nils-herrmann/clean_scirepeval huggingface dataset:
Ideal operating conditions for a variable stiffness transverse plane adapter for individuals with lower-limb amputation.
Venue: Journal of biomechanics

Transverse plane shear stress between the prosthetic socket and residual limb often results in soft tissue breakdown and discomfort for individuals with lower-limb amputation. To better understand the effects of reduced transverse plane stiffness in the shank of a prosthesis, a second-generation variable stiffness torsion adapter (VSTA II) was tested with individuals with a transtibial amputation (n = 10). Peak transverse plane moments, VSTA II deflection, range of whole body angular momentum (WBAM), ground reaction impulse, joint work, and personal stiffness preference were evaluated at three fixed stiffness levels (compliant: 0.25 Nm/°, intermediate: 0.75 Nm/°, stiff: 1.25 Nm/°) at three walking speeds (self-selected, fast and slow: +/- 20% of self-selected, respectively) while straight-line walking and performing left and right turns. Residual limb loading decreased and VSTA II displacement increased for reductions in stiffness and both metrics increased with increasing walking speed, while ground reaction impulse and joint work were unaffected. The range of WBAM increased with decreased stiffness, which suggests an increased risk of falling when using the VSTA II at lower stiffness settings. Preference testing showed no significant result, but trends for lower stiffness settings when turning and walking at self-selected speeds were noted, as were stiffer settings when walking straight and at faster speeds. These results show that a device with rotational compliance like the VSTA II could reduce loading on the residual limb during straight walking and turning activities and that factors such as walking speed, activity type and user preference can affect the conditions for optimal use.
Impact attenuation of male and female lacrosse helmets using a modal impulse hammer.
Venue: Journal of biomechanics

It has been established that substantial negative changes in neurocognitive function can be observed in a large percentage of athletes who participate in contact sports such as soccer or football, motivating a need for improved safety systems. Head accelerations in men's lacrosse are similar to those in football and female lacrosse players experience high rates of concussions, necessitating better head protection in both sports. Previous studies have sought to evaluate the ability of modern football helmets to mitigate impacts both normal and oblique to the surface of the helmet using a system that quantifies both the input load and the resulting accelerations of a Hybrid III headform. This study quantifies the inputs and outputs of the helmet-Hybrid III headform system in order to compare the impact attenuation capability of two male and two female lacrosse helmets. Of those helmets tested, the better performing male helmet was the Schutt Stallion 650 and the better performing female helmet was the Hummingbird excepting device failure at the rear boss impact location, but football helmets still generally outperformed the lacrosse helmets tested here.
On the computation of hemodynamic forces in the heart chambers.
Venue: Journal of biomechanics

The hemodynamic forces exchanged between the blood flowing in the heart and the myocardium are recently receiving attention as an important marker of cardiac function. The increasing interest was associated to the advent of advanced imaging methods able to measure the blood velocity field inside the cardiac chambers, from which flow forces are obtained as volume integral of the fluid momentum. These technologies, however, require costly equipment and time-consuming procedures. A different formulation of the balance of momentum, introduced here, permits the computation of hemodynamic forces from geometric and velocity data at the boundary of the blood volume, without the need of measuring the blood velocity inside. This method is valid in generic geometry and is verified in a relatively complex geometry by comparison with results from direct numerical simulation. This approach may permit to integrate the description of cardiac function based on volumetric changes and myocardial deformation with those of hemodynamic forces.
Modelling the dynamic margins of stability for use in evaluations of balance following a support-surface perturbation.
Venue: Journal of biomechanics

The dynamic margin of stability provides a method that captures the center of mass (CoM) state (position-velocity) in relation to the base of support (BoS). However, the model upon which this concept was derived does not consider how the inertial characteristics of forced support-surface perturbations would influence balance control. Within the current article, the inverted pendulum model was restructured to account for fixed, piecewise accelerations of the BoS. From this logic, two variations of the adjusted margin of stability, each maintaining a similar definition of extrapolated CoM, are proposed; one ignoring horizontal ground contact and inertial forces applied to the BoS, the other incorporating these forces. Unique within the proposed models is the time-variant BoS boundaries that depend on the perturbation applied. Verification of the solution for each model is provided, along with a comparison of obtained values to previous methods of defining CoM position-velocity stability metrics using a computational model and optimal control. For the simpler model variation (ignoring forces), we also assessed how CoM position and perturbation parameter selection over/underestimate the predicted maximal permissible velocity. The results of these analyses suggest that factors which increase the acceleration impulse decrease the difference between the two models; the opposite was observed for factors increasing displacements between the CoM and BoS boundary. Lastly, use of the proposed adjusted margin of stability within an experimental data set highlights the ability of our model to predict instability (stepping strategies; negative margin of stability) relative to the use of the extrapolated CoM alone.
Estimation of gait kinematics and kinetics from inertial sensor data using optimal control of musculoskeletal models.
Venue: Journal of biomechanics

