nils-herrmann/clean_scirepeval huggingface dataset:
Antioxidant Activities of Dichrocephala integrifolia (Linn.f. O. Kuntze (Asteraceae) in a Mice Model of D Galactose Induced Oxidative Stress and Accelerated Aging
Year: 2017

Dichrocephala integrifolia is a plant widely used in folk medicine in Africa to treat central nervous diseases such as dementia. In the present study, we evaluated the effect of the leave's decoction of Dichrocephala integrifolia against D galactose induced neurotoxicity, oxidative stress and accelerated aging in mice. D galactose (100 mg/ kg sc) was chronically injected daily to mice during 42 consecutive days after pretreatment with distilled water (10 ml/kg) or the decoction of D. integrifolia (35; 87.5; 175 or 350 mg/kg p.o) or vitamin C (100 mg/kg p.o) Following behavioral tasks (Open Field, Elevated Plus Maze and Morris Water Maze) animals were sacrificed on day 43 and their brains were used to evaluate some biochemical parameters of oxidative stress (malondialdehyde, nitrite oxide and reduced glutathione) and for histopathological assessments. The results of this study showed that a pretreatment of animals with the decoction of D. integrifolia at the doses of 87.5 and 175 mg/kg significantly (p<0.05) reversed learning deficits, recall of memories and oxidative stress induced by D galactose. The decoction of D. integrifolia also prevented neurogeneration in the dentate gyrus induced by D galactose. These results indicated that D. integrifolia possesses neuroprotective effects against D galactose induced senescence, probably due to its antioxidant capacities and this can at least explain the wide use of this plant in traditional medicine in Cameroon in the prevention and treatment of dementia.  Alzheimer's disease; D. integrifolia: Dichrocephala. integrifolia; D gal: D galactose; MWM: Morris Water Maze; s.c. sub cutaneous; p.o :per os International Journal of Pharmacology, Phytochemistry and Ethnomedicine Submitted: 2017 03 30 ISSN: 2297 6922, Vol. 8, pp 41 53  2017 05 12 doi:10.18052/www.scipress.com/IJPPE.8.41 Accepted: 2017 06 01 2017 SciPress Ltd,  27 SciPress applies the CC BY 4.0 license to works we publish: https:/creativecommons.org/licenses/by/4.0/
Euro Who? Competition over the definition of Dersim's collective identity in Turkey's diasporas
Year: 2020

This article focuses on the construction and competition over Dersim identity that takes place in Dersim's diaspora, which also creates the necessity to critically engage with the concepts of Euro Turks and Euro Kurds. In doing so, it argues that while the activities of Dersimlis in the Dersim diaspora in Europe and in Turkey enable new identity claims, they also perpetuate a sense of belonging that builds upon ethnic, religious and/or linguistic domination. The first section broadly reviews the theoretical discussions on the complexity and fluidity of collective identities, diasporic movements, and the role the intelligentsia plays in the construction and competition over the definition of collective identities in diasporas. Building on this framework, the second section introduces the case of Dersim, the region and its history, and discusses the role Dersim diaspora and its intelligentsia play in (re)defining Dersim's collective memory and competing over the definition of Dersim's identity.
Impact de l'introduction d'options sur la dynamique et l'efficience informationnelle des marches supports Le cas des actions francaises cotees sur Euronext Liffe
Year: 2011

