nils-herrmann/clean_scirepeval huggingface dataset:
Designing Business Models for Creating and Capturing Shared Value: An Activity System Perspective

Business models define configurations of activities that jointly enable a firm to create and capture value. The value paradigm is shifting from sharing created value to creating shared value in which firms and societies jointly create and share value to nurture more benefits for a sustainable business environment symbiosis. Drawing on this logic, we develop a framework for designing business models that enable creation and capture of shared value. Our model builds on the practice theory and activity system and depicts business models as complex adaptive systems that co evolve with markets. Using the shared value framework proposed by Porter and Kramer (2011) we propose three design themes namely the Product Market Design (PMD) the Value Chain Design (VCD) and the Social Cluster Design (SCD) We specify features of each school from the activity perspective. Subsequently, we will discuss implications of our framework for theory, practice and management education and illuminate some directions for future research.
A dispute system design perspective on the future of European consumer dispute resolution

This chapter explores the concept of dispute system design in the context of consumer dispute resolution (CDR) While there is a growing literature on dispute system design (DSD) in North America, practitioners and scholars in the UK and Europe have failed to give significant attention to DSD as a discrete activity. As the role of CDR within civil justice systems across Europe continues to grow, the activity of 'designing justice' in this area should increasingly be seen as a matter of constitutional as well as practical significance. A failure to address this issue risks undermining the continued legitimacy of state sanctioned dispute resolution for consumer to business disputes. In this chapter, we present a new dispute design model for CDR mechanisms and, drawing on several case studies, demonstrate how it may be applied in practice.
Consensus statement for diagnosis of subcortical small vessel disease
Venue: Journal of cerebral blood flow and metabolism official journal of the International Society of Cerebral Blood Flow and Metabolism

Vascular cognitive impairment (VCI) is the diagnostic term used to describe a heterogeneous group of sporadic and hereditary diseases of the large and small blood vessels. Subcortical small vessel disease (SVD) leads to lacunar infarcts and progressive damage to the white matter. Patients with progressive damage to the white matter, referred to as Binswanger's disease (BD) constitute a spectrum from pure vascular disease to a mixture with neurodegenerative changes. Binswanger's disease patients are a relatively homogeneous subgroup with hypoxic hypoperfusion, lacunar infarcts, and inflammation that act synergistically to disrupt the blood brain barrier (BBB) and break down myelin. Identification of this subgroup can be facilitated by multimodal disease markers obtained from clinical, cerebrospinal fluid, neuropsychological, and imaging studies. This consensus statement identifies a potential set of biomarkers based on underlying pathologic changes that could facilitate diagnosis and aid patient selection for future collaborative treatment trials.
The impact of education on income inequality between ethnic minorities and Han in China

This article analyzes the impact of education on income inequality between ethnic minorities and Han in China by using the data from the China Health and Nutrition Survey (CHNS) over the period 1993 2011. An instrumental variable approach using two institutional changes is applied to address the endogeneity of education in income equations for various subsamples. To investigate the impact of education on income inequality between ethnic minorities and Han, we introduce an interaction term between the ethnic minority status and years of education. Our results suggest that there exists significant income inequality to the disadvantage of ethnic minorities for the full, female, and urban samples, and depending on the instrument also for the rural sample. Nevertheless, our results for these samples show specific returns to education for ethnic minorities, which implies that a portion of the income gap can be overcome with additional education. We find that in general one additional year of education will increase earned incomes of ethnic minorities by 26.3 28% and in particular by 13.5 14.4% for women from an ethnic minority group, by 10.4 14% for ethnic minorities with urban household registration, and by 10.8% for ethnic minorities with rural household registration. However, we cannot obtain conclusive results for the male sample due to weak instruments.
Perfil antropometrico y aptitud fisica en voleibolistas juveniles de colima

