nils-herrmann/clean_scirepeval huggingface dataset:
A Safety and Comfort Lane Change for Sportive Highly Automated Driving Truck

The major goal of this master thesis is to improve truck safety and comfort during lane change manoeuvres. This thesis focuses on the scenario of the driver doing sports exercises inside the cabin when the vehicle is driving automatically on a highway. This topic is one of the foci of the international GlobalDrive project from Technical University of Munich, which aims at sports exercises inside highly automated driving truck cabin by 2030. Using a special chair, drivers are able to do different types of exercises in the cabin. However, the acceleration, deceleration and jerk of normal highly automated vehicles can hardly satisfy the safety and comfort requirements for sports exercises, especially during lane changes. It is very difficult for the driver to keep balance when the lateral or longitudinal jerk and acceleration reach a certain level. In order to provide a suitable environment for exercises, a multi level control architecture has been designed to satisfy the safety and comfort requirements from an ergonomics aspect. The proposed control scheme will make it easier for the driver to keep balance. Prevention of rollover is included in the architecture, while a Cruise Control (CC) Adaptive Cruise Control (ACC) Cooperative Adaptive Cruise Control (CACC) strategy is responsible for the longitudinal safety of the truck. Simulations in realistic and safety critical scenarios show the effectiveness of the approach.
Making the Emperor's New Clothes Visible in Anti Racist Teacher Education: Enacting a Pedagogy of Discomfort with White Preservice Teachers

The failures of university based teacher education programs in the United States with regard to the preparation of White preservice teachers for engagement with students who embody marginalized racial identities in public schools are well documented. One such shortcoming is the inadequate attention paid to the unholy trinity of race, racism, and White supremacy. This article details how I, a Black teacher educator, performed a self study on my utilization of a pedagogy of discomfort (Boler, 1999) in a course housed in a social justice oriented program that enrolled primarily White preservice teachers. Using critical theories on race and affect in my analysis of a racialized, affectively charged classroom incident, I find that enacting discomfort as pedagogy provoked both the preservice teachers and me to individually and collectively make meaning of the contours of racial oppression by noticing and listening to the interactions between our bodies and emotions. Additionally, employing a pedagogy of discomfort cultivated White preservice teachers' emotional openness to supporting each other in a learning community premised on political relationships as vessels for deepening critical consciousness (Freire, 1968/2000) specific to race, racism, and White supremacy. These findings illuminate the radical affordances of discomfort vis a vis pedagogical subversion in learning spaces, particularly those designed to trouble the tight yet seemingly invisible hold that White supremacy maintains on teacher education.
WAZIRI CULTURE AND PASHTUN TRIBAL GOVERNANCE SYSTEM A MISSING LINK TO HALT THE DEADLIEST WAR IN WILD WAZIRISTAN

Waziristan, the most southern tribal agency on Pakistan's western frontier, has a long history of independence and defeating the invaders; those who aimed to bring the area under their central authoritative control likewise administrative jurisdiction and Wazir tribes to breath beneath the forced psychosomatic supremacy, induced with full power. However, the consistent upshots of Wazirs vanquished the attacker's fate. Ultimately, the Wazir tribes were dealt with skilful tactics of presenting due respect to local tribal social customs. It was followed by recognition of their tribal governance system and empowerment of the tribal elders to indirectly administer the wild frontier, which has resulted in victorious regional control for decades and peace prevailed in the region. But, last decade's turmoil has made the area and its inhabitants a sizzling concern in the pursuit of pledging un conditional support and sanctuary to Taliban and other extremists fighters. Hence, neglecting the tribal liberation psyche, diminishing the local governance system and undermining the bygone popular role of the tribal elders, advanced tactics of war were explored by the consecutive Pakistan governments and its allies. However, it resulted in the ever floating situation of Waziristan with extremism both in and out of Waziristan. The current situation still can be transformed to its realistic old nonviolent position; no further blood shed both in and out of Waziristan, only on admiring Waziri liberation psyche and reforming tribal governance system.
Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa Associated Microbiota and Preventing Bacterial Translocation.
Venue: Cell host microbe

