nils-herrmann/clean_scirepeval huggingface dataset:
Broadband circularly polarized spiral antenna array

A circularly polarized (CP) spiral antenna array for wideband application is presented, which employs a simple single-arm spiral antenna(SASA), as the radiating element. By introducing a small round disc backed near the antenna center and loading a termination resistor, the SASA achieves wide impedance bandwidth without balun circuit and good axial ratio (AR) performance, respectively. A total of four array elements are used in the 2×2 configuration to obtain a higher gain. Particularly, a method of sequentially rotating the elements is used to improve the axial ratio. The array performs an impedance bandwidth for VSWR≤1.5 of 40% ranging from 1.25 to 1.88 GHz, an excellent AR of less than 0.74 dB, and a gain variation from 11.34 to 14.56 dB within the operating band. Measured and simulated results presented for the array confirm its wide impedance, axial ratio, and gain bandwidths. Acceptable agreement between the simulation and measured results validates the proposed design.
The UMass Mobile Manipulator UMan: An Experimental Platform for Autonomous Mobile Manipulation

Research in Autonomous Mobile Manipulation critically depends on the availability of adequate experimental platforms. In this paper, we describe an ongoing effort at the University of Massachusetts Amherst to construct a hardware platform with redundant kinematic degrees of freedom, a comprehensive sensor suite, and significant end-effector capabilities for manipulation. In our research, we pursue an end-effector centric view of autonomous mobile manipulation. In support of this view, we are developing a comprehensive software suite to provide a high level of competency in robot control and perception. This software suite is based on a multi-objective, tasklevel motion control framework. We use this control framework to integrate a variety of motion capabilities, including taskbased force or position control of the end-effector, collision-free global motion for the entire mobile manipulator, and mapping and navigation for the mobile base. We also discuss our efforts in developing perception capabilities targeted to problems in autonomous mobile manipulation. Preliminary experiments on our UMass Mobile Manipulator (UMan) are presented.
Using the domain analytical approach in the study of information practices in biomedicine

The purpose of this paper is to analyze the information practices of the researchers in biomedicine using the domain analytical approach.  The domain analytical research approach used in the study of the scientific domain of biomedicine leads to studies into the organization of sciences. By using Whitley’s dimensions of “mutual dependence” and “task uncertainty” in scientific work as a starting point the authors were able to reanalyze previously collected data. By opening up these concepts in the biomedical research work context, the authors analyzed the distinguishing features of the biomedical domain and the way these features affected researchers’ information practices.  Several indicators representing “task uncertainty” and “mutual dependence” in the scientific domain of biomedicine were identified. This study supports the view that in biomedicine the task uncertainty is low and researchers are mutually highly dependent on each other. Hard competition seems to be one feature, which is behind the explosion of the data and publications in this domain. This fact, on its part is directly related to the ways information is searched, followed, used and produced. The need for new easy to use services or tools for searching and following information in so called “hot” topics came apparent.  The study highlights new information about information practices in the biomedical domain. Whitley’s theory enabled a thorough analysis of the cultural and social nature of the biomedical domain and it proved to be useful in the examination of researchers’ information practices.
Enabling and Measuring Electronic Customer Relationship Management Readiness

This work provides a comprehensive customer-focused evaluation framework that businesses can use to assess their electronic customer relationship management (eCRM) readiness. The framework is intended to provide a big picture of the overall composition of e-CRM, to facilitate gap analysis, and to support a monitoring and feedback process. Knowledge management, trust, and technology are identified as key enablers of e-CRM. Finally, we propose weighting and rating scales to aid in assessing customer relationship management readiness, and provide examples of their use.
Survey Toward a Smart Campus Using the Internet of Things

IoT with its ability to make objects be sensed and connected is inevitable in the smart campus market. Even though the smart campus market has not taken off yet, there is an enormous research that is going on now all over the world to explore such technology. Several factors are driving investigators to study smart campus including: deliver high quality services, protect the environment, and save cost. In this paper, not only we explore the research conducted in this area, but we also investigate challenges and provide possible research opportunities regarding smart campus.
A keyed-hashing based self-synchronization mechanism for port address hopping communication

