nils-herrmann/clean_scirepeval huggingface dataset:
Propolis based niosomes as oromuco adhesive films: A randomized clinical trial of a therapeutic drug delivery platform for the treatment of oral recurrent aphthous ulcers
Venue: Scientific Reports
Year: 2018

Oromuco adhesive films for buccal delivery of Propolis extract (PPE) entrapped in niosomes, were prepared to treat oral recurrent aphthous ulcer (RAU) PPE was investigated for antimicrobial compounds. Niosomes composed of span60 and cholesterol were evaluated for particles size, polydispersity index (PDI) zeta potential, entrapment efficiency and in vitro release. The formed oromuco adhesive films containing niosomal PPE were evaluated for swelling, mucoadhesion and elasticity. 24 patients suffering from RAU were divided equally into medicated and placebo groups and participated in this study to examine the onset of ulcer size reduction, complete healing and pain relief. Ultra performance liquid chromatography high resolution mass spectrometry revealed the presence of pinocembrin, pinobanksin, chrysin and galangin as antimicrobial flavonoids with total content of 158.7 0.15 ug quercetin equivalents and phenolic content of 180.8 0.11 ug gallic acid equivalents/mg. Multilamellar niosomes of 176 333 nm displayed entrapment efficiency of 91 0.48% PDI of 0.676 and zeta potential of 4.99. In vitro release after 8 h from niosomal dispersion and films were 64.05% and 29.09 0.13% respectively. Clinical results revealed duration of film adherence from 2 4 h in the two groups. The onset of ulcer size reduction in medicated group was attained within second and third day, complete healing was achieved within first 10 days of treatment and pain relief lasted for more than 4 5 h, in contrast to the placebo group. This oromuco adhesive films which offer controlled and targeting drug delivery can be proposed as a new therapeutic strategy in the treatment of oral recurrent aphthous ulcer.
NGOs' HIV/AIDS Discourse on Social Media and Websites: Technology Affordances and Strategic Communication Across Media Platforms
Year: 2019

Nongovernmental organizations (NGOs) play a pivotal role in combating HIV/AIDS. Yet research on the social construction of HIV/AIDS has investigated the discourse of the government, media, and the public but not NGOs. Drawing on the technology affordance framework, this study examines NGOs' discourse on social media and websites in China to understand how they communicate HIV/AIDS issues. Results of semantic network analysis reveal overlapping themes about HIV/AIDS across social media and websites, including promoting public policy, public education, and social support. Additionally, NGOs leverage social media to mobilize various institutional and community health care resources and highlight their engagement with the government. This study underscores the pivotal role of NGOs in HIV/AIDS prevention, treatment, and destigmatization. It also advances the technology affordance literature by shedding light on the convergent yet distinct affordances of different digital media for strategic health communication and the constraints of the sociopolitical context on organizations' communicative practices.
Physical Activity Counseling in College Students
Year: 2018

Many college students are insufficiently physically active, and health care practitioner consultations represent an opportunity to provide at risk students with physical activity counseling (PAC) This study examined whether any demographic or physiological variables differentiated those who had received PAC and those who did not. An objective fitness assessment and survey collected data from college students concerning the following: demographics; body composition; aerobic fitness; cholesterol, lipid, and glucose levels; muscular endurance; physical activity (PA) levels; health care and PAC; PA information sources; and depression. Parametric and nonparametric techniques were used to examine differences between those who did and did not receive PAC, by location of counseling, and between those who did and did not report depressive symptoms. Rates of PAC were high, with only total cholesterol differentiating those who did and did not receive PAC. Study design prevented the determination of whether students or health care providers initiated PAC and what form of PAC was provided. Vigorous PA was significantly lower among those who reported mental health related symptoms. Findings suggest a lack of targeted PAC among the least active, least fit, or most overweight/obese. Further investigation is warranted on the use of PAC at campus health services. In particular, the initiation of PAC, the PAC techniques/strategies used by physicians, and the short and long term effectiveness of PAC on PA and associated health outcomes. Barriers to student health care center physicians providing PAC also require further investigation, as does the effectiveness of any PAC and any support provided by physical fitness professionals that students may be referred to in both the short and long term.
Evolving ICT and governance in organizational networks Conceptual and theoretical foundations
Venue: Electron. Mark.
Year: 2016

