nils-herrmann/clean_scirepeval huggingface dataset:
Urban traffic signal control using reinforcement learning agents
Year: 2010

This study presents a distributed multi agent based traffic signal control for optimising green timing in an urban arterial road network to reduce the total travel time and delay experienced by vehicles. The proposed multi agent architecture uses traffic data collected by sensors at each intersection, stored historical traffic patterns and data communicated from agents in adjacent intersections to compute green time for a phase. The parameters like weights, threshold values used in computing the green time is fine tuned by online reinforcement learning with an objective to reduce overall delay. PARAMICS software was used as a platform to simulate 29 signalised intersection at Central Business District of Singapore and test the performance of proposed multi agent traffic signal control for different traffic scenarios. The proposed multi agent reinforcement learning (RLA) signal control showed significant improvement in mean time delay and speed in comparison to other traffic control system like hierarchical multi agent system (HMS) cooperative ensemble (CE) and actuated control.
Fuzzy Assessment of Health Information System Users' Security Awareness
Venue: Journal of Medical Systems
Year: 2013

Health information systems (HIS) are a specific area of information systems (IS) where critical patient data is stored and quality health service is only realized with the correct use and efficient dissemination of this data to health workers. Therefore, a balance needs to be established between the levels of security and flow of information on HIS. Instead of implementing higher levels and further mechanisms of control to increase the security of HIS, it is preferable to deal with the arguably weakest link on HIS chain with respect to security: HIS users. In order to provide solutions and approaches for transforming users to the first line of defense in HIS but also to employ capable and appropriate candidates from the pool of newly graduated students, it is important to assess and evaluate the security awareness levels and characteristics of these existing and future users. This study aims to provide a new perspective to understand the phenomenon of security awareness of HIS users with the use of fuzzy analysis, and to assess the present situation of current and future HIS users of a leading medical and educational institution of Turkey, with respect to their security characteristics based on four different security scales. The results of the fuzzy analysis, the guide on how to implement this fuzzy analysis to any health institution and how to read and interpret these results, together with the possible implications of these results to the organization are provided.
Implementing social customer relationship management
Year: 2018

This paper aims to debate the technology driven transformation of customer relationship management (CRM) into social CRM, which entails a shift from a transactional and automational solution to a customer experience management philosophy, reflecting high levels of customer empowerment.,A literature review provides a critical analysis of the concept, tenets, aims and implementation approaches of social CRM. Arguments are summarised by developing a process based framework for implementing social CRM.,By adopting a value co creation approach that recognises the technology fostered customer empowerment, the social CRM highlights the need to immigrate from relationship management to relationship stewardship. In this vein, social CRM implementation should support and foster dialogue facilitation and customer engagement in co creating customer experiences. To achieve these, five approaches for implementing social CRM are proposed: collecting, analysing and interpreting customer insight; monitoring and improving the performance of CRM; developing holistic and seamless personalised customer experiences; gamifying CRM and loyalty programmes; and nurturing community relationship management.,The five approaches to social CRM implementation are identified and validated based on current industry practices, theoretical arguments and anecdotal evidence of professionals' perceptions about their outcomes. Future research is required to collect hard evidence showing the business and customer impacts of these approaches.,Social CRM immigrates relationship management from a transactional to a customer experience mindset that treats customers as co creators of value and demands the tourism and hospitality firms to exploit the affordances of information and communication technologies to collect and analyse customer data for better understanding the customer; develop customer touch points that do not only aim to sell but also primarily aim to enhance the customer interactions and experiences; consider and treat the customers and the customer communities as co creators, brand ambassadors and stewards of relations; and motivate and enable customer participation into value co creation processes for developing customer experiences and building relationships.,Research in social CRM is emerging, but it mainly focusses on defining its scope and identifying the functionality and adoption of social CRM technology. The paper contributes to the literature by proposing five specific approaches and a process framework for implementing social CRM. Various directions for future research are also provided.
Challenges and Opportunities for Design, Simulation, and Fabrication of Soft Robots
Year: 2014

