identify factors independently associated with vaccination among HCP in the U.S. Methods : Data from the 2009 -2010 Behavioral Risk Factor Surveillance System ( BRFSS ) influenza supplemental survey were analyzed in 2011.
Output: purpose
We conclude with a discussion of the need for public health to expand its horizon and tear down the walls of the silos that inhibit the emergence of relevant global public health.
Output: finding
This enzyme has been shown to be active as a dimer in which only one protomer is active.
Output: background
Oligonucleotides were purchased from Invitrogen.
Output: method
The results indicated that , compounds 5c and 5i exhibited the most potent antibacterial activity.
Output: finding
Kn2-7 could inhibit all members of a standard reference panel of HIV-1 subtype B pseudotyped virus ( PV ) with CCR5-tropic and CXCR4tropic NL4-3 PV strain.
Output: finding
Here , we present a novel approach for treating SCID that combines selective depletion of GvHD-inducing alpha/beta ( α/β ) T-cells from the haploidentical HSCT graft with a subsequent donor lymphocyte infusion ( DLI ) enriched for CD45RO + memory T-cells.
Output: purpose
and NMR data on the conformational states of the N-terminal domain ( SUD-N ) and the SUD-NM two-domain construct.
Output: purpose
using tropism infection and innate immunologic assays.
Output: method
We tested the role of the `` spring-loaded '' conformational change in the fusion mechanism of the influenza hemagglutinin ( HA ) by assessing the effects of 10 point mutants in the region of high coiled-coil propensity , HA2 54-81.
Output: method
and investigated whether MBL deficiency and MBL2 polymorphisms are associated with schistosomiasis.
Output: method
and critical PCO 2 ≥ 60 mm Hg.
Output: finding
using E. coli DNA polymerase III as a conceptual framework ; and 3 ) the promise of genetic and therapeutic interference with fidelity regulation as an approach for attenuation and treatment of CoVs.
Output: purpose
General agreement exists effective disaster management faces constraints related to knowledge sharing and a need for real-time research responses.
Output: background
Only two HCW involved in different clusters , reported pneumonia.
Output: finding
SNAP and RAPSearch , which are as accurate as existing bioinformatics tools but orders of magnitude faster in performance.
Output: finding
Healthcare settings have played a major role in propagation of Ebola virus ( EBOV ) outbreaks.
Output: background
39 Quality Control measures 40 A known amount of whole equine herpesvirus ( EHV ) spiked into each sample assessed nucleic 41 acid extraction quality and presence of polymerase chain reaction ( PCR ) inhibitors.
Output: method
at any of several intervals relative to ovalbumin ( OVA ) administration resulted in elevated OVA-specific IgG 2 a titers.
Output: background
In this context , controllability analyses aim to identify key regulating host factors of the infected cell 's progression.
Output: purpose
designated Z2 , potently inhibits infection of ZIKV and other flaviviruses in vitro.
Output: purpose
Polyoxometalate ( POM ) has promising antiviral activities.
Output: background
HMA has become an important target in the treatment of type-2 diabetes.
Output: background
The low pH environment of the endosome facilitates passage of the viral genome into the cytoplasm.
Output: background
a factor neglected by some previous studies because of their reliance on what A.O.Hirschman ( 1970 ) termed `` paradigmatic thinking ''.
Output: purpose
animal , and environmental samples.
Output: background
Background : The potential risks associated with `` toilet plume '' aerosols produced by flush toilets is a subject of continuing study.
Output: background
Existing methods based on free energy minimization tend to be very slow and are limited in the types of pseudoknots that they can predict.
Output: background
together with nucleotide binding , imposes a rigid intertwined dimer configuration that is essential for RNase catalytic and antiviral functions.
Output: finding
Abundant nidovirus-like sequences were identified in cases and were used to assemble the genome of a previously unknown virus in the order Nidovirales.
Output: method
which correlated positively with the age of animals at the time of infection.
Output: finding
We performed a 15-year follow-up on the lung and bone conditions of SARS patients.
Output: method
age groups below 6 months were found to be more prone to parvovirus infection and males were mostly infected.
Output: finding
Currently there 32 is no targeted therapeutics and effective treatment options remain very limited.
Output: background
and it was 137.4 and 53.3 times faster than the CFD-Lagrangian model in predicting the steady-state airflow and transient particle transport.
Output: finding
Today the plague is still endemic in many countries of the world.
Output: finding
Here we describe Y2H screening strategies that use defined libraries of open reading frames ( ORFs ) and cDNA libraries.
Output: purpose
CLSM-FRET analysis determined the interaction of cav-1α and cav-2 in situ.
