nils-herrmann/clean_scirepeval huggingface dataset:
Expression of intracellular adhesion molecule-1 linking superoxide to mobilization of granulocytes and macrophages after periarterial blood in rat femoral artery: effect of rebamipide.

To clarify the mechanism(s) involved in the perivascular mobilization of granulocytes and macrophages by periarterial autologous blood (PAAB) in the vicinity of the femoral artery (FA) in rats, superoxide production as well as expression of intercellular adhesion molecule-1 (ICAM-1) were determined by conducting both in vitro and in vivo experiments.



In an in vitro study, a significant amount of superoxide inhibited by diphenyleneiodonium (20 microM and 100 microM) was identified at 3 hours after application of 10% whole blood to the aortic segments, and these results were correlated with in vitro ICAM-1 expression. High expression of ICAM-1 was subsequently demonstrated in these segments at 24 hours in in vitro and in vivo studies. In the in vivo study, an increased mobilization of granulocytes paralleled with a high expression of ICAM-1 in the vessels at 24 hours after administration of PAAB to the FA and then declined. Subsequently, macrophage infiltration progressively increased at all layers throughout a period of 7 to 12 days. Pretreatment with rebamipide (100 and 300 mg kg(-1) day(-1), orally) significantly inhibited the expression of ICAM-1 with inhibition of mobilization of granulocyte/macrophage.



These findings suggest that application of PAAB to the rat FA causes superoxide-linked expression of ICAM-1 and mobilization of granulocyte and macrophages. Thus, the potential value in suppressing these variables stimulated by PAAB is indicated in therapeutic strategies for prevention and possible regression of vasospasm after subarachnoid hemorrhage.

Field of study: Medicine
Direct measurement of the magnetic penetration depth by magnetic force microscopy

We present an experimental approach using magnetic force microscopy for measurements of the absolute value of the magnetic penetration depth $\lambda$ in superconductors. $\lambda$ is obtained in a simple and robust way without introducing any tip modeling procedure via direct comparison of the Meissner response curves for a material of interest to those measured on a reference sample. Using a well-characterized Nb film as a reference, we determine the absolute value of $\lambda$ in a Ba(Fe$_{0.92}$Co$_{0.08}$)$_{2}$As$_{2}$ single crystal and a MgB$_2$ thin film through a comparative experiment. Our apparatus features simultaneous loading of multiple samples, and allows straightforward measurement of the absolute value of $\lambda$ in superconducting thin film or single crystal samples.

Field of study: Physics
File-injection Attack and Forward Security for Order-revealing Encryption

Order-preserving encryption (OPE) and order-revealing encryption (ORE) are among the core ingredients for encrypted database (EDB) systems as secure cloud storage. In this work, we study the leakage of OPE and ORE and their forward security. We propose generic yet powerful file-injection attacks (FIAs) on OPE/ORE, aimed at the situations of possessing order by and range queries. The FIA schemes only exploit the ideal leakage of OPE/ORE (in particular, no need of data denseness or frequency). We also improve its efficiency with the frequency statistics using a hierarchical idea such that the high-frequency values will be recovered more quickly. Compared with other attacks against OPE/ORE proposed in recent years, our FIA attacks rely upon less demanding conditions and are more effective for attacking the systems with the function of data sharing or transferring like encrypted email system. We executed some experiments on real datasets to test the performance, and the results show that our FIA attacks can cause an extreme hazard on most of the existing OPE and ORE schemes with high efficiency and 100% recovery rate. In order to resist the perniciousness of FIA, we propose a practical compilation framework for achieving forward secure ORE. The compilation framework only uses some simple cryptographical tools like pseudo-random function, hash function and trapdoor permutation. It can transform most of the existing OPE/ORE schemes into forward secure ORE schemes, with the goal of minimizing the extra burden incurred on computation and storage. We also present its security proof and execute some experiments to analyze its performance.

Field of study: Computer science, Mathematics
Diversity of aquatic prokaryotic communities in the Cuatro Cienegas basin.

