nils-herrmann/clean_scirepeval huggingface dataset:
Pelvic retroperitoneal pleomorphic hyalinizing angiectatic tumor (PHAT) of soft tissue: a case report
Venue: BMC Medical Imaging
Year: 2016

BackgroundPleomorphic hyalinizing angiectatic tumor (PHAT) is a rare soft tissue tumor of low malignant potential, which most often arises in the lower extremities. Lesions occurred in other anatomic locations have been rarely reported. Moreover, their imaging features have not been well discussed. Here we report a case of PHAT arising primarily in the pelvic retroperitoneum. To our knowledge, this is the first radiological description for retroperitoneum PHAT.Case presentationA 26 year old female was referred to our hospital for evaluation of a pelvic mass incidentally noted in routine pre pregnancy ultrasonography examination. Magnetic resonance imaging (MRI) and computed tomography (CT) scan revealed an irregular mass with clear boundary in the pelvic retroperitoneum. Its signal intensity or density was inhomogeneous. On MRI images, it mainly showed isointense and slight hypointense on T1 weighted image and isointense and hyperintense on T2 weighted image. On contrast enhanced images, it showed marked but heterogenous enhancement. With the delay time increasing, the enhanced area in the lesion increased but the CT value decreased. Dilated vessels and hemorrhage were detected in the tumor. With patience and careful separation, it was completely excised with great amount of bleeding during operation. Pathological and immunohistochemistry analysis confirmed the diagnosis of PHAT of the soft parts. We found no evidence of recurrence 18 months after operation.ConclusionWe present an extremely rare case of PHAT arising primarily in the pelvic retroperitoneum. To our knowledge, this is the first radiological description for retroperitoneum PHAT. The provided information is useful for summarizing the characteristics of this kind of tumor. It should be included in the differential diagnosis of a well defined, inhomogenously enhanced hypervascular soft tissue mass in pelvic cavity.
Chio's like Method for Calculating the Rectangular (non square) Determinants: Computer Algorithm Interpretation and Comparison
Year: 2021

In this paper, we present an approach for the calculation of rectangular determinants, where in addition to the mathematical formula, we also provide a computer algorithm for their calculation. Firstly, we present a method similar to Sarrus method for calculating the rectangular determinant of the order 2 x 3. Secondly, we present an approach for calculating the rectangular determinants of order m xn by adding a row with all elements equal to one (1) in any row, as well as an application of Chio's rule for calculating the rectangular determinants. Thirdly, we find the time complexity and comparison of the computer execution time of calculation of the rectangular determinant based on the presented algorithms and comparing them with the algorithm based on the Laplace method.
A blockchain based PKI management framework
Venue: NOMS 2018 2018 IEEE/IFIP Network Operations and Management Symposium
Year: 2018

Public Key Infrastructure (PKI) is the cornerstone technology that facilitates secure information exchange over the Internet. However, PKI is exposed to risks due to potential failures of Certificate Authorities (CAs) that may be used to issue unauthorized certificates for end users. Many recent breaches show that if a CA is compromised, the security of the corresponding end users will be in risk. As an emerging solution, Blockchain technology potentially resolves the problems of traditional PKI systems in particular, elimination of single point of failure and rapid reaction to CAs shortcomings. Blockchain has the ability to store and manage digital certificates within a public and immutable ledger, resulting in a fully traceable history log. In this paper we designed and developed a blockchain based PKI management framework for issuing, validating and revoking X.509 certificates. Evaluation and experimental results confirm that the proposed framework provides more reliable and robust PKI systems with modest maintenance costs.
Angiotensin I converting enzyme (ACE) inhibitory tripeptides from rice protein hydrolysate: Purification and characterization
Year: 2013

