nils-herrmann/clean_scirepeval huggingface dataset:
Abstract 4866: Development and characterization of novel CD40 antibody agonists for cancer immunotherapy

CD40 is a key molecule in the regulation of immune responses and its activity can be modulated using antibodies. In particular, agonist CD40 antibodies are highly effective in preclinical tumor models either through direct interaction with CD40 expressing lymphomas, or indirectly through the activation of an anti tumor immune response. To date, limited clinical data have been reported with strong CD40 agonist antibodies; nonetheless it seems likely that targeting this pathway will require a balance between the benefits of potent immune stimulation to drive antitumor responses, and the harm that can result from non specific immune cell activation. We set out to develop novel human antiCD40 antibodies with different levels of agonist activity to identify a lead candidate for systemic application. Here we describe two novel fully human anti CD40 mAbs with good agonist activity resulting in immune cell activation and direct anti lymphoma activity in a xenograft model.
A New Filter Bank Multicarrier System With Two Prototype Filters for QAM Symbols Transmission and Reception
Venue: IEEE Transactions on Wireless Communications

A filter bank multicarrier quadrature amplitude modulation (FBMC QAM) system with two prototype filters for transmitting QAM symbol is proposed, and the orthogonality conditions for the FBMC QAM system without the intrinsic interference is derived. The proposed transmitter performs the individual filtering for the even and odd numbered sub carrier symbols, respectively. In order to satisfy the derived orthogonality conditions, we perform a sub block wise reverse ordering procedure for the outputs of the odd numbered sub carrier filter. Also, this paper shows that the proposed FBMC QAM system satisfies the suggested orthogonality conditions and can use the multiple input multiple output transmission schemes as the conventional orthogonal frequency division multiplexing (OFDM) systems. The signal to interference power ratio and the bit error rate (BER) for the proposed FBMC QAM system are evaluated. Numerical results show that the proposed FBMC QAM system has almost the same BER performance compared with the FBMC OQAM and OFDM systems.
A novel comprehensive macroscopic model for time dependent vehicle routing problem with multi alternative graph to reduce fuel consumption: A case study
Venue: Comput. Ind. Eng.

Diagram of the emission factor changes.Display Omitted A comprehensive macroscopic model to reduce the fuel consumption is presented.Multi alternative graph for green time dependent routing problem is considered.Several traffic patterns and the 'first in first out' property is considered.A Modified Metaheuristic algorithm based on Gaussian Firefly algorithm is developed.One of the distribution companies in Iran is selected as a case study. Vehicle routing problem (VRP) has attracted the attention of many researchers in recent years, but in spite of its application, researchers have shown little interest in the time dependent vehicle routing problem. In recent years, much attention has been paid to the reduction of environmental emissions and reduction of fuel consumption. In this paper, the factors effective in the fuel consumption in time dependent vehicle routing have been comprehensively studied and by considering factors such as load, vehicle speed, road gradient, and urban traffic, a novel comprehensive macroscopic model is presented to calculate fuel consumption in time dependent vehicle routing problem. Additionally, the multi alternative graph which enjoys great importance in time dependent routing problem is also considered in the model presented. With regard to the issue that proposed problem belongs to the class of NP hard problems, to find suitable routes with the least fuel consumption, an improved algorithm based on Gaussian Firefly algorithm is proposed. The results obtained from the proposed algorithm in comparison to Gaussian and basic Firefly algorithms show the appropriate performance of the suggested algorithm. Ultimately, one of the distribution companies in one of the cities of Iran (Esfahan) is studied as a case study.
Investigating the Physical, Mechanical and Thermal Properties of Common Roofing Materials in Sri Lanka

