nils-herrmann/clean_scirepeval huggingface dataset:
Frailty is independently associated with worse health related quality of life in chronic kidney disease: a secondary analysis of the Frailty Assessment in Chronic Kidney Disease study
Venue: Clinical kidney journal
Year: 2020

Understanding how frailty affects health related quality of life (HRQOL) in those with chronic kidney disease (CKD) could assist in the development of management strategies to improve outcomes for this vulnerable patient group. This study aimed to evaluate the relationship between frailty and HRQOL in patients with CKD Stages 4 and 5 (G4 5) and those established on haemodialysis (G5D)  Ninety participants with chronic kidney disease (CKD G4 5D) were recruited between December 2016 and December 2017. Frailty was assessed using the Frailty Phenotype, which included assessments of unintentional weight loss, weakness (handgrip strength) slowness (walking speed) physical activity and self perceived exhaustion. HRQOL was assessed using the RAND 36 Item Health Survey Version 1.0 (SF 36) Results Nineteen (21% patients were categorized as frail. Frailty, when adjusted for age, gender, dialysis dependence and comorbidity, had a significant effect on five of the eight SF 36 domains: physical functioning, role limitations due to emotional problems, energy/fatigue, social functioning and pain. Regression modelling best explained the variation in the physical functioning domain (adj. R2 0.27, P 0.001) with frailty leading to a 26 point lower score. Exhaustion was the only Frailty Phenotype component that had a significant effect on scores across all SF 36 domains.  Frailty is independently associated with worse HRQOL in patients with CKD G4 5D, with self perceived exhaustion being the most significant Frailty Phenotype component contributing to HRQOL. Efforts should be made to identify frail patients with CKD so that management strategies can be offered that aim to improve morbidity, mortality and patient reported outcomes, including HRQOL and fatigue.
Alterations of the microRNA network cause neurodegenerative disease
Venue: Trends in Neurosciences
Year: 2009

Brain development crucially depends on the integrity of microRNA (miRNA) pathways, which function at the post transcriptional level as a rheostat of the transcriptome and proteome of the cell. miRNAs are also involved in many other, more specific, aspects of neuronal function such as neurite outgrowth and synapse formation. Complete loss of miRNA expression in the brain leads to neurodegeneration in several animal models. Evidence from patient material is emerging that miRNA dysregulation could, indeed, contribute to neurodegenerative disorders. The translation of proteins previously implicated in familial forms of disease seems to be under control of miRNAs, and changes in miRNAs might explain how these proteins become affected in sporadic neurodegenerative disease. Thus, miRNAs are moving rapidly center stage as key regulators of neuronal development and function in addition to important contributors to neurodegenerative disorder.
Applying Augmented Reality to Consumer Garment Try On Experience
Venue: Trans. Comput. Sci.
Year: 2011

Experience in this paper refers to the sentimental episode of consumers through service. Through experience or service, consumers can reach their internal sentiment. In terms of the general garment try on, if consumers cannot experience the practical atmosphere, then they would not be able to determine whether the garment fits to their likings. When people see the available garment styles and sizes from virtual try on rooms, it still does not provide consumers with actual experience sentiment. However, the augmented reality (AR) is an extension of virtual reality (VR) and it emphasizes the realtime interaction with the experience under real environment. In this paper, it placed the focus on consumer garment try on experience which is integrated with AR and adopted the theory of graphical user interface (GUI) to process the design of Graphic vision and interface. Through the construction of AR systems, the interaction between operation models and processes of consumer garment try on can be well improved. We rely on the theory of GUI to process the design of Graphic vision and interface, simulation and testing of the system, and evaluation of the interface is done by scale rule of usability engineering methods (UEMs) Also, the feedback on human machine interactive system (HMIS) perception, information, storage, decision making and mobile functions can be obtained with the reference available for upcoming effort in relevant garment digitalizing and consumer researches.
Evidencias psicometricas de una version breve de la Coping Humor Scale en adultos mayores peruanos
Venue: Revista Espanola de Geriatria y Gerontologia
Year: 2019