Both private and public sector organizations tend to participate in networks in order to gain access to knowledge, skills and resources of other organizations and to create synergies to achieve highly demanding and complex goals they cannot attain individually. The governance of these networks has been recognized as being an important variable influencing organizational network performance. This Special Issue aims to contribute to the investigation and understanding of the relationships between ICT and governance of organizational networks. This introductory paper provides the conceptual and theoretical background. The relationship between network governance and technology is bi directional; evolutions in ICT enable the development of new types of network collaborations and governance, whereas governance of collaboration networks is critical for the development of complex ICT infrastructures. We argue that network governance should be conceptualized as an evolving socio technical process shaped by actors and aimed at tackling complex and dynamic contemporary challenges.
Enhanced Wireless Hotspot Downlink Supporting IEEE802.11 and WCDMA
Venue: 2006 IEEE 17th International Symposium on Personal, Indoor and Mobile Radio Communications
Year: 2006

Dual mode handsets that support both cellular and wireless local area network (WLAN) interfaces have been recently introduced by manufacturers like Nokia. Wireless hotspots also better to be enhanced to support both these services. Simultaneous subcarrier multiplexed transmission of both WLAN and cellular radio signals over a single radio over fiber (ROF) link is possible for hotspot enhancement. However, link design in this multi system scenario is a complex task. There are number of quality measures such as signal to noise, distortion and interference ratios involved both in the optical link and in the air interface. These are functions of several parameters such as the fiber length, system bandwidth, modulation depth, radio cell size and relative RF power. The scenario is quite challenging when two RF systems are involved. In this paper we analyze such a dual system downlink and show how to decide the cumulative optical modulation index (mu) and the RF power ratio (T) that will yield the best performance for both systems
An eSport Research: Psychological Well Being Differences of Teenagers in Terms of Several Variables
Year: 2020

Teenagers who tend to have an esport career are steadily increased while esport is trending for more than a decade. As esport sector offers job opportunities and massive earnings, it is predictable that why teenagers desire to become a professional esport player or to work in esport sector. On the other hand, massive gameplay times may lead to psychological problems. As current employment and earnings effect mental health in several aspects, uncertainty of esport sector's effect is an enigma. The sample of this study consists of 368 participants from all over the world. Web based questionnaire and psychological well being scale was used to collect the data which had been collected via Steam Community and Facebook. In this study we compared psychological well beings of teenagers with aspect of their employment status and daily game play times. In accordance with the results, professional esport players have significantly lower psychological well being than other two working groups. Also group of two playing more than 6 hours per day have significantly lower psychological well being than the group of two playing less than 6 hours per day.
Manufacture of tumor and virus specific T lymphocytes for adoptive cell therapies
Venue: Cancer Gene Therapy
Year: 2015

Adoptive transfer of tumor infiltrating lymphocytes (TILs) and genetically engineered T lymphocytes expressing chimeric antigen receptors (CARs) or conventional alpha/beta T cell receptors (TCRs) collectively termed adoptive cell therapy (ACT) is an emerging novel strategy to treat cancer patients. Application of ACT has been constrained by the ability to isolate and expand functional tumor reactive T cells. The transition of ACT from a promising experimental regimen to an established standard of care treatment relies largely on the establishment of safe, efficient, robust and cost effective cell manufacturing protocols. The manufacture of cellular products under current good manufacturing practices (cGMPs) has a critical role in the process. Herein, we review current manufacturing methods for the large scale production of clinical grade TILs, virus specific and genetically modified CAR or TCR transduced T cells in the context of phase I/II clinical trials as well as the regulatory pathway to get these complex personalized cellular products to the clinic.
Automatic Discovery of Complementary Learning Resources
Venue: EC TEL
Year: 2011

Students in a learning experience can be seen as a community working simultaneously (and in some cases collaboratively) in a set of activities. During these working sessions, students carry out numerous actions that affect their learning. But those actions happening outside a class or the Learning Management System cannot be easily observed. This paper presents a technique to widen the observability of these actions. The set of documents browsed by the students in a course was recorded during a period of eight weeks. These documents are then processed and the set with highest similarity with the course notes are selected and recommended back to all the students. The main problem is that this user community visits thousands of documents and only a small percent of them are suitable for recommendation. Using a combination of lexican analysis and information retrieval techniques, a fully automatic procedure to analyze these documents, classify them and select the most relevant ones is presented. The approach has been validated with an empirical study in an undergraduate engineering course with more than one hundred students. The recommended resources were rated as "relevant to the course" by the seven instructors with teaching duties in the course.
The importance of carotid artery stiffness and increased intima media thickness in obese children.
Venue: South African medical journal Suid Afrikaanse tydskrif vir geneeskunde
Year: 2012