This article describes new opportunities in soft robotics and some potential avenues to overcome challenges associated with the realization of these opportunities. New opportunities include new applications that exploit novel amorphous nonrigid dynamics, a new design space due to the elimination of traditional manufacturing constraints, more opportunities for modeling and mimicry of natural systems, and increased safety and mechanical compatibility with humans. Challenges include limited simulation and design automation tools, lack of soft actuation methods, and difficulty in manufacturing and component standardization. Both computational (e.g. evolutionary design tools) and mechanical (porous and jamming materials) approaches are proposed to alleviate these needs.
Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2
Venue: FEBS letters
Year: 2013

SUV420H1 and SUV420H2 are two highly homologous enzymes that methylate lysine 20 of histone H4 (H4K20) a mark that has been implicated in transcriptional regulation. In this study, we present the high resolution crystal structures of human SUV420H1 and SUV420H2 in complex with SAM, and report their substrate specificity. Both methyltransferases have a unique N terminal domain and Zn binding post SET domain, and prefer the monomethylated histone H4K20 as a substrate in vitro. No histone H4K20 trimethylation activity was detected by our radioactivity based assay for either enzyme, consistent with the presence of a conserved serine residue that forms a hydrogen bond with the target lysine side chain and limits the methylation level.
Discussion: Latent variable graphical model selection via convex optimization
Venue: ArXiv
Year: 2012

We want to congratulate the authors for a thought provoking and very interesting paper. Sparse modeling of the concentration matrix has enjoyed popularity in recent years. It has been framed as a computationally convenient convex 1constrained estimation problem in Yuan and Lin (2007) and can be applied readily to higher dimensional problems. The authors argue we think correctly that the sparsity of the concentration matrix is for many applications more plausible after the effects of a few latent variables have been removed. The most attractive point about their method is surely that it is formulated as a convex optimization problem. Latent variable fitting and sparse graphical modeling of the conditional distribution of the observed variables can then be obtained through a single fitting procedure. Practical aspects. The method deserves wide adoption, but this will only be realistic if software is made available, for example, as an R package. Not many users will go to the trouble of implementing the method on their own, so we will strongly urge the authors to do so. An imputation method. In the absence of readily available software, it is worth thinking whether the proposed fitting procedure can be approximated by methods involving known and well tested computational techniques. The concentration matrix of observed and hidden variables is K KO KOH K HO KH where we have deviated from the notation in the paper by omitting the asterisk. The proposed estimator Sn KO of KO was defined as
Rating obligacji korporacyjnych przedsiebiorstw gorniczych
Year: 2016

Streszczenie Artykul zostal poswiecony finansowaniu przedsiebiorstw branzy gorniczej poprzez wykorzystanie zrodla jakim jest emisja obligacji korporacyjnych. Koszt pozyskania takiego kapitalu jest zdeterminowany odpowiednim ratingiem obligacji nadawanym przez specjalistyczne agencje, ktore z kolei jest wynikiem ryzyka kredytowego przedsiebiorstwa bedacego emitentem. Obserwujac swiatowe tendencje w kontekscie finansowania inwestycji gorniczych mozna zauwazyc, iz odchodzi sie od tradycyjnych zrodel takich jak kredyty i pozyczki na rzecz tanszych zrodel takich jak obligacje korporacyjne. Celem artykulu jest zaprezentowanie determinant wplywajacych na szacowanie ratingu obligacji przedsiebiorstw gorniczych uwzgledniajacego specyfike ich funkcjonowania. Rating ten stanowi podstawe do okreslenia kosztow pozyskania dlugu w postaci obligacji korporacyjnych. W artykulu odnoszac sie do specyfiki branzy i jej ryzyk ustalono determinanty szacowania ratingu obligacji, ktory decyduje o ich oprocentowaniu i jednoczesnie stanowi koszt finansowania dzialalnosci emitenta. Zaprezentowane badania zostaly oparte na analizach najwiekszych firm ratingowych takich jak Moody's, Standards&Poor's oraz Fitch Ratings.
Semi automatic Quasi morphological Word Segmentation for Neural Machine Translation
Venue: DB&IS
Year: 2018