In this study, angiotensin I converting enzyme (ACE) inhibitory tripeptides from rice protein hydrolysate were purified and their properties were further characterized. Val Asn Pro (VNP) and Val Trp Pro (VWP) were successfully purified from rice protein hydrolysate through multi step isolation and purification comprising of ultrafiltration and DA201 C macroporous adsorption resin, followed by a two step reverse phase high performance liquid chromatography (RP HPLC) The sequences of tripeptides were separately assayed by using automated protein/peptide sequencer. In addition, the stability of the tripeptides against ACE and simulated gastrointestinal proteases, ACE inhibitory kinetics, and their antihypertensive effects in vivo were evaluated. Our results showed that VNP (IC50 value of 6.4 mM) and VWP (IC50 value of 4.5 mM) were both competitive ACE inhibitors, and stability against ACE and gastrointestinal proteases of pepsin and chymotrypsin. Furthermore, single oral administration of the tripeptides VNP and VWP at 5 mg/kg body weight in spontaneously hypertensive rats (SHRs) significantly decreased the systolic blood pressure (SBP) of 29 and 38 mmHg (P
Visible Light Responsive Photocatalysts From TiO2 to Carbon Nitrides and Boron Carbon Nitride
Year: 2018

It can be said that energy depletion and environmental pollution on a global scale are the most serious and urgent issues facing mankind in recent times. It is, thus, vital to design novel energy production and conversion systems that utilize natural energy and allow sustainable development without environmental destruction or pollution. In line with these objectives, the decomposition of H2O into H2 and O2, as well as the related reactions using visible light responsive photocatalysts under sunlight irradiation, has been intensively investigated as one of the most promising environmentally benign energy production systems to address these issues. In the past half century, research on various photocatalytic systems using metal oxides has been carried out. However, to achieve higher efficiency in the production of H2, more innovative breakthroughs in the development of photocatalytic materials are strongly desired. To address such issues, graphitic carbon nitride (g C3N4) and hexagonal boron carbon nitride (BCN) nano materials have been investigated as promising visible light responsive photocatalytic materials. In this chapter, we have highlighted the development of such g C3N4 and hexagonal BCN photocatalytic nano materials, focusing on their design, construction and optimization, as well as their applications to environmentally benign solar energy conversion systems, for the decomposition of H2O, reduction and fixation of CO2, and organic redox reactions. Such visible light responsive photocatalytic materials are considered to be the most important research for the development of safe and clean energy production technologies for the 21st century and beyond.
Quel developpement professionnel des chefs d'etablissement Le cas de la Slovenie
Year: 2012

Cet article s'interesse a la formation des chefs d'etablissement a partir de l'eclairage fourni par les instances transnationales et de l'enseignement que l'on peut tirer des dilemmes relatifs au transfert de connaissances entre les systemes scolaires nationaux. En matiere de transfert de connaissances, l'article se penche particulierement sur le cas de l'Ecole nationale de formation a la direction d'etablissement en milieu educatif (NSLE) de Slovenie. Cet etablissement fonctionne a l'intersection du national et de l'international, de la theorie et de sa mise en oeuvre pratique, se confrontant ainsi aux limites de ses capacites d'intervention. La question se pose de savoir precisement dans quelle mesure les activites de l'etablissement contribuent a ameliorer les competences de direction et d'encadrement, les ecoles, le systeme scolaire slovene et, par la meme, les resultats des eleves.
Writing Oneself into Someone Else's Story Experiments with Identity and Speculative Life Writing in Twilight Fanfiction
Year: 2019

Fan fiction offers rich data to explore readers' understanding of gendered discourses informing the narrative construction of fictional and real life identities. This paper focuses on gender identity construction in self insertion fan fiction texts stories that involve avatars of fan writers based on Stephenie Meyer's Twilight novels. Self insertion fan fiction stories can be considered a form of life writing where authors play with their identity in a virtual context in texts that mix documentary elements and fiction; a combination that is here termed as speculative life writing. While earlier studies have discussed self insertion fan fiction as a potentially empowering form of resistance to conventional gendered discourses, or a space for (young) women to explore and play with their gendered and sexual identities, among fans themselves self insertion fan fiction stories especially stories involving 'Mary Sues' characters that are highly idealised versions of the author are often ridiculed. By drawing on concepts from narrative theory, discursive psychology and feminist discourse theory, the paper examines female protagonists in selected self insertion fanfics categorised as heterosexual romance and relates these representations to readers' comments about the stories. While selfinsertion fan fiction as speculative life writing allows for creatively experimenting with gendered identities, it is also conditioned by hegemonic gendered discourses and the norms of the particular online community.
Landscapes of ethical issues of emerging ICT applications in Europe
Year: 2009