Inertial sensing enables field studies of human movement and ambulant assessment of patients. However, the challenge is to obtain a comprehensive analysis from low-quality data and sparse measurements. In this paper, we present a method to estimate gait kinematics and kinetics directly from raw inertial sensor data performing a single dynamic optimization. We formulated an optimal control problem to track accelerometer and gyroscope data with a planar musculoskeletal model. In addition, we minimized muscular effort to ensure a unique solution and to prevent the model from tracking noisy measurements too closely. For evaluation, we recorded data of ten subjects walking and running at six different speeds using seven inertial measurement units (IMUs). Results were compared to a conventional analysis using optical motion capture and a force plate. High correlations were achieved for gait kinematics (ρ⩾0.93) and kinetics (ρ⩾0.90). In contrast to existing IMU processing methods, a dynamically consistent simulation was obtained and we were able to estimate running kinetics. Besides kinematics and kinetics, further metrics such as muscle activations and metabolic cost can be directly obtained from simulated model movements. In summary, the method is insensitive to sensor noise and drift and provides a detailed analysis solely based on inertial sensor data.
Mandibular biomechanics after marginal resection: Correspondences of simulated volumetric strain and skeletal resorption.
Venue: Journal of biomechanics

Serious mandibular diseases such as tumor or osteonecrosis often require segmental or marginal mandibulectomy, the latter with improved outcome thanks to preserved mandibular continuity. Nevertheless, gradual osteolytic and/or osteosclerotic skeletal changes frequently indicate repetitive resections. Based on the fundamental adaptivity of bone to mechanical loads, the question arose whether resection-related anatomical alterations trigger relevant pathological skeletal adaptations. For a clinical case after mandibular box resection due to progressive osteoradionecrosis (ORN), routine biomechanical loading was simulated by finite element method, respecting pathology-related anatomy, tissue properties, and biting capacity. By 3D-visualization of the mandible's pathological development from follow-up-CT's over four years, remarkable correspondences of skeletal resorptions and increased unphysiological strain were revealed. Higher unphysiological load was correlated with more serious and earlier skeletal alterations. Three months post-operatively, serious buccal destruction at the distal resection corner occurred in correspondence with dominant tensile strain. At the resection, elevated strain caused by reduced alveolar height corresponded to skeletal compromise, observed 8-9 months post-operatively. ORN-related lesions, diagnosed before resection, entailed unphysiological strain coinciding with local skeletal alterations. Simulations with "healthy" instead of pathological tissue coefficients induced quantitative improvements of 25-33%, but without fundamental change. These results suggest a decisive contribution of resection-related biomechanical skeletal adaptations to this patient's mandibular decline with hemimandibulectomy about 2.5 years after the first resection. However, mechanical stress concentrations in sharp angles as the distal resection corner and reduced stability due to decreased alveolar height generally bear the danger of pathological biomechanics and severe skeletal adaptations for patients after mandibular box resection.
Maximum velocity during loaded countermovement jumps obtained with an accelerometer, linear encoder and force platform: A comparison of technologies.
Venue: Journal of biomechanics

The maximum velocity (Vmax) reached during countermovement jumps (CMJ) has been considered a performance indicator to evaluate vertical jump ability. The aim of this study was to compare Vmax during loaded CMJ (CMJloaded) using three different technologies to show a criterion for selecting the more appropriate depending on its use. Nine recreationally active men performed a CMJloaded test. Five jumps were made in each of 6 series with a 20- kg barbell + 0, + 5, + 10, + 15, + 20 and + 25 kg, with 2 seconds rest between the jumps and 5 minutes rest between the series to explore a wide range of speeds. Vmax was obtained from force platform, inertial device and linear encoder technologies. Bland-Altman plots and mean differences were used to compare devices. Reproducibility was tested using the intraclass correlation coefficient (ICC) for single measures and typical error (TE). All technologies showed high levels of reproducibility, ICC higher than 0.75 and TE lower than 10 %. There were non-significant differences in Vmax between each pair of technologies (linear encoder 2.11 ± 0.24 m·s-1, accelerometer 2.11 ± 0.26 m·s-1, force platform 2.12 ± 0.24 m·s-1) reporting a very low bias. However the limits of agreement between the different technologies evaluated were high (± 0.33 m·s-1). In conclusion, the accelerometer, linear encoder and force platform were suitably reliable to be used to measure Vmax during loaded vertical jumps but their values were not interchangeable.
Trunk-Pelvis motions and spinal loads during upslope and downslope walking among persons with transfemoral amputation.
Venue: Journal of biomechanics

