nils-herrmann/clean_scirepeval huggingface dataset:
Facing the Challenges of Reconstructing Ancient Buildings
Year: 2018

Johnstone and Graff's contribution to what they term the "archaeology" of Greek rhetoric is original and significant. By describing the visual and acoustic characteristics of bouleuterion interiors, they help us to imagine the experiences of both speaker and audience in these spaces. Speeches before boulai could have been performative tours de force. Orators could have taken advantage of the settings to enhance their words' persuasive force, to present themselves in competition as confident, powerful men, and, perhaps, to generate particular aesthetic effects. Johnstone and Graff's approach reflects the contemporary trend of trying to situate ancient performance texts within the physical locations for which they were composed. Probably the most successful example of this is Bissera Pentcheva's work on Hagia Sophia. Pentcheva and her colleagues have demonstrated how the acoustic properties of Hagia Sophia, particularly its reverberation time, would have affected the experiences of hearing and performing hymns, psalms, and the sung sermons known as kontakia during the Justinianic liturgy of the sixth century CE. Hagia Sophia lends itself to this kind of research, since the complete building survives, as does a large and varied corpus of texts written about it or for performance within it. Johnstone and Graff's project faces the opposite situation. None of the dozens of known bouleuteria survives as anything approaching a complete building, and we have limited specific evidence of what went on within them. This essay considers Johnstone and Graff's analysis in light of these two challenges. All the bouleuteria Johnstone and Graff discuss are in more or less ruined condition. Sufficient remains of the foundations of the Old and New Bouleuteria in Athens survive for us to reconstruct the buildings' dimensions and floor plans, but we have limited evidence about the heights and materials of the walls and roof and the materials of interior surfaces. It is not even clear whether there were wooden benches for the bouleutai to sit on. Other buildings are better preserved. For the bouleuterion of Miletus, for instance, we know that the seats and walls were of marble and limestone, and we can reconstruct the exterior walls' height with reasonable accuracy. Even for the best preserved bouleuteria, fundamental architectural details, including the presence of windows and
Facial and Hand Scars Appearance after Autologous Nanofat Grafting in Patients with Post Burn Scars
Year: 2020

Management of unsightly post burn scars has changed tremendously in current era of cosmetic awareness. 5 12% of all worldwide injuries are burn injuries and approximately 11 million patients need hospital care. Multiple treatment methods for scar improvement including fat grafting are under investigation. Nano fat Grafting is newer modality of fat grafting for improving scar quality.  The aim of this study was to assess the outcome of facial and hand scars appearance after autologous Nanofat grafting in patients with post burn scars. Place and duration of study: The study was performed in Plastic Surgery Department of Shaikh Zayed hospital, Lahore Pakistan from October 2018 to September 2019.  30 patients with post burn scars of face and hands were included; age range was 18 to 43 years. Skin type 2 to 4 (Fitzpatrick skin type) Patients with skin graft, hypertrophic scars, contractures, or keloids were excluded. Scars were assessed by the patients and observer on a scale "POSAS" (Patient and Observer Scar Assessment Scale) the observer was a plastic surgeon. Scar was assessed before surgery using the POSAS scar scale. Fat was taken from the abdomen using 3mm cannulas with side holes of 1 2mm under tumescent conditions and transferred to 10 cc syringes with luer lock. Nano fat obtained after emulsification by passing 30 times from one syringe to another through luer lock. The follow up was on 7th day, at 3 months and at 6 months.  The mean POSAS score of observer decreased significantly from admission 35.8+ 4.0, at 3 months 31.3+ 3.8 and 6 months to 27.5+ 3.0, p value 0.05. The mean POSAS score of patients also significantly decreased, p value 0.05 over the same time period from admission at 42.4+ 5.2, to 3 month 37.3+ 4.0 and 6 month to 32.2+ 3.2.  Nano fat grafting results in improvement in scar appearance and is an effective approach towards the management post burn scar of face and hands.
Associations Between Police Work Stressors and Posttraumatic Stress Disorder Symptoms: Examining the Moderating Effects of Coping
Venue: Journal of police and criminal psychology
Year: 2018

