nils-herrmann/clean_scirepeval huggingface dataset:
Does geopolitical risk strengthen or depress oil prices and financial liquidity? Evidence from Saudi Arabia
Venue: Energy
Year: 2019

The present study assesses the causality of geopolitical risk (GPR) oil prices (OPs) and financial liquidity by means of wavelet analysis, which aims to investigate whether such relationships support the monetary equilibrium model in Saudi Arabia. Our findings indicate that OP and financial liquidity are related in the time domain when GPR is high. We detect both short and medium term correlations among OPs, financial liquidity and GPR in the frequency domain. Additionally, in the absence of GPR, we notice a mid term correlation between OPs and financial liquidity in the time and frequency domains. Our results support the assumed monetary equilibrium model, which, in turn, is an indication of the fact that OPs are dependent on GPR and that financial liquidity relies on the OP. Such conclusions suggest that the country would benefit from adopting a resource income diversification policy to reduce its impact on OP fluctuations. Additionally, the diversion of unnecessary government expenditures to the investment programs would also represent a beneficial shift in action.
A systematic review reporting quality of radiomics research in neuro oncology: toward clinical utility and quality improvement using high dimensional imaging features
Venue: BMC Cancer
Year: 2020

To evaluate radiomics analysis in neuro oncologic studies according to a radiomics quality score (RQS) system to find room for improvement in clinical use. Pubmed and Embase were searched up the terms radiomics or radiogenomics and gliomas or glioblastomas until February 2019. From 189 articles, 51 original research articles reporting the diagnostic, prognostic, or predictive utility were selected. The quality of the methodology was evaluated according to the RQS. The adherence rates for the six key domains were evaluated: image protocol and reproducibility, feature reduction and validation, biologic/clinical utility, performance index, a high level of evidence, and open science. Subgroup analyses for journal type (imaging vs. clinical) and biomarker (diagnostic vs. prognostic/predictive) were performed. The median RQS was 11 out of 36 and adherence rate was 37.1% Only 29.4% performed external validation. The adherence rate was high for reporting imaging protocol (100% feature reduction (94.1% and discrimination statistics (96.1% but low for conducting test retest analysis (2% prospective study (3.9% demonstrating potential clinical utility (2% and open science (5.9% None of the studies conducted a phantom study or cost effectiveness analysis. Prognostic/predictive studies received higher score than diagnostic studies in comparison to gold standard (P .001) use of calibration (P .02) and cut off analysis (P .001) The quality of reporting of radiomics studies in neuro oncology is currently insufficient. Validation is necessary using external dataset, and improvements need to be made to feature reproducibility, demonstrating clinical utility, pursuits of a higher level of evidence, and open science.
Lacking the Capsaicin Receptor Impaired Nociception and Pain Sensation in Mice
Year: 2007

www.sciencemag.org (this information is current as of January 3, 2007 The following resources related to this article are available online at http:/www.sciencemag.org/cgi/content/full/288/5464/306 version of this article at: including high resolution figures, can be found in the online Updated information and services, http:/www.sciencemag.org/cgi/content/full/288/5464/306#otherarticles 13 of which can be accessed for free: cites 35 articles This article 642 article(s) on the ISI Web of Science. cited by This article has been http:/www.sciencemag.org/cgi/content/full/288/5464/306#otherarticles 100 articles hosted by HighWire Press; see: cited by This article has been http:/www.sciencemag.org/cgi/collection/neuroscience Neuroscience subject collections This article appears in the following http:/www.sciencemag.org/help/about/permissions.dtl in whole or in part can be found at: this article permission to reproduce of this article or about obtaining reprints Information about obtaining
A novel multi objective evolutionary algorithm for recommendation systems
Venue: J. Parallel Distributed Comput.
Year: 2017

Nowadays, the recommendation algorithm has been used in lots of information systems and Internet applications. The recommendation algorithm can pick out the information that users are interested in. However, most traditional recommendation algorithms only consider the precision as the evaluation metric of the performance. Actually, the metrics of diversity and novelty are also very important for recommendation. Unfortunately, there is a conflict between precision and diversity in most cases. To balance these two metrics, some multi objective evolutionary algorithms are applied to the recommendation algorithm. In this paper, we firstly put forward a kind of topic diversity metric. Then, we propose a novel multi objective evolutionary algorithm for recommendation systems, called PMOEA. In PMOEA, we present a new probabilistic genetic operator. Through the extensive experiments, the results demonstrate that the combination of PMOEA and the recommendation algorithm can achieve a good balance between precision and diversity. A new topic diversity indicator is introduced, which can be used to measure various kinds of items in a recommendation list.A new probabilistic multi objective evolutionary algorithm (PMOEA) is presented, which is suitable for the recommendation systems.A new crossover operator is proposed to generate new solution, called the multi parent probability genetic operator.The experimental results show that PMOEA can achieve a good balance between precision and diversity.
Waterworks sludge filter sand permeable reactive barrier for removal of toxic lead ions from contaminated groundwater
Year: 2020