In Sri Lanka, the most common roofing materials use for residential housings are the clay tiles, asbestos sheets and cement tiles. In this work efforts have been made to test physical and mechanical properties of the existing calicut clay tiles asbestos corrugated sheets and pressed cement tiles according to SLS 2:1975, SLS 9:2001 and SLS 1267:2005 and to find out whether they satisfy the requirements specified in the standard. Thermal conductivity has been measured by Lee's Disk method. According to the test results, the chosen calicut clay tile sample satisfied all the requirements except width and mass whereas width and pitch of corrugation were not satisfied in asbestos corrugated sheets and thickness was not satisfied in cement tiles. Thermal conductivity of clay, asbestos and cement tile was 0.7106 W/mK, 0.4733 W/m.K and 0.5619 W/m.K. It cannot be predicted that which material offers the best indoor thermal comfort only by considering the thermal conductivity value itself of the roofing material.
THD and efficiency improvement in multi level inverters through an open end winding configuration
Venue: 2016 IEEE Energy Conversion Congress and Exposition (ECCE)

A new approach, based on a current controlled Asymmetrical Hybrid Multilevel Inverter (AHMLI) is proposed to reduce power losses and output current distortion on Multi Level Inverters (MLI) used in AC motor drives, STAT COM devices, Photovoltaic and Wind generators. A key feature of the proposed approach is that the AC machine (motor or transformer) is operated in an open end winding configuration, being supplied on one end by a main Multi Level Inverter and, on the other side, by an auxiliary Two Level Inverter (TLI) The MLI controls the main active power stream; it operates at a low switching frequency and can be equipped with very low on state voltage drop IGBT devices. The auxiliary TLI is instead operated according to a conventional high frequency two level PWM technique and acts as an active power filter providing only a null average power to the AC machine. As the DC bus voltage of the TLI is remarkably lower that that of the main MLI, the auxiliary inverter can be equipped with low switching losses IGBTs, or even Power MOS devices. Simulations and experimental results confirm that using the proposed approach, the phase current harmonic content is remarkably reduced, the efficiency is increased and in motor drive applications, the torque ripple is mitigated.
A new high capacity compact power modules for high power EV/HEV inverters
Venue: 2016 IEEE Applied Power Electronics Conference and Exposition (APEC)

This paper presents a new power semiconductor IGBT module family dedicated for Electric Vehicle (EV) and Hybrid Electric Vehicle (HEV) power train inverter applications, especially for higher power requirements. The new IGBT module family adopts a 6 in 1 circuit configuration with an optimized internal layout, Direct Lead Bond (DLB) structure and an integrated Al fin for direct liquid cooling. As a result, this new power module family has simultaneously achieved high performance, low self inductance, small size and light weight. Compared to conventional products with similar power capabilities, the adoption of these innovative technologies has led to a 20% improvement in thermal performance, 30% reduction of self inductance, 50% reduction of the module's footprint, and a 70% reduction of the module's weight.
PERBEDAAN PENGGUNAAN POVIDONE IODINE 1% DENGAN NACL 0,9% SEBAGAI DEKONTAMINASI ORAL TERHADAP KOLONISASI STAPHYLOCOCCUS AUREUS PADA PASIEN POST OPERASI DENGAN GENERAL ANESTHESIA DI RUANG MAWAR RSUD DR. ABDOER RAHEM SITUBONDO

General anesthesia dapat melemahkan otot pernapasan, sehingga menyebabkan akumulasi sekret di orofaring. Kurangnya kebiasaan oral hygiene pada pasien post operasi merupakan salah satu faktor risiko meningkatkan pertumbuhan flora normal, misalnya Staphylococcus aureus. Salah satu intervensi keperawatan untuk mengurangi pertumbuhan kolonisasi Staphylococcus aureus adalah melakukan dekontaminasi oral. Penelitian ini menganalisis perbedaan penggunaan povidone iodine 1% dan NaCl 0, 9% sebagai dekontaminasi oral terhadap kolonisasi Staphylococcus aureus pada pasien post operasi dengan general anesthesia di Ruang Mawar RSUD dr. Abdoer Rahem Situbondo. Desain penelitian menggunakan non equivalent control group dengan consecutive sampling. Sampel sebanyak 20 responden yang dibagi menjadi dua kelompok, 10 responden dalam dua minggu pertama sebagai kelompok perlakuan dengan menggunakan povidone iodine 1% dan 10 responden dalam dua minggu berikutnya sebagai kelompok kontrol dengan menggunakan NaCl 0,9% Analisa data menggunakan uji Mann Whitney U dengan CI 95 Hasil penelitian menunjukkan bahwa povidone iodine 1% lebih efektif daripada NaCl 0, 9% dengan uji Mann Whitney U test (p value 0,044) Tindakan perawat pada pasien post operasi dengan general anesthesia adalah memberikan motivasi dan edukasi tentang pentingnya dekontaminasi oral dengan menggunakan povidone iodine 1%
A circularly polarized planar aperture antenna array at 60 GHz band
Venue: 2016 IEEE International Symposium on Antennas and Propagation (APSURSI)

