nils-herrmann/clean_scirepeval huggingface dataset:
Biological Effects of Medicinal Plants on Induced Periodontitis: A Systematic Review
Venue: International journal of dentistry

The aim of this systematic review was to investigate the advances in the study of medicinal plants and their biologic effects on periodontitis in animal models.  A systematic search was conducted by three independent researchers, who screened articles published up to March/2016, to identify the studies that contained sufficient and clear information on the association of the medicinal plants and periodontitis in murine models. The searches were performed using PubMed, Cochrane, and Science Direct databases.  After a critical analysis of titles and abstracts, 30 studies were finally eligible for analysis. The studies presented a great diversity of the experiment designed regarding the methods of induced periodontitis and the evaluation of the medicinal plants efficacy. None of the studies described the possible toxic effects associated with the administration of the plant material to animals and whether they could prevent damage to organs caused by systemic effect of induced periodontitis. Gel based formulations containing plant substances are seen as an interesting strategy to treat periodontitis.  In this systematic review, the state of the art knowledge on the medicinal plants and the induced periodontitis was critically evaluated and discussed from the experiment designed to the possible clinical application.
Highly sensitive and wide dynamic range liquid prism surface plasmon resonance refractive index sensor based on the phase and angular interrogations

In this study, a new method utilizing surface plasmon resonance (SPR) sensing technology based on the phase and angular interrogations for measuring the refractive index of a liquid prism is presented. An orthogonal sample box that combined the functions of a prism, cell box, and mirror is adopted to simplify the system and provide the convenience to implement the phase and angular interrogations. The angular interrogation is achieved by the motorized rotation stage with the new sample box, and the phase interrogation is achieved by the linear polarization interferometry between the s and p polarization components. The amplitude reflectivity and the phase angle, which are the functions of the incident angle, are obtained by the reflection intensity and the interference intensity of the lights directly. A sensitivity of 7.5x10 7 refractive index unit (RIU)/0.1deg and a dynamic range of 0.5 RIU are obtained experimentally and theoretically.
"Gay in the Bank, Queer in the Streets" The Intersection of LGBTQQ and Social Class Identities

Calls from the counseling literature have highlighted a need for the examination of intersections between marginalized identities and identities of social class. This article investigates the intersection of lesbian, gay, bisexual, transgender, queer, questioning (LGBTQQ) identity and social class. The authors review current literature and scholarship on these intersections, identify key issues between the intersection of these two identities, and discuss critical strategies for counselors to engage with the intersection of social class and LGBTQQ identities. Recommendations for counseling research, training, practice, and advocacy are discussed.
FcgRIIb SHIP2 axis links Ab to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model
Venue: eLife

Amyloid b (Ab) containing extracellular plaques and hyperphosphorylated tau loaded intracellular neurofibrillary tangles are neuropathological hallmarks of Alzheimer's disease (AD) Although Ab exerts neuropathogenic activity through tau, the mechanistic link between Ab and tau pathology remains unknown. Here, we showed that the FcgRIIb SHIP2 axis is critical in Ab1 42 induced tau pathology. Fcgr2b knockout or antagonistic FcgRIIb antibody inhibited Ab1 42 induced tau hyperphosphorylation and rescued memory impairments in AD mouse models. FcgRIIb phosphorylation at Tyr273 was found in AD brains, in neuronal cells exposed to Ab1 42, and recruited SHIP2 to form a protein complex. Consequently, treatment with Ab1 42 increased PtdIns(3,4)P2 levels from PtdIns(3,4,5)P3 to mediate tau hyperphosphorylation. Further, we found that targeting SHIP2 expression by lentiviral siRNA in 3xTg AD mice or pharmacological inhibition of SHIP2 potently rescued tau hyperphosphorylation and memory impairments. Thus, we concluded that the FcgRIIb SHIP2 axis links Ab neurotoxicity to tau pathology by dysregulating PtdIns(3,4)P2 metabolism, providing insight into therapeutic potential against AD.
An Efficient Implementation of the Bellman Ford Algorithm for Kepler GPU Architectures
Venue: IEEE Transactions on Parallel and Distributed Systems

