nils-herrmann/clean_scirepeval huggingface dataset:
A novel laser stripe center extraction method for pavement rut detection
Venue: Other Conferences
Year: 2018

The detection of road rutting is of great significance for reducing traffic accidents, verifying the degree of road damage, and improving the comfort of driving. The fast, real time and accurate stripe center extraction algorithm is the key to ensure the real time and stable operation of the system, which will directly affect the ultimate rut depth acquisition accuracy. For the existing laser stripe center extraction methods cannot meet the characteristics of good robustness, high precision, real time, strong anti noise ability at the same time. A signal correlation method, which always used in radar data processing, is proposed in this paper to extract the center of the laser stripes. The above algorithm can solve the problem of disconnection, but due to the use of a fixed reference column, the selection of the reference column is accidental, the relevant results will be affected by different reference columns. In order to solve this problem, this paper uses the method of multi column data correlation to take the maximum value. The algorithm is simple and practical, which can achieve the sub pixel level extraction accuracy, meet the real time requirements, has strong anti noise ability and repair ability for broken lines. The experimental results show that the algorithm is insensitive to high light intensity background, and the laser stripes center extraction accuracy can reach 0.15mm, which is far less than the 1mm inspection requirement for rutting road test specifications.
Optimal Charging of an Electric Vehicle Battery Pack: A Real Time Sensitivity Based MPC approach
Venue: ArXiv
Year: 2019

Lithium ion battery packs are usually composed of hundreds of cells arranged in series and parallel connections. The proper functioning of these complex devices requires suitable Battery Management Systems (BMSs) Advanced BMSs rely on mathematical models to assure safety and high performance. While many approaches have been proposed for the management of single cells, the control of multiple cells has been less investigated and usually relies on simplified models such as equivalent circuit models. This paper addresses the management of a battery pack in which each cell is explicitly modelled as the Single Particle Model with electrolyte and thermal dynamics. A nonlinear Model Predictive Control (MPC) is presented for optimally charging the battery pack while taking voltage and temperature limits on each cell into account. Since the computational cost of nonlinear MPC grows significantly with the complexity of the underlying model, a sensitivity based MPC (sMPC) is proposed, in which the model adopted is obtained by linearizing the dynamics along a nominal trajectory that is updated over time. The resulting sMPC optimizations are quadratic programs which can be solved in real time even for large battery packs (e.g. fully electric motorbike with 156 cells) while achieving the same performance of the nonlinear MPC.
Mesostructure and orientation control of lyotropic liquid crystals in a polysiloxane matrix
Venue: Polymer Journal
Year: 2019

AbstractAs a preparation method for organic inorganic or mesoporous inorganic materials via sol gel condensation of a metal alkoxide, the combination of lyotropic liquid crystals (LLCs) and sol gel chemistry is a versatile tool to fabricate various nanostructures. Despite previous investigations into such systems, no attempt has been made to utilize the dynamic switching functions of such nanostructures via the phase transition of LLCs in films. A polysiloxane containing an amine hydrochloride group and a vinyl group was recently synthesized. By controlling the relative humidity, we achieved the phase transition of LLCs and on demand UV curing of LLC phases in the polysiloxane film. We further developed vertically oriented organic inorganic nanochannels by using p p interactions between discotic molecules and the substrate surface or the spontaneous vertical alignment of LLC containing azobenzene units.A method to control on demand phase transition and alignment of organic inorganic hybrid containing lyotropic liquid crystals (LLCs) have been developed. By using polysiloxane containing hygroscopicity and photocrosslinking groups, the phase transition of the LLCs can be induced by changes in humidity. The phase transition behavior of the LLCs in polysiloxane can be suppressed by light irradiation. Further, the author proposed new methods for vertically aligning nanochannels by using surface interaction or the spontaneous vertical aligned nature, and photopatterning of chromonic dye aggregates.
COVID 19
Venue: International neurourology journal
Year: 2020

Samenvatting Verwekker: Coronavirus SARS CoV 2 Besmettingsweg: Mens op mens transmissie via directe druppelinfectie (hoesten en niezen) en aerosolen tijdens aerosolvormende handelingen Incubatietijd:2 14 dagen (gemiddeld 5 6 dagen) Besmettelijke periode:Nog niet volledig bekend. In ieder geval tijdens symptomatische fase waarna virus nog langer met PCR aantoonbaar kan zijn in de keel/feces Maatregelen: Meldingsplicht groep A; bronen contactonderzoek; isolatie en verdere maatregelen op indicatie Symptomen: Milde luchtwegklachten met koorts tot ernstige pneumonie en dyspnoe
MOUNTAIN TOURISM IN MACEDONIA: ASSESSMENT OF THE NATIONAL PARK "PELISTER"
Year: 2017