The role of coping in the association between stress and posttraumatic stress disorder (PTSD) is not clear. We investigated the effects of active and passive coping strategies on the associations between police stress (administrative and organization pressure, physical and psychological threats, and lack of support) and PTSD symptoms in 342 police officers. Linear regression model was used in the analyses. The association between physical and psychological stress and PTSD symptoms was stronger in officers who used lower active coping (B 4.34, p 0.001) compared to those who utilized higher active coping (p interaction 0.027) (B 1.79, p 0.003) A similar result was found between lack of support and PTSD symptoms (p interaction 0.016) (lower active coping, B 5.70, p 0.001; higher active coping, B 3.33, p 0.001) but was not significantly different comparing the two groups regarding the association between administrative and organizational pressure and PTSD symptoms (p interaction 0.376) Associations of total stress, administrative and organizational pressure, and physical and psychological stressors with PTSD symptoms were significantly stronger in officers who utilized higher passive coping (p interaction 0.011, 0.030, and 0.023, respectively) In conclusion, low active or high passive coping methods may exacerbate the effect of work stress on PTSD symptoms.
Retinal Imaging and Image Analysis
Venue: IEEE Reviews in Biomedical Engineering
Year: 2010

Many important eye diseases as well as systemic diseases manifest themselves in the retina. While a number of other anatomical structures contribute to the process of vision, this review focuses on retinal imaging and image analysis. Following a brief overview of the most prevalent causes of blindness in the industrialized world that includes age related macular degeneration, diabetic retinopathy, and glaucoma, the review is devoted to retinal imaging and image analysis methods and their clinical implications. Methods for 2 D fundus imaging and techniques for 3 D optical coherence tomography (OCT) imaging are reviewed. Special attention is given to quantitative techniques for analysis of fundus photographs with a focus on clinically relevant assessment of retinal vasculature, identification of retinal lesions, assessment of optic nerve head (ONH) shape, building retinal atlases, and to automated methods for population screening for retinal diseases. A separate section is devoted to 3 D analysis of OCT images, describing methods for segmentation and analysis of retinal layers, retinal vasculature, and 2 D/3 D detection of symptomatic exudate associated derangements, as well as to OCT based analysis of ONH morphology and shape. Throughout the paper, aspects of image acquisition, image analysis, and clinical relevance are treated together considering their mutually interlinked relationships.
Plasmon enhanced light driven water oxidation by a dye sensitized photoanode
Venue: Proceedings of the National Academy of Sciences
Year: 2017

Dye sensitized photoelectrosynthesis cells (DSPECs) provide a basis for artificial photosynthesis and solar fuels production. By combining molecular chromophores and catalysts with high surface area, transparent semiconductor electrodes, a DSPEC provides the basis for light driven conversion of water to O2 and H2 or for reduction of CO2 to carbon based fuels. The incorporation of plasmonic cubic silver nanoparticles, with a strongly localized surface plasmon absorbance near 450 nm, to a DSPEC photoanode induces a great increase in the efficiency of water oxidation to O2 at a DSPEC photoanode. The improvement in performance by the molecular components in the photoanode highlights a remarkable advantage for the plasmonic effect in driving the 4e /4H+ oxidation of water to O2 in the photoanode. Dye sensitized photoelectrosynthesis cells (DSPECs) provide a flexible approach for solar water splitting based on the integration of molecular light absorption and catalysis on oxide electrodes. Recent advances in this area, including the use of core/shell oxide interfacial structures and surface stabilization by atomic layer deposition, have led to improved charge separation lifetimes and the ability to obtain substantially improved photocurrent densities. Here, we investigate the introduction of Ag nanoparticles into the core/shell structure and report that they greatly enhance light driven water oxidation at a DSPEC photoanode. Under 1 sun illumination, Ag nanoparticle electrodes achieved high photocurrent densities, surpassing 2 mA cm 2 with an incident photon to current efficiency of 31.8% under 450 nm illumination.
ATIM 39. PHASE 2 OPEN LABELED STUDY OF ADJUVANT TEMOZOLOMIDE PLUS TUMOR TREATING FIELDS PLUS PEMBROLIZUMAB IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (2 THE TOP)
Venue: Neuro Oncology
Year: 2019