Finding the shortest paths from a single source to all other vertices is a common problem in graph analysis. The Bellman Ford's algorithm is the solution that solves such a single source shortest path (SSSP) problem and better applies to be parallelized for many core architectures. Nevertheless, the high degree of parallelism is guaranteed at the cost of low work efficiency, which, compared to similar algorithms in literature (e.g. Dijkstra's) involves much more redundant work and a consequent waste of power consumption. This article presents a parallel implementation of the Bellman Ford algorithm that exploits the architectural characteristics of recent GPU architectures (i.e. NVIDIA Kepler, Maxwell) to improve both performance and work efficiency. The article presents different optimizations to the implementation, which are oriented both to the algorithm and to the architecture. The experimental results show that the proposed implementation provides an average speedup of <inline formula><tex math notation="LaTeX"$5 \times$ /tex math><alternatives><inline graphic xlink:type="simple" xlink:href="bombieri ieq1 2485994.gif"/alternatives>/inline formula> higher than the existing most efficient parallel implementations for SSSP, that it works on graphs where those implementations cannot work or are inefficient (e.g. graphs with negative weight edges, sparse graphs) and that it sensibly reduces the redundant work caused by the parallelization process.
Linking Natural Modeling to Techno centric Modeling for the Active Involvement of Process Participants in Business Process Design
Venue: Int. J. Inf. Syst. Model. Des.

Actively involving participants in business process modeling enables integration between elicitation and modeling steps of the BPM lifecycle. Such integration may lead to a more efficient design procedure and ultimately to a more accurate representation of the business process. However, active involvement of process participants creates several challenges, as the latter are not expected to have modeling skills. The purpose of this paper is to present a business process design approach, called CoMPArE /WP, which tightly integrates the elicitation and modeling stages of process design, through the active involvement of process participants. To achieve effective involvement of process participants, CoMPArE/WP adopts the principles of natural modeling. However, being a business process design approach aiming at supporting the whole BPM lifecycle, CoMPArE /WP deals also with the transition of natural modeling to formal process representations that can be enacted using a BPMS.
Electrochemical determination of activity of acetylcholinesterase immobilized on magnetic particles

Acetylcholinesterasa (AChE) je enzym ukoncujici prenos vzruchu v cholinergnim systemu. Aktivita enzymu se bezne vysetruje Ellmanovou metodou, ktera ma ovsem nedostatky jako je nestabilita pouzitych reagencii. Dalsi nevyhodou je neschopnost vyuzit enzym znovu. Proto jsme vyvinuli proces vyuzivajici EDC pro imobilizaci AChE na povrch magnetickych castic, ktere nabizeji moznost separovat enzym a znovu jej vyuzit. Pro stanoveni enzyove aktivity jsme optimalizovali metodu square wave voltametrie za pouziti tistenych elektrod modifikovanych Pruskou modri. Pro testovany inhibitor AChE, takrin, jsme ziskali detekcni limit 8,1 mM. V porovnani se standardni Ellmanovou metodou, imobilizovany enzym ma limitovanou citlivost k organickym rozpoustedlum.
Higher education and the digital revolution: About MOOCs, SPOCs, social media, and the Cookie Monster

Distance learning that is, providing education to students who are separated by distance and in which the pedagogical material is planned and prepared by educational institutions is a topic of regular interest in the popular and business press. In particular, MOOCs (Massive Open Online Courses) which are open access online courses that allow for unlimited participation, as well as SPOCs (Small Private Online Courses) are said to have revolutionized universities and the corporate education landscape. In this article we provide a nuanced analysis of the phenomenon of online distance learning. We first provide an overview of its historical evolution, and subsequently define and classify key concepts. We further discuss in detail the optimal target group in terms of participating students and teaching professors and propose corresponding frameworks for driving intrinsic student motivation and for choosing a successful online teacher. We also outline the benefits that institutions can achieve by offering online distance learning. Finally, we speak about the specific connection between online distance learning and social media by focusing on the difference between MOOCs based on traditional lecture formats (xMOOCs) and connectivist cMOOCs.
Investment in Electricity Generation and Transmission: Decision Making under Uncertainty

(c) Springer International Publishing Switzerland 2016. This book provides an in depth analysis of investment problems pertaining to electric energy infrastructure, including both generation and transmission facilities. The analysis encompasses decision making tools for expansion planning, reinforcement, and the selection and timing of investment options. In this regard, the book provides an up to date description of analytical tools to address challenging investment questions such as: How can we expand and/or reinforce our aging electricity transmission infrastructure? How can we expand the transmission network of a given region to integrate significant amounts of renewable generation? How can we expand generation facilities to achieve a low carbon electricity production system? How can we expand the generation system while ensuring appropriate levels of flexibility to accommodate both demand related and production related uncertainties? How can we choose among alternative production facilities? What is the right time to invest in a given production or transmission facility? Written in a tutorial style and modular format, the book includes a wealth of illustrative examples to facilitate comprehension. It is intended for advanced undergraduate and graduate students in the fields of electric energy systems, operations research, management science, and economics. Practitioners in the electric energy sector will also benefit from the concepts and techniques presented here.
The diffusion of the learning pyramid myths in academia: an exploratory study

