nils-herrmann/clean_scirepeval huggingface dataset:
kNN Classification with an Outlier Informative Distance Measure
Venue: PReMI
Year: 2017

Classification accuracy of the kNN algorithm is found to be adversely affected by the presence of outliers in the experimental datasets. An outlier score based on rank difference can be assigned to the points in these datasets by taking into consideration the distance and density of their local neighborhood points. In the present work, we introduce a generalized outlier informative distance measure where a factor based on the above score is used to modulate any potential distance function. Properties of the new outlier informative distance measure are presented. Experiments on several numeric datasets in the UCI machine learning repository clearly reveal the effectiveness of the proposed formulation.
Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia
Venue: Pediatric blood cancer
Year: 2019

Acute myeloid leukemia (AML) is a heterogeneous disease regarding morphology, immunophenotyping, genetic abnormalities, and clinical behavior. The overall survival rate of pediatric AML is 60% to 70% and has not significantly improved over the past two decades. Children with Down syndrome (DS) are at risk of developing acute megakaryoblastic leukemia (AMKL) which can be preceded by a transient myeloproliferative disorder during the neonatal period. Intensification of current treatment protocols is not feasible due to already high treatment related morbidity and mortality. Instead, more targeted therapies with less severe side effects are highly needed.
Hollaback! the role of storytelling online in a social movement organization
Venue: CSCW
Year: 2013

CSCW systems are playing an increasing role in activism. How can new communications technologies support social movements? The possibilities are intriguing, but as yet not fully understood. One key technique traditionally leveraged by social movements is storytelling. In this paper, we examine the use of collective storytelling online in the context of a social movement organization called Hollaback, an organization working to stop street harassment. Can sharing a story of experienced harassment really make a difference to an individual or a community? Using Emancipatory Action Research and qualitative methods, we interviewed people who contributed stories of harassment online. We found that sharing stories shifted participants' cognitive and emotional orientation towards their experience. The theory of "framing" from social movement research explains the surprising power of this experience for Hollaback participants. We contribute a way of looking at activism online using social movement theory. Our work illustrates that technology can help crowd sourced framing processes that have traditionally been done by social movement organizations.
A descriptive survey of the information needs of parents of children admitted for same day surgery.
Venue: Journal of pediatric nursing
Year: 2013

Going to the hospital for surgery is an event that most people may find daunting. Anticipation of the unknown, lack of control over events and unfamiliarity with the environment may result in feelings of anxiety and stress. This research paper used a quantitative descriptive survey to establish the information needs of parents of children admitted for same day surgery. The main aims of this study were to establish what information parents had received prior to their child's admission for same day surgery, and how they perceived this information. It also determined what other information they required. The findings demonstrated that the majority of parents in this study were satisfied with the information they had received. However they wanted further advice on the waiting times involved, the equipment used in the operating room department, pain relief and the procedures in the recovery room.
Approximate dynamic programming for missile defense interceptor fire control
Venue: Eur. J. Oper. Res.
Year: 2017

Given the ubiquitous nature of both offensive and defensive missile systems, the catastrophe causing potential they represent, and the limited resources available to countries for missile defense, optimizing the defensive response to a missile attack is a necessary national security endeavor. For a single salvo of offensive missiles launched at a set of targets, a missile defense system protecting those targets must determine how many interceptors to fire at each incoming missile. Since such missile engagements often involve the firing of more than one attack salvo, we develop a Markov decision process (MDP) model to examine the optimal fire control policy for the defender. Due to the computational intractability of using exact methods for all but the smallest problem instances, we utilize an approximate dynamic programming (ADP) approach to explore the efficacy of applying approximate methods to the problem. We obtain policy insights by analyzing subsets of the state space that reflect a range of possible defender interceptor inventories. Testing of four instances derived from a representative planning scenario demonstrates that the ADP policy provides high quality decisions for a majority of the state space, achieving a 7.74% mean optimality gap over all states for the most realistic instance, modeling a longer term engagement by an attacker who assesses the success of each salvo before launching a subsequent one. Moreover, the ADP algorithm requires only a few minutes of computational effort versus hours for the exact dynamic programming algorithm, providing a method to address more complex and realistically sized instances.
El control interno y las pymes
Year: 2019

