nils-herrmann/clean_scirepeval huggingface dataset:
Extrusion processing of cereal grains, tubers, and seeds
Year: 2020

Cereal grains are commonly used ingredients in the extruded food products that are found in the market today. Other commonly used ingredients include tubers, such as potato, tapioca, and pulses, such as dry peas, lentils, chickpeas, and dry beans. Cereal grains, such as corn, wheat, rice, and others, contain a significant amount of starch, which contributes to the phenomenon of direct expansion during extrusion. Most often, these ingredients are used in their refined forms. The insoluble fiber component present in the outer seed cover, such as the bran, hull, husk, and others, is removed during the milling process to obtain the refined flours. In recent years, there has been a significant push in the utilization of the ancient grains, pseudo grains, pulses, and others that are considered as healthier ingredients. There has also been an effort to utilize the whole grain flours instead of the refined flours. This chapter provides a broad overview of the different cereal grains and seeds and their performance in extrusion processing for the development of direct expanded extruded food products.
Preventing bacterial infections with pilus based vaccines: the group B streptococcus paradigm.
Venue: The Journal of infectious diseases
Year: 2009

We recently described the presence of 3 pilus variants in the human pathogen group B streptococcus (GBS; also known as Streptococcus agalactiae) each encoded by a distinct pathogenicity island, as well as the ability of pilus components to elicit protection in mice against homologous challenge. To determine whether a vaccine containing a combination of proteins from the 3 pilus types could provide broad protection, we analyzed pili distribution and conservation in 289 clinical isolates. We found that pilus sequences in each island are conserved, all strains carried at least 1 of the 3 islands, and a combination of the 3 pilus components conferred protection against all tested GBS challenge strains. These data are the first to indicate that a vaccine exclusively constituted by pilus components can be effective in preventing infections caused by GBS, and they pave the way for the use of a similar approach against other pathogenic streptococci.
Goal contents as predictors of academic cheating in college students
Venue: Ethics Behavior
Year: 2019

The current study examined the longitudinal relationships between goal contents and academic cheating (serious versus minor cheating) among representative college students. Based on the framework of goal contents theory within self determination theory, wealth, fame, affiliation, self growth, social concern, and leisure goals were tested as predictive factors of two types of academic cheating. Participants were 2,360 representative college students from the Korean Education Longitudinal Study majoring in business, humanities, social sciences, engineering, education, arts, and medicine. They answered survey questionnaires twice at 1 year intervals. Hierarchical regression analysis found that self growth negatively predicted serious as well as minor cheating, and the wealth goal was positively correlated with minor cheating after controlling for previous cheating behaviors and gender. The results support goal contents theory and show that classifying academic cheating by severity permits a deeper understanding of students' academic cheating. Educators and practitioners seeking to encourage students' ethical behavior should pay closer attention to the goal contents they pursue to provide appropriate guidelines.
Mapeamento de risco: analise situacional da Biblioteca Central da Universidade Federal da Paraiba
Year: 2019

Este estudo propoe discutir algumas causas e resultados dos riscos de acidentes de trabalho, bem como identificar a percepcao dos Gestores da Biblioteca Central do Campus I da Universidade Federal da Paraiba quanto a esses riscos em seu local de trabalho, colocados graficamente atraves do mapeamento de riscos sugeridos pela legislacao vigente. A pesquisa desenvolvida pode ser caracterizada pela sua tipologia como analitica, e para tanto, foram coletados dados a partir de bibliografias referentes a normas e leis de seguranca de trabalho, tendo como fontes o Ministerio do Trabalho, Ministerio da Saude e Ministerio da Previdencia e Assistencia Social, e estudiosos do tema. Foram tambem aplicadas entrevistas por meio de questionarios, aos gestores da Biblioteca avaliada. Identifica se a partir dos resultados obtidos que, por parte dos gestores ainda faltam maiores esclarecimentos em relacao ao tema, e principalmente a questao da cultura da prevencao. Verifica se ainda que, as causas dos acidentes encontrados, sao diversas: o desconhecimento e/ou avaliacao ineficaz do risco, baixo investimento de prevencao, ausencia de treinamento e falta ou nao uso dos EPI (Equipamentos de Protecao Individual) e falhas estruturais do predio. E evidente que, o processo de seguranca na biblioteca avaliada, deve partir desde o planejamento ate a operacionalizacao de suas atividades, bem como da instauracao de Programas e Comissoes, direcionados a seguranca, conforme a Legislacao vigente. Com isso, a conscientizacao a respeito das praticas de seguranca por parte de todos os componentes da organizacao, deve ser preconizada.
An Efficient Biometric Multimodal Face, Iris and Finger Fake Detection using an Adaptive Neuro Fuzzy Inference System (ANFIS)
Year: 2014