The Cuatro Cienegas basin (Coahuila, México) is a composite of different water systems in the middle of the desert with unusually high levels of endemism and diversity in different taxa. Although the diversity of macrobiota has been well described, little is known about the diversity and distribution of microorganisms in the oligotrophic ponds. Here we describe the extent and distribution of diversity found in aquatic prokaryotic communities by analysis of terminal restriction fragment length polymorphisms (T-RFLP) of 16S rRNA genes and phylogenetic analysis of cloned genes. Twelve locations within the basin were sampled. Among all the samples, we found a total of 117 operational taxonomic units (OTUs) using T-RFLPs, which ranged in any single sample from four to 49. OTU richness and Shannon diversity indices for different sites varied, but none were particularly high. 16S rRNA gene sequence data showed 68 different phylotypes among 198 clones. The most abundant phylotypes were Gamma- and Betaproteobacteria, and extreme halophiles. The differences among sites were significant; 45 TRFs were found only once, and 37% of the total diversity was represented by differences between sites, suggesting high beta-diversity. Further studies are needed to test whether this is a direct consequence of environmental heterogeneity in the basin.

Field of study: Biology, Environmental science
Folk healers: a different perspective.

Non-western folk healers and their methods are often dismissed by westerners who feel that only physicians who have been well schooled in the Hippocratic tradition at an established university can provide health care adequately. The author, however, asserts that folk healers have a valuable role in medicine. A large percentage of the world's population relies on these practitioners as primary health care providers, and thus their contribution to medicine is considerable on a global scale. Similarly, treatments and pharmaceutical agents discovered by tribal healers have, on occasion, been keenly adopted by the west. Acknowledging the significance of this contribution can stimulate further study of alternative treatment options and philosophies.

Field of study: Medicine
Derivatives of heterocyclic α-iminocarboxylic acids. 4. Reduction of N-alkoxycarbonyl derivatives of α-iminocarboxylic acids

When N-methoxycarbonyl and N-benzoxycarbonyl derivatives of methyl esters of aziridine-2-carboxylic acid, L-proline, L-thioproline, and pipecolic acid interact with NaBH4 in tert-butanol/methanol, the products of reduction of the C-methoxycarbonyl group of the original compounds are accompanied by bicyclic urethanes and oxazolidines. Reduction of N-maleates and N-fumarates of heterocyclic α-iminocarboxylic acids leads to the formation of α-hydroxymethyl-N-[4-(2-oxo-2,5-dihydrofuryl)] derivatives of pyrrolidine, piperidine, 1,3-thiazolidine, and 1,4-thiazan. In the latter case, 1-aza-2-hydroxymethyl-4-oxo-5-oxa-9-thiabicyclo [5.4.0]undecene-2 is also obtained. The N-maleates and fumarates of aziridine-2-carboxylic acid are reduced anomalously by sodium borohydride, forming 2-hydroxymethyl-2-(β-hydroxyethyl)-3-oxa-1-azabicyclo[3.1.0]hexanes.

Field of study: Chemistry
Adsorption of CO₂, CH₄, and N₂ on ordered mesoporous carbon: approach for greenhouse gases capture and biogas upgrading.

Separation of CO₂ and N₂ from CH₄ is significantly important in natural gas upgrading, and capture/removal of CO₂, CH₄ from air (N₂) is essential to greenhouse gas emission control. Adsorption equilibrium and kinetics of CO₂, CH₄, and N₂ on an ordered mesoporous carbon (OMC) sample were systematically investigated to evaluate its capability in the above two applications. The OMC was synthesized and characterized with TEM, TGA, small-angle XRD, and nitrogen adsorption/desorption measurements. Pure component adsorption isotherms of CO₂, CH₄, and N₂ were measured at 278, 298, and 318 K and pressures up to 100 kPa, and correlated with the Langmuir model. These data were used to estimate the separation selectivities for CO₂/CH₄, CH₄/N₂, and CO₂/N₂ binary mixtures at different compositions and pressures according to the ideal adsorbed solution theory (IAST) model. At 278 K and 100 kPa, the predicted selectivities for equimolar CO₂/CH₄, CH4/N₂, and CO₂/N₂ are 3.4, 3.7, and 12.8, respectively; and the adsorption capacities for CH₄ and CO₂ are 1.3 and 3.0 mmol/g, respectively. This is the first report of a versatile mesoporous material that displays both high selectivities and large adsorption capacities for separating CO₂/CH₄, CH₄/N₂, and CO₂/N₂ mixtures.

Field of study: Environmental science
A modified gradient based algorithm for solving Sylvester equations

In this paper a modified gradient based algorithm for solving Sylvester equations is presented. Different from the gradient based method introduced by Ding and Chen [7] and the relaxed gradient based algorithm proposed by Niu et al.  , the information generated in the first half-iterative step is fully exploited and used to construct the approximate solution. Theoretical analysis shows that the new method converges under certain assumptions. Numerical results are given to verify the efficiency of the new method.

