nils-herrmann/clean_scirepeval huggingface dataset:
Comparison of Outcomes of Hematopoietic Cell Transplants from T Replete Haploidentical Donors Using Post Transplantation Cyclophosphamide with 10 of 10 HLA A, B, C, DRB1, and DQB1 Allele Matched Unrelated Donors and HLA Identical Sibling Donors: A Multivariable Analysis Including Disease Risk In
Venue: Biology of blood and marrow transplantation journal of the American Society for Blood and Marrow Transplantation

Outcomes of 475 consecutive patients undergoing first allogeneic transplantation for hematologic malignancy performed using T replete HLA haploidentical donors and post transplantation cyclophosphamide (HIDT; n 116) were compared with contemporaneous patients transplanted from 10 of 10 HLA allele matched unrelated donors (MUDT; n 178) or HLA identical sibling donors (MRDT; n 181) Uniform supportive care measures and assessments were used. Median follow up was 45 months. HIDT patients were more likely than MUDT patients to be black (44% versus 2% P .001) At 2 years after transplantation, estimates of overall survival were 57% for HIDT, 59% for MUDT, and 72% for MRDT (P not significant [NS] for HIDT versus MUDT; P .02 for HIDT versus MRDT) corresponding disease free survival rates were 54% 50% and 56% (P NS for both comparisons) The respective cumulative incidences (CIs) of nonrelapse mortality were 17% 16% 14% and those of relapse were 29% 34% and 30% (P NS for all) The respective CIs of acute graft versus host disease (GVHD) grade II IV were 41% 48% and 28% (P NS for HIDT versus MUDT; P .005 for HIDT versus MRDT) At 2 years, the respective CIs of moderate/severe chronic GVHD were 31% 47% and 44% (P .004 for HIDT versus MUDT; P .032 for HIDT versus MRDT) and 19% of HIDT recipients, 42% of MUDT recipients, and 35% of MRDT recipients were on systemic immunosuppressive treatment (P .007 for HIDT versus MUDT) In recipients of peripheral blood stem cell grafts, the incidence of moderate severe chronic GVHD was significantly lower in HIDT recipients compared with MUDT recipients (2 year CI, 25% versus 48% P .002) In a multivariate analysis incorporating Disease Risk Index and other significant covariates, survival (hazard ratio [HR] 1.31; P .15) and disease free survival (HR, 0.96; P .79) were not significantly different between HIDT and MUDT recipients, but the incidence of chronic GVHD was lower in HIDT recipients (moderate severe, HR, 0.59; P .007) HIDT produced similar long term survival with lower rates of chronic GVHD than optimally matched MUDT. HIDT should be considered a standard of care option for patients lacking a matched sibling donor.
China's Cement Industry Implicit Carbon Dioxide Emissions Research

Cement production is one major anthropogenic carbon dioxide (CO2) emission source. In China, domestic demand saturated situation caused the rapid increase of the cement exports. Western developed countries, in order to prevent leakage of carbon, will apply carbon tariffs to carbon intensive imports from developing countries such as China. Under the pressure of reducing carbon emissions, it is of important significance to study CO2 emissions in cement production process. We adopt the plant level micro data in 2500 t and 5000 t new suspension preheater dry process (NSP) cement production line, and through data analysis, calculated CO2 emissions in each stage of cement production process, conducted environmental appraisal, measured the amount of carbon emissions in domestic cement production and implied carbon emissions in cement for export. As a result, we found a big deviation between CO2 emissions factors based on the direct data and in the previous literatures, and believe that the CO2 emission factor in Chinese cement production may be overstated in previous studies.
Pengenalan rangkakerja metodologi dalam kajian penyelidikan: satu kajian literatur