Larger trunk and pelvic motions in persons with (vs. without) lower limb amputation during activities of daily living (ADLs) adversely affect the mechanical demands on the lower back. Building on evidence that such altered motions result in larger spinal loads during level-ground walking, here we characterize trunk-pelvic motions, trunk muscle forces, and resultant spinal loads among sixteen males with unilateral, transfemoral amputation (TFA) walking at a self-selected speed both up ("upslope"; 1.06 ± 0.14 m/s) and down ("downslope"; 0.98 ± 0.20 m/s) a 10-degree ramp. Tri-planar trunk and pelvic motions were obtained (and ranges-of-motion [ROM] computed) as inputs for a non-linear finite element model of the spine to estimate global and local muscle (i.e., trunk movers and stabilizers, respectively) forces, and resultant spinal loads. Sagittal- (p = 0.001), frontal- (p = 0.004), and transverse-plane (p < 0.001) trunk ROM, and peak mediolateral shear (p = 0.011) and local muscle forces (p = 0.010) were larger (respectively 45, 35, 98, 70, and 11%) in upslope vs. downslope walking. Peak anteroposterior shear (p = 0.33), compression (p = 0.28), and global muscle (p = 0.35) forces were similar between inclinations. Compared to previous reports of persons with TFA walking on level ground, 5-60% larger anteroposterior and mediolateral shear observed here (despite ∼0.25 m/s slower walking speeds) suggest greater mechanical demands on the low back in sloped walking, particularly upslope. Continued characterization of trunk motions and spinal loads during ADLs support the notion that repeated exposures to these larger-than-normal (i.e., vs. level-ground walking in TFA and uninjured cohorts) spinal loads contribute to an increased risk for low back injury following lower limb amputation.
The effect of using different coordinate systems on in-vivo hip angles can be estimated from computed tomography images.
Venue: Journal of biomechanics

Measurements of hip kinematics inherently depend on the coordinate system in which they are derived, yet the effect of the coordinate system definition on calculations of hip angles is not well-understood. Herein, hip angles calculated during dynamic activities were compared using coordinate systems described in the literature. In-vivo kinematic data of 24 participants (13 males) were analyzed during gait and the anterior impingement test using dual fluoroscopy and model-based tracking. Two coordinate systems for the pelvis (anterior pelvic plane, International Society of Biomechanics [ISB]) and three coordinate systems for the femur (table top plane with two definitions of the superior-inferior axis, ISB) were evaluated. Bony landmarks visible on computed tomography (CT) images were identified to establish each coordinate system and used as the basis to calculate differences in hip angles between coordinate system pairs. In the analysis during gait, the maximum differences derived from various coordinate system definitions were 6.7° ± 5.5° for flexion, 7.7° ± 2.1° for rotation, and 5.5° ± 0.7° for adduction. For the anterior impingement test, the differences were 8.1° ± 5.9°, 7.1° ± 1.2°, and 5.3° ± 0.7°, respectively. Landmark-based analysis using CT images could estimate these dynamic differences with errors less than 1.0°. Our results indicate that hip angles can be accurately transformed to angles calculated in different coordinate systems by accounting for the inherent bony anatomy. This information may aid in the interpretation of results across biomechanical studies of the hip.
Musculoskeletal full-body models including a detailed thoracolumbar spine for children and adolescents aged 6-18 years.
Venue: Journal of biomechanics

Currently available musculoskeletal inverse-dynamics thoracolumbar spine models are entirely based on data from adults and might therefore not be applicable for simulations in children and adolescents. In addition, these models lack lower extremities, which are required for comprehensive evaluations of functional activities or therapeutic exercises. We therefore created OpenSim-based musculoskeletal full-body models including a detailed thoracolumbar spine for children and adolescents aged 6-18 years and validated by comparing model predictions to in vivo data. After combining our recently developed adult thoracolumbar spine model with a lower extremity model, children and adolescent models were created for each year of age by adjusting segmental length and mass distribution, center of mass positions and moments of inertia of the major body segments as well as sagittal pelvis and spine alignment based on literature data. Similarly, muscle strength properties were adjusted based on CT-derived cross-sectional area measurements. Simulations were conducted from in vivo studies reported in the literature involving children and adolescents evaluating maximum trunk muscle strength (MTMS), lumbar disc compressibility (LDC), intradiscal pressure (IDP) and trunk muscle activity (MA). Model predictions correlated highly with in vivo data (MTMS: r ≥ 0.82, p ≤ 0.03; LDC: r = 0.77, p < 0.001; IDP: r ≥ 0.78, p < 0.001; MA: r ≥ 0.90, p < 0.001), indicating suitability for the reasonably accurate prediction of maximal trunk muscle strength, segmental loading and trunk muscle activity in children and adolescents. When aiming at investigating children or adolescents with pathologies such as idiopathic scoliosis, our models can serve as a basis for the creation of deformed spine models and for comparative purposes.
Does the margin of stability measure predict medio-lateral stability of gait with a constrained-width base of support?
Venue: Journal of biomechanics

