nils-herrmann/clean_scirepeval huggingface dataset:
Team Boundary Spanning through Enterprise Social Media: Exploring the Effects of Group Level Diversity Using a Data Science Approach
Venue: 2016 49th Hawaii International Conference on System Sciences (HICSS)

Effective work groups engage in team boundary spanning, that is, the use of communication ties as conduits to critical external resources. With the proliferation of social media technologies in enterprise settings and the associated increase in visibility of communication ties, understanding their impact on boundary spanning becomes imperative to improving cross boundary knowledge creation and management inside organizations. In this paper, drawing on log data from 415 unique work groups in an enterprise social media (ESM) system, we use a machine learning approach to automatically detect three distinct team boundary spanning activities. Using zero inflated poisson regressions, we further show the effect of group visibility as well as three distinct sources of group structural diversity geographic, functional, and hierarchical on the extent to which teams engage in boundary spanning through ESM. Implications for theory and practice around the use of data science approaches as well as visibility and diversity constructs for understanding team boundary spanning are discussed.
The Structure and Substance of Teachers' Opportunities to Learn about Teacher Evaluation Reform: Promise or Pitfall for Equity?

Despite growing momentum to overhaul teacher evaluation policies and practices, scant research examines how educators at the street level of such reform principals and teachers make sense of them, and almost no research examines the implications of current evaluation reforms for equity. This article provides findings based on a study of 14 districts implementing a new teacher evaluation policy in Connecticut. It focuses on how principals shaped teachers' opportunities to learn about the new policy. We find that the majority of teachers' opportunities to learn were formal and in whole group or one on one formats. We find important differences in the quantity and quality of learning opportunities at the district level, with districts serving greater shares of low income students, students of color, and English language learners generally offering teachers fewer and lower quality opportunities to learn about the new reform than their counterparts. As such, this article builds on prior research illustrating the potential of new evaluation systems to exacerbate inequities and raises important cautions regarding the extent to which the unprecedented teacher evaluation reforms (currently underway) may exacerbate inequities among school districts.
INTERNAL DETERMINANTS OF PROFITABILITY OF COMMERCIAL BANKS IN GHANA

This study investigated internal determinants of commercial banks' profitability in Ghana. A mixed approach (primary and secondary methods) was used in collecting data from (16) commercial banks via purposive sampling approach out from a total of 26. Primary data was obtained through interviews and questionnaires administered to the respondents whiles secondary data was obtained from published materials particularly from the annual financial reports of the selected commercial banks. The study revealed that capital adequacy, credit risk, deposit, Liquidity, Loans and advances, expenses management, efficiency and productivity, bank size, and non interest income management (bank specific variables) are the key internal determinants of commercial banks. Through regression analysis on the effect of the identified determinants based on return on asset (ROA) and net interest margin (NIM) it becomes clear that profitability is influenced by the identified determinants. Specifically, ROA as a measure of banks profitability indicated that all the bank specific variables were found to be significant in determining profitability. The results revealed that well capitalized banks are more profitable as capital adequacy had a positive and significant impact on bank profitability. The results also indicate that there is a positive relationship between liquidity and profitability implying that the more liquid a bank is the more profitable it becomes. Concerning asset quality and bank profitability, asset quality measured in terms of the ratio of provision for bad debt to advances has a significant negative impact on bank profitability. This implies that as the asset quality deteriorates (i.e. credit risk increases) the profitability of the bank also decreases. The study also found a significant negative relationship between operating expense and bank profitability implying that banks are not efficiently managing their expenses. The findings of the study also suggest that large banks tend to enjoy economies of scale as size is positively related to bank profitability. Similarly, when profitability was measured with NIM, the effects of the identified variables were not very much different from the results of the model with ROA. The only difference was in terms of the capital adequacy variable. Surprisingly this variable was negatively related to profitability contrary to the case of ROA where capital adequacy was impacting positively on profitability. Based on the findings of the study, it will be advantageous for policy makers to establish steps that would encourage revenue diversification, reduce operational costs, minimize credit risk and encourage banks to minimize their liquidity holdings.
Phytochemistry and Pharmacology of Anamirta cocculus Willd