En Latinoamerica, tambien en Ecuador, las Pymes han alcanzado un peso significativo; no obstante, en promedio, ellas fracasan en el corto plazo. En gran medida las causas de ello tienen un origen interno. Atendiendo a esto, el objetivo de este trabajo es examinar los beneficios que puede aportar a las Pymes utilizar un enfoque integrado del "Control Interno" Para la investigacion se utilizo un metodo cualitativo, con fundamento analitico y de interpretacion documental. Se concluye que el enfoque integrado debe incluir en su concepcion la coexistencia equilibrada entre el beneficio individual y social, construir relaciones de produccion, de intercambio y de cooperacion que propicien la eficiencia y calidad, sustentadas en la solidaridad; asimismo, la medicion de la productividad y competitividad tendran como base los avances de la colectividad. A su vez, debe ser apoyado y monitoreado por el Estado, quien tiene que concebirlo como parte de su estrategia de desarrollo.
The complexity of medicinal plants: the traditional Artemisia annua formulation, current status and future perspectives.
Venue: Journal of ethnopharmacology
Year: 2013

ETHNOPHARMACOLOGICAL RELEVANCE Artemisia annua has a long tradition of use for the treatment of intermittent fevers which we now relate to malarial infections. The active principle artemisinin has been isolated from Artemisia annua and today forms the backbone of the global fight against malaria. The traditionally prepared Artemisia annua formulation is however still being used on a global scale for the treatment of malaria, and it is claimed that its action is superior to the single purified drug. Artemisia annua is therefore on the forefront of the heated debate between the single drug single target approach of western based medicine and the holistic approach of traditional medicinal systems. This review aims to highlight the complexities we face in the general study of medicinal plants at the hand of three levels of complexity. These levels consist of (a) the chemistry of the medicinal plant, (b) the influence of the preparation method on the chemistry of the final formulation and (c) the influence of metabolism on the chemistry of the formulation. We also aim to provide an up to date report on all scientific work that has been conducted and published in English on the traditional formulation of Artemisia annua.  English scientific literatures published until the first quarter of 2013 were retrieved from well known scientific databases (Scifinder scholar, Web of Science, PubMed, Google scholar) and Non governmental organisations active in this field were consulted. A draft version of this manuscript was sent to the African office of the World Health Organisation (WHO) and to the Non governmental organisations "Action Medicine Naturelle" (ANAMED) and "Iwerliewen fir bedreete Volleker Reseau belgo luxembourgeois pour la valorisation des herbes medicinales" (IFBV BELHERB) for comments.  Very little scientific work has been conducted on the Artemisia annua formulation. The available literature contains many discrepancies which are unfortunately selectively being used by the two different sides in this debate to further their arguments. On one side of the argument we have the low content of artemisinin in Artemisia annua, the low bioavailability of artemisinin when the traditional formulation is administered and the high levels of recrudescence, which are being emphasised, while on the other side the possible role of synergism and prodrugs are being highlighted. This review reports that there are still too many gaps in our existing knowledge to provide conclusive evidence for either of the two sides of the argument.  Much more research is needed into Artemisia annua formulations. We stand to gain invaluable knowledge into how traditional medicinal plant works, discover the identities of new active compounds (which can be used against other diseases such as HIV, diarrhoea, and cancer) and possibly bring both sides of this debate closer together.
OPTIMASI FORMULA SPRAY GEL EKSTRAK KOLAGEN KULIT IKAN GABUS (Channa striata) VARIASI KONSENTRASI HPMC 60SH CARBOPOL(r)940 MENGGUNAKAN DESAIN FAKTORIAL
Year: 2020

