nils-herrmann/clean_scirepeval huggingface dataset:
Fully printed flexible fingerprint-like three-axis tactile and slip force and temperature sensors for artificial skin.

A three-axis tactile force sensor that determines the touch and slip/friction force may advance artificial skin and robotic applications by fully imitating human skin. The ability to detect slip/friction and tactile forces simultaneously allows unknown objects to be held in robotic applications. However, the functionalities of flexible devices have been limited to a tactile force in one direction due to difficulties fabricating devices on flexible substrates. Here we demonstrate a fully printed fingerprint-like three-axis tactile force and temperature sensor for artificial skin applications. To achieve economic macroscale devices, these sensors are fabricated and integrated using only printing methods. Strain engineering enables the strain distribution to be detected upon applying a slip/friction force. By reading the strain difference at four integrated force sensors for a pixel, both the tactile and slip/friction forces can be analyzed simultaneously. As a proof of concept, the high sensitivity and selectivity for both force and temperature are demonstrated using a 3×3 array artificial skin that senses tactile, slip/friction, and temperature. Multifunctional sensing components for a flexible device are important advances for both practical applications and basic research in flexible electronics.
Multidimensional assessment of emotion regulation difficulties in adolescents using the Difficulties in Emotion Regulation Scale.

The authors explored the utility of the Difficulties in Emotion Regulation Scale (DERS) in assessing adolescents' emotion regulation. Adolescents (11-17 years; N = 870) completed the DERS and measures of externalizing and internalizing problems. Confirmatory factor analysis suggested a similar factor structure in the adolescent sample of the authors as demonstrated previously among adults. Furthermore, results indicated no gender bias in ratings of DERS factors on three scales (as evidenced by strong factorial gender invariance) and limited gender bias on the other three scales (as evidenced by metric invariance). Female adolescents scored higher on four of six DERS factors than male adolescents. DERS factors were meaningfully related to adolescents' externalizing and internalizing problems. Results suggest that scores on the DERS show promising internal consistency and validity in a community sample of adolescents.
A comparison of the transverse, axial and radial flux PM synchronous motors for electric vehicle

This paper presents the performance comparison among three different topologies of the permanent magnet synchronous machine, namely a transverse flux permanent magnet machine with flux concentration and claw pole structure, an axial flux machine with segmented armature torus structure and a conventional radial flux machine with embedded permanent magnets in the rotor. With the help of Finite Element Method, three electrical machines have been designed considering the required dimensions and permanent magnets mass. The complete results evaluation and comparisons are described in this paper. From the obtained results it can be concluded, the axial flux machine with segmented armature torus structure can be a competitive alternative compared with the conventional radial flux machine for applications with limited axial length, while the transverse flux machine is an attractive alternative for the high torque and low-speed applications due to its high pole number.
MicroRNA-221 Induces Cell Survival and Cisplatin Resistance through PI3K/Akt Pathway in Human Osteosarcoma

MicroRNAs are short regulatory RNAs that negatively modulate protein expression at a post-transcriptional and/or translational level and are deeply involved in the pathogenesis of several types of cancers. Specifically, microRNA-221 (miR-221) is overexpressed in many human cancers, wherein accumulating evidence indicates that it functions as an oncogene. However, the function of miR-221 in human osteosarcoma has not been totally elucidated. In the present study, the effects of miR-221 on osteosarcoma and the possible mechanism by which miR-221 affected the survival, apoptosis, and cisplatin resistance of osteosarcoma were investigated.



Real-time quantitative PCR analysis revealed miR-221 was significantly upregulated in osteosarcoma cell lines than in osteoblasts. Both human osteosarcoma cell lines SOSP-9607 and MG63 were transfected with miR-221 mimic or inhibitor to regulate miR-221 expression. The effects of miR-221 were then assessed by cell viability, cell cycle analysis, apoptosis assay, and cisplatin resistance assay. In both cells, upregulation of miR-221 induced cell survival and cisplatin resistance and reduced cell apoptosis. In addition, knockdown of miR-221 inhibited cell growth and cisplatin resistance and induced cell apoptosis. Potential target genes of miR-221 were predicted using bioinformatics. Moreover, luciferase reporter assay and western blot confirmed that PTEN was a direct target of miR-221. Furthermore, introduction of PTEN cDNA lacking 3'-UTR or PI3K inhibitor LY294002 abrogated miR-221-induced cisplatin resistance. Finally, both miR-221 and PTEN expression levels in osteosarcoma samples were examined by using real-time quantitative PCR and immunohistochemistry. High miR-221 expression level and inverse correlation between miR-221 and PTEN levels were revealed in osteosarcoma tissues.