A new circularly polarized (CP) planar aperture antenna array for cost sensitive, broadband and high gain millimeter wave applications is proposed. The antenna is composed of an aperture patch formation on one substrate layer while a network of substrate integrated waveguide (SIW) is implemented on another layer below that easily feeds the array arrangement through aperture coupling. Circular polarization is achieved by virtue of the diagonal feeding slot and the cross shaped patch whereas the relatively large opening cavity structure making the physical aperture of the radiating element guarantees high gain at the broadside direction. A 2x2 elements array has been designed at 60 GHz band using printed circuit board (PCB) technology, which shows wide axial ratio (AR<;3dB) and impedance >S11< 10dB) bandwidths of 31% and 25% respectively, and high left handed CP (LHCP) gain up to 19 dBic.
An Empirical Study of Skip Gram Features and Regularization for Learning on Sentiment Analysis
Venue: ECIR

The problem of deciding the overall sentiment of a user review is usually treated as a text classification problem. The simplest machine learning setup for text classification uses a unigram bag of words feature representation of documents, and this has been shown to work well for a number of tasks such as spam detection and topic classification. However, the problem of sentiment analysis is more complex and not as easily captured with unigram (single word) features. Bigram and trigram features capture certain local context and short distance negations thus outperforming unigram bag of words features for sentiment analysis. But higher order n gram features are often overly specific and sparse, so they increase model complexity and do not generalize well.
A Deep Relevance Matching Model for Ad hoc Retrieval
Venue: CIKM

In recent years, deep neural networks have led to exciting breakthroughs in speech recognition, computer vision, and natural language processing (NLP) tasks. However, there have been few positive results of deep models on ad hoc retrieval tasks. This is partially due to the fact that many important characteristics of the ad hoc retrieval task have not been well addressed in deep models yet. Typically, the ad hoc retrieval task is formalized as a matching problem between two pieces of text in existing work using deep models, and treated equivalent to many NLP tasks such as paraphrase identification, question answering and automatic conversation. However, we argue that the ad hoc retrieval task is mainly about relevance matching while most NLP matching tasks concern semantic matching, and there are some fundamental differences between these two matching tasks. Successful relevance matching requires proper handling of the exact matching signals, query term importance, and diverse matching requirements. In this paper, we propose a novel deep relevance matching model (DRMM) for ad hoc retrieval. Specifically, our model employs a joint deep architecture at the query term level for relevance matching. By using matching histogram mapping, a feed forward matching network, and a term gating network, we can effectively deal with the three relevance matching factors mentioned above. Experimental results on two representative benchmark collections show that our model can significantly outperform some well known retrieval models as well as state of the art deep matching models.
Strategic Financial Management: Road to sustainability and Corporate efficiency

