nils-herrmann/clean_scirepeval huggingface dataset:
An allopurinol controlled, multicenter, randomized, open label, parallel between group, comparative study of febuxostat (TMX 67) a non purine selective inhibitor of xanthine oxidase, in patients with hyperuricemia including those with gout in Japan: phase 2 exploratory clinical study.
Venue: Journal of clinical rheumatology practical reports on rheumatic musculoskeletal diseases
Year: 2011

Allopurinol has been widely used for the treatment of hyperuricemia, however, it may be associated with various adverse effects. Febuxostat has been identified as a potentially safe and efficacious alternative.  Febuxostat was administered to patients with hyperuricemia including gout in Japan to compare its efficacy and safety with those of allopurinol.  The starting dose of febuxostat and allopurinol was 10 and 100 mg/d, respectively, and was increased to the fixed maintenance dose of 40 or 60 mg/d for febuxostat and 300 mg/d for allopurinol for 16 weeks.  The percent change in the serum uric acid level at 16 weeks compared with the baseline serum uric acid level was 42.96% 13.33% and 52.47% 9.79% for the febuxostat 40 and 60 mg/d groups, respectively, and 36.55% 18.59% for the allopurinol group, indicating that the hypouricemic effects of febuxostat increased in a dose dependent manner and equaled to or surpassed those of allopurinol (P 0.0239, 2 sample t test) The percentage of patients with serum uric acid levels of 6.0 mg/dL or less at 16 weeks was 88.9% and 100% for the febuxostat 40 and 60 mg/d groups, respectively, and 68.8% for the allopurinol group, showing higher achievements for the febuxostat groups compared with the allopurinol group. All adverse drug reactions were mild to moderate in severity, and there were no severe symptoms or reactions leading to drug discontinuation.  These results suggest that febuxostat is safe at doses of 40 and 60 mg/d and has equal or greater efficacy than 300 mg/d allopurinol.
A Novel Two Level Nested STAP Strategy for Clutter Suppression in Airborne Radar
Venue: Mathematical Problems in Engineering
Year: 2019

Nested arrays have been studied recently in array signal processing field because of their closed form expressions for the sensor locations and achievable degrees of freedom (DOFs) In this paper, the concept of nesting is further extended to space time adaptive processing (STAP) Different from the traditional uniform STAP method that calculates the clutter plus noise covariance matrix (CNCM) and performs the STAP filter direct using the data snapshots collected from the uniform linear array (ULA) and the transmitting pulses with uniform pulse repetition interval (PRI) we present a new optimum two level nested STAP (O2LN STAP) strategy which employs an optimum two level nested array (O2LNA) and an optimum two level nested PRI (O2LN PRI) to exploit the enhanced DOFs embedded in the space time O2LN structure. Similar to the difference coarray perspective, we first construct a virtual space time snapshot from the direct covariance matrix of the received signals. Then, a new CNCM estimation corresponding to the virtual space time snapshot can be computed by the spatial temporal smoothing technique for STAP filter. Furthermore, the comparative simulations and analyses with the traditional uniform STAP and the recently reported coprime STAP are carried out to verify the effectiveness of the O2LN STAP approach.
The efficacy and use of finasteride in women: a systematic review
Venue: International journal of dermatology
Year: 2019

Physicians are beginning to use finasteride as treatment for hair loss, hirsutism, and various other dermatologic conditions in women. However, the reported efficacy and use of finasteride in the female population varies widely. The purpose of this study is therefore to better define the efficacy and use of finasteride in women and identify research gaps that require further investigation.
DIGESTION DE LOS LIPIDOS EN LOS RUMIANTES: UNA REVISION
Year: 2010