This paper proposes the Prefix Root Postfix Encoding (PRPE) algorithm, which performs close to morphological segmentation of words as part of text pre processing in machine translation. PRPE is a cross language algorithm requiring only minor tweaking to adapt it for any particular language, a property which makes it potentially useful for morphologically rich languages with no morphological analysers available. As a key part of the proposed algorithm we introduce the 'Root alignment' principle to extract potential sub words from a corpus, as well as a special technique for constructing words from potential sub words. We conducted experiments with two different neural machine translation systems, training them on parallel corpora for English Latvian and Latvian English translation. Evaluation of translation quality showed improvements in BLEU scores when the data were pre processed using the proposed algorithm, compared to a couple of baseline word segmentation algorithms. Although we were able to demonstrate improvements in both translation directions and for both NMT systems, they were relatively minor, and our experiments show that machine translation with inflected languages remains challenging, especially with translation direction towards a highly inflected language.
Una breve historia (arquitectonica) del siglo XX. Revision, celebracion y homenaje a 40 anos de <Breve historia de America> de Robert Crumb
Year: 2019

Los ultimos siglos han significado un desarrollo sin precedentes para la humanidad. Pero, a la vez, han supuesto un cambio en los paisajes del planeta, pasando de ser naturales a hechos por el hombre. Esta historia, contada por la elocuencia de un comic de Robert Crumb, deja en evidencia esta transformacion y nos ayuda a cuestionar nuestra propia intervencion en el planeta.
Miscelanea normativa de derecho sanitario: La autonomia del paciente, menores de edad y decisiones en sanidad y en la Interrupcion Voluntaria del Embarazo.
Year: 2016

En este articulo se exponen las novedades normativas relacionadas con la capacidad de decision del enfermo en caso de urgencia vital, la autonomia del menor de edad en el ambito sanitario, asi como la nueva regulacion de la Interrupcion Voluntaria del Embarazo en relacion con las menores de edad.
IMPLIKASI PERIKLANAN, PROMOSI PENJUALAN DAN HUBUNGAN MASYARAKAT TERHADAP MINAT BELI KONSUMEN(STUDI KASUS PADA KONSUMEN WALEU KAOS LAMPUNG)
Year: 2017

ABSTRAK IMPLIKASI PERIKLANAN, PROMOSI PENJUALAN DAN HUBUNGAN MASYARAKAT TERHADAP MINAT BELI KONSUMEN (STUDI KASUS PADA KONSUMEN WALEU KAOS LAMPUNG) Oleh NICK KURNIAWAN ROZALI Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh periklanan, promosi penjualan, dan hubungan masyarakat terhadap minat beli konsumen Waleu Kaos Lampung. Timbulnya minat, terdapat 3 unsur yaitu adanya sesuatu yang diminati, adanya penonjolan kontras antara suatu yang diminati dengan lingkungan, kemudian adanya harapan yang menyenangkan atau bermanfaat atas sesuatu yang tidak menyenangkan atau mengganggu. Penelitian ini menggunakan pendekatan regresi linear berganda yang dibantu oleh program SPSS versi 21. Hasil penelitian menunjukan bahwa secara parsial terdapat pengaruh yang signifikan antara periklanan dan hubungan masyarakat terhadap minat beli, tentunya bisa menjadi strategi yang harus dipertahankan bagi toko Waleu Kaos Lampung demi mempertahankan eksistensi produk Kaos Waleu.  Periklanan, Promosi Penjualan, Hubungan Masyarakat dan Minat beli ABSTRACT THE IMPLICATIONS OF ADVERTISING, SALES PROMOTION AND PUBLIC RELATIONS ON CONSUMER BUYING ( By NICK KURNIAWAN ROZALI This study aims to determine and analyze the influence of advertising, sales promotion, and public relations to consumer buying interest WaleuKaos Lampung. The emergence of interest, there are 3 elements of the existence of something of interest, the protrusion of contrast between an interest in the environment, then the hope of a fun or useful for something unpleasant or disturbing. This study uses multiple linear regression approach which is assisted by SPSS program version 21. The result of research shows that partially there is significant influence between advertising and publicity to buying interest, and there is no significant influence between sales promotion to buying interest. In this research, advertising and public relations factor has significant influence It certainly can be a strategic to keep an exsistencies product for Waleu and can be an improvement for Waleu Lampung store itself made in order to maintain the existence of WaleuKaos Lampung products.  Advertising, Sales Promotion, Public Relation and Buying Interest
Climate driven regime shift of a temperate marine ecosystem
Venue: Science
Year: 2016

