nils-herrmann/clean_scirepeval huggingface dataset:
ANTIMICROBIAL RESISTANCE , INTEGRON , VIRULENCE GENE , AND MULTILOCUS SEQUENCE TYPING OF ESCHERICHIA COLI ISOLATES FROM POSTWEANING PIGLETS WITH AND WITHOUT DIARRHEA

Pathogenic Escherichia coli is a major cause of diarrhea in postweaning piglets. Virulence genes, antimicrobial resistance, integrons, and genetic diversity of E. coli were determined in 100 rectal swab samples collected from postweaning piglets with and without diarrhea (5-7 weeks of age) in a farm in a central province of Thailand. Of 246 E. coli isolates, 141 were positive for at least one virulence gene determined by multiplex PCR, the most commonly found from both groups of piglets being astA, while lt, F4, F18, and F41 only from diarrheal piglets. More than 80% of E. coli isolates were resistant to 7 of 12 antimicrobial agents. One hundred and fifty-seven E. coli isolates carried class 1 and/or 2 integron(s). Integron-positive isolates are significantly associated with strains resistant to kanamycin, oxytetracycline, streptomycin, sulfamethoxazole/trimethoprim and tetracycline. Phylogenetic analysis by multilocus sequence typing revealed that the 31 representative E. coli isolates were genetically diverse, especially those from diarrheal piglets suggesting that E. coli from postweaning piglets were not derived from a single clone. Sequence type (ST)10, ST641 and ST1114 were most commonly found in both groups of piglets. No correlation was observed among ST, presence of integron and antimicrobial resistance. The study suggests that swines in a farm could be a reservoir and possible spread of diarrheagenic E. coli including strains with antimicrobial resistance genes.
Effectiveness of Triamcinolone Hexacetonide Intraarticular Injection in Interphalangeal Joints: A 12-week Randomized Controlled Trial in Patients with Hand Osteoarthritis.

To evaluate the effectiveness and tolerance of intraarticular injection (IAI) of triamcinolone hexacetonide (TH) for the treatment of osteoarthritis (OA) of hand interphalangeal (IP) joints.



Sixty patients who underwent IAI at the most symptomatic IP joint were randomly assigned to receive TH/lidocaine (LD; n = 30) with TH 20 mg/ml and LD 2%, or just LD (n = 30). The injected joint was immobilized with a splint for 48 h in both groups. Patients were assessed at baseline and at 1, 4, 8, and 12 weeks by a blinded observer. The following variables were assessed: pain at rest [visual analog scale (VAS)r], pain at movement (VASm), swelling (physician VASs), goniometry, grip and pinch strength, hand function, treatment improvement, daily requirement of paracetamol, and local adverse effects. The proposed treatment (IAI with TH/LD) was successful if statistical improvement (p < 0.05) was achieved in at least 2 of 3 VAS. Repeated-measures ANOVA test was used to analyze intervention response.



Fifty-eight patients (96.67%) were women, and the mean age was 60.7 years (± 8.2). The TH/LD group showed greater improvement than the LD group for VASm (p = 0.014) and physician VASs (p = 0.022) from the first week until the end of the study. In other variables, there was no statistical difference between groups. No significant adverse effects were observed.



The IAI with TH/LD has been shown to be more effective than the IAI with LD for pain on movement and joint swelling in patients with OA of the IP joints. Regarding pain at rest, there was no difference between groups.
4 Reject Brines from Desalination as Possible Sources for Environmental Technologies

