nils-herrmann/clean_scirepeval huggingface dataset:
Effect of Low Dose Ferrous Sulfate vs Iron Polysaccharide Complex on Hemoglobin Concentration in Young Children With Nutritional Iron Deficiency Anemia: A Randomized Clinical Trial
Venue: JAMA
Year: 2017

Iron deficiency anemia (IDA) affects millions of persons worldwide, and is associated with impaired neurodevelopment in infants and children. Ferrous sulfate is the most commonly prescribed oral iron despite iron polysaccharide complex possibly being better tolerated.  To compare the effect of ferrous sulfate with iron polysaccharide complex on hemoglobin concentration in infants and children with nutritional IDA.  Double blind, superiority randomized clinical trial of infants and children aged 9 to 48 months with nutritional IDA (assessed by history and laboratory criteria) that was conducted in an outpatient hematology clinic at a US tertiary care hospital from September 2013 through November 2015; 12 week follow up ended in January 2016.  Three mg/kg of elemental iron once daily as either ferrous sulfate drops or iron polysaccharide complex drops for 12 weeks.  Secondary outcomes included complete resolution of IDA (defined as hemoglobin concentration >11 g/dL, mean corpuscular volume >70 fL, reticulocyte hemoglobin equivalent >25 pg, serum ferritin level >15 ng/mL, and total iron binding capacity <425 &mgr;g/dL at the 12 week visit) changes in serum ferritin level and total iron binding capacity, adverse effects.  Of 80 randomized infants and children (median age, 22 months; 55% male; 61% Hispanic white; 40 per group) 59 completed the trial (28 [70% in ferrous sulfate group; 31 [78% in iron polysaccharide complex group) From baseline to 12 weeks, mean hemoglobin increased from 7.9 to 11.9 g/dL (ferrous sulfate group) vs 7.7 to 11.1 g/dL (iron complex group) a greater difference of 1.0 g/dL (95% CI, 0.4 to 1.6 g/dL; P .001) with ferrous sulfate (based on a linear mixed model) Proportion with a complete resolution of IDA was higher in the ferrous sulfate group (29% vs 6% P .04) Median serum ferritin level increased from 3.0 to 15.6 ng/mL (ferrous sulfate) vs 2.0 to 7.5 ng/mL (iron complex) over 12 weeks, a greater difference of 10.2 ng/mL (95% CI, 6.2 to 14.1 ng/mL; P .001) with ferrous sulfate. Mean total iron binding capacity decreased from 501 to 389 &mgr;g/dL (ferrous sulfate) vs 506 to 417 &mgr;g/dL (iron complex) (a greater difference of 50 &mgr;g/dL [95% CI, 86 to 14 &mgr;g/dL] with ferrous sulfate; P .001) There were more reports of diarrhea in the iron complex group than in the ferrous sulfate group (58% vs 35% respectively; P .04)  Among infants and children aged 9 to 48 months with nutritional iron deficiency anemia, ferrous sulfate compared with iron polysaccharide complex resulted in a greater increase in hemoglobin concentration at 12 weeks. Once daily, low dose ferrous sulfate should be considered for children with nutritional iron deficiency anemia.
From Finite Automata to Regular Expressions and Back A Summary on Descriptional Complexity
Venue: Int. J. Found. Comput. Sci.
Year: 2015

The equivalence of finite automata and regular expressions d ates back to the seminal paper of Kleene on events in nerve nets and finite automata from 1956. In the pr esent paper we tour a fragment of the literature and summarize results on upper and lower bounds on the conversion of finite automata to regular expressions and vice versa. We also briefly recall the known bounds for the removal of spontaneous transitions (e transitions) on non e free nondeterministic devices. Moreover, we report on recent results on the average case descriptional complexity bounds for the conversion of regular expressions to finite automata and brand new developments on the state elimination algorithm that converts finite automata to regular expressions.
Modified element stacking method for multi material topology optimization with anisotropic materials
Venue: Structural and Multidisciplinary Optimization
Year: 2019

