nils-herrmann/clean_scirepeval huggingface dataset:
Clinical Study and Rapid Detection of Feline Parvovirus in Suspected Cats by Polymerase Chain Reaction Method
Year: 2020

The aim of this research was to detect the presence of Feline Parvovirus (FPV) in blood samples of FPV suspected cats by Polymerase Chain Reaction (PCR) method. This research used eleven fresh blood samples of FPV suspected cats which were obtained from the Internal Medicine Laboratory of Faculty of Veterinary Medicine at UGM, Yogyakarta, Clinic Pet Care in Semarang and Medania Private Clinic in Yogyakarta. The DNA was first extracted from the blood using DNA isolation kit. Then the template of DNA was used for amplification by PCR method using CPV primers to target the Viral Protein 2 (VP 2) encoding gene. The PCR products were then visualized using 1% Agarose Gel electrophoresis and UV Transilluminator. A positive result was indicated by the appearance of a DNA fragment in size of 518 bp which can be interpreted as the presence of FPV in the obtained blood samples. PCR products were then sent for sequencing to determine the nucleotide sequence of the VP 2 gene. The sequences obtained were aligned using multiple alignment method with three FPV isolates obtained from the database of Genebank using the MEGA6.06 software program. From the eleven cat blood samples obtained, 8 samples indicated positive with FPV infection. This results showed that PCR method can be used to detect FPV in samples derived from blood specimens from FPV suspected cats. Conventional PCR method was also used to confirm the cause of the symptoms shown by the infected cats as some of the symptoms such as gastroenteritis is quite common among many other viral infection.
Sindrome de Cushing
Year: 2020

Resumen La exposicion cronica a un exceso de glucocorticoides es responsable de las diversas manifestaciones del sindrome de Cushing, de un deterioro de la calidad de vida y de un aumento de la morbimortalidad, en particular cardiovascular. Es necesario establecer un diagnostico precoz para limitar los efectos deletereos del hipercortisolismo cronico, pero el diagnostico de sindrome de Cushing, la identificacion de su etiologia asi como las opciones terapeuticas pueden resultar dificiles. La primera etapa consiste en confirmar el diagnostico de hipercortisolismo y descartar los diagnosticos diferenciales. La segunda etapa es etiologica: su objetivo es ante todo estudiar el caracter dependiente o independiente con respecto a la secrecion de ACTH (hormona adrenocorticotropa) e identificar a continuacion la lesion causante del sindrome de Cushing. La tercera etapa es terapeutica, donde el tratamiento optimo consiste en una reseccion completa del tumor causal, independientemente de la etiologia del sindrome de Cushing. Cuando dicha reseccion no es posible o en caso de contraindicacion o fracaso quirurgico, el tratamiento se basa en farmacos inhibidores de la sintesis de cortisol o de la secrecion de ACTH, o en la adrenalectomia. El riesgo de recidiva en algunas etiologias, los efectos a largo plazo del exceso de cortisol y las comorbilidades asociadas al hipercortisolismo requieren un seguimiento prolongado de estos pacientes.
Association between Perceived Neighborhood Built Environment and Walking and Cycling for Transport among Inhabitants from Latin America: The ELANS Study
Venue: International journal of environmental research and public health
Year: 2020

