nils-herrmann/clean_scirepeval huggingface dataset:
The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III
Venue: Acta naturae
Year: 2014

A mechanism for the induction of programmed cell death (apoptosis) upon dysfunction of the mitochondrial respiratory chain has been studied. Previously, we had found that inhibition of mitochondrial cytochrome bc1, a component of the electron transport chain complex III, leads to activation of tumor suppressor p53, followed by apoptosis induction. The mitochondrial respiratory chain is coupled to the de novo pyrimidine biosynthesis pathway via the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) The p53 activation induced in response to the inhibition of the electron transport chain complex III has been shown to be triggered by the impairment of the de novo pyrimidine biosynthesis due to the suppression of DHODH. However, it remained unclear whether the suppression of the DHODH function is the main cause of the observed apoptotic cell death. Here, we show that apoptosis in human colon carcinoma cells induced by the mitochondrial respiratory chain complex III inhibition can be prevented by supplementation with uridine or orotate (products of the reaction catalyzed by DHODH) rather than with dihydroorotate (a DHODH substrate) We conclude that apoptosis is induced in response to the impairment of the de novo pyrimidine biosynthesis caused by the inhibition of DHODH. The conclusion is supported by the experiment showing that downregulation of DHODH by RNA interference leads to accumulation of the p53 tumor suppressor and to apoptotic cell death.
Psycholinguistic Aspects of the Semantic Field of the Concept "War" in Modern Media Space
Year: 2018

This paper presents modern trends in the change of the semantic field of the concept "war" Based on the analysis of mass media in Russia, Ukraine and the USA, we demonstrated the regularities and interdependences of the mass media content and changes in the conceptual worldview of the people that consume information. We underlined the link between the changes in the forms of international conflicts and the increase of the units contributing to the semantic field of the concept "war" We analised how the information and communicative space effects the change of the conceptual (mental, cognitive) worldview of the public. Analysis of the semantic compatibility of the features of the concept "war" in mass media has revealed that apart from the military and armament themes, it contains the semantic units related to informational and psychological tools of influence. In the result of the systematic application of the concept "war" in relation to such semantic units as "informational" "psychological" "cyber" "hybrid" "fake news" "sanctions" etc. there takes place a fixation of compatibility of new semantic units with the concept "war" The broadening of the extent of the concept occurred due to the addition of two objects: "informational virtual component" comprising informational and psychological spheres of influence as well as a <technological component" on which the informational security of the state is based. Thus, the modern extent and intent of the concept "war" includes not only academic dictionary definitions, but also the definitions that refer to the involvement of tools and techniques aimed at the securing an armless victory in the confrontation. The findings of the research also demonstrated a certain difference in the development of the concept in Ukrainian, western and pro Russian mass media. While "war" in the pro Russian mass media is covered in connection with an open aggression accompanied by the use of weapons, this concept in Ukrainian and western mass media is used in relation to psychological and information influence. Thus, at the current stage, the broadening of the extent of the concept "war" has taken place, which is interrelated with the expansion of the semantic field, and is reflected in the change in the conceptual picture of the world within this concept.
Hypertext Transfer Protocol (HTTP/1.1) Activity Identifiers
Year: 2019

It is very common that implementers of HTTP severs require the ability to associate an identifier to an HTTP request and or response, this can be for a number of reasons which could include checking for duplicate requests, allowing the caller of an API to maintain a record of their interaction with the server or to track client/server requests through a disparate system of services. In any case, the implementer will quite often use a custom HTTP header and either assign a value itself or require the caller to supply the value. This document outlines a consistent storage mechanism for this identifier by way of a standard HTTP header and a new status code for when a mandated identifier is omitted. The purpose is to create better consistency for clients of third party HTTP servers and HTTP based APIs by introducing this standard request and response header.
Three way decisions based on neutrosophic sets and AHP QFD framework for supplier selection problem
Venue: Future Gener. Comput. Syst.
Year: 2018