This article presents a modified element stacking method for anisotropic multi material topology optimization. This method can transform standard multi material topology optimization formulations into a series of equivalent single material topology optimization ones to overcome the various limitations inherent to conventional techniques. First, typical multi material topology optimization methods utilize material interpolation schemes that restrict the study to the isotropic domain with a constant Poisson's ratio, limiting practical applications and solution accuracy. Additionally, in attempts to further extend these classical multi material topology optimization methods to anisotropic materials, preparing the necessary element information matrices becomes increasingly laborious or even impossible for complex models, preventing the application of sensitivity analysis for robust gradient based optimization methods. To directly address these limitations, the element interpolation method replaces material interpolation schemes with an element interpolation framework, where each design cell property is determined using a weighted sum of various coincident single material elements. This paper provides a thorough description of element interpolation and presents several numerical examples demonstrating successful implementation.
Adaptive Fuzzy Neural Network Control for a Constrained Robot Using Impedance Learning
Venue: IEEE Transactions on Neural Networks and Learning Systems
Year: 2018

This paper investigates adaptive fuzzy neural network (NN) control using impedance learning for a constrained robot, subject to unknown system dynamics, the effect of state constraints, and the uncertain compliant environment with which the robot comes into contact. A fuzzy NN learning algorithm is developed to identify the uncertain plant model. The prominent feature of the fuzzy NN is that there is no need to get the prior knowledge about the uncertainty and a sufficient amount of observed data. Also, impedance learning is introduced to tackle the interaction between the robot and its environment, so that the robot follows a desired destination generated by impedance learning. A barrier Lyapunov function is used to address the effect of state constraints. With the proposed control, the stability of the closed loop system is achieved via Lyapunov's stability theory, and the tracking performance is guaranteed under the condition of state constraints and uncertainty. Some simulation studies are carried out to illustrate the effectiveness of the proposed scheme.
KAJIAN YURIDIS TERHADAP PERATURAN PEMERINTAH NOMOR 45TAHUN 2014 TENTANG JENIS DAN TARIF ATAS JENISPENERIMAAN NEGARA BUKAN PAJAK YANG BERLAKU PADAKEMENTERIAN HUKUM DAN HAK ASASI MANUSIA(KHUSUSNYA TERHADAP PROFESI NOTARIS)
Year: 2015

Pembentukan Peraturan Pemerintah Nomor 45 Tahun 2014 tentang Jenis dan Tarif atas Jenis Penerimaan Negara Bukan Pajak yang berlaku pada Kementerian Hukum dan Hak Asasi Manusia yang memuat kenaikan tarif penerimaan negara bukan pajak yang sangat signifikan, khususnya dalam hal pengangkatan Notaris dirasakan tidak mencermikan asas keadilan sebagaimana diamanatkan oleh Undang Undang Nomor 20 Tahun 1997 tentang Penerimaan Negara Bukan Pajak yang merupakan payung hukum utama dalam pemungutan Penerimaan Negara Bukan Pajak. Demikian latar belakang dalam penulisan tesis ini. Kenaikan tarif penerimaan negara bukan pajak dalam peraturan pemerintah ini memunculkan pertanyaan, apakah dasar pemerintah menaikan tarif penerimaan negara bukan pajak terhadap pengangkatan notaris, dan apa implikasi terhadap diberlakukaknnya Peraturan Pemerintah ini. Penelitian ini menggunakan metode pendekatan yuridis empiris, yaitu penelitian yang tidak hanya meneliti normanya saja tetapi juga meneliti penerapan hukum (bekerjanya hukum) di masyarakat, sehingga tidak hanya meneliti bahan kepustakaan (data sekunder) yang berupa bahan bahan hukum, tetapi juga mengamati perilaku manusia dalam melaksanakan hukum. Kenaikan tarif penerimaan negara bukan pajak bertujuan untuk pemerataan formasi notaris, karena dengan dinaikannya tarif PNBP di kota kota besar diharapkan para calon notaris yang ingin berpraktek di kota kota besar berfikir ulang, sehingga mau berpraktek di daerah daerah, serta kemungkinan honorarium yang harus dibayarkan seseorang atau badan hukum pengguna jasa notaris mengalami kenaikan. Peraturan Pemerintah yang merupakan peraturan pelaksana dari Undang Undang, seharusnya dalam pembentukannya memperhatikan asas asas dalam Undang Undang, sebagai peraturan perundang undangan yang memiliki hierarki yang lebih tinggi
Knowledge Driven Stock Trend Prediction and Explanation via Temporal Convolutional Network
Venue: WWW
Year: 2019