A central problem of the attempt to bring to bear ethical ideas to technology, in particular information and communication technology is that it tends to arrive too late. It would clearly be desirable to have a better understanding of future technological developments in order to allow ethical considerations to influence design and implementations of technology. At the same time, the unavoidable contingency of future developments provides a fundamental limit to what we can know about the future. The current paper explores how this problem can be addressed. It provides a framework of technical developments that one can reasonably expect to materialise in the medium term future (10 to 15 years) and ethical issues that are currently expected to arise. This is done by analysing current European research funding documents with a view to exploring the trends, purposes, applications, artefacts, ethical issues, and governance structures that the European Commission foresees. The overall aim of the paper is to provide the conceptual basis of this framework.
Economic Impact of Micro Finance on Borrowers: Evidence from Punjab, Pakistan
Year: 2011

The purpose of this study is to investigate the economic impact of microfinance institutions on borrower households in particular the impacts of small amount of loans in a high inflationary economy like Pakistan. The study is based on primary data and comprises of a sample of two hundred households including borrowers of microfinance institutions and non borrowers who are eligible to be a client of MFIs. Binary logistic and least square regression is used to find the impact of microfinance on different economic indicators of the borrowers. Logistic regression results indicate positive and significant impact of microfinance on income of the borrower, while the least square regression presents somewhat different results about the impact of microfinance on assets of the borrower households. Independent sample T test was used to measure the significant difference between clients and non clients. We found that the economic position of the borrower households of microfinance institutions is better than the non borrowers.
Remote sensing and forest inventories in Nordic countries roadmap for the future
Year: 2018

The Nordic countries have long traditions in forest inventory and remote sensing (RS) In sample based national forest inventories (NFIs) utilization of aerial photographs started during the 1960s, satellite images during the 1980s, laser scanning during the 2000s, and photogrammetric point clouds during the 2010s. In forest management inventories (FMI) utilization of aerial photos started during the 1940s and laser scanning during the 2000s. However, so far, RS has mostly been used for map production and research rather than for estimation of regional parameters or inference on their accuracy. In recent years, the RS technology has been developing very fast. At the same time, the needs for information are constantly increasing. New technologies have created possibilities for cost efficient production of accurate, large area forest data sets, which also will change the way forest inventories are done in the future. In this study, we analyse the state of the art both in the NFIs and FMIs in the Nordic countries. We identify the benefits and drawbacks of different RS materials and data acquisition approaches with different user perspectives. Based on the analysis, we identify the needs for further development and emerging research questions. We also discuss alternatives for ownership of the data and cost sharing between different actors in the field.
Spectral Properties of Substituted Coumarins in Solution and Polymer Matrices
Venue: Molecules
Year: 2012