This study aims to use of inexpensive and available byproduct waterworks sludge resulted in huge quantities from the activities of water supply treatment system in the remediation of groundwater contaminated with lead ions as an application of sustainability principles. Results revealed that this material can be used effectively in the permeable reactive barrier technology. The best operational conditions for initial pH, contact time, and sorbent dosage in the batch tests were 5, 1 h, and 0.3 g/50 mL, respectively at agitation speed of 200 rpm and initial concentration of 50 mg/L to achieve the maximum removal efficiency (97 Langmuir isotherm model was introduced a fair description for sorption measurements with maximum capacity of 20.41 mg/g. Also, the precipitation/co precipitation processes were found the predominant mechanisms in the sorption process under consideration based on Fourier transform infrared spectroscopy (FT IR) and scanning electron microscopy (SEM) images in combination with final pH values. The developed model for continuous tests solved by COMSOL Multiphysics 3.5a to plot the contaminant transport under the effects of initial concentration, flowrate and bed depth. It is recognized that the model predictions can be simulated the experimental values with satisfactory concurrence where the coefficient of determination (R2) 0.983. The breakthrough point in the continuous transport was appeared earlier by decreasing the bed depth, and increasing both the initial concentration as well as the flow rate.
Neutrophil gelatinase associated lipocalin does not predict acute kidney injury in heart failure.
Venue: World journal of clinical cases
Year: 2020

Acute cardiorenal syndrome type 1 (CRS 1) is defined by a rapid cardiac dysfunction leading to acute kidney injury (AKI) Neutrophil gelatinase associated lipocalin (NGAL) is expressed on the surface of human neutrophils and epithelial cells, such as renal tubule cells, and its serum (sNGAL) and urinary have been used to predict AKI in different clinical settings.  To characterize CRS 1 in a cohort of patients with acute heart diseases, evaluating the potentiality of sNGAL as an early marker of CRS 1.  We performed a retrospective cohort, multi centre study. From January 2010 to December 2011, we recruited 202 adult patients admitted to the coronary intensive care unit (CICU) with a diagnosis of acute heart failure or acute coronary syndrome. We monitored the renal function to evaluate CRS 1 development and measured sNGAL levels within 24 h and after 72 h of CICU admission.  Overall, enrolled patients were hemodynamically stable with a mean arterial pressure of 92 (82 107) mmHg, 55/202 (27.2% of the patients developed CRS 1, but none of them required dialysis. Neither the NGAL delta value (AUC 0.40, 95%CI: 0.25 0.55) nor the NGAL peak (AUC 0.45, 95%CI: 0.36 0.54) or NGAL cut off 140 ng/mL) values were statistically significant between the two groups (CRS 1 vs no CRS1 patients) The area under the ROC curve for the prediction of CRS 1 was 0.40 (95%CI: 0.25 0.55) for the delta NGAL value and 0.45 (95%CI: 0.36 0.54) for the NGAL peak value. Finally, in multivariate analysis, the risk of developing CRS 1 was correlated with age 60 years, urea nitrogen at admission and 24 h urine output (AUC 0.83, SE 60.5% SP 93% while sNGAL was not significantly correlated.  In our population, sNGAL does not predict CRS 1, probably as a consequence of the mild renal injury and the low severity of heart disease. So, these data might suggest that patient selection should be taken into account when considering the utility of NGAL measurement as a biomarker of kidney damage.
Legal consciousness and legal culture in the context of legal education of future pharmacists
Year: 2017

