nils-herrmann/clean_scirepeval huggingface dataset:
Generation of a reassortant avian influenza virus H5N2 vaccine strain capable of protecting chickens against infection with Egyptian H5N1 and H9N2 viruses.
Venue: Vaccine

Avian influenza H5N1 viruses have been enzootic in Egyptian poultry since 2006. Avian influenza H9N2 viruses which have been circulating in Egyptian poultry since 2011 showed high replication rates in embryonated chicken eggs and mammalian cells.  To investigate which gene segment was responsible for increasing replication, we constructed reassortant influenza viruses using the low pathogenic H1N1 PR8 virus as backbone and included individual genes from A/chicken/Egypt/S4456B/2011(H9N2) virus. Then, we invested this finding to improve a PR8 derived H5N1 influenza vaccine strain by incorporation of the NA segment of H9N2 virus instead of the NA of H5N1. The growth properties of this virus and several other forms of reassortant H5 viruses were compared. Finally, we tested the efficacy of this reassortant vaccine strain in chickens.  We observed an increase in replication for a reassortant virus expressing the neuraminidase gene (N2) of H9N2 virus relative to that of either parental viruses or reassortant PR8 viruses expressing other genes. Then, we generated an H5N2 vaccine strain based on the H5 from an Egyptian H5N1 virus and the N2 from an Egyptian H9N2 virus on a PR8 backbone. This strain had better replication rates than an H5N2 reassortant strain on an H9N2 backbone and an H5N1 reassortant on a PR8 backbone. This virus was then used to develop a killed, oil emulsion vaccine and tested for efficacy against H5N1 and H9N2 viruses in chickens. Results showed that this vaccine was immunogenic and reduced mortality and shedding.  Our findings suggest that an inactivated PR8 derived H5N2 influenza vaccine is efficacious in poultry against H5N1 and H9N2 viruses and the vaccine seed replicates at a high rate thus improving vaccine production.
Use of Vaccinia Virus Smallpox Vaccine in Laboratory and Health Care Personnel at Risk for Occupational Exposure to Orthopoxviruses Recommendations of the Advisory Committee on Immunization Practices (ACIP) 2015.
Venue: MMWR. Morbidity and mortality weekly report

On June 25, 2015, the Advisory Committee on Immunization Practices (ACIP) recommended routine vaccination with live smallpox (vaccinia) vaccine (ACAM2000) for laboratory personnel who directly handle 1) cultures or 2) animals contaminated or infected with replication competent vaccinia virus, recombinant vaccinia viruses derived from replication competent vaccinia strains (i.e. those that are capable of causing clinical infection and producing infectious virus in humans) or other orthopoxviruses that infect humans (e.g. monkeypox, cowpox, and variola) (recommendation category: A, evidence type 2 [Box] Health care personnel (e.g. physicians and nurses) who currently treat or anticipate treating patients with vaccinia virus infections and whose contact with replication competent vaccinia viruses is limited to contaminated materials (e.g. dressings) and persons administering ACAM2000 smallpox vaccine who adhere to appropriate infection prevention measures can be offered vaccination with ACAM2000 (recommendation category: B, evidence type 2 [Box] These revised recommendations update the previous ACIP recommendations for nonemergency use of vaccinia virus smallpox vaccine for laboratory and health care personnel at risk for occupational exposure to orthopoxviruses (1) Since 2001, when the previous ACIP recommendations were developed, ACAM2000 has replaced Dryvax as the only smallpox vaccine licensed by the U.S. Food and Drug Administration (FDA) and available for use in the United States (2) These recommendations contain information on ACAM2000 and its use in laboratory and health care personnel at risk for occupational exposure to orthopoxviruses.
Recursion based depletion of human immunodeficiency virus specific naive CD4( T cells may facilitate persistent viral replication and chronic viraemia leading to acquired immunodeficiency syndrome.
Venue: Medical hypotheses

