nils-herrmann/clean_scirepeval huggingface dataset:
Computational and Experimental Evidence of Emergent Equilibrium Isotope Effects in Anion Receptor Complexes
Venue: Journal of the American Chemical Society
Year: 2017

The measurement of a deuterium equilibrium isotope effect (EIE) for the aryl CH**Cl interaction of anion receptor 1H/1D is reported. Computations corroborate the results of solution measurements for a small, normal EIE in the full complex (KaH/KaD 1.019 0.010) Interestingly, isotope effects involving fragments of the anion receptor (urea, aryl ring, etc. are predicted to produce an inverse effect. This points to an unusual and subtle structural organization effect of the anion receptor complex that changes the nature of the combined interactions to a normal isotope effect. The reversal of EIE values suggests that overall architecture of the anion receptor can dramatically impact the nature of bonding in these complexes.
Multilingual Multi Domain Adaptation Approaches for Neural Machine Translation
Venue: ArXiv
Year: 2019

In this paper, we propose two novel methods for domain adaptation for the attention only neural machine translation (NMT) model, i.e. the Transformer. Our methods focus on training a single translation model for multiple domains by either learning domain specialized hidden state representations or predictor biases for each domain. We combine our methods with a previously proposed black box method called mixed fine tuning, which is known to be highly effective for domain adaptation. In addition, we incorporate multilingualism into the domain adaptation framework. Experiments show that multilingual multi domain adaptation can significantly improve both resource poor in domain and resource rich out of domain translations, and the combination of our methods with mixed fine tuning achieves the best performance.
Functional Carbon Quantum Dots as Medical Countermeasures to Human Coronavirus
Venue: ACS applied materials interfaces
Year: 2019

Therapeutic options for the highly pathogenic human coronavirus (HCoV) infections are urgently needed. Anticoronavirus therapy is however challenging, as coronaviruses are biologically diverse and rapidly mutating. In this work, the antiviral activity of seven different carbon quantum dots (CQDs) for the treatment of human coronavirus HCoV 229E infections was investigated. The first generation of antiviral CQDs was derived from hydrothermal carbonization of ethylenediamine/citric acid as carbon precursors and postmodified with boronic acid ligands. These nanostructures showed a concentration dependent virus inactivation with an estimated EC50 of 52 8 mg mL 1. CQDs derived from 4 aminophenylboronic acid without any further modification resulted in the second generation of anti HCoV nanomaterials with an EC50 lowered to 5.2 0.7 mg mL 1. The underlying mechanism of action of these CQDs was revealed to be inhibition of HCoV 229E entry that could be due to interaction of the functional groups of the CQDs with HCoV 229E entry receptors; surprisingly, an equally large inhibition activity was observed at the viral replication step.
Dynamic expression profiles of virus responsive and putative antimicrobial peptide encoding transcripts during Atlantic cod (Gadus morhua) embryonic and early larval development.
Venue: Gene
Year: 2012

Early life stage mortality is one of the problems faced by Atlantic cod aquaculture. However, our understanding of immunity in early life stage fish is still incomplete, and the information available is restricted to a few species. In the present work we investigated the expression of immune relevant transcripts in Atlantic cod during early development. The transcripts subjected to QPCR analysis in the present study were previously identified as putative anti viral or anti bacterial genes in Atlantic cod using suppression subtractive hybridization (SSH) libraries, QPCR, and/or microarrays. Of the 11 genes involved in this study, only atf3, cxc chemokine and gaduscidin 1 were not detected at the transcript level in all developmental stages investigated from unfertilized egg to early larval stage. Adam22, hamp, il8, irf1, irf7, lgp2, sacsin, and stat1 transcripts were detected in unfertilized egg and 7h post fertilization ~2 cell stage) embryos, showing maternal contribution of these immune relevant transcripts to the early embryonic transcriptome. The Atlantic cod genes included in this study presented diverse transcript expression profiles throughout embryonic and early larval development. For example, adam22 and sacsin transcripts rose abruptly during blastula/gastrula stage and were then expressed at relatively high levels through subsequent embryonic and early larval developmental stages. A peak in irf1 and irf7 transcript expression during early segmentation suggests that these interferon pathway genes play developmental stage specific roles during cod embryogenesis. Stat1 had increasing transcript expression throughout blastula/gastrula, segmentation, and early larval developmental stages. Atf3, cxc chemokine, gaduscidin 1, and il8 transcripts rose approximately 2 3 fold during hatching, supporting the hypothesis that there is preparation at the immune relevant transcript expression level to deal with environmental pathogens that may be encountered during early larval development. The specific roles that interferon pathway and other immune relevant genes play in early life stage cod, and the potential impact of their dynamic transcript expression on immune competence of Atlantic cod embryos and larvae, remain unclear and warrant further study.
Leveraging Linguistic Structure For Open Domain Information Extraction
Venue: ACL
Year: 2015