The neutrosophic set is an excellent tool for dealing with vague and inconsistent information effectively. Consequently, by studying the concept of three way decisions based on neutrosophic set, we can find a suitable manner to take a reasonable decision. In this article, we suggest two rules of three way decisions based on three membership degrees of neutrosophic set. A new evaluation function is presented to calculate weights of alternatives, for choosing the best one. We also study a supplier selection problem (selecting suppliers to obtain the indispensable materials for assisting the outputs of companies) The best suppliers need to be selected to enhance quality, service, to reduce cost, and to control time. The most widely used technique for determining the requirements of a company is the Quality Function Deployment (QFD) Since traditional QFD technique does not prioritize stakeholders' requirements and fails to deal with vague and inconsistent information, this research also integrates it with Analytic Hierarchy Process (AHP) depending on neutrosophic environment. A case study is presented to illustrate the effectiveness of the proposed model.
1.55 mm pulse coherent LIDAR with 10 km detection range
Venue: Optical Engineering
Year: 2019

Recently, a 1.55 mm pulsed coherent Doppler LIDAR system using all fiber optical components was developed to achieve real time measurements of wind fields. The system employs 100 mJ pulse energy at 10 kHz pulse repetition rate. In addition, the system consists of a fiber based optical transceiver unit, a two axis scanner, and a multicore digital signal processor (DSP) for real time signal processing. With compact and mobile design, the LIDAR is easy to transport and deploy for different field campaigns. For a different application of LIDAR, the range resolution can change manually. A horizontal detection range of 10 km is achieved with the temporal and spatial resolution of 1 s and 30 m, respectively. Field experiments compared with an anemometer show that correlation coefficient of the different wind speed measurements is 0.953; the correlation coefficient for wind direction values is 0.967. Continuous wind profiles of the planetary boundary layer are presented to demonstrate the stability of the system.
High speed resistive switching in Pt/TiO2/TiN film for nonvolatile memory application
Year: 2007

We have fabricated and investigated the bipolar resistive switching characteristics of Pt/rutile TiO2/TiN devices for resistance memory applications. Data writing for five level resistance states has been demonstrated by varying the amplitude of 5ns voltage pulses. In addition, data retention of more than 256h at 85degC and an excellent endurance of over 2x106cycles have been confirmed. These results indicate that Pt/TiO2/TiN devices have a potential for nonvolatile multiple valued memory devices.
Prefrontal Parvalbumin Neurons in Control of Attention
Venue: Cell
Year: 2016

While signatures of attention have been extensively studied in sensory systems, the neural sources and computations responsible for top down control of attention are largely unknown. Using chronic recordings in mice, we found that fast spiking parvalbumin (FS PV) interneurons in medial prefrontal cortex (mPFC) uniformly show increased and sustained firing during goal driven attentional processing, correlating to the level of attention. Elevated activity of FS PV neurons on the timescale of seconds predicted successful execution of behavior. Successful allocation of attention was characterized by strong synchronization of FS PV neurons, increased gamma oscillations, and phase locking of pyramidal firing. Phase locked pyramidal neurons showed gamma phase dependent rate modulation during successful attentional processing. Optogenetic silencing of FS PV neurons deteriorated attentional processing, while optogenetic synchronization of FS PV neurons at gamma frequencies had pro cognitive effects and improved goal directed behavior. FS PV neurons thus act as a functional unit coordinating the activity in the local mPFC circuit during goal driven attentional processing.
AirNet: Neural Network Transmission over the Air
Venue: ArXiv
Year: 2021

State of the art performance for many emerging edge applications is achieved by deep neural networks (DNNs) Often, these DNNs are location and time sensitive, and the parameters of a specific DNN must be delivered from an edge server to the edge device rapidly and efficiently to carry out time sensitive inference tasks. We introduce AirNet, a novel training and analog transmission method that allows efficient wireless delivery of DNNs. We first train the DNN with noise injection to counter the wireless channel noise. We also employ pruning to reduce the channel bandwidth necessary for transmission, and perform knowledge distillation from a larger model to achieve satisfactory performance, despite the channel perturbations. We show that AirNet achieves significantly higher test accuracy compared to digital alternatives under the same bandwidth and power constraints. It also exhibits graceful degradation with channel quality, which reduces the requirement for accurate channel estimation.
Using IoT in Supply Chain Management
Year: 2020