Although antiretroviral therapy has made human immunodeficiency virus (HIV) infection a controllable disease, it is still unclear how viral replication persists in untreated patients and causes CD4( T cell depletion leading to acquired immunodeficiency syndrome (AIDS) in several years. Theorists tried to explain it with the diversity threshold theory in which accumulated mutations in the HIV genome make the virus so diverse that the immune system will no longer be able to recognize all the variants and fail to control the viraemia. Although the theory could apply to a number of cases, macaque AIDS models using simian immunodeficiency virus (SIV) have shown that failed viral control at the set point is not always associated with T cell escape mutations. Moreover, even monkeys without a protective major histocompatibility complex (MHC) allele can contain replication of a super infected SIV following immunization with a live attenuated SIV vaccine, while those animals are not capable of fighting primary SIV infection. Here we propose a recursion based virus specific naive CD4( T cell depletion hypothesis through thinking on what may happen in individuals experiencing primary immunodeficiency virus infection. This could explain the mechanism for impairment of virus specific immune response in the course of HIV infection.
El Riesgo Inherente Al Proveedor Como Criterio Preventivo En La Contratacion Publica (The Inherent Risk of the Supplier as a Preventative Criterion in Public Procurement)

El manejo del riesgo de incumplimiento atribuible a las caracteristicas de los proveedores en la contratacion publica en Colombia se limita a la exigencia de garantias, medidas contractuales de presion o la implementacion de clausulas exorbitantes al derecho comun. En tal sentido, el Estado colombiano carece de una metodologia para monitorear el riesgo que los proveedores acumulan con el tiempo y el riesgo que les es sobreviniente por circunstancias tecnicas, financieras o de mercado; de ahi que no cuente con un registro de informacion parametrizada para clasificar a los contratistas acorde con su historial de desempeno, calidad y proclividad al incumplimiento contractual. Ante lo dicho, el Estado no cuenta con suficientes medidas previas de mitigacion para contrarrestar los efectos nocivos derivados de un reconocido "mal prestador" o de un contratista con potencial de riesgo de incumplimiento medio o alto. Por el contrario, las garantias y exigencias requeridas durante el proceso de seleccion aplican de igual forma para todos los interesados, sin que haya diferenciacion frente a quienes presenten un historial de incumplimientos, multas y/o sanciones, entre otras especificaciones de riesgo. El presente escrito plantea la necesidad de asimilar el concepto de riesgo inherente al proveedor como criterio objetivo y estandarizado, desde una perspectiva preventiva mas que correctiva, de tal suerte que el Estado pueda mejorar la efectividad de sus contratos publicos y disminuir la materializacion de los efectos negativos derivados de la contratacion fallida.
Development of the CCP 200 mathematical model for Syzran CHPP using the Thermolib software package

Simplified cycle diagram of the CCP 200 power generating unit of Syzran CHPP containing two gas turbines PG6111FA with generators, two steam recovery boilers KUP 110/15 8.0/0.7 540/200, and one steam turbine Siemens SST 600 (one cylinder with two variable heat extraction units of 60/75 MW in heatextraction and condensing modes, accordingly) with S GEN5 100 generators was presented. Results of experimental guarantee tests of the CCP 200 steam gas unit are given. Brief description of the Thermolib application for the MatLab Simulink software package is given. Basic equations used in Thermolib for modeling thermo technical processes are given. Mathematical models of gas turbine plant, heat recovery steam generator, steam turbine and integrated plant for power generating unit CCP 200 of Syzran CHPP were developed with the help of MatLab Simulink and Thermolib. The simulation technique at different ambient temperature values was used in order to get characteristics of the developed mathematical model. Graphic comparison of some characteristics of the CCP 200 simulation model (gas temperature behind gas turbine, gas turbine and combined cycle plant capacity, high and low pressure steam consumption and feed water consumption for high and low pressure economizers) with actual characteristics of the steam gas unit received at experimental (field) guarantee tests at different ambient temperature are shown. It is shown that the chosen degrees of complexity, characteristics of the CCP 200 simulation model, developed by Thermolib, adequately correspond to the actual characteristics of the steam gas unit received at experimental (field) guarantee tests; this allows considering the developed mathematical model as adequate and acceptable it for further work.
A Mathematical Model of Gas Turbine Pump Complex