Kulit ikan gabus mengandung senyawa kolagen yang berperan dalam fase proliferasi dan maturasi dalam penyembuhan luka bakar. Kolagen kulit ikan gabus diekstraksi dengan metode Acid Soluble Collagen (ASC) menggunakan asam asetat 0,5 M dan memiliki rendemen sebesar 2,321% Ekstrak kolagen kulit ikan gabus diformulasikan menjadi bentuk sediaan spray gel untuk mengurangi kontaminasi atau infeksi serta rasa sakit ketika diaplikasikan pada bagian luka. Spray gel diformulasikan menggunakan HPMC 60SH dan Carbopol(r)940 sebagai gelling agent. Kedua gelling agent dioptimasi menggunakkan program Design Expert(r)10 dengan metode desain faktorial 22. Konsentrasi gelling agent yang dioptimasi sebesar 0,5% sebagai low level dan 2% sebagai high level. Sediaan dievaluasi sifat fisik yang meliputi organoleptis, homogenitas, viskositas, pH, daya lekat, daya tercuci, pola penyemprotan, dan pump delivery. Hasil pengujian dianalisis dengan DX(r)10 untuk mendapatkan formula optimum. Didapatkan konsentrasi optimum HPMC 60SH 1,733% dan Carbopol(r)940 1,807% memiliki diameter pola penyemprotan 1,013 0,033 cm, pH 7,067 0,0603, daya lekat pada kulit 24,107 0,067 detik, daya lekat pada kertas saring 24,273 0.103 detik, daya tercuci 6,333 0,289 mL, dan pump delivery 6,447%
Estimation of PM2.5 mortality burden in China with new exposure estimation and local concentration response function.
Venue: Environmental pollution
Year: 2018

The estimation of PM2.5 related mortality is becoming increasingly important. The accuracy of results is largely dependent on the selection of methods for PM2.5 exposure assessment and Concentration Response (C R) function. In this study, PM2.5 observed data from the China National Environmental Monitoring Center, satellite derived estimation, widely collected geographic and socioeconomic information variables were applied to develop a national satellite based Land Use Regression model and evaluate PM2.5 exposure concentrations within 2013 2015 with the resolution of 1 km x 1 km. Population weighted concentration declined from 72.52 mg/m3 in 2013 to 57.18 mg/m3 in 2015. C R function is another important section of health effect assessment, but most previous studies used the Integrated Exposure Regression (IER) function which may currently underestimate the excess relative risk of exceeding the exposure range in China. A new Shape Constrained Health Impact Function (SCHIF) method, which was developed from a national cohort of 189,793 Chinese men, was adopted to estimate the PM2.5 related premature deaths in China. Results showed that 2.19 million (2013) 1.94 million (2014) 1.65 million (2015) premature deaths were attributed to PM2.5 long term exposure, different from previous understanding around 1.1 1.7 million. The top three provinces of the highest premature deaths were Henan, Shandong, Sichuan, while the least ones were Tibet, Hainan, Qinghai. The proportions of premature deaths caused by specific diseases were 53.2% for stroke, 20.5% for ischemic heart disease, 16.8% for chronic obstructive pulmonary disease and 9.5% for lung cancer. IER function was also used to calculate PM2.5 related premature deaths with the same exposed level used in SCHIF method, and the comparison of results indicated that IER had made a much lower estimation with less annual amounts around 0.15 0.5 million premature deaths within 2013 2015.
[Clinical effects of Kirschner wire with hole transverse fixation combined with titanium cable purse string suture for the treatment of refractory fracture of patellar comminuted fracture]
Venue: Zhongguo gu shang China journal of orthopaedics and traumatology
Year: 2018