The absorption and fluorescence spectra of substituted coumarins (2 oxo 2H chromenes) were investigated in solvents and in polymer matrices. The substitutions involved were: (1) by groups with varying electron donating ability such as CH3, OCH3 and N(CH3)2, mainly, but not exclusively, in positions 7 and (2) by either CHO or 4 PhNHCONHN=CH in position 3. While the spectra of non substituted coumarin 3 carbaldehyde has absorptions at approximately 305 and 350 nm, substitution at position 7 leads to remarkable changes in the shape of the absorption spectrum and shifts the absorption to a longer wavelength. Similarly, the replacement of the formyl group with a semicarbazide group substantially influences the shape of the absorption spectrum, and coumarins which have only N(CH3)2 in position 7 experience small changes. These changes are associated with the increasing intramolecular charge transfer (ICT) character and increasing conjugation length of the chromophoric system, respectively, in the studied molecules. The fluorescence is almost negligible for derivatives which have H in this position. With increasing electron donating ability, and the possibility of a positive mesomeric +M) effect of the substituent in position 7 of the coumarin moiety, the fluorescence increases, and this increase is most intense when N(CH3)2 substitutes in this position, for both 3 substituted derivatives. Spectral measurements of the studied coumarins in polymer matrices revealed that the absorption and fluorescence maxima lay within the maxima for solvents, and that coumarins yield more intense fluorescence in polymer matrices than when they are in solution. The quantum yield of derivatives which have a dimethylamino group in position 7 in polymer matrices approaches 1, and the fluorescence lifetime is within the range of 0.5 4 ns. The high quantum yield of 7 dimethylamino derivatives qualifies them as laser dyes which have kF higher than knr in the given medium. This is caused by stiffening of the coumarin structure in polar polymer matrices, such as PMMA and PVC, due to higher micro viscosity than in solution and intermolecular dipole dipole interaction between chromophore (dopant) and matrix.
Genome wide association studies for complex traits: consensus, uncertainty and challenges
Venue: Nature Reviews Genetics
Year: 2008

The past year has witnessed substantial advances in understanding the genetic basis of many common phenotypes of biomedical importance. These advances have been the result of systematic, well powered, genome wide surveys exploring the relationships between common sequence variation and disease predisposition. This approach has revealed over 50 disease susceptibility loci and has provided insights into the allelic architecture of multifactorial traits. At the same time, much has been learned about the successful prosecution of association studies on such a scale. This Review highlights the knowledge gained, defines areas of emerging consensus, and describes the challenges that remain as researchers seek to obtain more complete descriptions of the susceptibility architecture of biomedical traits of interest and to translate the information gathered into improvements in clinical management.
Mediated Development: A Vygotskian Approach to Transforming Second Language Learner Abilities
Year: 2017

The authors point to systemic theoretical instruction (STI) which underscores the importance of abstract conceptual knowledge in schooling, and dynamic assessment (DA) in which mediators and learners function cooperatively, as examples of the theory practice relation envisioned by Vygotsky (1987) This article proposes an interactional framework to bridge STI and DA. Mediated development (MD) emphasizes mediator learner dialogic interaction in which the aim is not to assess emerging capabilities but rather to guide learner appropriation of concept based instructional materials as symbolic tools for thinking. The researchers situate MD in relation to the broader Vygotskian second language research tradition, while also acknowledging the contributions of Israeli researcher Reuven Feuerstein (Feuerstein, Feuerstein, Falik, 2010) Feuerstein's work to promote general cognitive abilities among learners with special needs closely parallels Vygotsky's research and was influential in developing this proposal of MD. The authors discuss principles of the framework and illustrate them through close analysis of excerpts of mediator learner interactions from an STI program to teach the English tense aspect system in a university level ESL academic writing program. Analysis reveals the value of mediator guidance in helping learners to recognize the relevance of instructional materials and to begin to use them as tools during communicative activity.
HUBUNGAN ANTARA ADVERSITY QUOTIENT DENGAN PRESTASI BELAJAR PADA MAHASISWA SEKOLAH TINGGI KEDINASAN X
Year: 2012

