nils-herrmann/clean_scirepeval huggingface dataset:
Performance Analysis of Hyperledger Fabric Platforms
Venue: Secur. Commun. Networks
Year: 2018

Blockchain is a key technology that has the potential to decentralize the way we store, share, and manage information and data. One of the more recent blockchain platforms that has emerged is Hyperledger Fabric, an open source, permissioned blockchain that was introduced by IBM, first as Hyperledger Fabric v0.6, and then more recently, in 2017, IBM released Hyperledger Fabric v1.0. Although there are many blockchain platforms, there is no clear methodology for evaluating and assessing the different blockchain platforms in terms of their various aspects, such as performance, security, and scalability. In addition, the new version of Hyperledger Fabric was never evaluated against any other blockchain platform. In this paper, we will first conduct a performance analysis of the two versions of Hyperledger Fabric, v0.6 and v1.0. The performance evaluation of the two platforms will be assessed in terms of execution time, latency, and throughput, by varying the workload in each platform up to 10,000 transactions. Second, we will analyze the scalability of the two platforms by varying the number of nodes up to 20 nodes in each platform. Overall, the performance analysis results across all evaluation metrics, scalability, throughput, execution time, and latency, demonstrate that Hyperledger Fabric v1.0 consistently outperforms Hyperledger Fabric v0.6. However, Hyperledger Fabric v1.0 platform performance did not reach the performance level in current traditional database systems under high workload scenarios.
Direct inhibition of osteoblastic Wnt pathway by fibroblast growth factor 23 contributes to bone loss in chronic kidney disease.
Venue: Kidney international
Year: 2016

Bone loss and increased fractures are common complications in chronic kidney disease. Because Wnt pathway activation is essential for normal bone mineralization, we assessed whether Wnt inhibition contributes to high phosphorus induced mineralization defects in uremic rats. By week 20 after 7/8 nephrectomy, rats fed a high phosphorus diet had the expected high serum creatinine, phosphorus, parathyroid hormone, and fibroblast growth factor 23 (FGF23) levels and low serum calcium. There was a 15% reduction in tibial mineral density and a doubling of bone cortical porosity compared to uremic rats fed a normal phosphorus diet. The decreases in tibial mineral density were preceded by time dependent increments in gene expression of bone formation (Osteocalcin and Runx2) and resorption (Cathepsin K) markers, which paralleled elevations in gene expression of the Wnt inhibitors Sfrp1 and Dkk1 in bone. Similar elevations of Wnt inhibitors plus an increased phospho b catenin/b catenin ratio occurred upon exposure of the osteoblast cell line UMR106 01 either to uremic serum or to the combination of parathyroid hormone, FGF23, and soluble Klotho, at levels present in uremic serum. Strikingly, while osteoblast exposure to parathyroid hormone suppressed the expression of Wnt inhibitors, FGF23 directly inhibited the osteoblastic Wnt pathway through a soluble Klotho/MAPK mediated process that required Dkk1 induction. Thus, the induction of Dkk1 by FGF23/soluble Klotho in osteoblasts inactivates Wnt/b catenin signaling. This provides a novel autocrine/paracrine mechanism for the adverse impact of high FGF23 levels on bone in chronic kidney disease.
Fecal progesterone and estrogen metabolite monitoring for cyclicity and pregnancy in southern tamandua (Tamandua tetradactyla)
Venue: Zoo biology
Year: 2020