The articles analyzes the state of an extensive network of main oil pipelines of Tyumen region on the basis of statistical data, and also suggest ways of improving the efficiency of energy saving policy on the main transport oil. Various types of main oil pipelines pump drives were examined. It was determined that now there is no strict analytical dependence between main operating properties of the power turbine of gas turbine engine. At the same time it is necessary to determine the operating parameters using a turbine at GTPU, interconnection between power and speed frequency, as well as the feasibility of using a particular mode. Analysis of foreign experience, the state of domestic enterprises supplying the country with gas turbines, features of the further development of transport of hydrocarbon resources allows us to conclude the feasibility of supplying the oil transportation industry of our country with pumping units based on gas turbine drive.
An integrated mathematical model of the human cardiopulmonary system: model development.
Venue: American journal of physiology. Heart and circulatory physiology

Several cardiovascular and pulmonary models have been proposed in the last few decades. However, very few have addressed the interactions between these two systems. Our group has developed an integrated cardiopulmonary model (CP Model) that mathematically describes the interactions between the cardiovascular and respiratory systems, along with their main short term control mechanisms. The model has been compared with human and animal data taken from published literature. Due to the volume of the work, the paper is divided in two parts. The present paper is on model development and normophysiology, whereas the second is on the model's validation on hypoxic and hypercapnic conditions. The CP Model incorporates cardiovascular circulation, respiratory mechanics, tissue and alveolar gas exchange, as well as short term neural control mechanisms acting on both the cardiovascular and the respiratory functions. The model is able to simulate physiological variables typically observed in adult humans under normal and pathological conditions and to explain the underlying mechanisms and dynamics.
Ultrasound Mediated Surface Engineering of Theranostic Magnetic Nanoparticles: An Effective One Pot Functionalization Process UsingMixed Polymers for siRNA Delivery

Nano sized materials have been studied for diverse clinical applications, partly because their size dependent physical properties and nanometer scale dimensions have important roles in biological systems. Synergistic combinations of differently nanostructured materials, such as polymer coated magnetic nanoparticles (NPs) strongly promoted various multifunctional nano medical platforms for simultaneous diagnosis and therapy in the rapidly emerging area of theranostics. In this context, magnetically responsive Ce cation doped maghemite (g Fe2O3) NPs form a useful NPs basis towards a new type of polycationic polymer/organic species grafted maghemite NPs for both drug delivery and imaging. The versatility of the Ce cation doped maghemite NPs fabrication process mediated by high power ultrasound (US) enables the development of a new one step time saving US driven variant fabrication of corresponding polymer/organic species grafted NPs. Thus, two types of organic polycationic species, a branched 25 kDa polyethylene imine (b PEI25) polymer and a generation 2 (G2) PAMAM (poly(amidoamine) dendrimer biopolymer, were simultaneously used during this US mediated NPs system fabrication to effectively deliver optimized small interfering RNA (siRNA) applications as a proof of concept. This unique one step fabrication protocol affords a positively charged magnetic core grafted with mixed organic species nanocomposite particles that enables both gene silencing therapy and magnetic resonance imaging.
Fabrication of a Multimodal Microbubble Platform for Magnetic Resonance, Ultrasound and Fluorescence Imaging Application.
Venue: Journal of nanoscience and nanotechnology

Magnetic resonance (MR) ultrasound (US) and fluorescence imaging are the widely used diagnostic modalities for various experimental and clinical applications. A multimodal poly(lactic acid) microbubble (MB) integrated with the three imaging modalities was fabricated by adsorbing CdTe quantum dots (QDs) onto the surface and encapsulating superparamagnetic iron oxide (SPIO) nanoparticles into the core. The strong fluorescence of the multimodal MBs confirmed that QDs were successfully deposited onto the surface. The in vitro MRI contrasting capability of the multimodal MBs at various concentrations was evaluated by T2 weighted imaging. Furthermore, the in vitro and in vivo ultrasonography indicated that CdTe and SPIO inclusive MBs maintained excellent ultrasound contrast property. These results implied that the nano in micro hybrid materials have the potential as a nanomedical platform for multimodal bioimaging.
Extended event driven observer based output control of networked control systems