Output: method
intensive care units continue to see frequent patients with HIV infection.
Output: background
Demographics were similar between the 2 groups.
Output: finding
as a model for severe acute respiratory syndrome ( SARS ).
Output: purpose
The growth advantage observed before weaning in the ACD calves likely disappeared due to the weaning methods used.
Output: finding
It has occurred in three huge pandemics since the 6 th century with millions of deaths and numerous smaller epidemics and sporadic cases.
Output: background
and HA isolation gown for routine patient care and performing aerosol-generating procedures ( PPE3 ) to prevent EVD transmission by measuring the degree of contamination of HCWs and the environment.
Output: purpose
Resveratrol is a naturally occurring phytoalexin in specific plants and exhibits inhibitory activity against many kinds of virus.
Output: background
we will discuss some recent progress regarding the possible clinically relevant use of the N-protein.
Output: method
The goal of this chapter is to provide a comprehensive overview of olfactory disturbances as it pertains to the sinonasal airway.
Output: purpose
secondary structure elements , and the amino acid types.
Output: method
Study design-This was an observational cohort study in two primary care pediatric practices in Madison , WI.
Output: method
is closely associated with diarrhoea in human and causes infection of 165 million people worldwide per year.
Output: background
all four mutants replicated as efficiently as wild-type virus.
Output: finding
hepatitis B , foot-and-mouth disease , and Norwalk virus.
Output: background
A contact investigation was initiated to identify possible person-to-person transmission and assess infection control measures.
Output: method
Virus shedding was monitored using reverse-transcription quantitative polymerase chain reaction ( RT-qPCR ) controlled for faecal inhibitors to ensure sensitivity.
Output: method
Esto confirma que los anticuerpos IgG1 calostrales son críticos para la prevención de la infección por este agente viral.
Output: finding
and age-associated prevalence among camels at the largest entry port of camels from Africa into the Arabian Peninsula.
Output: purpose
which emerged in China in early 2013.
Output: purpose
To extend these findings , here we tested the efficacy of SCT DNA vaccines against bacterial infections.
Output: method
We show that the NTD is a novel RNA-binding domain with poly ( rA ) - preference cooperating with the TOPRIM domain in binding of RNA.
Output: finding
In this review , we summarize the current views on how aging influences the factors that impact T cell function and how this can affect the immune response to infections , vaccinations , and tumors.
Output: purpose
We therefore intended to present data obtained from a short-term overcrowded neonatal intermediate care unit ( NIMCU ) at a level III ( international categorization ) perinatal center at University Hospital Frankfurt , Germany.
Output: purpose
has been mapped to mutations in the viral thymidine kinase and the DNA polymerase catalytic subunit , respectively ( 7 ).
Output: background
Methods : We conducted a content analysis of all television news items about pH1N1.
Output: method
This approach is limited to targeting one amyloidogenic protein at a time.
Output: background
virus-cell interaction , and viral morphogenesis.
Output: purpose
These differences were also observed when the total protein levels in both groups were compared ( p = 0.0081 ).
Output: finding
We comprehensively reviewed the epidemiology of childhood diarrhoea and pneumonia in 2010-11 to inform the planning of integrated control programmes for both illnesses.
Output: purpose
The present study aims to analyze the miRNAs related to pathogenicity of nephropathogenic IBVs.
Output: purpose
Samples were deemed to be positive if they tested positive for a virus by at least two of the three respective assays.
Output: method
but test results for respiratory and serum samples were negative for MERS-CoV.
Output: finding
as nanoagents for drug delivery.
Output: background
citizen 's groups and military units based on independence and autonomy ( 1 ) ( 2 ) ( 3 ) ( 4 ) ( 5 ) ( 6 ) ( 7 ) ( 8 ) ( 9 ) ( 10 ) ( 11 ).
Output: background
which have been reported to be involved in viral replication.
Output: background
we have introduced in our clinical setting the quantitative detection of Epstein-Barr virus ( EBV ) in T-cell-depleted allogeneic stem cell transplant patients.
Output: purpose
as determined via PCR or ELISA , were enrolled.
Output: method
Coxsackieviruses are enteric viruses that frequently infect humans.
Output: background
and their abundance correlated with viral load ( Ct value ) , confirming HRSV infection.
Output: method
depending on serotypes , thus the Fab could have a smaller antiviral activity than the mAb in vitro.
Output: finding
as a treatment for calf diarrhea.
Output: background
taking into account the specific route and activities of the travel group.
Output: method
and production of clumping factor ( determined with the Staphyslide test ; bioMérieux ).
