nils-herrmann/clean_scirepeval huggingface dataset:
Ophthalmic Drug Dosage Forms: Characterisation and Research Methods
Venue: TheScientificWorldJournal
Year: 2014

This paper describes hitherto developed drug forms for topical ocular administration, that is, eye drops, ointments, in situ gels, inserts, multicompartment drug delivery systems, and ophthalmic drug forms with bioadhesive properties. Heretofore, many studies have demonstrated that new and more complex ophthalmic drug forms exhibit advantage over traditional ones and are able to increase the bioavailability of the active substance by, among others, reducing the susceptibility of drug forms to defense mechanisms of the human eye, extending contact time of drug with the cornea, increasing the penetration through the complex anatomical structure of the eye, and providing controlled release of drugs into the eye tissues, which allows reducing the drug application frequency. The rest of the paper describes recommended in vitro and in vivo studies to be performed for various ophthalmic drugs forms in order to assess whether the form is acceptable from the perspective of desired properties and patient's compliance.
Risk preference dynamics around life events
Venue: Journal of Economic Behavior Organization
Year: 2019

Using a panel of Australians I estimate the dynamic relationship between common life events and risk preferences. Changes in financial circumstances, parenthood and family loss predict changes in risk preferences. Importantly the effects are largest closer to the event date and disappear over time. This supports a model of preference information where risk preferences are (trend) stable but fluctuations are at least partly deterministic. The linkages between life events and risk preferences are explored. There is little evidence that changes in consumption, state dependence, or changes in mental health and mood explain the results. However, emotional stability is an influential moderator suggesting that emotions play an important role.
Sequenced application of glutathione as an antioxidant with an organic biostimulant improves physiological and metabolic adaptation to salinity in wheat.
Venue: Plant physiology and biochemistry PPB
Year: 2020

Globally, salinity threatens the agricultural crops productivity by inhibiting plant growth and development through osmotic stress and ionic cytotoxicity. The polygenic nature of salinity offers several pragmatic shotgun approaches to improve salinity tolerance. The present study investigated the potential of glutathione (GSH; 1 mM) as an antioxidant and moringa leaf extract (MLE; 3% as an organic biostimulant applied in sequence as seed priming and foliar spray on wheat growth, physiology and metabolic adaptation under saline conditions (9.16 dS m 1) Plants without any treatment and water spray (H2O) were considered controls. Salinity induced osmotic stress reduced the plant tissue water status and photosynthetic performance, and perturbed ionic (K+/Na+ Ca2+/Na+ K++Ca2+/Na+ and hormonal (IAA, GA3, zeatin, ABA) homeostasis, consequently affected growth and yield in wheat. Sequenced applied MLE and/or GSH improved osmotic stress tolerance by stabilizing membrane integrity and decreasing electrolyte leakage. These positive results were owed to enhanced endogenous GSH and ascorbate levels. Improved tissue water status was attributed to increased osmotic adjustment, better ionic and hormonal homeostasis contributed to improving photosynthetic efficiency and growth under salinity. Exogenously applied MLE and GSH sequences improved grain yield, which was attributed to the maintenance of green leaf area and delayed senescence associated with an increase in photosynthetic pigments and chlorophyll fluorescence traits. In crux, exogenous applied MLE and/or GSH can be the best physiological strategy to reduce the deleterious effects of salinity and improve physiological and metabolic adaptation in wheat under saline field conditions.
Conditions for formation and trapping of the two ion Coulomb cluster in the dissipative optical superlattice
Year: 2015