This article examines the diffusion and present day status of a family of unsubstantiated learning retention myths, some of which are referred to as 'the learning pyramid' We demonstrate through an extensive search in academic journals and field specific encyclopaedias that these myths are indeed widely publicised in academia and that they have gained a considerable level of authority. We also argue that the academic publishing of these myths is potentially harmful to both professional as well as political deliberations on educational issues, and therefore should be criticized and counteracted.
Do job fairs matter? Experimental evidence on the impact of job fair attendance

I estimate the causal impact of attending a job fair on employment outcomes and labor market perceptions, using a randomized encouragement design to induce individuals in the rural Philippines to attend a nearby job fair for domestic and overseas work. Attending a job fair matters: though it does not facilitate direct matches with a job fair employer, attendance leads to a large increase in reported formal sector employment and in the likelihood of looking for any work outside the region in the months following the job fair. Several overseas recruitment agencies participated in the job fair, and attendance affects individuals' overseas labor market perceptions but does not encourage them to take steps to migrate. These results suggest that job fairs can be important tools for encouraging individuals to move to the formal sector and for conveying information about labor market prospects.
Improving human robot interaction based on joint attention
Venue: Applied Intelligence

The current study proposes a novel cognitive architecture for a computational model of the limbic system, inspired by human brain activity, which improves interactions between a humanoid robot and preschool children using joint attention during turn taking gameplay. Using human robot interaction (HRI) this framework may be useful for ameliorating problems related to attracting and maintaining attention levels of children suffering from attention deficit hyperactivity disorder (ADHD) In the proposed framework, computational models including the amygdala, hypothalamus, hippocampus, and basal ganglia are used to simulate a range of cognitive processes such as emotional responses, episodic memory formation, and selection of appropriate behavioral responses. In the currently proposed model limbic system, we applied reinforcement and unsupervised learning based adaptation processes to a dynamic neural field model, resulting in a system that was capable of observing and controlling the physical and cognitive processes of a humanoid robot. Several interaction scenarios were tested to evaluate the performance of the model. Finally, we compared the results of our methodology with a neural mass model.
Combat PTSD and Implicit Behavioral Tendencies for Positive Affective Stimuli: A Brief Report
Venue: Front. Psychol.

Prior cognitive research in posttraumatic stress disorder (PTSD) has focused on automatic responses to negative affective stimuli, including attentional facilitation or disengagement and avoidance action tendencies. More recent research suggests PTSD may also relate to differences in reward processing, which has lead to theories of PTSD relating to approach avoidance imbalances. The current pilot study assessed how combat PTSD symptoms relate to automatic behavioral tendencies to both positive and negative affective stimuli.  Twenty male combat veterans completed the approach avoidance task (AAT) Clinician Administered PTSD Scale, Beck Depression Inventory II, and State Trait Anger Expression Inventory II. During the AAT, subjects pulled (approach) or pushed (avoid) a joystick in response to neutral, happy, disgust, and angry faces based on border color. Bias scores were calculated for each emotion type (avoid approach response latency differences) Main and interaction effects for psychological symptom severity and emotion type on bias score were assessed using linear mixed models.  There was a significant interaction between PTSD symptoms and emotion type, driven primarily by worse symptoms relating to a greater bias to avoid happy faces. Post hoc tests revealed that veterans with worse PTSD symptoms were slower to approach as well as quicker to avoid happy faces. Neither depressive nor anger symptoms related to avoid or approach tendencies of emotional stimuli.  Posttraumatic stress disorder severity was associated with a bias for avoiding positive affective stimuli. These results provide further evidence that PTSD may relate to aberrant processing of positively valenced, or rewarding stimuli. Implicit responses to rewarding stimuli could be an important factor in PTSD pathology and treatment. Specifically, these findings have implications for recent endeavors in using computer based interventions to influence automatic approach avoidance tendencies.
Diet Microbiota Interactions Mediate Global Epigenetic Programming in Multiple Host Tissues.
Venue: Molecular cell

Histone modifying enzymes regulate transcription and are sensitive to availability of endogenous small molecule metabolites, allowing chromatin to respond to changes in environment. The gut microbiota produces a myriad of metabolites that affect host physiology and susceptibility to disease; however, the underlying molecular events remain largely unknown. Here we demonstrate that microbial colonization regulates global histone acetylation and methylation in multiple host tissues in a diet dependent manner: consumption of a "Western type" diet prevents many of the microbiota dependent chromatin changes that occur in a polysaccharide rich diet. Finally, we demonstrate that supplementation of germ free mice with short chain fatty acids, major products of gut bacterial fermentation, is sufficient to recapitulate chromatin modification states and transcriptional responses associated with colonization. These findings have profound implications for understanding the complex functional interactions between diet, gut microbiota, and host health.
APLIKASI SIX SIGMA DMAIC DAN KAIZEN SEBAGAI METODE PENGENDALIAN DAN PERBAIKAN KUALITAS PRODUK PT. SARANDI KARYA NUGRAHA

PT. Sarandi Karya Nugraha adalah perusahaan yang bergerak dalam bidang kesehatan dengan hasil produksi berupa peralatan dan furniture rumah sakit yaitu emergency trolley. Dalam menghasilkan produksinya rata rata per bulan terdapat produk cacat sebesar 12,84% Maka dari itu penelitian ini digunakan untuk mengetahui kemampuan proses berdasarkan produk cacat yang ada dengan metode DMAIC dan pendekatan six sigma yang kemudian dilakukan pengendalian dengan menganalisis penyebab kecacatan menggunakan Seven Tools serta mengupayakan perbaikan berkesinambungan dengan alat implementasi kaizen berupa Kaizen Five Step Plan, 5W dan 1H, dan Five M Checklist. Setelah dilakukan pengolahan data didapat nilai DPMO sebesar 29.043,41 yang dapat diartikan bahwa dari satu juta kesmpatan akan terdapat 29.043,41 kemungkinan produk yang dihasilkan mengalami kecacatan. Perusahaan berada pada tingkat 3,39 sigma dengan CTQ (Critical To Quality) yang paling banyak menimbulkan cacat yaitu cat kasar sebesar 46,5% dari total cacat 7490. Dari hasil analisis berdasarkan alat alat implementasi kaizen maka kebijakan utama yang harus dijalankan oleh pihak perusahaan yaitu pengawasan atau kontrol yang lebih ketat di segala bidang.  DMAIC AND KAIZEN AS A CONTROL METHOD AND QUALITY IMPROVEMENT PRODUCTS at PT. Sarandi Karya Nugraha. PT. Sarandi Karya Nugraha is a company that engaged in health equipment and produce a hospital furniture, such as emergency trolley. In producing an average production per month, the defective product was 12.84% This research is used to determine the ability of the process based on product defects that exist with the approach of six sigma then be controlled by analyzing the causes of disability using the Seven Tools and seeking continuous improvement by implementing Kaizen Five Step Plan, 5W and 1H, and the Five M checklist. After processing the data, obtained DPMO value of 29043.41 which means that from one million opportunity there will be the possibility of disability product produced as much as 29043.41. The Company is at 3.39 sigma level with CTQ (Critical To Quality) most coarse cause paint defects that 46.5% of the total disability 7490. From the analysis by means of the implementation of kaizen, the main policies that should be run by the companies that tighten controls in all areas.
Influence of Transformational Leadership on Discipline Management and Academic Performance of Student Nurses in Kenya Medical Training Colleges in Kenya

The purpose of the study was to determine the influence of transformational leadership on discipline and academic performance of nursing students in medical training colleges in Kenya. The study population comprised of 7740 student nurses, 640 nurse tutors and 41 medical training colleges. Purposive sampling was used to select four medical training colleges. The study used a sample of 475 student nurses, 36 nurse tutors and 4 principals. Questionnaires were used to collect data. The data was analysed using descriptive and inferential statistics. The study concluded that the principals were not satisfied with their autonomy in decision making. The nurse tutors were demotivated according to students nurses because nurse tutors are not performing to their expectations. The principals in the study were not satisfied with the autonomy they are given to make decisions and this led the principals not to implement a discipline programme leading to many types of indiscipline; caring personality led to them not to treat their nurse tutors and students as unique individuals while those who don't know their purpose in the medical training failed their examinations and were discontinued or they were discontinued because of indiscipline cases. It is recommended that principals should implement electronic class attendance systems. The principals should also benchmark, develop and implement an elaborate discipline policy to improve the transition rates from admission to graduation.
Sensified Gaming: Design Patterns and Game Design Elements for Gameful Environmental Sensing
Venue: ACE

Participatory Sensing, i.e. collaboratively taking sensor measurements with mobile devices in a Citizen Science fashion, has become increasingly popular. Because such scenarios often require a critical mass of users, applying gamification to different areas in order to increase user engagement has been proposed. However, existing attempts often default to the standard points, badges, and leaderboards and fail to recognize the potential of exploiting game design elements beyond creating user engagement. We propose not to think of Gamified Participatory Sensing when designing such systems, but rather of Sensified Gaming. To this end, this work presents a collection of design patterns and game mechanics that can be used to identify or design suitable games, into which participatory sensing tasks can be embedded. We identified four core tasks from participatory environmental sensing and sensor networks research, reviewed hundreds of design patterns and map each of the 63 selected patterns to the core tasks.