Desalination of seawater represents the way to increase the supply of water for domestic, agricultural and industrial purposes. The potential environmental impact of desalination needs to be thoroughly evaluated, and any environmentally adverse consequences must be promptly addressed in order to assure a sustainable development of this technology. The main concern in desalination is the management of the brines whose uncontrolled discharge has significant negative impacts on the environment. Indeed, even if the production costs have decreased in the last decade, those related to the disposal of the brine have shown only limited reduction of the relative costs. New production strategies benefit from modern and efficient freshwater-generation plants, but the management strategies are based only on the few traditional options for the disposal of wastes. Sustainability is currently a main focus of high-level political discussions in the world, as it directly involves environmental pollution and global warming. Economic geologists are very well placed to understand and contribute to issues of sustainability, and to evaluate alternative resources for the future development of humanity. We, as economic geologists, are trained to unravel the complex series of events that led to the formation of natural resources. Consequently, we can use this expertise to help develop manmade processes to convert waste into resources. Today, the challenge is to consider the brine, instead of a harmful by-product, as a valuable source for several compounds to be involved in diverse industrial processes. For example, the brines could provide significant amounts of magnesium, resulting in a very promising source of this element as an alternative to traditional mining. Indeed, today there are stringent regulations concerning mining in all most all countries to prevent or at least minimize damage to exploited properties. As traditional approaches in mining are costly in time or inapplicable in abandoned and remote regions, research needs to be focused on nontraditional sources such as brines coming from desalination plants. These brines certainly have several advantages, and in time can replace, at least in part, the conventional sources with an alternative, economically attractive process. Dual benefits can be achieved in recovering and recycling Mg from reject brines: reduction of large volumes of brines to be
Wyrm: A Brain-Computer Interface Toolbox in Python

In the last years Python has gained more and more traction in the scientific community. Projects like NumPy, SciPy, and Matplotlib have created a strong foundation for scientific computing in Python and machine learning packages like scikit-learn or packages for data analysis like Pandas are building on top of it. In this paper we present Wyrm ( https://github.com/bbci/wyrm ), an open source BCI toolbox in Python. Wyrm is applicable to a broad range of neuroscientific problems. It can be used as a toolbox for analysis and visualization of neurophysiological data and in real-time settings, like an online BCI application. In order to prevent software defects, Wyrm makes extensive use of unit testing. We will explain the key aspects of Wyrm’s software architecture and design decisions for its data structure, and demonstrate and validate the use of our toolbox by presenting our approach to the classification tasks of two different data sets from the BCI Competition III. Furthermore, we will give a brief analysis of the data sets using our toolbox, and demonstrate how we implemented an online experiment using Wyrm. With Wyrm we add the final piece to our ongoing effort to provide a complete, free and open source BCI system in Python.
Effectiveness of Manual Therapy Combined With Physical Therapy in Treatment of Patellofemoral Pain Syndrome: Systematic Review.

The purpose of this study was to conduct a review of randomized controlled trials (RCTs) to determine the treatment effectiveness of the combination of manual therapy (MT) with other physical therapy techniques.



Systematic searches of scientific literature were undertaken on PubMed and the Cochrane Library (2004-2014). The following terms were used: "patellofemoral pain syndrome," "physical therapy," "manual therapy," and "manipulation." RCTs that studied adults diagnosed with patellofemoral pain syndrome (PFPS) treated by MT and physical therapy approaches were included. The quality of the studies was assessed by the Jadad Scale.



Five RCTs with an acceptable methodological quality (Jadad ≥ 3) were selected. The studies indicated that MT combined with physical therapy has some effect on reducing pain and improving function in PFPS, especially when applied on the full kinetic chain and when strengthening hip and knee muscles.



The different combinations of MT and physical therapy programs analyzed in this review suggest that giving more emphasis to proximal stabilization and full kinetic chain treatments in PFPS will help better alleviation of symptoms.
Decentralized User-Centric Access Control using PubSub over Blockchain

We present a mechanism that puts users in the center of control and empowers them to dictate the access to their collections of data. Revisiting the fundamental mechanisms in security for providing protection, our solution uses capabilities, access lists, and access rights following well-understood formal notions for reasoning about access. This contribution presents a practical, correct, auditable, transparent, distributed, and decentralized mechanism that is well-matched to the current emerging environments including Internet of Things, smart city, precision medicine, and autonomous cars. It is based on well-tested principles and practices used in distributed authorization, cryptocurrencies, and scalable computing.
Viable Algorithmic Options for Designing Reactive Robot Swarms