To explore clinical effects of Kirschner wire with hole transverse fixation combined with titanium cable purse string suture in treating refractory fracture of patellar comminuted fracture.  From January 2014 to January 2016, 17 comminuted fracture treated by Kirschner wire with hole transverse fixation combined with titanium cable purse string suture were retrospectively analyzed, including 10 males and 7 females aged from 28 to 67 years old with an average of (48.7+ 3.2) years old. According to AO/OTA fracture classification, all fractures were type 34 C3.2. Operative time, blood loss, intervals of the first functional exercise postoperatively and complications were observed. Meanwhile, function recovery was evaluated by Bostman scoring at 10 months after operation.  All patients were followed up with an average of(14.6+ 2.1) months ranged from 10 to 24 months. All incisions healed at stage I. Clinical fracture healing time ranged from 11.7 to 16.5 weeks with an average of (12.7+ 1.7) weeks; operative time ranged from 67 to 95 min with an average of (71.4+ 11.5) min; blood loss ranged from 41 to 72 ml with an average of (57.0+ 7.5) ml; the first time of functional exercise ranged from 2 to 5 d with an average of (2.2+ 1.7) d. No complications including Kirschner pin stabbing the skin, loose or slippery of Kirschner pin, bursitis with pain brought by tip of Kirschner pin, wire escaped and broken occurred. Postoperative Bostman score at 10 months were 28.15+ 1.74, 12 patients got excellent results, 4 well and 1 lose.  Kirschner wire with hole transverse fixation combined with titanium cable purse string suture in treating refractory fracture of patellar comminuted fracture has advantages of simple operation, good anatomical reduction, stable fixation and less complications, which is worth popularizing.
GREEN TRIBOLOGY AND QUALITY OF LIFE UDC
Year: 2012

Every system is immersed in its surrounding. The changes in this interaction (contact) leading to degradation processes will affect the safety of the system. If the processes of changes are in a steady state, it can be considered that the system is safe. Sustainability includes the quality merits. Being the science and technology of the tribological aspects in the ecological balance and environmental impacts, Green tribology can be used with the purpose of saving of energy and materials, as well as of enhancement of the environment and the quality of life. Following the principles of green tribology, by identifying safety related requirements early in the development of the system, special design and technologies can be used throughout the system life to conduct its safe development and evolution.
Topological interface states mediated by spontaneous symmetry breaking
Year: 2018

We propose a one dimensional nonlinear system of coupled anharmonic oscillators that dynamically undergoes a topological transition switching from the {disordered} and topologically trivial phase into the nontrivial one due to the spontaneous symmetry breaking. The topological transition is accompanied by the formation of the topological interface state in the spectrum of linearized excitations of the stationary phase. Our findings thus highlight the potential of the nonlinear systems for hosting the topological phases and uncover a fundamental link between the spontaneous symmetry breaking mechanism and topological edge states.
Graph based Topic Extraction from Vector Embeddings of Text Documents: Application to a Corpus of News Articles
Venue: COMPLEX NETWORKS
Year: 2020

Production of news content is growing at an astonishing rate. To help manage and monitor the sheer amount of text, there is an increasing need to develop efficient methods that can provide insights into emerging content areas, and stratify unstructured corpora of text into `topics' that stem intrinsically from content similarity. Here we present an unsupervised framework that brings together powerful vector embeddings from natural language processing with tools from multiscale graph partitioning that can reveal natural partitions at different resolutions without making a priori assumptions about the number of clusters in the corpus. We show the advantages of graph based clustering through end to end comparisons with other popular clustering and topic modelling methods, and also evaluate different text vector embeddings, from classic Bag of Words to Doc2Vec to the recent transformers based model Bert. This comparative work is showcased through an analysis of a corpus of US news coverage during the presidential election year of 2016.
Estimation in a semiparametric partially linear errors in variables model with inverse Gaussian kernel
Venue: Communications in Statistics Theory and Methods
Year: 2019

This paper proposes an estimation procedure for the partial linear regression models, when the explanatory variable of the non parametric component is supported on and the covariates in the parametric part are contaminated by the measurement errors. Bias corrected estimators for the regression parameters and the non parametric components are constructed when the model errors are homoscedastic and heteroscedastic. Under some regularity conditions, large sample properties, including the consistency and asymptotic normality of the proposed estimators, are discussed. Simulation studies and real data analysis are conducted to evaluate the finite sample performance of the proposed estimation procedure.
Aortic valve sparing and hybrid arch frozen elephant trunk repair for mega aortic syndrome.
Venue: Annals of cardiothoracic surgery
Year: 2020