Deep neural networks have achieved promising results in stock trend prediction. However, most of these models have two common drawbacks, including (i) current methods are not sensitive enough to abrupt changes of stock trend, and (ii) forecasting results are not interpretable for humans. To address these two problems, we propose a novel Knowledge Driven Temporal Convolutional Network (KDTCN) for stock trend prediction and explanation. Firstly, we extract structured events from financial news, and utilize external knowledge from knowledge graph to obtain event embeddings. Then, we combine event embeddings and price values together to forecast stock trend. We evaluate the prediction accuracy to show how knowledge driven events work on abrupt changes. We also visualize the effect of events and linkage among events based on knowledge graph, to explain why knowledge driven events are common sources of abrupt changes. Experiments demonstrate that KDTCN can (i) react to abrupt changes much faster and outperform state of the art methods on stock datasets, as well as (ii) facilitate the explanation of prediction particularly with abrupt changes.
Alendronate induced subacute cutaneous lupus erythematosus successfully treated with intravenous immunoglobulin
Venue: Dermatologic therapy
Year: 2020

The subacute cutaneous lupus erythematosus (SCLE) is a distinct subtype of lupus erythematosus (LE) representing specific clinical and serological features. Almost 20% 30% of the cases with SCLE are predicted to associated with medications. Thiazide diuretics, terbinafine, antiepileptic, and proton pump inhibitors are the best known drugs to induce drug related SCLE. Herein we want to present a 65 year old female with alendronate induced SCLE, resistant to classical therapies, and respond well to intravenous immunoglobulin (IVIG) suggesting that IVIG could be an alternative treatment in patients resistant to classical treatment protocols.
Dimension Formulas of Siegel Modular Forms of Weight 3 and Supersingular Abelian Surfaces Revised version
Year: 2018

In this article, first we give dimension formulas of the space S3(G) of Siegel cusp forms of weight 3 of degree 2 belonging to discrete subgroups G of parahoric type, including Hecke type groups G0(p) paramodular groups K(p) Klingen type groups G 0(p) and the Iwahori subgroup B(p) of any prime level. As for weight k 4, the dimension formulas for Siegel modular forms of degree two are explicitly known for many discrete subgroups and there are two well known methods to calculate these: the Riemann Roch Hirzebruch theorem for k 4 and the Selberg trace formula for k 5. Both methods does not work for weight k 3 in general and there are no general ways to calculate the dimension for k 3. Before our present work, the dimensions of S3(G) were calculated only for finitely many (conjugacy classes of) discrete subgroups by rather complicated technical numerical calculation depending heavily on each discrete group G (cf. e.g. Poor and Yuen  In this paper, we use holomorphic Lefschetz formula (a group invariant version of RiemannRoch Hirzebruch) The obstruction of the cohomology in this formula does not vanish in general, but by showing that it vanishes for the above discrete groups, we obtain our dimension formula. As for paramodular groups and Hecke type groups, our formula coincides with those conjectured in  and [7] Secondly, we give a geometric meaning of the dimensions of weight 3. We shall show that the dimensions of cusp forms of weight 3 is related with the geometry of principally polarized super singular abelian surfaces in several ways. It was known that certain arithmetic invariants of the locus of supersingular abelian surfaces in the moduli of principally polarized abelian surfaces over algebraically closed field of characteristic p are related with some class numbers of the compact real form of the split symplectic group Sp(2,R) of size four(due to Katsura, Oort and partly myself) These class numbers
Radiation free quantification of head malformations in craniosynostosis patients from 3D photography
Venue: Medical Imaging
Year: 2018

The evaluation of cranial malformations plays an essential role both in the early diagnosis and in the decision to perform surgical treatment for craniosynostosis. In clinical practice, both cranial shape and suture fusion are evaluated using CT images, which involve the use of harmful radiation on children. Three dimensional (3D) photography offers noninvasive, radiation free, and anesthetic free evaluation of craniofacial morphology. The aim of this study is to develop an automated framework to objectively quantify cranial malformations in patients with craniosynostosis from 3D photography. We propose a new method that automatically extracts the cranial shape by identifying a set of landmarks from a 3D photograph. Specifically, it registers the 3D photograph of a patient to a reference template in which the position of the landmarks is known. Then, the method finds the closest cranial shape to that of the patient from a normative statistical shape multi atlas built from 3D photographs of healthy cases, and uses it to quantify objectively cranial malformations. We calculated the cranial malformations on 17 craniosynostosis patients and we compared them with the malformations of the normative population used to build the multi atlas. The average malformations of the craniosynostosis cases were 2.68 0.75 mm, which is significantly higher (p<0.001) than the average malformations of 1.70 0.41 mm obtained from the normative cases. Our approach can support the quantitative assessment of surgical procedures for cranial vault reconstruction without exposing pediatric patients to harmful radiation.
Leishmaniose cutanee disseminee sur lymphoedeme deux cas
Year: 2008