Anamirta cocculus is a woody climber of Menispermaceae family remains popular folk remedy in Asia and adjacent regions. It crude drug is officially listed in many Pharmacopoeias. The fruits, especially the seed contain picrotoxin, a very strong poison that was toxic to all vertebrates affecting the CNS, stimulating the respiratory and vagus centres in the medulla and acting on the heart and lungs with diminished pulse. The toxicity results in vomiting, purging, profuse sweating, dimness of vision, unconsciousness and clonic convulsions. Death occurs rapidly due to respiration failure, or slowly from gastro intestinal symptoms, particularly the medulla oblongata and respiratory centre. In South East Asia the fruit of Anamirta cocculus is used mainly as a fish poison and as an insecticide. The plant was large stemmed and, stem and roots contains quaternary alkaloids, such as beriberine, palmatine, magnoflorine, columbamine, oxypalmine, stepharine and the major tertiary alkaloid as 18 oxotetrahydropalmatine. The alkaloids of Anamirta cocculus have antibacterial, antimicrobial, sympatholytical (acetylcholine) and antifertility activities and the isolated alkaloids were confirmed and characterized by UVspectrophotometry, Mass spectroscopy, H1 NMR and C13 NMR spectroscopy.
Chronic low dose rate ionising radiation affects the hippocampal phosphoproteome in the ApoE Alzheimer's mouse model
Venue: Oncotarget

Accruing data indicate that radiation induced consequences resemble pathologies of neurodegenerative diseases such as Alzheimer's. The aim of this study was to elucidate the effect on hippocampus of chronic low dose rate radiation exposure (1 mGy/day or 20 mGy/day) given over 300 days with cumulative doses of 0.3 Gy and 6.0 Gy, respectively. ApoE deficient mutant C57Bl/6 mouse was used as an Alzheimer's model. Using mass spectrometry, a marked alteration in the phosphoproteome was found at both dose rates. The radiation induced changes in the phosphoproteome were associated with the control of synaptic plasticity, calcium dependent signalling and brain metabolism. An inhibition of CREB signalling was found at both dose rates whereas Rac1 Cofilin signalling was found activated only at the lower dose rate. Similarly, the reduction in the number of activated microglia in the molecular layer of hippocampus that paralleled with reduced levels of TNFa expression and lipid peroxidation was significant only at the lower dose rate. Adult neurogenesis, investigated by Ki67, GFAP and NeuN staining, and cell death (activated caspase 3) were not influenced at any dose or dose rate. This study shows that several molecular targets induced by chronic low dose rate radiation overlap with those of Alzheimer's pathology. It may suggest that ionising radiation functions as a contributing risk factor to this neurodegenerative disease.
A matrix free approach to efficient affine linear image registration on CPU and GPU
Venue: Journal of Real Time Image Processing

This paper presents a generic approach to highly efficient image registration in two and three dimensions. Both monomodal and multimodal registration problems are considered. We focus on the important class of affine linear transformations in a derivative based optimization framework. Our main contribution is an explicit formulation of the objective function gradient and Hessian approximation that allows for very efficient, parallel derivative calculation with virtually no memory requirements. The flexible parallelism of our concept allows for direct implementation on various hardware platforms. Derivative calculations are fully matrix free and operate directly on the input data, thereby reducing the auxiliary space requirements from \mathcal {O}(n)$O(n) to \mathcal {O}(1)$O(1) The proposed approach is implemented on multicore CPU and GPU. Our GPU code outperforms a conventional matrix based CPU implementation by more than two orders of magnitude, thus enabling usage in real time scenarios. The computational properties of our approach are extensively evaluated, thereby demonstrating the performance gain for a variety of real life medical applications.
Broadening of cohesinopathies: exome sequencing identifies mutations in ANKRD11 in two patients with Cornelia de Lange overlapping phenotype
Venue: Clinical genetics