Primer lugar del area Rendimiento deportivo, categoria estudiante, en el Certamen Nacional de Investigacion en Cultura Fisica y Deporte 2015. Seudonimo Colima Voleibolero. El estudio de la presente investigacion corresponde al tipo cuantitativo descriptivo, que tiene como objetivo conocer la aptitud fisica y perfil antropometrico del jugador de voleibol juvenil del estado de Colima. La muestra esta integrada por 7 jugadores de la seleccion juvenil superior de dicha entidad. Para recuperar la informacion, se utilizo la tecnica antropometrica recomendada por la ISAK a traves de un perfil restringido y, en el caso de las pruebas fisicas, el protocolo fue integrado por las siguientes pruebas: salto vertical en gesto de ataque y bloqueo, velocidad en "T" Course Navette, Sit and Rich, Ruffier Dickson. Entre los resultados mas importantes, 14.3% de los jugadores obtuvo un somatotipo mesomorfo balanceado, 28.6% obtuvo ectomorfo mesomorfo, 28.6% obtuvo un somatotipo meso endomorfo y 14.3% un somatotipo central, dichos somatotipos no son los requeridos para el voleibol, mientras que el 14.3% restante obtuvo un somatotipo ecto mesomorfo clasificando como apto para el alto rendimiento en el voleibol. En cuanto a la composicion corporal, el tejido adiposo es aceptable; sin embargo, la masa muscular es deficiente y en lo relativo a la aptitud fisica, el equipo tiene un nivel promedio.
Open Lung Approach for the Acute Respiratory Distress Syndrome: A Pilot, Randomized Controlled Trial*
Venue: Critical care medicine

The open lung approach is a mechanical ventilation strategy involving lung recruitment and a decremental positive end expiratory pressure trial. We compared the Acute Respiratory Distress Syndrome network protocol using low levels of positive end expiratory pressure with open lung approach resulting in moderate to high levels of positive end expiratory pressure for the management of established moderate/severe acute respiratory distress syndrome. A prospective, multicenter, pilot, randomized controlled trial. A network of 20 multidisciplinary ICUs. Patients meeting the American European Consensus Conference definition for acute respiratory distress syndrome were considered for the study. At 12 36 hours after acute respiratory distress syndrome onset, patients were assessed under standardized ventilator settings (FIO2>=0.5, positive end expiratory pressure =10 cm H2O) If Pao2/FIO2 ratio remained less than or equal to 200 mm Hg, patients were randomized to open lung approach or Acute Respiratory Distress Syndrome network protocol. All patients were ventilated with a tidal volume of 4 to 8 ml/kg predicted body weight. From 1,874 screened patients with acute respiratory distress syndrome, 200 were randomized: 99 to open lung approach and 101 to Acute Respiratory Distress Syndrome network protocol. Main outcome measures were 60 day and ICU mortalities, and ventilator free days. Mortality at day 60 (29% open lung approach vs. 33% Acute Respiratory Distress Syndrome Network protocol, p 0.18, log rank test) ICU mortality (25% open lung approach vs. 30% Acute Respiratory Distress Syndrome network protocol, p 0.53 Fisher's exact test) and ventilator free days (8 [0 20] open lung approach vs. 7 [0 20] d Acute Respiratory Distress Syndrome network protocol, p 0.53 Wilcoxon rank test) were not significantly different. Airway driving pressure (plateau pressure positive end expiratory pressure) and PaO2/FIO2 improved significantly at 24, 48 and 72 hours in patients in open lung approach compared with patients in Acute Respiratory Distress Syndrome network protocol. Barotrauma rate was similar in both groups. In patients with established acute respiratory distress syndrome, open lung approach improved oxygenation and driving pressure, without detrimental effects on mortality, ventilator free days, or barotrauma. This pilot study supports the need for a large, multicenter trial using recruitment maneuvers and a decremental positive end expiratory pressure trial in persistent acute respiratory distress syndrome.
Design, development and clinical validation of a wrist based optical heart rate monitor
Venue: 2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)