One of the distinguishing features of man as a biological individual who is able to comprehend meaningfully the reality surrounding him and manage his actions is consciousness. Depending on the scientific theoretical approaches or applied needs, it is customary to apply a certain differentiation of definitions of the concept of consciousness, for example, everyday or political, individual or mass, the consciousness of school or student youth, and other. One of its varieties, perhaps the most important at the present stage of development of society and statehood, is the legal consciousness of man. The problem of the formation and functioning of the human sense of justice is one of the most popular and constantly developed in a number of scientific fields. The purpose of the work is to study the state of scientific knowledge of the legal consciousness and legal culture of student, future pharmacists in the context of legal education in the university.  According to a specific goal, the research was based on the analysis of international and national legislation, the database of scientific research developments of the National Library of Ukraine V.I. Vernadsky, the study of author's scientific works and professional publications on the formation of consciousness, legal consciousness and legal culture of youth, in particular, student. Methods of research bibliographic, linguistic, comparative analysis, content legal analysis.  The basic link of society is a person, as a biological individual, to which such mental entities as mind, consciousness and will are inherent. These qualities enable it to critically perceive the surrounding being, to realize and determine its place in the society, to program its perspective and direct its actions according to a specific goal. A specific form of consciousness is legal consciousness (legal awareness) the system of reflecting the legal reality in views, theories, concepts, feelings, people's ideas about law, its place and role in ensuring the freedom of the individual and other universal values. The level of assimilation by members of society of legal values (legal norms and principles, skills of lawful behavior, respect for law, etc. the degree of mastering them and their practical implementation is a legal culture. It is an integral part of the general culture of both the society as a whole and its member, demonstrating the level of rightness and legal activity of society.  During the research it was proved that the formation and improvement of the legal consciousness and legal culture is required by student youth, as the main bearer of the intellectual and physical potential of the nation. The issues of formation of legal consciousness and legal culture of students acquires special significance; these categories of youth should be formed not only by professionals of high qualification, but also by highly moral, highly cultured and law conscious citizens the real elite of a civilized, democratic society declared by the Constitution of Ukraine.
Addition of cellulose nanofibers extracted from rice straw to urea formaldehyde resin; effect on the adhesive characteristics and medium density fiberboard properties
Year: 2020

In this research cellulose nanofibers (CNF) were successfully extracted from rice straw through a chemomechanical method and then mixed with urea formaldehyde (UF) adhesive for the production of medium density fiberboard (MDF) The industrial grade liquid urea formaldehyde (UF) resin with formaldehyde: urea molar ratio of 1.15 was modified by adding 0.5, 1.5 and 2 wt of nanofibrillated cellulose (CNF) based on UF resin solids. The morphology, gel time, viscosity, and the non volatile solid content of the modified UF adhesive were investigated. Formaldehyde emission and some mechanical properties modulus of rupture (MOR) modulus of elasticity (MOE) and internal bond strength (IB) of the resulting MDF panels were measured. Solids content and viscosity of the UF adhesive decreased while gel time increased by mixing CNF with the resin. The formaldehyde emission of the panels made with UF containing CNF was lower than that of the panels made from neat UF while MOR, MOE and IB values increased by increasing the CNF content in the panels.
The FOCUUS Model Facilitating Occupational Performance on Campus: Uplifting Underrepresented Students
Year: 2021

The FOCUUS Model or Facilitating Occupational Performance on Campus: Uplifting Underrepresented Students, is a theoretically based, evidence centered model focused on ethnic minority (EM) students in higher education. The FOCUUS Model recognizes minority status as a determinant of health, where the experience of minority status stress (MSS) resulting from racism, stigmatization, marginalization, discrimination, microaggressions, and challenges to one's sense of belonging largely influence one's occupational performance, health, and overall well being. Historical and contemporary injustices within American culture have resulted in multigenerational occurrences of disparities for EMs. Racial injustice is deeply embedded and still ever present within practices and traditions in higher education institutions resulting in racialized experiences for EM students and contributing to further disparities in educational outcomes. The FOCUUS Model draws connections between historical and contemporary experiences of injustice by EM students in higher education on physical and mental health and various other outcomes. The FOCUUS Model illustrates the great influence and impact that these factors may have on EM students' overall well being, educational experiences, and academic performance. This model is intended to be utilized by program administrators and educators in higher education to support EM students including Black and/or African American, Indigenous and/or Native American, and other peoples of color including Latinx or Asian Pacific Islander Desi American. Occupational therapy (OT) programs can utilize this model to 1) gain knowledge about the EM student experience, 2) evaluate their current ideologies and practices, and 3) implement strategies suggested by the model to better support and uplift EM students.
Towards a Personalized Learning Experience Using Reinforcement Learning
Venue: Machine Learning Paradigms
Year: 2019

Cognitive computing has become one of the most promising fields, especially in education, where building adaptive learning systems that provide different learning paths and material based on learners' states and needs are developed. One of the most challenging issues in designing such systems is to correctly identify the factors that will influence the learning experience, especially when these factors highly differ from one learner to another. In addition, for one particular learner, the values of these factors change with time. In this paper, we present an approach that adapts to the most influential factors in learning in a way that varies from one learner to another and in different learning settings, including individual and collaborative learning. The approach utilizes reinforcement learning (RL) for building an intelligent environment that, not only does it provide a method for suggesting suitable learning materials, but it also provides a methodology for accounting for the continuously changing students' states and acceptance of the technology. We evaluate our system through simulations. The obtained results are promising and show the feasibility of the proposed approach. In addition, we propose a "rich" personalized learning system that relies on RL as its backend, while utilizing big data tools and learning analytics to continuously feed the system with new generated states.
Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review
Venue: Phytotherapy research PTR
Year: 2019

