nils-herrmann/clean_scirepeval huggingface dataset:
High Stress and Negative Health Behaviors: A Five Year Wellness Center Member Cohort Study
Venue: Journal of occupational and environmental medicine

The aim of this study was to examine the association between having a high stress level and health behaviors in employees of an academic medical center.  Beginning January 1, 2009, through December 31, 2013, an annual survey was completed by 676 worksite wellness members.  Each year, about one sixth of members had a high stress level, high stress individuals visited the wellness center less often, and most years there was a significant relationship (P 0.05) between stress level and poor physical health behaviors (physical activity level and confidence, strength, climbing stairs) low mental health (quality of life, support, spiritual well being and fatigue) poor nutritional habits (habits and confidence) and lower perceived overall health.  High stress is associated with negative health behavior, and future studies, therefore, should explore strategies to effectively engage high stress employees into comprehensive wellness programs.
Cancer Screening Among Peer Led Community Wellness Center Enrollees.
Venue: Journal of psychosocial nursing and mental health services

Growing evidence suggests health disparities exist in services for individuals with mental disorders served by the public mental health system. The current study assessed the use of cancer screening services among New Jersey residents in publicly funded mental health programs. Self administered written surveys were completed by 148 adults using peer led community wellness centers throughout New Jersey. Information was collected on (a) the use of breast, cervical, and colorectal cancer screening services; (b) barriers to receiving preventive services; and (c) perceptions of overall health. More males than females participated in the study, with equal participation among White and African American individuals. Schizophrenia spectrum disorders were the most common self reported psychiatric condition. Colorectal cancers had lower screening levels compared to those of the general population. Physicians not advising patients to complete tests emerged as a main cause of low screening rates. Wellness initiatives designed by peers collaborating with health care providers may improve adherence to preventive cancer screening measures.
The importance of MDR1 gene polymorphisms for tacrolimus dosage.
Venue: European journal of pharmaceutical sciences official journal of the European Federation for Pharmaceutical Sciences

Polymorphisms of the multi drug resistance (MDR1) gene cause variability in P glycoprotein mediated metabolism of tacrolimus. The aim of this study was to examine the relationship between MDR1 gene single nucleotide polymorphisms (SNPs) and their haplotypes with dosage of tacrolimus in kidney transplant recipients who were cytochrome (CYP) 3A5*3 homozygotes. This study included 91 kidney transplant recipients followed two years after transplantation. Detection and analysis of MDR1 gene polymorphisms in positions C1236T, G2677T/A and C3435T were performed using PCR method. Patients with variant alleles for SNPs G2677T/A and C3435T required higher doses of tacrolimus and had a lower level/dose (L/D) ratio than patients with wild alleles or heterozygotes. That difference was the most obvious for SNP G2677T/A where TT homozygotes required significantly higher doses of tacrolimus during whole follow up. Their L/D was significantly lower in the first month after transplantation. Recipients with CTT/TTT haplotype also had lower L/D than those with CGC/TTT and CGC/CGC, significantly in the 10th and 20th days after transplantation respectively (p<0.05) Our results demonstrate that TT homozygotes at positions G2677T/A and C3435T required a higher tacrolimus dose than those with wild alleles or heterozygotes. It may be helpful in the prevention of tacrolimus nephrotoxicity early after transplantation.
Proximite territoriale et innovation sens d'une relation Analyse des resultats d'une enquete sur la region de Fes

