nils-herrmann/clean_scirepeval huggingface dataset:
Transcript origin analysis identifies antigen presenting cells as primary targets of socially regulated gene expression in leukocytes
Venue: Proceedings of the National Academy of Sciences
Year: 2011

To clarify the biological rationale for social regulation of gene expression, this study sought to identify the specific immune cell types that are transcriptionally sensitive to subjective social isolation (loneliness) Using reference distributions for the expression of each human gene in each major leukocyte subtype, we mapped the cellular origin of transcripts found to be differentially expressed in the circulating immune cells from chronically lonely individuals. Loneliness associated genes derived primarily from plasmacytoid dendritic cells, monocytes, and, to a lesser extent, B lymphocytes. Those dynamics reflected per cell changes in the expression of inducible genes and related more strongly to the subjective experience of loneliness than to objective social network size. Evolutionarily ancient myeloid antigen presenting cells appear to have evolved a transcriptional sensitivity to socioenvironmental conditions that may allow them to shift basal gene expression profiles to counter the changing microbial threats associated with hostile vs. affine social conditions.
Analysis of the Influence of Competence and Workload on Employee Performance Mediated by Working Stress at PT Pelabuhan Indonesia IV (Persero) Branch of Jayapura
Year: 2018

The current organizational paradigm is toward looking at human resources as an investment that will add value to the organization not only to survive, but at the same time lead in an environment full of predictions and anticipations through an effort to create creativity and innovation of human resources) This study aims to determine the influence of competence, workload, and work stress on employee performance and how the competence and workload affect the employee performance through job stress at PT Pelabuhan Indonesia IV (Persero) Branch Jayapura. The type of research used in this study is quantitative approach. The quantitative approach bases the study of empirical rational principles. The quantitative approach bases the study of empirical rational principles. Problems and hypotheses to be tested based on defined criteria as well as path analysis tools ie Smart PLS 2.0 to know the relation of variables. The results showed that partially competence has a positive and significant effect on employee performance, work load has a positive and significant effect on employee performance, and work stress have positive and significant effect to employee performance. For indirect influence, competence and workload have a positive and significant effect on employee performance through work stress at PT Pelabuhan Indonesia IV (Persero) Branch of Jayapura.
FROM THE PLAY DIE DREIGROSCHENOPER TO OPERA IKAN ASIN: A STUDY ON HANS ROBERT JAUSS' HORIZON OF EXPECTATION
Year: 2020

This article aims to reveal how Riantiarno's horizon of expectation before reading the play Die Dreigroschenoper affects the results of his actualization in his play Opera Ikan Asin The method that being used here is comparison and literature study method. The results show that not all of Riantiarno's expectation were fullfiled. To fullfill the horizon of expectation, Riantiarno makes and adjustment. The unfulfillment in terms of theater norms have led to the inclusion of traditional elements into the play Opera Ikan Asin Therefore, Brecht's play Die Dreigroschenoper gets Riantiarno closer to the tradition.
Review on the Symposium of Li Da zhao and CPC the Commemoration of the Ninety Anniversary of the Founding of CPC
Year: 2011

LI Da zhao is a pioneer of Chinese Communist Movement and one of the earliest Marxist as well as one of the founders of CPC.Because of his unique position and contribution in history,the symposium of Li Da zhao and CPC the commemoration of the ninety anniversary of the founding of CPC was held on April 28th,2011,the approaching time of ninety anniversary of the establishment of the Chinese Communist Party and the 84th anniversary of the heroic martyrdom of LI Da zhao,in order to commemorate his great achievements,to further stimulate the love toward Party and patriotic feeling,to promote the scientific development and advance the progress of prosperous people and strong province.It was hosted by Publicity Department of CPC Hebei Provincial Party Committee,Hebei Academy of Social Science and CPC Tangshan Municipal Committee and organized by Publicity Department of CPC Tangshan Municipal Committee and Lauting County Party Committee.All the representatives made a comprehensive study on the great achievements of LI Da zhao,agreed that the meeting is a brand new start to learn LI Da zhao,to research on him,to advocate and carry forward his spirit.It is necessary to continue the research and the advocation of LI Da zhao.
Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics)
Venue: Omics a journal of integrative biology
Year: 2014