Resumen Introduccion El humor tiene un papel importante en la promocion de un envejecimiento exitoso y saludable. Sin embargo, su estudio cientifico es aun limitado, en parte debido a la ausencia de medidas validadas para su uso en el ambito latinoamericano. El objetivo del estudio fue traducir al espanol y examinar las evidencias de fiabilidad y validez basadas en la estructura interna, convergente y discriminante de la version peruana de la Coping with Humor Scale 5 items. Materiales y metodos Los participantes fueron 236 adultos mayores peruanos (78,4% mujeres y 21,6% hombres) con un promedio de edad de 72,8 anos (DE 6,90) Se realizo un analisis factorial confirmatorio, analisis de correlacion (r) y fiabilidad (a; alfa de cronbach y o; omega) Resultados El modelo unidimensional presento un ajuste adecuado de los datos (kh2 7,72, df 5, p 0,17, kh2/df 1,54, GFI =0,988, CFI =0,996, NFI 0,988; RMSEA 0,048 [IC90% 0,000, 0,111] y SRMR 0,016) Los indices de fiabilidad son adecuados (a= 0,86 [IC95% 0,82 0,89] y o 0,89 [IC95% 0,87 0,91] Se observa una correlacion positiva entre la puntuacion promedio de la CHS 5 y la satisfaccion con la vida, y negativa con la depresion. Conclusiones La CHS 5 presenta excelentes propiedades psicometricas, siendo una medida que brinda interpretaciones validas y confiables para ser utilizada en adultos mayores peruanos.
PENDEKATAN PERILAKU KEUANGAN TERHADAP KEPUTUSAN INVESTASI EMAS
Year: 2020

This research aims to analyze the influence of representativeness, overconfidence, anchoring, loss aversion, and regret aversion towards gold investment decision. S ample of this study are gold investors in Batam. Hypothesis test using multiple regression. Results from this research showed that investors used representativeness, overcinfidence, and loss aversion to determine their investment decision in gold. But anchoring and regret aversion factors have no significant impact in their investment decision. Further research for investment decision could be conducted in financial sector.
COVID 19 and Radiology Resident Imaging Volumes Differential Impact by Resident Training Year and Imaging Modality
Venue: Academic Radiology
Year: 2020

The COVID 19 pandemic has greatly impacted radiology departments across the country. The pandemic has also disrupted resident education, both due to departmental social distancing efforts and reduced imaging volumes. The purpose of this study was to assess the differential impact the pandemic had on radiology resident imaging volumes by training year and imaging modality.  All signed radiology resident reports were curated during defined pre pandemic and intra pandemic time periods. Imaging case volumes were analyzed on a mean per resident basis to quantify absolute and percent change by training level. Change in total volume by imaging modality was also assessed. The number of resident workdays assigned outside the normal reading room was also calculated.  Overall percent decline in resident imaging interpretation volume from the pre pandemic to intra pandemic time period was 62.8% R1s and R2s had the greatest decline in at 87.3% and 64.3% respectively. Mammography, MRI and nuclear medicine had the greatest decline in resident interpretation volume at 92.0% 73.2% and 73.0% respectively. During the intra pandemic time period, a total of 478 resident days (mean of 14.5 days per resident) were re assigned outside of the radiology reading room.  The COVID 19 pandemic caused a marked decrease in radiology resident imaging interpretation volume and has had a tremendous impact on resident education. The decrease in case interpretation, as well as in person teaching has profound implications for resident education. Knowledge of this differential decrease by training level will help residency programs plan for the future.
Automatic Fat Segmentation Method on Thigh MRI
Year: 2012