Development in the field of sensor technology, hardware miniaturization, ubiquitous computing and connected solutions paved the way for the development of wearables for continuous physiological parameter monitoring. Continuous heart rate monitoring with clinical accuracy using reflectance photoplethysmogram signals from wrist is highly challenging and presents a potential area of research. In this work, we present a wearable device in a wrist watch form factor for heart rate monitoring. The device runs on a low power ARM cortex M4 microcontroller and integrates a BLE (Bluetooth Low energy) module for wireless connectivity. A heart rate computation algorithm using reflectance photoplethysmography and a 3 axes accelerometer for motion artifact removal is presented in the paper. Heart rate computed by the wrist worn device was validated against heart rate measured using Masimo Radical 7 on 256 subjects. The validation study was conducted in a hospital setting for a duration of 1 month, after obtaining the ethics committee approval and informed consent from the subjects. Details of the experimental setup, clinical validation protocol and observations and inferences made from the study are presented.
A semi implicit level set method for multiphase flows and fluid structure interaction problems
Venue: J. Comput. Phys.

In this paper we present a novel semi implicit time discretization of the level set method introduced in 8 for fluid structure interaction problems. The idea stems from a linear stability analysis derived on a simplified one dimensional problem. The semi implicit scheme relies on a simple filter operating as a pre processing on the level set function. It applies to multiphase flows driven by surface tension as well as to fluid structure interaction problems. The semi implicit scheme avoids the stability constraints that explicit scheme need to satisfy and reduces significantly the computational cost. It is validated through comparisons with the original explicit scheme and refinement studies on two dimensional benchmarks.
Building Bridges Toward Alternative Theory of Sustainable Supply Chain Management

We contend that the development of sustainable supply chain management (SSCM) theory has been impaired by a lack of paradigmatic diversity in the field. The contested nature of the concept of sustainability has been repressed in SSCM theory, which has led to SSCM cutting itself off from debates that could be the source of inspiration for the development of interesting theory. We adopt the problematization approach proposed by Alvesson and Sandberg (2011) in order to unveil some of SSCM's unquestioned assumptions, propose an alternative assumption ground, and in this way move toward stronger theory in SSCM. We use paradoxical framing to make sense of the inherent tensions between the different levels of sustainability and between the different types of theory being produced in response to the challenges of sustainability. We articulate a number of foundational assumptions for an alternative theory of SSCM that emerge from the various tensions identified between the different paradigms of sustainability. Finally, we identify a number of ideas for future research that would enable researchers to empirically explore the alternative assumptions.
A Distributed Representation Based Framework for Cross Lingual Transfer Parsing
Venue: J. Artif. Intell. Res.

This paper investigates the problem of cross lingual transfer parsing, aiming at inducing dependency parsers for low resource languages while using only training data from a resource rich language (e.g. English) Existing model transfer approaches typically don't include lexical features, which are not transferable across languages. In this paper, we bridge the lexical feature gap by using distributed feature representations and their composition. We provide two algorithms for inducing cross lingual distributed representations of words, which map vocabularies from two different languages into a common vector space. Consequently, both lexical features and nonlexical features can be used in our model for cross lingual transfer. Furthermore, our framework is flexible enough to incorporate additional useful features such as cross lingual word clusters. Our combined contributions achieve an average relative error reduction of 10.9% in labeled attachment score as compared with the delexicalized parser, trained on English universal treebank and transferred to three other languages. It also significantly outperforms state of the art delexicalized models augmented with projected cluster features on identical data. Finally, we demonstrate that our models can be further boosted with minimal supervision (e.g. 100 annotated sentences) from target languages, which is of great significance for practical usage.
An Efficient Cross lingual Model for Sentence Classification Using Convolutional Neural Network
Venue: ACL

In this paper, we propose a cross lingual convolutional neural network (CNN) model that is based on word and phrase embeddings learned from unlabeled data in two languages and dependency grammar. Compared to traditional machine translation (MT) based methods for cross lingual sentence modeling, our model is much simpler and does not need parallel corpora or language specific features. We only use a bilingual dictionary and dependency parser. This makes our model particularly appealing for resource poor languages. We evaluate our model using English and Chinese data on several sentence classification tasks. We show that our model achieves a comparable and even better performance than the traditional MT based method.
A Representation Learning Framework for Multi Source Transfer Parsing
Venue: AAAI