Las cualidades saludables de la carne y la leche de los rumiantes para el ser humano dependen, entre otros factores, del tipo y las proporciones de los acidos grasos que contienen, que a su vez estan estrechamente relacionadas con la digestion de los lipidos en dichas especies. Debido a las bacterias del rumen, los lipidos incluidos en la dieta que no estan protegidos en alguna forma sufren un proceso de lipolisis y biohidrogenacion que resulta en la saturacion de la mayoria de los acidos grasos insaturados consumidos. La extension del proceso depende de las caracteristicas de los lipidos (tipo y cantidad) y la dieta (efecto en el pH ruminal) Cuando se reduce la eficacia de la biohidrogenacion, se acumulan productos intermedios caracteristicos en el rumen, tales como el acido vaccenico e isomeros del acido linoleico conjugado, entre los que destaca el acido rumenico. A pesar de la ausencia de monogliceridos en la digesta duodenal, la digestibilidad intestinal de la grasa es elevada por la presencia de abundantes lisolecitinas biliares y microbianas. No obstante, distintos estudios sugieren que la digestibilidad intestinal disminuye, probablemente debido a la limitada produccion de bilis, al aumentar la cantidad de grasa consumida. Claramente, la digestion microbiana ruminal de los lipidos tiene la maxima influencia en la cantidad de los distintos tipos de acidos grasos que pasa al intestino delgado, en tanto que la digestion intestinal determina el valor energetico de la grasa extra incluida en la dieta
Anaerobic co digestion of organic fraction of municipal solid waste (OFMSW) Progress and challenges
Year: 2018

Anaerobic digestion (AD) of the organic fraction of municipal solid waste (OFMSW) offers the possibility of a clean and renewable energy source i.e. biogas. However, OFMSW lacks certain characteristics that may limit its efficacy as such a resource. Bio resources such as sewage sludge and animal wastes have these characteristics and so may be used to enhance OFMSW's digestion. Anaerobic co digestion (AcoD) of OFMSW with sewage sludge has been extensively studied and applied successfully at full scale. Pre treatments can increase substrate biodegradability and so biogas yield, but these may need further investigation to determine economic viability. Mathematical modeling has been shown useful in aiding selection of appropriate combinations of substrates and pretreatment for co digestion (e.g. substrate type and mix ratio) This review also considers the fate of the digestate following such anaerobic co digestion. The difficulties in implementation of the co digestion approach need not necessarily be technical in nature but can be due to management issues.
Analyzing Sentence Fusion in Abstractive Summarization
Venue: EMNLP
Year: 2019

While recent work in abstractive summarization has resulted in higher scores in automatic metrics, there is little understanding on how these systems combine information taken from multiple document sentences. In this paper, we analyze the outputs of five state of the art abstractive summarizers, focusing on summary sentences that are formed by sentence fusion. We ask assessors to judge the grammaticality, faithfulness, and method of fusion for summary sentences. Our analysis reveals that system sentences are mostly grammatical, but often fail to remain faithful to the original article.
Overall survival and response pattern of castration resistant metastatic prostate cancer to multiple cycles of radioligand therapy using [177Lu]Lu PSMA 617
Venue: European Journal of Nuclear Medicine and Molecular Imaging
Year: 2017

PurposeUp to 30% of patients with castration resistant prostate cancer (CRPC) do not show any response to the first cycle of radioligand therapy (RLT) with [177Lu]Lu PSMA 617 (Lu PSMA) We evaluated patient response to the second and third cycles of RLT in patients that underwent at least three cycles. The second aim of this study was to calculate the median overall survival (OS) of responders and non responders after the first cycle and after all three cycles of RLT.MethodsCRPC patients were treated with Lu PSMA, with a median interval of 8 weeks between each cycle. The tumour marker prostate specific antigen (PSA) was used as the marker for response evaluation.ResultsFifty two patients underwent a total of 190 cycles of RLT (3 6 cycles per patient) Of these, 80.8% showed a decline in PSA 2 months after the first cycle, with 44.2% showing a PSA decline of =50% When compared to baseline PSA, 73.1% showed a PSA decline after the third cycle. 50% of patients that did not show any response to the first cycle also did not respond to the second and third cycles. The median OS was 60 weeks in all patients. The median OS was significantly longer for patients that showed any PSA decline after the first cycle compared to patients without PSA decline (68 vs. 33 weeks) There was a significant difference in median OS between responders and non responders for a change in PSA after the third cycle compared to baseline PSA.ConclusionPatients with a positive response to RLT, regardless of the rate of decline, had a significantly longer median OS. Of the patients that did not show any response to the first cycle, 50% responded to the second or third cycles.
Hit Detector: Hierarchical Trinity Architecture Search for Object Detection
Venue: 2020 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
Year: 2020