This article announces the recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine by the Pacific Rim Association for Clinical Pharmacogenetics (PRACP) Bernard Lerer, professor of psychiatry and director of the Biological Psychiatry Laboratory, Hadassah Hebrew University Medical Center,  The Werner Kalow Responsible Innovation Prize is given to an exceptional interdisciplinary scholar who has made highly innovative and enduring contributions to global omics science and personalized medicine, with both vertical and horizontal (transdisciplinary) impacts. The prize is established in memory of a beloved colleague, mentor, and friend, the late Professor Werner Kalow, who cultivated the idea and practice of pharmacogenetics in modern therapeutics commencing in the 1950s. PRACP, the prize's sponsor, is one of the longest standing learned societies in the Asia Pacific region, and was founded by Kalow and colleagues more than two decades ago in the then emerging field of pharmacogenetics. In announcing this inaugural prize and its winner, we seek to highlight the works of prize winner, Professor Lerer. Additionally, we contextualize the significance of the prize by recalling the life and works of Professor Kalow and providing a brief socio technical history of the rise of pharmacogenetics and personalized medicine as a veritable form of 21(st) century scientific practice. The article also fills a void in previous social science analyses of pharmacogenetics, by bringing to the fore the works of Kalow from 1995 to 2008, when he presciently noted the rise of yet another field of postgenomics inquiry pharmacoepigenetics that railed against genetic determinism and underscored the temporal and spatial plasticity of genetic components of drug response, with invention of the repeated drug administration (RDA) method that estimates the dynamic heritabilities of drug response. The prize goes a long way to cultivate transgenerational capacity and broader cognizance of the concept and practice of responsible innovation as an important criterion of 21(st) century omics science and personalized medicine. A new call is presently in place for the 2016 PRACP Werner Kalow prize. Nominations can be made in support of an exceptional individual interdisciplinary scholar, or alternatively, an entire research team, from any region in the world with a record of highly innovative contributions to global omics science and/or personalized medicine, in the spirit of responsible innovation. The application process is straightforward, requiring a signed, 1500 word nomination letter (by the applicant or sponsor) submitted not later than May 31, 2015.
NOAA QC Tools Origin Development and Future
Year: 2016

Advancing multibeam technology allows us to map the seafloor better than ever before, and we have plenty of stunning bathymetry to show for it. Yet the ever increasing data volume presents some challenges during both quality review and in its generalization to nautical chart scale. Specific challenges and inefficiencies in these processes are addressed with NOAA QC tools, specifically: 1) "flier finder" which scans gridded bathymetry and flags anomalous data "fliers" for easy identification and removal, 2) feature scans, to ensure proper attribution and accurate representation within gridded bathymetry, and 3) an automated method of comparing survey soundings to those charted, as a formal means of chart comparison, identification of dangers to navigation, and also in the evaluation of a prospective chart sounding selection. This paper discusses the QC tools listed above, with regards to: 1) their organic development within NOAA, to alleviate redundant, manually intensive tasks better suited for automation, 2) their implementation into the Rapid Survey Assessment (RSA) process of the NOAA Hydrographic Surveys Division (HSD) 3) their joint development with the Center for Coastal and Ocean Mapping Joint Hydrographic Center (CCOM/JHC) through their integration within the HydrOffice research framework, and 4) future and ongoing improvements. Proposed innovation includes flier identification through a multi detector algorithm, a "smart" chart sounding selection, and a wide range of task specific applications to facilitate all phases of ocean mapping.
Human Capital and Economic Growth of Pakistan
Year: 2016

Human capital consists of set of resources which define individuals' overall ability and includes skills, education, training, health and other talents. These abilities collectively shape up the potential of citizens of a country and help in charting the course of economic growth and development of that country. The ranking of Pakistan in terms of human capital index is reported to have dropped to 113 from 109 out of 124 countries (Human Capital Report 2014 2015) and thus requires a lot of attention. The main aim of this paper is to investigate the relationship between human capital and economic growth in Pakistan. Explaining human capital by the proxies of primary enrolments rate, birth rate, and infant mortality rate, this paper confirms the role of human capital in promoting development in Pakistan. Physical capital was used as a fixed capital and one of the factors of production. Result indicates that the two main sectors which need considerable amount of attention are education and health. This objective can be achieved by allocating high percentage of GDP to these sectors
The impact of perceived lack of support provided by health and social care services to caregivers of people with motor neuron disease
Venue: Amyotrophic lateral sclerosis official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases
Year: 2012

Our objective was to investigate the relationship between support by health and social care services and caregiver well being. A survey, including a generic health status measure (SF 12) a disease specific measure for patients (ALSAQ 40) the Carer Strain Index (CSI) for caregivers and questions on experiences of health and social care services, was sent to patient members of the MND Association (UK) and their caregivers. A single 'problem score' was calculated from the experience questions and the relationship between the problem score with caregiver and patient well being was analysed. Most caregivers reported at least one problem with support from services. The most common problems were services not valuing caregivers' experiences, and caregivers not feeling sufficiently involved in planning care. The problem score significantly increased with increasing caregiver strain and worsening mental health. The problem score was also increased as patient well being decreased. The results suggest that caregiver strain was higher and mental health lower as the number of problems reported increased. A higher perceived lack of caregiver support was also related to a decrease in patient well being, suggesting that caregivers' needs increase as the disease progresses. This emphasizes the importance of MND caregivers being appropriately supported by health and social care services in their caregiving role.
Renk Teorisi ve Temel Yanilgilar
Year: 2012