Fat research of thigh is very valuable in the diagnosis of metabolic syndrome and metabolic dysfunction.However,it is more difficult to segment the subcutaneous fat and intermuscular fat in MRI images because of connected regions.The result of expectation maximization algorithm is used to improve level set algorithm and realize automatic MRI image segmentation.Results show that the subcutaneous fat tissue,intermuscular fat tissue,and other tissues of thigh can be successfully segmented with the method.
Impacto do bruxismo no limiar de dor a pressao da musculatura mastigatoria de mulheres com migranea
Year: 2019

O bruxismo e definido como uma atividade repetitiva da musculatura mandibular, caracterizado por apertar ou ranger dos dentes e/ou apoiar ou empurrar a mandibula. Apesar da grande prevalencia da alta prevalencia de bruxismo entre pacientes com migranea, pouco se sabe sobre as implicacoes da associacao dessas comorbidades. Essa investigacao objetivou avaliar a prevalencia de bruxismo em mulheres com migranea episodica, bem como avaliar a influencia destes no limiar de dor a pressao da musculatura mastigatoria das mesmas. O presente estudo foi realizado em uma populacao com migranea associada ou nao a bruxismo do sono e em vigilia avaliando o Limiar de Dor a Pressao, atraves da algometria, em pacientes do sexo feminino. Foram avaliadas 250 candidatas e, dessas apenas 86 preencheram todos os pre requisitos exigidos pelos criterios de inclusao. As pacientes foram divididas em quatro grupos: grupo 1 (n=28) pacientes sem bruxismo; grupo 2 (n=17) pacientes com bruxismo em vigilia; grupo 3 (n=9) pacientes com bruxismo noturno e grupo 4 (n=32) pacientes com bruxismo em vigilia e noturno. O Qui quadrado foi utilizado para avaliar significancia quanto ao numero de pacientes com bruxismo na amostra e o teste T de Student para analisar o limiar de dor a pressao das pacientes. Nao houve diferenca estatisticamente significante entre os limiares do musculo temporal (p=0,25) e masseter (p=0,34) entre os grupos (sem e com bruxismo) Pode se concluir que o bruxismo nao influencia o limiar de dor a pressao de mulheres que possuem crises de migranea episodica.
Wavelet Based Finger Knuckle and Finger vein Authentication System
Year: 2016

Biometrics is the prominent technology for accurate and safe detection of claim identity. This paper proposes a novel multimodal authentication system using finger knuckle (FK) and finger vein (FV) Finger Knuckle has unique bending and makes this a distinctive biometric identifier. The vein pattern of all fingers of human being is not same. Each finger of same person has different vein pattern. It is the hidden part which is not seen by normal eye sight hence less possible to forge. The system consists of proposed prototype finger knuckle and finger vein image capturing devices, formation of own FK and FV image database acquired from proposed devices. Here feature extraction of FK images is based on Walsh Wavelet Transform and FV image on Hybrid Wavelet Transform. Proposed multimodal biometric authentications integrate transformed domain features vector of FK and FV at score level fusion using Bayesian and weighted sum method. The fusion of these two modalities using Bayesian method demonstrated the recognition accuracy of 98.3% and weighted sum 98.5 Various weights of finger knuckle and finger vein affects the recognition accuracy. The better recognition accuracy is obtained at weight of 0.8 and 0.2. The performance index is improved i.e 98.5% and the Error equal rate is 1.5% as compare to unimodal biometric. Error equal rate is reduced by 10% than individual biometric system. For N user with M 1 and M 2 as test and training samples, for verification of one user, matching complexity is O (M 1 M 2 and for N user O(M 1 M 2 x N) For identification, (N x M 1 test samples and (N x M 2 training samples are considered. So matching complexity is O [N (N 1) x M 1 for each biometric. Using conventional matching the complexity is O [N (N 1) x M 1 M 2 For multimodal biometric using FK and FV, matching complexity is O 2[N (N 1) x M 1 It shows great reduction in matching complexity using the proposed algorithms.
Re examination of Hofstede's work value orientations on perceived leadership styles in Jordan
Year: 2012