Reproductive management of the southern tamandua (Tamandua tetradactyla) should include timed introductions for breeding to minimize aggression and pregnancy monitoring. Since serial blood sampling could cause unnecessary stress, and urinary progesterone metabolites are found in very low concentrations, this study sought to validate progesterone and estradiol enzyme immunoassays for measuring fecal progesterone metabolite (FPM) and fecal estrogen metabolite (FEM) concentrations in two females. Peaks in FEM concentrations coincided with breeding and conception, were 5 6 times higher than baseline concentrations, and were followed by clear luteal phases distinguished by FPM concentrations 5 6 times higher than baseline concentrations. FPM concentrations during the first 30 53 days of gestation overlapped with luteal phase concentrations, thereafter increasing to 8 25 times higher than baseline concentrations. FEM concentrations during the first 41 44 days of gestation remained near basal values for one female, whereas concentrations were 1.8 times higher than baseline for the second. FEM concentrations became elevated for the former by 44 days of gestation and increased further for the latter after 53 days, ultimately averaging four times higher than baseline for both females. The biphasic increase in FPM and FEM concentrations, follicular and luteal phase durations (follicular: 7 1 days, luteal: 25 1 days) total cycle length (41 1 days) and gestation (161 165 days) documented in this study were consistent with previous reports from serum and urine analyses. Monitoring FPM and FEM is a reliable noninvasive method for tracking reproductive cycles and pregnancy in southern tamandua that overcomes the challenges associated with serum or urinary hormone analysis.
Comparing short time outcomes of three dimensional and two dimensional totally laparoscopic surgery for colon cancer using overlapped delta shaped anastomosis
Venue: OncoTargets and therapy
Year: 2019

Overlapped delta shaped anastomosis is a newly developed intracorporeal procedure in totally laparoscopic surgery for colon cancer. We explored the safety and efficacy of three dimensional (3D) totally laparoscopic surgery for colon cancer using overlapped anastomosis and compared its short term outcomes with those of two dimensional (2D) surgery.  From January 2016 to March 2018, 97 colon cancer patients were grouped into the 3D group (43 patients) and the 2D group (54 patients) they underwent totally laparoscopic surgery for colon cancer using overlapped anastomosis by 3D and 2D laparoscopy, respectively. Data regarding the clinical characteristics, surgical and pathological outcomes, postoperative recovery and complications were collected and compared.  These two groups were well balanced in terms of age, gender, body mass index, American Society of Anesthesiologists scores, previous abdominal operation history and preoperative chemotherapy (P>0.05) The overall operation time, intraoperative blood loss and removal method of the specimen were similar between groups (P>0.05) but the anastomosis time was significantly shorter in the 3D group than that in the 2D group (P=0.004) There were no differences in terms of pathological outcomes, postoperative recovery and the postoperative complication rates between the groups (P>0.05) Moreover, no mobility related to the anastomosis, such as anastomotic bleeding, stenosis or leakage, occurred in any patient.  3D totally laparoscopic surgery for colon cancer using overlapped delta shaped anastomosis is safe and effective, with satisfactory short term outcomes. In addition, it is less time consuming than 2D surgery regarding the overlapped anastomosis procedure.
Influence of Age, Sex, and Race on College Students' Exercise Motivation of Physical Activity
Venue: Journal of American college health J of ACH
Year: 2011

The authors examined differences in exercise motivation between age, sex, and race for college students.  Students from 156 sections of physical activity classes at a midsize university were recruited (n 2,199; 1,081 men, 1,118 women) in 2005 2006 and volunteered to complete the Exercise Motivation Inventory.  Quantitative, cross sectional descriptive research design was employed.  Significant differences were found in 3 of 14 exercise motivational subscales by age (affiliation, health pressures, and ill health avoidance) (p .05) Males were motivated by intrinsic factors (strength, competition, and challenge) (p .05) and females by extrinsic factors (ie, weight management and appearance) (p .05) only 2 subscales proved not to be significant by sex. Race differences provided 8 significant differences by exercise motivations (p .05)  Significant differences for exercise motivations in college aged population by demographics were documented. Understanding these differences is important for college health professionals for programming strategies and promoting physical activity.
Exploring the relationship between urbanization and the eco environment A case study of Beijing Tianjin Hebei region
Year: 2014