This study aimed to examine the associations of the perceived neighborhood built environment with walking and cycling for transport in inhabitants from Latin American countries.  This cross sectional study involved 9218 participants (15 65 years) from the Latin American Study of Nutrition and Health, which included a nationally representative sample of eight countries. All participants completed the International Physical Activity Questionnaire Long Form for measure walking and cycling for transport and the Neighborhood Environment Walkability Scale Abbreviated. Furthermore, perceived proximity from home to public open spaces and shopping centers was assessed.  Perceived land use mix access (OR: 1.32; 95%CI: 1.16,1.50) and the existence of many alternative routes in the neighbourhood (1.09 1.01,1.17) were associated with higher odds of reporting any walking for transport =10 min/week) Perceived slow speed of traffic (1.88 1.82,1.93) and few drivers exceeding the speed limits (1.92; 1.86,1.98) were also related to higher odds of reporting any walking for transport. The odds of reporting any cycling for transport =10 min/week) were higher in participants perceiving more walking/cycling facilities (1.87 1.76,1.99) and better aesthetics (1.22 1.09,1.38)  Dissimilar perceived neighborhood built environment characteristics were associated with walking and cycling for transport among inhabitants from Latin America.
A quantification of lower limb coordinative variability during running with different levels of midsole cushioning
Venue: Footwear Science
Year: 2019

Cushioned material between the foot and the ground during the stance phase of running dampens haptic feedback information used by higher control centres to inform subsequent movement executions. The purpose of this investigation was to examine whether this constraint on the motor system would manifest in reduced coordinative variability in lower limb joint couplings and a more 'rigid' gait pattern, implying increased consistency of tissue stress during time periods of limb loading. Ten midfoot and 10 rearfoot experienced distance runners, all of whom were habitual in their categorized footstrike pattern and free of any pain or injury, ran on a treadmill while barefoot and in shoes with minimalist (New Balance Minimus) and maximalist (Hoka Stinson One One) amounts of midsole cushioning. No differences in leg segment coordinative variability were observed between footwear conditions in either group of runners. Peaks in variability were often observed around periods of gait transition, primarily in foot shank couplings. Further, a novel observation was the altered spatiotemporal properties of the segments' phase plots between footwear conditions, manifesting in altered joint coupling patterns. The effect of increased midsole cushioning material on proprioceptive acuity during stance was not a sufficient disturbance to the motor system to manifest in altered levels of coordinative variability. Healthy, experienced runners likely display learned coordination patterns containing 'normal' levels of variability. Preliminary observations of altered joint coupling patterns between footwear conditions may have significant implications for healthy mechanical function. Prospective investigations should be employed to assess for any association between injury risk and individual specific levels of coordinative variability.
Corporate social responsibility and decision analysis in a supply chain through government subsidy
Year: 2019

With rapid economic development, related social issues have become more prominent than before. How to effectively encourage enterprises to undertake more corporate social responsibility (CSR) and maintain the sustainable development of society has become an urgent task for managers and researchers to resolve. With respect to decision problems of a retailer dominated supply chain considering CSR under government subsidy, based on game analysis technology, we establish a three stage Stackelberg game model that consists of the government, a dominant retailer and n suppliers, and exploit it for analyzing the optimal decisions either with or without government subsidy, and explore the impact of the government subsidy on the profits of the members of the supply chain, the CSR effort level and social welfare in the retailer dominated supply chain, and determine the relationship between the optimal government subsidy rate and CSR level. Our results show that the higher the effort level is, the more positive effect on the profits the whole supply chain experiences. Compared with those situations under non government subsidies, a certain range of government subsidies can promote the supply chain members to undertake CSR and improve overall performance of the supply chain and the welfare of the society.
APOBEC and ADAR deaminases may cause many single nucleotide polymorphisms curated in the OMIM database.
Venue: Mutation research
Year: 2018

