nils-herrmann/clean_scirepeval huggingface dataset:
Predicting optimal in vitro culture medium for Pistacia vera micropropagation using neural networks models
Venue: Plant Cell, Tissue and Organ Culture (PCTOC)

In this study, artificial intelligence techniques specifically artificial neural networks (ANNs) in combination with fuzzy logic (neurofuzzy logic) or with genetic algorithms (ANNs GA) have been employed, as modeling tools, to get insight, to predict and to optimize the effect of several independent factors on four growth parameters during Pistacia vera micropropagation. Twenty six media ingredients, including mineral ions (or salts) glycine, vitamins and plant growth regulators (PGRs) at different concentrations, were used as inputs and four growth parameters: proliferation rate, shoot length, total and healthy fresh weight as outputs on the models. The IF THEN rules from neurofuzzy logic models have allowed discovering the positive (BAP, nicotinic acid and pyridoxine HCl) and negative (NO3 Mg2+ Ag+ and gluconate effects on the growth parameters and the fundamental role of BAP over all of them. Also, ANNs GA technology has permitted to estimate the best combination of media ingredients to simultaneously maximize the four parameters of growth: 4.4 new shoots per explant; 28.7 mm length; 1.1 and 0.53 g total and healthy fresh weight, respectively, minimizing physiological disorders. In our opinion, the information obtained in this study is extremely useful to improve the massive multiplication of pistachio plant, in particular, but also demonstrate the ability of artificial intelligence technology to design plant tissue culture media with predictable and tailorable characteristics.
Wearable Sensor Localization Considering Mixed Distributed Sources in Health Monitoring Systems
Venue: Sensors

In health monitoring systems, the base station (BS) and the wearable sensors communicate with each other to construct a virtual multiple input and multiple output (VMIMO) system. In real applications, the signal that the BS received is a distributed source because of the scattering, reflection, diffraction and refraction in the propagation path. In this paper, a 2D direction of arrival (DOA) estimation algorithm for incoherently distributed (ID) and coherently distributed (CD) sources is proposed based on multiple VMIMO systems. ID and CD sources are separated through the second order blind identification (SOBI) algorithm. The traditional estimating signal parameters via the rotational invariance technique (ESPRIT) based algorithm is valid only for one dimensional (1D) DOA estimation for the ID source. By constructing the signal subspace, two rotational invariant relationships are constructed. Then, we extend the ESPRIT to estimate 2D DOAs for ID sources. For DOA estimation of CD sources, two rational invariance relationships are constructed based on the application of generalized steering vectors (GSVs) Then, the ESPRIT based algorithm is used for estimating the eigenvalues of two rational invariance matrices, which contain the angular parameters. The expressions of azimuth and elevation for ID and CD sources have closed forms, which means that the spectrum peak searching is avoided. Therefore, compared to the traditional 2D DOA estimation algorithms, the proposed algorithm imposes significantly low computational complexity. The intersecting point of two rays, which come from two different directions measured by two uniform rectangle arrays (URA) can be regarded as the location of the biosensor (wearable sensor) Three BSs adopting the smart antenna (SA) technique cooperate with each other to locate the wearable sensors using the angulation positioning method. Simulation results demonstrate the effectiveness of the proposed algorithm.
Factors Influencing Business Success in the Garments Industry: A Comparative Analysis between Demographic Factors and HRM Related Factors in Bangladesh

The term 'Business Success' has been conceptualised in many ways. It is related with achieving superior market share, business equilibrium, and positive trend of earning profit. The main aim of this study is to examine and compare the factors influencing business success. It is comparative analysis between the demographic and HRM related factors. The present article is a survey based research. A total of 300 questionnaires were distributed among employees of the garments industries. The data have been analysed using SPSS software. One way ANOVA test along with a model has been developed in order to show and test the relationship among demographic factors and HRM related factors and the business success in this study. The results revealed that individually there is a positive and strong significant influence of educational ability and experience of the employees (demographic factors) job definition, recruitment&selection, performance appraisal, career planning, participation, and compensation (HRM related factors) on businesses success.
Complications of Cytoreductive Surgery and HIPEC in the Treatment of Peritoneal Metastases
Venue: Indian Journal of Surgical Oncology