These results for the first time demonstrate that upregulation of miR-221 induces the malignant phenotype of human osteosarcoma whereas knockdown of miR-221 reverses this phenotype, suggesting that miR-221 could be a potential target for osteosarcoma treatment.
Torque Estimation for Robotic Joint With Harmonic Drive Transmission Based on Position Measurements

Joint torque sensory feedback is an effective technique for achieving high-performance robot force and motion control. However, most robots are not equipped with joint torque sensors, and it is difficult to add them without changing the joint's mechanical structure. A method for estimating joint torque that exploits the existing structural elasticity of robotic joints with harmonic drive transmission is proposed in this paper. In the presented joint torque estimation method, motor-side and link-side position measurements along with a proposed harmonic drive compliance model, are used to realize stiff and sensitive joint torque estimation, without the need for adding an additional elastic body and using strain gauges to measure the joint torque. The proposed method has been experimentally studied and its performance is compared with measurements of a commercial torque sensor. The results have attested the effectiveness of the proposed torque estimation method.
Bondability Study of Chip-on-Film (COF) Inner Lead Bonding (ILB) Using Conventional Gang Bonder

Inner lead bonding (ILB) is used to thermomechanically join the Cu inner leads on a flexible film tape and Au bumps on a driver IC chip to form electrical paths. With the newly developed film carrier assembly technology, called chip on film (COF), the bumps are prepared separately on a film tape substrate and bonded on the finger lead ends beforehand; therefore, the assembly of IC chips can be made much simpler and cheaper. In this paper, three kinds of COF samples, namely forming, wrinkle, and flat samples, were prepared using conventional gang bonder. The peeling test was used to examine the bondability of ILB in terms of the adhesion strength between the inner leads and the bumps. According to the peeling test results, flat samples have competent strength, less variation, and better appearance than when using flip-chip bonder.
NIHRIO at SemEval-2018 Task 3: A Simple and Accurate Neural Network Model for Irony Detection in Twitter

This paper describes our NIHRIO system for SemEval-2018 Task 3 “Irony detection in English tweets.” We propose to use a simple neural network architecture of Multilayer Perceptron with various types of input features including: lexical, syntactic, semantic and polarity features. Our system achieves very high performance in both subtasks of binary and multi-class irony detection in tweets. In particular, we rank third using the accuracy metric and fifth using the F1 metric. Our code is available at: https://github.com/ NIHRIO/IronyDetectionInTwitter.
A Review of Computer Vision System for the Vehicle Identification and Classification from Online and Offline Videos

The traffic on the roads is increasing day by day. There is dire need of developing an automation system that can effectively manage and control the traffic on roads. The traffic data of multiple vehicle types on roads is also important for taking various decisions related to traffic. A video based traffic data collection system for multiple vehicle types is helpful for monitoring vehicles under homogenous and heterogeneous traffic conditions. In this paper, we have studied different methods for the identification, classification and counting vehicles from online and offline videos in India as well as other countries. The paper also discusses the various applications of video based automatic traffic control system. The various challenges faced by the researchers for developing such systems are also discussed.
Successful treatment of Candida albicans septicemia in a preterm infant with severe congenital ichthyosis (Harlequin baby).

Candida infections are a major cause of fungal septicemia in neonates and are associated with marked morbidity and mortality. Despite the spectrum of antifungal drugs being dramatically extended during the last decade, invasive fungal infections remain a serious challenge for neonatologists. Amphotericin B and its lipid formulations are the drugs of choice for the treatment of systemic candidiasis in neonates. The combination of antifungal drugs with different sites of action, like caspofungin and amphotericin B, may improve antifungal efficacy. Severe congenital ichthyosis often leads to death within the neonatal period. Main causes of death are dehydration, electrolyte disturbances, and respiratory or systemic infections. We report the case of a preterm infant with severe congenital ichthyosis and sepsis caused by Candida albicans. The infection did not improve despite proper liposomal amphotericin B treatment. After addition of caspofungin, the baby recovered. To our best knowledge, a case of a preterm infant suffering from severe congenital ichthyosis and Candida albicans sepsis, who survived, has not been previously described.
The Sforzesco brace and SPoRT concept: a brace to replace cast in worst curves.

Bracing still remains the most important conservative treatment for scoliosis; approaches to bracing are really many and diverse. The aim of this paper of this paper, is the presentation of the brace we recently developed (the Sforzesco brace and SPoRT concept) to face worst scoliosis, in the past treated through casting.



The SPoRT concept was born while we were looking for a new brace; it means Symmetric, Patient oriented, Rigid, Three-dimensional and Active. Details of construction and the biomechanical principle of its corrective action are reported. This brace has been used widely in the last 3 years.



The Sforzesco brace showed to be more effective than the Lyon brace and as effective as the Risser cast on different clinical and radiological outcome measures in 2 different prospective study of best clinical practice.