Tumor treating Fields (TTFields) plus maintenance temozolomide is an approved standard treatment for newly diagnosed Glioblastoma (GBM) TTFields are alternating electric fields of low intensity and intermediate frequency delivered non invasively via transducer arrays to tumor region. Immune checkpoints have not been studied widely in newly diagnosed GBM patients. TTFields combined with temozolomide elicit anti mitotic effects on proliferative cancer cells and augment recruitment of immune effector cells specific for glioma cells to the tumor microenvironment where pembrolizumab further potentiates the immune reaction to achieve a synergistic therapeutic effect.  will determine if adding pembrolizumab to TTFields and maintenance temozolomide (triple combination) increases progression free survival (PFS) in patients with newly diagnosed GBM versus historical control (EF 14) This study will enroll patients (N=24) with pathologic diagnosis of newly diagnosed GBM WHO grade 4, 18 years after maximal surgery or biopsy followed by radiation therapy with adjuvant temozolomide (Stupp protocol) The primary endpoint is increases in PFS compared to historical control data (EF 14) Secondary endpoints include: toxicity and tolerability of the triple combination; overall survival and response rates versus historical data; augmentation of TTFields initiated glioma specific immune reaction by pembrolizumab. Exploratory endpoints include: metabolomics signature of immune activation by TTFields and TTFields plus pembrolizumab in serum and urine, and correlation of mutation burden in primary tumor samples with response to pembrolizumab plus TTFields. We assumed an accrual period of 12 months, an accrual rate of 2 patients per month, an additional 18 months of follow up, and proportional hazards. Per shape parameter estimate of k=0.88 with empirical 95% confidence interval (0.82, 0.95) obtained via simulation of historical control data, a sample size of 24 patients should detect an improvement in PFS of 6 to 8 months with 80% power and a 1 sided significance level of 0.05 (Wu and Xiong, 2014)
The Control of Seed Dormancy and Germination by Temperature, Light and Nitrate
Venue: The Botanical Review
Year: 2020

Seed dormancy and germination are two closely linked physiological traits that have great impacts on adaptation and survival of seed plants. Seed dormancy strengthen and germination potential are comprehensively influenced by a variety of internal factors and external environment cues. Environmental factors, such as water content, light condition, ambient temperature, and nitrogen availability, act as signal input to determine whether seeds keep in a dormant state or start to germinate. Light, temperature, and nitrogen availability are the most critical environmental factors that have profound impacts on seed dormancy and germination. However, the mechanisms underlying the regulation of seed dormancy and germination by environmental signals are still poorly understood. In this review, we summarize the current knowledge of signal transduction networks linking environmental stimulus to seed dormancy establishment, dormancy break and germination, underscoring the dominating roles of temperature, light, and nitric oxide. We review temperature, light, and nitric oxide signaling pathway separately as well as the integration of these signaling pathways with phytohormone abscisic acid (ABA) and gibberellins (GA) signaling pathway in the context of seed dormancy and germination.
Personalized recommender systems for product line configuration processes
Venue: Comput. Lang. Syst. Struct.
Year: 2018