Cytosine and adenosine deamination events (DNA, RNA substrates) account for most codon context Targeted Somatic Mutation (TSM) patterns observed in immunoglobulin (Ig) somatic hypermutation (SHM) and in cancer exomes following Ig SHM like responses. TSM refers to the process of somatic mutagenesis involving deamination events that results on a dominant type of mutation (e.g. C to T) and co incident at a particular motif (e.g. WRC) and preferentially targeting the first, second or third nucleotide position within the mutated codon (e.g. MC1, MC2 or MC3, read 5 prime to 3 prime) It is now widely accepted that if left uncorrected, the accumulation of uncorrected TSMs involving the deaminases, may lead to a diagnosis of cancer or other degenerative disease. Our hypothesis is that many missense, nonsense and synonymous single nucleotide polymorphisms (SNPs) associated with clinically significant diseases may have arisen in the population by similar highly targeted deamination events. The OMIM database was searched for disease associated SNPs on the X chromosome, and for all chromosomes. The nucleotide substitution patterns for disease associated SNPs were analyzed by the TSM method to identify the likely deaminase source for C to U (C to T/G to A) and A to I (A to G/T to C) derived gene mutations preferentially targeting known sequence motifs associated with the deaminases: AID, APOBEC3G, APOBEC3B and ADAR 1/2. Of the 789 OMIM SNPs analysed. In both data sets, the mutation targeting preferences within the mutated codon reveal a statistically significant bias (p 0.001) The results imply that a deamination of C site and A site targets are written into the human germline for the chromosome wide exomic SNPs analysed. This is consistent with previously observed mutation patterns arising in cancer genomes and hypermutated Ig genes during SHM. The results imply that similar types of deaminase mediated molecular processes that occur in somatic hypermutation and cancer, may be contributing causative drivers of human exomic SNPs.
Gate Drivers for Medium Voltage SiC Devices
Venue: IEEE Journal of Emerging and Selected Topics in Industrial Electronics
Year: 2021

Extensive research in wide bandgap material technology such as silicon carbide (SiC) has led to the development of medium voltage (MV) power semiconductor devices with blocking voltages of 3.3 to 15 kV. When these devices are used in various applications, they are exposed to a high peak voltage stress and a very high $dv/dt$ (50 100 V/ns) These impose stringent requirements on the gate driving stage for these devices in terms of featuring a high isolation voltage capability along with a high $dv/dt$ ruggedness, which makes it necessary to have an ultralow coupling capacitance between primary and secondary sides of the gate drivers. One of the key issues in achieving this MV insulation pertains to the necessary clearance and creepage requirements, as defined in IEC 61800 5 1 standards. While the successful operation of these gate drivers is demonstrated in MV converter applications such as solid state transformers, and MV grid connected inverters, substantial research needs to be carried out to improve the gate drivers' performance and provide a plug and play solution. This article aims to comprehensively review these gate drivers and consolidate various required design features concerning their galvanic isolation stage, based on normal and short circuit operation of MV high power converter systems. Different device short circuit protection schemes for these gate drivers are explored in detail. Additional applications and functionalities of the gate drivers, including gate drivers used in the series connection of MV devices and intelligent gate drivers, are also provided in brief. Based on prior research, this review aims to provide design choices and guidelines for the gate drivers, accelerating the growth and deployment of MV SiC devices for field applications.
Natural Language Processing: State of The Art, Current Trends and Challenges
Venue: ArXiv
Year: 2017

Natural language processing (NLP) has recently gained much attention for representing and analysing human language computationally. It has spread its applications in various fields such as machine translation, email spam detection, information extraction, summarization, medical, and question answering etc. The paper distinguishes four phases by discussing different levels of NLP and components of Natural Language Generation (NLG) followed by presenting the history and evolution of NLP, state of the art presenting the various applications of NLP and current trends and challenges.
Reflections on self determination theory as an organizing framework for personality psychology: Interfaces, integrations, issues, and unfinished business.
Venue: Journal of personality
Year: 2019

This special issue focuses on self determination theory (SDT) as an integrative framework for the wider field of personality research. In this commentary our aims include: reflecting on the utility and strengths of SDT as such a general framework and responding to the various contributions in this issue regarding their use of SDT as a guiding, complementary, or contrasting framework.  We describe how SDT has developed organically and conservatively from "within" based on the emerging patterns of evidence, as well through the ongoing challenges from other models and frameworks. We then discuss each of the various contributions to this special issue, addressing themes that include SDT's breadth of methods, and its relevance to topics such as narcissism, wisdom, individual differences, Big Five traits, and the neuropsychology of motivation, among others. Across these discussions, we highlight fruitful avenues for research and cross fertilization across the fields of personality, development, motivation, and neuroscience. At the same time, we counter some claims made about SDT, and forward certain cautions regarding the integration of SDT and other personality frameworks and models.  We conclude by revisiting the value of broad theory, and SDT in particular, for coordinating complex research findings concerning motivation, personality development and wellness across multiple levels of analysis and, perhaps more importantly, for pointing researchers to the right questions within today's prolific empiricism.
Identification in organization: Role of individuals self concept orientation and identification motives
Year: 2013

