nils-herrmann/clean_scirepeval huggingface dataset:
A randomized controlled trial evaluating resection of the primary breast tumor in women presenting with de novo stage IV breast cancer: Turkish Study (Protocol MF07 01)

The MF07 01 trial is a multicenter phase III randomized trial of treatment naive stage IV BC patients comparing loco regional surgery (LRS) followed by appropriate systemic therapy (ST) vs ST alone.  To compare 3 year survival and loco regional progression (LRP)  At initial diagnosis patients were randomized 1:1 to LRS group or ST group. After consideration of retrospective studies, we hypothesized at 36 months a survival difference between the two groups to be 18% Assuming a 10% drop out rate and with a one sided log rank test with a 95% CI and a 90% power 271 patients needed to be randomized.  274 patients were accrued; 138 in the LRS group and 136 in the ST group. The groups were comparable regarding age, BMI, HER2 neu, tumor type and size, histologic grade, and bone and visceral metastasis (all p 0.05) There were 76 (55% deaths in the LRS group and 101 (74% in the ST group during the median 40 (20 51) months follow up. At 36 months the survival rate was simi.
Chapter 57 Motor Timing and Sequencing in Speech Production: A General Purpose Framework

Speech production can be considered as a sensorimotor behavior that requires precise control and the dynamic interplay of several parallel processing levels. To produce an utterance, the respective information has to be selected, sequenced, and articulated in an adequate, highly time sensitive manner. Moreover, while these incremental processes develop, sensory feedback is integrated into the system. Efficient temporal processing and coordination is therefore mandatory to successful speech production. Temporal processing in the range of milliseconds to seconds, critical to speech production and perception alike, has been suggested to engage dedicated neural mechanisms. Similar to selection and sequencing, these mechanisms rely on the basal ganglia and their associated thalamocortical circuits. On this basis, we discuss and refine anatomical and functional characteristics of a general purpose framework in which dedicated temporal processing establishes a reference that guides the generation of faster and efficient dynamics in speech production.
DNA Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins
Venue: Front. Plant Sci.

The combined availability of whole genome sequences and genome editing tools is set to revolutionize the field of fruit biotechnology by enabling the introduction of targeted genetic changes with unprecedented control and accuracy, both to explore emergent phenotypes and to introduce new functionalities. Although plasmid mediated delivery of genome editing components to plant cells is very efficient, it also presents some drawbacks, such as possible random integration of plasmid sequences in the host genome. Additionally, it may well be intercepted by current process based GMO regulations, complicating the path to commercialization of improved varieties. Here, we explore direct delivery of purified CRISPR/Cas9 ribonucleoproteins (RNPs) to the protoplast of grape cultivar Chardonnay and apple cultivar such as Golden delicious fruit crop plants for efficient targeted mutagenesis. We targeted MLO 7, a susceptible gene in order to increase resistance to powdery mildew in grape cultivar and DIPM 1, DIPM 2, and DIPM 4 in the apple to increase resistance to fire blight disease. Furthermore, efficient protoplast transformation, the molar ratio of Cas9 and sgRNAs were optimized for each grape and apple cultivar. The targeted mutagenesis insertion and deletion rate was analyzed using targeted deep sequencing. Our results demonstrate that direct delivery of CRISPR/Cas9 RNPs to the protoplast system enables targeted gene editing and paves the way to the generation of DNA free genome edited grapevine and apple plants.
Factors Associated with the Anxiety, Subjective Psychological Well Being and Self Esteem of Parents of Blind Children
Venue: PloS one

The objective was to examine the connection of the personal, social and family context, educational variables with the levels of anxiety, subjective psychological well being and self esteem in a sample of 61 parents of blind children. Results suggest that parents present less anxiety when they have only one child, possess a technical degree, receive remuneration for their work, their child's visual impairment is not progressive, their knowledge about their child's disability is appropriate, and their leisure and labour possibilities have not been affected. Their psychological well being is higher when they are married in first nuptials and perceive that their health is good. Their well being is negatively related to reduced leisure, and self esteem is lower when labour possibilities have been affected. In order for these families to achieve a more pleasant life, with greater psychological well being, lower anxiety and higher self esteem, professionals should be aware of the aspects with a negative impact.
Automatic test case generation for programmable logic controller using function block diagram
Venue: 2016 International Conference on Information Communication and Embedded Systems (ICICES)

