nils-herrmann/clean_scirepeval huggingface dataset:
Potential of epigenetic therapies in non-cancerous conditions

There has been an explosion of knowledge in the epigenetics field in the past 20 years. The first epigenetic therapies have arrived in the clinic for cancer treatments. In contrast, much of the promise of epigenetic therapies for non-cancerous conditions remains in the laboratories. The current review will focus on the recent progress that has been made in understanding the pathogenic role of epigenetics in immune and inflammatory conditions, and how the knowledge may provide much needed new therapeutic targets for many autoimmune diseases. Dietary factors are increasingly recognized as potential modifiers of epigenetic marks that can influence health and diseases across generations. The current epigenomics revolution will almost certainly complement the explosion of personal genetics medicine to help guide treatment decisions and disease risk stratification.

Field of study: Biology
Constructing a Civic Community in Late Medieval London: The Common Profit, Charity and Commemoration. David Harry. Rochester, NY: Boydell Press, 2019. xii + 216 pp. $130.

fiscal-military state, private-public partnerships, Dutch ideas of property and possession, global capitalism, or what? They do not say, suggesting that past events were accidents of history rather than examples of processes. The authors are well read, so readers can certainly use the work as a foundation for their own further investigations by turning to the notes, which include many works in English. But digging is somewhat handicapped by the lack of a bibliography, and the index does not refer to the notes and lists only proper names (i.e., one can find “Benin, Bight of” and “Reformation,” but not “slavery” or “religion”).

Field of study: History
Hall measurements under weak persistent photoexcitation in Si-doped AlxGa1-xAs

The low-temperature Hall mobility of photoexcited electrons has been measured in Si-doped MBE AlGaAs samples. Different fractions of occupied DX centres were obtained by selecting different free-electron densities: possible systematic errors in Hall measurements due to the method of photoexcitation are demonstrated and critically analysed. Using suitable values for the acceptor density and the alloy scattering potential a fair fitting of the experimental data was achieved within both negative-U and positive-U models for the DX centre. Discrepancies between calculated and experimental mobility versus temperature curves are observed, which are more evident the lower the free-electron densities. They are tentatively explained as being due to electrons in an impurity band originated by the shallow effective-mass state related to the Gamma minimum of the conduction band.

Field of study: Materials science
Small shifts in microsite occupation could mitigate climate change consequences for mountain top endemics: a test analyzing saxicolous lichen distribution patterns

The extent to which small shifts among local topographic microsites could mitigate the effects of larger-scale climate change in arctic–alpine systems including mountain top organisms is largely unknown. This study is among the first to evaluate the relative contribution of microsite and altitude as a proxy for climate change on saxicolous lichen communities. We registered 107 lichen species in 54 boulders ranging from 900 to 2700 m.a.s.l. and in a large array of microsites in central Argentina. Communities ordinated along NMS multivariate analysis axes 1, 2 and 3 presented a cumulative R2 of 80%. The three axes were explained by altitude with axis 1 only being explained by altitude. Axis 2 was also explained by slope and aspect whereas axis 3 was explained by the interaction of altitude with aspect indicating that aspect was important only at lower altitudes but not at the mountain top. Lichen cover and richness were similar throughout the altitudinal gradient. We interpret that under a climate warming scenario, lower altitude species occupying pole ward facing slopes will have to migrate upwards while at the mountain top—for most communities—there still is scope for microsite segregation to compensate climate change.

Field of study: Environmental science
[Prediction of the changes of immunological status and psychopathological data in HIV-infected schizophrenia patients].

To predict the immunological status in HIV-infected patients with schizophrenia based on a set of clinical and psychopathological characteristics of the endogenous process.



The study included 28 patients with confirmed diagnosis of schizophrenia and HIV status. Authors used psychopathological method, along with psychometric scales (PANSS), in patients with schizophrenia and an immunological method for the determination of HIV-associated status and viral load.