Output: finding
We established a cold-adapted infectious bronchitis virus ( BP-caKII ) by passaging a field virus through specific pathogen-free embryonated eggs 20 times at 32 • C.
Output: method
since failure to clear even one cat can result in re-infection of the others.
Output: finding
G-quadruplexes are present in eukaryotes , prokaryotes , and viruses.
Output: background
and the sensitivities of IgM and IgG rose to 52.2 % and 91.3 % , respectively.
Output: finding
This is a technique used routinely in our virology laboratory to detect BCoV from stool and nasopharyngeal samples of cattle.
Output: purpose
both with and without dietary exposure to the PPARA agonist WY-14643.
Output: finding
while public communication tends to favor more categorical claims.
Output: background
At each level , information is solicited to assess five key risks that are most relevant to each level of operations.
Output: background
thymus and CD34 + stem cells or ( 3 ) primary human skeletal muscle cells.
Output: method
Results : IFN-γ +874 A allele was associated with susceptibility to SARS in a dose-dependent manner ( P < 0.001 ).
Output: finding
Dengue severity was determined according to the 2009 WHO classification guidelines.
Output: method
A variety of perturbants were employed to characterize the cellular processes involved.
Output: method
Nonetheless , data interpretation and real understanding of viral dynamics is still hampered by the sheer complexity of the various intertwined spatio-temporal processes.
Output: background
In this connection G-quadruplex recognition and processing by nucleic acid directed proteins and enzymes represents a key event to activate or deactivate physiological or pathological pathways.
Output: background
the raccoon dog should receive more attention in disease prevention and eradication strategies.
Output: finding
we applied a modified traveling salesman algorithm.
Output: method
This observation suggests that a number of the newly identified sRNAs in strain 2336 may be involved in strain-specific adaptations.
Output: finding
as well as for surveillance of foodborne and waterborne viruses ( 20 ) ( 21 ) ( 22 ) ( 23 ) ( 24 ) ( 25 ) ( 26 ).
Output: background
A series of experiments in vitro suggested that chronic demyelination is due to a bystander mechanism associated with the virus-induced immune response in which antibody dependent cell-mediated reactions play an important role.
Output: finding
volatiles , and antioxidants potential in medicinal plants.
Output: purpose
89.6 % could taste the commercial solution and 91.7 % could taste the homemade solution.
Output: finding
axonal damage and neurologic disability.
Output: background
This review provides a comparison of the theoretical issues and experimental findings for plasmid DNA and mRNA vaccine technologies.
Output: purpose
as an additional member of the new family Mesoniviridae in the order Nidovirales.
Output: method
Background : Some island nations have explicit components of their influenza pandemic plans for providing travel warnings and restricting incoming travellers.
Output: background
Pairs grouped into the category of emerging and reemerging diseases were employed to investigate conformity bias ; pairs belonging to the category esthetic uses were considered to be of little adaptive relevance and utilized as an experimental control.
Output: method
but was found in lymphatic tissue through day 42 after challenge.
Output: finding
Gm15441-null mice were developed and shown to be more susceptible to NLRP3 inflammasome activation and to exhibit elevated CASP1 and IL1B cleavage in response to metabolic and inflammatory stimuli.
Output: background
Methods.
Output: method
We recommend that this study be conducted on a larger scale to support our findings.
Output: finding
Two clusters of patients were defined from chronological data and phylogenetic trees.
Output: finding
In contrast , Japan suffered the shortest bubble period and no evidence has documented the existence of crash there.
Output: finding
Sprague-Dawley rats were injected intraperitoneally with a suspension of Trypanosoma brucei brucei.
Output: background
e.g. in the development of vaccines for new viruses.
Output: background
and 70 % outside the household ( see Supplementary Information ).
Output: method
a Chinese herbal formula , in the treatment of patients with wind-cold type common cold.
Output: purpose
The expression of 68Kp '' '' was restricted to mammary tissues of BALB/cV mice that also expressed other MMTV proteins.
Output: finding
The combined data were used to characterize the relationship of the translated proteins of 2019-nCoV to other species of Orthocoronavirinae.
Output: method
but detection of viral RNA does not necessarily indicate a transmission potential.
Output: finding
The binding constants were estimated by the change of migration time of the analytes in the buffer solution containing different concentrations of SARS 3CL proteinase.
Output: method
namely framework genes , including three olfactory receptor genes.
Output: finding
DNA samples from 410 febrile children and 60 afebrile children were analyzed by quantitative PCR.
Output: method
underwent clinical evaluation , fractional exhaled nitric oxide measurement , and sputum induction.
Output: method
Clara cell secretory protein ( CCSP ) is specifically expressed in pulmonary Clara cells and is widely used as a Clara cell marker.