Resume Introduction La dissemination d'une leishmaniose cutanee peut se faire sous differentes formes papules satellites, nodules sporotrichoides et papulonodules diffus (leishmaniose disseminee) Nous rapportons une forme particuliere de dissemination de leishmaniose cutanee chez deux malades ayant un erysipele survenant sur lymphoedeme. Observations Cas 1. Un homme age de 75 ans, diabetique consultait pour un erysipele de la jambe sur lymphoedeme sequellaire. La porte d'entree de l'erysipele etait une lesion de leishmaniose cutanee surinfectee. L'erysipele, traite par penicilline G, evoluait favorablement. Douze jours plus tard, apparaissaient une cinquantaine de lesions papulonodulaires, strictement localisees sur le placard d'erysipele. La recherche de corps de Leishman par polymerase chain reaction (PCR) sur les frottis dermiques de papulonodules etait positive. L'examen histologique des biopsies cutanees montrait un aspect de panniculite lobulaire. Cas 2. Une femme agee de 64 ans, diabetique, consultait pour un placard d'erysipele parseme de multiples lesions erythemateuses papuleuses infiltrees compliquant une lesion de leishmaniose cutanee. Ces lesions survenaient sur un lymphoedeme sequellaire du membre superieur droit. Les frottis dermiques avec etude en PCR sur les lesions nodulaires secondaires montraient la presence de leishmanies. L'examen histologique des biopsies cutanees montrait un aspect de panniculite.  La leishmaniose disseminee est definie par la presence de plus de dix lesions cutanees de leishmaniose d'aspect polymorphe sur au moins deux zones corporelles. Les deux cas comportaient certaines caracteristiques de leishmaniose disseminee. Cependant, ils etaient particuliers par la stricte localisation des lesions nodulaires sur le placard d'erysipele. Cet aspect pourrait evoquer une dissemination hemolymphatique favorisee par des facteurs locaux.
Developing Metacognition of Ethnocentrism with Lessing's "The Old Chief Mshlanga" and Voltaire's Candide
Year: 2013

The accurate perception of the Other can also be enhanced through the development of metacognition, the awareness, understanding, and control of one's own cognitive structures and processes and their consequences. "Mshlanga" is an excellent text for promoting metacognition of ethnocentrism because it models the development of such metacognition and also portrays the causes, operations, consequences, and processes for correcting ethnocentric cognition. Candide provides numerous episodes of ethnocentrism distorting perception of self and Other. With such episodes serving as exemplars of ethnocentric information processing, teachers can help their students learn to recognize the same cognitive processes underlying not only the actual historical realities that Voltaire is alluding to but also current beliefs and practices, including the students' own.
b lactoglobulin micro and nanostructures as bioactive compounds vehicle: In vitro studies.
Venue: Food research international
Year: 2020

b Lactoglobulin (b Lg) is known to be capable to bind hydrophilic and hydrophobic bioactive compounds. This research aimed to assess the in vitro performance of b Lg micro (diameter ranging from 200 to 300 nm) and nano (diameter 100 nm) structures associated to hydrophilic and hydrophobic model compounds on Caco 2 cells and under simulated gastrointestinal (GI) conditions. Riboflavin and quercetin were studied as hydrophilic and hydrophobic model compounds, respectively. Cytotoxicity experiment was conducted using in vitro cellular model based on human colon carcinoma Caco 2 cells. Moreover, the digestion process was simulated using the harmonized INFOGEST in vitro digestion model, where samples were taken at each phase of digestion process oral, gastric and intestinal and characterized in terms of particle size, polydispersity index (PDI) surface charge by dynamic light scattering (DLS) protein hydrolysis degree by 2,4,6 trinitrobenzene sulfonic acid (TNBSA) assay and native polyacrylamide gel electrophoresis; and bioactive compound concentration. Caco 2 cell viability was not affected up to 21 x 10 3 mg mL 1 of riboflavin and 16 x 10 3 mg mL 1 quercetin on b Lg micro and nanostructures. In the oral phase, b Lg structures' particle size, PDI and surface charge values were not changed comparing to the initial b Lg structures (i.e. before being subjected to in vitro GI digestion) During gastric digestion, b Lg structures were resistant to proteolytic enzymes and to acid environment of the stomach confirmed by TNBSA and native gel electrophoresis. In vitro digestion results indicated that b Lg micro and nanostructures protected both hydrophilic and hydrophobic compounds from gastric conditions and deliver them to target site (i.e. intestinal phase) In addition, b Lg structures were capable to enhance riboflavin and quercetin bioaccessibility and bioavailability potential compared to bioactive compounds in their free form. This study indicated that b Lg micro and nanostructures were capable to enhance hydrophilic and hydrophobic compounds bioavailability potential and they can be used as oral delivery systems.
A collocation method via the quasi affine biorthogonal systems for solving weakly singular type of Volterra Fredholm integral equations
Year: 2020