Product lines are designed to support the reuse of features across multiple products. Features are product functional requirements that are important to stakeholders. In this context, feature models are used to establish a reuse platform and allow the configuration of multiple products through the interactive selection of a valid combination of features. Although there are many specialized configurator tools that aim to provide configuration support, they only assure that all dependencies from selected features are automatically satisfied. However, no support is provided to help decision makers focus on likely relevant configuration options. Consequently, since decision makers are often unsure about their needs, the configuration of large feature models becomes challenging. To improve the efficiency and quality of the product configuration process, we propose a new approach that provides users with a limited set of permitted, necessary and relevant choices. To this end, we adapt six state of the art recommender algorithms to the product line configuration context. We empirically demonstrate the usability of the implemented algorithms in different domain scenarios, based on two real world datasets of configurations. The results of our evaluation show that recommender algorithms, such as CF shrinkage, CF significance weighting, and BRISMF, when applied in the context of product line configuration can efficiently support decision makers in a most efficient selection of features.
Topography of connections between human prefrontal cortex and mediodorsal thalamus studied with diffusion tractography
Venue: NeuroImage
Year: 2010

Studies in monkeys show clear anatomical and functional distinctions among networks connecting with subregions within the prefrontal cortex. Three such networks are centered on lateral orbitofrontal cortex, medial frontal and cingulate cortex, and lateral prefrontal cortex and all have been identified with distinct cognitive roles. Although these areas differ in a number of their cortical connections, some of the first anatomical evidence for these networks came from tracer studies demonstrating their distinct patterns of connectivity with the mediodorsal (MD) nucleus of the thalamus. Here, we present evidence for a similar topography of MD thalamus prefrontal connections, using non invasive imaging and diffusion tractography (DWI DT) in human and macaque. DWI DT suggested that there was a high probability of interconnection between medial MD and lateral orbitofrontal cortex, between caudodorsal MD and medial frontal/cingulate cortex, and between lateral MD and lateral prefrontal cortex, in both species. Within the lateral prefrontal cortex a dorsolateral region (the principal sulcus in the macaque and middle frontal gyrus in the human) was found to have a high probability of interconnection with the MD region between the regions with a high probability of interconnection with other parts of the lateral prefrontal cortex and with the lateral orbitofrontal cortex. In addition to suggesting that the thalamic connectivity in the macaque is a good guide to human prefrontal cortex, and therefore that there are likely to be similarities in the cognitive roles played by the prefrontal areas in both species, the present results are also the first to provide insight into the topography of projections of an individual thalamic nucleus in the human brain.
Discussion of surface water and groundwater interaction in the Upper Crocodile River Basin, Johannesburg, South Africa: environmental isotope approach by Abiye et al.
Year: 2015

The water resources downstream of the West Rand Gold Field (a.k.a. the Western Basin) have been the subject of considerable interest and discussion in both the media (e.g. Bega, 2010; 2012a; 2012b; 2013; Groenewald, 2010; Jordan, 2015;  2015) and scientific literature. At the root hereof is concern for the impact of acid mine drainage (AMD) on the receiving water resources environment shared in part by the Cradle of Humankind World Heritage Site (COH WHS) South Africa. Attention that is so acutely focussed on a sensitive environment of outstanding universal value (OUV) such as the COH property requires scientific reporting that is rigorous and devoid of sentiment and emotion. The contribution by Abiye et al. (2015) to this discourse suffers from similar flaws as have plagued earlier scientific literature (e.g. Abiye, 2011; Abiye et al. 2011; Abiye, 2014; Durand, 2012; Durand and Peinke, 2010; Durand et al. 2010) on the topic. Perhaps the most understandable (and excusable) of these is sentiment and emotion. Scientific contributions to the topic, however, can and must attract keen scrutiny from peers. Such scrutiny will necessarily extend to previous similar publications by the author(s) Against this background, serious misgivings are raised regarding various elements of the material presented by Abiye et al. (2015) These are set out and argued in this discussion. In the subsection headed "Stream discharge within the study area" (p. 112) Abiye et al. (2015) report the seepage of " mine water into dolomites between P4 and P5 " at rates of 0.78 m3/s in the winter of 2011 and 0.92 m3/s in the summer of 2012. As illustrated in Figure 2 (p. 113) the seepage rates are based on streamflow measurements
Analysis on machine tool systems using spindle vibration monitoring for automatic tool changer
Year: 2015