A central problem in swarm robotics is to design a controller that will allow the member robots of the swarm to collectively perform a given task. Of particular interest in massively distributed applications are reactive controllers with severely limited computational and sensory abilities. In this article, we give the results of the first computational complexity analysis of the reactive swarm design problem. Our core results are derived relative to a generalization of what is arguably the simplest possible type of reactive controller, the so-called computation-free controller proposed by Gauci et al., which operates in grid-based environments in a noncontinuous manner. We show that the design of a generalized computation-free swarm for an arbitrary given task in an arbitrary given environment is not polynomial-time solvable either in general or by the most desirable types of approximation algorithms (including evolutionary algorithms with high probabilities of producing correct solutions) but is solvable in effectively polynomial time relative to several types of restrictions on swarms, environments, and tasks. All of our results hold for the design of several more complex types of generalized computation-free swarms. Moreover, all of our intractability and inapproximability results hold for the design of any type of reactive swarm (including those based on the popular feed-forward neural network and Brooks-style subsumption controllers) operating in grid-based environments in a noncontinuous manner whose member robots satisfy two simple conditions. As such, our results give the first theoretical survey of the types of efficient exact and approximate solution algorithms that are and are not possible for designing several types of reactive swarms.
First-line treatment in senior adults with metastatic castration-resistant prostate cancer: A prospective international registry.

To compare the efficacy and tolerability of taxane and nontaxane therapy in senior adults with chemonaïve metastatic castration-resistant prostate cancer (mCRPC), and examine the effect of patient health status on outcomes.



Between 2009 and 2011, 333 patients aged≥70 years with mCRPC were enrolled in a prospective international registry. Patients were categorized as having received taxane-based or nontaxane therapy, and classified as fit, vulnerable, frail, or terminal, according to investigator judgement or International Society of Geriatric Oncology guidelines. Efficacy measures included overall survival (OS) and progression-free survival. Grade 3/4 toxicities were recorded. Predictors of OS were identified using multivariate Cox regression.



The proportions of fit/vulnerable/frail patients were 65%/14%/17% (International Society of Geriatric Oncology), and 39%/43%/17% (investigator). In single-factor analyses, taxane therapy improved OS (hazard ratio [95%CI] = 0.53 [0.30-0.93]; P = 0.027) and progression-free survival (hazard ratio [95% CI] = 0.55 [0.40-0.76]; P<0.001) vs. nontaxane therapy. Patients with frailty also benefited from taxane therapy (adapted regimen in 52%). In multivariate analysis, taxanes improved OS even with poor prognostic factors present (P = 0.017); age was unrelated to prognosis. Taxane therapy was well tolerated; most common grade 3/4 toxicities (taxane vs. nontaxane) were fatigue (17% vs. 4%), nausea/vomiting (14% vs. 5%) and neutropenia (10% vs. 1%).



The results of this nonrandomized, observational study suggest that first-line taxane therapy may benefit senior adults with mCRPC more than alternative therapies. Treatment decisions should not be based on chronological age.
Quantum Circuit Simplification and Level Compaction

Quantum circuits are time-dependent diagrams describing the process of quantum computation. Usually, a quantum algorithm must be mapped into a quantum circuit. Optimal synthesis of quantum circuits is intractable, and heuristic methods must be employed. With the use of heuristics, the optimality of circuits is no longer guaranteed. In this paper, we consider a local optimization technique based on templates to simplify and reduce the depth of nonoptimal quantum circuits. We present and analyze templates in the general case and provide particular details for the circuits composed of NOT, CNOT, and controlled-sqrt-of-NOT gates. We apply templates to optimize various common circuits implementing multiple control Toffoli gates and quantum Boolean arithmetic circuits. We also show how templates can be used to compact the number of levels of a quantum circuit. The runtime of our implementation is small, whereas the reduction in the number of quantum gates and number of levels is significant.
Gender, writing and ranking in review forums: a case study of the IMDb