Approximately half of all deaths from liver cirrhosis, the tenth leading cause of mortality in the United States, are related to alcohol use. Chronic alcohol consumption is accompanied by intestinal dysbiosis and bacterial overgrowth, yet little is known about the factors that alter the microbial composition or their contribution to liver disease. We previously associated chronic alcohol consumption with lower intestinal levels of the antimicrobial regenerating islet derived (REG) 3 lectins. Here, we demonstrate that intestinal deficiency in REG3B or REG3G increases numbers of mucosa associated bacteria and enhances bacterial translocation to the mesenteric lymph nodes and liver, promoting the progression of ethanol induced fatty liver disease toward steatohepatitis. Overexpression of Reg3g in intestinal epithelial cells restricts bacterial colonization of mucosal surfaces, reduces bacterial translocation, and protects mice from alcohol induced steatohepatitis. Thus, alcohol appears to impair control of the mucosa associated microbiota, and subsequent breach of the mucosal barrier facilitates progression of alcoholic liver disease.
Effects of Reg3 Delta Bioactive Peptide on Blood Glucose Levels and Pancreatic Gene Expression in an Alloxan Induced Mouse Model of Diabetes.
Venue: Canadian journal of diabetes

The endocrine regeneration of the pancreas holds great potential for stable diabetes therapy. The Regeneration (Reg) family of proteins has been associated with pancreas regeneration. Hence, the Reg3 delta bioactive peptide from a mouse was evaluated to see whether it can reverse hyperglycemia in a mouse model of diabetes with any effects on pancreatic gene expression.  In this study, we administrated the synthetic Reg3 delta bioactive peptide to healthy mice and to alloxan induced mouse models of diabetes for 30 days, with weekly measurements of body weight and blood glucose levels. After 1 month, pancreatic gene profiling of these mice was performed for the Ngn 3, Pdx 1, MapK8, IGF 1, IGF2bp2, Reg3 beta and Reg3 delta genes.  The glycemic levels in mice with diabetes were decreased significantly, restored almost to normal. Furthermore, the gene expression levels measured by quantitative polymerase chain reaction (qPCR) showed that messenger RNA (mRNA) levels of 2 important transcription factors (Ngn 3 and Pdx 1) were increased during the Reg3 delta peptide treatment.  This study shows that Reg3 delta has the potential to reverse hyperglycemia by modulating gene expression in pancreatic endocrine precursor markers Pdx 1 and Ngn 3, which require further investigation at the protein and immunohistology levels.
Antitumor Activity of RXDX 105 in Multiple Cancer Types with RET Rearrangements or Mutations
Venue: Clinical Cancer Research

While multikinase inhibitors with RET activity are active in RET rearranged thyroid and lung cancers, objective response rates are relatively low and toxicity can be substantial. The development of novel RET inhibitors with improved potency and/or reduced toxicity is thus an unmet need. RXDX 105 is a small molecule kinase inhibitor that potently inhibits RET. The purpose of the preclinical and clinical studies was to evaluate the potential of RXDX 105 as an effective therapy for cancers driven by RET alterations.  The RET inhibitory activity of RXDX 105 was assessed by biochemical and cellular assays, followed by in vivo tumor growth inhibition studies in cell line and patient derived xenograft models. Antitumor activity in patients was assessed by imaging and Response Evaluation Criteria in Solid Tumors ( Biochemically, RXDX 105 inhibited wild type RET, CCDC6 RET, NCOA4 RET, PRKAR1A RET, and RET M918T with low to subnanomolar activity while sparing VEGFR2/KDR and VEGFR1/FLT. RXDX 105 treatment resulted in dose dependent inhibition of proliferation of CCDC6 RET rearranged and RET C634W mutant cell lines and inhibition of downstream signaling pathways. Significant tumor growth inhibition in CCDC6 RET, NCOA4 RET, and KIF5B RET containing xenografts was observed, with the concomitant inhibition of p ERK, p AKT, and p PLCg. Additionally, a patient with advanced RET rearranged lung cancer had a rapid and sustained response to RXDX 105 in both intracranial and extracranial disease.  These data support the inclusion of patients bearing RET alterations in ongoing and future molecularly enriched clinical trials to explore RXDX 105 efficacy across a variety of tumor types.
Components and characteristics of the dopamine reward utility signal
Venue: The Journal of comparative neurology