A 69 year old female presented with increasing shortness of breath (NYHA class II) and was previously followed for aneurysmal dilatation of her thoraco abdominal aorta with a chronic type B aortic dissection. Repeat computed tomography (CT) demonstrated severe dilatation of her ascending aorta, aortic arch, descending aorta, and thoraco abdominal aorta with the chronic type B aortic dissection extending from the proximal descending thoracic aorta to the renal arteries. Pre operative transthoracic echocardiography revealed moderate central aortic insufficiency with a dilated aortic root and ascending aorta. Other past medical history included an ongoing 50 packyear smoking history, chronic obstructive pulmonary disease, and remote cholecystectomy. We performed a pre operative left carotid subclavian bypass before aortic arch reconstruction, in order to facilitate more proximal arch anastomosis and shorten circulatory arrest times (1) The patient was subsequently brought to the hybrid operating room, where we describe the hybrid arch frozen elephant trunk reconstruction performed with aortic valve sparing operation using the reimplantation technique.
The integrating of architecture and nature into environmental objects in mountainous terrain
Year: 2018

The article examines the topical issue of interaction between architecture and nature. This paper considers the basic principles and techniques of nature integrated design that allow reducing the contradictions between the artificially created architectural and the natural environment, which is a fundamentally important condition for sustainable development. Based on global experience, principal means of harmonization are indicated, such as architectural and landscape composition, visual perception, defining the aesthetics. Special attention is paid to the goals and tasks of creating not only multi comfortable, functionally expedient and viable buildings, but also the optimal preservation and harmonious inclusion of environment elements in a common architectural ensemble. The implementation of the basic principles is shownby the example of the author's project "The Ezhovaya Mountain Recreation Center" in Kirovgrad, Sverdlovsk region, such as the preservation of a unique natural site, the regeneration and interaction of spaces. Detailed consideration is given to the construction of a building complex in highlands, where specific factors and their influence on the processes of construction and operation were taken into account.
Simulation and implementation of Variable Duty Cycle Control to Achieve High Input Power Factor for DCM Boost PFC Converters
Year: 2012

A discontinuous conduction mode (DCM) boost power factor correction (PFC) converter features zero current turn on for the switch, no reverse recovery in diode, and constant frequency operation. But the input power factor (PF) is relatively low when the duty cycle is constant. This paper describes variable duty cycle control to achieve high input power factor for DCM boost power factor correction converters.
Could long term follow up modify the outcomes after laparoscopic TAPP? A 5 year retrospective cohort study
Venue: Hernia
Year: 2019

PurposeLaparoscopic inguinal hernia repair (LIHR) has demonstrated multiple benefits. However, long term results regarding recurrence and quality of life (QoL) are still on debate. We aimed to analyze postoperative outcomes with long term follow up after LIHR.MethodsA consecutive series from December 2012 to May 2017 of laparoscopic TAPP was included. A minimum of 6 months of follow up was required for inclusion. The sample was divided into two groups, G1: patients with recurrence and G2: patients without recurrence. Patient's characteristics, operative variables and postoperative outcomes were analyzed. A QoL survey (Eura HS QoL) was performed in the pre and postoperative period. total of 717 laparoscopic TAPP were performed in 443 patients. On univariate analysis, smoking, previous recurrence, mesh size smaller than 12 x 15 cm and surgical teams with less than 30 cases/year showed an increased recurrence rate (p 0.05) But only smoking and less experienced teams were statistically significant on multivariate analysis (p 0.01) After a 2 year follow up, recurrence rate was 1.5% while it increased to 2.6% (n 19) at 5 year follow up. Sixty percent of patients answered QoL survey. Average preoperative scores of pain, activities restriction and aesthetic dissatisfaction improved significantly after 6 months of follow up in patients without recurrence.ConclusionsAfter LIHR, quality of life shows a significant improvement in all parameters. Extending follow up beyond 2 years after laparoscopic TAPP allows a more accurate assessment of recurrence rate. Smoking and inexperienced teams were significant risk factors for its development.