The purpose of this paper is to examine the impact of work values on leadership styles and to introduce new findings when Hofstede's work value orientations are applied to other different cultural domains (i.e. Jordan).Design/methodology/approach A survey of 235 Jordanian managers was undertaken using two instruments of measurement: the "Cultural Attitude Inventory" and the "T P Leadership Questionnaire: An Assessment of Style."Findings Results confirmed the anticipated relation between "task" leadership style and Jordanian managers' values of power distance and uncertainty avoidance, but they did not confirm the anticipated relation between "people" leadership style and collectivist values of Jordanian managers. The results have important implications for the management of international and transnational organizations who may need to consider whether promoting a consistent world wide leadership style would be more or less beneficial than adopting a style that matches the
Survival prediction in high grade gliomas using CT perfusion imaging
Venue: Journal of Neuro Oncology
Year: 2015

Patients with high grade gliomas usually have heterogeneous response to surgery and chemoirradiation. The objectives of this study were (1) to evaluate serial changes in tumor volume and perfusion imaging parameters and (2) to determine the value of these data in predicting overall survival (OS) Twenty nine patients with World Health Organization grades III and IV gliomas underwent magnetic resonance (MR) and computed tomography (CT) perfusion examinations before surgery, and 1, 3, 6, 9, and 12 months after radiotherapy. Serial measurements of tumor volumes and perfusion parameters were evaluated by receiver operating characteristic analysis, Cox proportional hazards regression, and Kaplan Meier survival analysis to determine their values in predicting OS. Higher trends in blood flow (BF) blood volume (BV) and permeability surface area product in the contrast enhancing lesions (CEL) and the non enhancing lesions (NEL) were found in patients with OS 18 months compared to those with OS 18 months, and these values were significant at selected time points (P 0.05) Only CT perfusion parameters yielded sensitivities and specificities of =70 in predicting 18 and 24 months OS. Pre surgery BF in the NEL and BV in the CEL and NEL 3 months after radiotherapy had sensitivities and specificities >80 in predicting 24 months OS in patients with grade IV gliomas. Our study indicated that CT perfusion parameters were predictive of survival and could be useful in assessing early response and in selecting adjuvant treatment to prolong survival if verified in a larger cohort of patients.
Using clinical Natural Language Processing for health outcomes research: Overview and actionable suggestions for future advances
Venue: J. Biomed. Informatics
Year: 2018

The importance of incorporating Natural Language Processing (NLP) methods in clinical informatics research has been increasingly recognized over the past years, and has led to transformative advances. Typically, clinical NLP systems are developed and evaluated on word, sentence, or document level annotations that model specific attributes and features, such as document content (e.g. patient status, or report type) document section types (e.g. current medications, past medical history, or discharge summary) named entities and concepts (e.g. diagnoses, symptoms, or treatments) or semantic attributes (e.g. negation, severity, or temporality) From a clinical perspective, on the other hand, research studies are typically modelled and evaluated on a patient or population level, such as predicting how a patient group might respond to specific treatments or patient monitoring over time. While some NLP tasks consider predictions at the individual or group user level, these tasks still constitute a minority. Owing to the discrepancy between scientific objectives of each field, and because of differences in methodological evaluation priorities, there is no clear alignment between these evaluation approaches. Here we provide a broad summary and outline of the challenging issues involved in defining appropriate intrinsic and extrinsic evaluation methods for NLP research that is to be used for clinical outcomes research, and vice versa. A particular focus is placed on mental health research, an area still relatively understudied by the clinical NLP research community, but where NLP methods are of notable relevance. Recent advances in clinical NLP method development have been significant, but we propose more emphasis needs to be placed on rigorous evaluation for the field to advance further. To enable this, we provide actionable suggestions, including a minimal protocol that could be used when reporting clinical NLP method development and its evaluation.
Maternal Kronik Hepatit B Virus Enfeksiyonu Gebelik ve Fetal Riskleri Artiriyor Mu?
Year: 2019