Tight framelet system is a recently developed tool in applied mathematics. Framelets, due to their nature, are widely used in the area of image manipulation, data compression, numerical analysis, engineering mathematical problems such as inverse problems, visco elasticity or creep problems, and many more. In this manuscript we provide a numerical solution of important weakly singular type of Volterra Fredholm integral equations WSVFIEs using the collocation type quasi affine biorthogonal method. We present a new computational method based on special B spline tight framelets and use it to introduce our numerical scheme. The method provides a robust solution for the given WSVFIE by using the resulting matrices based on these biorthogonal wavelet. We demonstrate the validity and accuracy of the proposed method by some numerical examples.
The moderating role of entrepreneurship education on the antecedents of entrepreneurial intention
Year: 2016

A considerable agreement exists about the importance of promoting entrepreneurship to stimulate economic development. In particular, recent research has paid considerable attention to the role of entrepreneurship education in explaining entrepreneurship intentions; also, numerous studies have found empirical evidence for subjective norms affecting the attitude toward entrepreneurial behavior and the perceived control over that behavior. However, cognitive models have not yet considered the moderating role of entrepreneurship education on these relationships. Drawing on the theory of planned behavior, we analyze how the interaction between entrepreneurship education and subjective norms shapes the perceptions and attitudes toward entrepreneurship. To this end, structural equation modeling is applied to data from a sample of 338 final year undergraduates using multi sample analysis. Results show that entrepreneurship education has a significant moderating role, mitigating the relationship between subjective norms and perceived behavioral control, and strengthening the relationship between subjective norms and entrepreneurial attitudes. Results also have relevant implications for women's entrepreneurship.
Intermolecular Interactions of Polymer/Surfactants Mixture in Aqueous Solution Investigated by Various Techniques
Year: 2013

The interaction between diblock copolymer with ionic surfactants in aqueous solution were studied employing surface tensiometery, electrical conductivity, steady state fluorescence spectroscopy and dynamic laser light scattering at 303 K. Surface tension measurements were used to determine critical micelle concentration (CMC) and, thereby, its free energy of micellization (DGm) free energy of adsorption (DGads) surface excess concentration (G) and minimum area per molecule (A) The negative values of (DGm) both in case of SDS and CTAB confirmed the spontaneity of the processes. Conductivity measurements were used to determine critical micelle concentration (CMC) critical aggregation concentration (CAC) polymer saturation point (PSP) degree of ionization (a) and counterion binding (b) Addition of polymers could effectively reduce the CMC value of surfactants and, thus increase the detergency. Dynamic light scattering experiments were performed to check the changes in physiochemical properties of the block copolymer micelles take place due to the interactions of diblock copolymer with ionic surfactants. The ratio of (I1/I3) indicates the polarity of the pyrene micro environment and confirms the detection of micelle as well as polymer surfactant interactions. Aggregation number (N) number of binding sites (n) and free energy of binding (DGb) for pure surfactants as well as for polymer surfactant mixed micellar systems were determined by fluorescence quenching method.
Dynamic Modeling of a Methanization Plant
Venue: Simul. Notes Eur.
Year: 2012

The chemical and physical modeling and transient simulation of a methanization plant with chemical reactors is useful for dimensioning, optimization, operation and analyzing of critical processes. The paper introduces the results of the development of a dynamic model for a commercial methanization process. The discussed models base on the free Modelica language and Dymola as user interface. The methanization plant consists of 3 adiabatic fixed bed reactors and steam generation units for heat recovery. Calculation results are shown for the dynamic behavior of the methanization plant at a load change.