Kajian penyelidikan merupakan kaedah akademik yang diaplikasikan dalam dunia sebenar bagi menyelesaikan masalah berkaitan dengan masyarakat. Proses penyelidikan dalam mencapai objektif kajian mempunyai rangkakerja lengkap termasuk metodologi. Metodologi ialah kaedah digunakan untuk mengutip dan mengumpul data melalui tatacara efektif bagi menjawab permasalahan kajian. Metodologi dibahagikan kepada tiga peringkat iaitu proses perancangan, proses aplikasi dan proses analisis. Kajian literatur rangkakerja metodologi ini mengutamakan proses perancangan yang melibatkan reka bentuk kajian penyelidikan yang boleh dibahagikan kepada eksperimental dan bukan eksperimental. Kaedah eksperimental boleh dikategorikan kepada kajian eksperimental benar dan kajian kuasi eksperimental. Kaedah bukan eksperimental dibahagikan kepada kajian tinjauan, kajian lapangan, kajian kes, kajian tindakan dan kajian sejarah. Kebanyakan kaedah eksperimental digunakan dalam bidang sains tulen, manakala kaedah bukan eksperimental digunakan dalam bidang sains sosial. Walau bagaimanapun, kedua dua kaedah masih relevan untuk diaplikasikan ke dalam bidang bidang kajian tertentu agar dapat mencapai objektif dan hipotesis kajian. Oleh itu, metodologi wajib dirancang dan diaplikasikan dengan betul, tepat dan jitu supaya proses sebelum dan semasa mengutip data serta selepas mengumpul data tidak mengalami sebarang kesalahan, kesilapan dan kecuaian yang boleh menjejaskan kajian peneyelidikan.
Extensive dataset for oxidative degradation of ethanolamine at 55 75 degC and oxygen concentrations from 6 to 98%

Post combustion CO 2 capture using amines as chemical absorbents is a relatively mature technology. Rate of reaction and desorption energy demand are normally prime criteria for evaluation of new solvents while degradation and corrosion studies are often postponed. However, degradation and corrosion are in many cases showstoppers and should be considered at an early stage. In this work, a systematic study has been conducted on oxidative degradation of 30 wt% ethanolamine (MEA) for oxygen concentrations: 6, 21, 49 and 98% and temperatures: 55, 65 and 75 degC. The formation of ten primary degradation compounds (acids, ammonia and alkyl amines) and seven secondary degradation compounds (HEGly, OZD, HEPO, HEF, HEA, HEI and BHEOX was monitored as function of time over a period of 3 6 weeks. The full comprehensive data set is available in the supplementary information for development of models describing the degradation behavior. Suggested mechanisms for formation of seven secondary degradation compounds; HEGly, HEPO, OZD, HEF, HEA, BHEOX and HEI from literature were compiled and discussed in view of the experimental results to suggest pathways which are more likely than others. The rate of MEA degradation increases with increasing temperature and oxygen concentration. The overall nitrogen balances were closed within 83 97% the higher deviations observed at the highest temperature, 75 degC. HEF, HEI and ammonia were the degradation compounds that most significantly contributed to the nitrogen balance in most experiments. However, at 6% O 2 content, HEGly was the major nitrogen containing degradation compound identified. Formate was found to be the major anionic compound in all experiments. HEGly formation was found to be independent on O 2 partial pressure, but this may not be true for the further reaction of HEGly. The results suggests OZD formation to be oxygen dependent. However, only one mechanism is so far suggested for an oxygen dependent pathway. Both OZD and HEPO concentrations increase with oxygen concentration. Separate laboratory experiments at constant temperature (55 75 degC) do not capture the HEPO formation seen in pilot plant samples indicating that higher temperatures and/or temperature cycles are necessary. The results clearly show that performing accelerated degradation tests with 98% oxygen cannot easily be extrapolated to what happens at 6% oxygen, and therefore may not be representative for the situation in an industrial plant both with regard to rates of formation and products formed.
Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment
Venue: Front. Hum. Neurosci.