Conditions have been studied under which a polychromatic optical superlattice can form and trap the Coulomb cluster of two strongly interacting ions. In our previous work (Krasnov I V and Kamenshchikov L P 2014 Opt. Comm. 312 192) this new all optical method of obtaining and confining the Coulomb clusters was demonstrated by numerical simulations for special values of the optical superlattice parameters and in the case of Yb ions. In the present paper the conditions are explicitly formulated, under which the long lived two ion cluster in the superlattice cell is formed. The peculiarity of these conditions is the renormalization of the ion ion Coulomb interaction. Notably, the renormalized Coulomb force is determined by the effective charge which depends on the light field parameters and can strongly differ from the "bare" ion charge. This result can be accounted for by the combined manifestation of the quantum fluctuations of optical forces, nonlinear dependence of these forces on the velocity, and non Maxwellian (Tsallis type) velocity distribution of the ions in the optical superlattice. Explicit analytical formulas are also obtained for the parameters of the optical two ion cluster.
Cyberbullying: relationship with developmental variables and cyber victimization#
Venue: Scandinavian journal of child and adolescent psychiatry and psychology
Year: 2020

Cyberbullying is increasingly turning into a significant problem for children and adolescents due to its adverse psychological and academic outcomes. In the present study, the protective and risk factors for cyberbullying has been investigated. One of the aims of the study was to examine the relationship between peer relations, negative emotion regulation strategies, and cyberbullying. The successful identity development process is thought to influence both cyberbullying behaviors as well as adolescents' peer relations and emotion regulation. Also, cyber victimization is seen as a risk factor for cyberbullying. The second aim of the study is to investigate the causal relationship between cyber victimization and cyberbullying.  The study is a descriptive research in which both cross sectional and longitudinal data were used. In the cross sectional part of the study, 1,151 adolescents have participated, and the data of the second wave was obtained from 322 of them four months later. Data were analyzed through structural equation modeling (SEM) and hierarchical regression analyses.  According to the results of SEM, good peer relations predicted less cyberbullying. The expressive repression explained the cyberbullying through peer relationships. For identity development, contrary to expectations, commitment dimension of identity seemed to be positively related to more cyberbullying and so did higher reconsideration of commitment. Cross lagged panel analyses revealed that Time 1 cyber victimization predicted Time 2 cyberbullying. Given the pattern of cross lagged relationships, it was tentatively inferred that cyber victimization was the temporal precursor to cyberbullying. The results of the study have implications for the prevention of cyberbullying.
Differential effects of credit risk and capital adequacy ratio on profitability of the domestic banking sector in Ghana
Year: 2019

Examining credit risk and banks' solvency effects on profitability are essential for overall health of the banking sector. However, earlier studies on these nexuses are not instructive given their failure to examine how credit risk and capital adequacy levels impact on profitability for the different types of banks. In addition to re examining the effect of credit risk and capital adequacy ratio (CAR) on profitability of the overall banking sector, this study aims at determining their differential effects on profitability of local and foreign banks within Ghana's banking sector. The study relies on data from 11 banks spanning 2006 2016 while employing the fixed effects estimation approach. Results from the study show a positive and significant effect of credit risk on profitability with huge effect for local relative to foreign banks. However, CAR negatively affects profitability of foreign banks with no apparent impact on local banks.
Entrevista a Pedro Cifuentes: <La innovacion pasa por cambiar la mirada, ensenar a ser creativos mediante el uso de comics, narrativa grafica e imaginacion>
Year: 2021

El dibujo es un recurso comunicativo universal e inclusivo que se puede hermanar con la edicion, es decir: la labor de maquetar textos, hacerlos bonitos, atractivos a la vista, de redactarlos y de explicar bien las cosas con ellos. Como puedes ver, son aspectos que tienen mucho en comun con lo que demandamos a nuestros alumnos
Surface structured bacterial cellulose with guided assembly based biolithography (GAB)
Venue: ACS nano
Year: 2015