China's high speed economic growth has been characterized by rapid urbanization and a series of environmental issues. This study investigates the urbanization and eco environment system from the perspective of interactive coercing theory and proposes a new comprehensive index system for the assessment of urbanization and the eco environment. This is done using interactive coercing model (ICM) followed by a dynamic coupling coordination degree model (DCCDM) to estimate the relationship between urbanization and the eco environment. This study focuses on the interactive coercing relationship, coupling coordination degree and coordinated patterns in the BTH (Beijing Tianjin Hebei) region, China, with panel data collected from 1980 to 2011. The main conclusions are as follows: (1) demographic urbanization and eco environmental endowment make the greatest contribution to the compound system, indicating that they are the critical factors to consider when analyzing the interactive coercing relationship between urbanization and the eco environment; (2) we find the double exponential curve of urbanization and the eco environment is in the form of an inverted U curve, and thus the Kuznets hypothesis is confirmed by the empirical analysis; and (3) the dynamic of coordination of the selected cities shows an S shaped curve and the corresponding state of the degrees evolves into the rudimentary symbiosis phase from the harmonious development phase during rapid urbanization, and it is revealed that the coordinated patterns of most sample cities are sensitive to the eco environment, which indicates that the urban environment is subject to great pressure. The comprehensive indexes and the interactive coupling models may help the governments better understand the complex coupling relationship, and develop sustainable urbanization development strategies that better balance urbanization and eco environmental protection.
Warp Speed for COVID 19 Vaccines: Why are Children Stuck in Neutral?
Venue: Clinical infectious diseases an official publication of the Infectious Diseases Society of America
Year: 2020

While adult clinical trials of COVID 19 vaccines have moved quickly into Phase 3 clinical trials, clinical trials have not started in children in the US. The direct COVID 19 impact upon children is greater than that observed for a number of other pathogens for which we now have effective pediatric vaccines. Additionally, the role of children in SARS CoV 2 transmission has clearly been underappreciated. Carefully conducted Phase II clinical trials can adequately address potential COVID 19 vaccine safety concerns. Delaying Phase II vaccine clinical trials in children will delay our recovery from COVID 19 and unnecessarily prolong its impact upon children's education, health and emotional well being, and equitable access to opportunities for development and social success. Given the potential direct and indirect benefits of pediatric vaccination, implementation of Phase II clinical trials for COVID 19 vaccines should begin now.
Primary hepatic neuroendocrine tumor: report of one case.
Venue: Translational gastroenterology and hepatology
Year: 2016

Primary hepatic neuroendocrine tumor (PHNET) is extremely rare. In our current case, a 41 year old female was admitted in the department of breast surgery of our center to undergo the radical resection of right breast cancer 2 weeks ago. The pre operative examinations did not show any liver space occupying lesion. She had no carcinoid syndrome. Liver contrast enhanced MRI showed that the tumor was remarkably enhanced in the arterial phase; an adenoma was considered, although the possibility of malignancy could not be excluded. She had a previous history of high blood pressure for 3 years, and the blood pressure was maintained around 130/80 mmHg by oral medications. She was allergic to penicillin. She underwent right hemihepatectomy in the department of hepatobiliary surgery in our center. Postoperative pathology confirmed that the lesion was a neuroendocrine tumor (NET) Post operative somatostatin receptor (SSTR) scintigraphy, 18F FDG, PET/CT, 68Ga DOTA TATE PET/CT did not reveal any definite tumor sign in liver or other sites. The patient was diagnosed as PHNET, which was treated by radical resection.
From spiral cleavage to bilateral symmetry: The developmental cell lineage of the annelid brain
Year: 2018

The spiral cleavage pattern is characteristic for Spiralia (Lophotrochozoa) a large assembly of marine invertebrates. In most cases, spiral cleavage produces freely swimming, trochophora type larvae with a simple nervous system that controls ciliary locomotion. These larvae acquire bilateral symmetry, as manifested for example in the larval brain. The transition from the rotational symmetry of spiral cleavage into the bilateral adult body has not yet been understood. Here, we present the developmental cell lineage of the brain of the annelid Platynereis dumerilii from the zygote until the mid trochophore stage ~30 hpf) in combination with a gene expression atlas for several embryonic and larval stages. Comparison of multiple embryos reveals a highly stereotypical development and an invariant cell lineage of the differentiated cell types. In addition, we observe a fundamental subdivision of the larval brain into a highly proliferative dorsolateral region and an early differentiating ventromedial region that gives rise to the apical nervous system. The transition from rotational to bilateral symmetry progresses gradually from the lateral to the central regions. Strikingly, the spiral to bilateral transition does not involve extensive cell migration. Rather, corresponding cells in different spiral quadrants acquire highly divergent identities in line with their bilateral position.
Back Propagated Neural Network on MapReduce Frameworks: A Survey
Year: 2019