Affective syndromes with severe depressive symptoms, volitional impairment, high impulsivity and social features of autism can be prognostically favorable factors for the immune status of HIV-infected patients with schizophrenia that obviously indicates an acute psychotic state. Negative (deficit) symptoms were prognostically unfavorable for the immune status of HIV-infected patients with schizophrenia and for psychosis course.



Favorable immune status corresponds to acute psychosis whereas the forms with severe deficit are associated with immunosuppression in HIV-infected patients.

Field of study: Medicine, Psychology
GLBM: A new QoS aware multicast scheme for wireless mesh networks

Wireless mesh networks (WMNs) have been attracting significant attention due to their promising technology. The WMN technology is becoming a major avenue for the fourth generation of wireless mobility. Communication in large-scale wireless networks can create bottlenecks for scalable implementations of computationally intensive applications. A class of crucially important communication patterns that have already received considerable attention in this regard are group communication operations, since these inevitably place a high demand on network bandwidth and have a consequent impact on algorithm execution times. Multicast communication has been among the most primitive group capabilities of any message passing in networks. It is central to many important distributed applications in science and engineering and fundamental to the implementation of higher-level communication operations such as gossip, gather, and barrier synchronisation. Existing solutions offered for providing multicast communications in WMN have severe restriction in terms of almost all performance characteristics. Consequently, there is a need for the design and analysis of new efficient multicast communication schemes for this promising network technology. Hence, the aim of this study is to tackle the challenges posed by the continuously growing need for delivering efficient multicast communication over WMN. In particular, this study presents a new load balancing aware multicast algorithm with the aim of enhancing the QoS in the multicast communication over WMNs. Our simulations experiments show that our proposed multicast algorithm exhibits superior performance in terms of delay, jitter and throughput, compared to the most well known multicast algorithms.

Field of study: Computer science, Engineering
Die Ermittlung der Hysteresegleichungen aus der komplexen Permeabilität und dem Klirrfaktor

ZusammenfassungDie Gleichungen vonRayleigh für die Hystereseschleifen werden so erweitert, daß der bei sehr kleinen Feldstärken beobachtete nichtlineare Zusammenhang zwischen Permeabilität und Feldstärke sowie zwischen Klirrfaktor und Feldstärke durch diese Gleichungen ebenfalls dargestellt wird. Die Äste der Hystereseschleife bleiben auch dann noch Parabeln, aber dieRayleigh-Konstantev muß durch eine Funktion der Maximalfeldstärke ersetzt werden. Dabei ist von besonderer Bedeutung, daß die komplexe Permeabilität in Abhängigkeit von der Maximalfeldstärke immer eineGerade als Ortskurve durchläuft.

Field of study: Physics
Combining Multi-class SVMs with Linear Ensemble Methods that Estimate the Class Posterior Probabilities

Roughly speaking, there is one main model of pattern recognition support vector machine, with several variants of lower popularity. On the contrary, among the different multi-class support vector machines which can be found in the literature, none is clearly favoured. On the one hand, they exhibit distinct statistical properties. On the other hand, multiple comparative studies between multi-class support vector machines and decomposition methods have highlighted the fact that each model has its advantages and drawbacks. These observations call for the evaluation of combinations of multi-class support vector machines. In this article, we study the combination of multi-class support vector machines with linear ensemble methods. Their sample complexity is low, which should prevent them from overfitting, and the outputs of two of them are estimates of the class posterior probabilities.

Field of study: Mathematics
über Molekülbildung im Zweierstoß. I

ZusammenfassungDas Ofenspektrum des Aluminiumhydrids zeigt, daß die Linien, die im Bogenspektrum fehlen, eine verstärkte Intensität haben. Diese Intensitätsanomalie hängt von folgenden Faktoren ab: 1. Von der Zeit, die vergangen ist, nachdem der Versuch begonnen worden war, 2. von der Temperatur im Ofen, 3. vom Druck im Ofen. Bei verhältnismäßig hoher Temperatur und hohem Druck tritt eine kontinuierliche Strahlung auf. Alle diese Effekte werden als Folge von Neubildung von A1H im1π-Zustand durch Zweierstoß gedeutet.