Output: background
Consistent with these data , we showed that Tat transactivation of the Egr-1 promoter was abrogated when astrocytes were cultured in serum-reduced media.
Output: finding
Therefore , we investigated which cells are stimulated to produce IFN-I following CVB3 infection and which cell types have to be IFNAR-triggered in order to confer antiviral protection.
Output: purpose
In this report , ribavirin was shown to inhibit SARS-CoV replication in five different cell types of animal or human origin at therapeutically achievable concentrations.
Output: purpose
Background Acute respiratory tract infections ( ARTIs ) are one of the major causes of morbidity and mortality among young children in developing countries.
Output: background
with which the present technological and managing situations are not completely compliant.
Output: background
Starting in the 1960s , the human adenovirus type 12 ( Ad12 ) system has been used in my laboratory to investigate basic mechanisms in molecular biology and viral oncology.
Output: background
have been traditionally consumed in various forms by Philippinos for treatment of diabetes and kidney related diseases.
Output: background
Exaggerated complement activation is a key event in the pathogenesis of a range of autoimmune and inflammatory diseases.
Output: background
The overall objective of this study was to compare the efficacy of medium-chain fatty acids ( MCFA ) to other common fat sources to minimize the risk of porcine epidemic diarrhea virus ( PEDV ) cross-contamination in a pig bioassay.
Output: purpose
Our results suggest that theaflavin could be the candidate of SARS-CoV-2 entry inhibitor for further study.
Output: finding
We previously identified unusual variants of Moloney and Friend ecotropic mouse gammaretroviruses that have altered host range and are cytopathic in cells of the wild mouse species Mus dunni.
Output: background
These model predictions have shown a wide range of variations.
Output: background
and to both CFT and ELISA with immune animals ( r > 0.96 ).
Output: finding
visited two hospitals in Mecca.
Output: finding
Histone acetylation changes were validated by biochemistry assays.
Output: method
economy-class cabin of Boeing 767 and 737 airplanes.
Output: method
including opportunities to apply new science and technology.
Output: finding
and slightly higher than the SNP rate observed in human MHC ( 0.00337 SNP per bp ).
Output: finding
Follow-up visits were conducted for 2 years after the episode of bronchiolitis.
Output: method
This study is aimed to understand the seasonal distribution and clinical manifestations of HCoV-NL63 infection in children in Taiwan.
Output: purpose
and - DRB loci on the 6 common haplotypes.
Output: purpose
in lung tissues of smokers without airflow limitation and COPD patients in comparison to nonsmoking individuals ( never-smokers ).
Output: purpose
with substantial associated costs and morbidity.
Output: background
Exposure to MERS-CoV during a hospital visit is considered a likely source of infection for Case 1 but not for Case 2.
Output: finding
Posttraumatic stress disorder ( PTSD ) can arise in patients with medical illness.
Output: background
We assessed risk of bias for each individual study and used GRADE to ascertain the certainty of the evidence.
Output: method
However , little is known about the disease burden and the molecular epidemiology of HAdV.
Output: background
Photoactivated Orthoquin inhibited herpes simplex virus type 1 ( HSV-1 ) and herpes simplex virus type 2 ( HSV-2 ) infection of target cells in a dose-dependent manner across a broad range of sub-cytotoxic concentrations.
Output: finding
We apply this framework on two major pathogens that infect African 48 lions : canine distemper virus ( CDV ) and feline parvovirus.
Output: method
quick , and safe cell adhesion inhibition assay was developed to determine the potential cellular binding site on the SARS-CoV spike protein.
Output: purpose
pegIFN-α can be administrated , but is only suited for the subset of liver-transplant recipients ( 12 ) ( 13 ) ( 14 ) ( 15 ).
Output: method
Purpose of the review-We describe the history of passive immunization to provide context for the series of articles to follow.
Output: purpose
In addition , HAdV burden and co-infection was evaluated for samples tested in laboratory analysis packages.
Output: method
Furthermore , the contributions of monocyte-derived subsets to viral clearance and immunopathology are not well-defined.
Output: background
including compound structure-function studies , insect cell functionality augmentation , and VLP production.
Output: purpose
But until now , SCUB analysis has been performed only in chloroplast genome of G. hirsutum ( 36 ).
Output: background
human Bocavirus in patients above a year of age was more common ( p < 0.05 ).
Output: finding
We used electron microscopy to identify murine coronaviruses with mutations in nsp3 and nsp14 that replicated normally while producing only half the normal amount of DMVs under low-temperature growth conditions.
Output: method
The purpose of this study is to investigate the ongoing development of China 's PHERIS.