Aerobic exercise (AE) has been widely praised for its potential benefits to cognition and overall brain and mental health. In particular, AE has a potent impact on promoting the function of the hippocampus and stimulating neuroplasticity. As the evidence base rapidly builds, and given most of the supporting work can be readily translated from animal models to humans, the potential for AE to be applied as a therapeutic or adjunctive intervention for a range of human conditions appears ever more promising. Notably, many psychiatric and neurological disorders have been associated with hippocampal dysfunction, which may underlie the expression of certain symptoms common to these disorders, including (aspects of) cognitive dysfunction. Augmenting existing treatment approaches using AE based interventions may promote hippocampal function and alleviate cognitive deficits in various psychiatric disorders that currently remain untreated. Incorporating non pharmacological interventions into clinical treatment may also have a number of other benefits to patient well being, such as limiting the risk of adverse side effects. This review incorporates both animal and human literature to comprehensively detail how AE is associated with cognitive enhancements and stimulates a cascade of neuroplastic mechanisms that support improvements in hippocampal functioning. Using the examples of schizophrenia and major depressive disorder, the utility and implementation of an AE intervention to the clinical domain will be proposed, aimed to reduce cognitive deficits in these, and related disorders.
Physical activity and exercise attenuate neuroinflammation in neurological diseases
Venue: Brain Research Bulletin

Major depressive disorder (MDD) schizophrenia (SCH) Alzheimer's disease (AD) and Parkinson's disease (PD) are devastating neurological disorders, which increasingly contribute to global morbidity and mortality. Although the pathogenic mechanisms of these conditions are quite diverse, chronic neuroinflammation is one underlying feature shared by all these diseases. Even though the specific root causes of these diseases remain to be identified, evidence indicates that the observed neuroinflammation is initiated by unique pathological features associated with each specific disease. If the initial acute inflammation is not resolved, a chronic neuroinflammatory state develops and ultimately contributes to disease progression. Chronic neuroinflammation is characterized by adverse and non specific activation of glial cells, which can lead to collateral damage of nearby neurons and other glia. This misdirected neuroinflammatory response is hypothesized to contribute to neuropathology in MDD, SCH, AD, and PD. Physical activity (PA) which is critical for maintenance of whole body and brain health, may also beneficially modify neuroimmune responses. Since PA has neuroimmune modifying properties, and the common underlying feature of MDD, SCH, AD, and PD is chronic neuroinflammation, we hypothesize that PA could minimize brain diseases by modifying glia mediated neuroinflammation. This review highlights current evidence supporting the disease altering potential of PA and exercise through modifications of neuroimmune responses, specifically in MDD, SCH, AD and PD.
Ranking Operational Causes of Bullwhip Effect in Supply Chain Using AHP: Perception of Managers in FMCG Sector

Bullwhip effect (BWE) which refers to the phenomenon wherein the variance in demand orders increases as one moves up the supply chain (SC) has been a source of concern for most of the SC managers as it has serious implications in the SC. Problems can vary from inefficient ordering and inventory policies (IP) to higher total cost of SC with extreme cases of stock out and disruptions in the SC. The literature on this topic suggests various factors which cause BWE and these have further been divided into two broad groups, namely, "operational causes" and "behavioural causes." This study focuses on the operational factors identified through the survey of literature from 1990 to 2013 and suggests 18 factors which contribute to the BWE. Further, from an analysis of literature, based on a number of articles and their citations, and responses from field experts through a questionnaire, a refined list of seven factors has been taken up for the study. These factors have been ranked using the "analytical hierarchy process" (AHP) The ranking is based on pairwise comparisons based on the perception of the SC managers in the manufacturing sector in north India. The article is divided into five sections. The first section deals with the introduction and identification of the BWE. The second section identifies the various factors which cause this effect under the two broad categories, namely, the operational and behavioural factors. The third section discusses AHP and the methodology used in the article to rank the operational factors. The fourth section presents the results in a tabular and graphical form. Order batching (OB) is found to be the biggest contributor of BWE in manufacturing sector in the aforementioned region followed by demand signal processing (DSP) lead time (LT) IP, price fluctuation (PF) lack of trust (LOT) and number of echelons (NOE) The fifth and final section undertakes a discussion and presents guidelines for future research.
Application of bromelain powder produced from pineapple crowns in tenderising beef round cuts