Proses belajar mahasiswa di STSN memang tidak selamanya berjalan lancar atau sesuai dengan rencana yang telah disusun, terkadang menemui hambatan, kesulitan, tantangan, yang tak jarang berujung pada kegagalan. Adversity quotient merupakan pengukuran kemampuan seseorang dalam merespon suatu tantangan dalam kehidupannya untuk mencapai keberhasilan, salah satunya yaitu pencapaian prestasi belajar. Permasalahannya lebih terletak pada seberapa mampu mahasiswa mengubah hambatan tersebut menjadi peluang yang menjanjikan. Dengan adanya daya juang, diharapkan mahasiswa dapat memperoleh prestasi belajar yang baik. Penelitian ini bertujuan menguji adakah hubungan antara Adversity quotient dengan prestasi belajar pada mahasiswa Sekolah Tinggi Kedinasan. Populasi dalam penelitian ini adalah seluruh mahasiswa STSN yang berada di Parung, Bogor yang berjumlah 70 orang. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif, dimana uji hipotesis dilakukan dengan teknik korelasi Product Moment dan diperoleh koefisiensi korelasi sebesar 0,507 dengan taraf signifikansi sebesar 0,000 (p <0,01) dengan demikian terlihat adanya hubungan yang sangat signifikan antara Adversity quotient dengan prestasi belajar pada mahasiswa Sekolah Tinggi Kedinasan. Kata Kunci Adversity quotient, Prestasi belajar
Recognition of Traffic Sign Based on Bag of Words and Artificial Neural Network
Venue: Symmetry
Year: 2017

The traffic sign recognition system is a support system that can be useful to give notification and warning to drivers. It may be effective for traffic conditions on the current road traffic system. A robust artificial intelligence based traffic sign recognition system can support the driver and significantly reduce driving risk and injury. It performs by recognizing and interpreting various traffic sign using vision based information. This study aims to recognize the well maintained, un maintained, standard, and non standard traffic signs using the Bag of Words and the Artificial Neural Network techniques. This research work employs a Bag of Words model on the Speeded Up Robust Features descriptors of the road traffic signs. A robust classifier Artificial Neural Network has been employed to recognize the traffic sign in its respective class. The proposed system has been trained and tested to determine the suitable neural network architecture. The experimental results showed high accuracy of classification of traffic signs including complex background images. The proposed traffic sign detection and recognition system obtained 99.00% classification accuracy with a 1.00% false positive rate. For real time implementation and deployment, this marginal false positive rate may increase reliability and stability of the proposed system.
Membrane cytoskeletal crosstalk mediated by myosin I regulates adhesion turnover during phagocytosis
Venue: Nature Communications
Year: 2019

Phagocytosis of invading pathogens or cellular debris requires a dramatic change in cell shape driven by actin polymerization. For antibody covered targets, phagocytosis is thought to proceed through the sequential engagement of Fc receptors on the phagocyte with antibodies on the target surface, leading to the extension and closure of the phagocytic cup around the target. We find that two actin dependent molecular motors, class 1 myosins myosin 1e and myosin 1f, are specifically localized to Fc receptor adhesions and required for efficient phagocytosis of antibody opsonized targets. Using primary macrophages lacking both myosin 1e and myosin 1f, we find that without the actin membrane linkage mediated by these myosins, the organization of individual adhesions is compromised, leading to excessive actin polymerization, slower adhesion turnover, and deficient phagocytic internalization. This work identifies a role for class 1 myosins in coordinated adhesion turnover during phagocytosis and supports a mechanism involving membrane cytoskeletal crosstalk for phagocytic cup closure.Phagocytosis of pathogens is thought to proceed through the sequential engagement of Fc receptors on the phagocyte with antibodies on the target surface. Here authors show that myosin 1e and myosin 1f link the actin cytoskeleton to the membrane and are required for efficient phagocytosis of antibody opsonized targets.
External fault identification experienced by 3 phase induction motor using PSVM
Venue: 2014 6th IEEE Power India International Conference (PIICON)
Year: 2014

Fault diagnosis and condition assessment (FDCA) of rotating machines becomes important due to the age of machine in service. Proper FDCA enhance the machine's operational life, efficiency and reducing catastrophic failure. This paper describes a realistic FDCA method for three phase induction motors (IMs) using readily available data. External faults experienced by IM are monitored by proximal support vector machine (PSVM) and compared its performance with standard support vector machine and artificial neural network which revealed that PSVM algorithm is quite faster in investigations leading to reduction in computational load. RMS value of 3 phase voltages and currents are utilized as input variable in PSVM model to identify six types of external faults experienced by IM and normal operating (NF) condition. Testing analysis of 160 samples has been carried out to represent the robustness of the investigated seven status conditions for wide changes in operating and loading condition perturbation.