{"gt_parse": {"text_sequence": "tic deficiencie s.Genetic defi ciencies in the cr eatine biosynt hetic pathway lead to various severe n eurological defects. Clinically t here are three distinct disord ers of creati ne metabolism . Deficiencies i n the two synthes is enzymes can cau se caused by var iants in \"GATM\" an d guanidinoacetate m et hylt ra ns fer as e de fic iency caused by variants in \"GAMT\"."}}