Rewards are defined by their behavioral functions in learning (positive reinforcement) approach behavior, economic choices, and emotions. Dopamine neurons respond to rewards with two components, similar to higher order sensory and cognitive neurons. The initial, rapid, unselective dopamine detection component reports all salient environmental events irrespective of their reward association. It is highly sensitive to factors related to reward and thus detects a maximal number of potential rewards. It also senses aversive stimuli but reports their physical impact rather than their aversiveness. The second response component processes reward value accurately and starts early enough to prevent confusion with unrewarded stimuli and objects. It codes reward value as a numeric, quantitative utility prediction error, consistent with formal concepts of economic decision theory. Thus, the dopamine reward signal is fast, highly sensitive and appropriate for driving and updating economic decisions.  2016.
Identify The Need for Developing a New Service Quality Model in TodaysScenario: A Review of Service Quality Models

The service industries are mostly customer driven and their survival in the competitive environment largely depends on quality of the services provided by them. Due to the increasing competition in the service sector, customer service is an important part of the organizational growth. The key lies in improving the service selectively, paying attention to more critical attributes as a part of improved customer satisfaction. A large number of research studies for service quality take place in the context of developing countries. There are various models suggested by many authors in relation to service quality but no model take all attributes of service quality. The main objective of this paper is to critically appraise various service quality models and identify issues for future research based on the critical analysis of literature. This study aims at evaluating the different service quality models given by different authors and identifies the need for developing a new model in today's scenario. This study examines 19 models of service quality. Findings of the study explore new model and direction in service quality improvement for different sectors. Data for this study is collected from secondary sources. The empirical findings not only priorities different parameters of service quality but also provide guidelines to focus on the other parameters on which the marketer need to improve.
Impact of Type 1 Diabetes Technology on Family Members/Significant Others of People With Diabetes
Venue: Journal of diabetes science and technology

The aim was to explore the impact of diabetes related technology to ensure that such devices are used in a way that returns maximum benefit from a medical and psychological perspective.  Spouses and caregivers of people with type 1 diabetes were invited to complete an online questionnaire about their experiences with diabetes technologies used by their family members. Participants were recruited via the Glu online community website. Questions explored impact on daily living, frequency and severity of hypoglycemia, and diabetes related distress.  In all, 100 parents/caregivers and 74 partners participated in this survey. Average (mean) duration of living with a person with type 1 diabetes was 16 years (SD 13) for partners, with duration of diabetes for children being 4.2 3.2 years. Average duration of current therapy was 8.3 7.3 years for adults and 3.4 2.9 years for children. Of the participants, 86% partners and 82% parents/caregivers reported diabetes technology had made it easier for their family members to achieve blood glucose targets. Compared to partners, parents/caregivers reported more negative emotions (P .001) and decreased well being (P .001) related to their family members type 1 diabetes. Diabetes related distress was common, as was sleep disturbance associated with device alarms and fear of hypoglycemia. Reduced frequency and severity of hypoglycemia related to device use was reported by approximately half of participants.  There is little doubt about the medical benefit of diabetes technologies and their uptake is increasing but some downsides were reported. Barriers to uptake of technologies lie beyond the mechanics of diabetes management. Supporting users in using diabetes technology to achieve the best possible glycemic control, in the context of their own life, is crucial. Furthermore, understanding these issues with input from the type 1 diabetes community including family members and caregivers will help innovation and design of new technology.
Not at the Dinner Table: Parents' and Children's Perspectives on Family Technology Rules
Venue: CSCW