A powerful replica molding methodology to transfer on demand functional topographies to the surface of bacterial cellulose nanofiber textures is presented. With this method, termed guided assembly based biolithography (GAB) a surface structured polydimethylsiloxane (PDMS) mold is introduced at the gas liquid interface of an Acetobacter xylinum culture. Upon bacterial fermentation, the generated bacterial cellulose nanofibers are assembled in a three dimensional network reproducing the geometric shape imposed by the mold. Additionally, GAB yields directional alignment of individual nanofibers and memory of the transferred geometrical features upon dehydration and rehydration of the substrates. Scanning electron and atomic force microscopy are used to establish the good fidelity of this facile and affordable method. Interaction of surface structured bacterial cellulose substrates with human fibroblasts and keratinocytes illustrates the efficient control of cellular activities which are fundamental in skin wound healing and tissue regeneration. The deployment of surface structured bacterial cellulose substrates in model animals as skin wound dressing or body implant further proves the high durability and low inflammatory response to the material over a period of 21 days, demonstrating beneficial effects of surface structure on skin regeneration.
Optical and thermal simulation chain for LED package
Venue: 2016 17th International Conference on Thermal, Mechanical and Multi Physics Simulation and Experiments in Microelectronics and Microsystems (EuroSimE)
Year: 2016

This paper presents a test case for coupling two physical aspects of an LED, optical and thermal, using specific simulation models coupled through an open source platform for distributed multi physics modelling. The glue code for coupling is written with Python programming language including routines to interface specific simulation models. This approach can also be used for any other software. The main optical simulations are performed with an open source ray tracer software and the main thermal simulations are performed with Comsol Multiphysics. We show how to connect a Mie theory based scattering calculator with the ray tracer. Simulation results are compared to measured samples. The total radiant power emitted by the modelled LED is shown to be up to 3% consistent with the measurements.
Integrating Optical Character Recognition and Machine Translation of Historical Documents
Venue: LT4DH@COLING
Year: 2016

Machine Translation (MT) plays a critical role in expanding capacity in the translation industry. However, many valuable documents, including digital documents, are encoded in non accessible formats for machine processing (e.g. Historical or Legal documents) Such documents must be passed through a process of Optical Character Recognition (OCR) to render the text suitable for MT. No matter how good the OCR is, this process introduces recognition errors, which often renders MT ineffective. In this paper, we propose a new OCR to MT framework based on adding a new OCR error correction module to enhance the overall quality of translation. Experimentation shows that our new system correction based on the combination of Language Modeling and Translation methods outperforms the baseline system by nearly 30% relative improvement.
Confirmation of WASP 107b's Extended Helium Atmosphere with Keck II/NIRSPEC
Year: 2020

We present the detection of helium in the extended atmosphere of the sub Saturn WASP 107b using high resolution $R \approx 25000$ near infrared spectra from Keck II/NIRSPEC. We find peak excess absorption of $7.26 \pm  (30$\sigma$ centered on the HeI triplet at 10833A. The amplitude and shape of the helium absorption profile is in excellent agreement with previous observations of escaping helium from this planet made by CARMENES and HST. This suggests there is no significant temporal variation in the signature of escaping helium from the planet over a two year baseline. This result demonstrates Keck II/NIRSPEC's ability to detect atmospheric escape in exoplanets, making it a useful instrument to further our understanding of the evaporation of exoplanetary atmospheres via ground based observations of HeI.
Sofosbuvir for previously untreated chronic hepatitis C infection.
Venue: The New England journal of medicine
Year: 2013