Field of study: Mathematics
Aviation Safety Concerns for the Future

The Future Aviation Safety Team (FAST) is a multidisciplinary international group of aviation professionals that was established to identify possible future aviation safety hazards as undesirable consequences of changes. Since 2004, the FAST and its former members have been maintaining a catalogue of ‘Areas of Change’ (AoC) that could potentially influence aviation safety. The horizon for such changes is between 5 to 20 years. In this context, changes must be understood as broadly as possible. An AoC is a description of the change, not an identification of the hazards that result from the change. An analysis of the AoCs identified in 2004 demonstrates that changes catalogued many years ago, were directly evident in the majority of fatal aviation accidents over the past ten years. This ex-post-facto analysis of the AoCs identified in 2004 demonstrates that changes catalogued previously can provide an opportunity for predicting casual factors of future safety incidents. This paper presents an overview of the current AoC catalogue and a subsequent discussion of related aviation safety concerns. Interactions among these future changes may weaken critical functions that must be maintained to ensure safe operations. Safety assessments that do not appreciate or reflect the consequences of complexity due to such interactions will not be fully informative and can lead to inappropriate trade-offs and increases of other risks. The use of an “Areas of Change” concept permits a systematic analysis of ongoing and future phenomena that may interact with a technology or operational concept under study and generate unanticipated hazards.

Field of study: Computer science, Engineering
Collagen-to-collagen prey-predator isotopic enrichment (Δ13C, Δ15N) in terrestrial mammals - a case study of a subfossil red fox den

Trophic Enrichment Factor (TEF) is the main parameter used in isotopic trophic ecology. TEF values can be derived from specimens subjected to experimental feeding or from free-ranging specimens whose dietary behavior is well monitored, and it can be measured for different tissues of animal body. Direct collagen-to-collagen TEF is a key parameter for fossil material and needs to be well constrained in order to ascertain the reliability of the palaeodietary models. In this paper, we present isotopic results for a subfossil bone accumulation related to red fox (Vulpes vulpes) activity, discovered in an abandoned mine in Potok-Senderki (Poland). The objective was to report δ13C and δ15N collagen data for red foxes and their prey. These data were used to calculate a prey-predator collagen-to-collagen TEF and provided important information for interpreting stable isotope fractionation in terrestrial food webs. We used different taphonomic indexes to calculate the fox mean diet. The presence of juvenile and adult individuals of fox allowed us to specify the difference in isotopic enrichment according to the age class of the predator. Δ13C and Δ15N values calculated here for fox were similar to TEF values presented previously for wolf and lynx, but characterized by wider standard deviation.

Field of study: Environmental science, Geography
A study on Speaker Identification Using Spectral Ratio between Air-Transmitted Speech Sounds and Bone-Transmitted Speech Sounds

A bone-conductive microphone which transforms bone-transmitted speech sounds through skull into electronic signals has two advantages. One is to operate in hands free mode, and another is to be anti-noise. Therefore, it is expected to match the man-machine interface for wearable computers. Here, we examined and analyzed the possibility of a speaker identification system with the MFCC of air and bone-transmitted speech sounds to 5 Japanese vowels. This paper shows that the system using spectral ratio between air-transmitted speech sounds and bone-transmitted speech sounds gives better performance than the system using air-transmitted speech sounds.

Field of study: Computer science
The migration of gymnastics coaches from the Former Soviet Union to New Zealand: an actor–network theory perspective

This article uses actor–network theory (ANT) to examine factors that influenced highly skilled gymnastics coaches from the gymnastics stronghold of the Former Soviet Union to migrate to the geographically and culturally distant nation of New Zealand. Our research diverges from the emphasis on the professional sports labour market that has dominated sports migration research and extends upon the network-orientated approaches that have recently been utilised in sport. The article is informed by the stories of 10 migrant gymnastics coaches obtained through qualitative interviews. We demonstrate how the ANT approach helps reveal how multiple micro- and macro-factors assembled together to motivate and facilitate the coaches’ migration. While economic factors can be identified, we draw attention to a unique facet that has received little previous attention in the sports migration literature: the non-human. We show how the coaches’ migration was facilitated by non-humans such as a disease, Skype, leotards and work visas and that these non-humans played a role in enabling or disrupting migration.