No turning back? Ecosystems over time have endured much disturbance, yet they tend to remain intact, a characteristic we call resilience. Though many systems have been lost and destroyed, for systems that remain physically intact, there is debate as to whether changing temperatures will result in shifts or collapses. Wernburg et al. show that extreme warming of a temperate kelp forest off Australia resulted not only in its collapse, but also in a shift in community composition that brought about an increase in herbivorous tropical fishes that prevent the reestablishment of kelp. Thus, many systems may not be resilient to the rapid climate change that we face. Science, this issue p. 169 Rapid warming tropicalizes a temperate kelp forest. Ecosystem reconfigurations arising from climate driven changes in species distributions are expected to have profound ecological, social, and economic implications. Here we reveal a rapid climate driven regime shift of Australian temperate reef communities, which lost their defining kelp forests and became dominated by persistent seaweed turfs. After decades of ocean warming, extreme marine heat waves forced a 100 kilometer range contraction of extensive kelp forests and saw temperate species replaced by seaweeds, invertebrates, corals, and fishes characteristic of subtropical and tropical waters. This community wide tropicalization fundamentally altered key ecological processes, suppressing the recovery of kelp forests.
Impact of lithium alone and in combination with antidepressants on cytokine production in vitro
Venue: Journal of Neural Transmission
Year: 2014

Lithium is an important psychopharmacological agent for the treatment of unipolar as well as bipolar affective disorders. Lithium has a number of side effects such as hypothyroidism and aggravation of psoriasis. On the other hand, lithium has pro inflammatory effects, which appear beneficial in some disorders associated with immunological deficits, such as human immunodeficiency virus (HIV) infection and systemic lupus erythematosus (SLE) Therefore, immunological characteristics of lithium may be an important consideration in individualized therapeutic decisions. We measured the levels of the cytokines interleukin (IL) 1ss, IL 2, IL 4, IL 6, IL 22, IL 17 and tumour necrosis factor (TNF) a in the stimulated blood of thirty healthy subjects supplemented with lithium alone, the antidepressants citalopram, escitalopram or mirtazapine alone, the combination of each antidepressant with lithium, and a no drug control. These drugs were tested under three blood stimulant conditions: murine anti human CD3 monoclonal antibody OKT3 and the 5C3 monoclonal antibody (OKT3/5C3) phytohemagglutinin (PHA) and unstimulated blood. Lithium, alone and in combination with any of the tested antidepressants, led to a consistent increase of IL 1ss, IL 6 and TNF a levels in the unstimulated as well as the stimulated blood. In the OKT3/5C3 and PHA stimulated blood, IL 17 production was significantly enhanced by lithium. Lithium additionally increased IL 2 concentrations significantly in PHA stimulated blood. The data support the view that lithium has pro inflammatory properties. These immunological characteristics may contribute to side effects of lithium, but may also explain its beneficial effects in patients suffering from HIV infection or SLE.
Invagination appendiculaire chez une patiente atteinte de la maladie de Crohn
Year: 2020

Resume L'invagination de l'appendice est une entite rare pouvant etre responsable de douleurs abdominales chroniques et non expliquees. Elle est principalement associee a des remaniements inflammatoires ou a de l'endometriose. Chez une jeune femme de 23 ans atteinte de la maladie de Crohn, une invagination appendiculaire a ete diagnostiquee sur un scanner et lors d'une coloscopie realises pour des episodes aigus de douleurs abdominales. Ces episodes douloureux paroxystiques semblaient independants de la maladie de Crohn, mais plutot en rapport avec l'invagination. Une resection combinant a la fois une ligature par voie endoscopique et une typhlectomie par voie coelioscopique a ete realisee sans complication. Aucun argument en faveur d'une maladie de Crohn n'a ete retrouve a l'examen anatomopathologique de la piece operatoire.
Detection Method of Hg2+ Impurity Content in Marine Pollution Based on Intelligent Image Processing
Venue: Journal of Coastal Research
Year: 2019