Port address hopping (PAH) communication is a powerful network moving target defense (MTD) mechanism. It was inspired by frequency hopping in wireless communications. One of the critical and difficult issues with PAH is synchronization. Existing schemes usually provide hops for each session lasting only a few seconds/minutes, making them easily influenced by network events such as transmission delays, traffic jams, packet dropouts, reordering, and retransmission. To address these problems, in this paper we propose a novel self-synchronization scheme, called ‘keyed-hashing based self-synchronization (KHSS)’. The proposed method generates the message authentication code (MAC) based on the hash based MAC (HMAC), which is then further used as the synchronization information for port address encoding and decoding. Providing the PAH communication system with one-packet-one-hopping and invisible message authentication abilities enables both clients and servers to constantly change their identities as well as perform message authentication over unreliable communication mediums without synchronization and authentication information transmissions. Theoretical analysis and simulation and experiment results show that the proposed method is effective in defending against man-in-the-middle (MITM) attacks and network scanning. It significantly outperforms existing schemes in terms of both security and hopping efficiency.
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis

Uric acid (UA) is the end product of purine metabolism and can reportedly act as an antioxidant. However, recently, numerous clinical and basic research approaches have revealed close associations of hyperuricemia with several disorders, particularly those comprising the metabolic syndrome. In this review, we first outline the two molecular mechanisms underlying inflammation occurrence in relation to UA metabolism; one is inflammasome activation by UA crystallization and the other involves superoxide free radicals generated by xanthine oxidase (XO). Importantly, recent studies have demonstrated the therapeutic or preventive effects of XO inhibitors against atherosclerosis and nonalcoholic steatohepatitis, which were not previously considered to be related, at least not directly, to hyperuricemia. Such beneficial effects of XO inhibitors have been reported for other organs including the kidneys and the heart. Thus, a major portion of this review focuses on the relationships between UA metabolism and the development of atherosclerosis, nonalcoholic steatohepatitis, and related disorders. Although further studies are necessary, XO inhibitors are a potentially novel strategy for reducing the risk of many forms of organ failure characteristic of the metabolic syndrome.
Overview of the Spinal Cord Injury – Quality of Life (SCI-QOL) measurement system

The Spinal Cord Injury--Quality of Life (SCI-QOL) measurement system was developed to address the shortage of relevant and psychometrically sound patient reported outcome (PRO) measures available for clinical care and research in spinal cord injury (SCI) rehabilitation. Using a computer adaptive testing (CAT) approach, the SCI-QOL builds on the Patient Reported Outcomes Measurement Information System (PROMIS) and the Quality of Life in Neurological Disorders (Neuro-QOL) initiative. This initial manuscript introduces the background and development of the SCI-QOL measurement system. Greater detail is presented in the additional manuscripts of this special issue.



Classical and contemporary test development methodologies were employed. Qualitative input was obtained from individuals with SCI and clinicians through interviews, focus groups, and cognitive debriefing. Item pools were field tested in a multi-site sample (n=877) and calibrated using item response theory methods. Initial reliability and validity testing was performed in a new sample of individuals with traumatic SCI (n=245).



Five Model SCI System centers and one Department of Veterans Affairs Medical Center across the United States.



Adults with traumatic SCI.



n/a



n/a



The SCI-QOL consists of 19 item banks, including the SCI-Functional Index banks, and 3 fixed-length scales measuring physical, emotional, and social aspects of health-related QOL (HRQOL).