The combined treatment concept of cytoreductive surgery (CRS) and Hyperthermic intraperitoneal chemotherapy (HIPEC) has shown to be an efficient therapeutic option for selected patients with primary and secondary peritoneal carcinomatosis (PC) This strategy represents the standard of care for diseases like pseudomyxoma peritonei and peritoneal mesothelioma, and offers the best long term results for PC from colorectal cancer. Despite these results, skepticism exists regarding this therapeutic approach partly because of its perceived high toxicity. In this article, we review the current evidence on complications that can occur after CRS and HIPEC and the risk factors associated with increased incidence of morbidity and mortality.
Cytoreductive Surgery plus Hyperthermic Intraperitoneal Chemotherapy for Management of Peritoneal Sarcomatosis: A Preliminary Single Center Experience from Saudi Arabia
Venue: Gastroenterology research and practice

To report our preliminary single center experience with cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) for management of peritoneal sarcomatosis (PS) Methods. Eleven patients were retrospectively analyzed for perioperative details.  Cytoreduction completeness (CC 0/1) was achieved in all patients with median peritoneal cancer index (PCI) of 14 8.9 (range: 3 29) Combination cisplatin doxorubicin HIPEC chemotherapy was used in 6 patients. Five patients received intraoperative radiation therapy (IORT) The median operative time, estimated blood loss, and hospital stay were 8 1.4 hours (range: 6 10) 1000 250 mL (range: 700 3850) and 11 2.4 days (range: 7 15) respectively. Major postoperative Clavien Dindo grade III/IV complications occurred in 1 patient and none developed HIPEC chemotherapy related toxicities. The median overall survival (OS) and disease free survival (DFS) after CRS HIPEC were 28.3 3.2 and 18.0 4.0 months, respectively. The median follow up time was 12 months (range: 6 33) Univariate analysis of several prognostic factors (age, gender, PS presentation/pathology, CC, PCI, HIPEC chemotherapy, and IORT) did not demonstrate statistically significant differences of OS and DFS.  CRS HIPEC appear to be feasible, safe, and offer survival oncological benefits. However, definitive conclusions cannot be deduced.
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease
Venue: Cell

The intestinal microbiota influence neurodevelopment, modulate behavior, and contribute to neurological disorders. However, a functional link between gut bacteria and neurodegenerative diseases remains unexplored. Synucleinopathies are characterized by aggregation of the protein a synuclein (aSyn) often resulting in motor dysfunction as exemplified by Parkinson's disease (PD) Using mice that overexpress aSyn, we report herein that gut microbiota are required for motor deficits, microglia activation, and aSyn pathology. Antibiotic treatment ameliorates, while microbial re colonization promotes, pathophysiology in adult animals, suggesting that postnatal signaling between the gut and the brain modulates disease. Indeed, oral administration of specific microbial metabolites to germ free mice promotes neuroinflammation and motor symptoms. Remarkably, colonization of aSyn overexpressing mice with microbiota from PD affected patients enhances physical impairments compared to microbiota transplants from healthy human donors. These findings reveal that gut bacteria regulate movement disorders in mice and suggest that alterations in the human microbiome represent a risk factor for PD.
ETHNOBOTANICAL STUDY OF SOME PLANTS OF DARGUTI, TEHSIL KHUIRATTA, AZAD JAMMU AND KASHMIR