When compared to the other braces, the Sforzesco can find its place in the most important curves, in which there are no alternatives to try avoiding surgery. The SPoRT Concept appear a useful tool to interpret what happens with this brace, even if in the future could be overcome by new theories according to new (and awaited) results in the literature.
Non-fatal impalement of the brain: A case report.

We present a rare case of a non-fatal impalement injury of the brain. A 13-year-old boy was found in his classroom unconsciously lying on floor. His classmates reported that they had been playing, and throwing building bricks, when suddenly the boy collapsed. The emergency physician did not find significant injuries. Upon admission to a hospital, CT imaging revealed a "blood path" through the brain. After clinical forensic examination, an impalement injury was diagnosed, with the entry wound just below the left eyebrow. Eventually, the police presented a variety of pointers that were suspected to have caused the injury. Forensic trace analysis revealed human blood on one of the pointers, and subsequent STR analysis linked the blood to the injured boy. Confronted with the results of the forensic examination, the classmates admitted that they had been playing "sword fights" using the pointers, and that the boy had been hit during the game. The case illustrates the difficulties of diagnosing impalement injuries, and identifying the exact cause of the injury.
Nocturnal road traffic noise: A review on its assessment and consequences on sleep and health.

Research on the impact of nocturnal road traffic noise on sleep and the consequences on daytime functioning demonstrates detrimental effects that cannot be ignored. The physiological reactions due to continuing noise processing during night time lead to primary sleep disturbances, which in turn impair daytime functioning. This review focuses on noise processing in general and in relation to sleep, as well as methodological aspects in the study of noise and sleep. More specifically, the choice of a research setting and noise assessment procedure is discussed and the concept of sleep quality is elaborated. In assessing sleep disturbances, we differentiate between objectively measured and subjectively reported complaints, which demonstrates the need for further understanding of the impact of noise on several sleep variables. Hereby, mediating factors such as noise sensitivity appear to play an important role. Research on long term effects of noise intrusion on sleep up till now has mainly focused on cardiovascular outcomes. The domain might benefit from additional longitudinal studies on deleterious effects of noise on mental health and general well-being.
Augmented Piano Performance using a Depth Camera

We augment the piano keyboard with a 3D gesture space using Microsoft Kinect for sensing and top-down projection for visual feedback. This interface provides multi-axial gesture controls to enable continuous adjustments to multiple acoustic parameters such as those on the typical digital synthesizers. We believe that using gesture control is more visceral and aesthetically pleasing, especially during concert performance where the visibility of the performer’s action is important. Our system can also be used for other types of gesture interaction as well as for pedagogical applications.
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.

"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure" provides a new guideline for hypertension prevention and management. The following are the key messages(1) In persons older than 50 years, systolic blood pressure (BP) of more than 140 mm Hg is a much more important cardiovascular disease (CVD) risk factor than diastolic BP; (2) The risk of CVD, beginning at 115/75 mm Hg, doubles with each increment of 20/10 mm Hg; individuals who are normotensive at 55 years of age have a 90% lifetime risk for developing hypertension; (3) Individuals with a systolic BP of 120 to 139 mm Hg or a diastolic BP of 80 to 89 mm Hg should be considered as prehypertensive and require health-promoting lifestyle modifications to prevent CVD; (4) Thiazide-type diuretics should be used in drug treatment for most patients with uncomplicated hypertension, either alone or combined with drugs from other classes. Certain high-risk conditions are compelling indications for the initial use of other antihypertensive drug classes (angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, beta-blockers, calcium channel blockers); (5) Most patients with hypertension will require 2 or more antihypertensive medications to achieve goal BP (<140/90 mm Hg, or <130/80 mm Hg for patients with diabetes or chronic kidney disease); (6) If BP is more than 20/10 mm Hg above goal BP, consideration should be given to initiating therapy with 2 agents, 1 of which usually should be a thiazide-type diuretic; and (7) The most effective therapy prescribed by the most careful clinician will control hypertension only if patients are motivated. Motivation improves when patients have positive experiences with and trust in the clinician. Empathy builds trust and is a potent motivator. Finally, in presenting these guidelines, the committee recognizes that the responsible physician's judgment remains paramount.
Assessing the Effectiveness of Neurofeedback Training in the Context of Clinical and Social Neuroscience