The SCI-QOL measurement system consists of psychometrically sound measures for individuals with SCI. The manuscripts in this special issue provide evidence of the reliability and initial validity of this measurement system. The SCI-QOL also links to other measures designed for a general medical population.
Smart mobility management for D2D communications in 5G networks

Direct device-to-device (D2D) communications is regarded as a promising technology to provide low-power, high-data rate and low-latency services between end-users in the future 5G networks. However, it may not always be feasible to provide low-latency reliable communication between end-users due to the nature of mobility. For instance, the latency could be increased when several controlling nodes have to exchange D2D related information among each other. Moreover, the introduced signaling overhead due to D2D operation need to be minimized. Therefore, in this paper, we propose several mobility management solutions with their technical challenges and expected gains under the assumptions of 5G small cell networks.
Quantitative analysis of histological tissue image based on cytological profiles and spatial statistics

The cellular heterogeneity and complex tissue architecture of most tumor samples is a major obstacle in image analysis on standard hematoxylin and eosin-stained (H&E) tissue sections. A mixture of cancer and normal cells complicates the interpretation of their cytological profiles. Furthermore, spatial arrangement and architectural organization of cells are generally not reflected in cellular characteristics analysis. To address these challenges, first we describe an automatic nuclei segmentation of H&E tissue sections. In the task of deconvoluting cellular heterogeneity, we adopt Landmark based Spectral Clustering (LSC) to group individual nuclei in such a way that nuclei in the same group are more similar. We next devise spatial statistics for analyzing spatial arrangement and organization, which are not detectable by individual cellular characteristics. Our quantitative, spatial statistics analysis could benefit H&E section analysis by refining and complementing cellular characteristics analysis.
A randomized, double-blind, placebo-controlled trial of desvenlafaxine succinate in adult outpatients with major depressive disorder.

This study evaluated the efficacy and tolerability of desvenlafaxine succinate (desvenlafaxine) in the treatment of major depressive disorder (MDD).



In this 8-week, multicenter, randomized, double-blind, placebo-controlled trial, adult outpatients (aged 18-75 years) with a primary diagnosis of MDD (DSM-IV criteria) were randomly assigned to treatment with desvenlafaxine (100-200 mg/day) or placebo. The primary outcome measure was the 17-item Hamilton Rating Scale for Depression (HAM-D(17)) score at final on-therapy evaluation. The Clinical Global Impressions-Improvement scale (CGI-I) was the key secondary measure. Other secondary measures included the Montgomery-Asberg Depression Rating Scale (MADRS), Clinical Global Impressions-Severity of Illness scale, Visual Analog Scale-Pain Intensity (VAS-PI) overall and subcomponent scores, and HAM-D(17) response and remission rates. The study was conducted from June 2003 to May 2004.



Of the 247 patients randomly assigned to treatment, 234 comprised the intent-to-treat population. Following titration, mean daily desvenlafaxine doses ranged from 179 to 195 mg/day. At endpoint, there were no significant differences in scores between the desvenlafaxine (N = 120) and placebo (N = 114) groups on the HAM-D(17) or CGI-I. However, the desvenlafaxine group had significantly greater improvement in MADRS scores (p = .047) and in VAS-PI overall pain (p = .008), back pain (p = .006), and arm, leg, or joint pain (p < .001) scores than the placebo group. The most common treatment-emergent adverse events (at least 10% and twice the rate of placebo) were nausea, dry mouth, constipation, anorexia, somnolence, and nervousness.



Desvenlafaxine was generally safe and well tolerated. In this study, it did not show significantly greater efficacy than placebo on the primary or key secondary efficacy endpoints, but it did demonstrate efficacy on an alternate depression scale and pain measure associated with MDD.



ClinicalTrials.gov identifier NCT00063206.
A catastrophe model of anxiety and performance.

An experiment is reported which tests Fazey & Hardy's (1988) catastrophe model of anxiety and performance. Eight experienced basketball players were required to perform a set shooting task, under conditions of high and low cognitive anxiety. On each of these occasions, physiological arousal was manipulated by means of physical work in such a way that subjects were tested with physiological arousal increasing and decreasing. Curve-fitting procedures followed by non-parametric tests of significance confirmed (p less than .002) Fazey & Hardy's hysteresis hypothesis: namely, that the polynomial curves for the increasing vs. decreasing arousal conditions would be horizontally displaced relative to each other in the high cognitive anxiety condition, but superimposed on top of one another in the low cognitive anxiety condition. Other non-parametric procedures showed that subjects' maximum performances were higher, their minimum performances lower, and their critical decrements in performance greater in the high cognitive anxiety condition than in the low cognitive anxiety condition. These results were taken as strong support for Fazey & Hardy's catastrophe model of anxiety and performance. The implications of the model for current theorizing on the anxiety-performance relationship are also discussed.
What's in an Instance?