Back propagated Neural Network (BPNN) is a popular supervised learning technique utilized in machine learning and deep learning to extract knowledge. However, BPNN has shown poor time and space complexity with large volume of data due to its in memory processing. Huge amount of data sourced by ample of applications and services on the Internet needs to be distributed and parallel environment like MapReduce framework for processing and storage. The large volume of data is divided into smaller chunks and MapReduce framework exploits the cluster of commodity hardware to process these chunks. This research focuses on various MapReduce based BPNN algorithms such as single pass and multi pass MapReduce based BPNN. The research is intended to perform in depth comparisons of these techniques considering various parameters such as computation complexity of Mapper and Reducer, granularity of Mapper's output, number of MapReduce jobs required to build BPNN, and Mapper's pairs.
Blind Source Separation Algorithm for Chaotic Masking Multipath Signals Based on Spectral Peak Search Counter Permutation
Venue: IEEE Access
Year: 2020

Since voice communication is the main method of information transmission, it is important to ensure the safety and efficiency of voice communication. In this paper, a more complex multipath channel model in a wireless environment is considered, and chaotic masking technology is used to ensure the security of voice signal transmission. Based on this, a multipath blind source separation algorithm based on cross correlation permutation of spectral peak search counters is proposed. First, chaotic masking is performed between multiple voice signals and chaotic signal, and an impulse response filter is used to simulate the multipath transmission process. Next, the short time Fourier transform is employed to convert the observation signal into a frequency domain signal. Then, the joint approximate diagonalization of eigen matrix algorithm is used to perform linear instantaneous blind source separation at each frequency. And to solve the permutation uncertainty problem in the frequency domain method, a cross correlation permutation algorithm based on a spectral peak search counter is proposed. Finally, the permuted signal is transformed back to the time domain to get the estimated source signal by the inverse short time Fourier transform. And simulation experiments show that the algorithm greatly reduces the calculation amount of the autocorrelation coefficient in the traditional permutation algorithm. Moreover, the permutation algorithm has stability and accuracy, and provides a solution for the secure transmission and effective separation of voice signals in multipath transmission channels.
The role of molecular modelling and simulation in the discovery and deployment of metal organic frameworks for gas storage and separation*
Venue: Molecular simulation
Year: 2019

Metal organic frameworks (MOFs) are highly tuneable, extended network, crystalline, nanoporous materials with applications in gas storage, separations, and sensing. We review how molecular models and simulations of gas adsorption in MOFs have informed the discovery of performant MOFs for methane, hydrogen, and oxygen storage, xenon, carbon dioxide, and chemical warfare agent capture, and xylene enrichment. Particularly, we highlight how large, open databases of MOF crystal structures, post processed to enable molecular simulations, are a platform for computational materials discovery. We discuss how to orient research efforts to routinise the computational discovery of MOFs for adsorption based engineering applications.
Physical therapist s performance in Cerests indicators of notification of work related musculoskeletal disorders
Year: 2017

Corresponding address: Bruna Ferreira Melo Avenida Cardeal da Silva, 447, Edificio Studio Avant Garde, ap. 1206, Federacao Salvador (BA) Brazil Zip  There was no funding from research promotion agency Conflict of interest: None of the authors presents a conflict of interest in the execution and publication of this article.  May 2016  Mar. 2017 Approved by Research Ethics Committee of the Instituto de Ciencias da Saude of Universidade Federal da Bahia on advice n. 926.102. DOI: 10.1590/1809 2950/16439824022017
Long Term Outcome of Cognitive Behavior Therapy for Body Dysmorphic Disorder: A Naturalistic Case Series of 1 to 4 Years After a Controlled Trial.
Venue: Behavior therapy
Year: 2015