Online review forums provide consumers with essential information about goods and services by facilitating word-of-mouth communication. Despite that preferences are correlated to demographic characteristics, reviewer gender is not often provided on user profiles. We consider the case of the internet movie database (IMDb), where users exchange views on movies. Like many forums, IMDb employs collaborative filtering such that by default, reviews are ranked by perceived utility. IMDb also provides a unique gender filter that displays an equal number of reviews authored by men and women. Using logistic classification, we compare reviews with respect to writing style, content and metadata features. We find salient differences in stylistic features and content between reviews written by men and women, as predicted by sociolinguistic theory. However, utility is the best predictor of gender, with women’s reviews perceived as being much less useful than those written by men. While we cannot observe who votes at IMDb, we do find that highly rated female-authored reviews exhibit “male” characteristics. Our results have implications for which contributions are likely to be seen, and to what extent participants get a balanced view as to “what others think” about an item.
Implementation of the MTPA and MTPV control with online parameter identification for a high speed IPMSM used as traction drive

In this paper, the problem of how to implement the MTPA/MTPV control for an energy efficient operation of a high speed Interior Permanent Magnet Synchronous Motor (IPMSM) used as traction drive is considered. This control method depends on the inductances Ld, Lq, the flux linkage ΨPM and the stator resistance Rs which might vary during operation. The parameter variation causes miscalculation of the set point currents Id and Iq for the inner current control system and thus a wrong torque will be set. Consequently the IPMSM will not be operating in the optimal operation point which yields to a reduction of the total energy efficiency and the performance. As a consequence, this paper proposes the implementation of the the Recursive Least Square Estimation (RLS) for a high speed and high performance IPMSM. With this online identification method the variable parameters are estimated and adapted to the MTPA and MTPV control strategy.
Neonatal infections due to multi-resistant strains: Epidemiology, current treatment, emerging therapeutic approaches and prevention.

Severe infections represent the main cause of neonatal mortality accounting for more than one million neonatal deaths worldwide every year. Antibiotics are the most commonly prescribed medications in neonatal intensive care units. The benefits of antibiotic therapy when indicated are clearly enormous, but the continued and widespread use of antibiotics has generated over the years a strong selective pressure on microorganisms, favoring the emergence of resistant strains. Health agencies worldwide are galvanizing attention toward antibiotic resistance in gram-positive and gram-negative bacteria. Infections in neonatal units due to multidrug and extensively multidrug resistant bacteria are rising and are already seriously challenging antibiotic treatment options. While there is a growing choice of agents against multi-resistant gram-positive bacteria, new options for multi-resistant gram-negative bacteria in the clinical practice have decreased significantly in the last 20 years making the treatment of infections caused by multidrug-resistant pathogens challenging mostly in neonates. Treatment options are currently limited and will be some years before any new treatment for neonates become available for clinical use, if ever. The aim of the review is to highlight the current knowledge on antibiotic resistance in the neonatal population, the possible therapeutic choices, and the prevention strategies to adopt in order to reduce the emergency and spread of resistant strains.
An enhancement transient response of capless LDO with improved dynamic biasing control for SoC applications

This paper presents an enhancement transient capless low dropout voltage regulator (LDO). To eliminate the external capacitor, the miller effect is implemented through the use of a current amplifier. The proposed regulator LDO provides a load current of 50 mA with a dropout voltage of 200 mV, consuming 14μA quiescent current at light loads, and the regulated output voltage is 1.6 V with an input voltage range from 1.2 to 1.8 V. The proposed system is designed in 0.18 μm CMOS technology. A folded cascode amplifier with high transconductance and high power efficiency is proposed to improve the transient response of the LDO. In addition, multiloop feedback strategy employs a direct dynamic biasing technique to provide a high speed path during the load transient responses. The simulation results presented in this paper will be compared with other results of SoC LDOs demonstrate the advantage of the proposed topology.
A novel 24-GHz series-fed patch antenna array for radar system