Macedonia, as a mountain country, has extraordinary natural preconditions and possibilities for developing mountain tourism. Although it possesses different types of accommodation facilities (mountain lodges and houses; children and youth vocation facilities; boarding houses; etc. Macedonia is facing many challenges. The article investigates the current level of mountain tourism development by elaborating the case of the National Park "Pelister" Bitola (Macedonia) The analysis is based on qualitative research method and incorporates: a) Survey and interviews with mountaineers and responsible persons for mountain tourism development; and b) Secondary data analysis, by reviewing literature. Generally, it was concluded that the evaluated national park has numerous weaknesses that need to be addressed and various profound limiting factors that prevent its tourism development. Yet, by segmented and a tailor made promotion, the National Park "Pelister" may gain many economic benefits thus overcoming the current scarce tourism valorization and at the same time, may boost mountain tourism development in Macedonia.
Wuji: Automatic Online Combat Game Testing Using Evolutionary Deep Reinforcement Learning
Venue: 2019 34th IEEE/ACM International Conference on Automated Software Engineering (ASE)
Year: 2019

Game testing has been long recognized as a notoriously challenging task, which mainly relies on manual playing and scripting based testing in game industry. Even until recently, automated game testing still remains to be largely untouched niche. A key challenge is that game testing often requires to play the game as a sequential decision process. A bug may only be triggered until completing certain difficult intermediate tasks, which requires a certain level of intelligence. The recent success of deep reinforcement learning (DRL) sheds light on advancing automated game testing, without human competitive intelligent support. However, the existing DRLs mostly focus on winning the game rather than game testing. To bridge the gap, in this paper, we first perform an in depth analysis of 1349 real bugs from four real world commercial game products. Based on this, we propose four oracles to support automated game testing, and further propose Wuji, an on the fly game testing framework, which leverages evolutionary algorithms, DRL and multi objective optimization to perform automatic game testing. Wuji balances between winning the game and exploring the space of the game. Winning the game allows the agent to make progress in the game, while space exploration increases the possibility of discovering bugs. We conduct a large scale evaluation on a simple game and two popular commercial games. The results demonstrate the effectiveness of Wuji in exploring space and detecting bugs. Moreover, Wuji found 3 previously unknown bugs, which have been confirmed by the developers, in the commercial games.
C. elegans interprets bacterial non coding RNAs to learn pathogenic avoidance.
Venue: Nature
Year: 2020

Caenorhabditis elegans must distinguish pathogens from nutritious food sources among the many bacteria to which it is exposed in its environment1. Here we show that a single exposure to purified small RNAs isolated from pathogenic Pseudomonas aeruginosa (PA14) is sufficient to induce pathogen avoidance in the treated worms and in four subsequent generations of progeny. The RNA interference (RNAi) and PIWI interacting RNA (piRNA) pathways, the germline and the ASI neuron are all required for avoidance behaviour induced by bacterial small RNAs, and for the transgenerational inheritance of this behaviour. A single P. aeruginosa non coding RNA, P11, is both necessary and sufficient to convey learned avoidance of PA14, and its C. elegans target, maco 1, is required for avoidance. Our results suggest that this non coding RNA dependent mechanism evolved to survey the microbial environment of the worm, use this information to make appropriate behavioural decisions and pass this information on to its progeny.
The Effect of Self efficacy on Intermediate EFL Learner's Reading Comprehension Improvement: Evidence from Iranian English Learners
Year: 2019

This study was an attempt to examine the effect of self efficacy on Iranian EFL learners' reading comprehension. Reading comprehension plays a significant role in educational success. In spite of its importance, students still have difficulties in understanding texts. One solution to the problem of poor reading comprehension is the learning of reading strategies. The current study examined the effect of summarizing strategy on reading comprehension of Iranian intermediate EFL learners. Pretest posttest design was employed to scrutinize the possible improvements of two classes of intermediate English learners (one experimental and one control group) as reading comprehension was concerned. Two groups were exposed to the same reading test as the pre and the post test, however, only the experimental groups received the special treatment regarding to promote their self efficacy. After the application of the study's treatment, data analysis process initiated which indicated that experimental groups who received treatment had a better performance than the control group on the final reading test. In addition, the findings suggested that self efficacy were same in male and female participants. The findings of the study indicated that summarizing strategy has a significant effect on learners' reading comprehension. Generally, the findings imply that self efficacy can positively affect the reading comprehension ability of the intermediate EFL learners.
Examining Sources and Mechanisms of Reading Comprehension Difficulties: Comparing English Learners and Non English Learners within the Simple View of Reading.
Venue: Journal of educational psychology
Year: 2019