Programmable logic controller (PLC) is utilized extensively for automation of the electromechanical process. The functionality of the modern PLC is equivalent to desktop computers. Software source code for PLC's is based on graphical data flow of the functional block diagram (FBD) The software development process has multiple phases. More time and cost to be spent in the testing phase. Effective software testing to be producing high quality in PLC. Test cases are part of the software testing process. If PLC test cases are generated using FBD then all the functional requirements reached. The test case has been lodged in design level to be reducing more cost and time in PLC development process. The applicable test cases are created according to the functional requirements and data flow of FBD. It has been proposed to identify the test coverage criteria, valid and invalid path and data flow from FBD. The methodology has to be completely automated to generate test cases from the functional block diagram. This paper has presented our technique with several PLC devices in a smart home system. The generated test cases achieve high test coverage.
The influence of foot posture on dorsiflexion range of motion and postural control in those with chronic ankle instability.
Venue: Clinical biomechanics

To investigate the effect of foot posture on postural control and dorsiflexion range of motion in individuals with chronic ankle instability.  The study employed a cross sectional, single blinded design. Twenty one individuals with self reported chronic ankle instability (male=5; age=23.76(4.18)years; height=169.27(11.46)cm; weight=73.65(13.37)kg; number of past ankle sprains=4.71(4.10) episode of giving way=17.00(18.20) Cumberland Ankle Instability Score=18.24(4.52) Ankle Instability Index=5.86(1.39) participated. The foot posture index was used to categorize subjects into pronated (n=8; Foot Posture Index=7.50(0.93) and neutral (n=13; Foot Posture Index=3.08(1.93) groups. The dependent variables of dorsiflexion ROM and dynamic and static postural control were collected for both groups at a single session.  There were no significant differences in dorsiflexion range of motion between groups (p=0.22) or any of the eyes open time to boundary variables (p>0.13) The pronated group had significantly less dynamic postural control than the neutral group as assessed by the anterior direction of the Star Excursion Balance Test (p<0.04) However, the pronated group had significantly higher time to boundary values than the neutral group for all eyes closed time to boundary variables (p<=0.05) which indicates better eyes closed static postural control.  Foot posture had a significant effect on dynamic postural control and eyes closed static postural control in individuals with chronic ankle instability. These findings suggest that foot posture may influence postural control in those with chronic ankle instability.
Efficient Multi User Computation Offloading for Mobile Edge Cloud Computing
Venue: IEEE/ACM Transactions on Networking

Mobile edge cloud computing is a new paradigm to provide cloud computing capabilities at the edge of pervasive radio access networks in close proximity to mobile users. In this paper, we first study the multi user computation offloading problem for mobile edge cloud computing in a multi channel wireless interference environment. We show that it is NP hard to compute a centralized optimal solution, and hence adopt a game theoretic approach for achieving efficient computation offloading in a distributed manner. We formulate the distributed computation offloading decision making problem among mobile device users as a multi user computation offloading game. We analyze the structural property of the game and show that the game admits a Nash equilibrium and possesses the finite improvement property. We then design a distributed computation offloading algorithm that can achieve a Nash equilibrium, derive the upper bound of the convergence time, and quantify its efficiency ratio over the centralized optimal solutions in terms of two important performance metrics. We further extend our study to the scenario of multi user computation offloading in the multi channel wireless contention environment. Numerical results corroborate that the proposed algorithm can achieve superior computation offloading performance and scale well as the user size increases.
Edge Computing: Vision and Challenges
Venue: IEEE Internet of Things Journal

