Muchas compañías automovilísticas utilizan CATIA en distintos grados, incluyendo BMW, Porsche, McLaren Automotive, Chrysler, Honda, Audi, Jaguar Land Rover, Volkswagen, SEAT, Škoda, Bentley Motors Limited, Volvo, Fiat, Benteler International, PSA Peugeot Citroën, Renault, Toyota, Ford, Scania, Hyundai, Tesla Motors, Rolls-Royce Motors, Valmet Automotive, Proton, Elba, Tata motors and Mahindra & Mahindra Limited.