In phase 2 trials, the nucleotide polymerase inhibitor sofosbuvir was effective in previously untreated patients with chronic hepatitis C virus (HCV) genotype 1, 2, or 3 infection.  We conducted two phase 3 studies in previously untreated patients with HCV infection. In a single group, open label study, we administered a 12 week regimen of sofosbuvir plus peginterferon alfa 2a and ribavirin in 327 patients with HCV genotype 1, 4, 5, or 6 (of whom 98% had genotype 1 or 4) In a noninferiority trial, 499 patients with HCV genotype 2 or 3 infection were randomly assigned to receive sofosbuvir plus ribavirin for 12 weeks or peginterferon alfa 2a plus ribavirin for 24 weeks. In the two studies, the primary end point was a sustained virologic response at 12 weeks after the end of therapy.  In the single group study, a sustained virologic response was reported in 90% of patients (95% confidence interval, 87 to 93) In the noninferiority trial, a sustained response was reported in 67% of patients in both the sofosbuvir ribavirin group and the peginterferon ribavirin group. Response rates in the sofosbuvir ribavirin group were lower among patients with genotype 3 infection than among those with genotype 2 infection (56% vs. 97% Adverse events (including fatigue, headache, nausea, and neutropenia) were less common with sofosbuvir than with peginterferon.  In a single group study of sofosbuvir combined with peginterferon ribavirin, patients with predominantly genotype 1 or 4 HCV infection had a rate of sustained virologic response of 90% at 12 weeks. In a noninferiority trial, patients with genotype 2 or 3 infection who received either sofosbuvir or peginterferon with ribavirin had nearly identical rates of response (67% Adverse events were less frequent with sofosbuvir than with peginterferon.
Evaluation de la prise en charge medicale de l'insuffisance cardiaque a l'hopital national Blaise COMPAORE
Venue: Annales de Cardiologie et d'Angeiologie
Year: 2019

Resume But Le but de cette etude etait d'evaluer la qualite de la prise en charge medicale de l'insuffisance cardiaque a l'hopital national Blaise COMPAORE comparativement aux recommandations internationales. Patients et methodes C'est une etude retrospective realisee chez les patients consecutifs admis pour insuffisance cardiaque documentee echographiquement d'octobre 2012 a mars 2015 dans le service de medecine et specialites medicales de l'hopital national Blaise COMPAORE et ayant un suivi minimum de six semaines. L'analyse des donnees est faite par le logiciel SPSS version 20.0. Resultats Quatre vingt et quatre patients d'age moyen de 57,61 18,24 ans ont ete inclus. L'insuffisance cardiaque aigue representait 84,5 des cas avec fonction systolique du ventricule gauche alteree (77,4 Le taux de prescription des differents medicaments chez les insuffisants cardiaques tout type etait de 88,1 pour les diuretiques de l'anse 77,1 pour les inhibiteurs de l'enzyme de conversion de l'angiotensine/antagonistes des recepteurs de l'angiotensine II et 65,5 pour les betabloquants. Chez les patients avec dysfonction systolique ce taux etait de 84,6 pour l'association inhibiteurs de l'enzyme de conversion de l'angiotensine/antagonistes des recepteurs de l'angiotensine II et 75,4 pour les betabloquants. Le reentrainement a l'effort a concerne 10,7 des patients. Le taux de deces a ete de 16,7 et le taux de rehospitalisation de 16,7 Conclusion Le taux de prescription des medicaments majeurs de l'insuffisance cardiaque est satisfaisant. La readaptation cardiovasculaire doit etre developpee.
Polysuccinimide and its derivatives: Degradable and water soluble polymers (review)
Year: 2018

Interest for water soluble polymers which show biocompatibility and degradability is growing due to their potential applications in medical sciences. Polysuccinimide (PSI) commonly synthesized through thermal polymerization, is a polyimide precursor for the production of such biocompatible and degradable polymers namely polyaspartic acid and various polyaspartamides. Polyaspartic acid is usually obtained by hydrolysis of PSI while polyaspartamide is produced by ring opening of PSI using a nucleophilic reagent. The presence of amide linkages in these polymers gives them peptide like structures which is prone to hydrolysis and subsequent degradation. These derivatives could be potential substitutes for different polyamino acids in many medical applications. This review compiles the works carried out on developing polysuccinimide and its derivatives as well as the main synthetic routs and characterization methods.
The Rites of Passage Framework as a Matrix of Transgression Processes in the Life Course
Venue: Journal of adult development
Year: 2018

This work shows the contribution of concept of rites of passage and theory of liminality to the understanding of transformations in the course of a person's life. The structural functional analysis of empirical studies of physical changes, changing roles in society, and key changes in the area of mental and physical health conducted from the perspective of these theories has allowed to identify the three fundamental processes that govern the attainment of transformation and transgression into a new phase of life. The aim of this paper is to set out the processes identified in the course of functional structural analysis of chosen studies and they comprise: (1) preservation of the sequence of the life course; (2) liminality: deconstruction, integration, and transformation; and (3) performativity. These processes provide a structural framework for understanding life crises, thus facilitating their study as phases of dynamic transformations connected with the successive roles and tasks over the life course.
Entrepreneurial Education at the Tertiary Level in Nigeria Imperative for Poverty Reduction and Economic Development
Year: 2014