Relation triples produced by open domain information extraction (open IE) systems are useful for question answering, inference, and other IE tasks. Traditionally these are extracted using a large set of patterns; however, this approach is brittle on out of domain text and long range dependencies, and gives no insight into the substructure of the arguments. We replace this large pattern set with a few patterns for canonically structured sentences, and shift the focus to a classifier which learns to extract self contained clauses from longer sentences. We then run natural logic inference over these short clauses to determine the maximally specific arguments for each candidate triple. We show that our approach outperforms a state of the art open IE system on the end to end TAC KBP 2013
EFFECT OF EMOTIONAL INTELLIGENCE AND ADJUSTMENT ON ACADEMIC ACHIEVEMENT SECONDARY SCHOOL STUDENTS OF DHARWAD DISTRICT
Year: 2020

Adjustment is a process by which a living organism maintains a balance between the needs and the circumstances. For living a happy and prosperous life emotional intelligence and adjustment is a pre requisite condition. In every sphere of life, starting from birth till death we need healthy adjustment. The present study was conducted with the purpose to find out the relationship between emotional intelligence and adjustment on Academic Achievement of Pre secondary school students of Dharwad District. The study was conducted on a sample of 100 Boys and Girls students of 9th class studying in Dharwad District. In the present study, descriptive survey method was employed the collected data was analyzed with the help of correlation. The results of the present study showed that higher the emotional intelligence and the adjustment on Academic Achievement of Pre secondary school students of Dharwad District.
UJI SKRINING DAN DETERMINASI KODEIN DENGAN TLC SPEKTROFOTODENSITOMETRI
Year: 2013

A current research of screening and determination of codeine using Al TLC Spectrophotodensitometry has been carried out. The separation was performed using TAEA mobile phase. Screening and confirmation were investigated by comparing hRfc of the analyte and hRfc those on data library. Combination hRfc vs correlation also been used as confirmation method, which can be enhanced by spectrum shift reaction using HCl 10% and KOH 0,1 M. The validation parameters were precission, linierity, limit of detection and quantitation (LOD LOQ) and recovery. TAEA mobile phase performed a good separation among morphine, codeine, caffeine, papaverine and bromhexine standards, which gave Rs value 1. Test of linierity using regression gave correlation value 0,99 LOD and LOQ of Al TLC were 137.85 ng and 459.63 ng. The recovery of codeine in human plasma using isopropanol as the precipitating agent was 77.1% 4.9 (6.5%
Depletion of 13C in residual ethane and propane during thermal decomposition in sedimentary basins
Year: 2018

Explanations for the thermal decomposition of ethane and propane in sedimentary basins have long been conceptual without quantitative evidence. This work bridges the gap between 13C depletion and the conversion of ethane and propane, and confirms their thermal decomposition during the late catagenesis stage. Isotopic fractionation was rigorously investigated in a partly reversible reaction scheme for ethane and propane decompositions. Analytical solutions under isothermal conditions were derived. Non monotonic isotopic fractionation with respect to conversion is demonstrated, which may be ignored if a steady state approximation is applied. The results imply that depletion of 13C in ethane and propane as their molar fractions decrease (isotopic inverse with respect to thermal maturity) results from the reversible conversion from alkane to alkyl groups. Kinetic parameters were obtained for ethane and propane decomposition in sedimentary basins, and the chemical kinetic method applies to different isotopic fractionation systems. The results help to better understand the chemical form of deep carbon and the thermal conversion of gaseous hydrocarbons in the geochemical carbon cycle.
Positivity approach training for depressive symptoms: A randomized controlled trial.
Venue: Journal of affective disorders
Year: 2019

Depression is highly comorbid and depressive symptoms are very common. Symptom severity adversely affects treatment outcome and later health status. Established interventions for depression leave ample room for improvement. Short interventions that target specific vulnerabilities emerge as plausible augmentation strategies. In this study, we tested the efficacy of a computerized general positivity approach training and its effect on depressive symptoms.  Patients (N 240) with various diagnoses of mental disorders who received treatment as usual in an inpatient setting were randomly assigned to also receive either 4 sessions of a positivity approach training or 4 sessions of sham training. Depression severity was assessed at baseline and post treatment. Training data were analyzed for a subset of 111 patients.  Depressive symptoms were reduced more after positivity approach training than after sham training. Initial depression symptom severity moderated the intervention effects, such that approach tendencies and depression symptoms were only affected positively among patients with higher levels of initial depression symptom severity.  The findings provide preliminary support for positivity approach training as an add on treatment option for depressive symptoms.
Molten chloride technology pathway to meet the U.S. DOE sunshot initiative with Gen3 CSP
Year: 2019