Neural Architecture Search (NAS) has achieved great success in image classification task. Some recent works have managed to explore the automatic design of efficient backbone or feature fusion layer for object detection. However, these methods focus on searching only one certain component of object detector while leaving others manually designed. We identify the inconsistency between searched component and manually designed ones would withhold the detector of stronger performance. To this end, we propose a hierarchical trinity search framework to simultaneously discover efficient architectures for all components \ie backbone, neck, and head) of object detector in an end to end manner. In addition, we empirically reveal that different parts of the detector prefer different operators. Motivated by this, we employ a novel scheme to automatically screen different sub search spaces for different components so as to perform the end to end search for each component on the corresponding sub search space efficiently. Without bells and whistles, our searched architecture, namely Hit Detector, achieves 41.4\ mAP on COCO minival set with 27M parameters. Our implementation is available at \href{https:/github.com/ggjy/HitDet.pytorch}{https:/github.com/ggjy/HitDet.pytorch}
Investigasi Geologi dan Geolistrik Untuk Menafsirkan Keberadaan Air Tanah Dangkal Di Ambarawa, Lampung
Year: 2018

East Ambarawa has a large agricultural land prosfek for rice cultivation. Limitations of irrigation facilities, caused land fields are only productive in the rainy season. Utilization of ground water to be an alternative to supporting water supply. For this purpose, a geoelectric survey has been conducted to map the presence of shallow groundwater in three lines with random positions using Pole pole configurations. Through the use of 40 electrodes with a total length of 200 m, geoelectric image is obtained to a depth of 70 m. The presence of ground water is interpreted to be in sedimentary layers, at depths of 12 50. Underlying sediment layers are composed of igneous rocks that correlate with the formed Kerawang hill.
Chronotype mediates gender differences in risk propensity and risk taking
Venue: PloS one
Year: 2019

Risk taking is a complex form of decision making that involves calculated assessments of potential costs and rewards that may be immediate or delayed. Thus, making predictions about inter individual variation in risk taking due to personality traits, decision styles or other attributes can be difficult. The association of risk taking with gender is well supported; males report higher propensity for risk taking and show higher risk taking on tasks measuring actual risk taking behavior. Risk taking also appears to be associated with circadian phenotypes (chronotypes) with evening types reporting higher levels of risk taking but this association may be confounded by the fact that, in certain age groups, males are more likely to be evening types. Here, we test for gender by chronotype effects on risk taking in young adults (n 610) using a self reported risk propensity questionnaire, the health domain of the DOSPERT, and a behavioral task measuring risk taking, the Balloon Analog Risk Task (BART) Our results show that males report and take significantly more risks than females in this population. In addition, evening type individuals have significantly higher self reported risk propensity and tend to take more risks on the BART. Interestingly, there is no significant difference in risk propensity or risk taking behavior across male circadian phenotypes, but evening type females significantly report and take more risk than female intermediate and morning types. In regression analyses, we found both gender and chronotype predict risk propensity and risk taking. Path analysis confirms that chronotype has an indirect effect on gender differences in both risk propensity and risk taking. Furthermore, we found that trait anxiety (STAI) and sleep disturbance (PROMIS) significantly correlate with chronotype and gender in the complete dataset, but do not independently predict differences in female risk taking. These results suggest that chronotype mediates gender effects on risk taking and that these effects are driven primarily by morning type females, but are not related to gender specific differences in trait anxiety or sleep quality.
Looking for digital in public relations
Year: 2015

The purpose of this study was to review the growth of the body of knowledge on the nexus between public relations and ICTs, and digital, social and mobile (DSM) media. We also sought to assess whether these "new" media had induced the body of knowledge to redefine the term public and whether these media had induced us to think differently with regard to the rules of engagement with these publics. Our review of over 35 years of articles in the Public Relations Review that discussed ICTs and DSM media revealed a lop sided growth of the field. But the focus has almost exclusively been on using these media as "tools" for purposes of media relations with negligent study of DSM media stakeholders and publics. Issues of the Digital Divide and Privacy are absent, while amalgamation of public relations, advertising and journalism in DSM media is overlooked.
Modern nutrigenomics and nutrigenetics and some metabolic aspects of pathogenesis in inflammatory bowel diseases: a look into the future
Year: 2020