We investigate the impact of option listing on the underlying stock dynamics and the informational efficiency of the stock market, using data from the French Euronext Paris stock market about new option listing that occurred over the period 1996 2006. We take into account the implementation of a new trading system after the Euronext merger with the Liffe market in 2002 and the macroeconomic changes over the period.Considering different characteristics of stocks, we observe (i) no effect on both volatility and systematic risk measured by the beta, (ii) a negative price effect, although insignificant at the majority of times, (iii) a significant rise in the volume and, finally (iv) a significant decrease in the spread bid ask. By estimating a VAR model, we highlight a better adjustment to new information, observable jointly through contemporaneous and delayed relations between volume and volatility. However, when decomposing volatility into the contributions of informed and non informed agents, we cannot document any migration of informed traders to the underlying stock market after option listing. We confirm the absence of impact of option listing on the underlying stock pricing efficiency by examining the stock price duration dynamics, using a modified Log ACD model that accounts for liquidity captured by trade size.On the other hand, we show that in high volatility periods (low volatility periods) the option market plays a hedging role (speculation and/or arbitrage) The implementation of the new trading system after the Euronext merger with the Liffe market in 2002 appears to have no significant impact on the underlying stock. The global result about the absence impact of option listing is justified by the underlying stock's volatility driven trading. These strategies disturb the connection between option and underlying stock markets and the predictive power of option prices.
Investigation of coronary artery calcification and stenosis by coronary angiography CAG in haemodialysis patients
Year: 2006

consistently shown the benefits of cool dialysis in the prevention of IDH. Certainly, prescription of isothermic treatments controlled by the blood temperature feedback module (BTM) is not only appealing from a theoretical point of view, but was also found to be efficacious for the prevention of IDH in the randomized crossover trial by Maggiore et al.  However, a practical drawback for the use of BTM controlled dialysis is that this feature is only available on dialysis modules of a single manufacturer, whereas dialysate temperature can be easily adjusted on every dialysis module. Also, a feeling of coldness is not entirely prevented by isothermic dialysis sessions (5% of sessions)  which might be theoretically explained by an increase in the temperature setpoint during dialysis. In our dialysis centre, we have the practice of gradually reducing dialysate temperature from 36.5 C to a minimum of 35.5 C, depending on the haemodynamic response and subjective feelings of comfort in our patients. By this approach, together with strict volume control, aided by the use of vena cava echography, and adjustment of dialysis time if necessary, the incidence of IDH in our centre is well below 5% Treatments are well tolerated by the patients without shivering. Thus, we believe that in patients prone for IDH, a gradual lowering of dialysate temperature, which should be individualized according to the haemodynamic response and side effects in the patient, would appear a rational alternative when BTM controlled modules are not available.
Distributed Control for Uncertain Nonlinear Multiagent Systems Subject to Hybrid Faults
Year: 2020

This paper investigates a distributed consensus control problem for a class of uncertain nonlinear multiagent systems with hybrid faults. Most of the existing works about consensus control for multi agent systems solely consider either actuator faults or process faults. Different from the works, the more comprehensive hybrid faults are proposed which mainly focusing on both process and actuator faults occur simultaneously. For the nonlinear multiagent systems with uncertainties, we propose a less conservative consensus strategy which relax the conservative condition on nonlinear terms. Subsequently, the novel distributed consensus strategy is proposed with the help of backstepping design method. Based on the Lyapunov stability theory, it is proved strictly that the proposed controllers make the followers reach an agreement on certain quantity of common interest. Finally, a simulation example is given to verify the effectiveness of the theoretical result.
Semantic Classification of Pedestrian Traffic Scenarios for the Validation of Automated Driving
Venue: 2019 IEEE Intelligent Transportation Systems Conference (ITSC)
Year: 2019

This paper proposes a concept for the semantic classification of pedestrian traffic scenarios to estimate the test coverage during the validation of automated driving systems for urban environments. A model is introduced to describe pedestrian behavior as a combination of geometric data of their trajectory and maneuvers in relation to the surrounding infrastructure. The presented concept is applied and evaluated on an initial dataset of recorded measurement data to monitor the achieved coverage of pedestrian behavior during the test drives. Furthermore, the benefits and challenges of the approach are discussed. The methodology can help to detect semantic redundancy in a given scenario database and thereby improve the efficiency of the overall testing process. Moreover, common traffic scenarios can be identified, which makes it possible to focus real world test drives on these, while more infrequent scenarios are covered in simulations.
Out of the Darkness: Identifying Solutions for the Catholic Diocese of Dallas Amidst Child Sexual Abuse by Clergy
Year: 2020