The proliferation of Internet of Things (IoT) and the success of rich cloud services have pushed the horizon of a new computing paradigm, edge computing, which calls for processing the data at the edge of the network. Edge computing has the potential to address the concerns of response time requirement, battery life constraint, bandwidth cost saving, as well as data safety and privacy. In this paper, we introduce the definition of edge computing, followed by several case studies, ranging from cloud offloading to smart home and city, as well as collaborative edge to materialize the concept of edge computing. Finally, we present several challenges and opportunities in the field of edge computing, and hope this paper will gain attention from the community and inspire more research in this direction.
A comparative study of stemming algorithms for use with the Uzbek language
Venue: 2016 3rd International Conference on Computer and Information Sciences (ICCOINS)

Stemming is one of the pipeline feature of Information Retrieval and commonly used in natural language processing and text mining. The main purpose of a stemming process is to reduce the inflectional or derivational word into its root form. The difficulties on developing stemming algorithm is to identify and remove affixes since each language in the world has unique characteristics and grammatical rules. This paper compares related study on existing stemmers to be used in Uzbek language. We discuss the type of stemming algorithms, an overview of available popular English stemmers and comparison between discussed stemmers as well as their evaluation and analysis of available stemmers on Uzbek language experiment. Based on the comparative study and experiment, we proposal our model of the Uzbek stemmer that enhances some of the features in Lovins stemmer to suit the requirements for the Uzbek language.
Maternal near miss and mortality due to postpartum infection: a cross sectional analysis from Rwanda
Venue: BMC Pregnancy and Childbirth

BackgroundThe objective of this study is to evaluate 'near miss' and mortality in women with postpartum infections.MethodsWe performed a retrospective review of all patients referred to the University Teaching Hospital of Kigali (CHUK) between January 2012 and December 2013. We identified 117 patients with postpartum infections. Demographic data, length of admission, location of referral, initial surgery and subsequent treatment modalities including antibiotic administration and secondary surgery were recorded. The primary outcome of interest was a composite of maternal mortality and "near miss" defined as more than one laparotomy with/without hysterectomy and prolonged hospitalization.ResultsDiagnoses at CHUK were: pelvic peritonitis (56 deep surgical site infection including fasciitis (17 and endometritis (15 The primary procedures performed prior to transfer were: cesarean section (81 septic abortion management (12 and vaginal delivery (7 Antibiotics were initiated prior to transfer in 66 of women. Surgery was required in 73 of patients. Hysterectomies were performed in 22 of patients. Maternal death occurred in 5 of the patient population. The primary outcome of severe maternal morbidity and mortality occurred in 90 patients (77 .ConclusionPeritonitis primarily as a result of cesarean deliveries is associated with significant morbidity and mortality in our population.
Marxism and Social Movements

