nils-herrmann/clean_scirepeval huggingface dataset:
Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters Ce(III) fluoroprobe
Venue: Analytical and Bioanalytical Chemistry
Year: 2021

Herein, we synthesized and characterized glutathione capped copper nanoclusters (CuNCs) using a convenient one pot chemical reduction approach based on glutathione as capping and reducing agents. The Ce(III) induced aggregation induced emission of CuNCs to form a CuNCs Ce3+ fluoroprobe due to electrostatic and coordination interactions between Ce3+ and CuNCs. In contrast to CuNCs, the fluorescent intensities (FLs) of CuNCs Ce3+ were enhanced by 40 fold concomitant with 20 nm blue shift of the maximum emission, and a 3.45 fold lengthening of the average fluorescent lifetime. The FLs of CuNCs Ce3+ were selectively quenched at 650 nm by hydrogen peroxide (H2O2) via the redox reaction. Based on this phenomenon, the sensitive assay of H2O2 was realized, and the linear range spanned over the range of 14 140 mM. Notably, the visualization of the fluorescence quenched effect of H2O2 could be easily attained. Additionally, glucose could be specifically oxidized by glucose oxidase to produce H2O2, and thus the detection of glucose was achieved according to changes in the concentrations of H2O2. Under optimized conditions, the fluorescent assay of glucose based on the CuNCs Ce3+ system offered the linear range of 8 48 mM with detection limit of 2.4 mM. Meanwhile, high selectivity of the as constructed fluorescent assay allows the sensitive detection of H2O2 and glucose in real world care products and human serum samples, showing a great application potential in their conventional monitoring.
Ethics and evidence based practice
Year: 2015

Evidence based practice is roughly the use of current best evidence in making decisions about the care of patients (Sackett et al. 1996) At first it seems hard to imagine how such practice could raise ethical concerns; and yet it has. These concerns are set out in the first section of this chapter. Much of the past discussion of these problems has focused on the epistemology of evidence, with critics suggesting that EBP is based on an overly narrow definition of evidence and knowledge. This chapter tacks differently, focusing instead on the epistemology of practice; in other words, what type of evidence or knowledge is needed in deciding how to act? Using the distinction drawn by Aristotle between practical and scientific knowledge it is suggested that evidence in the form of scientific knowledge, no matter how widely defined, cannot form the basis for practice because it cannot provide the goals that action requires; for EBP these must be provided from within practice itself, for example, nursing or surgery. However, ultimately the goals are provided by wider personal and social goals, in particular, human flourishing. Once this is accepted, it is possible to resolve the ethical concerns that have been raised about EBP, drawing on Aristotle's account of reasoning in the practice areas of craft knowledge and of practical wisdom.
The wandering eye perceives more threats: Projection of attraction to alternative partners predicts anger and negative behavior in romantic relationships
Year: 2019

The current study tested the predictions that (a) people project their own attraction to alternative romantic or sexual partners onto their romantic partners and (b) this projection shapes anger and negative behavior toward romantic partners. These predictions were supported in a dyadic daily experiences study of 96 heterosexual romantic couples. Participants' self reported attraction to alternative partners predicted perceptions of the partner's interest independently of, and more strongly than, the partner's own self reported attraction, suggesting that participants projected their own extradyadic attraction onto their partners. Furthermore, this projection predicted perceivers' own anger and negative behaviors directed at their partners more strongly than did the partner's self reported attraction. Results suggest that participants were angry and antagonistic when they thought their partners were interested in alternative partners, but that this suspicion was a projection of their own attraction to alternatives more than it was an accurate reflection of their partner's attraction. Results suggest that projection of extradyadic attraction has an important influence on relationship quality and may exacerbate the negative relationship consequences of attraction to alternative partners.
Epoxy composite coating corrosion protection properties reinforcement through the addition of hydroxyl terminated hyperbranched polyamide non covalently assembled graphene oxide platforms
Year: 2020