The purpose of this study is to determine the effect of bromelain produced from pineapple crowns on the quality of beef round cuts. The beef was treated with bromelain at the following condition; the pH of beef was 5.6, the immersion temperature was 60oC, the concentration of bromelain solution was 0.17% and the immersion time was 10 minutes. Bromelain decreased the hardness, water holding capacity (WHC) moisture content and a* value of beef. On the other hand, bromelain increased the pH, cooking loss, and L* and b* values of beef. Bromelain treatment to beef cut samples significantly (P <0.05) increased the essential and non essential amino acids content of beef. This indicated that beef treated with bromelain had a desirable effect on the beef quality.
Assessing the effectiveness of information literacy instruction program: Pre and post evaluation case study

Learning is a continuous process and effective learning relates to students' attitudes, feelings and approach towards the subject of learning. To excel in their academic curricula students must acquire, evaluate and use the available information effectively. One of the mandates of today's higher education is to develop a community of students with information literacy (IL) skills while pursuing their education and enable them to further extend it to their future workplace. This paper examines the information literacy competency of post graduate students of pharmaceutical sciences course at Manipal University, Manipal. The present case study, conducted prior to and after an Information Literacy Instruction (ILI) program at the Health Sciences Library of Manipal University, Manipal, assesses different aspects of information competency for utilization of information resources. Data were collected through a survey prior to IL session and through feedback response at the end of the session (after the session) St uctured questionnaires were distributed to all the participants (125) before and after the instruction program. Students' awareness about the library website, availability of types of resources of the library, familiarity with the name of online database in the health sciences field, knowledge about the use of library catalogue, bibliographic databases and open access resources; confidence level related to search skills before and after the ILI and the usefulness of ILI program were assessed during the study. The results indicated that the information literacy instruction had a positive influence on effective learning of information literacy skills.
Communicating Sensory Attributes and Innovation Through Food Product Labeling

This article explores the influence of food product packaging on consumers' sensory expectations and perceived newness of the product. Two experiments examine to what extent consumers use product typicality, graphical representations, and package typicality in evaluating new food products. Study 1 finds that (1) a typical flavor induces more positive expectations of pleasantness, taste, color, and smell, and (2) the presence of graphic representation on product labels increases perceived pleasantness but does not affect sensory expectations. Study 2 indicates that the product seems newer in the absence of a package (label only condition) but when the product packaging is presented, an atypical package conveys more newness than a typical package. These results provide practical guidelines for the design and introduction of innovative food products.
Galaxy M: a Galaxy workflow for processing and analyzing direct infusion and liquid chromatography mass spectrometry based metabolomics data
Venue: GigaScience

BackgroundMetabolomics is increasingly recognized as an invaluable tool in the biological, medical and environmental sciences yet lags behind the methodological maturity of other omics fields. To achieve its full potential, including the integration of multiple omics modalities, the accessibility, standardization and reproducibility of computational metabolomics tools must be improved significantly.ResultsHere we present our end to end mass spectrometry metabolomics workflow in the widely used platform, Galaxy. Named Galaxy M, our workflow has been developed for both direct infusion mass spectrometry (DIMS) and liquid chromatography mass spectrometry (LC MS) metabolomics. The range of tools presented spans from processing of raw data, e.g. peak picking and alignment, through data cleansing, e.g. missing value imputation, to preparation for statistical analysis, e.g. normalization and scaling, and principal components analysis (PCA) with associated statistical evaluation. We demonstrate the ease of using these Galaxy workflows via the analysis of DIMS and LC MS datasets, and provide PCA scores and associated statistics to help other users to ensure that they can accurately repeat the processing and analysis of these two datasets. Galaxy and data are all provided pre installed in a virtual machine (VM) that can be downloaded from the GigaDB repository. Additionally, source code, executables and installation instructions are available from GitHub.ConclusionsThe Galaxy platform has enabled us to produce an easily accessible and reproducible computational metabolomics workflow. More tools could be added by the community to expand its functionality. We recommend that Galaxy M workflow files are included within the supplementary information of publications, enabling metabolomics studies to achieve greater reproducibility.
From Subsonic to Hypersonic Cruise Missiles: Revolution or Evolution in Land Attack Capabilities?