More than 400 million people worldwide are infected with the hepatitis B virus (HBV) The effect of HBV infection on pregnant women is unclear. The presence of chronic HBV in pregnancy has been reported to increase such maternal and fetal risks as gestational diabetes, antepartum hemorrhage, prematurity, neonatal jaundice, and low birth weight. The purpose of this study was to investigate the effects of HBV on pregnancy and fetal risks.  Three hundred and one pregnant women infected with HBV and giving live birth in our hospital in 2014 2017, and their babies, were enrolled as the case group, while randomly selected pregnant women giving live birth in our hospital and not infected with HBV, and their babies, were included as the control group. Maternal and fetal outcomes such as type of delivery, miscarriage, re eclampsia, gestational diabetes, antepartum hemorrhage, fetal distress, gestational weeks, and intrauterine growth restriction (IUGR) were analyzed retrospectively from patients' records.  Delivery was by the normal vaginal route in 189 (62.8% of the 301 HBsAg positive women in the study, while diabetes was present in 4 (1.3% pre eclampsia in 2 (0.7% a history of miscarriage in 82 (27.2% and placental detachment in 5 (1.7% No statistically significant difference was determined between these and the HBsAg negative women (p>0.05) IUGR was present in the babies of 6 (2% of HBsAg( mothers, and fetal distress in 12 (40% The presence of fetal distress was significantly higher in the babies of HBsAg( mothers (p:0.036)  Although several studies have shown that HBV infection increases maternal and fetal risks, only the risk of fetal distress was significant in our study. The noteworthy finding of our study is that the presence of HBV did not affect the physician's decision regarding type of delivery.
Investigations of the Underlying Mechanisms of HIF 1 a and CITED 2 Binding to TAZ 1 September 4 2019
Year: 2019

The TAZ1 domain of CREB binding protein is crucial for transcriptional regulation and recognizes multiple targets. The interactions between TAZ1 and its specific targets are related to the cellular hypoxic negative feedback regulation. Previous experiments reported that one of the TAZ1 targets CITED2 is an efficient competitor of another target HIF 1a Here by developing the structure based models of TAZ1 complexes we have uncovered the underlying mechanisms of the competitions between HIF 1a and CITED2 binding to TAZ1. Our results are consistent with the experimental hypothesis on the competition mechanisms and the apparent affinity. In addition, the simulations prove the dominant position of forming TAZ1 CITED2 complex in both thermodynamics and kinetics. For thermodynamics, TAZ1 CITED2 is the lowest basin located on the free energy surface of binding in the ternary system. For kinetics, the results suggest that CITED2 binds to TAZ1 faster than HIF 1a Besides, the analysis of contact map and ph values in this study will be helpful for further experiments on TAZ1 systems.
Greek preservice physical education teachers' mental models of production and reproduction teaching styles
Year: 2019

The purpose of this study was to examine Greek preservice physical education (PE) teachers' presuppositions, beliefs and mental models about the reproduction and production teaching styles. The participants were 16 preservice PE teachers (10 males, six females) A qualitative methodology was used with data collected using semi structured interviews. A multi level analysis process using open coding and axial coding was sequentially conducted. Findings revealed two generative mental models about teaching styles. For the first mental model (n 5) learning is considered as a transmissive and unidimensional (i.e. one goal pursued at a time) process. Presuppositions supported by this mental model urge the preservice teachers to believe that the reproduction teaching styles promote effective learning, class control, students' safety and discipline. For the second mental model (n 11) learning is viewed as a constructivist and multidimensional (i.e. multiple goals pursued at a time) process. Presuppositions supported by this mental model urge the participants to believe that the production teaching styles effectively promote students' learning, critical thinking, responsibility, motivation, autonomy and discipline. The aforementioned mental models highlight the developmental nature of preservice PE teachers' learning concerning the production and the reproduction teaching styles. These mental models reveal the diversity of PE preservice teachers' understanding of the teaching and learning processes. Furthermore, findings support Vosniadou's assumption that learners come to formal education not as a tabula rasa but holding a naive understanding about the world.