Milk thistle (Silybum marianum) is a medicinal plant from the Asteraceae family. Silymarin is the major constituent of milk thistle extract and is a mixture of some flavonolignans such as silybin, which is the most active component of silymarin. It is most commonly known for its hepatoprotective effect. Also, studies have shown other therapeutic effects such as anticancer, anti Alzheimer, anti Parkinson, and anti diabetic, so its safety is very important. It has no major toxicity in animals. Silymarin was mutagen in Salmonella typhimurium strains in the presence of metabolic enzymes. Silybin, silydianin, and silychristin were not cytotoxic and genotoxic at concentration of 100 mM. Silymarin is safe in humans at therapeutic doses and is well tolerated even at a high dose of 700 mg three times a day for 24 weeks. Some gastrointestinal discomforts occurred like nausea and diarrhea. One clinical trial showed silymarin is safe in pregnancy, and there were no anomalies. Consequently, caution should be exercised during pregnancy, and more studies are needed especially in humans. Silymarin has low drug interactions, and it does not have major effects on cytochromes P 450. Some studies demonstrated that the use of silymarin must be with caution when co administered with narrow therapeutic window drugs.
A randomized, open label, crossover study evaluating bioequivalence of two N acetylcysteine 2% oral solution formulations in healthy subjects
Venue: International journal of clinical pharmacology and therapeutics
Year: 2018

N acetylcysteine is a mucolytic agent used to treat bronchopulmonary diseases associated with airway mucus hypersecretion. The bioequivalence of a new oral N acetylcysteine 2% formulation was evaluated relative to an appropriate reference product.  This open label, randomized, crossover study assessed the bioequivalence of a new N acetylcysteine 2% oral solution compared to an approved reference N acetylcysteine 2% oral solution in healthy subjects in terms of pharmacokinetics, including area under the plasma concentration vs. time curve of N acetylcysteine plasma concentrations from time 0 to the last measurable sampling time point and the maximum postdose concentration. Bioequivalence was concluded if the 90% confidence intervals for the ratio of the geometric means of the two pharmacokinetic parameters with baseline correction were entirely within the range of 80 125% RESULTS 46 participants were randomized. The ratios of the geometric means for the test vs. reference treatment, with baseline correction, were 1.0961 (90% confidence interval: 1.0228, 1.1746) for area under the plasma concentration curve of test N acetylcysteine plasma concentrations and 1.0938 (90% confidence interval: 1.0142, 1.1796) for maximum postdose concentration; both were within the predefined range to demonstrate bioequivalence. Most treatment emergent adverse events were mild or moderate and not considered study drug related.  The new N acetylcysteine 2% oral solution was found to be bioequivalent to the marketed reference formulation. Treatments were generally safe and well tolerated.
Information extraction using neural language models for the case of online job listings analysis
Year: 2018

In this article we discuss the approach to information extraction (IE) using neural language models. We provide a detailed overview of modern IE methods: both supervised and unsupervised. The proposed method allows to achieve a high quality solution to the problem of analyzing the relevant labor market requirements without the need for a time consuming labelling procedure. In this experiment, professional standards act as a knowledge base of the labor domain. Comparing the descriptions of work actions and requirements from professional standards with the elements of job listings, we extract four entity types. The approach is based on the classification of vector representations of texts, generated using various neural language models: averaged word2vec, SIF weighted averaged word2vec, TF IDF weighted averaged word2vec, paragraph2vec. Experimentally, the best quality was shown by the averaged word2vec (CBOW) model.
Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair
Venue: Journal of orthopaedic research official publication of the Orthopaedic Research Society
Year: 2009

Meniscus injury is a frequently encountered clinical orthopedic issue and is epidemiologically correlated to osteoarthritis. The development of new treatments for meniscus injury is intimately related to the appropriateness of animal models for their investigation. The purpose of this study was to structurally compare human menisci to sheep and rabbit menisci to generate pertinent animal models for meniscus repair. Menisci were analyzed histologically, immunohistochemically, and by environmental scanning electron microscopy (ESEM) In all species, collagen I appeared throughout most menisci, but was absent from the inner portion of the tip in some samples. Collagen II was present throughout the inner main meniscal body, while collagen VI was found in pericellular and perivascular regions. The glycosaminoglycan rich inner portion of menisci was greater in area for rabbit and sheep compared to human. Cells were rounded in central regions and more fusiform at the surface, with rabbit being more cellular than sheep and human. Vascular penetration in rabbit was confined to the very outermost region (1% of meniscus length) while vessels penetrated deeper into sheep and human menisci (11 15% ESEM revealed a lamellar collagenous structure at the articulating surfaces of sheep and human menisci that was absent in rabbit. Taken together, these data suggest that the main structural features that will influence meniscus repair cellularity, vascularity, collagen structure are similar in sheep and human but significantly different in rabbit, motivating the development of ovine meniscus repair models.