Marxism and Social Movements: An Introduction, Colin Barker, Laurence Cox, John Krinsky and Alf Gunvald Nilsen PART 1: THEORETICAL FRAMEWORKS Marxism and Social Movements 1. Class Struggle and Social Movements, Colin Barker 2. What Would a Marxist Theory of Social Movements Look Like? Alf Gunvald Nilsen and Laurence Cox Social Movements Studies and its Discontents 3. The Strange Disappearance of Capitalism from Social Movement Studies, Gabriel Hetland and Jeff Goodwin 4. Marxism and the Politics of Possibility: Beyond Academic Boundaries, John Krinsky PART 2: HOW SOCIAL MOVEMENTS WORK Developmental Perspectives on Social Movements 1. Eppur Si Muove: Thinking 'The Social Movement' Laurence Cox 2. Class Formation and the Labour Movement in Revolutionary China, Marc Blecher 3. Contesting the Postcolonial Development Project: A Marxist Perspective on Popular Resistance in the Narmada Valley, Alf Gunvald Nilsen The Politics of Social Movements 4. The Marxist Rank And File/Bureaucracy Analysis of Trade Unionism: Some Implications for the Study of Social Movement Organisations, Ralph Darlington 5. Defending Place, Remaking Space: Social Movements in Oaxaca and Chiapas, Chris Hesketh 6. Uneven and Combined Marxism within South Africa's Urban Social Movements, Patrick Bond, Ashwin Desai and Trevor Ngwane PART 3: SEEING THE BIGGER PICTURE Comparative Historical Perspective 1. Thinking About (New) Social Movements: Some Insights from the British Marxist Historians, Paul Blackledge 2. Right Wing Social Movements: The Political Indeterminacy Of Mass Mobilisation, Neil Davidson 3. Class, Caste, Colonial Rule, And Resistance: The Revolt of 1857 In India, Hira Singh 4. The Black International as Social Movement Wave: C.L.R. James's History of Pan African Revolt, Christian Hogsbjerg Social Movements against Neoliberalism 5. Language, Marxism and the Grasping of Policy Agendas: Neoliberalism and Political Voice in Scotland's Poorest Communities, Chik Collins 6. Organic Intellectuals in the Australian Global Justice Movement: The Weight of 9/11, Elizabeth Humphrys 7. 'Disorganisation' as Social Movement Tactic: Reappropriating Politics During the Crisis of Neoliberal Capitalism, Heike Schaumberg 8. 'Unity of The Diverse' Working Class Formations and Popular Uprisings From Cochabamba to Cairo, David McNally References
Marxism in the Anthropocene: Dialectical Rifts on the Left

Natural scientists have pointed to the Anthropocene as a new geological epoch, with the precise dating not yet decided, but often traced to the Great Acceleration of the human impact on the environment since 1945. Thus understood, the Anthropocene largely coincides with the rise of the modern environmental movement and corresponds to the age of planetary crisis. This paper looks at the evolution of Marxian and left contributions to environmental thought during this period. Although Marx's ecological materialism is now widely recognized, with the rediscovery of his theory of metabolic rift, the debate has recently shifted to ecological dialectics, including dualism, monism, totality, and mediation, generating a conflict between ecological Marxism and radical ecological monism. It is argued here that only an ecological Marxism, rooted in a materialist dialectic of nature and society, is able to engage effectively with the Great Climacteric that increasingly governs our times.
The Efficacy of Credit Insurance A Study of the Quantitative Impact on Trade Receivables and Receivables Turnover Ratio

Export Trade Credit Insurance is a financial service product that intends to cater to the risk management needs of a company. Its primary purpose is protecting a policy holding company against payment defaults, insolvencies and bankruptcies that their business partners (buyers) can face. This helps the company keep their Accounts/Trades Receivable and bad debt under check. The goal of this thesis is to study the impact of Credit Insurance coverage on a policy holding company's A/R levels, RT Ratio and overall financial health. The sample in the empirical section consists of 7 Finnish companies that were covered by EH Finland from 2012 till 2014, at least. Financial Statements of these 7 Finnish companies, covered by Euler Hermes, Finland have been analyzed. To understand the relative impact of Credit Insurance on these companies, they were compared with industry average values that correspond to a given company's industry type. To help the calculations reflect a fair assessment of this impact, RT ratio has been used to account for the changes in turnover relative to the change in A/R for a given period. The average difference in RT Ratios for these 7 companies between 2 time periods before insurance coverage and under insurance coverage was 4.25 Without 2 outlier sample subjects, the effect increases to 6.41 Notably, the average difference between the RT Ratio for the 7 companies was 0.24 whereas the industries they belonged to saw a reduction in their average by 4.38 Credit Insurance coverage could not make a quantifiable, and more importantly, significant difference on their policy holders' RT Ratio.
The Impact of Working Capital Components Turnover Period Towards Market Value Ratio