Based on a lack of reporting allegations to law enforcement, the concealment of documents pertaining to allegations, the continued service of clergy accused of child sexual abuse, and the poor treatment of survivors, the Catholic Diocese of Dallas has demonstrated an inability to internally handle allegations of child sexual abuse by clergy. The main objective of this research is to identify solutions to the problems that plague the Catholic Diocese of Dallas and their current allegation review protocols. Therefore, the research question is: What are the current protocols used by the Catholic Diocese of Dallas to review allegations of child sexual abuse by clergy, where are these protocols failing, and how can these protocols be improved? Using interviews with subject matter experts, analysis of primary source documents produced by the Dallas Police Department, and examination of relevant Catholic Canon Laws, a comprehensive list of recommendations for individuals, Bishop Edward Burns, the Texas Legislature, The Texas Department of Public Safety, and Vatican level officials influencing Canon Law was developed. Each of these recommendations is intended to improve the allegation review process in the Catholic Diocese of Dallas and raise awareness about its current flaws.
Customer Churn Analysis in Banking Sector
Year: 2020

The role of ICT in the banking sector is a crucial part of the development of nations. The development of the banking sector mostly depends on its valuable customers. So, customer churn analysis is needed to determine customers whether they are at risk of leaving or worth retaining. From organizational point of view, gaining new customers is usually more difficult or more expensive than retaining existing customers. So, customer churn prediction has been popular in the banking industry. By reducing customer churn or attrition, the commercial banks gain not only more profits but also enhancing core competitiveness among the competitors. Although many researchers proposed many single prediction models and some hybrid model, but accuracy is still weak and computation time of some algorithms is still increased. In this research, churn prediction model of classifying bank customer is built by using the hybrid model of k means and Support Vector Machine data mining methods on bank customer churn dataset to overcome the instability and limitations of single prediction model and predict churn trend of high value users. Keywordschurn prediction, data mining, k means, Support Vector Machine
Goodness of fit tests for functional form of Linear Mixed effects Models
Year: 2019

Linear mixed effects models (LMMs) are a popular and powerful tool for analyzing clustered or repeated observations for numeric outcomes. LMMs consist of a fixed and a random component, specified in the model through their respective design matrices. Checking if the two design matrices are correctly specified is crucial since mis specifying them can affect the validity and efficiency of the analysis. We show how to use random processes defined as cumulative sums of appropriately ordered model's residuals to test if the functional form of the fitted LMM is correctly specified. We show how these processes can be used to test goodness of fit of the functional form of the entire model, or only its fixed and/or random component. Inspecting plots of the proposed processes is shown to be highly informative about the potential mis specification of the functional form of the model, providing clues for potential improvement of the model's fit. We show how the visual inspection can be objectified by using a novel procedure for estimating $p$ values which can be based on sign flipping/bootstrap or simulations and show its validity by using theoretical results and a large Monte Carlo simulation study. The proposed methodology can be used with LMMs with multi level or crossed random effects. and could also be extended to generalized LMMs.
A review of the Guadalupian (middle Permian) global tetrapod fossil record
Year: 2017

Until recently, the Guadalupian (middle Permian) tetrapod fossil record was known almost exclusively from the Karoo Basin of South Africa and the Cis Urals region of Russia, limiting progress towards understanding global middle Permian tetrapod biogeography. Recent work has shed light on several new or under explored Guadalupian tetrapod bearing basins, and we review and synthesize these findings here. We also review changes to the international and Russian Guadalupian time scales and present updated biostratigraphic correlations for all of the basins discussed. In general, there are few tetrapod genera or species shared between mid Permian basins, a pattern starkly different from the generic cosmopolitanism seen during Lopingian (late Permian) times. The Parana Basin of Brazil has produced a unique fauna that combines typical South African and Russian clades, suggesting a pathway for faunal interchange between the northern and southern portions of Pangea. The Dashankou fauna of China yields basal therapsids that suggest a northern Pangean origin for this clade. The Sundyr Assemblage of Russia preserves a latest Guadalupian fauna that seems to illustrate patterns of faunal turnover across the Guadalupian Lopingian boundary. Continued field work in the lesser known mid Permian strata will facilitate testing hypotheses about the transition between early and middle Permian faunas, the end Guadalupian extinction event, Pangean tetrapod biogeography, and the origins of widespread late Permian clades.
Dynamic vehicle routing problem considering simultaneous dual services in the last mile delivery
Venue: Kybernetes
Year: 2020