The implementation of the target setting for the treatment of inflammatory bowel diseases the achievement of clinical and endoscopic remission in each case, even taking into account biological therapy drugs, is not always achievable. It is obvious that patients with ulcerative colitis and Crohn's disease are genetically heterogeneous in nature, which is manifested by the formation of various clinical and genetic phenotypes and various profiles of altered intestinal microbiota. Modern dietetics and nutritionology can be the most important fine tuning tool in this chain of events and significantly increase the effectiveness of the therapy, equally contributing to both normalization of the intestinal microbial community and providing mechanisms for regulating gene expression (epigenetic effect)
Celonis Process Repository: A Bridge between Business Process Management and Process Mining
Venue: BPM
Year: 2020

Process Mining disrupted Business Process Management (BPM) in various ways from process modeling to analysis, redesigning, implementing, and monitoring of processes. One of the big challenges of traditional ways to identify and discover process models are the very time consuming and costly procedures due to lengthy interviews and workshops that result in a conceptual model and not representing the real executed process (As Is process) Process Repository is a recently developed toolset by Celonis that brings BPM and Process Mining closer together by providing process documentation capabilities and fully integrating them with Process Mining applications.
TLC analysis and antioxidant activity of garden egg leaves
Year: 2020

1 Umar, U. A. Department of Chemistry, Sokoto State University, Sokoto Department of Pure and Applied Chemistry, Usmanu Danfodiyo University, Sokoto * The Solanum melongena is used traditionally to treat different diseases such as cancer, atherosclerosis, and inflammation. This study is aimed at investigating the thin chromatography analysis and antiox leaves extract of Solanum melongena. Sequential extraction with solvents of increasing polarity was carried out using the n chromatography of the extracts c activity was evaluated quantitatively using DPPH (2, 2 free radical scavenging ability. The results of thin spots with Rf values in the respective extracts, n 0.85, 0.92) acetone (0.97, 0.92, 0.88 and 0.59) and 0.96) The extracts exhibit strong antioxidant activities as radical scavengers, indicatin that they have strong proton donating abilities. credence to the traditional application of the plant. Further research is recommended on the isolation and characterization of the antioxidant compounds from the plant.
Pursuing the Increase of Factory Automation in 200mm Frontend Manufacturing to Manage the Changes Imposed by the Transitionfrom High Volume Low Mix to High Mix Low Volume Production
Venue: 2008 IEEE/SEMI Advanced Semiconductor Manufacturing Conference
Year: 2008

We regard the stringent adoption of factory automation as the right strategy to efficiently leverage a 200 mm fab's competitiveness. In this article we exemplarily show how the Dresden fab cut its own path in the face of the transition challenge from a high volume low mix fab to a high mix low volume fab. We discuss the advantages of our conveyor type transport system with respect to our automation strategy and its extendibility to direct tool loading. A comparison of our transport system with typical 300 mm performance data and current ITRS requirements  is presented. We describe the positive influence of the taken factory automation measures on typical key manufacturing indicators like cycle time, tool utilization, head count efficiency, variability improvement, cost efficiency and quality.
Pinning Adaptive Synchronization of Delayed Coupled Dynamical Networks via Periodically Intermittent Control
Year: 2017

This paper investigates the exponential synchronization problem of delayed coupled dynamical networks by using adaptive pinning periodically intermittent control. Based on the Lyapunov method, by designing adaptive feedback controller, some sufficient conditions are presented to ensure the exponential synchronization of coupled dynamical networks with delayed coupling. Furthermore, a numerical example is given to demonstrate the validity of the theoretical results.
Aprendizaje Servicio e inclusion en educacion primaria. Una vision desde la Educacion Fisica. Revision sistematica (Service Learning and inclusion in primary education. A vision from Physical Education. Systematic review)
Venue: Retos
Year: 2019