This paper investigates the event driven observer based output control of networked control systems. By introducing a tuning parameter and a weighting matrix, an extended event driven threshold is proposed. To obtain the controller and observer gains in a convex manner, a constructive strategy is employed to extract the controller matrix coupled with Lyapunov variables and system matrices. Based on these approaches, a sufficient condition for the closed loop system to be the global uniform ultimate boundedness is ensured in terms of linear matrix inequalities. The validity of the proposed method is illustrated via a numerical example.
Implementation of smart safety helmet for coal mine workers
Venue: 2016 IEEE 1st International Conference on Power Electronics, Intelligent Control and Energy Systems (ICPEICES)

This paper presents implementation of safety helmet for coal mine workers. This helmet is equipped with methane and carbon monoxide gas sensor. This sensor sense the gas and the data is transmitted to the control room wirelessly, through a wireless module called X Bee connected with the helmet. When the methane or carbon monoxide gas concentration is beyond the critical level, controller in the control room triggers an alarm and keeps the plant and the workers safe by preventing an upcoming accident.
Smart Helmet for Coal Miners using Zigbee Technology

This project focuses on a mine supervising system which is based on the cost effective Zigbee system. Our project aims at developing a wireless sensor networks, realized real time surveillance with early warning intelligence on harmful gases, temperature, humidity in mining area and used zigbee communication to reduce potential safety problems in coal production using a Zigbee wireless technology. All these three parameters are detected continuously by temperature sensor, gas sensor, humidity sensor and if they cross the pre defined limit, then the user gets alert as the buzzer will automatically turn on with LED indications. With a zigbee Wireless positioning devices the system might be easily extended. The values of different sensors are continuously transmitted by zigbee transmitter to the remote monitoring unit which are received by zigbee receiver module.
Tuning the Functional Properties of Polysaccharide Protein Bio Based Edible Films by Chemical, Enzymatic, and Physical Cross Linking.
Venue: Comprehensive reviews in food science and food safety

Among natural biopolymers, polysaccharides and proteins are very promising for biodegradable and edible wraps with different characteristics, so that their formulations can be tailor made to suit the needs of a specific commodity. Films prepared from polysaccharides have good gas barrier properties but exhibit lower resistance to moisture compared to protein films (edible) or polylactide films (biodegradable) Protein based films show better mechanical and oxygen barrier properties compared to polysaccharide films. For that reason, film performances may be enhanced by producing blend systems, where hydrocolloids (mixtures of proteins and/or polysaccharides) form a continuous and more cohesive network. However, the lower water barrier properties of hydrocolloid films and their lower mechanical strength in comparison with synthetic polymers limit their applications in food packaging. Therefore, the enhancement of biopolymer film properties has been studied to attain appropriate applications. This review provides an extensive synthesis of the improvement of the properties of edible polysaccharide protein films by way of various chemical, enzymatic, and physical methods. These methods primarily aim at improving the mechanical resistance. They also permit to ameliorate the water and gas barrier properties and related functional properties.
Valoracion forense del riesgo psicologico inicial en victimas de violencia de genero