This paper aims to study the vehicle routing problem with dynamic customers considering dual service (including home delivery [HD] and customer pickup [CP] in the last mile delivery in which three decisions have to be made: determine routes that lie along the HD points and CP facilities; optimize routes in real time, which mode is better between simultaneous dual service (SDS, HD points and CP facilities are served simultaneously by the same vehicle) and respective dual service (RDS, HD points and CP facilities are served by different vehicles)  This paper establishes a mixed integer linear programing model for the dynamic vehicle routing problem considering simultaneous dual services (DVRP SDS) To increase the practical usefulness and solve large instances, the authors designed a two phase matheuristic including construction improvement heuristics to solve the deterministic model and dynamic programing to adjust routes to dynamic customers.  The computational experiments show that the CP facilities offer greater flexibility for adjusting routes to dynamic customers and that the SDS delivery system outperforms the RDS delivery system in terms of cost and number of vehicles used.  The results provide managerial insights for express enterprises from the perspective of operation research to make decisions.  This paper is among the first papers to study the DVRP SDS. Moreover, this paper guides the managers to select better delivery mode in the last mile delivery.
Estudo de condicoes de fermentacao alcoolica e acetica utilizando subproduto lacteo e diferentes leveduras
Year: 2017

A industria lactea produz diariamente altos volumes de efluentes. Um dos subprodutos e o permeado de soro de queijo, que apresenta elevada carga organica, devido seu alto teor de lactose e sais minerais. No intuito de aplicar residuos industriais e minimizar os impactos ambientais provocados por ele, busca se por meio da biotecnologia obter novos produtos empregando estes subprodutos. Nessa perspectiva, o objetivo deste trabalho foi produzir vinagre (fermentado acetico) utilizando as leveduras Saccharomyces boulardii e Kluyveromyces marxianus na etapa de fermentacao etanolica, seguida de fermentacao acetica pelas bacterias aceticas Acetobacter aceti (cepa pura) e "mae do vinagre" (cepa mista) A partir do permeado de soro de queijo foi aplicado um delineamento experimental fatorial 23 para cada levedura, para avaliar a producao de etanol. Com a melhor condicao de formacao de etanol para as leveduras, realizou se 12 ensaios aceticos com as duas bacterias aceticas pelos Metodos: Orleans, Orleans Modificado com adicao de oxigenio e Orleans Modificado com agitacao. Para a K. marxianus, a maior producao de etanol, 56,52 g.L 1, foi obtida para as seguintes condicoes de processo 29degC; pH (4,5) e 100 g.L 1 de permeado, com a S. boulardii alcancou se 69,43 g.L 1 de etanol, na fermentacao a 37degC; pH (6,0) e 300 g.L 1 de permeado. Na etapa acetica, obteve se 4,34g.100mL 1 de acido acetico para o ensaio oriundo da K. marxianus e fermentado aceticamente com a "mae do vinagre" e 4,23 g.100mL 1 para o ensaio da K. marxianus e A. aceti, todos fermentados pelo Metodo Orleans, os quais podem ser considerados vinagre, pois atingiram o previsto na legislacao brasileira (4% de acido acetico) Assim, com o presente estudo verificou se que e possivel produzir vinagre e fermentado acetico com o residuo lacteo permeado de soro de queijo. Com isso obter novos produtos e reduzir os danos ambientais causados por ele devido a reducao do seu potencial poluidor (DBO e DQO)
Maximizing Academic Library Collections: Measuring Changes in Use Patterns Owing to EBSCO Discovery Service
Venue: Coll. Res. Libr.
Year: 2015