Han, Y. and Li, Q. 2019. Detection method of Hg2+ impurity content in marine pollution based on intelligent image processing. In: Hoang, A.T. and Aqeel Ashraf, M. (eds. Research, Monitoring, and Engineering of Coastal, Port, and Marine Systems.  In order to improve the detection ability of Hg2+ impurity content in marine pollution, it is necessary to estimate the fractal dimension of Hg2+ impurity distribution image in marine pollution. A detection method of Hg2+ impurity content in marine pollution based on intelligent image processing is proposed. The super resolution fusion method is used to extract the significant area features of the collected Hg2+ impurity distribution image, and the fractal edge profile extraction model of Hg2+ impurity distribution image in marine pollution is constructed. The edge profile feature detection method is used for texture segmentation of Hg2+ impurity distribution image in marine pollution. Combined with weighted variance estimation method, the texture feature recognition of information fusion of Hg2+ impurity distribution image in marine pollution is carried out. The fractal dimension statistical analysis model of Hg2+ impurity distribution image in marine pollution is established, and the association regular pixel points of Hg2+ impurity distribution image in marine pollution are extracted. According to the color characteristic components of Hg2+ impurity distribution image in marine pollution, the multi level content detection is carried out. The simulation results show that the method has high accuracy and adaptability in the detection of Hg2+ impurity content in marine pollution, and improves the identification and detection ability of Hg2+ impurity content in marine pollution.
A Comparative Study upon the English Version for "Slow Slow Tune" from " the Principle of Three Beauties"
Year: 2013

It is not easy to translate poetry due to the differences between Chinese and English. Through an analysis of the English versions from Lin Yutang and Xu Yuanchong for"Slow Slow Tune"by Li Qingzhao,the paper probes the detailed application of" the Principle of Three Beauties"in translating Chinese classical poetry.
Building Microservices
Year: 2015

Distributed systems have become more fine grained in the past 10 years, shifting from code heavy monolithic applications to smaller, self contained microservices. But developing these systems brings its own set of headaches. With lots of examples and practical advice, this book takes a holistic view of the topics that system architects and administrators must consider when building, managing, and evolving microservice architectures. Microservice technologies are moving quickly. Author Sam Newman provides you with a firm grounding in the concepts while diving into current solutions for modeling, integrating, testing, deploying, and monitoring your own autonomous services. You'll follow a fictional company throughout the book to learn how building a microservice architecture affects a single domain.
Risks of ACE Inhibitor and ARB Usage in COVID 19: Evaluating the Evidence
Venue: Clinical pharmacology and therapeutics
Year: 2020

Concerns have been raised regarding the safety of angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) in patients with coronavirus disease of 2019 (COVID 19) based on the hypothesis that such medications may raise expression of ACE2, the receptor for severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) We conducted a literature review of studies (n 12) in experimental animals and human subjects (n 12) and evaluated the evidence regarding the impact of administration of ACEIs and ARBs on ACE2 expression. We prioritized studies that assessed ACE2 protein expression data, measured directly or inferred from ACE2 activity assays. The findings in animals are inconsistent with respect to an increase in ACE2 expression in response to treatment with ACEIs or ARBs. Control/sham animals show little to no effect in the plurality of studies. Those studies that report increases in ACE2 expression tend to involve acute injury models and/or higher doses of ACEIs or ARBs than are typically administered to patients. Data from human studies overwhelmingly imply that administration of ACEIs/ARBs does not increase ACE2 expression. Available evidence, in particular, data from human studies, does not support the hypothesis that ACEI/ARB use increases ACE2 expression and the risk of complications from COVID 19. We conclude that patients being treated with ACEIs and ARBs should continue their use for approved indications.