The capital structure design is a crucial job as it involves a complex tradeoff among several considerations like income, risk, flexibility, control, timing of issue and so on. The dividend policy of a firm determines the proportion of earnings paid to shareholders by way of dividends and the proportion of income ploughed back in the firm for reinvestment purposes. If a firm's capital structure decision making is independent of its dividend payout policy, then a higher dividend payment will entail a greater dependence on external financing. Thus, the dividend policy has a bearing on the choice of financing. The capital structure and dividend payout policy always differ across companies, industries and sectors worldwide. The current study evaluates the impact of capital structure on dividend decisions of select cement companies in India. It was concluded that profitability and risk had significant influence on the capital structure and profitability had influenced the dividend decisions of the Indian cement companies. It was also revealed that there exists a mild correlation between dividend yield ratio and Long term debt to equity ratio and Long term debt to asset ratio.
TALENT MANAGEMENT PRACTICES IN THE INDIAN BANKING SECTOR: A STEP TOWARDS THE GROWTH OF INDIAN ECONOMY

Talent Management within organization is a human resource strategy that seeks to identify, develop, motivate, reward and retain talented and potential employees. Finding and managing talent has become one of the most important and powerful buzzwords in corporate HR and Training today. Now Talent is harder to find and it becomes easier to waste and lose. The organization's ability to consistently seek, attract, utilize and keep talent will provide a source of competitive advantage. Talent contributes a lot to the performance of the organization and its management has a direct impact on the sustainability and growth of the overall business. Talent management is a 'forward looking' function. Talent management improves the organization's flexibility and performance. It also provides the needed information and tools like workforce planning, recruitment, strategic plan and goal alignment, leadership development, recognition programs, diversity and inclusion, retention etc. which ultimately give rise to developing suitable plans for business growth, change, acquisitions, new product and service initiatives. The goal of talent management is to create a high performance sustainable organization that meets its strategic and operational goals and objectives. Further, rewards, recognitions, training, development and performance appraisal are considered as the most effective talent management practices followed by the organizations.
Is mirabegron equally as effective when used as first or second line therapy in women with overactive bladder?
Venue: International Urogynecology Journal

previous studies have investigated the efficacy of mirabegron 50 mg as the first line therapy in OAB patients. Hence, the primary objective of this study was to evaluate the efficacy of mirabegron in treatment naive patients in comparison with those who had discontinued antimuscarinic therapy because of insufficient efficacy.MethodsAll consecutive women who had pure OAB symptoms (including urgency with or without urgency incontinence and frequency) for at least 3 months were considered for this study. Women were divided into two groups: women without any previous pharmacological treatment for OAB (group 1) and women with a previous history of failed antimuscarinics therapy (group 2).ResultsAt 3 month follow up, the objective results on the basis of the frequency volume chart showed a significant improvement in both groups. Furthermore, a significant reduction in the Overactive Bladder Questionnaire Short Form (OABq SF) score and in the Indevus Urgency Severity Scale (IUSS) questionnaire were reported in both groups. However, the improvement in objective and subjective outcomes was superior in group 1 to that in group 2.ConclusionsMirabegron is efficacious in improving OAB symptoms in both naive patients and those who discontinued primary antimuscarinic therapy; however, its efficacy is superior when prescribed as first line therapy.
Dermatophilus congolensis Infection in Platypus (Ornithorhynchus anatinus) Tasmania, Australia, 2015
Venue: Journal of Wildlife Diseases

We report disease due to Dermatophilus congolensis infection in three of 13 (23% platypuses (Ornithorhynchus anatinus) from a catchment in Tasmania, Australia. This pathogen has not previously been reported in platypuses. Two of the three infected platypuses had extensive scab formations, but no substantial hair loss was apparent.
Distribution and characteristics of the platypus (Ornithorhynchus anatinus) in the Murrumbidgee catchment

Little is known of the current status of platypus (Ornithorhynchus anatinus) populations in the Murrumbidgee catchment and other west flowing rivers in the Murray Darling Basin. Platypus distribution in the Murrumbidgee catchment was determined from sightings, reports by government departments, the literature and a capture release study. The platypus was found to be widespread in the catchment, including all subcatchment and elevation categories, but most reports were from the middle and upper subcatchments. Sixty five captures of 55 individual platypuses were made during 61 trap nights to 31 study sites in the Murrumbidgee catchment during 2009 10. Only three juveniles (all females) were captured and recapture rates were low, with only nine platypuses captured more than once. Adult males had body weights of 980 2180 g and body lengths of 42 60 cm (n 32) Adult females weighed 795 1480 g and were 38 52 cm long (n 20) Tail fat index was significantly affected by season and platypus age, while in comparison, season, platypus length and weight had a significant effect on tail volume index. This study established a baseline that provides a starting point from which the impacts of environmental disturbances or diseases occurring over time can be measured and investigated.
Mobile Web Adoption in Top Ranked University Libraries: A Preliminary Study