La proximite a fait l'objet, au cours des dernieres annees, de plus en plus d'interet du point de vue de ses effets potentiels sur l'innovation, ainsi que sur le developpement et la structuration de l'espace economique. De nombreux travaux ont souligne l'importance de la proximite geographique comme source de l'innovation et du developpement de regions competitives. Ces travaux font le lien entre la realisation d'activites innovantes et la colocalisation des acteurs sur un meme territoire. Cette litterature, regroupee sous le terme generique de cluster admet que l'ancrage territorial des membres d'un reseau d'innovation a un impact sur leur capacite a apprendre et a innover collectivement. Doit on en conclure que la simple concentration d'acteurs (entreprises, preneurs de decision, universite) doublee de la proximite physique serait suffisante pour jeter les bases de l'innovation au sein du territoire De nombreux auteurs estiment que les effets potentiels de la proximite geographique ne peuvent se concretiser qu'en la presence au sein du territoire d'une proximite organisee fournie par un cadre institutionnel adequat. La presente etude s'interroge sur le role de la proximite dans le processus de transfert de connaissances et le potentiel d'innovation des entreprises en s'appuyant sur des donnees issues d'une enquete directe aupres de 42 entreprises installees dans la region de Fes. Trois conclusions principales se degagent de cette etude, attestant de l'exigence d'une forme alternative d'organisation du processus d'innovation, moins sensible a la proximite spatiale des acteurs. Tout d'abord, La proximite spatiale n'a pas ete suffisante pour que les entreprises de la region developpent leur capacite d'innovation. Pourtant, l'acces aux reseaux d'information et les interactions personnelles sont des facteurs cles lorsqu'une entreprise entend developper des innovations. L'etude revele ensuite, que les facteurs cles de l'innovation relevent de la qualite des ressources retrouvees a l'echelle locale. Autrement dit, si le fait de cohabiter avec d'autres entreprises importe peu, la qualite de la main d'oeuvre locale, des relations interpersonnelles et la facilite de communiquer influent sur la capacite d'innover d'une entreprise. Enfin, les aspects social, cognitif et communicationnel du territoire sont consideres vitaux par des entrepreneurs pour expliquer l'innovation prenant place au sein d'entreprises de leur secteur d'activites
Authoritative School Climate and High School Student Risk Behavior: A Cross sectional Multi level Analysis of Student Self Reports
Venue: Journal of youth and adolescence

Many adolescents engage in risk behaviors such as substance use and aggression that jeopardize their healthy development. This study tested the hypothesis that an authoritative school climate characterized by strict but fair discipline and supportive teacher student relationships is conducive to lower risk behavior for high school students. Multilevel logistic regression models were used to analyze cross sectional, student report survey data from a statewide sample of 47,888 students (50.6 female) in 319 high schools. The students included ninth (26.6 tenth (25.5 eleventh (24.1 and twelfth (23.8 grade with a racial/ethnic breakdown of 52.2 White, 18.0 Black, 13.1 Hispanic, 5.9 Asian, and 10.8 reporting another or two or more race/ethnicities. Schools with an authoritative school climate had lower levels of student reported alcohol and marijuana use; bullying, fighting, and weapon carrying at school; interest in gang membership; and suicidal thoughts and behavior. These results controlled for demographic variables of student gender, race, grade, and parent education level as well as school size, percentage of minority students, and percentage of low income students. Overall, these findings add new evidence that an authoritative school climate is associated with positive student outcomes.
Sleep Duration and Injury Related Risk Behaviors Among High School Students United States, 2007 2013.
Venue: MMWR. Morbidity and mortality weekly report

Insufficient sleep is common among high school students and has been associated with an increased risk for motor vehicle crashes (1) sports injuries (2) and occupational injuries (3) To evaluate the association between self reported sleep duration on an average school night and several injury related risk behaviors (infrequent bicycle helmet use, infrequent seatbelt use, riding with a driver who had been drinking, drinking and driving, and texting while driving) among U.S. high school students, CDC analyzed data from 50,370 high school students (grades 9 12) who participated in the national Youth Risk Behavior Surveys (YRBSs) in 2007, 2009, 2011, or 2013. The likelihood of each of the five risk behaviors was significantly higher for students who reported sleeping =7 hours on an average school night; infrequent seatbelt use, riding with a drinking driver, and drinking and driving were also more likely for students who reported sleeping =10 hours compared with 9 hours on an average school night. Although insufficient sleep directly contributes to injury risk, some of the increased risk associated with insufficient sleep might be caused by engaging in injury related risk behaviors. Intervention efforts aimed at these behaviors might help reduce injuries resulting from sleepiness, as well as provide opportunities for increasing awareness of the importance of sleep.
Mean cortical curvature reflects cytoarchitecture restructuring in mild traumatic brain injury
Venue: NeuroImage: Clinical

In the United States alone, the number of persons living with the enduring consequences of traumatic brain injuries is estimated to be between 3.2 and 5 million. This number does not include individuals serving in the United States military or seeking care at Veterans Affairs hospitals. The importance of understanding the neurobiological consequences of mild traumatic brain injury (mTBI) has increased with the return of veterans from conflicts overseas, many of who have suffered this type of brain injury. However, identifying the neuroanatomical regions most affected by mTBI continues to prove challenging. The aim of this study was to assess the use of mean cortical curvature as a potential indicator of progressive tissue loss in a cross sectional sample of 54 veterans with mTBI compared to 31 controls evaluated with MRI. It was hypothesized that mean cortical curvature would be increased in veterans with mTBI, relative to controls, due in part to cortical restructuring related to tissue volume loss. Mean cortical curvature was assessed in 60 bilateral regions (31 sulcal, 29 gyral) Of the 120 regions investigated, nearly 50% demonstrated significantly increased mean cortical curvature in mTBI relative to controls with 25% remaining significant following multiple comparison correction (all, pFDR .05) These differences were most prominent in deep gray matter regions of the cortex. Additionally, significant relationships were found between mean cortical curvature and gray and white matter volumes (all, p .05) These findings suggest potentially unique patterns of atrophy by region and indicate that changes in brain microstructure due to mTBI are sensitive to measures of mean curvature.
Epilepsy after Traumatic Brain Injury