Cross lingual model transfer has been a promising approach for inducing dependency parsers for low resource languages where annotated treebanks are not available. The major obstacles for the model transfer approach are two fold: 1. Lexical features are not directly transferable across languages; 2. Target language specific syntactic structures are difficult to be recovered. To address these two challenges, we present a novel representation learning framework for multi source transfer parsing. Our framework allows multi source transfer parsing using full lexical features straightforwardly. By evaluating on the Google universal dependency tree banks (v2.0) our best models yield an absolute improvement of 6.53% in averaged labeled attachment score, as compared with delexicalized multi source transfer models. We also significantly outperform the state of the art transfer system proposed most recently.
All digital flexible uplink remote radio head for C RAN
Venue: 2016 IEEE MTT S International Microwave Symposium (IMS)

The Centralized Radio Access Networks (C RAN) are one of the current trends for the next generation mobile standards. The main concept of C RAN is the separation of the baseband processing and management tasks from the radio access units. This paper presents an all digital, simple and flexible RF uplink section for a C RAN Remote Radio Head (RRH) The implemented system presents an analog input bandwidth of about 3GHz, being capable to receive any signal up to 5MHz symbol rate while maintaining the current LTE Error Vector Magnitude (EVM) requirements.
Plasma EGFR T790M ctDNA status is associated with clinical outcome in advanced NSCLC patients with acquired EGFR TKI resistance
Venue: Scientific reports

EGFR T790M mutation occurs in half of non small cell lung cancer (NSCLC) patients with acquired EGFR TKI (TKI) resistance, based on tumor re biopsies using an invasive clinical procedure. Here, we dynamically monitored T790M mutation in circulating tumor DNA (ctDNA) using serial plasma samples from NSCLC patients receiving TKI through Droplet Digital PCR (ddPCR) method and the associations between overall survival (OS) starting from initial TKI treatment and the T790M ctDNA status detected in plasma were analyzed. Among 318 patients, 117 who acquired TKI resistance were eligible for the analysis. T790M ctDNA was detected in the plasma of 55/117 (47% patients. Almost half of the T790M ctDNA positive patients were identified at a median time of 2.2 months prior to clinically progressive disease (PD) Furthermore, within the patients receiving TKI treatment at 2nd line or later, the T790M ctDNA positive group had significantly shorter OS than the negative group (median OS: 26.9 months versus NA, P 0.0489) Our study demonstrates the feasibility of monitoring EGFR mutation dynamics in serial plasma samples from NSCLC patients receiving TKI therapy. T790M ctDNA can be detected in plasma before and after PD as a poor prognostic factor.
ctDNA Determination of EGFR Mutation Status in European and Japanese Patients with Advanced NSCLC: The ASSESS Study
Venue: Journal of thoracic oncology official publication of the International Association for the Study of Lung Cancer

To offer patients with EGFR mutation positive advanced NSCLC appropriate EGFR tyrosine kinase inhibitor treatment, mutation testing of tumor samples is required. However, tissue/cytologic samples are not always available or evaluable. The large, noninterventional diagnostic ASSESS study (NCT01785888) evaluated the utility of circulating free tumor derived DNA (ctDNA) from plasma for EGFR mutation testing.  ASSESS was conducted in 56 centers (in Europe and Japan) Eligible patients (with newly diagnosed locally advanced/metastatic treatment naive advanced NSCLC) provided diagnostic tissue/cytologic and plasma samples. DNA extracted from tissue/cytologic samples was subjected to EGFR mutation testing using local practices; designated laboratories performed DNA extraction/mutation testing of blood samples. The primary end point was level of concordance of EGFR mutation status between matched tissue/cytologic and plasma samples.  Of 1311 patients enrolled, 1288 were eligible. Concordance of mutation status in 1162 matched samples was 89% (sensitivity 46% specificity 97% positive predictive value 78% and negative predictive value 90% A group of 25 patients with apparent false positive plasma results was overrepresented for cytologic samples, use of less sensitive tissue testing methodologies, and smoking habits associated with high EGFR mutation frequency, indicative of false negative tumor results. In cases in which plasma and tumor samples were tested with identical highly sensitive methods, positive predictive value/sensitivity were generally improved.  These real world data suggest that ctDNA is a feasible sample for EGFR mutation analysis. It is important to conduct mutation testing of both tumor and plasma samples in specialized laboratories, using robust/sensitive methods to ensure that patients receive appropriate treatments that target the molecular features of their disease.
Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer
Venue: Oncotarget

