Sontag pertenece al Comité Editorial de las siguientes revistas científicas: "IEE Proceedings Systems Biology", "SIAM Review", "Synthetic and Systems Biology", "International Journal of Biological Sciences", "Journal of Computer and Systems Sciences", así como al Comité Asesor de "Neural Computing Surveys", y ha pertenecido a los comités editoriales de "IEEE Transactions in Automatic Control", "Systems and Control Letters", "Dynamics and Control", "Neurocomputing", "Neural Networks", "Control-Theory and Advanced Technology", y "Control, Optimization and the Calculus of Variations".