Field of study: Physics
The Influence on Jiangsu Economy While China Enter into FTA

Nowadays what influences will be resulted in owning to the Free Trade Areas which China are developing and constructing? Starting from the successful experience of another FTA in the world,as well as linking with the characteristic and superiority of Jiangsu economy,this paper makes a few suggestions as reference for the economy and trade of Jiangsu in order to larger the view of the development of economy.

Field of study: Economics
What are the Seasons

The concept of dividing the year into four seasons is reexamined to appraise critically the relative merit of two commonly used definitions of the seasons: 1) the astronomical definition, and 2) the meteorological breakdown into four three-month periods. These are compared with the definition of winter as the coldest season, summer as the warmest season, and spring and autumn as the transition seasons. Observational data on surface temperatures over the entire globe and, in particular, over the United States, are used to determine what the seasons should be. Presented here is an analysis of the amplitude, and phase of and percentage variance explained by the first harmonic of solar radiation at the top of the atmosphere and surface temperatures. Annual changes in surface temperature associated with the seasons are much larger over land than over the oceans. Surface temperatures lag the solar cycle by 27½ days over the United States, compared with 32½ days in mid-latitudes over the Northern Hemisp...

Field of study: Environmental science
Arbitrary Partial FEXT Cancellation in Adaptive Precoding for Multichannel Downstream VDSL

In this paper, we present and analyze a simplified, adaptive precoder for arbitrary partial far-end cross talk (FEXT) cancellation in the downstream of multichannel VDSL. The precoder is based on error signal feedback and is computationally efficient. Furthermore, the partial precoding makes it possible to operate the precoder at any desired complexity, and the system's performance increases with any increase in system complexity. Unlike previous works, in which each user experienced either complete FEXT cancellation or no cancellation at all, the presented precoder can mitigate the FEXT from any desired subset of interfering users for each user. We derive sufficient conditions for convergence of the adaptive precoder, for any partial cancellation scheme, and provide closed form steady state error analysis. The precoder's performance and convergence properties are also demonstrated through simulations.

Field of study: Engineering
Usefulness of Testing for Fecal Calprotectin in Pediatric Gastroenterology Clinical Practice

Gastrointestinal tract symptoms such as abdominal pain, constipation, diarrhea, and fever are common reasons for which parents take children to the pediatrician. An increasing prevalence of chronic diseases of the gastrointestinal tract and a decrease in the median age of their onset indicate the need to search for new diagnostic methods for differentiating inflammatory bowel diseases (IBDs) from other gastrointestinal tract diseases. An example of a novel biomarker is fecal calprotectin (FC), which is considered a noninvasive and useful marker of intestinal inflammation. This review summarizes currently available information on the use of FC in the diagnosis and monitoring of IBD in children. Additionally, it attempts to determine the course of action depending on the concentration of FC. Application of FC determination within the framework of primary medical care can decrease the number of children unnecessarily referred either to endoscopic or radiologic examination. There is a double advantage of calprotectin screening; for patients, it reduces delays in diagnosis and unnecessary exposure to endoscopy, and for doctors, it reduces pressure on endoscopy testing and facilitates decision-making. We emphasize the role of FC as a noninvasive marker, primarily in patients with IBD, in monitoring disease activity, predicting relapse, monitoring therapy efficacy, and monitoring postoperative relapses.