Through efficient management of working capital components (cash, accounts receivable, inventory, and accounts payable) companies can increase the value of the company. The purpose of this study is to determine the impact of working capital components turnover period towards the price to book value PBV This study uses 42 samples from 14 companies within three periods. The variables of this study is the PBV as the dependent variable and as the independent variables are cash turnover period accounts receivable turnover period inventory turnover period and accounts payable turnover period. To analyze the phenomena, the multiple linear regression is used to examine the effect of independent variables on the dependent variable The results of the study indicate that the turnover period of cash, accounts receivable and accounts payable have significant effect to PBV, while inventory turnover period does not have significant effect to PBV.  Price to book value (PBV) cash turnover period account s receivable turnover period inventory turnover period account s payable turnover period
A Double Edged Sword? Predicting Consumers' Attitudes Toward and Sharing Intention of Native Advertising on Social Media

Despite the increasing popularity and advantage of native advertising on social media, advertisers are concerned about the possibility of native ads misleading consumers, resulting in boomerang effects. This study attempts to address this concern by comparing the predictive role of native ad nonintrusiveness with that of native ad manipulativeness in consumers' attitude toward and sharing intention of native advertising. Findings from an online survey of 550 U.S. adult consumers showed that native ad nonintrusiveness was positively related to attitude toward and sharing intention of native advertising, whereas native ad manipulativeness was not. Consumers' ad skepticism and persuasion knowledge were negatively related to attitude toward and sharing intention of native advertising; but persuasion knowledge became nonsignificant when native ad nonintrusiveness and manipulativeness were included in regression models. Additionally, those with stronger information seeking motivation showed more positive attitudinal and behavioral responses. This study advances the knowledge of native advertising by examining the possibility of its being a double edged sword. Theoretical and practical implications are discussed.
Predicting user response to sponsored advertising on social media via the technology acceptance model
Venue: Comput. Hum. Behav.

Sponsored advertising has generated strong advertising revenues for Facebook in recent years. As sponsored ads are built on an interactive platform that could be seen as invasive to user privacy, the growth of this advertising platform has important implications for consumers, and advertisers alike. As little research is available on consumer response to sponsored advertising as an interactive technology innovation, the current study assesses the effects of user perceptions of privacy risk, intrusiveness concerns and utilities of sponsored advertising on consumer attitudes and purchase intent. Testing a model derived form the technology acceptance model (TAM) the study found that privacy and intrusiveness concerns are both valid antecedent variables to perceived usefulness but not perceived ease of use of sponsored advertising. While both antecedent variables also influence consumer attitudes toward sponsored advertising, only privacy concerns have an impact product purchase intentions. The hypothesized relations between perceived usefulness, ease of use, attitudes and purchase intentions were also validated.
Elevated Preoperative Serum Gamma glutamyltranspeptidase Predicts Poor Prognosis for Hepatocellular Carcinoma after Liver Transplantation
Venue: Scientific reports

Gamma glutamyltransferase (g GGT) is a membrane bound enzyme that is involved in biotransformation, nucleic acid metabolism, and tumourigenesis. Elevated serum g GGT levels are related to an increased cancer risk and worse prognosis in many cancers. In the present study, we evaluated the prognostic value of preoperative serum g GGT in patients with hepatocellular carcinoma (HCC) who underwent liver transplantation (LT) A total of 130 HCC patients after LT were included in the study. The optimal cut off value of g GGT was 128U/L by receiver operating characteristic analysis, with a sensitivity and specificity of 60.0% and 72.9% respectively. Elevated preoperative serum g GGT was significantly associated with high alpha fetoprotein (AFP) large tumor size, and macro and micro vascular invasion. The 1 3 5 year disease free survival (DFS) and overall survival (OS) rates of HCC patients in the g GGT 128U/L group were poorer than those in the g GGT 128U/L group. Stratification analysis revealed that g GGT exhibited a greater predictive value for DFS and OS in HCC patients beyond the Milan criteria and no macro vascular invasion. In conclusion, elevated preoperative serum g GGT was significantly associated with advanced tumor stage and aggressive tumor behaviors, and serum g GGT can be considered as a prognostic factor for HCC patients after LT, especially for patients beyond the Milan criteria or without macro vascular invasion.