The self concept orientation of individuals to achieve multiple targets of organization identification coworker, workgroup and organizational identification is evaluated with mediating role of individuals associated motives. The study sample is consisted of 74 educational specialists from renowned universities of Pakistan. Result shows that, Self concept orientation has a positive but insignificant impact (R2 =0.023, b=0.121, P=0.199) on organization identification targets. Self motives of individuals positively but partially mediates between self concept orientation and organizational identification targets (R2 =0.004, b=0.052, P=0.59) The overall result supports the view that associated motives; self consistency, self enhancement and self expansion play an intervening role in individuals' self concept orientation to identifying organizational targets.  Identification, motives, self orientation.
Curcumin A Viable Agent for Better Bladder Cancer Treatment
Venue: International journal of molecular sciences
Year: 2020

Although the therapeutic armamentarium for bladder cancer has considerably widened in the last few years, severe side effects and the development of resistance hamper long term treatment success. Thus, patients turn to natural plant products as alternative or complementary therapeutic options. One of these is curcumin, the principal component of Curcuma longa that has shown chemopreventive effects in experimental cancer models. Clinical and preclinical studies point to its role as a chemosensitizer, and it has been shown to protect organs from toxicity induced by chemotherapy. These properties indicate that curcumin could hold promise as a candidate for additive cancer treatment. This review evaluates the relevance of curcumin as an integral part of therapy for bladder cancer.
Microsoft COCO: Common Objects in Context
Venue: ECCV
Year: 2014

We present a new dataset with the goal of advancing the state of the art in object recognition by placing the question of object recognition in the context of the broader question of scene understanding. This is achieved by gathering images of complex everyday scenes containing common objects in their natural context. Objects are labeled using per instance segmentations to aid in precise object localization. Our dataset contains photos of 91 objects types that would be easily recognizable by a 4 year old. With a total of 2.5 million labeled instances in 328k images, the creation of our dataset drew upon extensive crowd worker involvement via novel user interfaces for category detection, instance spotting and instance segmentation. We present a detailed statistical analysis of the dataset in comparison to PASCAL, ImageNet, and SUN. Finally, we provide baseline performance analysis for bounding box and segmentation detection results using a Deformable Parts Model.
Optimal excess of loss reinsurance contract with ambiguity aversion in the principal agent model
Venue: Scandinavian Actuarial Journal
Year: 2019

We discuss an optimal excess of loss reinsurance contract in a continuous time principal agent framework where the surplus of the insurer (agent/he) is described by a classical Cramer Lundberg (C L) model. In addition to reinsurance, the insurer and the reinsurer (principal/she) are both allowed to invest their surpluses into a financial market containing one risk free asset (e.g. a short rate account) and one risky asset (e.g. a market index) In this paper, the insurer and the reinsurer are ambiguity averse and have specific modeling risk aversion preferences for the insurance claims (this relates to the jump term in the stochastic models) and the financial market's risk (this encompasses the models' diffusion term) The reinsurer designs a reinsurance contract that maximizes the exponential utility of her terminal wealth under a worst case scenario which depends on the retention level of the insurer. By employing the dynamic programming approach, we derive the optimal robust reinsurance contract, and the value functions for the reinsurer and the insurer under this contract. In order to provide a more explicit reinsurance contract and to facilitate our quantitative analysis, we discuss the case when the claims follow an exponential distribution; it is then possible to show explicitly the impact of ambiguity aversion on the optimal reinsurance.
Patient interpersonal factors and the therapeutic alliance in two treatments for bulimia nervosa
Venue: Psychotherapy research journal of the Society for Psychotherapy Research
Year: 2008