Supply chain management has been alive and has developed overpast hundred years. This report takes a detail account of improvementhistory of the availability chain administration. A review of the literaturereveals that over the years the traditional supply chainmanagement,which relied on manual and laborious gathering of dataand tracking ofproducts, has evolved in to Smart supply chainmanagement. Startingfrom simple RFID based tagging foridentification of products, the eventof sensor based technologies andcommunicating devices has occupyyourself an massive role within theoverall increase of the smart supplychains. It is understood that anentire lot of Iot infrastructure layeroperates by gathering,interactive the knowledge to trace the position,quality and opportunedelivery of products. The use of IoT today notonly tracks theproducts but intelligently gives minute about produce situation andhelps in defending and plummeting losses
PENGARUH PEMBERIAN EPINEPRIN DAN HIDROKORTISON TERHADAP JUMLAH DAN DIAMETER GERMINAL CENTER KELENJAR GETAH BENING TIKUS PUTIH JANTAN WISTAR
Year: 2008

Stress is a non specific respone of body if the deman of body increase cause a stressor. Stress will increase sympathetic activity with releasing apinephrine and cortisol. Releasing apineprhine and cortisol to long time will reducing imunity system. Stress can reducing lymphosit B expression, but are this response include exchange of amount and diameter of center germinal in lymph node. This research is to purpose to find out epinephrine and cortisol administration make reducing of amount and diametre center germinal of lymph node. Sample in this research are 20 rattus norvegiccus Wistar, divided to 4 group, they are control that administrated NaCl, first experiment administrated epinefrin, second experiment administrated hidrokortisone, and third experiment administrated both epinephrine and hidrocortishone. The sampling technique is simple random sampling, and collecting data taken from lymph node histologic preparation and then observed with ray microscope. The research resulting significance score is 0,000 (p<0,05) to anova test, and LSD test is resulting score of controle with epinephrine is 0,006, controle with cortisol is 0,003, and controle with both epinephrine and cortisol is 0,000 for center germinal amount, and then for diametre between controle with epinephrine is 0,132, controle with cortisole is 0,22, and control with both epinefrin and cortisol is 0,002. Conclude the research is epinephrine and cortisol administration are reducing amount and diametre center germinal of lymph node rattus norvegiccus Wistar.
Efficient elastic reverse time migration for the decomposed P wavefield using stress tensor in the time domain
Year: 2015

To obtain accurately migrated image in elastic media, wavefield decomposition is needed. In particular, conventional decomposed P wavefield is obtained by using divergence operator. Because stress tensor can be formulated by space differentiated displacement, in this paper, it was used to decompose P wavefield. And absolute value function was applied to decomposed P wavefield with stress tensor for acquisition of identical polarity of upand down going wavefield. Using these approaches, we developed two types of migration algorithms. To examine feasibility of our migration algorithms, we carried out the numerical tests. Through these results, we can obtain reasonable migrated images by using our imaging conditions.
Iranian EFL Learners' Willingness to Communicate and Language Learning Orientations
Year: 2014

Willingness to communicate (WTC) has been defined as the intention to initiate communication, given a choice. It was speculated that orientations toward language learning would affect students' WTC in a foreign language (FL) Being that, Urmia university students, living in a somewhat multilingual community, participated in the current study. Be that as it may, questionnaires on WTC inside and outside the classroom and the questionnaire on language learning orientations adapted from MacIntyre, et al. (2001) were put to good use for the purpose of collecting data. Hence WTC inside and outside the classroom was measured in each of four skill areas: speaking, writing, reading, and comprehension. Alternatively, five orientations or causes of studying a FL were investigated: travel, job related, friendship, personal knowledge, and school achievement. Under those circumstances, results revealed that application of all five orientations for language learning was poorly correlated with WTC both inside and outside the classroom. Moreover, job related orientation scores were weakly correlated with WTC outside the classroom contrary to expectations. Given these points, it would come to light that stronger orientations for language learning tend to be more favorably related to WTC inside than outside the classroom.
Patient motion tracking for non isocentric and non coplanar treatments via fixed frame of reference 3D camera
Venue: Journal of applied clinical medical physics
Year: 2020