The face, iris and finger print are among the most promising biometric authentication that can precisely identify and analysis a person as their unique textures can be quickly extracted during the recognition process. This biometric detection and authentication often deals with non ideal scenarios such as blurred images, off angles, reflections, expression changes. These precincts imposed by uni modal biometrics can be pound by incorporating multimodal biometrics. for this reason, in this paper, we present a new Effective fake detection method that can be used in multiple biometric systems to detect different types of fake access attempts. An important feature and objective of the proposed system is to enhance the image quality and very low degree of complexity for security of biometric recognition frameworks. For the preprocessing we used score level approach Median filter with canny edge detection and Hough transform with Anisotropic Gaussian Filter. For the Feature Extraction we have used Gabor filter. The classification is done by ANFIS which is an efficient classification. The performance of the proposed approach is validated and is efficient.
Dabrafenib; Preclinical Characterization, Increased Efficacy when Combined with Trametinib, while BRAF/MEK Tool Combination Reduced Skin Lesions
Venue: PloS one
Year: 2013

Mitogen Activated Protein Kinase (MAPK) pathway activation has been implicated in many types of human cancer. BRAF mutations that constitutively activate MAPK signalling and bypass the need for upstream stimuli occur with high prevalence in melanoma, colorectal carcinoma, ovarian cancer, papillary thyroid carcinoma, and cholangiocarcinoma. In this report we characterize the novel, potent, and selective BRAF inhibitor, dabrafenib (GSK2118436) Cellular inhibition of BRAFV600E kinase activity by dabrafenib resulted in decreased MEK and ERK phosphorylation and inhibition of cell proliferation through an initial G1 cell cycle arrest, followed by cell death. In a BRAFV600E containing xenograft model of human melanoma, orally administered dabrafenib inhibited ERK activation, downregulated Ki67, and upregulated p27, leading to tumor growth inhibition. However, as reported for other BRAF inhibitors, dabrafenib also induced MAPK pathway activation in wild type BRAF cells through CRAF (RAF1) signalling, potentially explaining the squamous cell carcinomas and keratoacanthomas arising in patients treated with BRAF inhibitors. In addressing this issue, we showed that concomitant administration of BRAF and MEK inhibitors abrogated paradoxical BRAF inhibitor induced MAPK signalling in cells, reduced the occurrence of skin lesions in rats, and enhanced the inhibition of human tumor xenograft growth in mouse models. Taken together, our findings offer preclinical proof of concept for dabrafenib as a specific and highly efficacious BRAF inhibitor and provide evidence for its potential clinical benefits when used in combination with a MEK inhibitor.
Neuroplasticity in the phonological system: The PMN and the N400 as markers for the perception of non native phonemic contrasts by late second language learners
Venue: Neuropsychologia
Year: 2021