Field of study: Medicine
Microstructure and Properties of Nanostructured Coating on Ti6Al4V

Implant surface properties of Ti6Al4V alloy that is currently used as a biocompatible material because of a variety of unique properties can be improved by a self-organized TiO2 layer. The TiO2 nanotubes forming on the titanium-based materials is a relatively recent technology for the surface properties modification and represents pronounced potential in promoting cell adhesion, proliferation, and differentiation that facilitate an implant osseointegration. This work focuses on the influence of surface treatment quality and anodic oxidation parameters on the structure features and properties of TiO2 nanotube coatings. The nanotubes were formed on Ti6Al4V alloy substrates by simultaneous surface oxidation and controlled dissolving of an oxide film in the presence of fluorine ions. The anodization process on ground or polished samples was performed at experimental condition of 30 V for 1 h. The selected anodized samples were heat treated for 2 h at 500 °C under flowing argon. All samples were characterized by scanning electron microscopy, X-ray diffraction analysis, and Raman spectroscopy. The corrosion rate in physiological solution reached 0.0043, 0.0182, and 0.0998 mm per year for the samples in polished and not-anodized, as-anodized, and anodized-heat treated conditions, respectively.

Field of study: Materials science
Finite Larmor radius approximation for collisional magnetic confinement. Part II: the Fokker-Planck-Landau equation

This paper is devoted to the finite Larmor radius approximation of the Fokker-Planck-Landau equation, which plays a major role in plasma physics. We obtain a completely explicit form for the gyroaverage of the Fokker-Planck-Landau kernel, accounting for diffusion and convolution with respect to both velocity and (perpendicular) position coordinates. We show that the new collision operator enjoys the usual physical properties ; the averaged kernel balances the mass, momentum, kinetic energy and dissipates the entropy, globally in velocity and perpendicular position coordinates.

Field of study: Mathematics
Screening of marine microalgae for bioremediation of cadmium-polluted seawater.

Twenty four strains out of 191 marine microalgal strains exhibited cadmium (Cd) resistance. They were tested for their Cd removal ability in growth media containing 50 microM Cd. Six strains out of 19 green algae and one out of five cyanobacteria removed more than 10% of total Cd from the medium. The marine green alga Chlorella sp. NKG16014 showed the highest removal of Cd 48.7% of total. Cd removal by NKG16014 was further quantitatively evaluated by measuring the amount of cell adsorption and intracellular accumulation. After 12 days incubation, 67% of the removed Cd was accumulated intracellularly and 25% of the Cd removed was adsorbed on the algal cell surface. The maximum Cd adsorption (qmax) was estimated to be 37.0 mg Cd (g dry cells)-1 using the Langmuir sorption model. The Cd removal by freeze-dried NKG16014 cells was also determined. Cd was more quickly adsorbed by dried cells than that by living cells, with a qmax of 91.0 mg Cd (g dry cells)-1.

Field of study: Biology, Engineering
Microskills Practice Versus Mental Practice Training for Competence in Decision-Making Counseling

Students enrolled in an introductory counseling course who lacked training and experience as counselors were randomly assigned to one of two decisionmaking counseling training groups or to a wait-control (WC) group. Microskills practice (MS) and mental practice (MP) were each separately combined with instructions, modeling, feedback, and review in the two treatment groups. All trainees conducted posttraining simulated counseling interviews, and their videotapes provided data for analysis of the quality of their counseling competence and their proficiency with the decision-making counseling paradigm. Multivariate analysis of variance and follow-up analyses of data from independent ratings of the videotapes indicated that MS and MP were superior to WC on three of five qualitative dimensions and a proficiency measure. Implications for teaching higher-order counseling skills are discussed, and further research hypotheses are suggested. The purpose of this study was to compare the effects of microskills practice (MS) and mental practice (MP) on acquisition of decision-making counseling competence. Counseling psychology knows more about teaching lower-order skills such as attending and responding than about teaching higher-order skills such as decisionmaking and test-interpretation counseling (Kasdorf & Gustafson, 1978). Research in this area is important so that we may learn whether practice methods that work with lower-order skills are also effective in teaching higher-order skills (Fuqua & Gade, 1982) and so that we can assess the cost effectiveness of comparative methods, especially where training group size increases and length of training time decreases. Earlier research validates the effect of microskills practice on acquisition of lower-order skills (cf. Kasdorf & Gustafson, 1978). In addition, Baker, Scofield, Munson, and Clayton (1983) found mental practice equal to microskills practice on a qualitative counseling measure and superior in teaching basic responding skills after a brief (150 min) training program. One effort to teach decision-making counseling skills led to the conclusion that a comprehensive format of lecture, instructions, modeling, practice, and feedback was superior to subsets of the same components (Wallace, Horan, Baker, & Hudson, 1975). Knowledge about the importance of in