The ethnobotanical survey on the medicinal plants of Darguti, Tehsil Khuiratta, Azad Jammu and Kashmir was documented during 2014 2015 by interviewing the local inhabitants through a questionnaire. A total of 100 plants species belonging to 47 families were recorded. It was noticed that people uses plants as vegetables and fodder, fuel as well as medicinal purposes. Local people use to cure different diseases like tetanus, diabetes, dysentery, asthma, kidney infection, constipation, gastric ulcer, bronchial diseases, gonorrhea, scabies, throat irritation and many types of skin diseases by using local plants. The most dominant family of this area was Asteraceae. Among 100 plants, 64 have multiple usages, 12 have single usage and 24 have dual usage.
Indigenous knowledge of the use of medicinal plants in Bheri, Muzaffarabad, Azad Kashmir, Pakistan

Indigenous knowledge of medicinal plants can provide information on phytotherapeutic activity for the treatment of disease. The aim of this study was to document and quantify traditional knowledge on the ethnic use of medicinal plants for the treatment of various human diseases by the communities living in Bheri, Muzaffarabad (Pakistan)  Ethno botanical data were collected from ethnic communities using semi structured interviews. Data was analyzed using the informant consensus factor (ICF) the fidelity level (FL) and the medicinal use value (MUV) Moreover, indigenous plant uses were compared with reported phytochemical constituents and their pharmacological properties.  During the survey 80 medicinal plant species used to treat various human ailments were documented. These belonged to 43 families and 69 genera. The plant species identified suggested phytotherapeutic activities for 19 diseases; such as ear pain with the highest ICF (1.00) followed by liver inflammation, cancer, internal injury (0.99) impotency and nervous debility (0.98) A high level of fidelity for Lavatera cashemiriana Morus nigra Rheum australe R. webbianum Bergenia ciliata Melia azedarach (99% Jurinea dolomiaea Solanum nigrum (95% and Trillium govanianum (90% was also recorded.  This study confirmed the traditional uses of plants being used in the indigenous health care system in the study area. A gradual decline of indigenous knowledge in the younger generation was due to socioeconomic changes. There it is a need to promote awareness in local communities on sustainable use and manage in situ and ex situ conservation of flora.
An engineered biocompatible drug delivery system enhances nerve regeneration after delayed repair.
Venue: Journal of biomedical materials research. Part A

Localized drug delivery strategies could greatly benefit patients with peripheral nerve injury and could be easy for surgeons to implement. We developed a local drug delivery system (DDS) using drug loaded poly(lactic co glycolic acid) (PLGA) microspheres (MS) embedded in a fibrin gel. In an in vitro study, we investigated the biocompatibility of this DDS by performing a toxicity assay in which we incubated PC 12 cells with the medium released from the DDS in vitro. In an in vivo study, this DDS was applied at the rat common peroneal (CP) nerve injury site to deliver exogenous glial cell line derived neurotrophic factor (GDNF) to the regenerating axons after delayed nerve repair. In vitro, PC 12 cells incubated with released media samples from the DDS had similar viability to control cells cultured with normal media, demonstrating that the DDS was not toxic. In vivo, the numbers of motor and sensory neurons that regenerated their axons with empty MS treatment were the same as when there was no MS treatment. The DDS increased the numbers of regenerating motor and sensory neurons to levels indistinguishable from those observed with immediate nerve repair. The DDS increased neuron regeneration to levels double those observed with negative control groups. This biocompatible, nontoxic, fibrin gel based DDS enhances outcomes following severe peripheral nerve injuries.
Clay nanocomposites as engineered drug delivery systems

Clays belong to a category of silica layered ingredients that are commonly used in the pharmaceutical industry, either as ingredients or in combination in composites and hybrids. The specific structure of clay provides effective drug delivery systems with the ability to interact with drugs and to control release. Numerous research articles have been published in this respect and valuable results reported, mostly for oral routes. However, overview and discussion of the recent and rapidly growing research along with their theoretical principles are required for understanding and exploring the great potential of this method. To further this aim, we have provided an illustrated and comprehensive study from the point of view of a nanotechnologist, interested in investigating clay aggregate effects at the nano and meso scales for the development of nano composites and hybrids accomplished with clay. In the first stage, a review of the molecular structure and physicochemical properties of clay are discussed and then we continue with a survey of clay and nanoclay origins, preparation methods, modification and incorporation as nano hybrids, nano composites, and nano and microfibers. Also their effects on drug overdose toxicity and on the mechanism of drug loading and release are discussed. Finally, this review summarizes further expansions of their progressive usage in biopharmaceutical applications with the help of integration of release methods and engineering of nanostructured clays in polymeric nanocomposites.
Exosome based tumor antigens adjuvant co delivery utilizing genetically engineered tumor cell derived exosomes with immunostimulatory CpG DNA.
Venue: Biomaterials