This paper presents the role of GO particle functionalization by different contents of hydroxyl terminated hyper branched polyamide on the epoxy coating corrosion protection properties. Raman spectroscopy, UV visible analysis, and field emission scanning electron microscopy (FE SEM) methods were applied to study the HB/GO interactions and morphology at different ratios. Then, by electrochemical impedance spectroscopy (EIS) and accelerated corrosion test (salt spray) the Epoxy GO and Epoxy HB/GO 0.25, 0.5, 1.0 and 2.5 systems corrosion protection properties were investigated. Results obtained from Raman spectroscopy, UV Visible analysis, and FE SEM measurement proved that the GO sheets were successfully modified by HB molecules. SEM results evidenced that the GO particle dispersion quality in the epoxy matrix was significantly improved after modification by HB. Pull off results revealed significant improvement in the epoxy film adhesion to the steel surface in the presence of HB/GO. Results disclosed that the epoxy composite coating reinforced with HB/GO 0.5 and 1.0 showed the largest impedance >1010 ohm cm2) and lowest delamination values. Generally, the modified GO sheets significantly improved the epoxy coating corrosion protection properties due to the role of HB in improving the dispersion state (proved by SEM results) and interfacial interactions between the GO and epoxy matrix.
IDENTIFIKASI FAKTOR FAKTOR YANG MEMPENGARUHI DALAM PENGEMBANGAN USAHA KECIL DAN MENENGAH OTAK OTAK BANDENG BERBASIS POTENSI DAERAH DI KABUPATEN GRESIK
Year: 2018

Usaha kecil dan menengah (UKM) otak otak bandeng mempunyai peran penting sebagai salah satu penggerak perekonomian Kabupaten Gresik, karena dapat membantu dalam penyerapan tenaga kerja dan upaya pengentasan kemiskinan. Disisi lain, Usaha kecil dan menengah (UKM) otak otak Bandeng di Kabupaten Gresik mempunyai banyak permasalahan yang dihadapi antara lain: permodalan, pemasaran, produk tidak bisa tahan lama, proses produksi masih manual. Tujuan dari diadakan penelitian ini adalah untuk mengidentifikasi karakteristik UKM otak otak bandeng di Kabupaten Gresik agar dapat diketahui gambaran atau kondisi aktual yang dihadapi pelaku usaha UKM tersebut. Setelah mendapatkan gambaran atau kondisi aktual, maka dilakukan analisis kondisi lingkungan internal dan eksternal UKM otak otak bandeng dan pemilihan beberapa alternatif strategi pengembangannya. Kesimpulan dari penelitian ini adalah: Faktor faktor internal yang digunakan dalam mengembangkan UKM Otak Otak Bandeng di Kabupaten Gresik adalah: Bahan baku ikan bandeng berlimpah, Tanpa menggunakan bahan kimia dalam proses produksi, Produk sudah dikenal di masyarakat, Konsumsi ikan semakin meningkat, Produk tidak tahan lama, Sumber daya manusia masih rendah tingkat pendidikannya, Modal usaha kecil, Proses produksi masih manual, dan Terbatasnya akses pasar. Sedangkan Faktor faktor eksternal yang digunakan dalam mengembangkan UKM Otak Otak Bandeng di Kabupaten Gresik adalah: Dukungan kebijakan Pemerintah Daerah, Pertumbuhan jumlah penduduk semakin meningkat, Budaya membeli oleh oleh, Gresik sebagai kota wisata dan industri, Persaingan produk otak otak bandeng semakin ketat, Sulit mendapatkan ikan bandeng yang memiliki spesiikasi berat dan panjang yang ditentukan, Harga bahan baku fluktuatif, tetapi harga jual produk tetap, dan Manajemen keuangan belum teratur
Incidencia de sistemas agroforestales con Hevea brasiliensis (Willd. ex A.Juss. Mull;.Arg. sobre propiedades fisicas de suelos de lomerio en el departamento de Caqueta, Colombia
Year: 2015