This paper aims to study the level of adoption of mobile access to the academic libraries in the best universities in the world as well as the quality of services offered in order to ascertain if the quality of academic apps and mobile websites are at the level of the overall web impact of world class universities. For the top 50 universities according to the Ranking Web of Universities (2014) we determined whether there is a mobile website or app for their libraries. Finally we evaluated the services offered against a list of 14 indicators. The results show that 88% of the libraries studied (44) offer mobile access via web or app, showing a high level of mobile adoption in elite universities. The form is clearly uneven: 80% (40) offers mobile web access while only 34% (17) has an app. As to the content, no library offered all 14 points evaluated, and the results are varied. Only 50% of apps meet at least half the indicators. In the case of mobile web this figure improves notably to 74.3% We can note a high level of mobile web adoption in the world's best universities, although the quality does not reach their level of excellence.
Early farmers from across Europe directly descended from Neolithic Aegeans
Venue: Proceedings of the National Academy of Sciences

One of the most enduring and widely debated questions in prehistoric archaeology concerns the origins of Europe's earliest farmers: Were they the descendants of local hunter gatherers, or did they migrate from southwestern Asia, where farming began? We recover genome wide DNA sequences from early farmers on both the European and Asian sides of the Aegean to reveal an unbroken chain of ancestry leading from central and southwestern Europe back to Greece and northwestern Anatolia. Our study provides the coup de grace to the notion that farming spread into and across Europe via the dissemination of ideas but without, or with only a limited, migration of people. Farming and sedentism first appeared in southwestern Asia during the early Holocene and later spread to neighboring regions, including Europe, along multiple dispersal routes. Conspicuous uncertainties remain about the relative roles of migration, cultural diffusion, and admixture with local foragers in the early Neolithization of Europe. Here we present paleogenomic data for five Neolithic individuals from northern Greece and northwestern Turkey spanning the time and region of the earliest spread of farming into Europe. We use a novel approach to recalibrate raw reads and call genotypes from ancient DNA and observe striking genetic similarity both among Aegean early farmers and with those from across Europe. Our study demonstrates a direct genetic link between Mediterranean and Central European early farmers and those of Greece and Anatolia, extending the European Neolithic migratory chain all the way back to southwestern Asia.
PDFFigures 2.0: Mining figures from research papers
Venue: 2016 IEEE/ACM Joint Conference on Digital Libraries (JCDL)

Figures and tables are key sources of information in many scholarly documents. However, current academic search engines do not make use of figures and tables when semantically parsing documents or presenting document summaries to users. To facilitate these applications we develop an algorithm that extracts figures, tables, and captions from documents called "PDFFigures 2.0." Our proposed approach analyzes the structure of individual pages by detecting captions, graphical elements, and chunks of body text, and then locates figures and tables by reasoning about the empty regions within that text. To evaluate our work, we introduce a new dataset of computer science papers, along with ground truth labels for the locations of the figures, tables, and captions within them. Our algorithm achieves impressive results (94% precision at 90% recall) on this dataset surpassing previous state of the art. Further, we show how our framework was used to extract figures from a corpus of over one million papers, and how the resulting extractions were integrated into the user interface of a smart academic search engine, Semantic Scholar (www.semanticscholar.org) Finally, we present results of exploratory data analysis completed on the extracted figures as well as an extension of our method for the task of section title extraction. We release our dataset and code on our project webpage for enabling future research (http:/pdffigures2.allenai.org)