As C arm linac radiation therapy evolves toward faster, more efficient delivery, and more conformal dosimetry, treatments with increasingly complex couch motions are emerging. Monitoring the patient motion independently of the couch motion during non coplanar, non isocentric, or dynamic couch treatments is a key bottleneck to their clinical implementation. The goal of this study is to develop a prototype real time monitoring system for unconventional beam trajectories to ensure a safe and accurate treatment delivery.  An in house algorithm was developed for tracking using a couch mounted three dimensional (3D) depth camera. The accuracy of patient motion detection on the couch was tested on a 3D printed phantom created from the body surface contour exported from the treatment planning system. The technique was evaluated against a commercial optical surface monitoring system with known phantom displacements of 3, 5, and 7 mm in lateral, longitudinal, and vertical directions by placing a head phantom on a dynamic platform on the treatment couch. The stability of the monitoring system was evaluated during dynamic couch trajectories, at speeds between 10.6 and 65 cm/min.  The proposed monitoring system agreed with the ceiling mounted optical surface monitoring system in longitudinal, lateral, and vertical directions within 0.5 mm. The uncertainty caused by couch vibration increased with couch speed but remained sub millimeter for speeds up to 32 cm/min. For couch speeds of 10.6, 32.2, and 65 cm/min, the uncertainty ranges were 0.27 0.73 mm, 0.15 0.87 mm, and 0.28 1.29 mm, respectively.  By mounting a 3D camera in the same frame of reference as the patient and eliminating dead spots, this proof of concept demonstrates real time patient monitoring during couch motion. For treatments with non coplanar beams, multiple isocenters, or dynamic couch motion, this provides additional safety without additional radiation dose and avoids some of the complexity and limitations of room mounted systems.
Discursive Strategies of Verbal Violence in the Users Comments on Facebook News Updates
Venue: Jurnal Ilmiah Peuradeun
Year: 2019

This article explores how verbal violence on Facebook was performed by the users. It investigates the discursive strategy exploited by them. The data of verbal violence were taken from user comments to news update posted on Indonesian news portal fans pages under the topic of Paris tragedy. The comments were taken from four different Indonesian news fans pages, namely Detik.com, Kompas.com, Liputan6.com and Tribunnews.com. The collected data were analyzed qualitatively. Applying Discourse Historical Approach (DHA) proposed by Wodak, the result shows that the users exploits three strategies to perform verbal violence namely referential strategy, predicative strategy and argumentation strategy. Employing referential strategy, verbal violence is realized in the form of noun and noun phrase, which functions as subject, object and modifier of noun phrase. Employing predicative strategy, verbal violence is realized in the form of word, phrase and clause, which function as attribute or predicate. Employing argumentation strategy, verbal violence is realized in the form of sentence and discourse.
Analysis of apocarotenoid volatiles during the development of Ficus carica fruits and characterization of carotenoid cleavage dioxygenase genes.
Venue: Plant science an international journal of experimental plant biology
Year: 2020

In plants the oxidative cleavage of carotenoid substrates produces volatile apocarotenoids, including b ionone, 6 methyl 5 hepten 2 ol, and a ionone; these compounds are important in herbivore plant communication. Combined chemical, biochemical, and molecular studies were conducted to evaluate the differential accumulation of carotenoids and volatile apocarotenoids during the development of pollinated and parthenocarpic fig fruits. Pollinated fig fruits showed less emission of apocarotenoid volatiles than the parthenocarpic figs, while in the case of carotenoid pigments, pollinated figs manifested higher accumulation. The apocarotenoids, 6 methyl 5 hepten 2 ol and b cyclogeraniol, showed a marked increase after the two weeks of hand pollination in pollinated and parthenocarpic figs; but afterwards these volatile levels decreased during further fruit development. In addition, we report a transcriptome based identification and functional characterization of the carotenoid cleavage dioxygenase (FcCCD) genes. These genes were overexpressed in Escherichia coli strains previously engineered to produce different carotenoids. The recombinant FcCCD1A enzyme showed specificity for the 9,10 (9',10' double bond position of cyclic carotenoids to generate a ionone and b ionone, while FcCCD1B cleaved lycopene and an acyclic moiety of d carotene, producing 6 methyl 5 hepten 2 one. The qRT PCR analysis of FcCCD genes revealed differential gene expression during fig fruit development. Our results suggest a role for the FcCCD1genes in apocarotenoid biosynthesis in fig fruits.
A Review on Road Scene Image Enhancement
Year: 2016