Second language (L2) learners frequently encounter persistent difficulty in perceiving certain non native sound contrasts, i.e. a phenomenon called "phonological deafness" However, if extensive L2 experience leads to neuroplastic changes in the phonological system, then the capacity to discriminate non native phonemic contrasts should progressively improve. Such perceptual changes should be attested by modifications at the neurophysiological level. We designed an EEG experiment in which the listeners' perceptual capacities to discriminate second language phonemic contrasts influence the processing of lexical semantic violations. Semantic congruency of critical words in a sentence context was driven by a phonemic contrast that was unique to the L2, English (e.g./I/ /i: ship sheep) Twenty eight young adult native speakers of French with intermediate proficiency in English listened to sentences that contained either a semantically congruent or incongruent critical word (e.g. The anchor of theship/*sheepwas let down) while EEG was recorded. Three ERP effects were found to relate to increasing L2 proficiency: (1) a left frontal auditory N100 effect, (2) a smaller fronto central phonological mismatch negativity (PMN) effect and (3) a semantic N400 effect. No effect of proficiency was found on oscillatory markers. The current findings suggest that neuronal plasticity in the human brain allows for the late acquisition of even hard wired linguistic features such as the discrimination of phonemic contrasts in a second language. This is the first time that behavioral and neurophysiological evidence for the critical role of neural plasticity underlying L2 phonological processing and its interdependence with semantic processing has been provided. Our data strongly support the idea that pieces of information from different levels of linguistic processing (e.g. phonological, semantic) strongly interact and influence each other during online language processing.
Feedback noncausal model predictive control of wave energy converters
Venue: Control Engineering Practice
Year: 2019

In this paper, a novel feedback noncausal model predictive control (MPC) strategy for sea wave energy converters (WECs) is proposed, where the wave prediction information can be explicitly incorporated into the MPC strategy to improve the WEC control performance. The main novelties of the MPC strategy proposed in this paper include: (i) the recursive feasibility and robust constraints satisfaction are guaranteed without a significant increase in the computational burden; (ii) the information of short term wave prediction is incorporated into the feedback noncausal MPC method to maximise the potential energy output; (iii) the sea condition for the WEC to safely operate in can be explicitly calculated. The proposed feedback noncausal MPC algorithm can also be extended to a wide class of control design problems, especially to the energy maximisation problems with constraints to be satisfied and subject to persistent but predictable disturbances. Numerical simulations are provided to show the efficacy of the proposed feedback noncausal MPC.
Cipralphelin, a new anti oxidative N cinnamoyl tripeptide produced by the deep sea derived fungal strain Penicillium brevicompactum FKJ 0123
Venue: The Journal of Antibiotics
Year: 2019

A new N cinnamoyl tripeptide, designated cipralphelin (1) was isolated from a cultured broth of Penicillium brevicompactum FKJ 0123 by physicochemical (PC) screening. Compound 1 was purified by silica gel and ODS column chromatography followed by preparative HPLC. The structure of 1 was determined as N cinnamoyl prolyl alanyl phenylalanine methyl ester by nuclear magnetic resonance and mass spectrometry analyses. The absolute configurations of three amino acids were determined by an advanced Marfey's method applied to the hydrolysate of 1. Compound 1 was evaluated for its cytotoxicity, anti microbial activity, and ability to scavenge or quench reactive oxygen species (ROS) such as superoxide anion radicals, hydroxy radicals, and singlet oxygen. Compound 1 exhibited potent scavenging activity against hydroxy radicals.
Social media e sentiment analysis l'evoluzione dei fenomeni sociali attraverso la rete
Year: 2014

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Cyber Threats Facing Autonomous and Connected Vehicles: Future Challenges
Venue: IEEE Transactions on Intelligent Transportation Systems
Year: 2017

Vehicles are currently being developed and sold with increasing levels of connectivity and automation. As with all networked computing devices, increased connectivity often results in a heightened risk of a cyber security attack. Furthermore, increased automation exacerbates any risk by increasing the opportunities for the adversary to implement a successful attack. In this paper, a large volume of publicly accessible literature is reviewed and compartmentalized based on the vulnerabilities identified and mitigation techniques developed. This review highlighted that the majority of studies are reactive and vulnerabilities are often discovered by friendly adversaries (white hat hackers) Many gaps in the knowledge base were identified. Priority should be given to address these knowledge gaps to minimize future cyber security risks in the connected and autonomous vehicle sector.
It Only Affects Me: Pharmaceutical Regulation and Harm to Others
Venue: HEC forum an interdisciplinary journal on hospitals' ethical and legal issues
Year: 2020