Third generation (Gen3) concentrating solar power (CSP) technologies require a thermally stable and inexpensive fluid to be used for heat transfer and thermal energy storage. For Gen3 CSP plants, a molten salt composed of MgCl2 KCl NaCl is a new candidate, but it is familiar enough to plants with existing molten salt systems. To determine the best composition for the heat transfer fluid, we mixed nine different ratios of the salts, dry/purified them following strict protocols, and tested them with a differential scanning calorimeter and a thermogravimetric analyzer. Our results showed that the lowest melting and solidification temperature of 385degC 1degC was determined for the eutectic composition 44.7 MgCl2 25.8 KCl 29.4 NaCl (mol. We determined that improper handling and preparation of the salt mixture highly affects its thermal properties because of moisture absorption. Preparation standards particularly the dehydration of hydrous MgCl2 merit further development.
KEAMANAN JARINGAN NIRKABEL MENGGUNAKAN WIRELESS INTRUSION DETECTION SYSTEM
Year: 2019

Sistem keamanan jaringan menjadi sangat penting dalam memelihara jaringan, serangan yang dapat mengganggu dan bahkan merusak sistem koneksi antar perangkat yang terhubung akan sangat berbahaya. Untuk mendapatkan keamanan dalam jaringan kadang kadang kita harus merasakan ketidaknyamanan dalam penggunaannya, ini sering menjadi pertimbangan dalam penerapan sistem keamanan jaringan di Kantor Kejaksaan Belitung Timur. WIDS (Wireless Intrusion Detection System) mampu mendeteksi serangan DOS (Denial of Service) Ping Of Deat. Mengimplementasikan pada sistem operasi Linux menggunakan Snort, ACID BASE, Barnyard, pada mesin sensor IDS dan Iptables sebagai penanganan serangan dapat menjadi solusi keamanan jaringan nirkabel dari serangan yang mengancam. Metode penelitian yang saya gunakan adalah metode Siklus Hidup Pengembangan Kebijakan Keamanan (SPDLC) Hasil penelitian ini menyimpulkan bahwa IDS yang diterapkan dapat mendeteksi penyusup atau penyususp pada mesin sensor IDS yang ditampilkan pada BASE (Basec Analysis and Security Engine) Penerapan sistem keamanan jaringan terintegrasi IDS (Intrusion Detection System) berbasis open source. Kata Kunci Wireless, IDS (Intrusion Detection System) Denial of Service, Ping Of Deat, Iptables, Network Security, Linux, Snort, ACID BASE, Barnyard, Security Policy Development Life Cycle.
A Novel Single/Double Precision Normalized IEEE 754 Floating Point Adder/Subtracter
Venue: 2019 IEEE Computer Society Annual Symposium on VLSI (ISVLSI)
Year: 2019

This paper demonstrates the design of a fully IEEE 754 compliant floating point adder and subtractor. This design focuses on creating a high speed, low power design while still adhering completely to the IEEE 754 standard. This design's novelty comes in the form of it's 64 bit prefix adder structure, and the parallelization of it's subcomponents. The adder/subtractor has full support for 32 bit and 64 bit operands, as well as the ability to convert integer operands to the IEEE 754 standard. Synthesis results presented use a cmos32soi 32nm CMOS technology and ARM standard cells.
The mediators of experiential purchases: Determining the impact of psychological needs satisfaction and social comparison
Year: 2009

Once basic needs are satisfied, the relation between income and subjective well being is small, and materialism leads to diminished well being. This study attempts to determine: (1) whether experiential purchases, as opposed to materialistic purchases, are likely to increase well being and (2) whether these increases are likely to be due to increased satisfaction of psychological needs and/or decreased social comparison. Participants indicated that experiential purchases represented money better spent, brought more happiness to themselves, and brought more happiness to others. Path models demonstrated that experiential purchases had an indirect effect on one's well being through two independent paths: (1) increased relatedness, which then led to increased vitality, and (2) decreased social comparison. Discussion focuses on why vitality and social comparison affect well being.
SDN Guard: DoS Attacks Mitigation in SDN Networks
Venue: 2016 5th IEEE International Conference on Cloud Networking (Cloudnet)
Year: 2016