An epileptic seizure is a "transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain." Epilepsy is a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures and by the neurobiological, cognitive, psychological, and social consequences of this condition. The widely accepted operational definition of epilepsy requires that an individual have at least two unprovoked seizures on separate days, generally 24 hours apart. An unprovoked seizure refers to a seizure that occurs in the absence of an acute brain insult or systemic disorder. This nosology is based on the observation that while a single unprovoked seizure is often an isolated event that does not recur during an individual's lifetime, two unprovoked seizures rarely occur in isolation and are associated with high risk of the individual experiencing more seizures. In some cases, such as when the seizure occurs in the setting of a potentially epileptogenic brain insult such as an episode of encephalitis or a traumatic brain injury (TBI) it is possible to recognize the specific form of epilepsy at its earliest presentation. In such cases, the diagnosis of epilepsy can be made after the very first unprovoked seizure. Based on its definition, epilepsy is not a single disorder but rather a syndrome or syndromes. Different forms of epilepsy syndrome(s) have different causes, different manifestations, different implications for short and longterm management and treatment, and different outcomes.
Detection of CEA in human serum using surface enhanced Raman spectroscopy coupled with antibody modified Au and g Fe2O3@Au nanoparticles.
Venue: Journal of pharmaceutical and biomedical analysis

In this present work, a rapid and simple method to detect carcinoembryonic antigen (CEA) was developed by using surface enhanced Raman spectroscopy (SERS) coupled with antibody modified Au and g Fe2O3@Au nanoparticles. First, Au@Raman reporter and g Fe2O3@Au were prepared, and then modified with CEA antibody. When CEA was present, the immuno Au@Raman reporter and immuno g Fe2O3@Au formed a complex through antibody antigen antibody interaction. The selective and sensitive detection of CEA could be achieved by SERS after magnetic separation. Under the optimal conditions, a linear relationship was observed between the Raman peak intensity and the concentration of CEA in the range of 1 50 ng mL( 1) with an excellent correlation coefficient of 0.9942. The limit of detection based on two times ratio of signal to noise was 0.1 ng/mL. The recoveries of CEA standard solution spiked with human serum samples were in the range of 88.5 105.9% with the relative standard deviations less than 17.4% The method built was applied to the detection of CEA in human serum, and the relative deviations of the analysis results between the present method and electrochemiluminescence immunoassay were all less than 16.6% The proposed method is practical and has a potential for clinic test of CEA.
Spatial mismatch in post reform urban China: A case study of a relocated state owned enterprise in Guangzhou

Accompanying rapid urbanization and economic transformation, the reconstruction of inner city in urban China has been taking place during recent decades. However, the social and geographic inequality resulted from such reconstruction and experienced by minority groups has received less attention to date. To address this, a case study using individual level data based on a survey of a relocated state owned enterprise (SOE) in Guangzhou was conducted. The study shows that similar to other cities in the world, the spatial mismatch that results in long and time consuming commuting as well as lower quality of life exists. It has considerable adverse impact on the low and middle income employees of the relocated enterprise. However, it was not social or racial segregation but institutional transformation that brought about the spatial mismatch in China. Based on the dual economic system in China, both the planned and market systems played important roles in the enterprise's relocation and their employees' daily lives. Institutional barriers associated with the welfare system had a great impact on the geographic immobility of its employees. These include the retirement and medical insurance systems inherited from the planned economy and the supply of work unit buses, which rendered employees more attached to and dependent on their enterprise. However, these provisions were big burdens to the enterprise which reduced their profit and led to lower spatial mobility of its lower income employees.
Comparison of pile driveability methods based on a case study from an offshore wind farm in North Sea