Between April and July 2010, the effects of different agroforestry systems with rubber Hevea brasiliensis Muell) on the physical properties of soil in hilly area in the municipalities of Belen de los Andaquies, Florencia and El Doncello (Department of Caqueta, Colombia) were evaluated. H. brasiliensis Muell as monoculture and associated with fruit trees (SAF) and secondary vegetation (SAR) were compared against secondary forest (Bs) and native pasture (PNA) A completely randomized two factor design was arranged with five treatments (SAF, SAR, Mhe, Bs, and PNA) and two horizons (H A, H B) Relationships between physical variables between treatments were explored by using a principal component analysis, and the effect of agroforestry arrangements was assessed with a test of Monte Carlo. Compaction, real density and gravimetric moisture were similar (P> 0.05) in H A of Pna and Mhe. A positive significant effect (P <0.05) of H. brasiliensis Muell in bulk density, soil compaction and total porosity in H A of SAF and SAR systems compared with the same properties in Bs was found. In general, the incidence of agroforestry arrangements modifying soil physical variables in the Amazon piedmont was observed.
AN APPROACH FOR CRITICAL EVALUATION OF EXAMINATION QUESTIONS IN AN ENGINEERING FACULTY USING THE CLASSICAL BLOOM TAXONOMY
Year: 2018

Ideally, teaching curricula are designed to exude some learning behavioural outcomes in students. When students are examined through oral, practical and or theoretical evaluation schemes in examinations, the primary objective is to measure the relative extent to which students can exude the desired behavioural outcomes. Thus it is important that appropriate means and expressions are employed in assessment to measure learning. Based on an average occurrence rating scale, a set of Action verbs of the classical Bloom's taxonomy were used in this study in assessing the level of learning outcomes required in each of 21 Engineering Core Course examination questions used. Rates were computed for Knowledge, Comprehension, Application, Analysis, Synthesis and Evaluation levels of the Bloom's Taxonomy. Marginalized One Factor Statistical experiments and randomized two factor Statistical experiments were designed using the rates computed. Analysis of Variance (ANOVA) technique was used to test within and between treatments variations of the differences of means for the six Bloom's taxonomy levels using hypotheses at 0.05 levels of significance for each of the experimental design scenarios. Analyzed results show significant differences in course ratings at different Bloom taxonomy levels and significances in differences in ratings of the taxonomy for different courses. Group tests of hypotheses on differences of mean ratings for the courses show significance. The study brings to light the need for examiners in these courses to put more effort in upper levels of behavioural outcomes especially on Synthesis and Evaluation which are germane for training of good Engineers.  Learning outcomes, Bloom's taxonomy, Assessment, Synthesis and Evaluation, cognitive level, hierarchical systems
The Lepidoptera Odorant Binding Protein gene family: Gene gain and loss within the GOBP/PBP complex of moths and butterflies.
Venue: Insect biochemistry and molecular biology
Year: 2015

Butterflies and moths differ significantly in their daily activities: butterflies are diurnal while moths are largely nocturnal or crepuscular. This life history difference is presumably reflected in their sensory biology, and especially the balance between the use of chemical versus visual signals. Odorant Binding Proteins (OBP) are a class of insect proteins, at least some of which are thought to orchestrate the transfer of odor molecules within an olfactory sensillum (olfactory organ) between the air and odor receptor proteins (ORs) on the olfactory neurons. A Lepidoptera specific subclass of OBPs are the GOBPs and PBPs; these were the first OBPs studied and have well documented associations with olfactory sensilla. We have used the available genomes of two moths, Manduca sexta and Bombyx mori, and two butterflies, Danaus plexippus and Heliconius melpomene, to characterize the GOBP/PBP genes, attempting to identify gene orthologs and document specific gene gain and loss. First, we identified the full repertoire of OBPs in the M. sexta genome, and compared these with the full repertoire of OBPs from the other three lepidopteran genomes, the OBPs of Drosophila melanogaster and select OBPs from other Lepidoptera. We also evaluated the tissue specific expression of the M. sexta OBPs using an available RNAseq databases. In the four lepidopteran species, GOBP2 and all PBPs reside in single gene clusters; in two species GOBP1 is documented to be nearby, about 100 kb from the cluster; all GOBP/PBP genes share a common gene structure indicating a common origin. As such, the GOBP/PBP genes form a gene complex. Our findings suggest that (1) the lepidopteran GOBP/PBP complex is a monophyletic lineage with origins deep within Lepidoptera phylogeny, (2) within this lineage PBP gene evolution is much more dynamic than GOBP gene evolution, and (3) butterflies may have lost a PBP gene that plays an important role in moth pheromone detection, correlating with a shift from olfactory (moth) to visual (butterfly) communication, at least regarding long distance mate recognition. These findings will be clarified by additional lepidopteran genomic data, but the observation that moths and butterflies share most of the PBP/GOBP genes suggests that they also share common chemosensory based behavioral pathways.
Cancer Associated Thrombosis: A Two Way Street.
Venue: Seminars in thrombosis and hemostasis
Year: 2019