espanolLa violencia de genero constituye una importante problematica social cuya investigacion es imprescindible para prevenirla y minimizar sus consecuencias. Nuestro estudio se centra en determinar la adecuacion de cuestionarios usados para la evaluacion de la depresion o la ansiedad que genera la violencia de genero en las victimas en el momento inicial de deteccion de la situacion. Se realizo un estudio descriptivo transversal con los datos de 93 mujeres victimas de violencia de genero, sin un perfil definido, que fueron evaluadas mediante las escalas de la desesperanza de Beck y Zung SAS previo a la celebracion del juicio rapido en los juzgados de violencia de genero de Madrid capital. Encontramos que las escalas de Zung SAS y Beck estan correlacionadas entre si (coeficiente de correlacion de Pearson: 0,6248) y pueden servir para determinar la presencia de depresion. Del estudio se desprende que las mujeres que han sufrido violencia de genero presentan cierto grado de depresion segun las pruebas analizadas. EnglishDomestic violence represents an important social problem that needs investigation to prevent it and minimize its consequences. Our investigation focuses on determining the adequacy of questionnaires used to evaluate depression or anxiety produced in domestic violence victims at the time of initial detection of the situation. A cross sectional descriptive study was carried out with 93 women victims of domestic violence selected randomly, without a defined profile, and were evaluated using Beck and Zung SAS Self Rating Anxiety/Depression Scale prior to the judicial process in the Courts of Gender Violence of Madrid. Zung SAS and Beck scales are correlated with each other (Pearson correlation coefficient 0.6248) and can be used to determine the presence of depression. Our study shows that women who have suffered gender violence have a degree of depression according to the tests we have studied.
Evaluation of Radiometric and Atmospheric Correction Algorithms for Aboveground Forest Biomass Estimation Using Landsat 5 TM Data
Venue: Remote. Sens.

Solar radiation is affected by absorption and emission phenomena during its downward trajectory from the Sun to the Earth's surface and during the upward trajectory detected by satellite sensors. This leads to distortion of the ground radiometric properties (reflectance) recorded by satellite images, used in this study to estimate aboveground forest biomass (AGB) Atmospherically corrected remote sensing data can be used to estimate AGB on a global scale and with moderate effort. The objective of this study was to evaluate four atmospheric correction algorithms (for surface reflectance) ATCOR2 (Atmospheric Correction for Flat Terrain) COST (Cosine of the Sun Zenith Angle) FLAASH (Fast Line of sight Atmospheric Analysis of Spectral Hypercubes) and 6S (Second Simulation of Satellite Signal in the Solar) and one radiometric correction algorithm (for reflectance at the sensor) ToA (Apparent Reflectance at the Top of Atmosphere) to estimate AGB in temperate forest in the northeast of the state of Durango, Mexico. The AGB was estimated from Landsat 5 TM imagery and ancillary information from a digital elevation model (DEM) using the non parametric multivariate adaptive regression splines (MARS) technique. Field reference data for the model training were collected by systematic sampling of 99 permanent forest growth and soil research sites (SPIFyS) established during the winter of 2011. The following predictor variables were identified in the MARS model: Band 7, Band 5, slope (b) Wetness Index (WI) NDVI and MSAVI2. After cross validation, 6S was found to be the optimal model for estimating AGB (R2 0.71 and RMSE 33.5 Mg*ha 1; 37.61% of the average stand biomass) We conclude that atmospheric and radiometric correction of satellite images can be used along with non parametric techniques to estimate AGB with acceptable accuracy.
Study of a Novel Equivalent Model and a Long Feeder Simulator Based Active Power Filter in a Closed Loop Distribution Feeder
Venue: IEEE Transactions on Industrial Electronics

The closed loop distribution system has become a trend, owing to increasing demands of electric power reliability in high tech parks or in metropolitan areas. Harmonic propagation caused by power factor correction capacitors and system inductors may lead to significant harmonic amplification throughout a closed loop distribution feeder. This paper proposes a novel equivalent model of a closed loop distribution feeder that a closed loop distribution feeder can be equivalent to a radial feeder. This paper analyzes the harmonic propagation in a closed loop distribution feeder and proposes a long feeder simulator based active power filter (LFS APF) to damp out the harmonic propagation, based on the novel equivalent model. The proposed LFS APF is installed at the middle point of a closed loop feeder. The LFS APF has better capability of harmonic damping than the resistive APF (RAPF) especially in response to variation of both nonlinear loads and power factor correction capacitors or even if the installation location has to deviate from the middle point. Both simulation and experiment results are provided to validate the correctness and effectiveness of the novel equivalent model and the proposed LFS APF.