Social neuroscience benefits from the experimental manipulation of neuronal activity. One possible manipulation, neurofeedback, is an operant conditioning-based technique in which individuals sense, interact with, and manage their own physiological and mental states. Neurofeedback has been applied to a wide variety of psychiatric illnesses, as well as to treat sub-clinical symptoms, and even to enhance performance in healthy populations. Despite growing interest, there persists a level of distrust and/or bias in the medical and research communities in the USA toward neurofeedback and other functional interventions. As a result, neurofeedback has been largely ignored, or disregarded within social neuroscience. We propose a systematic, empirically-based approach for assessing the effectiveness, and utility of neurofeedback. To that end, we use the term perturbative physiologic plasticity to suggest that biological systems function as an integrated whole that can be perturbed and guided, either directly or indirectly, into different physiological states. When the intention is to normalize the system, e.g., via neurofeedback, we describe it as self-directed neuroplasticity, whose outcome is persistent functional, structural, and behavioral changes. We argue that changes in physiological, neuropsychological, behavioral, interpersonal, and societal functioning following neurofeedback can serve as objective indices and as the metrics necessary for assessing levels of efficacy. In this chapter, we examine the effects of neurofeedback on functional connectivity in a few clinical disorders as case studies for this approach. We believe this broader perspective will open new avenues of investigation, especially within social neuroscience, to further elucidate the mechanisms and effectiveness of these types of interventions, and their relevance to basic research.
Memo 71 Focal-Plane Array Architectures : Horn Clusters vs . Phased-Array Techniques

The science goals of the SKA specify a field of view which is far greater than what current radio telescopes provide. Two possible feed architectures for reflector antennas are clusters of horns or phased-array feeds. This memo compares these two alternatives and finds that the beams produced by horn clusters fall short of fully sampling the sky and require interleaved pointings, whereas phased-array feeds can provide complete sampling with a single pointing. Thus for a given focal-plane area horn clusters incur an equivalent system temperature penalty of ∼ 2× or more. The situation is worse for wide-band feeds since the spacing of the beams is constant while the beamwidth is inversely proportional to frequency, increasing the number of pointings for a fully-sampled map at the high-end of an operating band. These disadvantages, along with adaptive beamforming capabilities, provide a strong argument for the development of phased-array technology for wide-field and wide-band feeds.
Ultra-Wideband Patch Antenna for K-Band Applications

An ultra-wideband patch antenna is presented for K-band communication. The antenna is designed by employing stacked geometry and aperture-coupled technique. The rectangular patch shape and coaxial fed configuration is used for particular design. The ultra-wideband characteristics are achieved by applying a specific surface resistance of 75Ω/square to the upper rectangular patch and it is excited through a rectangular slot made on the lower patch element (made of copper). The proposed patch antenna is able to operate in the frequency range of 12-27.3 GHz which is used in radar and satellite communication, commonly named as K-band. By employing a technique of thicker substrate and by applying a specific surface resistance to the upper patch element, an impedance bandwidth of 77.8% is achieved having VSWR ≤ 2. It is noted that the gain of proposed antenna is linearly increased in the frequency range of 12-26 GHz and after that the gain is decreased up to 6 dBi. Simulation results are presented to demonstrate the performance of proposed ultra-wideband microstrip patch antenna.
Vaginismus Treatment: Clinical Trials Follow Up 241 Patients

Vaginismus is mostly unknown among clinicians and women. Vaginismus causes women to have fear, anxiety, and pain with penetration attempts.



To present a large cohort of patients based on prior published studies approved by an institutional review board and the Food and Drug Administration using a comprehensive multimodal vaginismus treatment program to treat the physical and psychologic manifestations of women with vaginismus and to record successes, failures, and untoward effects of this treatment approach.



Assessment of vaginismus included a comprehensive pretreatment questionnaire, the Female Sexual Function Index (FSFI), and consultation. All patients signed a detailed informed consent. Treatment consisted of a multimodal approach including intravaginal injections of onabotulinumtoxinA (Botox) and bupivacaine, progressive dilation under conscious sedation, indwelling dilator, follow-up and support with office visits, phone calls, e-mails, dilation logs, and FSFI reports.



Logs noting dilation progression, pain and anxiety scores, time to achieve intercourse, setbacks, and untoward effects. Post-treatment FSFI scores were compared with preprocedure scores.



One hundred seventy-one patients (71%) reported having pain-free intercourse at a mean of 5.1 weeks (median = 2.5). Six patients (2.5%) were unable to achieve intercourse within a 1-year period after treatment and 64 patients (26.6%) were lost to follow-up. The change in the overall FSFI score measured at baseline, 3 months, 6 months, and 1 year was statistically significant at the 0.05 level. Three patients developed mild temporary stress incontinence, two patients developed a short period of temporary blurred vision, and one patient developed temporary excessive vaginal dryness. All adverse events resolved by approximately 4 months. One patient required retreatment followed by successful coitus.



A multimodal program that treated the physical and psychologic aspects of vaginismus enabled women to achieve pain-free intercourse as noted by patient communications and serial female sexual function studies. Further studies are indicated to better understand the individual components of this multimodal treatment program. Pacik PT, Geletta S. Vaginismus Treatment: Clinical Trials Follow Up 241 Patients. e114-e123.