Her ne kadar gunumuz literaturunde cogunlukla Sari, Kirmizive Mavi'den ana renk olarak bahsedilse de pigmentlerle uretim yapan basim teknolojilerinde birincil ana renk olarak Siyan Mavi, Macenta ve Sarikullanilmaktadir. Bu ana pigmentler deki Siyan Mavi, Macenta ve Sari'nin ikiserli karisiminda ise ikincil ana pigment renkleri olarak Kirmizi, Yesil ve Koyu Mavi, elde edilmektedir. Ana renk ne demektir? Gercekte ana renkler nelerdir? Sari, kirmizive mavi ana renkler midir? Ana renk denilen mavi nasil bir mavidir? Kirmizipigmentte mi isikta miana renktir? Isik ana renkleri ile pigment ana renkleri neden birbirinden farklidir? Bu arastirma yukaridaki sorulara yanit aramakla birlikte, kaynaklarda birbirleri ile celisen renk teorilerinin detaylianalizini yaparak gunumuz bilim ve teknolojileri isiginda dogru olan ana ve ara renkleri ortaya koymayiamaclamaktadir. Ve renk teorilerinin anlatildigikaynaklardaki celiskiler ile bilimsel olarakana, ara ve tamamlayicirenkleri ortaya koymasiacisindan aynizamanda bu alanda yapilacak gelecek calismalara kaynaklik etmesi bakimindan onemlidir. Gecmiste deneyimlere dayaliifade edilmeye calisilan renk teorileri, gunumuzde bilim ve teknolojilerdeki gelismelerle daha kapsamliaciklanabilmektedir. Ozellikle Young'in gorme fizyolojisine yonelik incelemeleri ve renk algisinigerceklestiren koni hucrelerinin fonksiyonunu aciklamasive Helmholtz'un, Newton'un da ortaya koydugu rengin, fizik deneylerinin sagladigibirikimle uc renkli kuraminiortaya koymustur. Isaac Newton ve Thomas Young'un deneylerinden ortaya cikan sonuclara gore beyaz isigin gunesin tum renklerini icinde barindirdiginisoyleyebiliriz. Isik,tumbeyaz isigigozumuze yansitan bir objeye dustugunde, o obje gozumuze beyaz renkli olarak gorunur. Young yaptigideneylerde uyguladigieleme yontemleriyle tayfin altirenginin, yine aynitayfta yer alan uc temel (kirmizi, yesil ve koyu mavi) renge indirgenebilecegini bulmustur. Ayrica bu uc rengi ikiser ikiser karistirarak diger uc renk, yani: siyan mavisi, macenta ve sarirenklerin de elde edilebilecegini ispatlamistir. Bu uc renk kendi icerisinde degisik oranlarda katilarak doganin sonsuz renkleri elde edilebilir.
Kawalan Imigresen dan Pembentukan Negara: Perkembangan dan Perubahan di Tanah Melayu Daripada Zaman Kesultanan Melaka Ke Era Malaysia Moden (Immigration Control and State Formation; Development and Changes In Malaya From Malacca Sultanate To Malaysian Modern Era)
Year: 2019

Migration is one of the key factors in the formation of a state over a long period of time. Migration control is a prerequisite to ensuring the existence of a country on its own identity. For Malaya, British was responsible for establishing the Immigration Department and gradually introducing immigration control at border checkpoints in legal aspect and procedures in order to control the entry of migrants and to assist economic development. Although the establishment of organized immigration control can be traced back to the era of British government, the fact is that its concept and practice generally existed as early as the Malacca Malay sultanate, which regulated a vast foreign trade activities and collected tax through the port. The development of immigration control after independence until today focused more on coordination of policies and legislation as well as modernization of the system and technology within the Immigration Department of Malaysia as the agency that enforces control of foreigners' entry at the border checkpoints. This article collects information and data from feedbacks gathered from senior officials in the Immigration Department of Malaysia as well as literatures in the history, legal and social sciences. The main focus of this article is the changes in the border checkpoint control system in Malaya due to the process of state formation which includes the colonization, economic, security, migration, legislation and consolidation of the Malayan territories, Singapore, Sabah and Sarawak which eventually formed Malaysia. All of these factors gradually formed a system of immigration control from one simple process during Malacca era to a complete and advance process with legislations and the role of specific agencies.
On Anatomical Enumeration and Difference in Early Sanskrit Medical Literature
Year: 2020