Since the beginning of the 1990s, the advent and success of US "cruise missile diplomacy"1 has resulted in the emergence of cruise missiles as a coercive political tool and a versatile military weapon. During the initial phase of the last two decades, cruise missiles were predominantly deployed by a select group of advanced industrial countries, in particular the United States. However, the last decade had witnessed a new trend with emerging industrial countries showing increased propensity to develop cruise missiles. In addition to the effectiveness in carrying out all weather precision strikes at standoff ranges, the rationale for acquiring cruise missiles is also driven due to the belief in the weapon systems' ability to penetrate air defenses and the affordability in development and
Ask Yourself the Right Question. To Know and Understand the Beauty of Human Diversity It Is the First Design Step: A Design for All Structured and Autopoietic Tool

The authors discuss the characteristics of a possible way of approaching the complexity of Human Diversity for the purpose of design, implementation and communication, within the cultural framework of inclusive and participatory design; a way which they have experimented and tested, during the European development of the theme "Active Aging" with a quite diverse cluster of actors which has been created to represent the abilities necessities aspirations of the elderly and the various parties involved in the construction and management of housing for the elderly. The authors, after years of practice, were also interested in understanding why some actors are not using the vast work produced worldwide in the field in the lasts decades nor are they familiar with it, and focused on building an easy multilevel approach, in which each level bears its own efficacy, in the attempt to engage those who might be interested but, for various reasons, are not on board yet.
Hybrid decision tree and logistic regression classifier for email spam detection
Venue: 2016 8th International Conference on Information Technology and Electrical Engineering (ICITEE)

Email spam is an increasing problem because it disrupting and time consuming for user, since the easy and cheap of sending email. Email Spam filtering can be done with a binary classification with machine learning as classifier. To date, email spam detection still challenging since the email spam still happens a lot and the detection still need improvement. Decision Tree (DT) is one of famous classifier since DT able to handle nominal and numerical attributes and increasing the efficiency of computing. However, DT has a weakness in over sensitivity to the training set and the noise data or instance that can degrade the performance. In this study, we propose hybrid combination Logistic Regression (LR) and DT for email spam detection. LR is used for reduce noisy data or instance before data feed to DT induction. Noisy data reducing is done by LR by filtering correct prediction with certain false negative threshold. In this study, Spambase dataset is used to evaluate the proposed method. From the experiment, the result shows that proposed method yield impressive and promising result with the accuracy is 91.67% It can be concluded that LR able to improve DT performance by reducing noisy data.
Quantum thermodynamics

Quantum thermodynamics is an emerging research field aiming to extend standard thermodynamics and non equilibrium statistical physics to ensembles of sizes well below the thermodynamic limit, in non equilibrium situations and with the full inclusion of quantum effects. Fuelled by experimental advances and the potential of future nanoscale applications, this research effort is pursued by scientists with different backgrounds, including statistical physics, many body theory, mesoscopic physics and quantum information theory, who bring various tools and methods to the field. A multitude of theoretical questions are being addressed ranging from issues of thermalisation of quantum systems and various definitions of 'work' to the efficiency and power of quantum engines. This overview provides a perspective on a selection of these current trends accessible to postgraduate students and researchers alike.