In her Pharmaceutical Freedom, Jessica Flanigan argues that antibiotics can be regulated consistent with her otherwise largely deregulatory view with respect to pharmaceuticals and recreational drugs. I contend in this essay that the reasons for justifying antibiotic regulation are reasons that can be offered to justify the regulation of many other drugs, both pharmaceutical and recreational. After laying out the specifics of Flanigan's view, I suggest that it is amenable to the regulation of drugs like varenicline. Though such drugs can legitimately improve the quality of a patient's life by helping them quit smoking, they could be permissibly regulated if they expose others to impermissible risks. I then argue that recreational drugs like alcohol could be regulated using the same reasoning. In the penultimate section of this essay, I anticipate objections that one might have to my extension of arguments favoring antibiotic regulation to drugs correlated with aggression. Flanigan might find my extrapolation of her view as entirely plausible and accept that her view is relatively friendly to these regulations, or she might reconsider her antibiotic caveat if these regulations are overly paternalistic on her understanding. I conclude by briefly considering the benefits and drawbacks of adopting each view.
Entropy KEMIRA Approach for MCDM Problem Solution in Human Resources Selection Task
Venue: Int. J. Inf. Technol. Decis. Mak.
Year: 2017

Entropy KEMIRA approach is proposed for criteria ranking and weights determining when solving Multiple Criteria Decision Making (MCDM) problem in human resources selection task. For the first time the method is applied in the case of three groups of criteria. Weights are calculated by solving optimization problem of maximizing the number of elements, which are "best" according to all three criteria, and minimizing the number of "doubtful" elements. The algorithm of problem solution is presented in the paper. The numerical experiment with three groups of evaluation criteria describing 11 life goals was accomplished.
Testing environmental Kuznets curve hypothesis in G7 countries: the role of renewable energy consumption and trade
Venue: Environmental Science and Pollution Research
Year: 2018

This study has been conducted to examine the impact of trade, economic growth, and renewable energy on environmental degradation in G7 countries. The data consist of the years 1991 2016. We employed the panel unit root test and co integration test, along with cross sectional dependence and cross sectionally augmented IPS unit root test by Pesaran ( 2007) We also employed dynamic ordinary least squares, fully modified ordinary least squares, and fixed effect ordinary least squares regression. The result concluded that all the variables are co integrated in the long run and all the variables create a significant effect on CO2 emission. This study implies that economic growth and trade increases the CO2 emission in the long run whereas the renewable energy consumption reduces the CO2 emission in the long run. The result also provides support for the Environmental Kuznets curve hypothesis in G7 countries.
CubeQA Question Answering on RDF Data Cubes
Venue: SEMWEB
Year: 2016

Statistical data in the form of RDF Data Cubes is becoming increasingly valuable as it influences decisions in areas such as health care, policy and finance. While a growing amount is becoming freely available through the open data movement, this data is opaque to laypersons. Semantic Question Answering (SQA) technologies provide intuitive access via free form natural language queries but general SQA systems cannot process RDF Data Cubes. On the intersection between RDF Data Cubes and SQA, we create a new subfield of SQA, called RDCQA. We create an RDQCA benchmark as task 3 of the QALD 6 evaluation challenge, to stimulate further research and enable quantitative comparison between RDCQA systems. We design and evaluate the domain independent CubeQA algorithm, which is the first RDCQA system and achieves a global (F_1\ score of 0.43 on the QALD6T3 test benchmark, showing that RDCQA is feasible.
Image Deblurring Using Scale recurrent Network for Mobile Devices
Venue: 2019 International Conference on Advanced Computer Science and information Systems (ICACSIS)
Year: 2019