Although the therapeutic alliance is robustly associated with psychotherapy outcomes, less is known about factors that influence its development. This study examined the association between baseline patient interpersonal factors and patient rated alliance in a randomized trial comparing cognitive behavioral therapy (CBT) and interpersonal therapy (IPT) for bulimia nervosa. Using hierarchical linear modeling, early and middle alliance were negatively associated with interpersonal distress and positively associated with interpersonal affiliation. Middle alliance was also related to treatment group interactions with rigidity, affiliation, and control. Overall, alliance growth was higher in IPT than CBT. Using group based trajectory analysis, three divergent alliance trajectories emerged (high and improving, low and improving, and low and stable) with group mean differences between two of them in terms of interpersonal distress and hostile submissiveness.
Examination of acetabular labral tear: a continued diagnostic challenge
Venue: British Journal of Sports Medicine
Year: 2013

Acetabular labrum tears (ALT) are present in 22 55% of individuals with hip or groin pain. Tears can occur as a result of trauma or degeneration and are markedly associated with femoral acetabular morphological variations. An ALT can lead to biomechanical deficiencies and a loss of stability to the coxafemoral joint due to the labrum serving as a stabilising structure of this joint. The diagnosis of ALT is complex and multidimensional. Although tremendous improvements in diagnostic utility for ALT have occurred in the past 25 years, there are few patient history, clinical examination and special test findings that are unique to the condition. Imaging methods such as MRI, CT and ultrasonography have demonstrated reasonable accuracy, but not at a level that allows use as a stand alone measure. Outcomes measures that focus on functional limitation or that are used to measure recovery should envelop the complexities of the condition and be captured using both self report and physical performance measures. Only when patient history, objective testing, clinical examination special testing and imaging are combined can a clinician fully elucidate the multidimensional diagnosis of ALT.
Talent Management recommendations for SME based on Large Enterprise analysis
Year: 2015

As a greater globalized world motivates companies to expand beyond their national borders, the need for finding suitable talent is higher than ever before. Technological advancements, industrial innovation and even political atmospheres can lead to shifting markets, which makes the need for strategic talent management plans more prominent. It is therefore reasonable to expect that small and medium sized enterprises (SME) will have different talent management (TM) methods than larger enterprises. Additionally, it is reasonable to predict SME and large enterprises will each have their own unique struggles to TM. A large international corporation was therefore analyzed and lessons were drawn from the case study in order to formulate recommendations for the small Czech company, Prazska cokolada. This master thesis poses the following hypotheses: 1. SMEs can adopt talent management practices from large enterprises, by which they increase their efficiency. 2. Czech SMEs will benefit from providing robust career opportunities and incentives, because these practices increase talent retention.
Rethinking Immigration as a Controversy.
Year: 2018

Banning refugees. Building a wall along the U.S. Mexico border. Separating children from their parents. Detaining and deporting immigrants at higher rates. Immigration is front page news. While immigration has historically been a divisive issue in the United States,1 debates surrounding immigrants particularly those from Latin America, the Caribbean, and Muslim majority countries have intensified.2 Moreover, presidential policy decisions that have momentous consequences for minoritized groups and, more broadly, for U.S. society are currently being implemented. As the U.S. and other nations grapple with the boundaries of inclusion at a time of increasing political polarization, teachers face quandaries about how to address immigration in classrooms. Although some educators may avoid immigration as a discussion topic,3 others enthusiastically choose it precisely because of its  Further complicating decisions about whether and how to teach about immigration is the question of who is in the classroom. Under the U.S. Supreme Court ruling in Plyler v. Doe (1982) undocumented students have the right to attend pub