Pathological activation of the coagulation system occurs with virtually all forms of cancer, particularly epithelial malignancies. Accordingly, thrombosis is one of the most common comorbidities associated with cancer. Indeed, cancer associated thromboembolism is the second leading cause of death for cancer patients, second only to the cancer itself. The identification of specific molecular mechanisms whereby tumor cells activate the coagulation system and drive thrombosis has been an active area of investigation for several decades. Studies in animal models and human trials have revealed that there is a bidirectional relationship between coagulation factor activity and cancer, whereby the pathological hemostatic system activation associated with cancer not only promotes thromboembolism but also drives progression of the malignancy. Numerous studies indicate that factors up and down the clotting cascade can contribute to various stages of cancer, including tumorigenesis, primary tumor growth, and metastasis. Although there are some mechanistic points of commonality, there are also clearly context dependent contributions of coagulation components to cancer progression dependent on the type of cancer and stage of disease. It is also notable that in some instances, coagulation factors appear to contribute to cancer progression independently of their traditional roles in hemostasis and thrombosis. Here, the authors review the current state of the field with regard to hemostatic factor driven cancer pathogenesis.
Automated testing with targeted event sequence generation
Venue: ISSTA
Year: 2013

Automated software testing aims to detect errors by producing test inputs that cover as much of the application source code as possible. Applications for mobile devices are typically event driven, which raises the challenge of automatically producing event sequences that result in high coverage. Some existing approaches use random or model based testing that largely treats the application as a black box. Other approaches use symbolic execution, either starting from the entry points of the applications or on specific event sequences. A common limitation of the existing approaches is that they often fail to reach the parts of the application code that require more complex event sequences. We propose a two phase technique for automatically finding event sequences that reach a given target line in the application code. The first phase performs concolic execution to build summaries of the individual event handlers of the application. The second phase builds event sequences backward from the target, using the summaries together with a UI model of the application. Our experiments on a collection of open source Android applications show that this technique can successfully produce event sequences that reach challenging targets.
High flow nasal cannula oxygen therapy in children: a clinical review
Venue: Clinical and experimental pediatrics
Year: 2020

High flow nasal cannula (HFNC) is a relatively safe and effective noninvasive ventilation method that was recently accepted as a treatment option for acute respiratory support before endotracheal intubation or invasive ventilation. The action mechanism of HFNC includes a decrease in nasopharyngeal resistance, washout of dead space, reduction in inflow of ambient air, and an increase in airway pressure. In preterm infants, HFNC can be used to prevent reintubation and initial noninvasive respiratory support after birth. In children, flow level adjustments are crucial considering their maximal efficacy and complications. Randomized controlled studies suggest that HFNC can be used in cases of moderate to severe bronchiolitis upon initial low flow oxygen failure. HFNC can also reduce intubation and mechanical ventilation in children with respiratory failure. Several observational studies have shown that HFNC can be beneficial in acute asthma and other respiratory distress. Multicenter randomized studies are warranted to determine the feasibility and adherence of HFNC and continuous positive airway pressure in pediatric intensive care units. The development of clinical guidelines for HFNC, including flow settings, indications, and contraindications, device management, efficacy identification, and safety issues are needed, particularly in children.
Real Time Contingency Measures to Cope with Rainfall Variability in Southern Karnataka
Year: 2016