Cornelia de Lange syndrome (CdLS) and KBG syndrome are two distinct developmental pathologies sharing common features such as intellectual disability, psychomotor delay, and some craniofacial and limb abnormalities. Mutations in one of the five genes NIPBL, SMC1A, SMC3, HDAC8 or RAD21, were identified in at least 70% of the patients with CdLS. Consequently, additional causative genes, either unknown or responsible of partially merging entities, possibly account for the remaining 30% of the patients. In contrast, KBG has only been associated with mutations in ANKRD11. By exome sequencing we could identify heterozygous loss of function mutations in ANKRD11 in two patients with the clinical diagnosis of CdLS. Both patients show features reminiscent of CdLS such as characteristic facies as well as a small head circumference which is not described for KBG syndrome. Patient A, who carries the mutation in a mosaic state, is a 4 year old girl with features reminiscent of CdLS. Patient B, a 15 year old boy, shows a complex phenotype which resembled CdLS during infancy, but has developed to a more KBG overlapping phenotype during childhood. These findings point out the importance of screening ANKRD11 in young CdLS patients who were found to be negative for mutations in the five known CdLS genes.
Recognition of the Cornelia de Lange syndrome phenotype with facial dysmorphology novel analysis
Venue: Clinical genetics

Facial analysis systems are becoming available to healthcare providers to aid in the recognition of dysmorphic phenotypes associated with a multitude of genetic syndromes. These technologies automatically detect facial points and extract various measurements from images to recognize dysmorphic features and evaluate similarities to known facial patterns (gestalts) To evaluate such systems' usefulness for supporting the clinical practice of healthcare professionals, the recognition accuracy of the Cornelia de Lange syndrome (CdLS) phenotype was examined with FDNA's automated facial dysmorphology novel analysis (FDNA) technology. In the first experiment, 2D facial images of CdLS patients with either an NIPBL or SMC1A gene mutation as well as non CdLS patients which were assessed by dysmorphologists in a previous study were evaluated by the FDNA technology; the average detection rate of experts was 77% while the system's detection rate was 87% In the second study, when a new set of NIPBL, SMC1A and non CdLS patient photos was evaluated, the detection rate increased to 94% The results from both studies indicated that the system's detection rate was comparable to that of dysmorphology experts. Therefore, utilizing such technologies may be a useful tool in a clinical setting.
MDE4IoT: Supporting the Internet of Things with Model Driven Engineering
Venue: IDC

The Internet of Things (IoT) unleashes great opportunities to improve our way of living and working through a seamless and highly dynamic cooperation among heterogeneous things including both computer based systems and physical objects. However, properly dealing with the design, development, deployment and runtime management of IoT applications means to provide solutions for a multitude of challenges related to intelligent distributed systems within the IoT. In this paper we propose Model Driven Engineering (MDE) as a keyenabler for applications running on intelligent distributed IoT systems. MDE helps in tackling challenges and supporting the lifecycle of such systems. Specifically, we introduce MDE4IoT, an MDE approach enabling the modelling of things and supporting intelligence as self adaptation of Emergent Configurations in the IoT. Moreover, we show how MDE, and in particular MDE4IoT, can help in tackling several challenges by providing the Smart Street Lights concrete case.
MDE 4 IoT Supporting the Internet of Things with Model Driven Engineering

The Internet of Things (IoT) unleashes great opportunities to improve our way of living and working through a seamless and highly dynamic cooperation among heterogeneous Things including both computer based systems and physical objects. However, properly dealing with the design, development, deployment and runtime management of this breathing network of Things means to provide solutions for a multitude of challenges. Among them, we focus on: supporting complexity and heterogeneity management, supporting collaborative development, maximising reusability of design artefacts, and providing self adaptation of IoT systems. In this paper we propose Model Driven Engineering (MDE) as a key enabler for solving these challenges and supporting the lifecycle of IoT systems, from their design to runtime management. More specifically, we: (i) introduce MDE4IoT, a Model Driven Engineering Framework supporting the modelling of Things and self adaptation of Emergent Configurations of connected systems in the IoT; and (ii) show how MDE in general, and MDE4IoT in particular, can help in tackling the above mentioned challenges by providing the Smart Street Lights case that we use throughout the paper as concrete case.
Effect of One Unit Blood Donation on Appetite Related Biomarkers.
Venue: Clinical and investigative medicine. Medecine clinique et experimentale