Parents and children both use technology actively and increasingly, but prior work shows that concerns about attention, family time, and family relationships abound. We conducted a survey with 249 parent child pairs distributed across 40 U.S. states to understand the types of technology rules (also known as restrictive mediation) they have established in their family and how effective those rules are perceived to be. Our data robustly show that children (age 10 17) are more likely to follow rules that constrain technology activities (e.g. no Snapchat) than rules that constrain technology use in certain contexts (e.g. no phone at the dinner table) Children find context constraints harder to live up to, parents find them harder to enforce, and parents' most common challenge when trying to enforce such rules is that children can't put it down. This is consistent with the idea that banning certain technologies is currently easier than setting more nuanced boundaries. Parents and children agree that parents should also unplug when spending time with family, while children alone express frustration with the common parent practice of posting about children online. Together, our results suggest several mechanisms by which designers and families can improve parent child relationships around technology use.
Smart grids deployments within EU projects: The role of smart meters
Venue: 2016 Smart Cities Symposium Prague (SCSP)

There is a large number of European Union (EU) projects that deal with Smart Grids research and deployment. Overall, they provide a substantial amount of knowledge that can be mined to gain useful insights for future projects and on going roll outs of Smart Grid related utilities. In the current paper, we focus on Smart Meters and we evaluate different communication related architectural styles within an Advanced Metering infrastructure (AMI) In particular, we derive from the Joint Research Centre (JRC) Smart Grids projects review three different layouts for Smart Meters two way communication: i) mobile Peer to Peer (P2P) ii) data concentrator supported, and iii) gateway supported. After the discussion about the architectural styles, we look at how common such choices are within EU projects deployments. Overall, we found predominance of both gateway data concentrator architectures over P2P mobile communication layouts. The main outcome of the paper is a mapping of the three architectural styles to the deployments within the selected EU projects. Based on the map, we debate about the implications of such deployments within the current and future Smart Grids context.
Understanding and Improving Convolutional Neural Networks via Concatenated Rectified Linear Units
Venue: ICML

Recently, convolutional neural networks (CNNs) have been used as a powerful tool to solve many problems of machine learning and computer vision. In this paper, we aim to provide insight on the property of convolutional neural networks, as well as a generic method to improve the performance of many CNN architectures. Specifically, we first examine existing CNN models and observe an intriguing property that the filters in the lower layers form pairs (i.e. filters with opposite phase) Inspired by our observation, we propose a novel, simple yet effective activation scheme called concatenated ReLU (CRelu) and theoretically analyze its reconstruction property in CNNs. We integrate CRelu into several state of the art CNN architectures and demonstrate improvement in their recognition performance on CIFAR 10/100 and ImageNet datasets with fewer trainable parameters. Our results suggest that better understanding of the properties of CNNs can lead to significant performance improvement with a simple modification.
Self Organized Al2Cu Nanocrystals at the Interface of Aluminum Based Reactive Nanolaminates to Lower Reaction Onset Temperature.
Venue: ACS applied materials interfaces