Software Defined Networking (SDN) has recently emerged as a new networking technology offering an unprecedented programmability that allows network operators to dynamically configure and manage their infrastructures. The main idea of SDN is to move the control plane into a central controller that is in charge of taking all routing decisions in the network. However, despite all the advantages offered by this technology, Deny of Service (DoS) attacks are considered a major threat to such networks as they can easily overload the controller processing and communication capacity and flood switch CAM tables, resulting in a critical degradation of the overall network performance. To address this issue, we propose in this paper SDN Guard, a novel scheme able to efficiently protect SDN networks against DoS attacks by dynamically (1) rerouting potential malicious traffic, (2) adjusting flow timeouts and (3) aggregating flow rules. Realistic experiments using Mininet show that the proposed solution succeeds in minimizing by up to 32% the impact of DoS attacks on~the controller performance, switch memory usage and control plane bandwidth and thereby maintaining acceptable network performance during such attacks.
Synergy in ant foraging strategies: memory and communication alone and in combination
Venue: GECCO '13
Year: 2013

Collective foraging is a canonical problem in the study of social insect behavior, as well as in biologically inspired engineered systems. Pheromone recruitment is a well studied mechanism by which ants coordinate their foraging. Another mechanism for information use is the memory of individual ants, which allows an ant to return to a site it has previously visited. There is synergy in the use of social and private information: ants with poor private information can follow pheromone trails; while ants with private information can ignore trails and instead rely on memory. We developed an agent based model of foraging by harvester ants, and optimized the model to maximize foraging rate using genetic algorithms. We found that ants' individual memory provided greater benefit in terms of increased foraging rate than pheromone trails in a variety of food distributions. When the two strategies are used together, they out perform either strategy alone. We compare the behavior of these models to observations of harvester ants in the field. We discuss why individual memory is more beneficial in this system than pheromone trails. We suggest that individual memory may be an important addition to ant colony optimization and swarm robotics systems, and that genetic algorithms may be useful in finding an adaptive balance between individual foraging based on memory and recruitment based on communication.
<Tan diversas y altas sentencias> neoplatonismo y preparacion evangelica en los <Comentarios reales de los Incas>
Venue: Hipogrifo. Revista de literatura y cultura del Siglo de Oro
Year: 2019

Sostener que la traduccion de los Dialogos de amor significo para el Inca Garcilaso un aprendizaje en materia filologica y le procuro un modelo de escritura y traduccion no es una novedad. Sin embargo, no se ha resuelto aun la polemica respecto de cuanta influencia ideologica ejercio el neoplatonismo en su obra mas importante. El presente trabajo explora los alcances de esta doctrina en la articulacion de la primera parte de los Comentarios reales, particularmente en la vision del Inca sobre la vida moral y religiosa andina dentro del proceso de preparacion evangelica. A partir de la nocion platonica de interrelacion entre las partes y el todo, se propone no solo apreciar las fabulas historiales como parte de un esquema mayor, sino tambien leer la historia de los incas desde el mensaje teologico que encierran dichos relatos. En resumidas cuentas, el proposito es evidenciar que el neoplatonismo fue para el mestizo un mecanismo fundamental para transmitir, con la mayor especificidad posible, los matices de la religiosidad andina a su lector sagaz.
Performance based fault detection and fault tolerant control for automatic control systems
Venue: Autom.
Year: 2019

The main focus of this paper is on the analysis and design scheme of performance based fault detection and fault tolerant control for automatic control systems with incipient (slowly developing) multiplicative faults. To this end, the realization form of the multiplicative faults is first studied with the aid of the coprime factorization techniques. Then, the fault tolerant margin is proposed in the closed loop setup aiming at characterizing the fault induced performance degradation. By embedding the fault tolerant margin as a performance indicator, a performance based fault detection approach is developed. Based on the fault detection and the well known controller parameterization form, a control performance based fault tolerant control strategy is investigated. A case study on three tank system is given in the end to illustrate the proposed approaches.
Benefits of Analyzing Prestack Seismic Data Combined with Advanced Interpretation and Visualization Tools to Improve Seismic Reservoir Characterization of Highly Faulted Reservoirs
Year: 2017

Recent advances in software development have enabled seamless use of prestack seismic data combined with advanced attributes and high end interpretation and visualization workflows. We describe a new workflow that gives geophysicists and geologists more flexibility in checking the quality of prestack seismic data and helps them select the best angle stacks for amplitude and structural interpretation. This can be crucial to achieving a better understanding of the prospect geometry and better structural definition. The novelty of this approach is a new workflow to combine the two chosen angle stacks; the one with the most suitable amplitudes, and the one with the best fault detection, using a hybrid cube. This resulting hybrid cube becomes the seed for the second stage of the workflow, which involves the use of advanced interpretation and visualization tools that lead to better seismic reservoir characterization. This approach, coupled with advanced attributes, 3D interpretation, and visualization functionalities, significantly improves prospect delineation, especially in creating a better image of the prospect geometry and better structural definition. This workflow can also help remove the subjectivity around faults interpreted manually and could help in the early stages of modeling, well design and planning.