The notion of an instance is ubiquitous in knowledge representations for domain modeling. Most languages used for domain modeling offer syntactic or semantic restrictions on specific language constructs that distinguish individuals and classes in the application domain. The use, however, of instances and classes to represent domain entities has been driven by concerns that range from the strictly practical (e.g. the exploitation of inheritance) to the vaguely philosophical (e.g. intuitive notions of intension and extension). We demonstrate the importance of establishing a clear ontological distinction between instances and classes, and then show modeling scenarios where a single object may best be viewed as a class and an instance. To avoid ambiguous interpretations of such objects, it is necessary to introduce separate universes of discourse in which the same object exists in different forms. We show that a limited facility to support this notion exists in modeling languages like Smalltalk and CLOS, and argue that a more general facility should be made explicit in modeling languages.
Associations Between Physical Activity , Physical Fitness , and Falls Risk in Healthy Older Individuals

ASSOCIATIONS BETWEEN PHYSICAL ACTIVITY, PHYSICAL FITNESS, AND FALLS RISK IN HEALTHY OLDER INDIVIDUALS Christopher Deane Vaughan Old Dominion University, 2016 Chair: Dr. John David Branch  The purpose of this study was to assess relationships between objectively measured physical activity, physical fitness, and the risk of falling.  A total of n=29 subjects completed the study, n=15 male and n=14 female age (mean±SD)= 70± 4 and 71±3 years, respectively. In a single testing session, subjects performed pre-post evaluations of falls risk (Short-from PPA) with a 6-minute walking intervention between the assessments. The falls risk assessment included tests of balance, knee extensor strength, proprioception, reaction time, and visual contrast. The sub-maximal effort 6-minute walking task served as an indirect assessment of cardiorespiratory fitness. Subjects traversed a walking mat to assess for variation in gait parameters during the walking task. Additional center of pressure (COP) balance measures were collected via forceplate during the falls risk assessments. Subjects completed a Modified Falls Efficacy Scale (MFES) falls confidence survey. Subjects’ falls histories were also collected. Subjects wore hip mounted accelerometers for a 7-day period to assess time spent in moderate to vigorous physical activity (MVPA).  Males had greater body mass and height than females (p=0.001, p=0.001). Males had a lower falls risk than females at baseline (p=0.043) and post-walk (p=0.031). MFES scores were similar among all subjects (Median = 10). Falls history reporting revealed; fallers (n=8) and non-fallers (n=21). No significant relationships were found between main outcome measures of MVPA, cardiorespiratory fitness, or falls risk. Fallers had higher knee extensor strength than non-fallers at baseline (p=0.028) and post-walk (p=0.011). Though not significant (p=0.306), fallers spent 90 minutes more time in MVPA than non-fallers (427.8±244.6 min versus 335.7±199.5). Variations in gait and COP variables were not significant.  This study found no apparent relationship between objectively measured physical activity, indirectly measured cardiorespiratory fitness, and falls risk.
An overview of botulinum toxins: past, present, and future.