Field of study: Sociology
Sensitivity of the mouse to changes in azimuthal sound location: angular separation, spectral composition, and sound level.

Auditory spatial acuity was measured in mice using prepulse inhibition (PPI) of the acoustic startle reflex as the indicator response for stimulus detection. The prepulse was a "speaker swap" (SSwap), shifting a noise between two speakers located along the azimuth. Their angular separation, and the spectral composition and sound level of the noise were varied, as was the interstimulus interval (ISI) between SSwap and acoustic startle reflex elicitation. In Experiment 1 a 180 degrees SSwap of wide band noise (WBN) was compared with WBN Onset and Offset. SSwap and WBN Onset had near equal effects, but less than Offset. In Experiment 2 WBN SSwap was measured with speaker separations of 15, 22.5, 45, and 90 degrees . Asymptotic level and the growth rate of PPI increased with increased separation from 15 to 90 degrees , but even the 15 degrees SSwap provided significant PPI for the mean performance of the group. SSwap in Experiment 3 used octave band noise (2-4, 4-8, 8-16, or 16-32 kHz) and separations of 7.5 to 180 degrees . SSwap was most effective for the highest frequencies, with no significant PPI for SSwap below 8-16 kHz, or for separations of 7.5 degrees . In Experiment 4 SSwap had WBN sound levels from 40 to 78 dB SPL, and separations of 22.5, 45, 90, and 180 degrees : PPI increased with level, this effect varying with ISI and angular separation. These experiments extend the prior findings on sound localization in mice, and the dependence of PPI on ISI adds a reaction time-like dimension to this behavioral analysis.

Field of study: Biology, Psychology
ENOS-G894T polymorphism is a risk factor for essential hypertension in China.

Vascular endothelial cells produce nitric oxide (NO), which contributes to the regulation of blood pressure and regional blood flow. Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are associated with coronary artery disease; however, associations between polymorphism (G894T) of the eNOS gene and essential hypertension remain unclear. This study was designed to investigate the association between a eNOS-G894T polymorphism and essential hypertension (EH). A total of 190 Chinese EH patients (EH group) and 94 healthy participants (control group) were included in the study. eNOS-G894T was determined using multi-polymerase chain reaction and polymorphisms in eNOS-G894T were genotyped using gene chip technology. Patients carrying eNOS GT + TT genotypes had a higher risk of EH than those carrying the GG genotype (OR = 2.82, 95% CI: 1.05-7.60, P = 0.033). The EH group showed a significantly higher frequency of the T-allele compared with controls (OR = 3.48, 95% CI: 1.34-9.07; P = 0.007). T was found to be significantly associated with EH in the dominant genetic model. Thus, the study demonstrated a significant and independent association between a eNOS-G894T polymorphism and EH in the Chinese patients. The study also showed that eNOS-G894T polymorphism is a risk factor for EH in Chinese patients.

Field of study: Biology, Chemistry, Physics
Resistance to change and preference for variable versus fixed response sequences.

In Experiment 1, 4 pigeons were trained on a multiple chain schedule in which the initial link was a variable-interval (VI) 20-s schedule signalled by a red or green center key, and terminal links required four responses made to the left (L) and/or right (R) keys. In the REPEAT component, signalled by red keylights, only LRLR terminal-link response sequences were reinforced, while in the VARY component, signalled by green keylights, terminal-link response sequences were reinforced if they satisfied a variability criterion. The reinforcer rate for both components was equated by adjusting the reinforcer probability for correct REPEAT sequences across sessions. Results showed that initial- and terminal-link responding in the VARY component was generally more resistant to prefeeding, extinction, and response-independent food than responding in the REPEAT component. In Experiment 2, the REPEAT and VARY contingencies were arranged as terminal links of a concurrent chain and the relative reinforcer rate was manipulated across conditions. For all pigeons, initial-link response allocation was biased toward the alternative associated with the VARY terminal link. These results replicate previous reports that operant variation is more resistant to change than operant repetition (Doughty & Lattal, 2001), and show that variation is preferred to repetition with reinforcer-related variables controlled. Behavioral momentum theory (Nevin & Grace, 2000) predicts the covariation of preference and resistance to change in Experiments 1 and 2, but does not explain why these aspects of behavior should depend on contingencies that require repetition or variation.