Output: purpose
Utilizing the YSD technique , antigens specific to the target antibody are displayed on the surface of engineered yeast cells with intracellular fluorescent proteins.
Output: background
acute myocardial injury ( AMI ) in COVID-19 patients has not been previously investigated in detail.
Output: background
We have also discovered that the insertion of foreign ( Ad12 , bacteriophage lambda , plasmid ) DNA into mammalian genomes can lead to genome-wide alterations in methylation and transcription patterns in the recipient genomes.
Output: background
These models allow us to derive threshold conditions that can be used to assess the effectiveness of vaccine and drug use and to determine disease outcomes.
Output: background
Attachment is followed by a redistribution or capping of virus particles on the cell surface which may play a role in the uptake process.
Output: background
exhibited neurotropism , and were mildly neurovirulent in neonatal ddY mice.
Output: finding
We describe disease-pathogen associations of respiratory viruses and quantify virus-specific attributable risk of ARIs in healthy children during the first 2 years of life.
Output: purpose
paper and hydrogels are alternatives due to their distinct structural and mechanical properties for a number of applications.
Output: background
We have conducted a systematic review to synthesise evidence about the uptake and effectiveness of facemask against respiratory infections in MGs.
Output: purpose
to the financial crisis and global recession of 2008 and subsequent ` austerity agenda ' of state retrenchment.
Output: purpose
In addition , it explores potential means to continue to educate trainees during the COVID-19 pandemic.
Output: purpose
Diseases 2016 , 4 , 26 2 of 27 SARS-CoV but with a much higher mortality rate of about 35 % ( 17 ).
Output: finding
However , the reversible reaction used for DCL formation should equilibrate fast enough to allow re-equilibration by the target on a timescale during which the target remains stable.
Output: background
which is the primary purpose of the paper.
Output: purpose
Moreover , we show that the addition of MPA to S. cerevisiae cells leads to a reduction of capped mRNAs.
Output: finding
In the white matter , the reaction was moderate.
Output: finding
laboratory test results , response to treatment , and relapses.
Output: method
This study aims to determine the levels of the IL-1 family ( IL-1β , 54 IL-37 ) and IL-12 family ( IL-12 , IL-35 ) in a group of these patients and the association 55 between these cytokines levels and the patients ' demographic characteristics.
Output: purpose
Herein , we report the glycosylation mapping on spike protein subunits S1 and S2 expressed on human cells through high resolution mass spectrometry.
Output: background
These constitute the modern immunological basis for the development of novel clinical and preclinical immunomodulatory therapies for MS discussed in this paper.
Output: purpose
The sensitivity of EM increased 25 % after virus concentration by ultracentrifugation.
Output: method
Incorporating these approaches in economic analyses of AECB antimicrobial therapy can help health care organizations make evidence-based decisions regarding the cost-effective management of AECB.
Output: finding
but to the inhibition of viral multiplication in host cells.
Output: finding
describes MERS vaccine criteria , and presents available small animal models to evaluate the efficacy of MERS vaccines.
Output: purpose
We consider a ` SIR ' type model for the 60 host population and a ` SI ' type model for the vectors.
Output: method
followed by a template with details on the safety and characteristics of a rVSV vaccine against Zaire ebolavirus ( ZEBOV ).
Output: purpose
but also in financial time series.
Output: finding
It has been proposed that all diploid cotton species may have evolved from a common ancestor and allopolyploid cotton may have appeared through hybridization and subsequent polyploidization events between the A-and D-subgenome progenitors.
Output: background
In 1994 the Republic was linked directly by air with more overseas than African countries and cities ; within a decade the pattern reversed.
Output: background
Homotypic interaction involving Domain III of MHV nsp15 was further demonstrated biochemically.
Output: finding
Mx1 , IFN-β , and OAS-1 as compared with control MDBK cells.
Output: finding
The most common symptom was fever.
Output: finding
Unlike natural populations , the structure of this panel allows the serial evaluation of genetically identical individuals and the quantification of genotype-specific effects of interventions such as vaccination.
Output: method
which encompasses both communicable and non-communicable diseases.
Output: purpose
wind speed classification is derived based on Physiological Equivalent Temperature ( PET ) to evaluate the effect of wind speed on outdoor thermal comfort.
Output: method
The objective of this study was to investigate the inactivation performance of dialdehyde starch ( DAS ) treated filters against airborne viruses.
Output: purpose
Local stability of endemic equilibria is studied.
Output: method
We review the techniques and guidelines that our institution has implemented in order to allow us to do just that.
Output: purpose
including avian , swine and humans.
Output: background
Additionally , a positive plasmid control was established as an internal control.
Output: method