For cancer immunotherapy via tumor antigen vaccination in combination with an adjuvant, major challenges include the identification of a particular tumor antigen and efficient delivery of the antigen as well as adjuvant to antigen presenting cells. In this study, we proposed an efficient exosome based tumor antigens adjuvant co delivery system using genetically engineered tumor cell derived exosomes containing endogenous tumor antigens and immunostimulatory CpG DNA. Murine melanoma B16BL6 cells were transfected with a plasmid vector encoding a fusion streptavidin (SAV; a protein that binds to biotin with high affinity) lactadherin (LA; an exosome tropic protein) protein, yielding genetically engineered SAV LA expressing exosomes (SAV exo) SAV exo were combined with biotinylated CpG DNA to prepare CpG DNA modified exosomes (CpG SAV exo) Fluorescent microscopic observation revealed the successful modification of exosomes with CpG DNA by SAV biotin interaction. CpG SAV exo showed efficient and simultaneous delivery of exosomes with CpG DNA to murine dendritic DC2.4 cells in culture. Treatment with CpG SAV exo effectively activated DC2.4 cells and enhanced tumor antigen presentation capacity. Immunization with CpG SAV exo exhibited stronger in vivo antitumor effects in B16BL6 tumor bearing mice than simple co administration of exosomes and CpG DNA. Thus, genetically engineered CpG SAV exo is an effective exosome based tumor antigens adjuvant co delivery system that will be useful for cancer immunotherapy.
Gender and Speech in a Disney Princess Movie

One of the latest Disney princess movies is Frozen which was released in 2013. Female characters in Frozen differ from the female characters in previous Disney movies, such as The Little Mermaid and Tangled. In comparison, female characters in Frozen are portrayed as having more heroic values and norms, which makes it interesting to examine their speech characteristics. Do they use typical female speech despite having more heroic characteristics? This paper aims to provide insights into the female speech characteristics in this movie based on Lakoff's (1975) model of female speech. Data analysis shows that female and male characters in the movie used almost equal number of female speech elements in their dialogues. Interestingly, although female characters in the movie do not behave stereotypically, their speech still contain the elements of female speech, such as the use empty adjectives, questions, hedges and intensifier. This paper argues that the blurring of boundaries between male and female speech characteristics in this movie is an attempt to break gender stereotyping by showing that female characters share similar characteristics with heroic male characters thus they should not be seen as inferior to the male characters.
The Expressive Moment: How Interaction (with Music) Shapes Human Empowerment

The expressive moment is that point in time when we grasp a situation and respond quickly, even before we are aware of it. In this book, Marc Leman argues that expression drives this kind of interaction, and he proposes a general framework for understanding expressive interactions. He focuses on the dynamic, fast, and pre reflective processes underlying our interactions with music whether we are playing an instrument, dancing, listening, or using new interactive technologies. Music offers a well established domain for studying these fast and interactive processes, and Leman argues that understanding the power of expressive interaction through music may help us understand cognitive processing in other domains, including language, human action coordination, human animal interaction, and human machine interaction.Leman regards expressive interactions with music as energizing and empowering. He argues that music is based on patterns that intervene with a reinforcing loop in the human brain, strengthening learning, motivation, and reward. He argues further that the reinforcing effect is influenced by the interaction flow, by fast processes that handle expressive qualities on the fly.Leman sets out the framework in which expressive interaction is situated, describing, among other things, a pragmatic model of communication in which the fundamental components are enactment and dynamics. He looks in more detail at the cognitive motivational architecture, discussing sensorimotor and motivational schemes. Finally, he discusses applications for the concepts behind expressive motivation in such fields as sports, entertainment, rehabilitation, multimedia art, and music education.
Operator Collusion and Market Regulation Policies for Wireless Spectrum Management
Venue: IEEE Transactions on Mobile Computing