Image deblurring is a problem in computer vision that aims to restore blur images into sharp images. The blurring might be caused by the camera shaking or an object moving when the image is captured, resulting in an image with a non uniform blur in a dynamic scene. One recent approach to restoring images with non uniform blur is by using end to end deep neural networks. Continuing the deblur research using a scale recurrent network, we modify the neural network architecture to be lighter to run on mobile devices. The proposed method achieves PSNR of 29.55 and SSIM of 0.8873 in a 16.9 MB sized model. The inference process on a mobile device only requires 1 GB of memory with 8.2 seconds in latency for deblurring a single 1280x720 pixel image.
Letter to the Editor regarding: Negative pressure wound therapy Re: Wang X, Zhang Y, Han C: Topical negative pressure improves autograft take by altering nutrient diffusion: A hypothesis.
Year: 2014

I read the article of Wang et al.  entitled "Topical negative pressure improves autograft take by altering nutrient diffu sion: A hypothesis" with great interest. Negative pressure wound therapy (NPWT) is generally used in a two step surgi cal procedure to treat surgical site infections. At the time the wound is sterile and wound granulation has been initiated, the wound can be secondary surgically closed using different available techniques, such as direct sternal closure, pectora lis muscle flap, rectal muscle flap, omentum plasty or latissi mus dorsi plasty.Today, NPWT is also used to prevent surgical site infections after surgery, due to the unique positive applied mechanical forces as a permutation of Wolff's law. Additionally it is also used to support more superficial full thickness skin defects where mobilization of the surrounding tissue is not possible or limited and extensions are needed by different substitutes. The current study is important in patients who are treated for acute full thickness skin defects with this hypothesized one step closure method, using a commercial dermal substitute. The authors report that it takes approximately three weeks for these substitutes to become completely vascularized. Up till this time period, the functionality of the material is not com parable with native skin tissue, which forms a natural barri er against microbial invasion. The hypothesis of the authors was concentrated only on rapid balance of nutrient supply and angiogenesis due to NPWT, but by reading the literature care fully, NPWT seems to be even more innovative [2].Previous studies have shown that NPWT can significantly de crease the tissue bacterial count as early as four days after implementing this therapy compared with controls in a ran domized trial. Therefore NPWT is not only an active barrier for microbes to enter the skin, but also the number of microbes is actively reduced after starting this therapy. Furthermore the sub atmospheric pressure will prevent the progressive tissue damage of the surrounding tissue at the initial injury, start ing hours after insertion. Additionally wound oedema is re duced, as well as proteolytic enzymes and cytokines deriving from cell necrosis will be transported away from the granu lation tissue, which will improve wound healing. On the oth er hand it is also conceivable that supporting mediators for wound healing are transported away from the wound by in stalling NPWT. Further studies will be needed to identify and analyse these factors and evaluate potential possibilities to administer these mediators to the patients or better synthe tises them and apply them locally.It would be desirable to receive more experimental and clini cal data on this one step procedure, to better understand all single supportive developments to improved results of dermal substitutes to close theses full thickness skin defects.
Performance evaluation of controllable separate heat pipes
Year: 2016

A controllable separate heat pipe (CSHP) combined with cool storage can be an efficient and low cost solution to release the necessary cool power and to improve the precision in the temperature control of cool storage refrigerators powered by solar energy or electricity with time of use price policy. However, the precise temperature control performance of separate heat pipes under active control depends on system design and thus should be confirmed. In this study, a CSHP was developed and an active control method was achieved by interrupting its two phase natural circulation flow. A one dimensional steady state model was used to calculate the critical fill ratio, heat transfer rate, and average working temperature of CSHP. A series of experiments was conducted to analyze the start stop and heat transfer performances of CSHP at various R134a fill ratios and heat sink temperatures. Under different test conditions, the optimum working points were obtained through fitting. The most suitable control mode was determined and the start stop performance of CSHP was examined in detail. CSHP starts up quickly in approximately 15 seconds and the quickest stopping time of CSHP approximates to 80 seconds. Therefore, the performance of CSHP under active control can be applied to cool storage refrigerators.