One hundred methanolic plant extracts were screened for antiviral activity against seven viruses. Twelve extracts were found to have antiviral activity at the noncytotoxic concentrations tested. The extracts of Rosa nutkunu and Amelunchier alnifoliu, both members of the Rosaceae, were very active against an enteric coronavirus. A root extract of another member of the Rosaceae, Potentillu urgutu, completely inhibited respiratory syncytial virus. A Sumbucus rucemosu branch tip extract was also very active against respiratory syncytial virus while the inner bark extract of Oplopunux horridus partially inhibited this virus. An extract of Ipomopsis uggregutu demonstrated very good activity against parainfluenza virus type 3. A Lomatium dissectum root extract completely inhibited the cytopathic effects of rotavirus. In addition to these, extracts prepared from the following plants exhibited antiviral activity against herpesvirus type 1: Carriamine angulatu, Conocephalum conicum, Lysichiton umericunum, Polypodium glycyrrhizu and Verbuscum thapsus. Achilles millefolium L. var. occidentalis DC. (Compositae) P-IO Whole plant Alnus rubra Bong. (Betulaceae) Q-l Bark, Q-2 Catkins Ambrosia chamissonis (Less.) Greene var. chamissonis (Compositae) Q-29 Aerial parts Amelanchier alnifolia Nutt. var. humptulipensis (Jones) Hitchc. (Rosaceae) P-6, P-15 Branches Antennaria microphylla Rydb. (Compositae) P-21 Whole plant Arctostaphylos uva-ursi (L.) Spreng. (Ericaceae) P-42a Branches, P-42b roots Argentina egedii (Womwk.) Rydb. (Rosaceae) Q-20 Aerial parts Arnica cordI$olia Hook. (Compositae) P-31 Aerial parts Arnica sororia Greene (Compositae) P-7 Aerial parts Artemisia ludoviciana Nutt. ssp. ludoviciana (Compositae) W-5 Aerial parts Artemisia michauxiana Bess. (Compositae) P-29 Aerial parts Artemisia tridentata Nutt. ssp. tridentata (Compositae) W-19 Branches Aruncus dioicus (Walt.) Fem. var. vuIgaris (maxim) Hara (Rosaceae) F-l Branches Asarum caudatum Lindl. (Aristolochiaceae) W-12 Whole plant Balsamorhiza sagittata (Pursh) Nutt. (Compositae) W-18 Aerial parts, P-2 roots Betula papy@ra Marsh (Betulaceae) P-38 Branches Capsella bursa-pastoris Medic. (Cruciferae) W-8 Whole plant Car&mine angulata Hook. (Cruciferae) Q-16 Roots Ceanothus velutinus Do@. ex Hook. (Rhamnaceae) P-39 Branches Chaenactis aiwglasii (Hook.) H. et A. (Compositae) P-3 Whole plant Chrysothamnw nauseosus (Pall.) Britt. ssp. albicaulis (Nutt.) H. et C. (Compositae) P-25 Branches Clematis ligusticifolia Nutt. ex T. et G. (Ranunculaceae) P-14 Aerial parts Conocephalwn conicum Plantago major L. (Plantaginaceae) Q-22 Whole Plant Polypodium glycyrrhiza D.C. Eaton (Polypodiaceae) Rhizomes Q-27 Polystichum munitum (Kaulf.) Presl (Polypodiaceae) Rhizomes Q-15 Popular tremuloides Michx. (Salicaceae) P-34 Branches Potentilla arguta Pursh (Rosaceae) W-7 Roots Prune virginiana L. var. demissa (Nutt.) Torr. (Rosaceae) W-9 Branches Prunes virginiana L. var. melanocarpa (Nels.) Sarg. (Rosaceae) P-40 Branches Thus glabra L. (Anacardiaceae) P-23 Branches Ribes sanguineum Pursh (Grossulariaceae) P-18 Branches Rosa nutkana Presl var. nutkana (Rosaceae) P-5 Branches Rubus parviflorus Nutt. (Rosaceae) P-28 Branches Salix bebbiana Sarg. (Salicaceae) P-36 Branches Sambucus cerulea Raf. (Caprifoliaceae) P-16 Branches Sambucus racemosa L. ssp. pubens (Michx.) House var. arborescens (T. et G.) A. Gray (Caprifoliaceae) Q-2 I Branches Sedum lanceolatum Torr. (Crassulaceae) P-20 Whole plant Shepherdia canadensis (L.) Nutt. (Elaeagnaceae) W-16 Berries Spiraea betultjolia Pall. (Rosaceae) P-41 Branches Symphoricarpos albus (L.) Blake var. laevigatus Fern. (Caprifoliaceae) P-26 Branches Urtica dioica L. ssp. gracilis (Ait.) Seland. var. lyallii (Wats.) Hitchc. (Urticaceae) P-27 Aerial parts Verbascum thapsus L. (Scrophulariaceae) P-24 Leaves Collectors for all species were A.R. McCutcheon and S.M. Ellis.
Output: Antiviral screening of British Columbian medicinal plants