In the present study, we compared the extent to which linguistic comprehension (vocabulary and listening comprehension) and word reading explain reading comprehension differentially for English learners (ELs) and non ELs with reading difficulties, and we investigated whether different mechanisms of reading comprehension failure exist for each group. Using the simple view of reading as our framework, we tested a model in which vocabulary exerts a direct effect on reading comprehension and indirect effects through listening comprehension and word reading. Results from a multigroup structural equation model with a sample of 446 struggling fourth grade readers (n 229 for ELs; n 211 for non ELs) demonstrated both similarities and differences in the sources and mechanisms of reading comprehension difficulties for ELs and non ELs with reading problems. Word reading was an important source of reading comprehension difficulty for both groups. For non ELs, the effect of word reading was larger than the effects of linguistic comprehension (vocabulary and listening comprehension combined) however, for ELs, the effects of linguistic comprehension were greater than the effect of word reading. Vocabulary had indirect effects via both listening comprehension and word reading for ELs, but it demonstrated a direct effect on reading comprehension for non ELs. These results suggest that developing a range of linguistic comprehension skills (e.g. word level and sentence level language skills) may be important for ELs with reading comprehension difficulties in the upper elementary grades.
Health Care Provider Barriers to HIV Pre Exposure Prophylaxis in the United States: A Systematic Review.
Venue: AIDS patient care and STDs
Year: 2020

Increasing prescription of pre exposure prophylaxis (PrEP) is imperative to ending the HIV epidemic in the United States. The objective of this review was to identify health care provider barriers to PrEP implementation. A systematic review was conducted in February 2019 using PubMed to identify barriers to PrEP prescribing practices in the United States. Targeted search terms surrounding PrEP and providers resulted in 222 original studies, 28 of which were ultimately included in our review, with data collected between 2011 and 2018. Six themes were identified across reviewed studies: (i) a lack of PrEP knowledge, (ii) the presence of the Purview Paradox, which refers to discordance in beliefs between HIV specialists and primary care providers on who should prescribe PrEP, (iii) concerns about PrEP costs, (iv) concerns about behavioral and health consequences, (v) interpersonal stigma, and (vi) concerns about patient adherence. A majority of providers were lacking knowledge regarding PrEP, resulting in discomfort in prescribing PrEP, or limited awareness and understanding of PrEP clinical guidelines. Discrepant opinions were identified regarding whether PrEP was best managed within primary care or specialty clinics. Other barriers included concerns about cost, patient adherence, and follow up maintenance care. Finally, concerns about risk compensation and discomfort discussing sexual activities with patients who would benefit most from PrEP were apparent. Additional work is needed to prepare providers to prescribe and manage patients on PrEP, optimize PrEP delivery, and reduce provider bias. Future research is needed to identify providers' attitudes and beliefs regarding innovations in PrEP dosing, task shifting, and novel strategies for PrEP care.
Detecting overlapping protein complexes in protein protein interaction networks
Venue: Nature Methods
Year: 2012

We introduce clustering with overlapping neighborhood expansion (ClusterONE) a method for detecting potentially overlapping protein complexes from protein protein interaction data. ClusterONE derived complexes for several yeast data sets showed better correspondence with reference complexes in the Munich Information Center for Protein Sequence (MIPS) catalog and complexes derived from the Saccharomyces Genome Database (SGD) than the results of seven popular methods. The results also showed a high extent of functional homogeneity.
Learning Media in Pandemic: Autoplay Media Studio Added Stretching Motion to Evaluation Digestive System Subject
Year: 2020

Development of learning media with Autoplay Media Studio program accompanied by instructions for warm up body in answering evaluations is based on the fact that during the Covid 19 pandemic this limited all student activity and learning. The decrease in the activity of student will disrupt the body's metabolism because just live at home or boarding house so that it is difficult to learn and even understand material when online lecturing. The addition of exercise warm up instruction to this learning media aims to make students not only learn to understand material, but also practice their bodies during pandemic period they can still maintain body fitness. Development method uses five stages called the ADDIE model. Products in the form of media containing digestive system material with various types of data in the form of writing, images and videos combined in one compact disk. Two validators conducted an assessment of the correctness of the material content and media appearance. The results of media validation get a 98.61% and material validation get 98.53% score with very valid criteria and not revised. Results of product trials on 25 students showed 96% of students rated the appearance of the media as attractive and 4% rated the display in medium criteria. The use of media accompanied by warm up movements, including the criteria for helping students learn independently in pandemic, was expressed by 68% of students, 24% of students stated that media was included in the medium criteria and 8% of students stated that the media could not help.
Capsaicin induced metabolic and cardiovascular autonomic improvement in an animal model of the metabolic syndrome
Venue: British Journal of Nutrition
Year: 2013