Although the mechanism of action of botulinum toxin (BTX) has been intensively studied, many unanswered questions remain regarding the composition and clinical properties of the two formulations of BTX currently approved for cosmetic use. In the first half of this review, these questions are explored in detail, with emphasis on the most pertinent and revelatory studies in the literature. The second half delineates most of the common and some not so common uses of BTX in the face and neck, stressing important patient selection and safety considerations. Complications from neurotoxins at cosmetic doses are generally rare and usually technique dependent.
ESP: Labeling Images with a Computer Game

We present a new interactive system: a game that is fun and can be used to create valuable output. When people play the game they help determine the contents of images by providing meaningful labels for them. If the game is played as much as popular online games, we estimate that most images on the Web can be labeled in a few months. Having proper labels associated with each image on the Web would allow for more accurate image search, would improve the accessibility of sites (by providing descriptions of images to visually impaired individuals), and would help users block inappropriate images. Our system makes a significant contribution because of its valuable output and because of the way it addresses the image-labeling problem. Rather than using computer vision techniques, which don’t work well enough, we encourage people to do the work by taking advantage of their desire to be entertained.
Regulatory Networks in Pollen Development under Cold Stress

Cold stress modifies anthers' metabolic pathways to induce pollen sterility. Cold-tolerant plants, unlike the susceptible ones, produce high proportion of viable pollen. Anthers in susceptible plants, when exposed to cold stress, increase abscisic acid (ABA) metabolism and reduce ABA catabolism. Increased ABA negatively regulates expression of tapetum cell wall bound invertase and monosaccharide transport genes resulting in distorted carbohydrate pool in anther. Cold-stress also reduces endogenous levels of the bioactive gibberellins (GAs), GA4 and GA7, in susceptible anthers by repression of the GA biosynthesis genes. Here, we discuss recent findings on mechanisms of cold susceptibility in anthers which determine pollen sterility. We also discuss differences in regulatory pathways between cold-stressed anthers of susceptible and tolerant plants that decide pollen sterility or viability.
Clinicopathological features and prognostic significance of CXCL12 in blastic plasmacytoid dendritic cell neoplasm.

Blastic plasmacytoid dendritic cell neoplasm (BPDC) is a rare hematologic neoplasm, which almost always involves the skin and shows poor prognosis.



The aim of our study was to enhance BPDC diagnosis and indications for prognosis.



This study involved 26 patients with BPDC. To investigate the histogenesis of BPDC, we reviewed the clinical features and stained markers of various hematopoietic lineages, chemokines, and their receptors.



Bone-marrow infiltration was detected in 13 of the 19 cases examined and leukemic changes in 18. Complete remission was achieved in 14 cases, but more than half of the patients showed recurrence within a short time, and 14 patients died of the disease after 1 to 25 months (mean 8.5 months). Positivity for CD123 was detected in 18 of 24 cases and for T-cell leukemia 1 in 18 of 22 cases. Of the chemokines and their receptors, 8 of 15 skin biopsy specimens proved to be positive for CXCL12. Leukemic change subsequent to skin lesions occurred in 7 of 8 CXCL12-positive cases (87.5%) and in 3 of 6 CXCL12-negative cases (50%). Seven of the 8 CXCL12-positive patients (87.5%) and two of the 6 CXCL12-negative patients (33.3%) have died, whereas one of 8 CXCL12-positive patients (12.5%) and 4 of 6 CXCL12-negative patients (66.7%) remain alive.



The number of patients was limited.



We speculate that the presence of CXCL12-positive cells in the skin may be associated with leukemic change and a poor prognosis.
AppShell: Making data protection practical for lost or stolen Android devices

Mobile apps continue to consume increasing amounts of sensitive data, such as banking credentials and classified documents. At the same time, the number of smartphone thefts is increasing at a rapid speed. As a result, there is an imperative need to protect sensitive data on lost or stolen mobile devices. In this work, we develop a practical solution to protect sensitive data on mobile devices. Our solution enables adaptive protection by pro-actively stepping up or stepping down data security based on perceived contextual risk of the device. We realize our solution for the Android platform in the form of a system called AppShell. AppShell does not require root privilege, nor need any modification to the underlying framework, and hence is a ready-to-deploy solution. It supports both in-memory and on-disk data protection by transparently encrypting the data, and discarding the encryption key, when required, for enhanced protection. We implement a working prototype of AppShell and evaluate it against several popular Android apps. Our results show that AppShell can successfully protect sensitive data in the lost devices with a reasonable performance overhead.