Atherosclerosis that starts in childhood invariably advances during adulthood.  We aimed to study the effect of obesity on main carotid artery intima media thickness and arterial stiffness.  A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (42 group 1) and normal (36 group 2) All the children were subjected to physical examination, routine biochemical and haematological analysis, carotid ultrasonography and echocardiographic measurements. A detailed medical history was obtained. Body mass index (BMI) was calculated by dividing participants' weight in kilograms by the square of their height in metres. Stiffness index b was calculated using blood pressure and diameter of the systolic and diastolic artery. Intima media thickness was also measured.  The mean age of the obese and normal (control) groups were 10.12+ 2.12 years and 9.78+ 1.78 years respectively. Weight, BMI, and systolic and and diastolic blood pressure values were significantly higher in the obese group (all p<0.001) In terms of arterial stiffness and carotid intima media thickness (CIMT) measurements, all parameters were higher in the obese group than the control (p<0.001) There was a relationship between the degree of obesity and CIMT or stiffness index b. In addition, dilatation and hypertrophy levels in the left ventricle were higher in obese children.  Obese children with risk factors for multiple atherosclerosis could have increased CIMT dimensions and consequently should be screened for these risks. Ultrasonographic CIMT and arterial stiffness measurements can detect vascular damage at an early stage of development in children with cardiovascular risk factors.
Pulse control of a delay HIV epidemic model with switching parameters
Venue: 2017 29th Chinese Control And Decision Conference (CCDC)
Year: 2017

This paper proposes a new delay HIV (Human Immunodeficiency Virus) epidemic model with switching parameters and pulse control. We investigate the global attractivity of infection free periodic solution and the persistence of the disease. Furthermore, two thresholds which govern the extinction and the persistence of the epidemic disease are derived. Numerical simulations are performed to illustrate the theoretical findings and the effects of control measures.
Research on Product Data Exchange Technology Based on XML Language and STEP Standard in Collaborative Design
Year: 2008

In Web based collaborative manufacturing environment,in order to solve the information exchange problem caused by heterogeneous CAD systems located in different places,and to realize collaborative design among cooperative members,there's in need to develop uniform product information integration specification.Based on the comparison of different exchange technologies,the paper put forward a method by using STEP as neutral mechanism and applying XML as the carrier for product information model transmission through Internet.Regulations and methods for mapping from EXPRESS to XML were discussed in the paper.Research and exploration on XML/STEP based product data exchange,data sharing and information integration under Web based collaborative manufacturing environment were done in the paper.
Toxicity mechanisms of arsenic that are shared with neurodegenerative diseases and cognitive impairment: Role of oxidative stress and inflammatory responses.
Venue: Neurotoxicology
Year: 2016

Arsenic (As) is a worldwide naturally occurring metalloid. Human chronic exposure to inorganic As compounds (iAs) which are at the top of hazardous substances (ATSDR, 2013) is associated with different diseases including cancer and non cancerous diseases. The neurotoxic effects of iAs and its methylated metabolites have been demonstrated in exposed populations and experimental models. Impaired cognitive abilities have been described in children and adults chronically exposed to iAs through drinking water. Even though different association studies failed to demonstrate that As causes neurodegenerative diseases, several toxicity mechanisms of iAs parallel those mechanisms associated with neurodegeneration, including oxidative stress and inflammation, impaired protein degradation, autophagy, and intracellular accumulation, endoplasmic reticulum stress, and mitochondrial dysfunction. Additionally, different reports have shown that specifically in brain tissue, iAs and its metabolites induce hyper phosphorylation of the tau protein and over regulation of the amyloid precursor protein, impaired neurotransmitters synthesis and synaptic transmission, increased glutamate receptors activation, and decreased glutamate transporters expression. Interestingly, increased and sustained pro inflammatory responses mediated by cytokines and related factors, seems to be the triggering factor for all of such cellular pathological effects. Therefore, this review proposes that iAs associated cognitive impairment could be the result of the activation of pro inflammatory responses in the brain tissue, which also may favor neurodegeneration or increase the risk for neurodegenerative diseases in exposed human populations.
House Prices, Local Demand, and Retail Prices
Venue: Journal of Political Economy
Year: 2019

We document a causal response of local retail prices to changes in local house prices, with elasticities of 15 20 percent across housing cycles. These price responses are largest in zip codes with many homeowners and are driven by changes in markups rather than local costs. We argue that markups rise with house prices because greater housing wealth reduces homeowners' demand elasticity, and firms raise markups in response. Shopping data confirm that house price changes affect the price sensitivity of homeowners, but not that of renters. Our evidence suggests a new source of business cycle markup variation.
Medication errors among Iranian emergency nurses: A systematic review
Venue: Epidemiology and health
Year: 2020