The metabolic syndrome (MetS) is associated with an increased risk of cardiac mortality, as it is characterised by the clustering of multiple cardiovascular risk factors. Studies have shown that capsaicin (red pepper) may be useful as a nutraceutical, ameliorating metabolic profile and cardiovascular function. The aim of the present study was to investigate the cardiovascular and metabolic effects of orally administered capsaicin in rats with the MetS. Neonate spontaneously hypertensive rats were injected with monosodium glutamate and subjected to one of the following three treatments by oral administration for 14 d, between 27 and 30 weeks: low dose capsaicin (CAP05, n 18, synthetic capsaicin powder diluted in a vehicle (10 ethyl alcohol) plus 0*5 mg/kg body weight (BW) of capsaicin) high dose capsaicin (CAP1, n 19, synthetic capsaicin powder diluted in a vehicle (10 ethyl alcohol) plus 1 mg/kg BW of capsaicin) control (C, n 18, vehicle) Lee's index, lipid/metabolic profile, and cardiovascular parameters with the rats being conscious, including arterial pressure (AP) and heart rate (HR) variability, as well as aortic wall thickness (haematoxylin and eosin staining) and CD68 (cluster of differentiation 68) antibody levels (monocyte/macrophage immunostaining) were evaluated. Weight, Lee's index, and lipid and metabolic parameters, as well as AP and HR and aortic wall thickness, were similar between the groups. Capsaicin determined HR variability improvement (16*0 (sem 9*0) 31*0 (sem 28*2) and 31*3 (sem 19*0) ms2 for the C, CAP05 and CAP1 groups, respectively, P= 0*003) increased vascular sympathetic drive (low frequency component of systolic AP variability: 3*3 (sem 2*8) 8*2 (sem 7*7) and 12*1 (sem 8*8) mmHg2 for the C, CAP05 and CAP1 groups, respectively, P< 0*001) and increased a index (spontaneous baroreflex sensitivity) The present data show that capsaicin did not improve lipid and glucose abnormalities in rats with the MetS. However, beneficial cardiovascular effects were observed with this nutraceutical.
MicroRNA 30a regulates chondrogenic differentiation of human bone marrow derived mesenchymal stem cells through targeting Sox9
Venue: Experimental and therapeutic medicine
Year: 2019

Cartilage injury is difficult to repair since the cartilage tissue lacks self restoration ability. Improved formation of chondrocytes differentiated from the mesenchymal stem cells (MSC) by genetic regulation is a potentially promising therapeutic option. SOX9 is a critical transcription factor for mesenchymal condensation prior to chondrogenesis. Previous studies demonstrated that several microRNAs (miRNAs or miRs) play a critical role in the chondrogenic differentiation of MSCs. However, the interactional relations between miR 30a and SOX9 during chondrogenic differentiation of MSCs need to be further elucidated. In the present study, human bone marrow derived mesenchymal stem cells have been isolated and induced into chondrogenic differentiation to imitate the cartilage formation in vitro. Additionally, the expression levels of several miRNAs that were reported to interact with the SOX9 3'untranslated region (UTR) were examined by using reverse transcription quantitative PCR. The interactional relations between candidate miRNAs and SOX9 were verified with the transfection of a miRNA mimic or inhibitor and a luciferase reporter gene assay. The results indicate that miR 30a and miR 195 were consistently increased during MSC chondrogenic differentiation. Additionally, the binding of miR 30a to the SOX9 3UTR was verified. Then, the authors upregulated the expression of miR 30a and found that MSC chondrogenic differentiation was inhibited. Taken together, the results of the present study demonstrate that miR 30a has a negative regulatory effect on MSC chondrogenic differentiation by targeting SOX9. Advances in epigenetic regulating methods will likely be the future of systemic treatment of cartilage injury.
How do Technical Debt Payment Practices Relate to the Effects of the Presence of Debt Items in Software Projects?
Venue: 2021 IEEE International Conference on Software Analysis, Evolution and Reengineering (SANER)
Year: 2021

Knowing the effects of technical debt (TD) can support software development teams in the prioritization of TD items to pay off. However, little is known about the relations between the effects of TD and TD payment practices. Having this knowledge can provide valuable information for decision making about which payment practice can be applied given the presence of specific effects of TD.  To investigate, from the point of view of software practitioners, (i) which TD payment practices have been used when certain effects of the presence of debt are felt in software projects and (ii) the reasons for not paying debt items despite the effects they are causing to the project.  We analyze quantitatively and qualitatively data collected from a survey with 432 practitioners across four countries.  Among the identified relations, the practice "code refactoring" is commonly used to pay debt items off when the effects "delivery delay" and "rework" are felt in software projects. On the other hand, when practitioners face the TD effects "low external quality" and "delivery delay" ,they commonly justify the non payment of the debt items indicating the need of "focusing on short term goals"  We organize the relationship between TD effects, and payment practices and reasons for not eliminating debt items. All this information is structured in an alluvial diagram, which can facilitate the visualization of the identified relations.