Field of study: Biology, Psychology
Heavy metal content of produce grown in San Juan County (New Mexico, USA)

however, on August 5, 2015, three million gallons flowed into the agricultural region of Farmington, New Mexico and the Navajo Nation. Consumers and growers in the region were fearful that produce might absorb heavy metals from contaminated irrigation water originating from these rivers. Samples were collected from the region including corn (n = 30), pumpkin (n = 10), squash (n = 10), and cucumber (n = 10) then processed and tested using inductively coupled plasma-optical emission spectrometry (ICP-OES) for concentrations of nine metals of interest. These include toxic metals: Al, As, and Pb, which were compared to the World Health Organization limits, 18.29 mg d−1, 0.192 mg d−1, and 0.05 mg kg−1, respectively and essential metals: Cr, Fe, Mn, Zn, Ca, and Cu whose levels were compared to the National Academies’ dietary references for tolerable upper intake levels. Results indicate that produce grown in the region contained significantly less metal than the allowable limits, except for Pb in two corn samples. This research is the first attempt to monitor and analyze heavy metal absorption of produce in the area.

Field of study: Agricultural and Food sciences
Evaluating the Effects of KCl on Thermal Behavior and Reaction Kinetics of Medium Density Fiberboard Pyrolysis

The effects of potassium chloride (KCl) on the pyrolysis of medium density fiberboard (MDF) were investigated by using thermogravimetry/Fourier-transfer infrared spectroscopy (TG-FTIR). Five MDF samples treated with different KCl concentrations (0%, 0.5%, 1%, 2% and 3%) were heated with a heating rate of 20 °C/min. The thermogravimetry (TG) results showed that KCl caused the primary pyrolysis stage towards lower temperatures. The FTIR results indicated that with the concentrations of KCl, the formation of CH4 and C=O functional groups decreased while the formation of CO2 and CO increased. To figure out the reason for the observed phenomena, the kinetic parameters in primary pyrolysis and the secondary charring reaction were estimated by a differential evolution (DE) optimization algorithm. The prediction indicated that KCl shifted the initial degradation temperature of each component of MDF towards a lower temperature. Char and gas yields increased with the concentration of KCl, whereas the tar yield reduced. The changes in activation energies revealed that KCl played a catalyst role in the reaction of resin, hemicellulose and cellulose in primary pyrolysis. For lignin, KCl had little effect. In the secondary charring reaction, KCl apparently promoted the reaction of tar. The catalytic effect of KCl on MDF pyrolysis was the combination of primary pyrolysis and the secondary charring reaction. Finally, the optimal catalytic concentration for KCl on MDF pyrolysis was analyzed.

Field of study: Materials science
An interpolation theorem between one-sided Hardy spaces

In this paper we generalize an interpolation result due to J.-O. Strömberg and A. Torchinsky to the case of one-sided Hardy spaces. This generalization is important in the study of the weak type (1,1) for lateral strongly singular operators. We shall need an atomic decomposition in which for every atom there exists another atom supported contiguously at its right. In order to obtain this decomposition we have developed a rather simple technique to break up an atom into a sum of others atoms.

Field of study: Mathematics
Synthese und Eigenschaften silylierter 1,3,4‐Oxadiazolin‐2‐one

5-Substituierte 3-Trimethylsilyl-1,3,4-oxadiazolin-2-one 6 sind durch Silylierung der entsprechenden 1,3,4-Oxadiazolin-2-one 5 oder durch Silylierung der 3-Acyclcarbazinsaure-phenylester 1 leicht zuganglich. Sie isomerisieren sich nicht zu den 2-Trimethylsiloxy-1,3,4-oxadiazolen 7 und sind thermisch so stabil, das selbst bei Temperaturen von 200–300°C eine Destillation unter Normaldruck moglich ist. 
 
 
 
Synthesis and Properties of Silylated 1,3,4-Oxadiazolin-2-ones 
 
 
 
5-Substituted 3-trimethylsilyl-1,3,4-oxadiazolin-2-ones 6 are readily accessible by silylation of the corresponding 1,3,4-oxadiazolin-2-ones 5 or by silylation of phenyl 3-acylcarbazates 1. They do not rearrange to the isomeric 2-trimethylsiloxy-1,3,4-oxadiazoles 7 and their thermal stability permits distillation at 200–300°C under normal pressure.

Field of study: Chemistry