There is some evidence for the efficacy of cognitive behavior therapy (CBT) for body dysmorphic disorder (BDD) after 1 to 6months but none in the long term. The aim of this study was to follow up the participants in a randomized controlled trial of CBT versus anxiety management to determine whether or not the treatment gains were maintained over time. Thirty of the original 39 participants who had CBT were followed up over 1 to 4years and assessed using a number of clinician and self report measures, which included the primary outcome measure of the Yale Brown Obsessive Compulsive Scale modified for BDD. Outcome scores generally maintained over time from end of treatment to long term follow up. There was a slight deterioration from n=20 (51.3% to n=18 (46.2% who met improvement criteria at long term follow up. Eleven (28.2% were in full remission and 22 (56.4% were in partial remission. The gains made were generally maintained at long term follow up. However, there were a significant number of participants who maintained chronic symptoms after treatment and may need a longer term or more complex intervention and active medication management.
Childhood interpersonal violence and adult alcohol, cannabis, and tobacco use disorders: variation by race/ethnicity?
Venue: Psychological Medicine
Year: 2018

Exposure to child maltreatment has been shown to increase lifetime risk for substance use disorders (SUD) However, this has not been systematically examined among race/ethnic groups, for whom rates of exposure to assaultive violence and SUD differ. This study examined variation by race/ethnicity and gender in associations of alcohol (AUD) cannabis (CUD) and tobacco (TUD) use disorders with three types of childhood interpersonal violence (cIPV) physical abuse, sexual abuse, and witnessing parental violence.  Data from the National Epidemiologic Survey of Alcohol Related Conditions III (N: 36 309) a US nationally representative sample, was utilized to examine associations of DSM 5 AUD, CUD and TUD with cIPV among men and women of five racial/ethnic groups. Models were adjusted for additional risk factors (e.g. parental substance use problems, participant's co occurring SUD) Results Independent contributions of childhood physical and sexual abuse to AUD, CUD, and TUD, and of witnessing parental violence to AUD and TUD were observed. Associations of cIPV and SUD were relatively similar across race/ethnicity and gender [Odds Ratios (ORs) ranged from 1.1 to 1.9] although associations of physical abuse with AUD and TUD were greater among males, associations of parental violence and AUD were greater among females, and associations of parental violence with AUD were greater among Hispanic women and American Indian men.  Given the paucity of research in this area, and the potential identification of modifiable risk factors to reduce the impact of childhood interpersonal violence on SUDs, further research and consideration of tailoring prevention and intervention efforts to different populations are warranted.
The Current and Future Status of IoT Security Challenges in Practice
Venue: Indian Journal of Science and Technology
Year: 2019

This study presents IoT security features, IoT security layers' challenges with application layer and network layer.  Major security concerns of IoT development are caused by heterogeneity of interconnected entities as well as incompatibility of development and communication protocols used. Authentication, integrity, and availability are compromised by such attacks as man in the middle, replay, and denial of services attacks. Looking into the future, blockchain and software defined network technologies, are promising to deliver a more secured IoT operational environment, and could, therefore, reduce associated cyber attack instances.  Furthermore, IoT security solution with current IoT security arrangements incorporate trust foundation, a move towards a united design and architecture is also discussed. Author for correspondence
A survey on analysis of human faces and facial expressions datasets
Venue: Int. J. Mach. Learn. Cybern.
Year: 2020

Facial expressions are the basic input for visual emotion detection. They are of great importance in computer vision society. In last decade, substantial amount of work has been done in the field of facial expressions datasets. This survey covers all of the publically available databases in detail and provides necessary information about these sets. This review delivers comprehensive support to researchers in selection of their desired dataset. The datasets are organized in decreasing order of their importance with respect to diversity in expressions, poses, number of images and resolution. This survey also provides comprehensive tabular comparison of different face based databases.