What does it mean to inventory all the components of the human body, and what do those inventories tell us about medical ideas and practice? I compare the lists of body parts in the sarira sthanas (sections relating to the body) of the Caraka samhita (ca. first century CE) and the Susruta samhita (ca. second century CE) Rather than provide a detailed list of differences, I contemplate what these differences "mean" in terms of counting as a practice and of how we might think about these two texts as articulations of the concerns of the "theorist physicians" of the Caraka samhita and the "anatomist surgeons" of the Susruta samhita. How might a close comparative reading of these passages an "emic" reading, if you will shed light on medical practice in early India and its relationship with metaphysical concerns, issues of selfhood, sexual "difference," and the problem of understanding what cannot be seen with the naked eye?
Genetic Diversity and Signatures of Selection for Thermal Stress in Cattle and Other Two Bos Species Adapted to Divergent Climatic Conditions
Venue: Frontiers in Genetics
Year: 2021

Understanding the biological mechanisms of climatic adaptation is of paramount importance for the optimization of breeding programs and conservation of genetic resources. The aim of this study was to investigate genetic diversity and unravel genomic regions potentially under selection for heat and/or cold tolerance in thirty two worldwide cattle breeds, with a focus on Chinese local cattle breeds adapted to divergent climatic conditions, Datong yak (Bos grunniens; YAK) and Bali (Bos javanicus) based on dense SNP data. In general, moderate genetic diversity levels were observed in most cattle populations. The proportion of polymorphic SNP ranged from 0.197 (YAK) to 0.992 (Mongolian cattle) Observed and expected heterozygosity ranged from 0.023 (YAK) to 0.366 (Sanhe cattle; SH) and from 0.021 (YAK) to 0.358 (SH) respectively. The overall average inbreeding SD) was: 0.118 0.028, 0.228 0.059, 0.194 0.041, and 0.021 0.004 based on the observed versus expected number of homozygous genotypes, excess of homozygosity, correlation between uniting gametes, and runs of homozygosity (ROH) respectively. Signatures of selection based on multiple scenarios and methods (FST, HapFLK, and ROH) revealed important genomic regions and candidate genes. The candidate genes identified are related to various biological processes and pathways such as heat shock proteins, oxygen transport, anatomical traits, mitochondrial DNA maintenance, metabolic activity, feed intake, carcass conformation, fertility, and reproduction. This highlights the large number of biological processes involved in thermal tolerance and thus, the polygenic nature of climatic resilience. A comprehensive description of genetic diversity measures in Chinese cattle and YAK was carried out and compared to 24 worldwide cattle breeds to avoid potential biases. Numerous genomic regions under positive selection were detected using three signature of selection methods and candidate genes potentially under positive selection were identified. Enriched function analyses pinpointed important biological pathways, molecular function and cellular components, which contribute to a better understanding of the biological mechanisms underlying thermal tolerance in cattle. Based on the large number of genomic regions identified, thermal tolerance has a complex polygenic inheritance nature, which was expected considering the various mechanisms involved in thermal stress response.
Eyes to see and ears to hear: sensitivity in research on attachment and culture
Venue: Attachment human development
Year: 2020

How and why should attachment researchers engage in research on attachment and culture? How should they strive to develop a theoretical perspective that is both contextually sensitive and also reflecting species typical processes of evolutionary adaptation? These comments on the remarkable empirical papers of this special issue consider what is learned from these studies, what more is needed, and directions for future research.
What does quality of life refer to in bipolar disorders research? A systematic review of the construct's definition, usage and measurement.
Venue: Journal of affective disorders
Year: 2017

Quality of life (QoL) is increasingly investigated in bipolar disorders (BD) research, yet little attention has been paid to its optimal definition and measurement. This is a significant limitation, as the broader QoL literature recognises a number of divergent meanings and measurement tensions. The aim here was to advance understanding of QoL in BD by clarifying use of the construct in the existing literature and considering measurement implications.  Thematic analysis techniques were used to interrogate articles identified via systematic search for (a) explicit discussion of QoL definitional/measurement issues, and (b) usage of the term QoL.  A total of 275 articles were included in the analysis. A range of definitional and methodological issues confounding the study of QoL in BD were identified. While explicit definition of QoL proved rare, thematic analysis of usage of the construct revealed the concepts of functioning, health, subjective experience and wellbeing were thought to be relevant to QoL in BD.  The review does not engage in top down theory development. Our analysis was grounded in the empirical literature to support future theoretical work relevant to existing usage of QoL in BD.  There was no evidence of a consensus definition of QoL in BD. A plurality of QoL definitions is not necessarily a flaw in the literature, but points to empirical and conceptual issues demanding attention. Awareness of the diversity of constructs associated with QoL will enable clinicians to better select treatments on the basis of specific QoL outcomes. A research agenda and provisional considerations for empirical research are outlined based on the present analyses.