Medication errors (MEs) made by nurses are the most common errors in emergency departments (EDs) Identifying the factors responsible for MEs is crucial in designing optimal strategies for reducing such occurrences. The present study aimed to review the literature describing the prevalence and factors affecting MEs among emergency ward nurses in Iran.  We searched electronic databases, including the Scientific Information Database, PubMed, Cochrane Library, Web of Science, Scopus, and Google Scholar, for scientific studies conducted among emergency ward nurses in Iran. The studies were restricted to full text, peer reviewed studies published from inception to December 2019, in the Persian and English languages, that evaluated MEs among emergency ward nurses in Iran.  Eight studies met the inclusion criteria. Most of the nurses (58.9% had committed MEs only once. The overall mean rate of MEs was 46.2% and errors made during drug administration accounted for 41.7% of MEs. The most common type of administration error was drug omission (17.8% followed by administering drugs at the wrong time (17.5% and at an incorrect dosage (10.6% The lack of an adequate nursing workforce during shifts and improper nurse patient ratios were the most critical factors affecting the occurrence of MEs by nurses.  Despite the increased attention on patient safety in Iran, MEs by nurses remain a significant concern in EDs. Therefore, nurse managers and policy makers must take adequate measures to reduce the incidence of MEs and their potential negative consequences.
Steps for encouraging early independent writing: A language perspective on whole class literacy learning inclusive of EAL/D learners
Year: 2013

In the Language Perspectives team, we take the view that students' proficiency in Standard Australian English (SAE) is a fundamental consideration in classroom approaches to literacy teaching. Yet often language considerations are not prominent in education documents, teacher education or teaching resources. Unsurprisingly then, in classroom contexts there is often little reference to whether students' language resources in SAE match those of the teacher or the curriculum expectations. Sometimes, language is just obscured by or confused with literacy. (McIntosh et al. 2011)
Suppression of acoustic emission during superelastic tensile cycling of polycrystalline Ni50.4Ti49.6
Year: 2020

We investigate acoustic emission (AE) that arises during the martensitic transition in a polycrystalline specimen of the prototypical superelastic/elastocaloric alloy Ni$_{50.4}$Ti$_{49.6} (at. driven using tensile strain. We use two independent AE sensors in order to locate AE events, and focus on contributions to the AE that arise away from the grips of the mechanical testing machine. Significant AE activity is present during the first mechanical loading primarily due to nucleation and growth of wide Luders like bands during the forward martensitic transition (imaged using visible light and infrared (IR) radiation) that lead to persistent changes in intergranular interactions. AE activity is suppressed during the subsequent reverse martensitic transition on unloading, and in successive loading/unloading cycles, for which the Luders like bands narrow and modify intergranular interactions to much less extent. After the first loading, we find that the AE activity associated with the martensitic transition is weak, and we suggest that this is because the elastic anisotropy and strain incompatibility in Ni Ti are low. We also find that the AE activity becomes weaker on mechanically cycling due to increased retained martensite.
Static Load Test of Pre stressed Concrete Cable Stayed Bridge with Single Tower and Single Cable Plane
Year: 2012

Based on static load test result of pre stressed concrete cable stayed bridge with single tower and single cable plane and combined with theoretical calculation result,characteristics of cable stayed bridge like cable force change rules,strength and rigidity under different working conditions of load test are studied through analyzing significant test data of control section under working condition of static load test,such as cable force increment,off normal of main tower top,deflection of main beam and cross section stress.
Visual loss without headache in children with pseudotumor cerebri and growth hormone treatment.
Venue: Neuropediatrics
Year: 2013

We report on two prepubescent girls with visual loss due to idiopathic intracranial hypertension (IIH) or pseudotumor cerebri, both treated with recombinant human growth hormone for growth failure. The interval from starting hormone therapy to diagnosis of IIH was 3 and 18 months, respectively. Both girls did not complain of headache and nausea. They were neither obese nor did they suffer from renal insufficiency. In both patients, we observed bilateral optic disc edema with visual loss and elevated cerebrospinal fluid (CSF) pressures. Other causes of IIH were excluded with neuroimaging and CSF examination. Cessation of drug administration is often sufficient for symptom resolution in cases of hormone therapy associated IIH. However, visual field defects in one girl remained unchanged during follow up of 8 months. In children with IIH, the spectrum of neurologic and visual manifestations might be variable and unspecific. Diagnosis and management of IIH can be difficult in the absence of headache. Blurred or double vision due to cranial nerve palsy might be the only symptom rather than complaints about reduced visual acuity. Therefore, regular clinical monitoring of visual function and fundus appearance is essential for early diagnosis, efficient management, and improvement of visual outcome in children receiving recombinant human growth hormone.