この協会は、1990年に設立され、 2003年に博物館と契約を結び、博物館にスタッフを配置し、歴史的なアウトリーチを実施し、乗客の話を調査し、家族の再会に似た大規模な年次イベントを主催している。

孤児列車に孤児を送り出した施設
孤児列車に乗った子どもたちの多くは以下の施設から送り出されてきた(一部抜粋リスト)

Angel Guardian Home 
Association for Befriending Children & Young Girls 
Association for Benefit of Colored Orphans 
Baby Fold 
Baptist Children's Home of Long Island 
Bedford Maternity, Inc. 
Bellevue Hospital 
Bensonhurst Maternity 
Berachah Orphanage 
Berkshire Farm for boys 
Berwind Maternity Clinic 
Beth Israel Hospital 
Bethany Samaritan Society 
Bethlehem Lutheran Children's Home 
Booth Memorial Hospital 
Borough Park Maternity Hospital 
Brace Memorial Newsboys House 
Bronx Maternity Hospital 
Brooklyn Benevolent Society 
Brooklyn Hebrew Orphan Asylum 
Brooklyn Home for Children 
Brooklyn Hospital 
Brooklyn Industrial school 
Brooklyn Maternity Hospital 
Brooklyn Nursery & Infants Hospital 
Brookwood Child Care 
Catholic Child Care Society 
Catholic Committee for Refugees 
Catholic Guardian Society 
Catholic Home Bureau 
Child Welfare League of America 
Children's Aid Society 
Children's Haven 
Children's Village, Inc. 
Church Mission of Help 
Colored Orphan Asylum 
Convent of Mercy 
Dana House 
Door of Hope 
Duval College for Infant Children 
Edenwald School for Boys 
Erlanger Home 
Euphrasian Residence 
Family Reception Center 
Fellowship House for boys 
Ferguson House 
Five Points House of Industry 
Florence Crittendon League 
Goodhue Home 
Grace Hospital 
Graham Windham Services 
Greer-Woodycrest Children's Services 
Guardian Angel Home 
Guild of the Infant Savior 
Hale House for Infants, Inc. 
Half-Orphan Asylum 
Harman Home for Children 
Heartsease Home 
Hebrew Orphan Asylum 
Hebrew Sheltering Guardian Society 
Holy Angels' School 
Home for Destitute Children 
Home for Destitute Children of Seamen 
Home for Friendless Women and Children 
Hopewell Society of Brooklyn 
House of the Good Shepherd 
House of Mercy 
House of Refuge 
Howard Mission & Home for Little Wanderers 
Infant Asylum 
Infants' Home of Brooklyn 
Institution of Mercy 
Jewish Board of Guardians 
Jewish Protector & Aid Society 
Kallman Home for Children 
Little Flower Children's Services 
Maternity Center Association 
McCloskey School & Home 
McMahon Memorial Shelter 
Mercy Orphanage 
Messiah Home for Children 
Methodist Child Welfare Society 
Misericordia Hospital 
Mission of the Immaculate Virgin 
Morrisania City Hospital 
Mother Theodore's Memorial Girls' Home 
Mothers & Babies Hospital 
Mount Siani Hospital 
New York Foundling Hospital 
New York Home for Friendless Boys 
New York House of Refuge
Children's Village|New York Juvenile Asylum (Children's Village)
New York Society for Prevention of Cruelty to Children
Ninth St. Day Nursery & Orphans' Home 
Orphan Asylum Society of the City of Brooklyn 
Orphan House 
Ottilie Home for Children

メディアの中で描かれた孤児列車
 Big Brother by Annie Fellow-Johnson, an 1893 children's fiction book.
 Extra! Extra! The Orphan Trains and Newsboys of New York by Renée Wendinger, an unabridged nonfiction resource book and pictorial history about the orphan trains. 
 Good Boy (Little Orphan at the Train), ノーマン・ロックウェルの絵 - 子ども満載の列車、修道尼が抱きかかえた男の子と後ろに隠れる女の子、それに呼びかける良家の奥様
 "Eddie Rode The Orphan Train", a song by Jim Roll and covered by Jason Ringenberg
 Last Train Home: An Orphan Train Story, a 2014 historical novella by Renée Wendinger 
 Orphan Train (film)|Orphan Train, a 1979 television film directed by William A. Graham.
 "Rider on an Orphan Train", a song by David Massengill from his 1995 album The Return
 Christina Baker Kline#Orphan Train|Orphan Train, a 2013 novel by Christina Baker Kline(邦訳・クリスティーナ・ベイカー・クライン『孤児列車』作品社 2015年)
 Placing Out, a 2007 documentary sponsored by the Kansas Humanities Council
 トイ・ストーリー3, a 2010 Pixar animated film in which "Orphan Train" is referenced briefly at 00:02:04 - 00:02:07. 里親家庭の人間関係は、このシリーズ全体を通して繰り返し登場する。