Significant research effort has been put into pile driveability analyses with the aim of determining a successful, safe and cost efficient installation. Driveability analysis involves selection of appropriate hammer, determination of pile makeup details and careful review of soil profile to reach desired penetration or capacity with reasonable number of blows without overstressing the pile. In this paper, pile driving records from the installation of 6.5 m diameter monopiles at a wind farm in southern North Sea are considered. The ground conditions at the site generally consist of between 10 50 m thickness of over consolidated clay with some layers of sand overlying chalk bedrock. The most important of the variables to establish is the Static Resistance to Driving (SRD) There are proposed procedures for evaluating SRD in sands and clays; however, the knowledge about pile driveability in the chalk at the site is very limited. This makes prediction of the soil response after driving the pile into the chalk layers unreliable. The piling records are used to test how well the existing driveability suit the conditions at this site by comparing the predicted blow counts with results from back analyses of as measured pile driving records.
Dissipation of wind waves by pancake and frazil ice in the autumn Beaufort Sea: WAVE DAMPING BY ICE IN THE BEAUFORT SEA

A model for wind generated surface gravity waves, WAVEWATCH IIIR is used to analyze and interpret buoy measurements of wave spectra. The model is applied to a hindcast of a wave event in sea ice in the western Arctic, 11 14 October 2015, for which extensive buoy and ship borne measurements were made during a research cruise. The model, which uses a viscoelastic parameterization to represent the impact of sea ice on the waves, is found to have good skill after calibration of the effective viscosity for prediction of total energy, but over predicts dissipation of high frequency energy by the sea ice. This shortcoming motivates detailed analysis of the apparent dissipation rate. A new inversion method is applied to yield, for each buoy spectrum, the inferred dissipation rate as a function of wave frequency. For 102 of the measured wave spectra, visual observations of the sea ice were available from buoy mounted cameras, and ice categories (primarily for varying forms of pancake and frazil ice) are assigned to each based on the photographs. When comparing the inversion derived dissipation profiles against the independently derived ice categories, there is remarkable correspondence, with clear sorting of dissipation profiles into groups of similar ice type. These profiles are largely monotonic: they do not exhibit the 'roll over' that has been found at high frequencies in some previous observational studies.
Creative Cognition and Brain Network Dynamics
Venue: Trends in Cognitive Sciences

Creative thinking is central to the arts, sciences, and everyday life. How does the brain produce creative thought? A series of recently published papers has begun to provide insight into this question, reporting a strikingly similar pattern of brain activity and connectivity across a range of creative tasks and domains, from divergent thinking to poetry composition to musical improvisation. This research suggests that creative thought involves dynamic interactions of large scale brain systems, with the most compelling finding being that the default and executive control networks, which can show an antagonistic relation, tend to cooperate during creative cognition and artistic performance. These findings have implications for understanding how brain networks interact to support complex cognitive processes, particularly those involving goal directed, self generated thought.
CAF: Core to core Communication Acceleration Framework
Venue: 2016 International Conference on Parallel Architecture and Compilation Techniques (PACT)

As the number of cores in a multicore system increases, core to core (C2C) communication is increasingly limiting the performance scaling of workloads that share data frequently. The traditional way cores communicate is by using shared memory space between them. However, shared memory communication fundamentally involves coherence invalidations and cache misses, which cause large performance overheads and incur a high amount of network traffic. Many important workloads incur significant C2C communication and are affected significantly by the costs, including pipelined packet processing which is widely used in software based networking solutions. In these workloads, threads run on different cores and pass packets from one core to another for different stages of processing using software queues. In this paper, we analyze the behavior and overheads of software queue management. Based on this analysis, we propose a novel C2C Communication Acceleration Framework (CAF) to optimize C2C communication. CAF offloads substantial communication burdens from cores and memory to a designated, efficient hardware device we refer to as Queue Management Device (QMD) attached to the Network on Chip. CAF combines hardware and software optimizations to effectively reduce the queue induced communication overheads and improve the overall system performance by up to 2 12x over traditional software queue implementations.
A reliable and energy efficient outdoor localisation method for smartphones
Venue: UbiComp 2016

Location has become a key service for smartphone applications. Nowadays, GPS and network based technology have been widely used to provide location service. However, the former suffers its high power consumption, and the latter has some imperfections in location accuracy. In this paper, we present a reliable and energy efficient localisation system using inertial sensors commonly found on today's smartphone. We first give an overall view of the localisation system, and then describe the key components separately. Furthermore, reliable algorithms for displacement determination and heading direction have been developed, and Vincenty's formulae are used to calculate the location of the endpoint. Location error correction mechanisms are also proposed to prevent accumulated error. Evaluation on Samsung I9100 in the real condition confirm anticipated benefits, and results show that ACMG uses 24.7% less power than GPS, and get a mean location accuracy of less than 6.7m in the playground of Nankai University.