Field of study: Psychology
EFEITOS DE UM PROGRAMA DE EDUCAÇÃO PELO ESPORTE NO DOMÍNIO DAS HABILIDADES MOTORAS FUNDAMENTAIS E ESPECIALIZADAS: ÊNFASE NA DANÇA - DOI: 10.4025/reveducfis.v19i4.5254

The aim of this study was to analyze the effects of a program education through sport in fundamental motor skills and specialized of the dance in children. At the intervention program developed in 10 weeks, the TARGET structure assumptions to the learning have been implemented. The assessment was driving in pre and post intervention and in context of learning, using the Test of Gross Motor Development-2. The results indicated that the Motor Intervention Program fosters motor gains in fundamental motor skills and specialized, reinforcing the effective participation of children in the practice of dance.

Field of study: Education
Consequences of anthropogenic disturbances on soil seed bank diversity and nurse shrub effect in a semiarid rangeland

What is the effect of common land use histories on the diversity, richness, spatial distribution and abundance of the soil seed bank (SSB)? Does the effect change between different microsites under shrub canopy? To address these questions we selected seven sites with different grazing and fire histories in the Patagonian Monte desert. We took soil samples in seven microsites at different distances of the trunk along a windward/leeward transect through shrub patches to estimate the SSB of perennial grasses, shrubs and annuals. Shrubs SSB was scarce. The nurse shrub effect on perennial grass SSB was evident at sites with a low disturbance intensity (as sites without continuous grazing), and higher on the leeward side under the shrub canopy. High disturbance intensity (such as permanent grazing) promoted a decrease in perennial grass SSB and an increase in annuals SBB (especially non-native). Land use histories related to fire showed a moderated disturbance response (medium values for both groups). Differences between land use histories varied depending on the windward/leeward microsite from which the SSB was analysed. Our results suggest a nurse effect of the shrub patches on the spatial distribution and abundance of the SSB, but this effect decrease under continuous grazing. Fire seems to have a positive effect on perennial grass SSB. Nevertheless, fire characteristics must be controlled. Moreover, perennial grass SSB was almost depleted under continuous grazing, driving the grazed system towards a vulnerable state; and annual non-native species take advantage of this disturbance and dominate the SSB.

Field of study: Environmental science
lao nian bing de te dian yu yu fang yan jiu

老年病特点患有慢性疾病，合并症较多，多伴有多脏器功能衰竭、多系统功能障碍、多种老年问题与老年综合征，用药量、种类较大，副作用反应多且重，危险因素较多，治疗、护理难度较大。每个人应提高关注自身健康，养成良好的生活习惯、生活方式、社会行为，规避致病因素，树立疾病风险意识，积极诊疗，促进病患转归。

Field of study: Medicine
Biodegradation of phthalate esters in polluted soil by using organic amendment

This study investigated the biodegradation of the phthalate esters (PAEs) di-n-butyl phthalate (DBP) and di-(2-ethyl hexyl) phthalate (DEHP) in sludge and sludge-amended soil. DBP (100 mg kg−1) and DEHP (100 mg kg−1) were added to sewage sludge, which was subsequently added to soil. The results showed that sewage sludge can degrade PAEs and the addition of sewage sludge to soil enhanced PAE degradation. Sludge samples were separated into fractions with various particle size ranges, which spanned 0.1–0.45 μm to 500–2000 μm. The sludge fractions with smaller particle sizes demonstrated higher PAE degradation rates. However, when the different sludge fractions were added to soil, particle size had no significant effect on the rate of PAE degradation. The results from this study showed that microbial strains F4 (Rhodococcus sp.) and F8 (Microbacterium sp.) were constantly dominant in the mixtures of soil and sludge.

Field of study: Agricultural and Food sciences