Enhancement plays an important role in digital image processing.The visibility of images of open air road scenes becomes degraded when captured in severe climate conditions. Drivers frequently turn on the headlights of their vehicles and streetlights are regularly actuated, bringing about confined light sources in images of road scenes in these conditions. Furthermore, dust storms are additionally climate occasions that are regularly experienced when driving in a few districts. A novel and effective haze removal approach to cure these issues created by confined light sources and color shifts, which subsequently accomplishes better restoration results for single hazy images. Poor visibility degrades quality and performance of computer vision algorithms for smart transportation frameworks, for example, traveling vehicle data recorders and traffic surveillance systems, activity observation frameworks which must operate under a wide range of weather conditions. Another issue is that the captured foggy road scene images contains confined light sources or shading movement issues because of dust storm conditions. Movement detection and Darkness are also problems in the captured images. The goal of this work is to enhance the road scene images using different filters and enhancement techniques. The distinctive sorts of parameters are figured that are PSNR, MD, MSE and Processing Speeds.
An infinite Gaussian mixture model with its application in hyperspectral unmixing
Venue: Expert Syst. Appl.
Year: 2015

A new mixture model called IGMM is proposed to hyperspectral data.TSS is used to direct the trends of the number of Gaussian components.A Metropolis within Gibbs sampler is used for all the parameters. Spectral unmixing is a critical issue in multi spectral data processing, which has the ability to identify the constituent components of a pixel. Most of the hyperspectral unmixing current methods are based on Linear Mixture Model (LMM) and have been widely used in many scenarios. However, both the noise contained in the LMM and the requirement of essential prior knowledge strongly limit their practical applications. In order to address these issues, this paper proposes an iterative approach named CBIGMM. It utilizes infinite Gaussian mixture model to describe the hyperspectral data, which is robust to the noise due to the intrinsic randomness of the Gaussian components; and extracts the endmembers and their corresponding abundance in a fully unsupervised way without prior knowledge. A set of experiment is conducted on both synthetic and real data set from pesticide contaminated vegetables. The results and analyses show CBIGMM outperforms other methods in addressing hyperspectral unmixing problem.
TAC PHAM HOI KY "KHONG CO THAN THOAI" CUA LEE MYUNG BAK VA NHUNG CHIEU KICH HOFSTEDE TRONG VAN HOA DOANH NGHIEP HAN QUOC
Year: 2018

Hoi ky Khong co than thoai cua cuu Tong thong Lee Myung Bak, cuu Chu tich tap doan Hyundai co the xem la mot truong hop dai dien va dien hinh cho truyen ky ve cuoc doi nhung "nguoi hung" cua cac tap doan Han Quoc. Qua mot nhan vat xuat chung ma so phan gan bo voi su hinh thanh, phat trien mot trong nhung tap doan hang dau cua Han Quoc, Khong co than thoai giup chung ta cam hieu nguon suc manh da lam nen "ky tich song Han" tinh cach con nguoi va ban sac dan toc Han noi chung; dac diem van hoa doanh nhan, van hoa doanh nghiep Han Quoc noi rieng. Bai nghien cuu nay van dung cac chieu kich Geert Hofstede de tiep can lien nganh tim hieu van hoa doanh nghiep Han Quoc dua tren du lieu van hoc truyen ky doanh nhan.