Nanoenergetic materials are beginning to play an important role in part because they are being considered as energetic components for materials, chemical, and biochemical communities (e.g. microthermal sources, microactuators, in situ welding and soldering, local enhancement of chemical reactions, nanosterilization, and controlled cell apoptosis) and because their fabrication/synthesis raises fundamental challenges that are pushing the engineering and scientific frontiers. One such challenge is the development of processes to control and enhance the reactivity of materials such as energetics of nanolaminates, and the understanding of associated mechanisms. We present here a new method to substantially decrease the reaction onset temperature and in consequence the reactivity of nanolaminates based on the incorporation of a Cu nanolayer at the interfaces of Al/CuO nanolaminates. We further demonstrate that control of its thickness allows accurate tuning of both the thermal transport and energetic properties of the system. Using high resolution transmission electron microscopy, X ray diffraction, and differential scanning calorimetry to analyze the physical, chemical and thermal characteristics of the resulting Al/CuO interfacial Cu nanolaminates, we find that the incorporation of 5 nm Cu at both Al/CuO and CuO/Al interfaces lowers the onset temperature from 550 to 475 degC because of the lower temperature formation of Al Cu intermetallic phases and alloying. Cu intermixing is different in the CuO/Cu/Al and Al/Cu/CuO interfaces and independent of total Cu thickness: Cu readily penetrates into Al grains upon annealing to 300 degC, leading to Al/Cu phase transformations, while Al does not penetrate into Cu. Importantly, th Al2Cu nanocrystals are created below 63% wt Cu/Al, and coexist with the Al solid solution phase. These well defined th Al2Cu nanocrystals seem to act as embedded Al+CuO energetic reaction triggers that lower the onset temperature. We show that ~10 nm thick Cu at Al/CuO interfaces constitutes the optimum amount to increase both reactivity and overall heat of reaction by a factor of ~20% Above this amount, there is a rapid decrease of the heat of reaction.
Survey on Cardiac Arrhythmia Techniques in ECG Signal

Electrocardiogram (ECG) signal is a graphical representation of the cardiac muscle activity, which is most important biomedical signal. Cardiac Arrhythmia is the abnormality in the Heart which can be diagnosed with the help of Electrocardiogram (ECG) signal. The features of ECG signal can be extracted using various techniques are present in the literature. The peak detection of the QRS Complex and test its suitability for medical diagnosis using MIT BIH database is present in the literature, and the results are compared with the existing models by taking mean absolute relative error and Error% as performance criteria.Finally identified that there is scope of research in Cardiac Arrhythmiaand Computational Intelligence techniques are giving the better results.  Electrocardiogram, Feature Extraction, QRS detection, peak detection, classification and Computational Intelligence.
Essential oil composition in natural populations of Pistacia lentiscus L. from Tunisia: Effect of ecological factors and incidence on antioxidant and antiacetylcholinesterase activities

Essential oil leaves of 14 Tunisian Pistacia lentiscus L. (Anacardiaceae) populations, growing wild in three bioclimatic zones, were analyzed by GC FID and GCMS. The species was found to be rich in monoterpene hydrocarbons (41.9% and sesquiterpene hydrocarbons (40% a pinene (9.9% limonene (8.5% terpinen 4 ol (5.1% b caryophyllene (8.2% germacrene D (11.9% and d cadinene (8.5% were found to be the main compounds. Significant variations of essential oil composition, mainly of major compound percentages (a pinene, limonene, terpinen 4 ol, b caryophyllene, germacrene D and d cadinene) were detected between populations. PCA and CCA analyses showed a substantial chemical differentiation among populations that was mainly attributed to variation of climatic factors (precipitation, Embergers coefficient, summer precipitation, temperature of the warmest months in the year, evapotranspiration and winter cold stress) and altitude between the analyzed populations. P. lentiscus essential oils were found to possess antioxidant and antiacetylcholinesterase activities. These activities varied significantly among populations. Essential oil of the species collected from the population 1 possessed the highest antiradical (993.4 mg TE/g EO) and reducing power (13.8 mmol Fe 2+ /g EO) activities. Essential oil from population 14 exhibited the uppermost capacity to prevent b carotene bleaching (IC 50 557.3 mg/ml) The population 13 showed the most important ferrous ion chelating activity (IC 50 130.6 mg/ml) Essential oil from the population 6 was found to be the most effective inhibitory against acetylcholinesterase. Levels of antioxidant and antiacetylcholinesterase activities varied according to chemical composition of the investigated essential oils.