It is commonly reported that blood donation (BD) leads to an increase in appetite. To investigate this claim, a questionnaire was offered to 306 people who had a history of BD at least once in their life. Following a positive outcome from the questionnaire, we further investigated the impact of BD on appetite.  The questionnaire study consists of a 5 question survey with VAS was performed on 399 volunteers. Later, 108 volunteers were enrolled in a laboratory study. Blood samples were withdrawn before and after BD. Leptin, ghrelin, neuropeptide Y (NPY) and alpha melanocyte stimulating hormone (a MSH) levels were measured by ELISA kits. VAS assessment was also performed on all participants before and after BD.  There was a significant decrease in the level of leptin but the levels of ghrelin, NPY and a MSH were unchanged. A significant change in VAS value in terms of appetite was also observed.  The elevation of appetite after BD is predominantly psychological. Hormonal changes may contribute to the control of hypothalamic hunger and satiety centers.
Kutjamarcoot brevirostrum gen. et sp. nov. a new short snouted, early Miocene bandicoot (Marsupialia: Peramelemorphia) from the Kutjamarpu Local Fauna (Wipajiri Formation) in South Australia

Chamberlain, P.M. Travouillon, K.J. Archer, M. Hand, S.J. November 2015. Kutjamarcoot brevirostrum gen. et sp. nov. a new short snouted, early Miocene bandicoot (Marsupialia: Peramelemorphia) from the Kutjamarpu Local Fauna (Wipajiri Formation) in South Australia. Alcheringa 40, XX XX. ISSN 0311 5518. A new bandicoot species, Kutjamarcoot brevirostrum gen. et sp. nov. (Peramelemorphia) is described here from the Leaf Locality, Kutjamarpu Local Fauna (LF) Wipajiri Formation (South Australia) The age of the fossil deposit is interpreted as early Miocene on the basis of biocorrelation between multiple species in the Kutjamarpu LF and local faunas from the Riversleigh World Heritage Area (WHA) Kutjamarcoot brevirostrum is represented by isolated teeth and three partial dentaries and appears to have been short snouted with an estimated mass of 920 g. Phylogenetic analyses place K. brevirostrum in a clade with extant Australian bandicoots and the extinct Madju, but potentially exclude the extant New Guinean bandicoots. Morphometric analysis infers close similarity between K. brevirostrum and species of Galadi in both size and rostral length. They, thus, potentially occupied compatible ecological niches with competitive exclusion perhaps explaining geographical segregation between these broadly coeval lineages. Philippa M. Chamberlain [philippa.chamberlain@uq.net.au] School of Earth Sciences, University of Queensland, St Lucia, Queensland 4072, Australia;  kennytravouillon@hotmail.com] Western Australian Museum, Locked Bag 49, Welshpool DC, WA, 6986, and School of Earth Sciences, University of Queensland, St Lucia, Queensland, 4072, Australia; Michael Archer [m.archer@unsw.edu.au] and Suzanne J. Hand [s.hand@unsw.edu.au] School of Biological, Earth and Environmental Sciences, University of New South Wales, New South Wales, 2052,
New specimens of ektopodontids (Marsupialia: Ektopodontidae) from South Australia

Pledge, N.S. 2016. New specimens of ektopodontids (Marsupialia: Ektopodontidae) from South Australia. Memoirs of Museum Victoria 74: 173 187. Knowledge about the extinct phalangeroid family Ektopodontidae is increased by the discovery of new material from several localities. Previously unknown teeth of Chunia illuminata and Ektopodon stirtoni are described respectively from White Sands Basin and Mammalon Hill, Lake Palankarinna, Lake Eyre Basin, South Australia, with M1 being recorded for the first time for any species of Chunia. and a full maxilla of Ektopodon stirtoni showing the positional relationship between P3 and M1 for the first time; this is even more extreme than the arrangement postulated previously. Another species Ektopodon litolophus has been described on the basis of an M1 found at the Leaf Locality, Lake Ngapakaldi, Lake Eyre Basin. Material from Lake Tarkarooloo, referred to Ektopodon stirtoni, is redescribed as a new species Ektopodon tommosi. Comparisons of M1 of Chunia and Ektopodon species now allow evolutionary trends, such as increasing number of cusps on the molar lophs, and simplification of the cusps, to be discerned.
Description of new cranial material of Propalorchestes (Marsupialia: Palorchestidae) from the middle Miocene camfield beds, Northern Territory, Australia