The liberalization of wireless communication services markets and the subsequent competition among network operators, is expected to foster optimal utilization of the scarce wireless spectrum and ensure the provision of cost efficient services to users. However, such markets may function inefficiently due to collusion of operators which yields a de facto monopoly. Although it is illegal and detrimental to the users, creation of such cartels arises often in the form of implicit price fixing. In this paper, we consider a general such market where a set of operators sell communication services to a large population of users. We use an evolutionary game model to capture the user dynamics in selecting operators, under limited information about the actual service quality, and we analyze the anticipated interaction of the operators using coalitional game theory. We define a coalition formation game in order to rigorously study the conditions that render monopolistic or oligopolistic markets stable under different notions of coalition stability. We also provide direct and indirect regulation methods, such as setting price upper bounds or allocating different amounts of spectrum, in order to discourage undesirable equilibriums. Our approach provides intuitions about collusion strategies, as well as on directions for identifying and preventing them.
Survey on information system security risk management alignment
Venue: 2016 International Conference on Information Technology for Organizations Development (IT4OD)

Nowadays, the business services of organizations depend widely on Information Systems (IS) However, these systems may face potential failure or risks that could lead to a business failure. Therefore, the Information System Security Risk management (ISSRM) in organizations is ultimate for business success. ISSRM protects the information availability, integrity, and privacy. The aim of this paper is first to assess the security oriented modeling languages through the ISSRM domain model. For this purpose, a survey of the ISSRM alignment in comparison with the security modeling languages is outlined.
Preparation and crystal structure of K2Ce(PO4)2: a new complex phosphate of Ce(iv) having structure with one dimensional channels.
Venue: Dalton transactions

In this manuscript we report crystal structure of a new complex binary phosphate K2Ce(4+(PO4)2 in K2O P2O5 CeO2 system prepared by solid state reaction at moderate temperature conditions. The prepared material was characterized by powder X ray diffraction using lab source and synchrotron radiation as well as thermal analyses, Raman scattering, FTIR, and X ray photoelectron spectroscopic studies. The crystal structure of the compound has been determined from powder XRD data by ab initio structure solution in direct space followed by Rietveld refinements. K2Ce(PO4)2 crystallizes in a monoclinic (P21/n) lattice with unit cell parameters: a 9.1060(4) b 10.8160(5) c 7.6263(4) A, b 111.155(2)deg, V 700.50(6) A(3) The unit cell contains two distinguishable PO4 tetrahedra and one CeO8 distorted square anti prism. Raman spectroscopy confirmed the presence of isolated PO4(3 groups in the structure. These PO4 tetrahedra are connected to one CeO8 polyhedra by sharing one edge and three other CeO8 polyhedra by sharing corners to form the three dimensional structure and empty channels parallel to a axis. The channels are occupied by two crystallographically distinguishable K( ions which maintain the charge neutrality. Contrast to the earlier reported composition K4Ce2P4O15, this study revealed the composition in actual is K4Ce2P4O16 with Ce in 4+ oxidation state and is also supported by X ray photoelectron spectroscopic and X ray absorption near edge structure studies. Differential scanning calorimetric studies revealed a structural transition around 525 degC which reverts on cooling with a large thermal hysteresis. At higher temperature it undergoes a loss of oxygen atom and subsequently loss of phosphorus as P2O5. These thermal effects are also supported by in situ high temperature XRD studies. Finally the crystal chemistry of complex phosphates with tetravalent cations is also discussed.