Despite the prevalence of academic libraries adopting web scale discovery tools, few studies have quantified their effect on the use of library collections. This study measures the impact that EBSCO Discovery Service has had on use of library resources through circulation statistics, use of electronic resources, and interlibrary loan requests. Additionally, the data were compared against data from similar academic libraries without discovery systems. Findings include a strong growth in e journal use but a sharp decline in circulation statistics. Implications of discovery on use of the print collection are discussed along with suggestions for improving integration of book and article data. This article has been published in "College Research Libraries vol. 76 no. 1 81 99"
Drug associated hidradenitis suppurativa: A systematic review of case reports
Venue: Journal of the American Academy of Dermatology
Year: 2018

2. Gooderham M, Papp K. The psychosocial impact of hidradenitis suppurativa.  Patients' visual analog scale: a useful method of assessing psoriasis severity. Acta Derm Venereol. 2012;92:347 348. 5. Tavakol M, Dennick R. Making sense of Cronbach's alpha.  Educ. 2011;27:53 55.
Construction and application of a high content analysis for identifying human carboxylesterase 2 inhibitors in living cell system
Venue: Analytical and Bioanalytical Chemistry
Year: 2020

Human carboxylesterase 2 (hCE2) one of the most principal drug metabolizing enzymes, catalyzes the hydrolysis of a variety of endogenous esters, anticancer agents, and environmental toxicants. The significant roles of hCE2 in both endobiotic and xenobiotic metabolism sparked great interest in the discovery and development of efficacious and selective inhibitors. However, the safe and effective inhibitors of hCE2 are scarce, due to the lack of efficient screening and evaluation systems for complex biological systems. To offer a solution to this problem, a high content analysis (HCA) based cell imaging and multiparametric assay method was constructed for evaluating the inhibitory effect and safety of hCE2 inhibitors in living cell system. In this study, we first established a cell imaging based method for identifying hCE2 inhibitors at the living cell level with hCE2 fluorescent probe NCEN. Meanwhile, two nuclear probes, Hoechst 33342 and PI, were integrated to evaluate the potential cytotoxicity of compounds simultaneously. Then, the accuracy of the HCA based method was verified by the LC FD based method with a positive inhibitor BNPP, and the results showed that the HCA based method exhibited excellent precision, robustness, and reliability. Finally, the newly established HCA based multiparametric assay panel was successfully applied to re evaluate a series of reported hCE2 inhibitors in living cells. In summary, the HCA based multiparametric method could serve as an efficient tool for the accuracy measurement inhibitory effect and cytotoxicity of compounds against hCE2 in living cell system.
Bifunctional nitrogen doped hybrid catalyst based on onion like carbon and graphitic carbon encapsulated transition metal alloy nanostructure for rechargeable zinc air battery
Year: 2020

We demonstrate a facile approach for the synthesis of bifunctionally active nitrogen doped mesoporous hybrid material based on onion like carbon (OLC) and graphitic carbon encapsulated CoFe alloy for the fabrication of rechargeable zinc air battery (ZAB) The synthetic approach involves controlled temperature annealing of a homogenous mixture of cobalt and iron complexes of hydrolyzed collagen and the subsequent surface engineering by acid treatment. In situ generated CoFe alloy nanoparticle (12.5 nm) catalyzes the growth of OLC. CoFe nanoparticle is encapsulated with multi layer graphitic carbon shell. The surface engineered mesoporous catalyst has large surface area (659 m2 g 1) with interconnected mesopores. It is bifunctionally active towards oxygen reduction and oxygen evolution reactions with a potential gap of 0.8 V. It catalyzes oxygen reduction reaction in acidic and alkaline pHs and the kinetics of oxygen reduction in alkaline pH is highly facile with high electron transfer coefficient of 0.95. The Fe Nx sites of the catalyst actively participate in the oxygen reduction in acidic pH. Rechargeable ZAB is fabricated using the hybrid material based air cathode. It has high open circuit voltage (1.58 V) peak power density (102 mW/cm2) and remarkable charge discharge cycling stability. The overall performance is superior to that of the traditional catalyst based ZAB.