(c) MUSEUM VICTORIA. Additional material referable to Propalorchestes novaculacephalus from the middle Miocene Camfield Beds is described. A cranium prepared in 1999 2000 from material collected on the T. H. Rich expedition of 1981 represents the most complete skull of the genus found to date. The detailed preservation of the previously unknown rostral anatomy supports the hypothesis that Propalorchestes possessed retracted nasal morphology. Cheek teeth from the skull and an additional isolated mandibular fragment from the same site, adds to the dental record for the genus. It further supports the intermediate condition of the molar morphology between the fully bilophodont Palorchestes and the subselenodont/semilophodont wynyardiid morphologies. The highly retracted nasal morphology and corresponding mandibular features demonstrate an advanced and highly derived condition in contrast to the plesiomorphic features previously described for the basicranium. In comparison to the generalized rostral anatomy of the sister group, the early to middle Miocene Diprotodontidae, this more complete record of Propalorchestes cranial morpholgy, suggests a significantly earlier origin for the highly derived facial anatomy in the Palorchestidae.
Dental anomalies in Didelphis albiventris (Mammalia, Marsupialia, Didelphidae) from Argentina, Brazil and Uruguay

Dental anomalies have been investigated and reported for most orders of mammals, including marsupials. Previous works in Didelphis albiventris Lund, 1840 only described one kind of malformation or just a few observations from some collections, thus the type and presence of anomalies for this species was underestimated. The aim of this contribution is to describe and analyze several dental anomalies found in specimens of Didelphis albiventris from Argentina, Uruguay and Brazil. Dental anomalies were classified in three categories: supernumerary or missing teeth, morphological anomalies in size and shape, and teeth in unusual positions. We found 32 individuals of D. albiventris with anomalies out of 393 analyzed specimens (8.14% some specimens with more than one anomaly. A similar proportion of specimens from Argentina and Uruguay presented anomalies, while in specimens from Brazil anomalies were less common. Anomalies were more commonly found in the upper toothrow and in molars, being supernumerary teeth and molars with unusual crown shape the most common ones. The percentage of specimens with anomalies found for D. albiventris is higher than previously reported for the species, and other Didelphimorphia. Inbreeding and limited gene flow do not appear as possible explanations for the elevated percentage of anomalies, especially due to the ecological characteristics of Didelphis albiventris. Developmental instability and fluctuating asymmetry could be some of the causes for the anomalies found in this species, mostly since the habitat used by D. albiventris tends to be unstable and disturbed. Dental anomalies were mostly found in areas of the toothrow where occlusion is relaxed or does not prevent teeth from interlocking during mastication, and consequently have no functional value.
WARENDJA WAKEFIELD 1 A NEW GENUS OF WOMBAT MARSUPIALIA VOMBATIDAE FROM PLEISTOCENE SEDIMENTS IN McEACHERNS CAVE WESTERN VICTORIA

Two mandibles and six isolated teeth recovered from Pleistocene sediments in McEacherns Cave, western Victoria, represent a new genus and species of a morphologically primitive wombat. It combines unrooted, slightly bilobed molars showing little curvature, with a slender ramus, unlused symphysis, weak development of the masseteric and pterygoid fossae, a low set articular condyle, and a broad coronoid process. The associated faunal assemblage includes typical later Pleistocene taxa, such as Zvgomaturus triiobus, Sthenurus pilli, S. ef. occidentalis and Thylacoleo carnifex, Modern taxa, dominated by Rattus fuscipes, Antechinus stuartii and Perameles nasuta, indicate wet sclerophyll forest