Real time contingency practices viz. selection of varieties, date of sowing, method of crop establishment, soil and moisture conservation practices were demonstrated in the Chikkamaranahalli cluster villages, Bengaluru rural district of Karnataka during 2011 to 2014. Selection of long duration variety (MR 1) for July sowing, medium duration (GPU 28) for August 1st fortnight and short duration (GPU 48) for August 2nd fort night performed better. In situ conservation moisture through opening of conservation furrow between paired rows of pigeonpea under finger millet pigeonpea (8: 2) and groundnut pigeonpea (8: 2) recorded significantly higher yields (2749 kg/ha and 1347 kg/ha, respectively) compared to farmers' practice. Among different methods of establishment in finger millet, transplanting recorded significantly higher grain yield (2461 kg/ha) and sowing of finger millet using modified bullock drawn seed drill recorded significantly higher yield (2417 kg/ha) compared to conventional method of broadcasting.
D Hologram in Futuristic Classroom A Review
Year: 2019

2018 Holography is a photographic method that records the light dispersed from a body and then produces a realistic image identified as three dimensional Holograms. The hologram reflects and transmits using a point source of incandescent light or two channel transmission hologram. In the world of education, 3D holograms can be integrated into mixed reality classrooms to ease the teaching and learning process. The significance of this application is to enable the 21st Century learners to experience the realistic content via 3D Holograms, thereby improving their learning curves. This paper highlights the fundamental concepts of hologram and discusses the diversified implementations of hologram as a mixed reality simulator in the futuristic classrooms. Recent technological advancements in the field of education and evidence from successful implementation of the mixed reality approach in educational research has also been debated. However, the application of Holograms in education is still confined within boundaries.
The Role of Interpersonal Influence in Counterbalancing Psychopathic Personality Trait Facets at Work
Year: 2018

The purpose of this study was to examine the relations of two facets of psychopathic personality (i.e. self centered impulsivity and fearless dominance) with interpersonally directed counterproductive work behavior (CWB I) and contextual performance (CP) Consistent with research on psychopathy, our hypothesis suggested that self centered impulsivity (i.e. behavioral impulsivity characterized by disregard for rules and responsibilities) would be positively related to CWB I and negatively related to CP. Using socioanalytic theory, we further suggested that fearless dominance (i.e. an egotistical personal style characterized by self promotion and prioritization of one's own needs before those of others) would be negatively associated with interpersonal performance (i.e. high CWB I and low CP) only when individuals indicated low levels of interpersonal influence (i.e. a dimension of political skill reflecting an ability to adapt one's behavior in subtle, sophisticated, and situationally effective ways) Results provided strong support for the differential relations of the psychopathic personality dimensions with the criteria of interest. Implications for theory, practice, and future research are provided in light of a number of notable strengths and limitations.
Ezetimibe added to statin therapy after acute coronary syndromes
Year: 2015

The median time weighted average LDL cholesterol level during the study was 53.7 mg per deciliter (1.4 mmol per liter) in the simvastatin ezetimibe group, as compared with 69.5 mg per deciliter (1.8 mmol per liter) in the simvastatin monotherapy group (P<0.001) The Kaplan Meier event rate for the primary end point at 7 years was 32.7% in the simvastatin ezetimibe group, as compared with 34.7% in the simvastatin monotherapy group (absolute risk difference, 2.0 percentage points; hazard ratio, 0.936; 95% confidence interval, 0.89 to 0.99; P 0.016) Rates of prespecified muscle, gallbladder, and hepatic adverse effects and cancer were similar in the two groups.  When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit.