nils-herrmann/clean_scirepeval huggingface dataset:
Rare compound heterozygosity involving dominant and recessive mutations of GJB2 gene in an assortative mating hearing impaired Indian family
Venue: European Archives of Oto Rhino Laryngology

Connexin 26 (Cx 26) a gap junction protein coded by GJB2 gene, plays a very important role in recycling of potassium ions, one of the vital steps in the mechanotransduction process of hearing. Mutations in the GJB2 gene have been associated with both autosomal recessive as well as dominant nonsyndromic hearing loss. As Cx 26 is linked with skin homeostasis, mutations in this gene are sometimes associated with syndromic forms of hearing loss showing skin anomalies. We report here a non consanguineous assortatively mating hearing impaired family with one of the hearing impaired partners, their hearing impaired sibling and hearing impaired offspring showing compound heterozygosity in the GJB2 gene, involving a dominant mutation p.R184Q and two recessive mutations p.Q124X and c.IVS 1+1G>A in a unique triallelic combination. To the best of our knowledge, this is the first report from India on p.R184Q mutation in the GJB2 gene associated with rare compound heterozygosity showing nonsyndromic presentation.
Distributed learning particle swarm optimizer for global optimization of multimodal problems
Venue: Frontiers of Computer Science

Particle swarm optimizer (PSO) is an effective tool for solving many optimization problems. However, it may easily get trapped into local optimumwhen solving complex multimodal nonseparable problems. This paper presents a novel algorithm called distributed learning particle swarm optimizer (DLPSO) to solve multimodal nonseparable problems. The strategy for DLPSO is to extract good vector information from local vectors which are distributed around the search space and then to form a new vector which can jump out of local optima and will be optimized further. Experimental studies on a set of test functions show that DLPSO exhibits better performance in solving optimization problems with few interactions between variables than several other peer algorithms.
In situ Doping and Local Overcompensation of High Performance LPCVD Polysilicon Passivated Contacts as Approach to Industrial IBC Cells

In this work, we investigate polysilicon passivation contacts, to be used for high performance IBC cells. We demonstrate an LPCVD process for in situ p type doped polysilicon. The p type polysilicon can be locally overcompensated to n type polysilicon using phosphorous implantation or POCl 3 diffusion. Both contacts show excellent surface passivation, with recombination current (J o of 12 fA/cm 2 for p poly on a polished Si surface, and less than 10 fA/cm 2 for compensated n poly both on textured and polished surfaces. These polysilicon layers are implemented in the fabrication of n PERT cells with front and rear polysilicon contacts. The resulting textured half fabricated cells have an implied V oc of 701 mV after hydrogenation via PECVD deposition of SiN x :H. Different metallization processes, relevant for IBC cells, are applied. A V oc of 685 mV is obtained for the best cell metallized with low temperature metallization (ITO/low temperature Ag paste) and 678 mV is obtained for the best cell with industrial screen printed firing through contacts. In these n PERT cells the same thin oxide layer is used for p type and n type polysilicon contacts.
Multiparty Key Exchange, Efficient Traitor Tracing, and More from Indistinguishability Obfuscation
Venue: Algorithmica

In this work, we show how to use indistinguishability obfuscation to build multiparty key exchange, efficient broadcast encryption, and efficient traitor tracing. Our schemes enjoy several interesting properties that have not been achievable before:Our multiparty non interactive key exchange protocol does not require a trusted setup. Moreover, the size of the published value from each user is independent of the total number of users.Our broadcast encryption schemes support distributed setup, where users choose their own secret keys rather than be given secret keys by a trusted entity. The broadcast ciphertext size is independent of the number of users.Our traitor tracing system is fully collusion resistant with short ciphertexts, secret keys, and public key. Ciphertext size is logarithmic in the number of users and secret key size is independent of the number of users. Our public key size is polylogarithmic in the number of users. The recent functional encryption system of Garg, Gentry, Halevi, Raykova, Sahai, and Waters also leads to a traitor tracing scheme with similar ciphertext and secret key size, but the construction in this paper is simpler and more direct. These constructions resolve an open problem relating to differential privacy.Generalizing our traitor tracing system gives a private broadcast encryption scheme (where broadcast ciphertexts reveal minimal information about the recipient set) with optimal size ciphertext. Several of our proofs of security introduce new tools for proving security using indistinguishability obfuscation.
Christology And Cosmology Models Of Divine Activity In Origen Eusebius And Athanasius

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Development of ORIGEN libraries for mixed oxide (MOX) fuel assembly designs

In this research, ORIGEN cross section libraries for reactor grade mixed oxide (MOX) fuel assembly designs have been developed to provide fast and accurate depletion calculations to predict nuclide inventories, radiation sources and thermal decay heat information needed in safety evaluations and safeguards verification measurements of spent nuclear fuel. These ORIGEN libraries are generated using two dimensional lattice physics assembly models that include enrichment zoning and cross section data based on ENDF/B VII.0 evaluations. Using the SCALE depletion sequence, burnup dependent cross sections are created for selected commercial reactor assembly designs and a representative range of reactor operating conditions, fuel enrichments, and fuel burnup. The burnup dependent cross sections are then interpolated to provide problem dependent cross sections for ORIGEN, avoiding the need for time consuming lattice physics calculations. The ORIGEN libraries for MOX assembly designs are validated against destructive radiochemical assay measurements of MOX fuel from the MALIBU international experimental program. This program included measurements of MOX fuel from a 15 x 15 pressurized water reactor assembly and a 9 x 9 boiling water reactor assembly. The ORIGEN MOX libraries are also compared against detailed assembly calculations from the Phase IV B numerical MOX fuel burnup credit benchmark coordinated by the Nuclear Energy Agency within themore Organization for Economic Cooperation and Development. Finally, the nuclide compositions calculated by ORIGEN using the MOX libraries are shown to be in good agreement with other physics codes and with experimental data.
Erasmus's Life of Origen: A New Annotated Translation of the Prefaces to Erasmus of Rotterdam's Edition of Origen's Writings (1536)

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Genetic dissection of flour whiteness by unconditional and conditional quantitative trait locus mapping in wheat
Venue: The Journal of Agricultural Science

Flour whiteness (FW) is an important factor in assessing flour quality and determining the end product quality. It is an integrated sensory indicator reflecting flour colour and is negatively correlated with protein content. In order to dissect the genetic relationship between FW and its five related traits at the quantitative trait locus (QTL)/gene level, a recombinant inbred line population was evaluated under three environments. Quantitative trait loci for FW were analysed by unconditional and conditional QTL mapping. Four unconditional additive QTLs and 16 conditional additive QTLs were detected across the three environments. Of these QTLs, only one major additive QTL (Qfw1D1 1) was consistently identified using both unconditional and conditional QTL analysis. This QTL was independent of flour colour a* (a function of red green with a positive a* for redness and negative for greenness) and b* (a green blue value with positive value for yellowness and negative for blueness) and was only slightly affected by flour protein content. A minor additive QTL (Qfw4A 4) was also detected using these two QTL mapping methods, being independent of flour colour a* and b* Five unconditional and ten conditional epistatic minor QTLs were detected, from which only one pair (Qfw3A 10/Qfw6B 6) was identified by both unconditional and conditional QTL mapping, also independent of flour colour a* and b* The major QTL (Qfw1D1 1) identified in the current study for the first time can be used for improving wheat FW in marker assisted breeding.
Interpretation of the ICESCR: Between Morality and State Consent

Discussions concerning the interpretive practice of the Committee on Economic, Social and Cultural Rights have so far centred on the question as to the legality of the 'special' interpretive techniques and tools which it has developed: Does the special nature of the ICESCR as a human rights treaty justify recourse to interpretive methods that may not be covered by Articles 31 33 of the VCLT? This paper argues that the VCLT's interpretive framework also applies to human rights treaties and is broad enough to accommodate the Committee's methods which, on closer inspection, turn out to be not that special at all. The key question is not whether there is a legal basis for the interpretive methods employed by the Committee there clearly is but, instead, whether its interpretations are regarded as legitimate. For the Committee, legitimacy seems to boil down to sufficient state support. Accordingly, its interpretive practice is informed by constant attempts to find the right balance between its urge to give the Covenant a moral reading and establishing common ground among states parties. Yet the legitimacy of a given interpretation depends on more than the extent of (pre existing) state consensus it reflects. Legitimacy can be generated through following a process of interpretation that the interpretive community regards as adequate and fair and that produces interpretive outcomes that appear persuasive to it. For an interpretive practice to be legitimate, it will be argued, the interpreter must adhere to an agreed upon set of principles and apply it in a coherent and transparent manner.
A Dynamic Recurrent Model for Next Basket Recommendation
Venue: SIGIR

Next basket recommendation becomes an increasing concern. Most conventional models explore either sequential transaction features or general interests of users. Further, some works treat users' general interests and sequential behaviors as two totally divided matters, and then combine them in some way for next basket recommendation. Moreover, the state of the art models are based on the assumption of Markov Chains (MC) which only capture local sequential features between two adjacent baskets. In this work, we propose a novel model, Dynamic REcurrent bAsket Model (DREAM) based on Recurrent Neural Network (RNN) DREAM not only learns a dynamic representation of a user but also captures global sequential features among baskets. The dynamic representation of a specific user can reveal user's dynamic interests at different time, and the global sequential features reflect interactions of all baskets of the user over time. Experiment results on two public datasets indicate that DREAM is more effective than the state of the art models for next basket recommendation.
The Whale Optimization Algorithm
Venue: Adv. Eng. Softw.

The Whale Optimization Algorithm inspired by humpback whales is proposed.The WOA algorithm is benchmarked on 29 well known test functions.The results on the unimodal functions show the superior exploitation of WOA.The exploration ability of WOA is confirmed by the results on multimodal functions.The results on structural design problems confirm the performance of WOA in practice. This paper proposes a novel nature inspired meta heuristic optimization algorithm, called Whale Optimization Algorithm (WOA) which mimics the social behavior of humpback whales. The algorithm is inspired by the bubble net hunting strategy. WOA is tested with 29 mathematical optimization problems and 6 structural design problems. Optimization results prove that the WOA algorithm is very competitive compared to the state of art meta heuristic algorithms as well as conventional methods. The source codes of the WOA algorithm are publicly available at http:/www.alimirjalili.com/WOA.html
Robust Facial Landmark Detection via Recurrent Attentive Refinement Networks
Venue: ECCV

In this work, we introduce a novel Recurrent Attentive Refinement (RAR) network for facial landmark detection under unconstrained conditions, suffering from challenges like facial occlusions and/or pose variations. RAR follows the pipeline of cascaded regressions that refines landmark locations progressively. However, instead of updating all the landmark locations together, RAR refines the landmark locations sequentially at each recurrent stage. In this way, more reliable landmark points are refined earlier and help to infer locations of other challenging landmarks that may stay with occlusions and/or extreme poses. RAR can thus effectively control detection errors from those challenging landmarks and improve overall performance even in presence of heavy occlusions and/or extreme conditions. To determine the sequence of landmarks, RAR employs an attentive refinement mechanism. The attention LSTM (A LSTM) and refinement LSTM (R LSTM) models are introduced in RAR. At each recurrent stage, A LSTM implicitly identifies a reliable landmark as the attention center. Following the sequence of attention centers, R LSTM sequentially refines the landmarks near or correlated with the attention centers and provides ultimate detection results finally. To further enhance algorithmic robustness, instead of using mean shape for initialization, RAR adaptively determines the initialization by selecting from a pool of shape centers clustered from all training shapes. As an end to end trainable model, RAR demonstrates superior performance in detecting challenging landmarks in comprehensive experiments and it also establishes new state of the arts on the 300 W, COFW and AFLW benchmark datasets.
A systematic review of observational studies evaluating costs of adverse drug reactions
Venue: ClinicoEconomics and outcomes research CEOR

The growing evidence of the increased frequency and severity of adverse drug events (ADEs) besides the negative impact on patient's health status, indicates that costs due to ADEs may be steadily rising. Observational studies are an important tool in pharmacovigilance. Despite these studies being more susceptible to bias than experimental designs, they are more competent in assessing ADEs and their associated costs.  To identify and characterize the best available evidence on ADE associated costs.  MEDLINE, Cochrane Library, and Embase were searched from 1995 to 2015. Observational studies were included. The methodological quality of selected studies was assessed by Cochrane Collaboration tool for experimental and observational studies. Studies were classified according to the setting analyzed in "ambulatory" "hospital" or both. Costs were classified as "direct" and "indirect" Data were analyzed using descriptive statistics. The total incremental cost per patient with ADE was estimated.  Twenty nine (94% longitudinal observational studies and two (7% cross sectional studies were included. Twenty three (74% studies were assessed with the highest methodological quality score. The studies were mainly conducted in the US (61% Twenty (65% studies evaluated any therapeutic group. Twenty (65% studies estimated costs of ADEs leading to or prolonging hospitalization. The "direct costs" were evaluated in all studies, whereas only two (7% also estimated the "indirect costs" The "direct costs" in ambulatory ranged from EUR702.21 to EUR40,273.08, and the in hospital from EUR943.40 to EUR7,192.36.  Methodological heterogeneities were identified among the included studies, such as design, type of ADEs, suspected drugs, and type and structure of costs. Despite such discrepancies, the financial burden associated with ADE costs was found to be high. In the light of the present findings, validated methods to measure ADE associated costs need future research efforts.
Investigating the epidemiology of medication errors and error related adverse drug events (ADEs) in primary care, ambulatory care and home settings: a systematic review protocol
Venue: BMJ Open

There is a need to better understand the epidemiology of medication errors and error related adverse events in community care contexts.  We will systematically search the following databases: Cumulative Index to Nursing and Allied Health Literature (CINAHL) EMBASE, Eastern Mediterranean Regional Office of the WHO (EMRO) MEDLINE, PsycINFO and Web of Science. In addition, we will search Google Scholar and contact an international panel of experts to search for unpublished and in progress work. The searches will cover the time period January 1990 December 2015 and will yield data on the incidence or prevalence of and risk factors for medication errors and error related adverse drug events in adults living in community settings (ie, primary care, ambulatory and home) Study quality will be assessed using the Critical Appraisal Skills Program quality assessment tool for cohort and case control studies, and cross sectional studies will be assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Descriptive Studies. Meta analyses will be undertaken using random effects modelling using STATA (V.14) statistical software. Ethics and dissemination This protocol will be registered with PROSPERO, an international prospective register of systematic reviews, and the systematic review will be reported in the peer reviewed literature using Preferred Reporting Items for Systematic Reviews and Meta Analyses.
Is mindfulness a mediator factor in obsessive compulsive disorder

The aim of this study was to determine the effectiveness of mindfulness based cognitive therapy (MBCT) on positive reappraisal in patients suffering from obsessive compulsive disorder (OCD)  The research design was quasi experimental of pre test and post test type with control group. The statistical population of present study involved all patients referring to psychiatry clinics of Tabriz University of Medical Sciences who received obsessive compulsive disorders diagnosis. Thirty available patients were selected that filled cognitive emotion regulation questionnaire (CERQ) after being randomly assigned to experimental and control groups. The experimental group attended 8 sessions of MBCT. The cognitive emotional regulation questioner was administered after completion of the sessions and data of both states (before and after sessions) were collected and analyzed using covariance analysis test.  The MBCT was effective in increasing positive strategies (positive reappraisal, positive refocusing, planning, putting into perspective) and decreasing negative strategies (self blame, blaming others, catastrophizing, rumination, and acceptance) in patients with obsessive compulsive disorder (P<0.05)  This study indicated that it is possible to increase positive strategies of emotion regulation through training MBCT.
Pengaruh Penggunaan Aromaterapi Cendana dengan Teknik Vaporizer terhadap Prilaku Agresif Anak Tunagrahita

Dalam pandangan biologis, prilaku agresif dapat disebabkan oleh produksi serotonin yang rendah. Penggunaan aromaterapi cendana dengan teknik vaporizer disamping mampu meningkatkan produksi serotonin, juga mampu menghindari kebosanan, mengatasi masalah emosi, sehingga prilaku agresif menurun. Penelitian ini bertujuan untuk mengetahui pengaruh aromaterpi cendana dengan teknik Vaporizer terhadap prilaku agresif dengan metode eksperimen Single Subject Research (SSR) desain A B A. Subjek penelitian ini adalah seorang anak tunagrahita yang memiliki prilaku agresif. Hasil penelitian menunjukkan bahwa aromaterapi cendana berpengaruh terhadap menurunnya frekuensi prilaku agresif. Namun demikian, efek dari intervensi tersebut tidak begitusignifikan setelahpemberian aromaterapi dihentikan.  tunagrahita, agresif, aromaterapi
The Steiner Wiener Index of A Graph
Venue: Discuss. Math. Graph Theory

The Wiener index W(G) of a connected graph G, introduced by Wiener in 1947, is defined as W(G) u,vV(G) d(u, v) where dG(u, v) is the distance between vertices u and v of G. The Steiner distance in a graph, introduced by Chartrand et al. in 1989, is a natural generalization of the concept of classical graph distance. For a connected graph G of order at least 2 and S V (G) the Steiner distance d(S) of the vertices of S is the minimum size of a connected subgraph whose vertex set is S. We now introduce the concept of the Steiner Wiener index of a graph. The Steiner k Wiener index SWk(G) of G is defined by Expressions for SWk for some special graphs are obtained. We also give sharp upper and lower bounds of SWk of a connected graph, and establish some of its properties in the case of trees. An application in chemistry of the Steiner Wiener index is reported in our another paper.
A Survey of approaches for mining large data sets

Data mining environment creates a lot of information, that should be investigated, examples must be removed from that to pick up learning. In this new period with blast of information both organized and unstructured, in the field of genomics, meteorology, science, ecological examination and numerous others, it has gotten to be hard to process, oversee and break down examples utilizing customary databases and architectures. Thus, a legitimate structural engineering ought to be comprehended to pick up information about the Big Data.This paper presents a review of various algorithms from necessary for handling such large data set. These algorithms define various structures and methods implemented to handle Big Data, also in the paper are listed various tool that were developed for analyzing them.