Recently, the intelligent systems of technology have become one of the major items in the development of machine tools. One crucial technology is the machinery status monitoring function, which is required for abnormal warnings and the improvement of cutting efficiency. During processing, the mobility act of the spindle unit determines the most frequent and important part such as automatic tool changer. The vibration detection system includes the development of hardware and software, such as vibration meter, signal acquisition card, data processing platform, and machine control program. Meanwhile, based on the difference between the mechanical configuration and the desired characteristics, it is difficult for a vibration detection system to directly choose the commercially available kits. For this reason, it was also selected as an item for self development research, along with the exploration of a significant parametric study that is sufficient to represent the machine characteristics and states. However, we also launched the development of functional parts of the system simultaneously. Finally, we entered the conditions and the parameters generated from both the states and the characteristics into the developed system to verify its feasibility.
ARGOS8 variants generated by CRISPR Cas9 improve maize grain yield under field drought stress conditions
Venue: Plant biotechnology journal
Year: 2017

ARGOS8 is a negative regulator of ethylene responses. A previous study has shown that transgenic plants constitutively overexpressing ARGOS8 have reduced ethylene sensitivity and improved grain yield under drought stress conditions. To explore the targeted use of ARGOS8 native expression variation in drought tolerant breeding, a diverse set of over 400 maize inbreds was examined for ARGOS8 mRNA expression, but the expression levels in all lines were less than that created in the original ARGOS8 transgenic events. We then employed a CRISPR Cas enabled advanced breeding technology to generate novel variants of ARGOS8. The native maize GOS2 promoter, which confers a moderate level of constitutive expression, was inserted into the 5' untranslated region of the native ARGOS8 gene or was used to replace the native promoter of ARGOS8. Precise genomic DNA modification at the ARGOS8 locus was verified by PCR and sequencing. The ARGOS8 variants had elevated levels of ARGOS8 transcripts relative to the native allele and these transcripts were detectable in all the tissues tested, which was the expected results using the GOS2 promoter. A field study showed that compared to the WT, the ARGOS8 variants increased grain yield by five bushels per acre under flowering stress conditions and had no yield loss under well watered conditions. These results demonstrate the utility of the CRISPR Cas9 system in generating novel allelic variation for breeding drought tolerant crops.
DevOps for Serverless Applications
Year: 2018

Set up complete CI and CD pipelines for your serverless applications using DevOps principles Key Features Understand various services for designing serverless architecture Build CD pipelines using various cloud providers for your serverless applications Implement DevOps best practices when building serverless applications Book Description Serverless applications are becoming very popular among developers and are generating a buzz in the tech market. Many organizations struggle with the effective implementation of DevOps with serverless applications. DevOps for Serverless Applications takes you through different DevOps related scenarios to give you a solid foundation in serverless deployment. You will start by understanding the concepts of serverless architecture and development, and why they are important. Then, you will get to grips with the DevOps ideology and gain an understanding of how it fits into the Serverless Framework. You'll cover deployment framework building and deployment with CI and CD pipelines for serverless applications. You will also explore log management and issue reporting in the serverless environment. In the concluding chapters, you will learn important security tips and best practices for secure pipeline management. By the end of this book, you will be in a position to effectively build a complete CI and CD delivery pipeline with log management for serverless applications. What you will learn Explore serverless fundamentals and effectively combine them with DevOps Set up CI and CD with AWS Lambda and other popular Serverless service providers with the help of the Serverless Framework Perform monitoring and logging with serverless applications Set up a dynamic dashboard for different service providers Discover best practices for applying DevOps to serverless architecture Understand use cases for different serverless architectures Who this book is for DevOps for Serverless Applications is for DevOps engineers, architects, or anyone interested in understanding the DevOps ideology in the serverless world. You will learn to use DevOps with serverless and apply continuous integration, continuous delivery, testing, logging, and monitoring with serverless.