A novel 24-GHz patch series-fed antenna array is presented for radar system. It consists of an 8×8 transmitting antenna array and two 8×4 co-aperture receiving antenna arrays, which can not only achieve good suppression of side lobes and high aperture efficiency, but also avoid ambiguity in angle measurement. The simulated results show that the gains of the transmitting and the receiving antenna arrays are respectively 20.9dBi and 15.9dBi, while the suppressions of side lobes in two planes are both over 20dB.
Brushless permanent magnet DC and AC motor and synchonous reluctance motor design for racing motorcycles

There is an increasing interest in electric transportation. Most large manufacturers now produce hybrid versions of their popular models and in some countries electric cycles and scooter are now popular. Motor sport is often used to develop technology and in this paper designs for electric racing motorcycles are addressed. These are in-frame motors (rather than hub motors which can affect handling and are not as powerful). Typically 10 to 12 kW-hours of batteries can be carried on the cycle and the batteries are almost exhausted at the end of a race. Therefore very high efficiency over a range of operation is needed, but also the motors need to be compact and have high torque density. This paper examines the use of permanent magnet motors and possible designs.
Graphical passwords: a survey

The most common computer authentication method is to use alphanumerical usernames and passwords. This method has been shown to have significant drawbacks. For example, users tend to pick passwords that can be easily guessed. On the other hand, if a password is hard to guess, then it is often hard to remember. To address this problem, some researchers have developed authentication methods that use pictures as passwords. In this paper, we conduct a comprehensive survey of the existing graphical password techniques. We classify these techniques into two categories: recognition-based and recall-based approaches. We discuss the strengths and limitations of each method and point out the future research directions in this area. We also try to answer two important questions: "Are graphical passwords as secure as text-based passwords?"; "What are the major design and implementation issues for graphical passwords?" This survey will be useful for information security researchers and practitioners who are interested in finding an alternative to text-based authentication methods
System-level performance analysis of embedded system using behavioral C/C++ model

Design iteration time in SoC design flow is reduced through performance exploration at a higher level of abstraction. This paper proposes an accurate and fast performance analysis method in early stage of design process using a behavioral model written in C/C++ language. We made a cycle-accurate but fast and flexible compiled instruction set simulator (ISS) and IP models that represent hardware functionality and performance. System performance analyzer configured by the target communication architecture analyzes the performance utilizing event-traces obtained by running the ISS and IP models. This solution is automated and implemented in the tool, HIPA. We obtain diverse performance profiling results and achieve 95% accuracy using an abstracted C model. We also achieve about 20 times speed-up over corresponding co-simulation tools.
Representing Control: A Study of the CPS Transformation

This paper investigates the transformation of v-terms into continuation-passing style (CPS). We show that by appropriate-expansion of Fischer and Plotkin's two-pass equational speciication of the CPS transform, we can obtain a static and context-free separation of the result terms into \essential" and \administrative" constructs. Interpreting the former as syntax builders and the latter as directly executable code, we obtain a simple and eecient one-pass transformation algorithm, easily extended to conditional expressions, recursive deenitions, and similar constructs. This new transformation algorithm leads to a simpler proof of Plotkin's simulation and indiierence results. We go on to show how CPS-based control operators similar to, but more general than, Scheme's call/cc can be naturally accommodated by the new transformation algorithm. To demonstrate the expressive power of these operators, we use them to present an equivalent but even more concise formulation of the eecient CPS transformation algorithm. Finally, we relate the fundamental ideas underlying this derivation to similar concepts from other works on program manipulation; we derive a one-pass CPS transformation of n-terms; and we outline some promising areas for future research.