Treatment of advanced colorectal cancer (CRC) requires multimodal therapeutic approaches and need for monitoring tumor plasticity. Liquid biopsy biomarkers, including CTCs and ctDNA, hold promise for evaluating treatment response in real time and guiding therapeutic modifications. From 15 patients with advanced CRC undergoing liver metastasectomy with curative intent, we collected 41 blood samples at different time points before and after surgery for CTC isolation and quantification using label free Vortex technology. For mutational profiling, KRAS, BRAF, and PIK3CA hotspot mutations were analyzed in CTCs and ctDNA from 23 samples, nine matched liver metastases and three primary tumor samples. Mutational patterns were compared. 80% of patient blood samples were positive for CTCs, using a healthy baseline value as threshold (0.4 CTCs/mL) and 81.4% of captured cells were EpCAM+ CTCs. At least one mutation was detected in 78% of our blood samples. Among 23 matched CTC and ctDNA samples, we found a concordance of 78.2% for KRAS, 73.9% for BRAF and 91.3% for PIK3CA mutations. In several cases, CTCs exhibited a mutation that was not detected in ctDNA, and vice versa. Complementary assessment of both CTCs and ctDNA appears advantageous to assess dynamic tumor profiles.
Ameliorer les interfaces entre achats, logistique et marketing l'humain au coeur de l'organisationnel

Les processus de creation de l'offre client, et plus largement les processus de creation de valeur, tendent de facon systematique a mettre l'accent sur l'importance des logiques d'action collectives, notamment dans le cadre de reseaux d'affaires. Sans remettre en question la pertinence de ces approches, l'article indique que le management des interfaces intra organisationnelles doit aujourd'hui etre replace au centre de l'analyse pour comprendre les fondements des mecanismes de la competitivite et accompagner au mieux les developpements inter organisationnels. La reflexion porte tout particulierement sur les echanges qui se nouent entre achats, logistique, et marketing, a partir d'une recherche exploratoire conduite aupres de dix entreprises. Il apparait que la qualite des relations humaines entre fonctions, ainsi qu'un dispositif organisationnel adapte, s'averent essentiels a l'accompagnement de la strategie d'entreprise.
The End of Cool Japan Ethical, Legal, and Cultural Challenges to Japanese Popular Culture

Negotiating "Cool Japan" in Research and Teaching Mark McLelland Death Note, Student Crimes, and the Power of Universities in the Global Spread of Manga Alisa Freedman Scholar Girl Meets Manga Maniac, Media Specialist, and Cultural Gatekeeper Laura Miller Must We Burn Eromanga? On Trying Obscenity in the Courtroom and the Classroom Kirsten Cather Manga, Anime and Child Pornography Law in Canada Sharalyn Orbaugh The "Lolicon Guy:" Some Observations on Researching Unpopular Topics in Japan Patrick W. Galbraith All Seizures Great and Small: Reading Contentious Images of Minors in Japan and Australia Adam Stapleton "The Love that Dare Not Speak its Name" Chinese Danmei Communities in the 2014 Anti Porn Campaign Lin Yang and Yanrui Xu Negotiating Religious and Fan Identities: "Boys Love" and Fujoshi Guilt Jessica Bauwens Sugimoto Is there a Space for Cool Manga in Indonesia and the Philippines? Postcolonial Discourses on Transcultural Manga Kristine Michelle Santos and Febriani  The Rise and Fall of the King of Lolicon: An Interview with Uchiyama Aki Patrick Galbraith