El Aprendizaje Servicio, como metodologia educativa que auna aprendizaje y servicio comunitario en un unico proyecto con base civica y academica, es una opcion realmente interesante para aplicar en la etapa de educacion primaria y, concretamente, en Educacion Fisica, por su caracter eminentemente practico, su estrecha relacion con el sistema de valores personales, sociales y civicos, y porque puede vincularse con el afrontamiento de las necesidades educativas especiales. El objetivo de este trabajo fue conocer y analizar los estudios relativos a Aprendizaje Servicio, Educacion Fisica e inclusion en la etapa de educacion primaria en Espana, a partir de una revision sistematica de documentos publicados en tres grandes bases de datos: ERIC, Dialnet y Google Scholar. Los resultados nos muestran un escaso bagaje publicado en torno a esta tematica, destacando el tratamiento que se hace de esta metodologia en el ambito universitario y, en menor medida, proyectos vinculados a centros escolares de educacion primaria y la Educacion Fisica, que hacen referencia a la forma en que esta metodologia contribuye a la mejora de procesos de integracion, inclusion y atencion a la diversidad del alumnado de educacion primaria.The Service Learning, as educational methodology that combines learning and community service in a single project with a civic and academic base, is a really interesting option to apply in primary education and, especifically, in Physical Education, because it has an eminently practical nature, the close relationship with the system of personal, social and civic values, and because it can be linked with the especial educational needs. The aim of this work was to know and analyze the studies related to Service Learning, Physical Education and inclusion in the primary education stage in Spain, from a systematic review of documents published in three big databases: ERIC, Dialnet and Google Scholar. The results show us a scarce baggage published around this topic, highlighting the treatment that is made of this methodology in the university environment and, to a lesser extent, projects linked to primary and Physical Education schools, which make reference to the way in which this methodology contributes to the improvement of integration processes, inclusion and attention to the diversity of the students of primary education.
Fundamentos del diseno de un modelo de atencion de Enfermeria para la gestion del cuidado
Year: 2018

Los modelos representan un sistema auxiliar y un sustento filosofico en el proceso de gestion del cuidado para la ciencia enfermera, enmarcan lo esencial de la profesion y proveen los servicios asistenciales.  Identificar las bases filosoficas y metodologicas en el diseno de un modelo de atencion de Enfermeria para la gestion del cuidado en la especialidad de Oftalmologia.  Revision sistematica con analisis critico reflexivo de documentos y articulos originales publicados en espanol e ingles entre 1999 y 2015 con las palabras clave: "modelos" "modelos teoricos" y "modelos de atencion de Enfermeria" en las bases de datos Scielo, Ebsco, Lilacs y Medline/Pubmed, que facilitaron realizar triangulacion de la informacion para sustentar teorica y metodologicamente un modelo de atencion de Enfermeria.  Se identifican como referente filosofico a la teoria de los sistemas de Enfermeria propuesto por Dorothea Orem, el Holismo y la simultaneidad de Martha Elizabeth Rogers, asi como las competencias y los siete dominios de Patricia Benner. Se adopta como metodologia al Proceso de atencion de Enfermeria.
Cracking the nut of agribusiness and global food insecurity: In search of a critical agenda of research
Year: 2015

The article examines some of the main trends of the modernisation of agribusiness and raises some questions about geographical transformations taking place in the centre and north of Brazil. The country represents an emblematic case of neo liberalised agriculture in need of further investigation. It is discussed in the text how corporate, industrial scale agribusiness practices in Brazil bring back some spectral elements of capitalism, which never disappeared and in which the invisible becomes visible again. It is a phenomenon of multiple dialectics that needs further theoretical, methodological and investigative elaboration. The most dramatic circumstances, and most interesting for academics to study, are at the frontier of the expansion of agribusiness, where spatially and temporally patterns are heterogeneous and largely unpredictable. Agribusiness is especially promoted at the agriculture frontier in Brazil because it is in itself an economic, ecological and ethical frontier. Therefore, critical research into the complexity of contemporary agribusiness should really be about the political economy of alternatives to the highly vulnerable and unsatisfactory approaches to food and agriculture that prevail today and continue to expand unabated.