This study aimed to determine the validity of the centre of mass position (COM) position and extrapolated COM (XCOM), relative to the base of support, for predicting medio-lateral stability during a walking task where the base of support width is limited. Nine young healthy participants walked on a narrow beam. Three-dimensional motion capture was used to calculate the COM and XCOM relative to the base of support. Steps were classified as having either the COM or XCOM inside or outside the base of support, and were classified as successful (stable - foot placed on the beam) or failed (unstable - foot stepped off the beam). If the COM or XCOM are valid measures of stability, they should be within the base of support for successful steps and outside the base of support for failed steps. Classifying the COM and XCOM inside or outside the base of support correctly predicted successful or failed steps in 69% and 58% of cases, respectively. When the COM or XCOM were outside the base of support, walking faster seemed to help participants to maintain stability. The further the COM or XCOM were outside the base of support during a successful step, the more likely participants were to fail on a subsequent step. The results of this study suggest that both COM and XCOM are valid measures of stability during a beam walking task, but that classifying COM and XCOM as inside or outside the base of support may be over-simplistic.
Neural muscle activation detection: A deep learning approach using surface electromyography.
Venue: Journal of biomechanics

The timing of muscles activation which is a key parameter in determining plenty of medical conditions can be greatly assessed by the surface EMG signal which inherently carries an immense amount of information. Many techniques for measuring muscle activity detection exist in the literature. However, due to the complex nature of the EMG signal as well as the interference from other muscles that is observed during the measurement of the EMG signal, the accuracy of these techniques is compromised. In this paper, we introduce the neural muscle activation detection (NMAD) framework that detects the muscle activation based on deep learning. The main motivation behind using deep learning is to allow the neural network to detect based on the appropriate signal features instead of depending on certain assumptions. Not only the presented approach significantly improves the accuracy of timing detection, but because of the training nature, it can adapt to operate under different levels of interference and signal-to-noise ratio.
Investigation of balance strategy over gait cycle based on margin of stability.
Venue: Journal of biomechanics

This study was conducted to investigate the balance strategy of healthy young adults through a gait cycle using the margin of stability (MoS). Thirty healthy young adults participated in this study. Each performed walking five times at a preferred speed and at a fast speed. The MoS was calculated over a gait cycle by defining the base of support (BoS) changes during a gait cycle. The MoS was divided into medial/lateral and anterior/posterior components (ML MoS and AP MoS). The central values and the values at 12 gait events of the MoS were compared. Positive/negative integration of ML MoS (ML MoSPOS and ML MoSNEG, respectively) and the average ML/AP MoS over a cycle (ML/AP MoSmean) were significantly lower at a fast gait than at a preferred gait. ML/AP MoS were lower at a fast speed than at the preferred speed, except for the ML MoS immediately before left heel strike (pre left HS) and right and left heel strike (HS). ML/AP MoS were significantly lower immediately before heel strike (pre-HS) than in other gait events, regardless of walking speed. It was suggested that pre-HS is the most unstable moment in both ML/AP directions and a crucial moment in control of gait stability. The results presented above might be applicable as basic data regarding dynamic stability of healthy young adults through a gait cycle for comparisons with elderly people and patients with orthopedic disorders or neurological disorders.
Functionally distinct tendons have different biomechanical, biochemical and histological responses to in vitro unloading.
Venue: Journal of biomechanics

Tendons with different in vivo functions are known to have different baseline biomechanics, biochemistry and ultrastructure, and these can be affected by changes in loading. However it is not know whether different tendon types respond in the same, or different ways, to changes in loading. This study performed in vitro un-loading (stress deprivation) in culture on ovine medial extensor tendons (MET, a positional tendon), and superficial and deep digital flexor tendons (SDFTs and DDFTs, with energy-storing and intermediate functions respectively), for 21 days (n = 14 each). Tensile strength and elastic modulus were then measured, followed by biochemical assays for sulphated glycosaminoglycan (sGAG) and hydroxyproline content. Histological inspection for cell morphology, cell density and collagen alignment was also performed. The positional tendon (MET) had a significant reduction (∼50%) in modulus and strength (P < 0.001) after in vitro stress-deprivation, however there were no significant effects on the energy-storing tendons (SDFT and DDFT). In contrast, sGAG was not affected in the MET, but was reduced in the SDFT and DDFT (P < 0.001). All tendons lost compactness and collagen organisation, and had reduced cell density, but these were more rapid in the MET than the SDFT and DDFT. These results suggest that different tendon types respond to identical stimuli in different ways, thus; (i) the results from an experiment in one tendon type may not be as applicable to other tendon types as previously thought, (ii) positional tendons may be particularly vulnerable to clinical stress-deprivation, and (iii) graft tendon source may affect the biological response to loading in ligament and tendon reconstruction.