Globally, entrepreneurship is seen not only as the anti dote to the astronomically growing socio economic problem of unemployment, but particularly as the engine of economic growth and stability and by extension, the prosperity of nations. Accordingly, concerted efforts, backed by deliberate State policies and strategies, are normally geared towards its promotion and sustenance. The starting point has been recognized to be wholistic and integrated education and enlightening programmes/projects, such as the National Consortium on Entrepreneurship Education in the USA. Nigeria has not been left out of this global attention, as the National Universities' Commission, NUC, recently directed every tertiary institution in the Country to make entrepreneurial education an integral part of its curriculum. This paper examines, among others, the necessity, scope and challenges of this all important programme at the most critical level of education. A wholistic approach has been adopted, including a survey of relevant stakeholders, notably students at the tertiary level of education in Nigeria, with thought provoking positions/findings upon which appropriate strategies and approaches have been contributed for not only the success of the programme, but most important for the much desired economic transformation revolutionized by entrepreneurial spirit.
A Capability Development Model for Assessing and Improving Distributed Infrastructures and their Services.
Year: 2016

As part of the CESSDA SaW (Strengthening and Widening) project a capability development model (CDM) was instigated to aid current and aspiring service providers to participate in CESSDA to their maximum ability: some partners have a long history and have set high ambitions and funding, whereas other partners are in the process of setting up their archives, sometimes with limited funding. Rather than setting fixed requirements for each service and provider within an infrastructure, the CDM can be used to define both the organisation's desired state and provide effective guidance on how to improve services that form part of the infrastructure gradually, initially to the minimal and then, to the desired state for the service provider. The CDM can be adapted to other infrastructural contexts in the social sciences and humanities. In this this presentation we will show the model, discuss how it can be used to identify gaps in service provision as well as managed improvements. Furthermore, we will consider how it could be adapted for use in other distributed infrastructures, or used in tandem with other maturity models (such as CESSDA's software maturity matrix) plus future developments of the model.
Improving student learning performance in a virtual hands on lab system in cybersecurity education
Venue: 2018 IEEE Frontiers in Education Conference (FIE)
Year: 2018

This Research Work in Progress paper presents a study on improving student learning performance in a virtual hands on lab system in cybersecurity education. As the demand for cybersecurity trained professionals rapidly increasing, virtual hands on lab systems have been introduced into cybersecurity education as a tool to enhance students' learning. To improve learning in a virtual hands on lab system, instructors need to understand: what learning activities are associated with students' learning performance in this system? What relationship exists between different learning activities? What instructors can do to improve learning outcomes in this system? However, few of these questions has been studied for using virtual hands on lab in cybersecurity education. In this research, we present our recent findings by identifying that two learning activities are positively associated with students' learning performance. Notably, the learning activity of reading lab materials (p 0:01) plays a more significant role in hands on learning than the learning activity of working on lab tasks (p 0:05) in cybersecurity education.In addition, a student, who spends longer time on reading lab materials, may work longer time on lab tasks (p 0:01)
[Current status of dental English education in China]
Venue: Shanghai kou qiang yi xue Shanghai journal of stomatology
Year: 2016

The teaching of dental English for undergraduate students plays an important role in dental education. Most dental schools or colleges have set up the course of dental English education in China. However, this course lacks of a unified educational plans, contents and goals based on actual situation of dental students, which does not fully achieve the teaching purpose. This study was aimed to explore the developmental direction of the course of dental English education through comparison among different dental schools or colleges in China, in order to find out the teaching mode of dental English education, and promote the teaching effect and cultivation of international dental talents.